MCID: LYM042
MIFTS: 32

Lymphocytic Colitis malady

Categories: Rare diseases, Gastrointestinal diseases, Immune diseases

Aliases & Classifications for Lymphocytic Colitis

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Sources:
10Disease Ontology, 45NIH Rare Diseases, 12DISEASES, 51Orphanet, 36MeSH, 65UMLS, 27ICD10, 42NCIt, 59SNOMED-CT, 28ICD10 via Orphanet, 37MESH via Orphanet, 66UMLS via Orphanet
See all MalaCards sources

Aliases & Descriptions for Lymphocytic Colitis:

Name: Lymphocytic Colitis 10 45 12 51
 
Colitis, Lymphocytic 36 65

Classifications:



External Ids:

Disease Ontology10 DOID:0060184
ICD1027 K52.89
MeSH36 D046730
NCIt42 C27147
SNOMED-CT59 31437008
Orphanet51 65279
ICD10 via Orphanet28 K52.8
MESH via Orphanet37 D046730
UMLS via Orphanet66 C0400822
UMLS65 C0400822

Summaries for Lymphocytic Colitis

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NIH Rare Diseases:45 Lymphocytic colitis is form of microscopic colitis, a condition that is characterized by inflammation of the colon (large intestines). as the name suggests, microscopic colitis can only be diagnosed by examining a small sample of colon tissue under a microscope. in lymphocytic colitis, specifically, the tissues and lining of the colon are of normal thickness, but an increase in the number of lymphocytes (a type of white blood cell) is observed. signs and symptoms of the condition may include chronic, watery diarrhea; abdominal pain, cramping, and bloating; weight loss; nausea; dehydration; and/or fecal incontinence. the underlying cause of lymphocytic colitis is currently unknown; however, scientists suspect that autoimmune conditions, medications, infections, genetic factors, and/or bile acid malabsorption may contribute to the development of the condition. treatment is based on the signs and symptoms present in each person and may include certain medications, dietary modifications, and in rare cases, surgery. last updated: 4/6/2016

MalaCards based summary: Lymphocytic Colitis, also known as colitis, lymphocytic, is related to transient arthritis and microscopic colitis. An important gene associated with Lymphocytic Colitis is CHGA (Chromogranin A), and among its related pathways are Celecoxib Pathway, Pharmacodynamics and Development Endothelin-1/EDNRA signaling. Affiliated tissues include colon, bone and breast, and related mouse phenotype homeostasis/metabolism.

Disease Ontology:10 A colitis characterized by an accumulation of lymphocytes in the colonic epithelium and connective tissue (lamina propria).

Wikipedia:68 Lymphocytic colitis is a subtype of microscopic colitis, a condition characterized by chronic non-bloody... more...

Related Diseases for Lymphocytic Colitis

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Graphical network of the top 20 diseases related to Lymphocytic Colitis:



Diseases related to lymphocytic colitis

Symptoms for Lymphocytic Colitis

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Drugs & Therapeutics for Lymphocytic Colitis

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Drugs for Lymphocytic Colitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 21)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
BudesonideapprovedPhase 3, Phase 238151333-22-363006, 5281004
Synonyms:
(11-beta,16-alpha)-16,17-(Butylidenebis(oxy))-11,21-dihydroxypregna-1,4-diene-3,20-dione
(11beta,16alpha)-16,17-(Butylidenebis(oxy))-11,21-dihydroxypregna-1,4-diene-3,20-dione
(4aR,4bS,5S,6aS,6bS,8R,9aR,10aS,10bS)-5-hydroxy-6b-(hydroxyacetyl)-4a,6a-dimethyl-8-propyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one
(4aR,4bS,5S,6aS,6bS,9aR,10aS,10bS)-5-hydroxy-6b-(hydroxyacetyl)-4a,6a-dimethyl-8-propyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one
(R,S)-11b,16a,17,21,tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with buty raldehyde
(RS)-(11beta,16alpha)-16,17-[Butylidenebis(oxy)]-11,21-dihydroxypregna-1,4-diene-3,20-dione
(RS)-11beta,16alpha,17,21-Tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with butyraldehyde
(S)-16alpha,17-(Butylidenedioxy)-11beta,21-dihydroxypregna-1,4-diene-3,20-dione
11beta,21-dihydroxy-16alpha,17alpha-(butane-1,1-diyldioxy)pregna-1,4-diene-3,20-dione
16,17-Butylidenebis(oxy)-11,21-dihydroxypregna-1,4-diene-3,20-dione
16,17-Butylidenebis(oxy)-11-,21-dihydroxypregna-1,4-diene-3,20-dione
16-alpha,17-alpha-Butylidenedioxy-11-beta,21-dihydroxy-1,4-pregnadiene-3,20-dione
16alpha(R),17-(Butylidenebis(oxy))-11beta,21-dihydroxypregna-1,4-diene-3,20-dione
16alpha-,17alpha--butylidenedioxypregna-1,4-diene-11beta-,21-diol-3,20-dione
51333-22-3
AC-4697
AC1L1DQE
AC1L1Y6Y
AC1L22VC
AC1MHWI7
B 7777
B7777_SIGMA
BPBio1_000523
BRD-A34299591-001-03-4
BRD-A82238138-001-01-7
BSPBio_000475
BSPBio_002160
Bidien
Bio-0010
Budecort Inhaler
Budenofalk
Budeson
Budesonide
Budesonide (JAN/USAN/INN)
Budesonide Easyhaler
Budesonide Inhalation
Budesonide MMX
Budesonide Nasal
Budesonide [USAN:INN:BAN:JAN]
Budesonido
Budesonido [INN-Spanish]
Budesonidum
Budesonidum [INN-Latin]
Budiair
Budicort
C25H34O6
CCRIS 5230
CHEBI:3207
CHEBI:656601
CHEMBL1370
CID2462
CID3033890
CID40000
CID5281004
CID63006
CPD000058337
Cortivent
D00246
DB01222
Desowen
Dexbudesonide
Dexbudesonide [INN]
DivK1c_000475
EINECS 257-139-7
EINECS 257-160-1
EINECS 257-161-7
EU-0100174
Entocort
Entocort EC
Entocort EC (TN)
Giona Easyhaler
HMS1569H17
HMS1921I22
HMS2094I13
HMS501H17
 
Horacort
IDI1_000475
Inflammide
KBio1_000475
KBio3_001660
KBioGR_001361
LS-187734
LS-7235
Lopac0_000174
MAP-0010
MLS000028507
MLS001077323
MLS002207112
Micronyl
Miflonide
MolPort-002-529-265
MolPort-003-666-332
MolPort-003-986-909
NCGC00015165-03
NCGC00021318-03
NCGC00021318-06
NCGC00089747-02
NCGC00089747-03
NCGC00089747-04
NCGC00178789-01
NINDS_000475
Noex
Preferid
Pregna-1,4-diene-3,20-dione, 16,17-butylidenebis(oxy)-11,21-dihydroxy-, (11beta,16alpha(R))-, and 16alpha,17-((S)-Butylidenebis(oxy))-11beta,21-dihydroxypregna-1,4-diene-3,20-dione
Prestwick0_000518
Prestwick1_000518
Prestwick2_000518
Prestwick3_000518
Prestwick_840
Pulmaxan
Pulmaxan turbohaler
Pulmicort
Pulmicort (TN)
Pulmicort FLEXHALER
Pulmicort Flexhaler
Pulmicort Nebuamp
Pulmicort Respules
Pulmicort Topinasal
Pulmicort Turbuhaler
Pulmicort turbuhaler
Respules
Rhinocort
Rhinocort Aqua
Rhinocort Turbuhaler
Rhinocort alpha
Rhinocort, Pulmicort , Entocort, Symbicort, Noex. Entocort EC, Budesonide
Rhinosol
S 1320
S-1320
S1286_Selleck
SAM002699898
SMR000058337
SPBio_000586
SPBio_002396
SPECTRUM1500813
ST51039033
Spectrum2_000623
Spectrum3_000620
Spectrum4_000821
Spectrum5_001738
Spirocort
TL8003397
Tridesilon
UDB
UNII-168L5HT37P
UNII-2HI1006KPH
UNII-Q3OKS62Q6X
Uceris
Unit dose budesonide
ZINC03938751
ZINC04097286
budesonide
2Peripheral Nervous System AgentsPhase 3, Phase 218510
3Hormones, Hormone Substitutes, and Hormone AntagonistsPhase 3, Phase 29988
4Respiratory System AgentsPhase 3, Phase 23931
5Anti-Asthmatic AgentsPhase 3, Phase 22796
6HormonesPhase 3, Phase 211748
7Hormone AntagonistsPhase 3, Phase 210002
8Anti-Inflammatory AgentsPhase 3, Phase 28478
9Bronchodilator AgentsPhase 3, Phase 22377
10glucocorticoidsPhase 3, Phase 23896
11MesalaminePhase 315289-57-6
12Antirheumatic AgentsPhase 38496
13AnalgesicsPhase 39358
14Analgesics, Non-NarcoticPhase 35184
15Anti-Inflammatory Agents, Non-SteroidalPhase 33549
16Pharmaceutical Solutions7004
17Gastrointestinal Agents6401
18
Bismuth1037440-69-916682734, 105143
Synonyms:
17034_FLUKA
24267-48-9
25243-76-9
264008_ALDRICH
265462_ALDRICH
265470_ALDRICH
452386_ALDRICH
556130_ALDRICH
7440-69-9
83Bi
95372_ALDRICH
95372_FLUKA
95375_FLUKA
AC1NSDYX
AC1O4PN8
AR-1I0647
BISMUTH, 99.95%
 
BISMUTH, 99.999%
Bi
Bismut
Bismuth standard for AAS
Bismuth standard for ICP
Bismuth(III) nitrate solution
Bismuth, elemental
Bismuth-209
C15471
CHEBI:33301
CID5359367
EINECS 231-177-4
HSDB 2078
LS-44708
LTBB002773
MolPort-003-925-759
Wismut
bismuth
bismuto
19Anti-Ulcer Agents1453
20Antacids1453
21ColaNutraceutical1768

Interventional clinical trials:

idNameStatusNCT IDPhase
1Budesonide Treatment for Lymphocytic ColitisCompletedNCT00180050Phase 3
2Budesonide Versus Mesalazine Versus Placebo in Lymphocytic ColitisRecruitingNCT01209208Phase 3
3Budesonide Versus Placebo for the Treatment of Lymphocytic ColitisTerminatedNCT00217022Phase 2, Phase 3
4Usefulness of Chromoendoscopy in Diagnosing Microscopic ColitisRecruitingNCT01504048
5Case-Control Study to Identify Risk Factors for Microscopic ColitisEnrolling by invitationNCT01928667
6Treatment of Microscopic ColitisTerminatedNCT00184171

Search NIH Clinical Center for Lymphocytic Colitis


Cochrane evidence based reviews: colitis, lymphocytic

Genetic Tests for Lymphocytic Colitis

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Anatomical Context for Lymphocytic Colitis

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MalaCards organs/tissues related to Lymphocytic Colitis:

33
Colon, Bone, Breast, Prostate, Lung, Monocytes, Bone marrow

Animal Models for Lymphocytic Colitis or affiliated genes

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MGI Mouse Phenotypes related to Lymphocytic Colitis:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053767.4ATP4A, CHGA, IRAK2, MMP9, PTGER4, PYY

Publications for Lymphocytic Colitis

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Articles related to Lymphocytic Colitis:

(show top 50)    (show all 105)
idTitleAuthorsYear
1
Features and outcome of a glomerulonephropathy associated with ligneous conjunctivitis in a Doberman pinscher dog. (27152037)
2016
2
Use of additional absorbent pad in the skin preparation and draping of breast patients to reduce rates of contact dermatitis. (26492912)
2015
3
Clinical Outcome and Quality of Life After a Multimodal Therapy Approach to Ear Keloids. (26270082)
2015
4
Sterile pyuria. (25760357)
2015
5
Mechanism of transient resolution of chronic complete right bundle branch block following an acute anterior myocardial infarction. (26184919)
2015
6
Intronic SH2D1A mutation with impaired SAP expression and agammaglobulinemia. (23280491)
2013
7
A case of chordoma invading multiple neuroaxial bones: report of ten years follow up. (24101282)
2013
8
The Di Bella Method (DBM) in the treatment of prostate cancer: a preliminary retrospective study of 16 patients and a review of the literature. (24378460)
2013
9
Mechanisms of neuroprotection by hemopexin: modeling the control of heme and iron homeostasis in brain neurons in inflammatory states. (23350672)
2013
10
Necrostatin-1 Attenuates Ischemia Injury Induced Cell Death in Rat Tubular Cell Line NRK-52E through Decreased Drp1 Expression. (24351845)
2013
11
High clinical accuracy of asymmetric dimethylarginine and symmetric dimethylarginine in patients with ischemic heart disease. (22555650)
2012
12
Sensory conflict compared in microgravity, artificial gravity, motion sickness, and vestibular disorders. (23000608)
2012
13
Polymorphisms in the transcription factor NRF2 and forearm vasodilator responses in humans. (22668754)
2012
14
Lack of association of genetic variations of deoxycytidine kinase with toxicity or survival of non-small-cell lung cancer patients treated with gemcitabine plus cisplatin. (23035362)
2012
15
Increased familiarity of intellectual deficits in early-onset schizophrenia spectrum disorders. (21812621)
2012
16
Serum acute phase proteins as clinical phase indicators and outcome predictors in naturally occurring canine monocytic ehrlichiosis. (21564293)
2011
17
N88S seipin mutant transgenic mice develop features of seipinopathy/BSCL2-related motor neuron disease via endoplasmic reticulum stress. (21750110)
2011
18
Chronic phase shifts of the photoperiod throughout pregnancy programs glucose intolerance and insulin resistance in the rat. (21494686)
2011
19
Oleanane triterpenoid CDDO-Me induces apoptosis in multidrug resistant osteosarcoma cells through inhibition of Stat3 pathway. (20459702)
2010
20
Promotion of lung carcinogenesis by chronic obstructive pulmonary disease-like airway inflammation in a K-ras-induced mouse model. (18927348)
2009
21
Aberrant receptor internalization and enhanced FRS2-dependent signaling contribute to the transforming activity of the fibroblast growth factor receptor 2 IIIb C3 isoform. (19103595)
2009
22
Novel crosstalk to BMP signalling: cGMP-dependent kinase I modulates BMP receptor and Smad activity. (19424179)
2009
23
A transcription co-factor integrates cell adhesion and motility with the p53 response. (19897726)
2009
24
Multiple genetic factors in olanzapine-induced weight gain in schizophrenia patients: a cohort study. (19193342)
2008
25
p18(Hamlet) mediates different p53-dependent responses to DNA-damage inducing agents. (17700068)
2007
26
Zinc and ageing: third Zincage conference. (17883856)
2007
27
Epigallocatechin-3-gallate inhibits secretion of TNF-alpha, IL-6 and IL-8 through the attenuation of ERK and NF-kappaB in HMC-1 cells. (17135765)
2007
28
Effects of basic fibroblast growth factor on density and morphology of fibroblasts grown on root surfaces with or without conditioning with tetracycline or EDTA. (17928728)
2007
29
Regulation of IL-8 by Irsogladine maleate is involved in abolishment of Actinobacillus actinomycetemcomitans-induced reduction of gap-junctional intercellular communication. (16870466)
2006
30
Intestinal failure in obstructive jaundice. (15968746)
2005
31
Hepatitis caused by tick-borne meningoencephalitis virus (TBEV)--a rare clinical manifestation outside the central nervous system involvement]. (16334744)
2005
32
A proteomic investigation into etoposide chemo-resistance of neuroblastoma cell lines. (15682461)
2005
33
Rosai-Dorfman disease presenting as extranodal renal mass. (16360469)
2005
34
Frequent activation of AKT in non-small cell lung carcinomas and preneoplastic bronchial lesions. (15240509)
2004
35
Bile salt exposure causes phosphatidyl-inositol-3-kinase-mediated proliferation in a Barrett's adenocarcinoma cell line. (15300175)
2004
36
ABO blood type, Lewis and Secretor genotypes, and chronic atrophic gastritis: a cross-sectional study in Japan. (12673421)
2003
37
Increased expression of monocyte chemoattractant protein-1 in atherectomy specimens from patients with restenosis after percutaneous transluminal coronary angioplasty. (11999660)
2002
38
Expression of c-erbB receptors and ligands in the bronchial epithelium of asthmatic subjects. (11799369)
2002
39
Distinct roles for c-Myb and core binding factor/polyoma enhancer-binding protein 2 in the assembly and function of a multiprotein complex on the TCR delta enhancer in vivo. (12370369)
2002
40
Targeting the ets binding site of the HER2/neu promoter with pyrrole-imidazole polyamides. (10818092)
2000
41
Signalling of interleukin-6 type cytokines via gp130, leukemia inhibitory factor (LIF) receptor and oncostatin M receptor. (11203189)
2000
42
Cathepsin B immunohistochemical staining in tumor and endothelial cells is a new prognostic factor for survival in patients with brain tumors. (10100707)
1999
43
Genetic association between monoamine oxidase A microsatellite and RFLP alleles and bipolar affective disorder: analysis and meta-analysis. (8776592)
1996
44
Nature of respiratory stimulation in hyperthyroidism: the redox behaviour of cytochrome c. (7498500)
1995
45
Determinants of cervical ectopia and of cervicitis: age, oral contraception, specific cervical infection, smoking, and douching. (7645632)
1995
46
Respective roles of neurofilaments, microtubules, MAP1B, and tau in neurite outgrowth and stabilization. (7803854)
1994
47
Surfactant proteins A (SP-A) and D (SP-D): levels in human amniotic fluid and localization in the fetal membranes. (8305484)
1994
48
Placental protein 14 levels in uterine flushing and plasma of women with unexplained infertility. (8458460)
1993
49
Tumor necrosis factor and chemotherapeutic agents. Potentiation of cytotoxicity with interferon gamma. (1418895)
1992
50
Biogenesis of the nuclear lamina: in vivo synthesis and processing of nuclear protein precursors. (3515346)
1986

Variations for Lymphocytic Colitis

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Expression for genes affiliated with Lymphocytic Colitis

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Search GEO for disease gene expression data for Lymphocytic Colitis.

Pathways for genes affiliated with Lymphocytic Colitis

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GO Terms for genes affiliated with Lymphocytic Colitis

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Biological processes related to Lymphocytic Colitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1JNK cascadeGO:00072549.5IRAK2, PTGER4

Sources for Lymphocytic Colitis

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet