MCID: LYM015
MIFTS: 31

Lymphocytic Gastritis malady

Categories: Gastrointestinal diseases, Immune diseases

Aliases & Classifications for Lymphocytic Gastritis

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Aliases & Descriptions for Lymphocytic Gastritis:

Name: Lymphocytic Gastritis 11 13 66

Classifications:



External Ids:

Disease Ontology11 DOID:4035
NCIt43 C27051

Summaries for Lymphocytic Gastritis

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MalaCards based summary: Lymphocytic Gastritis is related to gastritis and male infertility. An important gene associated with Lymphocytic Gastritis is GZMB (Granzyme B), and among its related pathways are Downstream signaling in naive CD8+ T cells and IL12-mediated signaling events. Affiliated tissues include t cells.

Related Diseases for Lymphocytic Gastritis

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Diseases related to Lymphocytic Gastritis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 58)
idRelated DiseaseScoreTop Affiliating Genes
1gastritis10.6
2male infertility10.3GZMB, TIA1
3eosinophilia10.3GZMB, TIA1
4subependymal nodular heterotopia10.3GZMB, TIA1
5pseudotyphus of california10.3GZMB, TIA1
6diffuse large b-cell lymphoma with chronic inflammation10.2GZMB, TIA1
7polycystic ovary syndrome10.2GZMB, TIA1
8gray zone lymphoma10.2GZMB, TIA1
9limb dystonia10.2GZMB, TIA1
10renal hypertension10.2GZMB, TIA1
11lumbosacral lipoma10.2GZMB, TIA1
12mixed cell type cancer10.2GZMB, TIA1
13lacrimal passage granuloma10.2GZMB, TIA1
14cardiac granular cell neoplasm10.2B3GAT1, GZMB
15sezary's disease10.2GZMB, TIA1
16sialolithiasis10.2GZMB, TIA1
17estrogen-receptor positive breast cancer10.1GZMB, TIA1
18celiac disease10.1
19tonsillar fossa cancer10.1FAS, GZMB
20lymphoma10.0
21trigeminal nerve disease10.0FASLG, GZMB
22aorta atresia9.9GZMB, TIA1
23gastric lymphoma9.9
24adenocarcinoma9.9
25bolivian hemorrhagic fever9.9FASLG, GZMB
26gastric cancer9.8
27gastric adenocarcinoma9.8
2812p12.1 microdeletion syndrome9.8FAS, FASLG
29hypodermyiasis9.8FASLG, GZMB
30pediatric systemic lupus erythematosus9.8FAS, FASLG
31diverticulitis9.8B3GAT1, FASLG
32clivus chordoma9.8B3GAT1, GZMB, TIA1
33hepatitis b9.8FAS, GZMB
34breast fibroadenosis9.8B3GAT1, GZMB, TIA1
35adrenal cortical adenocarcinoma9.8FAS, FASLG
36metaphyseal dysplasia without hypotrichosis9.8FAS, FASLG
37deficiency anemia9.7
38acne9.7
39gastric ulcer9.7
40iron deficiency anemia9.7
41dyspepsia9.7
42intestinal disease9.7
43duodenitis9.7
44vasculitis9.7
45collagenous gastritis9.7
46hodgkin lymphoma9.7FAS, GZMB, TIA1
47benign breast adenomyoepithelioma9.7FAS, FASLG
48sinusitis9.6FAS, FASLG
49asbestosis9.6FAS, FASLG
50epstein-barr virus, susceptibility to chronic infection by9.6GZMB, TIA1

Graphical network of the top 20 diseases related to Lymphocytic Gastritis:



Diseases related to lymphocytic gastritis

Symptoms for Lymphocytic Gastritis

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Drugs & Therapeutics for Lymphocytic Gastritis

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Drugs for Lymphocytic Gastritis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Proton pump inhibitorsPhase 31057
Synonyms:
 
PPIs
2
EsomeprazolePhase 3317161796-78-7, 119141-88-74594, 9579578
Synonyms:
( -)-Omeprazole
(-)-Omeprazole
(-)-omeprazole
(S)-(-)-Omeprazole
(S)-(−)-omeprazole
(S)-Omeprazole
(S)-omeprazole
(s)-omeprazole
(−)-omeprazole
119141-88-7
119141-89-8
131959-78-9
172964-80-6
193469-77-1
2-(((3,5-Dimethyl-4-methoxy-2-pyridyl)methyl)sulfinyl)-5-methoxy-1H-benzimidazole
2-({[3,5-dimethyl-4-(methyloxy)pyridin-2-yl]methyl}sulfinyl)-5-(methyloxy)-1H-benzimidazole
326602-80-6
5-Methoxy-2-(((4-methoxy-3,5-dimethyl-2-pyridyl)methyl)sulfinyl)benzimidazole
5-Methoxy-2-((S)-((4-methoxy-3,5-dimethyl-2-pyridyl)methyl)sulfinyl)benzimidazole
5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole
5-Methoxy-2[(4-methoxy-3,5-dimethyl-2-pyridyl)methylsulfinyl]-1H-benzimidazole
5-methoxy-2-{(S)-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole
5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1-methyl-1H-benzimidazole
5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole
6-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl]-1H-benzimidazole
6-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole
73590-58-6
AC-401
AC1L1IIJ
AGI-010
AKOS005066653
AULCER
Antra
Antra MUPS
Audazol
Axagon
BIDD:GT0020
BIDD:GT0189
BPBio1_000425
BRD-A55962179-001-04-9
BSPBio_000385
Belmazol
Bio-0888
C07324
CAS-73590-58-6
CCRIS 7099
CHEBI:50275
CHEBI:519601
CHEBI:7772
CHEMBL1503
CID4594
CID9568614
CID9579578
CPD000058847
Ceprandal
D00455
D07917
DB00338
DB00736
DM-3458
Danlox
Demeprazol
Desec
Dizprazol
Dudencer
Elgam
Emeproton
Emilok
Epirazole
Erbolin
Esomeprazol
Esomeprazole
Esomeprazole (INN)
Esomeprazole Sodium
Esomeprazole [INN:BAN]
Esomeprazolum
Esomperazole
Esopral
Exter
Gasec
Gastrimut
Gastroloc
Gibancer
H 168-68
H 168/68
H-168/68
H168/68
HMS1528I05
HMS1569D07
HMS2052G17
HMS2090E16
HMS2090F11
HSDB 3575
I06-0705
IDI1_032523
InChI=1/C17H19N3O3S/c1-10-8-18-15(11(2)16(10)23-4)9-24(21)17-19-13-6-5-12(22-3)7-14(13)20-17/h5-8H,9H2,1-4H3,(H,19,20
Indurgan
Inexium paranova
Inexium paranova (TN)
Inhibitron
Inhipump
LS-185188
LS-7629
Lensor
Logastric
Lomac
Losec
Losec, Omesec, Prilosec, Zegerid, Omeprazole
Lucen
MLS000069373
MLS001076112
MLS001424148
Maybridge4_002645
Mepral
 
Miol
Miracid
MolPort-003-666-741
MolPort-003-807-515
MolPort-003-849-702
MolPort-005-943-880
Mopral
Morecon
NCGC00016925-01
NCGC00016925-02
NCGC00021522-03
NCGC00021522-04
NCGC00021522-05
Nexiam
Nexium
Nexium Control
Nexium IV
Nilsec
Nopramin
Nuclosina
O0359
O104_SIGMA
OMEP
OMZ
Ocid
Olexin
Olit
Omapren
Omebeta
Omebeta 20
Omed
Omegast
Omepradex
Omepral
Omeprazol
Omeprazol [INN-Spanish]
Omeprazole (JAN/USP/INN)
Omeprazole S-form
Omeprazole [USAN:INN:BAN:JAN]
Omeprazole delayed-release
Omeprazole magnesium
Omeprazolum
Omeprazolum [INN-Latin]
Omeprazon
Omeprazone
Omeprol
Omesek
Omez
Omezol
Omezolan
Omid
Omisec
Omizac
Ompanyt
Ortanol
Osiren
Ozoken
Paprazol
Parizac
Pepticum
Pepticus
Peptilcer
Perprazole
Prazentol
Prazidec
Prazolit
Prestwick0_000493
Prestwick1_000493
Prestwick2_000493
Prestwick3_000493
Prestwick_808
Prilosec
Prilosec (TN)
Prilosec OTC
Procelac
Proclor
Prysma
Ramezol
Regulacid
Result
S1389_Selleck
SAM001246900
SAN-15
SMR000058847
SPBio_002306
STK623746
Sanamidol
Secrepina
TL8005099
Tedec Ulceral
UNII-KG60484QX9
UNII-N3PA6559FT
UPCMLD-DP075
UPCMLD-DP075:001
Ulceral
Ulcesep
Ulcometion
Ulcozol
Ulcsep
Ulsen
Ultop
Ulzol
Victrix
ZINC04693574
ZINC04693575
Zefxon
Zegerid
Zepral
Zimor
Zoltum
esomeprazol
esomeprazole
esomeprazolum
omeprazole
Ésoméprazole

Interventional clinical trials:

idNameStatusNCT IDPhase
1Esomeprazole Treatment for Patients With Lymphocytic GastritisRecruitingNCT00455754Phase 3
2Lymphocytic Subsets and Cytokine Production With H. Pylori InfectionCompletedNCT00173953

Search NIH Clinical Center for Lymphocytic Gastritis

Genetic Tests for Lymphocytic Gastritis

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Anatomical Context for Lymphocytic Gastritis

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MalaCards organs/tissues related to Lymphocytic Gastritis:

34
T cells

Animal Models for Lymphocytic Gastritis or affiliated genes

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Publications for Lymphocytic Gastritis

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Articles related to Lymphocytic Gastritis:

(show top 50)    (show all 73)
idTitleAuthorsYear
1
Propionibacterium acnes overabundance and NKG2D system activation in corpus-dominant lymphocytic gastritis. (27538697)
2016
2
Letter: lymphocytic gastritis and coeliac disease. (26331558)
2015
3
Lymphocytic gastritis showing concomitant occurrence of both CD4 + and CD8 + T-cells among epithelial cells. (25047508)
2014
4
Pathology in practice. Severe gastric submucosal edema, with vasculitis, fibrinoid degeneration, and mild eosinophilic and lymphocytic gastritis. (24649989)
2014
5
Lymphocytic gastritis is not associated with active Helicobacter pylori infection. (24826984)
2014
6
High proportion of granzyme B+ intraepithelial lymphocytes contributes to epithelial apoptosis in Helicobacter pylori-associated lymphocytic gastritis. (23356909)
2013
7
Iron deficiency anemia due to lymphocytic gastritis with Helicobacter pylori infection in childhood: case report. (23528908)
2013
8
Lymphocytic gastritis in pediatric celiac disease. (21244234)
2011
9
Endoscopic portrayal of lymphocytic gastritis in a child. (20639772)
2010
10
Lymphocytic gastritis and celiac disease in indian children: evidence of a positive relation. (18979579)
2008
11
The frequency of lymphocytic gastritis in baboons. (18396790)
2008
12
Healing of lymphocytic gastritis after Helicobacter pylori eradication therapy--a randomized, double-blind, placebo-controlled multicentre trial. (16441467)
2006
13
Lymphocytic gastritis in Helicobacter pylori-positive gastric MALT lymphoma--report of two cases. (15908769)
2005
14
Resolution of gastrointestinal protein loss after Helicobacter pylori eradication in a patient with hypertrophic lymphocytic gastritis. (15610076)
2004
15
Lymphocytic gastritis in pediatric celiac disease -- immunohistochemical study of the intraepithelial lymphocytic component. (14704635)
2004
16
Epithelial cell proliferation and glandular atrophy in lymphocytic gastritis: effect of H pylori treatment. (14669318)
2003
17
Collagenous gastritis associated with lymphocytic gastritis and celiac disease. (11735694)
2001
18
Treatment of Helicobacter pylori in patients with lymphocytic gastritis. (11490827)
2001
19
Lymphocytic gastritis and protein-losing gastropathy. (11030189)
2000
20
Lymphocytic gastritis: association with etiology and topology. (9989841)
1999
21
The pattern of involvement of the gastric mucosa in lymphocytic gastritis is predictive of the presence of duodenal pathology. (10690170)
1999
22
Lymphocytic gastritis and coeliac disease: evidence of a positive association. (9659261)
1998
23
Spontaneous remission of hypertrophic lymphocytic gastritis associated with hypoproteinemia. (9932632)
1998
24
Adenocarcinoma of the small bowel, coeliac disease, and lymphocytic gastritis. (10193339)
1998
25
Lymphocytic gastritis and Helicobacter pylori: a Brazilian survey. (9577382)
1998
26
Hypertrophic lymphocytic gastritis with a gastric carcinoma. (9831277)
1998
27
Massive bleeding from multiple gastric ulcerations in a patient with lymphocytic gastritis and celiac sprue. (9412920)
1997
28
Association of Helicobacter pylori infection, lymphoid follicles, and lymphocytic gastritis: a risk factor for the development of primary gastric lymphoma? (8707131)
1996
29
Lymphocytic gastritis and coeliac disease. (8707101)
1996
30
Ten year follow up study of lymphocytic gastritis: further evidence on Helicobacter pylori as a cause of lymphocytic gastritis and corpus gastritis. (8567997)
1995
31
A retrospective study on the incidence of lymphocytic gastritis in patients with Helicobacter pylori infection. (8545561)
1995
32
Lymphocytic gastritis and associated small bowel disease: a diffuse lymphocytic gastroenteropathy? (8537495)
1995
33
Lymphocytic gastritis. Clinical and endoscopic presentation and long-term follow-up. (7571985)
1995
34
Early gastric cancer in a patient with Menetrier's disease, lymphocytic gastritis and Helicobacter pylori. (7712313)
1995
35
Lymphocytic gastritis: a positive relationship with celiac disease. (8283376)
1994
36
Lymphocytic gastritis, gastric adenocarcinoma, and primary gastric lymphoma. (7876391)
1994
37
Animal model of human disease: lymphocytic gastritis. (8110991)
1993
38
Lymphocytic gastritis: an unusual cause of hypoproteinaemia. (8326297)
1993
39
Lymphocytic gastritis and giant gastric folds associated with gastrointestinal protein loss. (2020657)
1991
40
Hypertrophic gastropathy with gastric adenocarcinoma: Menetrier's disease and lymphocytic gastritis? (1773969)
1991
41
The topographic distribution of lymphocytic gastritis in gastrectomy specimens. (1892635)
1991
42
Lymphocytic gastritis in nonulcer dyspepsia. (1864200)
1991
43
MAcnActrier's disease with lymphocytic gastritis: an unusual association with possible pathogenic implications. (2050372)
1991
44
Lymphocytic gastritis in patients with celiac sprue or spruelike intestinal disease. (2295386)
1990
45
Chronic lymphocytic gastritis. (2370021)
1990
46
Lymphocytic gastritis--prospective study of its relationship with varioliform gastritis. (2323590)
1990
47
Lymphocytic gastritis versus varioliform gastritis. A historical series revisited. (2754536)
1989
48
Lymphocytic gastritis: a newly described entity. (18668898)
1989
49
Lymphocytic gastritis: a newly described entity: a retrospective endoscopic and histological study. (3198002)
1988
50
Lymphocytic gastritis--relationship to Campylobacter pylori infection. (3258373)
1988

Variations for Lymphocytic Gastritis

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Expression for genes affiliated with Lymphocytic Gastritis

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Search GEO for disease gene expression data for Lymphocytic Gastritis.

Pathways for genes affiliated with Lymphocytic Gastritis

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Pathways related to Lymphocytic Gastritis according to GeneCards Suite gene sharing:

(show all 13)
idSuper pathwaysScoreTop Affiliating Genes
1
Show member pathways
9.2FASLG, GZMB
2
Show member pathways
9.2FASLG, GZMB
39.0FAS, FASLG
49.0FAS, FASLG
5
Show member pathways
8.6FAS, FASLG, GZMB
6
Show member pathways
8.6FAS, FASLG, GZMB
7
Show member pathways
8.6FAS, FASLG, GZMB
88.6FAS, FASLG, GZMB
9
Show member pathways
8.6FAS, FASLG, GZMB
10
Show member pathways
8.6FAS, FASLG, GZMB
11
Show member pathways
8.6FAS, FASLG, GZMB
12
Show member pathways
8.6FAS, FASLG, GZMB
138.1FAS, FASLG, GZMB, TIA1

GO Terms for genes affiliated with Lymphocytic Gastritis

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Biological processes related to Lymphocytic Gastritis according to GeneCards Suite gene sharing:

(show all 11)
idNameGO IDScoreTop Affiliating Genes
1inflammatory cell apoptotic processGO:00069259.7FAS, FASLG
2necroptotic signaling pathwayGO:00975279.6FAS, FASLG
3activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathwayGO:00972969.6FAS, FASLG
4response to growth factorGO:00708489.5FAS, FASLG
5regulation of extrinsic apoptotic signaling pathway via death domain receptorsGO:19020419.5FAS, FASLG
6extrinsic apoptotic signaling pathwayGO:00971919.5FAS, FASLG
7negative regulation of extrinsic apoptotic signaling pathway via death domain receptorsGO:19020429.4FAS, FASLG
8activation of cysteine-type endopeptidase activity involved in apoptotic processGO:00069199.3FAS, FASLG
9extrinsic apoptotic signaling pathway via death domain receptorsGO:00086259.3FAS, FASLG
10apoptotic signaling pathwayGO:00971909.2FAS, FASLG
11apoptotic processGO:00069158.1FAS, FASLG, GZMB, TIA1

Sources for Lymphocytic Gastritis

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet