MCID: LYM009
MIFTS: 45

Lymphocytic Choriomeningitis malady

Categories: Infectious diseases, Neuronal diseases, Immune diseases

Aliases & Classifications for Lymphocytic Choriomeningitis

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Aliases & Descriptions for Lymphocytic Choriomeningitis:

Name: Lymphocytic Choriomeningitis 10 47 12 36 2 65
Lcm 10 2
Lymphocytic Choriomeningitis Virus Encephalomyelitis 10
 
Non-Arthropod Borne Lymphocytic Choriomeningitis 65
Lymphocytic Meningoencephalitis 10
Lymphocytic Meningitis 10

Classifications:



External Ids:

Disease Ontology10 DOID:12155
ICD1027 A87.2
ICD9CM29 049.0
MeSH36 D008216
UMLS65 C0024266, C0153014

Summaries for Lymphocytic Choriomeningitis

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Disease Ontology:10 A viral infectious disease that results in infection located in brain, or located in meninges, or located in brain and meninges, has material basis in Lymphocytic choriomeningitis virus, which is transmitted by common house mouse, Mus musculus. The infection has symptom fever, has symptom lack of appetite, has symptom headache, has symptom muscle aches, has symptom malaise, has symptom nausea, and has symptom vomiting.

MalaCards based summary: Lymphocytic Choriomeningitis, also known as lcm, is related to mantle cell lymphoma and mollaret meningitis, and has symptoms including fever, lack of appetite and headache. An important gene associated with Lymphocytic Choriomeningitis is DAG1 (Dystroglycan 1). Affiliated tissues include brain, meninges and t cells.

Wikipedia:68 Lymphocytic choriomeningitis (LCM), is a rodent-borne viral infectious disease that presents as aseptic... more...

Related Diseases for Lymphocytic Choriomeningitis

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Graphical network of the top 20 diseases related to Lymphocytic Choriomeningitis:



Diseases related to lymphocytic choriomeningitis

Symptoms for Lymphocytic Choriomeningitis

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Symptoms:

 10 (show all 7)
  • fever
  • lack of appetite
  • headache
  • muscle aches
  • malaise
  • nausea
  • vomiting

Drugs & Therapeutics for Lymphocytic Choriomeningitis

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Lymphocytic Choriomeningitis


Cochrane evidence based reviews: lymphocytic choriomeningitis

Genetic Tests for Lymphocytic Choriomeningitis

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Anatomical Context for Lymphocytic Choriomeningitis

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MalaCards organs/tissues related to Lymphocytic Choriomeningitis:

33
T cells, Brain, Liver, Heart, Breast, B cells, Lung

FMA organs/tissues related to Lymphocytic Choriomeningitis:

16
Brain, Meninges

Animal Models for Lymphocytic Choriomeningitis or affiliated genes

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MGI Mouse Phenotypes related to Lymphocytic Choriomeningitis:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes

Publications for Lymphocytic Choriomeningitis

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Articles related to Lymphocytic Choriomeningitis:

(show top 50)    (show all 541)
idTitleAuthorsYear
1
Lymphocytic choriomeningitis and alpha-chemokines. (26152632)
2015
2
Human plasmacytoid dendritic cells sense lymphocytic choriomeningitis virus-infected cells in vitro. (24155390)
2014
3
Interleukin-1R signaling is essential for induction of proapoptotic CD8 T cells, viral clearance, and pathology during lymphocytic choriomeningitis virus infection in mice. (22674984)
2012
4
Self-association of lymphocytic choriomeningitis virus nucleoprotein is mediated by its N-terminal region and is not required for its anti-interferon function. (22258244)
2012
5
Lymphocytic choriomeningitis virus: an underrecognized cause of neurologic disease in the fetus, child, and adult. (22889536)
2012
6
Viral replicative capacity is the primary determinant of lymphocytic choriomeningitis virus persistence and immunosuppression. (21098292)
2010
7
Lymphocytic choriomeningitis virus meningitis, New York, NY, USA, 2009. (20113573)
2010
8
The alternative NF-kappaB signalling pathway is a prerequisite for an appropriate immune response against lymphocytic choriomeningitis virus infection. (20565293)
2010
9
Lymphocytic choriomeningitis virus: a prenatal and postnatal threat. (19968943)
2009
10
Lymphocytic choriomeningitis virus uses a novel endocytic pathway for infectious entry via late endosomes. (18554681)
2008
11
A lymphocytic choriomeningitis virus glycoprotein variant that is retained in the endoplasmic reticulum efficiently cross-primes CD8(+) T cell responses. (17686978)
2007
12
Quantitating the magnitude of the lymphocytic choriomeningitis virus-specific CD8 T-cell response: it is even bigger than we thought. (17151096)
2007
13
Congenital viral infections of the brain: lessons learned from lymphocytic choriomeningitis virus in the neonatal rat. (18052527)
2007
14
Survey of lymphocytic choriomeningitis virus diagnosis and testing--Connecticut, 2005. (16617288)
2006
15
Congenital lymphocytic choriomeningitis virus: an underdiagnosed cause of neonatal hydrocephalus. (16732159)
2006
16
Type 1 IFN deficiency in the absence of normal splenic architecture during lymphocytic choriomeningitis virus infection. (16920967)
2006
17
CNS activity of Pokeweed anti-viral protein (PAP) in mice infected with lymphocytic choriomeningitis virus (LCMV). (15725345)
2005
18
Urolithiasis associated with experimental lymphocytic choriomeningitis virus inoculation in Lewis rats. (15253279)
2004
19
Endoproteolytic processing of the lymphocytic choriomeningitis virus glycoprotein by the subtilase SKI-1/S1P. (12584310)
2003
20
Detection of lymphocytic choriomeningitis virus by use of fluorogenic nuclease reverse transcriptase-polymerase chain reaction analysis. (12625508)
2003
21
Control of lymphocytic choriomeningitis virus infection in granzyme B deficient mice. (12504535)
2003
22
Role of the virus nucleoprotein in the regulation of lymphocytic choriomeningitis virus transcription and RNA replication. (12610166)
2003
23
Identification of the lymphocytic choriomeningitis virus (LCMV) proteins required to rescue LCMV RNA analogs into LCMV-like particles. (12021374)
2002
24
NP and L proteins of lymphocytic choriomeningitis virus (LCMV) are sufficient for efficient transcription and replication of LCMV genomic RNA analogs. (10729120)
2000
25
Retroviral vectors pseudotyped with lymphocytic choriomeningitis virus. (10364368)
1999
26
Inducible nitric-oxide synthase plays a minimal role in lymphocytic choriomeningitis virus-induced, T cell-mediated protective immunity and immunopathology. (10580062)
1999
27
Enhanced virus clearance by early inducible lymphocytic choriomeningitis virus-neutralizing antibodies in immunoglobulin-transgenic mice. (9499083)
1998
28
Cytolytically active memory CTL present in lymphocytic choriomeningitis virus-immune mice after clearance of virus infection. (9164957)
1997
29
Lymphocytic choriomeningitis virus: a new addition to the TORCH evaluation. (9152144)
1997
30
Congenital lymphocytic choriomeningitis virus infection. (8634744)
1996
31
T-cell-mediated immunity to lymphocytic choriomeningitis virus in beta2-integrin (CD18)- and ICAM-1 (CD54)-deficient mice. (8971031)
1996
32
Lymphocytic choriomeningitis virus: a neglected central nervous system pathogen. (8825010)
1996
33
Murine hepatitis caused by lymphocytic choriomeningitis virus. II. Cells involved in pathogenesis. (7745950)
1995
34
Concurrent sequence analysis of 5' and 3' RNA termini by intramolecular circularization reveals 5' nontemplated bases and 3' terminal heterogeneity for lymphocytic choriomeningitis virus mRNAs. (7682625)
1993
35
Replication of lymphocytic choriomeningitis virus is restricted in terminally differentiated neurons. (8230458)
1993
36
Altered cytokine genes expression by conA-activated spleen cells from mice infected by lymphocytic choriomeningitis virus. (7685735)
1993
37
Immunosuppression in mice by lymphocytic choriomeningitis virus infection: time dependence during primary and absence of effects on secondary antibody responses. (2170031)
1990
38
Infection of guinea pigs with two strains of lymphocytic choriomeningitis virus. (2130208)
1990
39
IFN-gamma production in tissues of mice during acute infection with lymphocytic choriomeningitis virus. (2109012)
1990
40
In vivo selection of lymphocyte-tropic and macrophage-tropic variants of lymphocytic choriomeningitis virus during persistent infection. (1976825)
1990
41
Perturbation of differentiated functions during viral infection in vivo. In vivo relationship of host genes and lymphocytic choriomeningitis virus to growth hormone deficiency. (2221020)
1990
42
Cytotoxic T lymphocyte control of acute lymphocytic choriomeningitis virus infection: interferon gamma, but not tumour necrosis factor alpha, displays antiviral activity in vivo. (2514255)
1989
43
An acquired immune suppression in mice caused by infection with lymphocytic choriomeningitis virus. (2452742)
1988
44
State of viral genome and proteins during persistent lymphocytic choriomeningitis virus infection. (2435462)
1987
45
Lack of correlation between serum titres of interferon alpha, beta, natural killer cell activity and clinical susceptibility in mice infected with two isolates of lymphocytic choriomeningitis virus. (3612089)
1987
46
Biology of cloned cytotoxic T lymphocytes specific for lymphocytic choriomeningitis virus. VI. Migration and activity in vivo in acute and persistent infection. (2416821)
1986
47
Immunosuppression in experimental trypanosomiasis: effects of Trypanosoma brucei on immunization against louping-ill virus and lymphocytic choriomeningitis virus. (232108)
1979
48
Pathogenesis of cerebellar hypoplasia produced by lymphocytic choriomeningitis virus infection of neonatal rats. 1. Evolution of disease following infection at 4 days of age. (4568304)
1973
49
Requirement for theta-bearing cells in lymphocytic choriomeningitis virus-induced central nervous system disease. (4561841)
1972
50
Cerebellar hypoplasia in neonatal rats caused by lymphocytic choriomeningitis virus. (4992415)
1971

Variations for Lymphocytic Choriomeningitis

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Expression for genes affiliated with Lymphocytic Choriomeningitis

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Search GEO for disease gene expression data for Lymphocytic Choriomeningitis.

Pathways for genes affiliated with Lymphocytic Choriomeningitis

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GO Terms for genes affiliated with Lymphocytic Choriomeningitis

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Biological processes related to Lymphocytic Choriomeningitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1natural killer cell differentiationGO:00017799.5AXL, TYRO3
2forebrain cell migrationGO:00218859.4AXL, TYRO3
3secretion by cellGO:00329409.3AXL, TYRO3
4vagina developmentGO:00600689.0AXL, TYRO3

Sources for Lymphocytic Choriomeningitis

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet