MCID: LYM067
MIFTS: 43

Lymphoid Leukemia

Categories: Immune diseases, Cancer diseases

Aliases & Classifications for Lymphoid Leukemia

MalaCards integrated aliases for Lymphoid Leukemia:

Name: Lymphoid Leukemia 38 29 69

Classifications:



Summaries for Lymphoid Leukemia

MalaCards based summary : Lymphoid Leukemia is related to chronic lymphocytic leukemia and hairy cell leukemia. An important gene associated with Lymphoid Leukemia is KMT2A (Lysine Methyltransferase 2A), and among its related pathways/superpathways are Pathways in cancer and NF-kappaB Signaling. The drugs Asparaginase and Cytarabine have been mentioned in the context of this disorder. Affiliated tissues include b cells, t cells and bone, and related phenotypes are growth/size/body region and hematopoietic system

Wikipedia : 72 Lymphoid leukemias — also called lymphocytic, lymphogenous, or lymphoblastic leukemias — are a group of... more...

Related Diseases for Lymphoid Leukemia

Diseases related to Lymphoid Leukemia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 67)
id Related Disease Score Top Affiliating Genes
1 chronic lymphocytic leukemia 11.6
2 hairy cell leukemia 11.2
3 adult acute lymphocytic leukemia 10.9
4 leukemia 10.6
5 ring chromosome 5 10.6 ETV6 KMT2A
6 blake pouch cyst 10.4 CD5 KMT2A
7 deafness, autosomal recessive 8/10 10.2 ETV6 RUNX1
8 bagatelle cassidy syndrome 10.1 CD5 ZAP70
9 hepatic osteogenic sarcoma 10.1 CD5 ZAP70
10 pulmonary valve agenesis-tetralogy of fallot-absence of ductus arteriosus syndrome 10.1 RUNX1 RUNX1T1
11 cd3delta deficiency 10.0 CD5 ZAP70
12 acute necrotizing encephalopathy 10.0 ETV6 KMT2A RUNX1
13 breast osteosarcoma 9.9 ETV6 KMT2A RUNX1
14 myeloid leukemia 9.9
15 acute lymphoblastic leukemia, childhood 9.9 ETV6 KMT2A RUNX1
16 pneumonic plague 9.9 CD5 ZAP70
17 lymphoma 9.9
18 nuchal bleb, familial 9.8 BCR CD5
19 chronic venous leg ulcers 9.8 ETV6 RUNX1
20 duodenal ulcer 9.8 BCR CD5
21 col12a1-related muscle diseases 9.7 BCR RUNX1
22 focal epilepsy 9.7 BCR ETV6
23 lymphosarcoma 9.7
24 myelodysplastic syndrome 9.7
25 spinocerebellar ataxia, autosomal recessive 21 9.6 KMT2A RUNX1 RUNX1T1
26 leukemia, acute myeloid 9.6 ETV6 KMT2A RUNX1
27 acute monocytic leukemia 9.6 ETV6 RUNX1
28 cask-related intellectual disability 9.6 BCR RUNX1
29 arthritis 9.5
30 t-cell leukemia 9.5
31 thyroiditis 9.5
32 hematopoietic stem cell transplantation 9.5
33 vasculitis 9.5
34 hodgkin's granuloma 9.5
35 peripheral t-cell lymphoma 9.5
36 renal tubular acidosis 9.5
37 pemphigus 9.5
38 mucositis 9.5
39 acute leukemia of ambiguous lineage 9.5
40 pulmonary alveolar proteinosis 9.5
41 bone marrow necrosis 9.5
42 bronchopneumonia 9.5
43 superior vena cava syndrome 9.5
44 porphyria cutanea tarda 9.5
45 porphyria 9.5
46 angiomatosis 9.5
47 panniculitis 9.5
48 endotheliitis 9.5
49 multiple myeloma 9.5
50 histoplasmosis 9.5

Comorbidity relations with Lymphoid Leukemia via Phenotypic Disease Network (PDN):


Acute Cystitis Deficiency Anemia
Leukemia, B-Cell, Chronic

Graphical network of the top 20 diseases related to Lymphoid Leukemia:



Diseases related to Lymphoid Leukemia

Symptoms & Phenotypes for Lymphoid Leukemia

MGI Mouse Phenotypes related to Lymphoid Leukemia:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 growth/size/body region MP:0005378 9.87 SH3GL1 BCR ETV6 KMT2A NCKIPSD RUNX1
2 hematopoietic system MP:0005397 9.73 BCR CD5 ETV6 KMT2A RUNX1 ZAP70
3 integument MP:0010771 9.63 CD5 ETV6 KMT2A RUNX1 RUNX1T1 ZAP70
4 no phenotypic analysis MP:0003012 9.35 CD5 ETV6 KMT2A NCKIPSD RUNX1
5 normal MP:0002873 9.23 BCR CD5 ETV6 KMT2A RUNX1 RUNX1T1

Drugs & Therapeutics for Lymphoid Leukemia

Drugs for Lymphoid Leukemia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 688)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Asparaginase Approved Phase 4,Phase 3,Phase 2,Phase 1 9015-68-3
2
Cytarabine Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1 147-94-4 6253
3
Daunorubicin Approved Phase 4,Phase 3,Phase 2,Phase 1 20830-81-3 30323
4
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1 50-02-2 5743
5
Idarubicin Approved Phase 4,Phase 3,Phase 2,Phase 1 58957-92-9 42890
6
Methotrexate Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 1959-05-2, 59-05-2 126941
7
Vincristine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 2068-78-2, 57-22-7 5978
8
Cyclophosphamide Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 50-18-0, 6055-19-2 2907
9
Doxorubicin Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 23214-92-8 31703
10
Pegaspargase Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 130167-69-0
11
Lenograstim Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 135968-09-1
12
Methylprednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 83-43-2 6741
13
Prednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 50-24-8 5755
14
rituximab Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 174722-31-7 10201696
15
Adenosine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 58-61-7 60961
16
Pentostatin Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 53910-25-1 40926 439693
17
Cladribine Approved, Investigational Phase 4,Phase 3,Phase 1,Phase 2 4291-63-8 20279
18
Etoposide Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 33419-42-0 36462
19
Fludarabine Approved Phase 4,Phase 3,Phase 2,Phase 1 21679-14-1, 75607-67-9 30751
20
Teniposide Approved Phase 4,Phase 3,Phase 2 29767-20-2 34698
21
Thioguanine Approved Phase 4,Phase 3,Phase 2,Phase 1 154-42-7 2723601
22
Vindesine Approved Phase 4,Phase 3,Phase 2 59917-39-4, 53643-48-4 40839
23
Ifosfamide Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 3778-73-2 3690
24
Prednisone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 53-03-2 5865
25
Chlorambucil Approved Phase 4,Phase 3,Phase 2,Phase 1 305-03-3 2708
26
Hydrocortisone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 50-23-7 5754 657311
27
Mitoxantrone Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 65271-80-9 4212
28
Vidarabine Approved Phase 4,Phase 3,Phase 2,Phase 1 24356-66-9 32326 21704
29 Thiotepa Approved Phase 4,Phase 3,Phase 2,Phase 1 52-24-4 5453
30
Busulfan Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 55-98-1 2478
31
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 22916-47-8 4189
32
Dasatinib Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1 302962-49-8 3062316
33
Valganciclovir Approved, Investigational Phase 4,Phase 2 175865-60-8 64147
34
Dopamine Approved Phase 4 51-61-6, 62-31-7 681
35
Methylphenidate Approved, Investigational Phase 4 113-45-1 4158
36
Oprelvekin Approved, Investigational Phase 4 145941-26-0
37
Menthol Approved Phase 4 2216-51-5 16666
38
Micafungin Approved, Investigational Phase 4,Phase 2 235114-32-6 3081921 477468
39
Posaconazole Approved, Investigational, Vet_approved Phase 4 171228-49-2 147912
40
Amphotericin B Approved, Investigational Phase 4,Phase 3,Phase 2 1397-89-3 14956 5280965
41
Nicotine Approved Phase 4 54-11-5 942 89594
42
Folic Acid Approved, Nutraceutical, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 59-30-3 6037
43
leucovorin Approved, Nutraceutical Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 58-05-9 143 6006
44
Cholecalciferol Approved, Nutraceutical Phase 4,Phase 3,Phase 2,Early Phase 1 67-97-0 6221 10883523 5280795
45
Vitamin D Approved, Nutraceutical, Vet_approved Phase 4,Phase 3,Phase 2,Early Phase 1 1406-16-2
46
Ergocalciferol Approved, Nutraceutical Phase 4,Phase 3,Phase 2,Early Phase 1 50-14-6 5280793
47
Doxil Approved June 1999 Phase 4,Phase 3,Phase 2,Phase 1 31703
48
Butyric Acid Experimental Phase 4,Phase 3,Phase 2,Phase 1 107-92-6 264
49
Treosulfan Investigational Phase 4,Phase 3,Phase 2,Phase 1 299-75-2 9296
50 Anti-Bacterial Agents Phase 4,Phase 3,Phase 2,Phase 1

Interventional clinical trials:

(show top 50) (show all 2631)

id Name Status NCT ID Phase Drugs
1 Treatment Protocol of Children With Philadelphia Chromosome Negative High Risk Acute Lymphoblastic Leukemia Unknown status NCT01990807 Phase 4 Idarubicin(IDA)
2 Medical Research Council (MRC) Working Party on Leukaemia in Children UK National Acute Lymphoblastic Leukaemia (ALL) Trial: UKALL 2003 Unknown status NCT00222612 Phase 4 Standard childhood UK ALL protocol;Intensified treatment including Capizzi maintenance
3 German Multicenter Trial for Treatment of Elderly Patients With Newly Diagnosed Acute Lymphoblastic Leukemia Unknown status NCT00198978 Phase 4 Cyclophosphamide;Dexamethasone / Prednisolone;Cytarabine;Idarubicin;Granulocyte-Colony-Stimulating Factor;Mercaptopurine;Methotrexate;Rituximab;HDARAC;Vincristine;Depocyte;Asparaginase
4 Efficacy and Safety of Nipent, Cytoxan and Rituxan in the Treatment of Chronic Lymphocytic Leukemia. Unknown status NCT00131313 Phase 4 Nipent, Cytoxan, Rituxan
5 German Multicenter Trial for Treatment of Newly Diagnosed Acute Lymphoblastic Leukemia in Adults (07/2003) Unknown status NCT00198991 Phase 4 Cyclophosphamide;Dexamethasone;Vincristine;daunorubicin;Asparaginase;Methotrexate;Cytarabine;Mercaptopurine;G-CSF;Vindesine;VP16;Prednisolone;Adriamycin;Thioguanine;VM26;Idarubicin;Fludarabine;Cladribine
6 Poly(Ethylene Glycol)(PEG)-Asparaginase During Two Treatment Courses Unknown status NCT00192673 Phase 4 PEG-asparaginase
7 HD-Idarubicin/Etoposide Intensified Conditioning Regimen Allo-HSCT for Adult ALL Unknown status NCT01873807 Phase 4 IDA;CTX;VP-16
8 Intensification Therapy of Mature B-ALL, Burkitt and Burkitt Like and Other High Grade Non-Hodgkin's Lymphoma in Adults Unknown status NCT00797810 Phase 4 Rituximab
9 ATG Could Improve the Outcome Of Hematopoietic Stem Cell Transplant in Patients With Highly Aggressive T Cell Tumors Unknown status NCT02290132 Phase 4 Rabbit Anti-human Thymocyte Globulin (ATG)
10 Assessment Of Gh-Igf-1 Axis In Children With Chronic Myelogenous Leukemia (CML) In Remission Unknown status NCT01901666 Phase 4 Growth Hormone
11 Pulses of Vincristine and Dexamethasone in BFM Protocols for Children With Acute Lymphoblastic Leukemia Completed NCT00411541 Phase 4 vincristine;dexamethasone
12 A Study of MabThera Added to Bendamustine or Chlorambucil in Patients With Chronic Lymphocytic Leukemia (MaBLe) Completed NCT01056510 Phase 4 bendamustine;chlorambucil;rituximab [MabThera/Rituxan]
13 Observational Study in Participants With Chronic Lymphocytic Leukemia (CLL), Multiple Myeloma (MM) and Non-Hodgkin's Lymphoma (NHL) in Latin America Completed NCT02559583 Phase 4
14 LAL-AR-N-2005:Study Treatment for Children High Risk Acute Lymphoblastic Leukemia Completed NCT00526409 Phase 4 Prednisolone;Daunorubicin;Vincristine;L-Asparaginase;Cyclophosphamide;Methotrexate;Cytosine Arabinoside
15 PETHEMA LAL-RI/96: Treatment for Patients With Standard Risk Acute Lymphoblastic Leukemia Completed NCT00494897 Phase 4 Asparaginase;Cyclophosphamide;Cytarabine;Daunorubicin;Mercaptopurine;Prednisone;Vincristine;Methotrexate
16 Rituximab Plus Chemotherapy for CD20+ Adult Acute Lymphoblastic Leukemia Completed NCT01358253 Phase 4 Cyclophosphamide;Doxorubicin;Vincristine;Dexamethasone;Cytarabine;Methotrexate;Rituximab;6-Mercaptopurine;Prednisone;L-asparaginase
17 Treatment of Elderly Patients (>65 Years) With Acute Lymphoblastic Leukemia Completed NCT00199095 Phase 4 Adriamycin;Cyclophosphamide;Cytarabine;Dexamethasone;Idarubicin;Ifosfamide;Methotrexate;Mercaptopurine;VM26;Vincristine
18 LAL-Ph-2000: Treatment of Acute Lymphoblastic Leukemia Chromosome Philadelphia Positive Completed NCT00526305 Phase 4 Vincristine;Daunorubicin;Prednisone;L-Asparaginase;Mitoxantrone;Cytosine Arabinoside;Hydrocortisone;Mercaptopurine;Cyclophosphamide;Dexamethasone
19 Antiviral Treatment of Chronic Lymphocytic Leukemia Completed NCT01255644 Phase 4 Valganciclovir
20 A Study of Rituximab in Combination With Fludarabine and Cyclophosphamide in Participants With Chronic Lymphocytic Leukemia and Favorable Somatic Status Completed NCT01271010 Phase 4 Cyclophosphamide;Fludarabine;Rituximab
21 A Study to Compare Mabthera (Rituximab), Fludarabine and Cyclophosphamide to Mabthera and Chlorambucil in Patients With Chronic Lymphocytic Leukemia and Unfavourable Somatic Status Completed NCT01283386 Phase 4 chlorambucil;cyclophosphamide;fludarabine;rituximab [MabThera]
22 ALL-REZ BFM 2002: Multi-Center Study for Children With Relapsed Acute Lymphoblastic Leukemia Completed NCT00114348 Phase 4
23 German Multicenter Trial for Treatment of Newly Diagnosed Acute Lymphoblastic Leukemia in Adults (05/93) Completed NCT00199069 Phase 4 Asparaginase;Vincristine;Daunorubicin, Adriamycin;Cyclophosphamide;Ifosfamide;Cytarabine;Mitoxantrone;Methotrexate;6-Mercaptopurine;6-Thioguanine;VM26;Dexamethasone / Prednisolone
24 German Multicenter Trial for Treatment of Newly Diagnosed Acute Lymphoblastic Leukemia in Adults (06/99) Completed NCT00199056 Phase 4 Dexamethasone / Prednisolone;Cyclophosphamide;Methotrexate;Vincristine / Vindesine;Daunorubicin;Asparaginase;G-CSF;Cytarabine;6-Mercaptopurine;VP16;Adriamycin;Thioguanine;VM26;Idarubicin;Fludarabine;Ifosfamide
25 Trial for Treatment of Adult Patients With Standard Risk Acute Lymphoblastic Leukemia With Chemotherapy and Rituximab Completed NCT00199004 Phase 4 Cyclophosphamide;Dexamethasone / Prednisolone;Vincristine;Daunorubicin;Asparaginase;Methotrexate;Cytarabine;Mercaptopurine;G-CSF;Vindesine;VP16;Adriamycin;Thioguanine;VM26;Rituximab
26 A Study to Confirm the Efficacy and Safety of Fludarabine Phosphate Administered in Untreated Chronic Lymphocytic Leukemia Patients With Anemia and/or Thrombocytopenia Completed NCT00220311 Phase 4 Fludarabine Phosphate (Fludara)
27 Learning Impairments Among Survivors of Childhood Cancer Completed NCT00576472 Phase 4 Methylphenidate
28 Efficacy and Safety of Ofatumumab Retreatment and Maintenance Treatment in Patients With B-cell Chronic Lymphocytic Leukemia (CLL) Completed NCT00802737 Phase 4 Ofatumumab
29 LAL-BR/2001: Study Treatment to Low Risk ALL Completed NCT00526175 Phase 4 Prednisone;Vincristine;Daunorubicin;L-Asparaginase;Cyclophosphamide;Methotrexate;Cytosine Arabinoside;Mercaptopurine;VP-16
30 The Study on the Pharmacokinetics of PEG-rhG-CSF in Children and Adolescents Completed NCT02953730 Phase 4 PEG-rhG-CSF
31 Effect of rhIL-11 in Patients With Thrombocytopenia for Childhood ALL Completed NCT02314273 Phase 4 rhIL-11
32 The Duration of Humoral Immunity and the Memory Cell Function After Vaccination With 7-valent Pneumococcal Conjugate Vaccine in CLL Completed NCT00919321 Phase 4
33 Effect of Epoetin Alfa on Hemoglobin, Symptom Distress, and Quality of Life in Patients Receiving Chemotherapy Completed NCT00524407 Phase 4 Epoetin alfa
34 Trial for the Treatment of Newly Diagnosed Mature B-Cell Acute Lymphoblastic Leukemia (B-ALL), Burkitt's Non-Hodgkin's Lymphoma (NHL) and Other High-grade Lymphoma in Adults Completed NCT00199082 Phase 4 Adriamycin;Cyclophosphamide;Cytarabine;Dexamethasone/Prednisolone;VP16;Ifosfamide;Methotrexate;G-CSF;Rituximab;Vincristine/Vindesine
35 German Multicenter Trial for the Treatment of Newly Diagnosed T-lymphoblastic Lymphoma in Adults Completed NCT00199017 Phase 4 Dexamethasone/Prednisolone;Cyclophosphamide;Vincristine;Daunorubicin;Asparaginase;G-CSF;Mercaptopurine;Cytarabine;Methotrexate;VP16;Vindesine;Adriamycin;Thioguanine;HDARAC;Cladribine
36 Bone Marrow Transplantation in Treating Patients With Hematologic Cancer Completed NCT00003398 Phase 4 cyclophosphamide;thiotepa
37 Identification of New Immune Factors Specific of Relapse in Childhood B Lineage Acute Lymphoblastic Leukemia Recruiting NCT02618109 Phase 4
38 The GD-2008 ALL Protocol for Childhood Acute Lymphoblastic Leukemia Recruiting NCT00846703 Phase 4 6-mercaptopurine, Methotrexate;6-mercaptopurine, Methotrexate, Vincristine, Dexamethasone
39 Protocol For the Treatment Acute Lymphoblastic Leukemia With Ph 'Negative in Elderly Patients (> 55 Years) Recruiting NCT01366898 Phase 4 Dexamethasona, Idarubicine, ARA-C, Methotrexate
40 Treatment of Acute Lymphoblastic Leukemia HIGH RISK BCR / ABL NEGATIVE IN ADULTS Recruiting NCT01540812 Phase 4 Vincristine in induction;Daunorubicin in induction;Prednisone in induction;Metotrexato in induction;Cytarabine in induction;Hydrocortisone in induction;Idarubicin in induction-2;Fludarabine in induction-2;Ara-C in induction-2;G-CSF in induction-2;Dexamethasone in consolidation-1;Vincristrine in consolidation-1;Metotrexato in consolidation-1;PEG-ASP in consolidation-1;Dexamethasone in consolidation-2;ARA-C in consolidation-2;PEG-ASP in consolidation-2;Dexamethasone in consolidation-3;Vincristine in consolidation-3;Metotrexato in consolidation-3;PEG-ASP in consolidation-3
41 Malaysia-Singapore Acute Lymphoblastic Leukemia 2010 Study Recruiting NCT02894645 Phase 4 Prednisolone;Dexamethasone;L-Asparaginase;Vincristine;Methotrexate;Daunorubicin;Doxorubicin;Cyclophosphamide;Cytarabine;6-Mercaptopurine;Thioguanine;Fludarabine;Imatinib
42 Chemotherapy and Imatinib in Young Adults With Acute Lymphoblastic Leukemia Ph (BCR-ABL) POSITIVE Recruiting NCT01491763 Phase 4 Imatinib
43 Study on Two Different Formulations of 6-mercaptopurine. Tablet Versus Oral Liquid Recruiting NCT01906671 Phase 4 Xaluprine;Puri-Nethol
44 PETHEMA LAL-07FRAIL: All Treatment In Fragile Patients Ph' Negative Over 55 Years Recruiting NCT01358201 Phase 4 vINCRISTINE;Dexamethasone;Methotrexate;Cytosine arabinoside
45 Vaccinating Children After Chemotherapy Recruiting NCT02447718 Phase 4
46 ALL SCTped FORUM - Pharmacogenomic Study (add-on Study) Recruiting NCT02670564 Phase 4
47 Pethema LAL-RI/2008: Treatment for Patients With Standard Risk Acute Lymphoblastic Leukemia Recruiting NCT02036489 Phase 4 Vincristine;Daunorubicin;Prednisone;L-asparaginase;Ciclophosphamide;Metotrexate;ARA-C;Hidrocortisone;Mercaptopurine;VP-16;Dexametasone
48 Low Grade Lymphoma Recruiting NCT01698866 Phase 4
49 ATG Based Conditioning Regimen in HLA Related HSCT for Aggressive T-cell Tumors Recruiting NCT02938741 Phase 4 Anti-human Thymoglobulin;Placebo
50 Rituximab (RTX) Therapy in Patients With Active TAO Recruiting NCT02378298 Phase 4 Rituximab;Iv Methylprednisolone;peroral methylprednisolone and Methotrexate

Search NIH Clinical Center for Lymphoid Leukemia

Inferred drug relations via UMLS 69 / NDF-RT 48 :


Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Lymphoid Leukemia cell therapies at LifeMap Discovery.
Stem-cell-based therapeutic approaches for Lymphoid Leukemia:
StemEx
Embryonic/Adult Cultured Cells Related to Lymphoid Leukemia:
Umbilical cord blood stem/progenitor cells (Stemex) PMIDs: 18209724

Genetic Tests for Lymphoid Leukemia

Genetic tests related to Lymphoid Leukemia:

id Genetic test Affiliating Genes
1 Lymphoid Leukemia 29

Anatomical Context for Lymphoid Leukemia

MalaCards organs/tissues related to Lymphoid Leukemia:

39
B Cells, T Cells, Bone, Bone Marrow, Myeloid, Kidney, Nk Cells

Publications for Lymphoid Leukemia

Articles related to Lymphoid Leukemia:

(show top 50) (show all 125)
id Title Authors Year
1
Lipoxygenase Inhibitors Nordihydroguaiaretic Acid and Fungus Lecanicillum lecanii Extract Induce Death of Lymphoid Leukemia Cells. ( 28744653 )
2017
2
Time and spatial trends in lymphoid leukemia and lymphoma incidence and survival among children and adolescents in Manitoba, Canada: 1984-2013. ( 28430788 )
2017
3
Peripheral T-Cell Lymphoma in Mediastinum Lymph Nodes and Lung Associated to Histoplasmosis in a Patient with Chronic Lymphoid Leukemia/Small Lymphocytic Lymphoma. ( 28698787 )
2017
4
KML001 and doxercalciferol induce synergistic antileukemic effect in acute lymphoid leukemia cells. ( 28586017 )
2017
5
Epigenetic drug combination overcomes osteoblast-induced chemoprotection in pediatric acute lymphoid leukemia. ( 28171800 )
2017
6
DNA damage response in patients with pediatric Acute Lymphoid Leukemia during induction therapy. ( 28109975 )
2017
7
Inverse Correlation of Lymphoid Leukemia Incidence and Anemia Prevalence among Preschool Children. ( 28464174 )
2017
8
Incidence of Myelofibrosis in Chronic Myeloid Leukemia, Multiple Myeloma, and Chronic Lymphoid Leukemia during Various Phases of Diseases. ( 28239786 )
2017
9
Extramedullary Relapse of Acute Myeloid and Lymphoid Leukemia in Children: A Retrospective Analysis. ( 27617062 )
2016
10
Specific Antileukemic Activity of PD0332991, a CDK4/6 Inhibitor, against Philadelphia Chromosome-Positive Lymphoid Leukemia. ( 26637365 )
2016
11
Correction: Aberrant Notch Signaling in the Bone Marrow Microenvironment of Acute Lymphoid Leukemia Suppresses Osteoblast-Mediated Support of Hematopoietic Niche Function. ( 27197270 )
2016
12
Leukemia-free survival in myeloid leukemia, but not in lymphoid leukemia, is predicted by early CD4+ reconstitution following unrelated cord blood transplantation in children: a multicenter retrospective cohort analysis. ( 27159172 )
2016
13
Aberrant Notch Signaling in the Bone Marrow Microenvironment of Acute Lymphoid Leukemia Suppresses Osteoblast-Mediated Support of Hematopoietic Niche Function. ( 26801976 )
2016
14
Clonal conversion of B lymphoid leukemia reveals cross-lineage transfer of malignant states. ( 27913602 )
2016
15
E2A-PBX1 Remodels Oncogenic Signaling Networks in B-cell Precursor Acute Lymphoid Leukemia. ( 27758892 )
2016
16
Advanced chronic lymphoid leukemia with severe bronchopneumonia: an Autopsy Case Report. ( 27284536 )
2016
17
Type distribution of lymphoid leukemia from Cancer Incidence in Five Continents Vol. X. ( 26941374 )
2016
18
Synthesis and evaluation of the cytotoxic activity of novel ethyl 4-[4-(4-substitutedpiperidin-1-yl)]benzyl-phenylpyrrolo[1,2-a]quinoxaline-carboxylate derivatives in myeloid and lymphoid leukemia cell lines. ( 26945110 )
2016
19
Invasive fungal diseases in patients with acute lymphoid leukemia. ( 26949001 )
2016
20
Chimeric Antigen Receptor-Modified T Cells in Chronic Lymphoid Leukemia; Chimeric Antigen Receptor-Modified T Cells for Acute Lymphoid Leukemia; Chimeric Antigen Receptor T Cells for Sustained Remissions in Leukemia. ( 26962747 )
2016
21
Non-biased and complete case registration of lymphoid leukemia and lymphoma for five years: a first representative index of Japan from an epidemiologically stable Miyagi Prefecture. ( 27185073 )
2016
22
Growth Inhibition Accompanied by MOB1 Upregulation in Human Acute Lymphoid Leukemia Cells by 3-Deazaneplanocin A. ( 26298709 )
2015
23
Blinatumomab: a bispecific T cell engager (BiTE) antibody against CD19/CD3 for refractory acute lymphoid leukemia. ( 26337639 )
2015
24
Clinico-hematological profile of patients with B-chronic lymphoid leukemia in Pakistan. ( 25684527 )
2015
25
Chemotherapy Exposure and outcomes Among Patients Diagnosed with Chronic Lymphoid Leukemia. ( 26532698 )
2015
26
Serum 25-hydroxyvitamin D Insufficiency in B-Chronic Lymphoid Leukemia at the Time of Disease Presentation in Pakistan. ( 26320484 )
2015
27
Transcription factor networks in B-cell differentiation link development to acute lymphoid leukemia. ( 25990863 )
2015
28
[Association between polymorphism of RAD50 gene and acute lymphoid leukemia in children]. ( 26014697 )
2015
29
Acute oral complications in a pediatric patient with acute lymphoid leukemia. ( 26711327 )
2015
30
Direct Coombs Test Positivity in B-Chronic Lymphoid Leukemia: a Marker of Advanced Clinical Disease. ( 26320488 )
2015
31
Role of Interleukin-10 Gene Promoter Region Polymorphism in the Development of Chronic Lymphoid Leukemia. ( 26642793 )
2015
32
Associations between genetic variants in folate and drug metabolizing pathways and relapse risk in pediatric acute lymphoid leukemia on CCG-1952. ( 26605150 )
2015
33
Neutralization of (NK-cell-derived) B-cell activating factor by Belimumab restores sensitivity of chronic lymphoid leukemia cells to direct and Rituximab-induced NK lysis. ( 25710310 )
2015
34
Panniculitis in Patients Undergoing Treatment With the Bruton Tyrosine Kinase Inhibitor Ibrutinib for Lymphoid Leukemias. ( 26182170 )
2015
35
T-cell acute lymphoid leukemia resembling Burkitt leukemia cell morphology: A case report. ( 25663889 )
2015
36
Phase II Trial of Reduced-Intensity Busulfan/Clofarabine Conditioning with Allogeneic Hematopoietic Stem Cell Transplantation for Patients with Acute Myeloid Leukemia, Myelodysplastic Syndromes, and Acute Lymphoid Leukemia. ( 26260679 )
2015
37
ZAP-70 protein expression in B-cell chronic lymphoid leukemia: a single center experience from Pakistan. ( 25743836 )
2015
38
Changes in the treatment landscape for chronic lymphoid leukemia. ( 25014693 )
2014
39
Endothelial Health in Childhood Acute Lymphoid Leukemia Survivors: Pilot Evaluation With Peripheral Artery Tonometry. ( 24577544 )
2014
40
A Pilot Study for the Detection of FLT3-ITD Mutation Frequency in 25 Iraqi Patients With Acute Lymphoid Leukemia in 2 Iraqi Hospitals. ( 24390456 )
2014
41
Ibrutinib versus ofatumumab in previously treated chronic lymphoid leukemia. ( 24881631 )
2014
42
Clofarabine for the treatment of Adult Acute Lymphoid Leukemia A review article by the GRAALL intergroup. ( 24996442 )
2014
43
Viability and stress protection of chronic lymphoid leukemia cells involves overactivation of mitochondrial phosphoSTAT3Ser727. ( 25299776 )
2014
44
Correlation between FDG/PET, histology, characteristics, and survival in 332 patients with chronic lymphoid leukemia. ( 24615780 )
2014
45
Normalization of lymphocyte count after high ablative dose of I-131 in a patient with chronic lymphoid leukemia and secondary papillary carcinoma of the thyroid. Case report. ( 24728254 )
2014
46
Synthesis and evaluation of the cytotoxic activity of 1,2-furanonaphthoquinones tethered to 1,2,3-1H-triazoles in myeloid and lymphoid leukemia cell lines. ( 25064348 )
2014
47
Acute lymphoid leukemia cells with greater stem cell antigen-1 (Ly6a/Sca-1) expression exhibit higher levels of metalloproteinase activity and are more aggressive in vivo. ( 24586463 )
2014
48
Evaluation of selected honey and one of its phenolic constituent eugenol against L1210 lymphoid leukemia. ( 25506620 )
2014
49
Identification of GPM6A and GPM6B as potential new human lymphoid leukemia-associated oncogenes. ( 24916915 )
2014
50
Differential effects of polyphenols on proliferation and apoptosis in human myeloid and lymphoid leukemia cell lines. ( 23796248 )
2013

Variations for Lymphoid Leukemia

Expression for Lymphoid Leukemia

Search GEO for disease gene expression data for Lymphoid Leukemia.

Pathways for Lymphoid Leukemia

Pathways related to Lymphoid Leukemia according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1 11.93 BCR RUNX1 RUNX1T1
2 11.63 RUNX1 RUNX1T1 ZAP70
3 11.18 ETV6 KMT2A RUNX1 RUNX1T1

GO Terms for Lymphoid Leukemia

Biological processes related to Lymphoid Leukemia according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 definitive hemopoiesis GO:0060216 8.96 BCR KMT2A
2 hematopoietic stem cell proliferation GO:0071425 8.62 ETV6 RUNX1

Molecular functions related to Lymphoid Leukemia according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 protein binding GO:0005515 9.28 BCR CD5 ETV6 KMT2A NCKIPSD RUNX1
2 transcription factor activity, sequence-specific DNA binding GO:0003700 9.26 ETV6 KMT2A RUNX1 RUNX1T1

Sources for Lymphoid Leukemia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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