AGBK
MCID: MCR021
MIFTS: 32

Macrocephaly with Multiple Epiphyseal Dysplasia and Distinctive Facies (AGBK) malady

Categories: Genetic diseases, Bone diseases, Fetal diseases, Rare diseases

Aliases & Classifications for Macrocephaly with Multiple Epiphyseal Dysplasia and Distinctive...

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Aliases & Descriptions for Macrocephaly with Multiple Epiphyseal Dysplasia and Distinctive Facies:

Name: Macrocephaly with Multiple Epiphyseal Dysplasia and Distinctive Facies 52 70 12 68
Multiple Epiphyseal Dysplasia-Macrocephaly-Distinctive Facies Syndrome 54
Multiple Epiphyseal Dysplasia, Al-Gazali Type 54
Al-Gazali-Bakalinova Syndrome 70
 
Craniofacial Abnormalities 39
Mmedf 70
Agbk 70

Characteristics:

Orphanet epidemiological data:

54
multiple epiphyseal dysplasia-macrocephaly-distinctive facies syndrome:
Inheritance: Autosomal recessive; Prevalence: <1/1000000 (Worldwide); Age of onset: Infancy,Neonatal

HPO:

64
macrocephaly with multiple epiphyseal dysplasia and distinctive facies:
Inheritance: autosomal recessive inheritance

Classifications:



External Ids:

OMIM52 607131
Orphanet54 ORPHA166024
ICD10 via Orphanet31 Q77.3
MedGen37 C1846722
ICD1030 Q75.3

Summaries for Macrocephaly with Multiple Epiphyseal Dysplasia and Distinctive...

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UniProtKB/Swiss-Prot:70 Al-Gazali-Bakalinova syndrome: An autosomal recessive syndrome consisting of macrocephaly, multiple epiphyseal dysplasia and distinctive facial appearance.

MalaCards based summary: Macrocephaly with Multiple Epiphyseal Dysplasia and Distinctive Facies, also known as multiple epiphyseal dysplasia-macrocephaly-distinctive facies syndrome, is related to craniofacial abnormalities, cataracts, congenital heart disease, sacral neural tube defects, and growth and developmental retardation and x-linked mental retardation craniofacial abnormal microcephaly club, and has symptoms including Array, Array and Array. An important gene associated with Macrocephaly with Multiple Epiphyseal Dysplasia and Distinctive Facies is KIF7 (Kinesin Family Member 7). Affiliated tissues include brain and bone.

Description from OMIM:52 607131

Related Diseases for Macrocephaly with Multiple Epiphyseal Dysplasia and Distinctive...

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Diseases related to Macrocephaly with Multiple Epiphyseal Dysplasia and Distinctive Facies via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 58)
idRelated DiseaseScoreTop Affiliating Genes
1craniofacial abnormalities, cataracts, congenital heart disease, sacral neural tube defects, and growth and developmental retardation11.9
2x-linked mental retardation craniofacial abnormal microcephaly club11.9
3immunodeficiency 4911.5
4distal arthrogryposis11.2
5opsismodysplasia10.8
6arthrogryposis, distal, type 2b10.8
7larsen syndrome10.8
8peroxisome biogenesis disorder 1a10.7
9ritscher-schinzel syndrome10.7
10short stature, auditory canal atresia, mandibular hypoplasia, skeletal abnormalities10.7
11peroxisome biogenesis disorder 6a10.5
12peroxisome biogenesis disorder 13a10.5
13hirschsprung disease, cardiac defects, and autonomic dysfunction10.5
14peroxisome biogenesis disorder 12a10.5
15peroxisome biogenesis disorder 11a10.5
16fetal akinesia deformation sequence10.5
17peroxisome biogenesis disorder 4a10.5
18peroxisome biogenesis disorder 10a10.5
19saethre-chotzen syndrome10.5
20jackson-weiss syndrome10.5
21osteoglophonic dysplasia10.5
22peroxisome biogenesis disorder 5a10.5
23peroxisome biogenesis disorder 8a,10.5
24potocki-shaffer syndrome10.5
25peroxisome biogenesis disorder 2a10.5
26stickler sydrome, type i, nonsyndromic ocular10.5
27acrocallosal syndrome10.5
28rubinstein-taybi syndrome10.5
29peroxisome biogenesis disorder 3a10.5
30peroxisome biogenesis disorder 7a10.5
31rubinstein-taybi syndrome 210.5
32gomez-lopez-hernandez syndrome10.5
33antley-bixler syndrome10.5
34robinow syndrome10.5
35ritscher-schinzel syndrome 210.5
36arrhinia10.5
37encephalocele10.5
38multiple epiphyseal dysplasia10.3
39arthrogryposis, renal dysfunction, and cholestasis 19.8KIF7, MMEDF
40cleidocranial dysplasia9.7
41hutchinson-gilford progeria9.5
42cryptorchidism9.5
43lujan-fryns syndrome9.5
44kearns-sayre syndrome9.5
45macroglossia9.5
46fryns syndrome9.5
47holoprosencephaly9.5
48congenital fiber-type disproportion9.5
49mucopolysaccharidosis9.5
50progeria9.5

Graphical network of the top 20 diseases related to Macrocephaly with Multiple Epiphyseal Dysplasia and Distinctive Facies:



Diseases related to macrocephaly with multiple epiphyseal dysplasia and distinctive facies

Symptoms & Phenotypes for Macrocephaly with Multiple Epiphyseal Dysplasia and Distinctive...

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Symptoms by clinical synopsis from OMIM:

607131

Clinical features from OMIM:

607131

Human phenotypes related to Macrocephaly with Multiple Epiphyseal Dysplasia and Distinctive Facies:

 54 64 (show all 21)
id Description HPO Frequency Orphanet Frequency HPO Source Accession
1 macrocephaly64 54 Very frequent (99-80%) HP:0000256
2 malar flattening64 54 Very frequent (99-80%) HP:0000272
3 hypertelorism64 54 Very frequent (99-80%) HP:0000316
4 low-set ears64 54 Very frequent (99-80%) HP:0000369
5 short neck64 54 Very frequent (99-80%) HP:0000470
6 pectus excavatum64 54 Very frequent (99-80%) HP:0000767
7 agenesis of corpus callosum64 54 Frequent (79-30%) HP:0001274
8 joint dislocation64 54 Very frequent (99-80%) HP:0001373
9 obesity64 54 Frequent (79-30%) HP:0001513
10 frontal bossing64 54 Very frequent (99-80%) HP:0002007
11 osteoarthritis64 54 Very frequent (99-80%) HP:0002758
12 genu valgum64 54 Very frequent (99-80%) HP:0002857
13 abnormality of epiphysis morphology64 54 Very frequent (99-80%) HP:0005930
14 finger syndactyly64 54 Very frequent (99-80%) HP:0006101
15 brain atrophy64 54 Frequent (79-30%) HP:0012444
16 clinodactyly64 54 Very frequent (99-80%) HP:0030084
17 inguinal hernia64 HP:0000023
18 pectus carinatum64 HP:0000768
19 lymphedema64 HP:0001004
20 abnormal facial shape64 HP:0001999
21 multiple epiphyseal dysplasia64 HP:0002654

Drugs & Therapeutics for Macrocephaly with Multiple Epiphyseal Dysplasia and Distinctive...

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Drugs for Macrocephaly with Multiple Epiphyseal Dysplasia and Distinctive Facies (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 198)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Tranexamic AcidapprovedPhase 4, Phase 32771197-18-85526
Synonyms:
08455_FLUKA
1197-17-7
1197-18-8
1ceb
3-14-00-00868 (Beilstein Handbook Reference)
4-(Aminomethyl)-Cyclohexanecarboxylic Acid
4-(Aminomethyl)cyclohexanecarboxylic acid
4-(aminomethyl)cyclohexane-1-carboxylic acid
857653_ALDRICH
A0236
AB00052260
AB1003647
AC-4687
AC1L1KJH
AC1Q50F3
AC1Q546D
AC1Q5U04
ALBB-006013
AMCA
AMCHA
AMH
AR-1F6595
Acide tranexamique
Acide tranexamique [INN-French]
Acido tranexamico
Acido tranexamico [INN-Spanish]
Acidum tranexamicum
Acidum tranexamicum [INN-Latin]
Amikapron
Amstat
Anvitoff
BAY 3517
BPBio1_000069
BRN 2207452
BSPBio_000061
BSPBio_002837
CAS-1197-18-8
CHEBI:48669
CHEMBL292500
CHEMBL877
CID5526
CL 65336
CL-65336
Carxamin
Cyclocapron
Cyklokapron
Cyklokapron (TN)
D01136
DB00302
DV 79
DV-79
DV79
DivK1c_000655
EINECS 214-818-2
Emorhalt
Exacyl
Frenolyse
HMS1568D03
HMS1921F08
HMS2092P03
HMS502A17
Hexapromin
Hexatron
I04-0993
IDI1_000655
KABI 2161
KBio1_000655
KBio2_001871
KBio2_004439
KBio2_007007
KBio3_002337
KBioGR_000511
 
KBioSS_001871
LS-56611
LS-56612
LT00159441
Mastop
MolPort-001-792-390
MolPort-002-512-008
NCGC00016569-01
NCGC00016569-02
NCGC00016569-03
NCGC00094944-01
NCGC00094944-02
NINDS_000655
NSC 291305
NSC291305
Oprea1_786414
Prestwick0_000171
Prestwick1_000171
Prestwick2_000171
Prestwick3_000171
Prestwick_476
RP 18,429
Rikavarin
Rikavarin (TN)
Rikavarin-S
SPBio_000689
SPBio_001982
SPECTRUM1502026
STK503668
STOCK1N-16183
Spectrum2_000655
Spectrum3_001189
Spectrum4_000046
Spectrum5_001258
Spectrum_001391
Spiramin
Tamcha
Tranex
Tranexamate
Tranexamic acid (JP15/USAN/INN)
Tranexamic acid [USAN:INN:BAN:JAN]
Tranexamic acid cis-form
Tranexamsaeure
Tranexan
Tranexmic acid
Tranhexamic acid
Trans AMCHA
Trans-1-(Aminomethyl)cyclohexane-4-carboxylic acid
Trans-4-(Aminomethyl)-1-cyclohexanecarboxylic acid
Trans-p-(Aminomethyl)cyclohexanecarboxylic
Transamin
Transamin (TN)
Transamlon
Trasamlon
UNII-6T84R30KC1
Ugurol
WLN: L6TJ AVQ D1Z -T
cis-4-(Aminomethyl)cyclohexanecarboxylic acid
cis-4-Aminomethylcyclohexane-1-carboxylic acid
cis-AMCHA
t-AMCHA
tranexamic acid
tranexmic acid
trans-1-Aminomethylcyclohexane-4-carboxylic acid
trans-4-(Aminomethyl)cyclohexane-1-carboxylic acid
trans-4-(Aminomethyl)cyclohexane-carboxylic acid
trans-4-(Aminomethyl)cyclohexanecarboxylic acid
trans-4-(Aminomethyl)cyclohexanecarboxylic acid ester
trans-4-Aminomethylcyclohexane-1-carboxylic acid
trans-4-aminomethylcyclohexane-1-carboxylic acid
trans-Amcha
trans-Tranexamic acid
trans-p-(Aminomethyl)cyclohexanecarboxylic acid
2
OxcarbazepineapprovedPhase 45628721-07-534312
Synonyms:
10,11-Dihydro-10-oxo-5H-debenz(b,f)azepine-5-carboxamide
10,11-Dihydro-10-oxo-5H-dibenz(b,F)azepine-5-carboxamide
10,11-Dihydro-10-oxo-5H-dibenz(b,f)azepine-5-carboxamide
10,11-Dihydro-10-oxo-5H-dibenzo[b,f]azepine-5-carboxamide
10,11-Dihydro-10-oxo-5h-dibenz[b,f]azepine-5-carboxamide
10-Oxo-10,11-dihydro-5H-dibenzo[b,f]azepine-5-carboxamide
28721-07-5
5-oxo-6H-benzo[b][1]benzazepine-11-carboxamide
AB1004555
AC-3483
AC1L1RCU
AC1Q6NA8
BIDD:GT0078
BSPBio_003457
Bio-0527
C036006
C07492
CHEMBL1068
CID34312
CPD000048684
D00533
DB00776
Desitin brand of oxcarbazepine
EINECS 249-188-8
Epilexter
Epliga
GP 47680
GP-47680
HMS1922H17
HMS2051O04
HMS2090F13
HMS2093E10
HSDB 7524
I06-0072
KBio2_002155
KBio2_004723
KBio2_007291
KBio3_002677
KBioGR_001248
KBioSS_002155
 
KIN-493
LS-60365
MLS000084586
MLS000759520
MLS001201742
MolPort-001-685-316
NCGC00065934-02
NCGC00065934-03
NCGC00065934-04
Novartis brand of oxcarbazepine
O0363
O3764_SIGMA
OCBZ
OXCARBAZEPINE
Oxacarbazepine
Oxcarbamazepine
Oxcarbazepime
Oxcarbazepina
Oxcarbazepina [INN-Spanish]
Oxcarbazepine
Oxcarbazepine (USAN/INN)
Oxcarbazepine [INN]
Oxcarbazepinum
Oxcarbazepinum [INN-Latin]
S1391_Selleck
SAM001246754
SMR000048684
SPBio_000345
SPECTRUM1504243
SPN-804
STK594696
Spectrum2_000483
Spectrum3_001669
Spectrum4_000634
Spectrum5_001869
Spectrum_001675
Timox
Trileptal
Trileptal (TN)
UNII-VZI5B1W380
ZINC00004724
oxcarbazepine
3
NicardipineapprovedPhase 43155985-32-54474
Synonyms:
2-(Benzylmethylamino)ethyl methyl 1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)pyridine-3,5-dicarboxylate
3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 2-(benzylmethylamino)ethyl methyl ester
3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, methyl 2-(methyl(phenylmethyl)amino)ethyl ester
3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, methyl 2-[methyl(phenylmethyl)amino]ethyl ester
3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-,2-(benzylmethylamino)ethyl methyl ester
5-O-[2-[benzyl(methyl)amino]ethyl] 3-O-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
55985-32-5
AB00514658
AC-19947
AC1L1I8Y
AKOS001637090
Ambap55985-32-5
BIDD:GT0621
BPBio1_000623
BRD-A26711594-001-02-7
BRD-A26711594-003-05-6
BRN 0504321
BSPBio_000565
BSPBio_001389
BSPBio_002943
Bio1_000088
Bio1_000577
Bio1_001066
Bio2_000109
Bio2_000589
C07264
C26H29N3O6
CBiol_001802
CHEBI:507549
CHEMBL1484
CID4474
Cardene
Cardene (TN)
Cardene IV
D08270
DB00622
DivK1c_000540
EINECS 259-932-3
HMS1791F11
HMS1989F11
HMS2089C09
IDI1_000540
IDI1_033859
KBio1_000540
 
KBio2_000109
KBio2_001852
KBio2_002677
KBio2_004420
KBio2_005245
KBio2_006988
KBio3_000217
KBio3_000218
KBio3_002443
KBioGR_000109
KBioGR_000744
KBioSS_000109
KBioSS_001852
L000715
LS-131263
Lopac0_000809
MolPort-002-484-049
NCGC00015747-06
NCGC00162262-01
NCGC00162262-02
NCGC00162262-03
NCGC00162262-04
NINDS_000540
Nicardipine (INN)
Nicardipine LA
Nicardipine [INN:BAN]
Nicardipino
Nicardipino [INN-Spanish]
Nicardipinum
Nicardipinum [INN-Latin]
Oprea1_436998
Prestwick0_000383
Prestwick1_000383
Prestwick2_000383
Prestwick3_000383
SPBio_001490
SPBio_002486
Spectrum2_001415
Spectrum3_001452
Spectrum4_000422
Spectrum5_001320
Spectrum_001372
UNII-CZ5312222S
Y-93
methyl 2-[methyl(phenylmethyl)amino]ethyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
nicardipine
4
Carbamazepineapproved, investigationalPhase 4132298-46-42554
Synonyms:
2-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8),4,6,9,12,14-heptaene-2-carboxamide
298-46-4
5-Carbamoyl-5H-dibenz(b,f)azepine
5-Carbamoyl-5H-dibenz[b,F]azepine
5-Carbamoyl-5H-dibenz[b,f]azepine
5-Carbamoyl-5H-dibenzo(b,F)azepine
5-Carbamoyl-5H-dibenzo(b,f)azepine
5-Carbamoyldibenzo(b,f)azepine
5-Carbamyl-5H-dibenzo(b,F)azepine
5-Carbamyl-5H-dibenzo(b,f)azepine
5-Carbamyldibenzo(b,f)azepine
5H-Dibenz(b,F)azepine-5-carboxamide
5H-Dibenz(b,f)azepine-5-carboxamide
5H-Dibenz[b,f]azepine-5- carboxamide
5H-Dibenz[b,f]azepine-5-carboxamide
5H-Dibenzo[b,f]azepine-5-carboxamide
85756-57-6 (di-hydrate)
AC-10560
AC1L1DXT
AC1Q4ZSU
AC1Q4ZSV
AKOS003235644
Amizepin
Amizepine
Apo-Carbamazepine
Atretol
BIDD:GT0479
BIM-0050280.0001
BPBio1_000225
BRD-K71799949-001-06-7
BRN 1246090
BSPBio_000203
BSPBio_001929
Bio-0751
Bipotrol
Biston
C 4024
C06868
C4024_SIAL
C4024_SIGMA
C8981_SIAL
CARBAMAZEPINE, U.S.P.
CAS-298-46-4
CBChromo1_000350
CBZ
CDS1_002710
CHEBI:3387
CHEMBL108
CID2554
CPD001227191
Calepsin
Carbamazepan
Carbamazepen
Carbamazepin
Carbamazepina
Carbamazepina [INN-Spanish]
Carbamazepine (JP15/USP/INN)
Carbamazepine [USAN:INN:BAN:JAN]
Carbamazepinum
Carbamazepinum [INN-Latin]
Carbamazépine
Carbamezepine
Carbatrol
Carbatrol extended-release
Carbazepin
Carbazepine
Carbelan
ChemDiv1_018966
D00252
DB00564
DivK1c_000388
DivK1c_003750
EINECS 206-062-7
EU-0100292
Epitol
Epitol, Equetro, Tegretol, Biston, Calepsin, Carbamazepine
Equetro
Equetro (TN)
Finlepsin
G 32883
G-32883
Geigy 32883
HMS1568K05
 
HMS1920I17
HMS2090M07
HMS2091O19
HMS501D10
HMS640O02
HSDB 3019
I06-0863
IDI1_000388
KBio1_000388
KBio2_000516
KBio2_003084
KBio2_005652
KBio3_001149
KBioGR_000724
KBioSS_000516
Karbamazepin
LS-60362
Lexin
Lopac-C-4024
Lopac0_000292
MLS000069652
MLS001055475
MLS001074172
MolPort-000-710-574
NCGC00015234-01
NCGC00015234-02
NCGC00015234-03
NCGC00015234-07
NCGC00015234-13
NCGC00023877-03
NCGC00023877-04
NCGC00023877-05
NCGC00023877-06
NCGC00023877-07
NCGC00023877-08
NINDS_000388
NSC 169864
NSC169864
Neurotol
Neurotop retard
Novo-Carbamaz
Nu-Carbamazepine
Oprea1_790775
Prestwick0_000052
Prestwick1_000052
Prestwick2_000052
Prestwick3_000052
Prestwick_104
S1693_Selleck
SAM002264603
SMR000058201
SMR001227191
SPBio_000170
SPBio_002124
SPD-417
SPECTRUM1500159
STK177357
Sirtal
Spectrum2_000125
Spectrum3_000325
Spectrum4_000262
Spectrum5_000936
Spectrum_000096
Stazepin
Stazepine
Taro-Carbamazepine
Taro-Carbamazepine Cr
Tegretal
Tegretol
Tegretol (TN)
Tegretol Chewtabs
Tegretol Cr
Tegretol-Xr
Telesmin
Teril
Timonil
Trimonil
UNII-33CM23913M
WLN: T C676 BNJ BVZ
ZINC00004785
benzo[b][1]benzazepine-11-carboxamide
carbamazepine
carbamazepine (Tegretol)
nchem.859-comp7
5
Sevofluraneapproved, vet_approvedPhase 450828523-86-65206
Synonyms:
1,1,1,3,3,3-Hexafluoro-2-(fluoromethoxy)propane
28523-86-6
AC-15484
AC1L1JU0
BRN 2041023
Bax 3084
C009250
C07520
C4H3F7O
CHEBI:9130
CHEMBL1200694
CID5206
D00547
DB01236
F0691
Fluoromethyl 1,1,1,3,3,3-Hexafluoroisopropyl Ether
Fluoromethyl 2,2,2-trifluoro-1-(trifluoromethyl)ethyl ether
I14-13357
LS-67851
MR6S4
 
MR_6S4
MolPort-001-775-746
NCGC00167421-01
PC4681
Sevofluran
Sevoflurane
Sevoflurane (JAN/USAN/INN)
Sevoflurane [USAN:INN:BAN:JAN]
Sevoflurano
Sevoflurano [INN-Spanish]
Sevofluranum
Sevofluranum [INN-Latin]
Sevofrane
Sevorane
Sojourn
UNII-38LVP0K73A
Ultane
Ultane (TN)
ZINC01530810
fluoromethyl hexafluoroisopropyl ether
fluoromethyl-2,2,2-trifluoro-1-(trifluoromethyl)ethyl ether
sevoflurane
6
Dexmedetomidineapproved, vet_approvedPhase 459276631-46-4, 113775-47-668602, 5311068, 56032
Synonyms:
(+)-4-((S)-alpha,2,3-Trimethylbenzyl)imidazole
(+)-4-((S)-alpha,2,3-trimethylbenzyl)imidazole
(+)-medetomidine
(S)-medetomidine
113775-47-6
4-[(1S)-1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole
4-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole
5-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole
AC1NSJXT
C07450
CHEBI:4466
CHEMBL778
CID5311068
D00514
DEXMEDETOMIDINE
 
Dexdor (T)
Dexmedetomidin
Dexmedetomidina
Dexmedetomidine
Dexmedetomidine (USAN/INN)
Dexmedetomidinum
Dexmédétomidine
MPV 1440
MPV-1440
Medetomidina [Spanish]
Medetomidine
Medetomidinum [Latin]
NCGC00025347-01
PRECEDEX
Precedex (TN)
Tocris-2023
ZINC04632106
7
RemifentanilapprovedPhase 4471132875-61-760815
Synonyms:
1-Piperidinepropanoic acid, 4-(methoxy-carbonyl)-4-((1-oxopropyl)phenylamino)-, methyl ester
132539-07-2 (mono-hydrochloride)
132875-61-7
3-(4-methoxycarbonyl-4-((1-oxopropyl)phenylamino)-1-piperidine)propanoic acid methyl ester
4-carboxy-4-(n-phenylpropionamido)-1-piperidinepropionic acid dimethyl ester
AC1L1TZ8
AC1Q5ZGR
BIDD:GT0029
C08021
CHEBI:8802
CHEMBL1005
CID60815
D08473
DB00899
 
DEA No. 9739
GI 87084B
GI 87084X
GI87084B
L001266
LS-115982
MolPort-004-286-006
REMIFENTANIL
Remifentanil (INN)
Remifentanil [INN:BAN]
Remifentanyl
UNII-P10582JYYK
Ultiva
Ultiva (TN)
methyl 1-(3-methoxy-3-oxopropyl)-4-(N-propanoylanilino)piperidine-4-carboxylate
8
Codeineapproved, illicitPhase 47776-57-35284371
Synonyms:
(-)-Codeine
(5alpha,6alpha)-17-methyl-3-(methyloxy)-7,8-didehydro-4,5-epoxymorphinan-6-ol
(5alpha,6alpha)-7,8-Didehydro-4,5-epoxy-3-methoxy-17-methylmorphinan-6-ol
(5α,6α)-7,8-didehydro-4,5-epoxy-3-methoxy-17-methylmorphinan-6-ol
(6alpha,13alpha)-3-methoxy-17-methyl-7,8-didehydro-4,5-epoxymorphinan-6-ol
(−)-Codeine
3-Methylmorphin
3-methoxy-17-methyl-7,8-didehydro-4,5alpha-epoxymorphinan-6alpha-ol
3-methylmorphine
3-o-methylmorphine monohydrate
41444-62-6 (PO4)
7,8-Didehydro-4,5-epoxy-3-methoxy-17-methylmorphinan-6-ol
7,8-didehydro-4,5-alpha-epoxy-3-methoxy-17-methylmorphinan-6-alpha-ol
7,8-didehydro-4,5-ep oxy-3-methoxy-17-methylmorphinan-6-ol
7,8-didehydro-4,5-epoxy-3-methoxy-17-methyl-(5alpha, 6alpha)-morphinan 6-ol
7,8-didehydro-4,5alpha-epoxy-3-methoxy-17-methylmorphinan-6alpha-ol
7,8-didehydro-4,5α-epoxy-3-methoxy-17-methylmorphinan-6α-ol
76-57-3
AC-11114
AC1Q4DTD
Actacode
Ardinex
C06174
C1653_FLUKA
C1653_SIGMA
C5901_FLUKA
C5901_SIGMA
CCRIS 7555
CHEBI:16714
CHEMBL485
CID5284371
CODEINE (SEE ALSO: CODEINE PHOSPHATE (CAS 52-28-8))
CODEINE BASE
Calcidrine
Codalgin Forte Codate
Codein
Codeine
Codeine (anhydrous)
Codeine [BAN]
Codeine anhydrous
Codeine solution
 
Codeinum
Codeína
Codicept
Coducept
Codéine
DB00318
EINECS 200-969-1
HSDB 3043
Isocodeine
L-Codeine
LS-1695
Methylmorphine
MolPort-002-506-913
Morphinan-6-ol, 7,8-didehydro-4,5-epoxy-3-methoxy-17-methyl-, (5-alpha,6-alpha)- (9CI)
Morphinan-6-ol, 7,8-didehydro-4,5-epoxy-3-methoxy-17-methyl-, (5alpha,6alpha)- (9CI)
Morphinan-6alpha-ol, 7,8-didehydro-4,5alpha-epoxy-3-methoxy-17-methyl- (8CI)
Morphine 3-methyl ether
Morphine monomethyl ether
Morphine-3-methyl ester
Morphine-3-methyl ether
N-Methylmorphine
N-methyl norcodine
N-methylnorcodeine
Norcodeine, N-Methyl
Norcodeine, N-methyl
Norcodine, N-Methyl
Norcodine, N-methyl
Novahistine DH
O(3)-methylmorphine
O3-Methylmorphine
Robitussin AC
STOCK1N-42851
codeina
codeine
codeinum
l-Codeine
metilmorfina
morphine 3-methyl ether
morphine monomethy l ether
morphine monomethyl ether
morphine-3-methyl ether
nchembio.317-comp2
9
Guaifenesinapproved, vet_approvedPhase 464193-14-13516
Synonyms:
3-(2-Methoxyphenoxy)-1,2-propanediol
3-(O-Methoxyphenoxy)-1,2-propanediol
3-(O-Methoxyphenoxy)-propanediol-1,2
3-O-Methoxyphenoxypropane 1:2-diol
Actifed C
Aeronesin
Amonidren
Amonidrin
Aresol
Benylin-E
Bronchol
Glycerin ether
Glycerin guaiacolate
Glycero-guaiacol ether
Glycerol a-(2-methoxyphenyl) ether
Glycerol a-(O-methoxyphenyl)ether
Glycerol a-guaiacyl ether
Glycerol a-guiacyl ether
Glycerol a-monoguaiacol ether
Glycerol guaiacolate
Glycerol mono(2-methoxyphenyl) ether
Glycerol-a-guajakolether
Glycerol-alpha-guajakolether
Glyceryl guaiacol
Glyceryl guaiacol ether
Glyceryl guaiacolate
Glyceryl guaiacolate ether
Glyceryl guaiacyl ether
Glyceryl guaicolate
Glyceryl guiacolate
 
Glycerylguaiacol
Guaiacol glycerol ether
Guaiacol glyceryl ether
Guaiacolglicerinetere
Guaiacuran
Guaiacurane
Guaiacyl glyceryl ether
Guaiamar
Guaianesin
Guaicol glycerine ether
Guaicol glyceryl ether
Guaifenesin
Guaifenesine
Guaiphenesin
Guaiphenesine
Guaiphesin
Hustosil
Methoxypropanediol
Methphenoxydiol
Metossipropandiolo
O-Methoxyphenyl glyceryl ether
Organidin NR
Pneumomist
Propanosedyl
Reduton
Robitussin
a-Glyceryl guaiacol ether
a-Glyceryl guaiacolate ether
alpha-Glyceryl guaiacol ether
alpha-Glyceryl guaiacolate ether
guaiphenesin
p-Cresyl acetate
10
Celiprololapproved, investigationalPhase 4256980-93-9
Synonyms:
 
RS)-N'-{3-acetyl-4-[3-(tert-butylamino)-2-hydroxypropoxy]phenyl}-N,N-diethylurea
11
Amoxicillinapproved, vet_approvedPhase 446526787-78-033613, 2171
Synonyms:
(-)-6-(2-Amino-2-(P-hydroxyphenyl)acetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo-(3.2.0)heptane-2-carboxylic acid
(2S,5R,6R)-6-[[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
(2S,5R,6R)-6-{[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
26787-78-0
33911-69-2
34642-77-8 (mono-hydrochloride salt)
4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-(2-amino-2-(p-hydroxyphenyl)acetamido)-3,3-dimethyl-7-oxo-, D- (8CI)
6-(D-(-)-alpha-Amino-p-hydroxyphenylacetamido)penicillanic acid
6-(D-(-)-p-Hydroxy-alpha-aminobenzyl)penicillin
6-(a-Amino-4-hydroxyphenylacetamido)penicillanic acid
6-(p-Hydroxy-alpha-aminophenylacetamido)penicillanic acid
6-(p-hydroxy-α-aminophenylacetamido)penicillanic acid
6-[[Amino(4-hydroxyphenyl)acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 9CI
61336-70-7 (TRIHYDRATE)
6beta-[(2R)-2-amino-2-(4-hydroxyphenyl)acetamido]-2,2-dimethylpenam-3alpha-carbonyl
6beta-[(2R)-2-amino-2-(4-hydroxyphenyl)acetamido]-2,2-dimethylpenam-3alpha-carboxylic acid
71447-36-4
81030-75-3
AC-12263
AC1L1PY2
AMC
AMOXICILLIN CRYSTALLINE
AMOXICILLIN PEDIATRIC
AMPC
AUGMENTIN '125'
AUGMENTIN '200'
AUGMENTIN '250'
AUGMENTIN '400'
AUGMENTIN '500'
AUGMENTIN '875'
AUGMENTIN ES-600
AX
Actimoxi
Almodan
Ambap26787-78-0
Amix
Amoclen
Amolin
Amopen
Amopenixin
Amoram
Amox
Amox 250 Cap 250mg
Amox 500 Cap 500mg
Amox S 125 Sus 125mg/5ml
Amox S 250 Sus 250mg/5ml
Amoxi
Amoxi-Mast
Amoxi-mast
Amoxibiotic
Amoxicaps
Amoxicilina
Amoxicilina [INN-Spanish]
Amoxicillin (INN)
Amoxicillin (TN)
Amoxicillin (anhydrous)
Amoxicillin (inn)
Amoxicillin Trihydrate
Amoxicillin and clavulanate potassium
Amoxicillin anhydrous
Amoxicillin pediatric
Amoxicillin trihydrate
Amoxicillin(usan)
Amoxicilline
Amoxicilline [INN-French]
Amoxicilline [INN]
Amoxicilline [inn]
Amoxicillinum
Amoxicillinum [INN-Latin]
Amoxid
Amoxiden
Amoxil
Amoxivet
Amoxycillin
Amoxycillin Trihydrate
Amoxycillin trihydrate
Amoxycillin, BAN
Amoxymed
Amrit
Anemolin
Apo-Amoxi
Apo-Amoxi Cap 250mg
Apo-Amoxi Cap 500mg
Apo-Amoxi Pwr for Susp 125mg/5ml
Apo-Amoxi Pwr for Susp 250mg/5ml
Apo-amoxi
Apo-amoxi sugar free
Aspenil
BL-P 1410
BLP 1410
BPBio1_000499
BRD-K55044200-001-03-9
BRL 2333
BRL-2333
BSPBio_000453
 
Biomox
Bristamox
C06827
CHEBI:2676
CHEBI:53712
CHEMBL1082
CID33613
CPD000058707
Cemoxin
Clamoxyl
Clamoxyl (SKB)
D-(-)-alpha-Amino-p-hydroxybenzyl penicillin
D-(-)-alpha-Amino-p-hydroxybenzylpenicillin
D-(alpha-Amino-p-hydroxybenzyl)penicillin
D-2-Amino-2-(4-hydroxyphenyl)acetamidopenicillanic acid
D-Amoxicillin
D07452
DB01060
Delacillin
DisperMox
Dispermox
EINECS 248-003-8
Efpenix
Flemoxin
Galenamox
Gen-Amoxicillin 250mg
Gen-Amoxicillin 500mg
HMS1569G15
HSDB 3204
Hiconcil
Histocillin
Hydroxyampicillin
Ibiamox
Imacillin
LS-149721
Lamoxy
Larotid
MLS000028632
MLS002222248
Metafarma capsules
Metifarma capsules
MolPort-003-981-182
MolPort-005-933-687
Moxacin
Moxal
Moxatag
NCGC00179554-01
NSC 277174
NSC277174
Novamoxin Cap 250mg
Novamoxin Cap 500mg
Novamoxin Sus 125mg/5ml
Novamoxin Sus 250mg/5ml
Nu-Amoxi Cap 250mg
Nu-Amoxi Cap 500mg
Nu-Amoxi Sus 125/5ml
Nu-Amoxi Sus 250mg/5ml
Ospamox
P-Hydroxyampicillin
PHL-amoxicillin
PMS-amoxicillin
Pamoxicillin
Piramox
Polymox
Prestwick0_000357
Prestwick1_000357
Prestwick2_000357
Prestwick3_000357
Prestwick_713
Prevpac
Pro Amox Pwr for Oral Susp 125mg/5ml
Pro Amox-250 Cap 250mg
Pro Amox-500 Cap 500mg
Pro-Amox-250 Orl Sus 250mg/5ml
R-Hydroxyampicillin
Rimoxallin
Ro 10-8756
Robamox
SAM002264592
SMR000058707
SPBio_002374
Sauracillin
Sawamox PM
Sumox
Tolodina
Trimox
Unicillin
Utimox
Vetramox
Wymox
Zimox
alpha-Amino-p-hydroxybenzylpenicillin
amoxicillanyl
amoxicillin
p-Hydroxyampicillin
α-amino-p-hydroxybenzylpenicillin
12
Methylphenidateapproved, investigationalPhase 4375113-45-14158
Synonyms:
.alpha.-Phenyl-2-piperidineacetic acid methyl ester
113-45-1
2-Piperidineacetic acid, .alpha.-phenyl-, methyl ester
2-Piperidineacetic acid, alpha-phenyl-, methyl ester
298-59-9 (hydrochloride)
4311/B Ciba
AC1L1HJM
C 4311
C07196
CHEBI:6887
CHEMBL796
CID4158
Calocain
Centedein
Centedrin
Centedrine
Centredin
Concerta
D-Methylphenidate HCl
D04999
DB00422
DB06701
DEA No. 1724
Daytrana
Daytrana (TN)
EINECS 204-028-6
Focalin
Focalin XR
HSDB 3126
L001307
LS-565
METHYLPHENIDATE (SEE ALSO: METHYLPHENIDATE HYDROCHLORIDE, CAS 298-59-9, NTPNO 10266-R)
MPH
Meridil
Metadate
Metadate CD
Metadate ER
MethyPatch
Methyl (2-phenyl-2-(2-piperidyl)acetate)
Methyl alpha-phenyl-alpha-(2-piperidyl)acetate
Methyl alpha-phenyl-alpha-2-piperidinylacetate
Methyl phenidate
 
Methyl phenidyl acetate
Methyl phenidylacetate
Methylfenidan
Methylin
Methylin ER
Methylofenidan
Methylphen
Methylphenidan
Methylphenidate
Methylphenidate (USAN/INN)
Methylphenidate HCl
Methylphenidate [INN:BAN]
Methylphenidate hydrochloride
Methylphenidatum
Methylphenidatum [INN-Latin]
Methylphenidylacetate hydrochloride
Methypatch
Metilfenidat hydrochloride
Metilfenidato
Metilfenidato [INN-Spanish]
Metilfenidato [Italian]
MolPort-001-779-620
NCI-C56280
PMS-Methylphenidate
Phenidylate
Plimasine
Riphenidate
Ritalin
Ritalin LA
Ritalin SR
Ritalin hydrochloride
Ritalin-SR
Ritaline
Ritcher Works
Ritcher works
Tsentedrin
UNII-207ZZ9QZ49
alpha-Phenyl-2-piperidineacetic acid methyl ester
alpha-Phenyl-alpha-(2-piperidyl)acetic acid methyl ester
d-methylphenidate HCl
methyl 2-phenyl-2-piperidin-2-ylacetate
methyl phenyl(piperidin-2-yl)acetate
methylphenidate
nchembio.2007.55-comp28
13
DopamineapprovedPhase 4383651-61-6, 62-31-7681
Synonyms:
(3H)-Dopamine
.Beta.-(3,4-Dihydroxyphenyl)ethylamine hydrochloride
.alpha.-(3,4-Dihydroxyphenyl)-.beta.-aminoethane
1,2-Benzenediol, 4-(2-aminoethyl)- (9CI)
1,2-Benzenediol, 4-(2-aminoethyl)-, hydrochloride
1,2-Benzenediol, 4-(2-aminoethyl)-, labeled with tritium
153C5321-5FEE-4B0B-8925-F388F0EEEBD1
2-(3,4-Dihydroxyphenyl)ethylamine
2-(3,4-dihydroxyphenyl)ethylamine
2-benzenediol
3,4-Dihydroxyphenethylamine
3,4-Dihydroxyphenethylamine hydrochloride
3,4-Dihydroxyphenylethylamine
3,4-dihydroxyphenethylamine
3-Hydroxtyramine
3-Hydroxytyramine
3-Hydroxytyramine Hydrobromide
3-Hydroxytyramine hydrochloride
4-(2-Aminoethyl)-1,
4-(2-Aminoethyl)-1,2-benzenediol
4-(2-Aminoethyl)-1,2-bezenediol
4-(2-Aminoethyl)-Pyrocatechol
4-(2-Aminoethyl)benzene-1,2-diol
4-(2-Aminoethyl)catechol
4-(2-Aminoethyl)pyrocatechol
4-(2-Aminoethyl)pyrocatechol hydrochloride
4-(2-aminoethyl)-pyrocatechol
50444-17-2
51-61-6
62-31-7 (HYDROCHLORIDE)
AC1L19S5
AC1Q54AX
AC1Q54AY
AKOS003790978
ASL 279
BIDD:ER0506
BPBio1_001123
BSPBio_001932
Biomol-NT_000001
C03758
CHEBI:18243
CHEMBL59
CID681
D07870
DB00988
Deoxyepinephrine
DivK1c_000780
Dopamin
Dopamina
Dopamina [INN-Spanish]
Dopamine
Dopamine (INN)
Dopamine (USAN)(*hydrochloride*)
Dopamine [INN:BAN]
Dopaminum
Dopaminum [INN-Latin]
Dopastat
Dophamine
Dynatra
EINECS 200-110-0
HSDB 3068
Hydroxytyramin
Hydroxytyramine
IDI1_000780
IP 498
Intropin
Intropin [*hydrochloride*]
KBio1_000780
 
KBio2_001492
KBio2_002388
KBio2_002484
KBio2_004060
KBio2_004956
KBio2_005052
KBio2_006628
KBio2_007524
KBio2_007620
KBio3_001152
KBio3_002867
KBio3_002962
KBioGR_001129
KBioGR_002388
KBioGR_002484
KBioSS_001492
KBioSS_002393
KBioSS_002491
KW-3-060
L-DOPAMINE
L000232
LDP
LS-159
Lopac-H-8502
Lopac0_000586
Medopa (TN)
MolPort-001-641-000
NCGC00015519-01
NCGC00015519-08
NCGC00096050-01
NCGC00096050-02
NCGC00096050-03
NCGC00096050-04
NCGC00096050-05
NINDS_000780
NSC 173182
NSC169105
NSC173182
Oprea1_088821
Oxytyramine
Pyrocatechol, 4-(2-aminoethyl)- (8CI)
Pyrocatechol, 4-(2-aminoethyl)-, hydrochloride
Revimine
Revivan
SPBio_001205
SPECTRUM1505155
ST048774
STK301601
Spectrum2_001023
Spectrum3_000406
Spectrum4_000525
Spectrum5_000945
Spectrum_001012
UNII-VTD58H1Z2X
UPCMLD0ENAT5885989:001
a-(3,4-Dihydroxyphenyl)-b-aminoethane
alpha-(3,4-Dihydroxyphenyl)-beta-aminoethane
cMAP_000036
cMAP_000065
dopamine
hydroxytyramine
intropin
m-Hydroxytyramine hydrochloride
nchembio.105-comp9
nchembio.107-comp4
nchembio.284-comp1
nchembio.78-comp16
nchembio.89-comp3
nchembio705-8
nchembio801-comp8
14
Risperidoneapproved, investigationalPhase 4492106266-06-25073
Synonyms:
106266-06-2
3-(2-(4-(6-Fluoro-1,2-benzisoxazol-3-yl)piperidino)ethyl)-6,7,8,9-tetrahydro-2-methyl-4H-pyrido(1,2-a)pyrimidin-4-one
3-(2-[4-(6-fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl)-2-methyl-6,7,8,9-tetrahydro-pyrido[
3-(2-[4-(6-fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl)-2-methyl-6,7,8,9-tetrahydropyrido[1,
3-[2-[-4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
3-[2-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]-6,7,8,9-tetrahydro-2-methyl-4H-pyrido [1,2-a] pyrimidin-4-one
3-[2-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)piperi-dino]ethyl]-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]-pyrimidin-4-one
3-[2-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
3-[2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl]-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one
3-[2-[4-(6-fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl]-2-methyl-6,7,8,9-tetrahydropyrido[1,
3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one
3-{2-[4-(6-fluoro-1,2-benzisoxazol-3-yl)piperidin-1-yl]ethyl}-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one
3-{2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl}-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one
AB00514010
AC-1306
AC1L1JJU
BIDD:GT0262
BRD-K53857191-001-04-5
BRN 4891881
Belivon
Bio-0092
Buspirone
C23H27FN4O2
CAS-106266-06-2
CHEBI:8871
CHEMBL85
CID5073
CPD000466323
Consta, Risperdal
D00426
D018967
DB00734
EU-0101074
HMS1571M19
HMS2051H07
HMS2089C22
HSDB 7580
I01-1156
Jsp000573
KS-1106
L000510
LS-134196
Lopac-R-118
MLS000759429
MLS001165758
MLS001424081
MolPort-002-885-858
 
NCGC00015883-01
NCGC00015883-02
NCGC00015883-03
NCGC00094352-01
NCGC00094352-02
NCGC00094352-03
NCGC00179257-01
Prestwick0_001029
Prestwick1_001029
R 62 766
R 64 766, Risperdal, Risperidone
R 64,766
R 64766
R-118
R-64,766
R-64-766
R-64766
R64,766
R64766
Rispen
Risperdal
Risperdal (TN)
Risperdal Consta
Risperdal M-Tab
Risperidal
Risperidal M-Tab
Risperidona
Risperidona [Spanish]
Risperidone
Risperidone (JAN/USAN/INN)
Risperidone (RIS)
Risperidone [USAN:BAN:INN]
Risperidone, placebo
Risperidonum
Risperidonum [Latin]
Risperin
Rispolept
Rispolin
S1615_Selleck
SAM001246595
SMR000466323
SPBio_003078
STK646402
Sequinan
Spiron
TL8000230
UNII-L6UH7ZF8HC
risperdone
risperidone
15Antibiotics, AntitubercularPhase 4, Phase 2, Phase 17180
16Peripheral Nervous System AgentsPhase 4, Phase 2, Phase 3, Phase 123689
17AnestheticsPhase 4, Phase 2, Phase 3, Phase 19596
18CoagulantsPhase 4, Phase 3, Phase 2, Phase 11500
19Anti-Arrhythmia AgentsPhase 43093
20Anti-Infective AgentsPhase 4, Phase 2, Phase 122062
21HemostaticsPhase 4, Phase 3, Phase 2, Phase 11443
22Antifibrinolytic AgentsPhase 4, Phase 3, Phase 2, Phase 1484
23Anti-Bacterial AgentsPhase 4, Phase 2, Phase 111226
24Neurotransmitter AgentsPhase 4, Phase 2, Phase 118340
25AnalgesicsPhase 4, Phase 1, Phase 211733
26Vasodilator AgentsPhase 43543
27Platelet Aggregation InhibitorsPhase 42516
28AnticonvulsantsPhase 4, Phase 22695
29Antitubercular AgentsPhase 4, Phase 21343
30Antimanic AgentsPhase 4, Phase 2814
31Adrenergic AgentsPhase 45352
32Psychotropic DrugsPhase 4, Phase 26430
33Sodium Channel BlockersPhase 41593
34Diuretics, Potassium SparingPhase 41917
35Cytochrome P-450 CYP3A InducersPhase 41119
36Tranquilizing AgentsPhase 4, Phase 24265
37Anesthetics, GeneralPhase 42934
38Analgesics, OpioidPhase 43238
39Antitussive AgentsPhase 4542
40Central Nervous System DepressantsPhase 4, Phase 2, Phase 313403
41Hypnotics and SedativesPhase 42616
42Autonomic AgentsPhase 4, Phase 1, Phase 210150
43Antihypertensive AgentsPhase 44207
44Adrenergic AntagonistsPhase 41573
45Adrenergic beta-1 Receptor AntagonistsPhase 4364
46Adrenergic beta-AntagonistsPhase 41193
47NarcoticsPhase 43646
48Chlorpheniramine, phenylpropanolamine drug combinationPhase 4641
49Anesthetics, IntravenousPhase 42538
50calcium channel blockersPhase 41985

Interventional clinical trials:

(show top 50)    (show all 238)
idNameStatusNCT IDPhase
1Celiprolol in Patients With Ehlers-Danlos Syndrome, Vascular TypeCompletedNCT00190411Phase 4
2Double Blind Randomized Study Into the Efficacy of Codeine Phosphate Analgesia After Cleft Palate Repair in InfantsCompletedNCT00386269Phase 4
3Acid Tranexamic Effectiveness in Reducing the Intraoperative Bleeding in PalatoplastyCompletedNCT02422056Phase 4
4The Effect of Deliberate Hypotension on QTc, Tp-e Intervals and Heart Rate VariabilityCompletedNCT01634594Phase 4
5Efficacy, Safety, and Tolerability of Oxcarbazepine Monotherapy in Children With Partial SeizuresCompletedNCT00275912Phase 4
6The Efficacy and Population Pharmacokinetics of Tranexamic Acid for Craniosynostosis SurgeryRecruitingNCT02188576Phase 4
7The Use of Fibrin Sealant to Reduce Post Operative Pain in Cleft Palate SurgeryRecruitingNCT02953145Phase 4
8The Role of Antibiotic Prophylaxis in Cleft Palate and Velopharyngeal Insufficiency RepairRecruitingNCT02688634Phase 4
9The Psychiatric and Cognitive Phenotypes in Velocardiofacial SyndromeRecruitingNCT00768820Phase 4
10Dexmedetomidine vs Placebo for Pediatric Cleft Palate RepairNot yet recruitingNCT02915042Phase 4
11Tranexamic Acid for Craniofacial SurgeryTerminatedNCT00722436Phase 4
12Comparison of a Bone Product to Bone Dust in Ossification of Small Calvarial Defects.WithdrawnNCT01006148Phase 4
13Comparative Results of Maxillary Deficiency Treatment by Fixed Tongue Appliance and Fixed Facemask in Growing PatientsUnknown statusNCT00916084Phase 3
14Indicated Prevention With Long-chain Polyunsaturated Omega-3 Fatty Acids in Patients With 22q11 Microdeletion Syndrome.Unknown statusNCT02070211Phase 2, Phase 3
15Posterior Compression Distraction Reduction (CDR)Technique in the Treatment of BI-AADUnknown statusNCT02463630Phase 3
16Blood Loss and Transfusion Requirement in Infants Treated With Tranexamic AcidUnknown statusNCT01094977Phase 3
17Comparative Study Between Levobupivacaine and Bupivacaine for Nerve Block During Pediatric Primary Cleft Palate SurgeryCompletedNCT02923869Phase 2, Phase 3
18Genetic Testing of Noonan Subjects Previously Treated With Norditropin®. An Extension to Trial GHNOO-1658CompletedNCT01529944Phase 3
19Oral Cleft Prevention Trial in BrazilCompletedNCT00098319Phase 3
20Comparative Results of Maxillary Deficiency Treatment by Tongue Plate and Facemask in Growing PatientsCompletedNCT00519415Phase 3
21Somatropin Effect on Linear Growth and Final Height in Subjects With Noonan SyndromeCompletedNCT01529840Phase 3
22Effect of MAXOMAT ® on the Growth of Small Children to NOONAN's SyndromeCompletedNCT00452725Phase 3
23Oral Cleft Prevention ProgramCompletedNCT00397917Phase 3
24Clinical Trial of New Elastomer for Maxillofacial ProstheticsCompletedNCT00123097Phase 3
25Assessing the Results of Lip Surgery in Patients With Cleft Lip and PalateCompletedNCT00070811Phase 2, Phase 3
26Treatment With HMG-COA Reductase Inhibitor of Growth and Bone Abnormalities in Children With Noonan SyndromeRecruitingNCT02713945Phase 3
27Preventive EXACYL® on Perioperative Bleeding During Orthognathism of Maxillary SurgeryRecruitingNCT02702128Phase 3
28Effects of PTH Replacement on Bone in HypoparathyroidismActive, not recruitingNCT00395538Phase 3
29Investigating the Long-term Efficacy and Safety of Two Doses of NN-220 (Somatropin) in Short Stature Due to Noonan SyndromeActive, not recruitingNCT01927861Phase 3
30Phase II Study of Dietary Cholesterol for Smith-Lemli-Opitz SyndromeUnknown statusNCT00004347Phase 2
31Cleft Palate Surgery and Speech DevelopmentCompletedNCT00004639Phase 2
32Rubinstein-Taybi Syndrome: Functional Imaging and Therapeutic TrialCompletedNCT01619644Phase 2
33A Trial to Evaluate the Safety, Local Tolerability, Pharmacokinetics and Pharmacodynamics of LDE225 on Skin Basal Cell Carcinomas in Gorlin Syndrome PatientsCompletedNCT00961896Phase 2
34Cell Therapy for Craniofacial Bone DefectsCompletedNCT01616953Phase 1, Phase 2
35Clinical Trial of Fat Grafts Supplemented With Adipose-derived Regenerative CellsCompletedNCT01674439Phase 2
36Treatment of the Cholesterol Defect in Smith-Lemli-Opitz SyndromeCompletedNCT00272844Phase 1, Phase 2
37Simvastatin Therapy in Smith-Lemli-Opitz SyndromeCompletedNCT00064792Phase 2
38Prenatal Screening For Smith-Lemli-Opitz SyndromeCompletedNCT00070850Phase 2
39Short-term Behavioral Effects of Cholesterol Therapy in Smith-Lemli-Opitz SyndromeCompletedNCT00114634Phase 2
40Does Use of Rigid Fixation After Removing Distraction Osteogenesis Device Reduce the Relapse?CompletedNCT02350803Phase 2
41Preoperative Antibiotics StudyCompletedNCT00760006Phase 2
42Alendronate to Treat Polyostotic Fibrous Dysplasia and McCune-Albright SyndromeCompletedNCT00001728Phase 2
43Pilot Study of Thalidomide to Treat Sjogren's SyndromeCompletedNCT00001599Phase 2
44Safety of and Immune Response to the Human Papillomavirus (HPV) Vaccine in HIV-Infected WomenCompletedNCT00604175Phase 2
45Phase 2 Study to Evaluate Safety, Pharmacokinetics, Immunogenicity and Pharmacodynamics/Efficacy of EDI200 in Male Infants With X-Linked Hypohidrotic Ectodermal Dysplasia (XLHED)CompletedNCT01775462Phase 2
463D-Printed CPAP Masks for Children With Obstructive Sleep ApneaRecruitingNCT02261857Phase 1, Phase 2
47Improvement of the Appearance of Cleft Lip Scars Using BotoxRecruitingNCT02247193Phase 1, Phase 2
48Efficacy of Amicar for Children Having Craniofacial SurgeryRecruitingNCT02229968Phase 2
49Effects of Oral Melatonin on Neurosensory Recovery Following Facial OsteotomiesRecruitingNCT02889432Phase 2
50Ambrisentan in Single VentricleRecruitingNCT02080637Phase 2

Search NIH Clinical Center for Macrocephaly with Multiple Epiphyseal Dysplasia and Distinctive Facies


Cochrane evidence based reviews: craniofacial abnormalities

Genetic Tests for Macrocephaly with Multiple Epiphyseal Dysplasia and Distinctive...

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Anatomical Context for Macrocephaly with Multiple Epiphyseal Dysplasia and Distinctive...

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MalaCards organs/tissues related to Macrocephaly with Multiple Epiphyseal Dysplasia and Distinctive Facies:

36
Brain, Bone

Publications for Macrocephaly with Multiple Epiphyseal Dysplasia and Distinctive...

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Variations for Macrocephaly with Multiple Epiphyseal Dysplasia and Distinctive...

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UniProtKB/Swiss-Prot genetic disease variations for Macrocephaly with Multiple Epiphyseal Dysplasia and Distinctive Facies:

70
id Symbol AA change Variation ID SNP ID
1KIF7p.Asn1060SerVAR_071185

Clinvar genetic disease variations for Macrocephaly with Multiple Epiphyseal Dysplasia and Distinctive Facies:

5
id Gene Variation Type Significance SNP ID Assembly Location
1KIF7NM_ 198525.2(KIF7): c.3179A> G (p.Asn1060Ser)SNVPathogenicrs886039282GRCh38Chr 15, 89630426: 89630426

Expression for genes affiliated with Macrocephaly with Multiple Epiphyseal Dysplasia and Distinctive...

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Search GEO for disease gene expression data for Macrocephaly with Multiple Epiphyseal Dysplasia and Distinctive Facies.

Pathways for genes affiliated with Macrocephaly with Multiple Epiphyseal Dysplasia and Distinctive...

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GO Terms for genes affiliated with Macrocephaly with Multiple Epiphyseal Dysplasia and Distinctive...

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Sources for Macrocephaly with Multiple Epiphyseal Dysplasia and Distinctive...

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet