MCID: MGC006
MIFTS: 11

Magic Syndrome malady

Bone category

Summaries for Magic Syndrome

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33MalaCards
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MalaCards: Magic Syndrome, also known as mouth and genital ulcers with inflamed cartilage, is related to aortic aneurysm and relapsing polychondritis. An important gene associated with Magic Syndrome is TNF (tumor necrosis factor).

Aliases & Classifications for Magic Syndrome

Sources:
49Orphanet
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Bone


Aliases & Descriptions:

magic syndrome 49
mouth and genital ulcers with inflamed cartilage 49


Related Diseases for Magic Syndrome

Sources:
17GeneCards, 18GeneDecks
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Diseases related to Magic Syndrome via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1aortic aneurysm10.2
2relapsing polychondritis10.0
3aortitis10.0
4arc syndrome10.0
5aortic valve insufficiency10.0

Graphical network of diseases related to Magic Syndrome:



Diseases related to magic syndrome

Clinical Features for Magic Syndrome

Drugs & Therapeutics for Magic Syndrome

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Magic Syndrome

Drug clinical trials:

Search ClinicalTrials for Magic Syndrome

Search NIH Clinical Center for Magic Syndrome

Search CenterWatch for Magic Syndrome

Genetic Tests for Magic Syndrome

Anatomical Context for Magic Syndrome

Animal Models for Magic Syndrome or affiliated genes

Sources:
28inGenious Targeting Laboratory
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Publications for Magic Syndrome

Sources:
51PubMed
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Articles related to Magic Syndrome:

(show all 13)
idTitleAuthorsYear
1
The search for a magic bullet to fight multiple organ failure secondary to ischemia/reperfusion injury and abdominal compartment syndrome. (22765997)
2013
2
A case of severe MAGIC syndrome treated successfully with the tumor necrosis factor-alpha inhibitor infliximab. (20414125)
2010
3
Aortic aneurysm in MAGIC syndrome successfully managed with combined anti-TNF-alpha and stent grafting. (19549787)
2009
4
Magic syndrome and true aortic aneurysm. (17657547)
2008
5
Mouth and genital ulcers with inflamed cartilage (MAGIC) syndrome complicated by aneurysmal aortitis. (17762460)
2007
6
Two Japanese cases with MAGIC syndrome (mouth and genital ulcers with inflamed cartilage). (17067440)
2006
7
Transverse aortic arch replacement associated with MAGIC syndrome: case report and literature review. (16779521)
2006
8
Severe recurrent neurological disease in the MAGIC syndrome. (15124284)
2004
9
The magic of immersion oil: gray platelet syndrome. (9658735)
1998
10
Mouth and genital ulcers with inflamed cartilage (MAGIC syndrome): a case report and literature review. (9365335)
1997
11
Aortic insufficiency and recurrent valve prosthesis dehiscence in MAGIC syndrome. (8474085)
1993
12
The MAGIC syndrome (mouth and genital ulcers with inflamed cartilage). (2360844)
1990
13
Mouth and genital ulcers with inflamed cartilage: MAGIC syndrome. Five patients with features of relapsing polychondritis and BehAset's disease. (4014306)
1985

Genetic Variations for Magic Syndrome

Expression for genes affiliated with Magic Syndrome

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Magic Syndrome

Search GEO for disease gene expression data for Magic Syndrome.

Pathways for genes affiliated with Magic Syndrome

Compounds for genes affiliated with Magic Syndrome

GO Terms for genes affiliated with Magic Syndrome

Products for genes affiliated with Magic Syndrome

  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Magic Syndrome

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet