MCID: MGC006
MIFTS: 15

Magic Syndrome malady

Bone diseases, Rare diseases categories

Summaries for Magic Syndrome

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34MalaCards
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MalaCards: Magic Syndrome, also known as mouth and genital ulcers with inflamed cartilage, is related to aneurysm and aortic aneurysm. An important gene associated with Magic Syndrome is TNF (tumor necrosis factor). Affiliated tissues include bone.

Aliases & Classifications for Magic Syndrome

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50Orphanet
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases
Anatomical: Bone diseases


Aliases & Descriptions:

magic syndrome 50
mouth and genital ulcers with inflamed cartilage 50


Related Diseases for Magic Syndrome

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Sources:
18GeneCards, 19GeneDecks
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Diseases related to Magic Syndrome via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1aneurysm10.3
2aortic aneurysm10.2
3relapsing polychondritis10.0
4aortitis10.0
5neurologic diseases10.0

Graphical network of diseases related to Magic Syndrome:



Diseases related to magic syndrome

Symptoms for Magic Syndrome

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Drugs & Therapeutics for Magic Syndrome

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Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials
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Approved drugs:

Search CenterWatch for Magic Syndrome

Drug clinical trials:

Search ClinicalTrials for Magic Syndrome

Search NIH Clinical Center for Magic Syndrome

Search CenterWatch for Magic Syndrome

Genetic Tests for Magic Syndrome

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Anatomical Context for Magic Syndrome

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34MalaCards
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MalaCards organs/tissues related to Magic Syndrome:

34
Bone

Animal Models for Magic Syndrome or affiliated genes

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Publications for Magic Syndrome

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Sources:
53PubMed
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Articles related to Magic Syndrome:

(show all 11)
idTitleAuthorsYear
1
A case of severe MAGIC syndrome treated successfully with the tumor necrosis factor-alpha inhibitor infliximab. (20414125)
2010
2
Aortic aneurysm in MAGIC syndrome successfully managed with combined anti-TNF-alpha and stent grafting. (19549787)
2009
3
Magic syndrome and true aortic aneurysm. (17657547)
2008
4
Mouth and genital ulcers with inflamed cartilage (MAGIC) syndrome complicated by aneurysmal aortitis. (17762460)
2007
5
Two Japanese cases with MAGIC syndrome (mouth and genital ulcers with inflamed cartilage). (17067440)
2006
6
Transverse aortic arch replacement associated with MAGIC syndrome: case report and literature review. (16779521)
2006
7
Severe recurrent neurological disease in the MAGIC syndrome. (15124284)
2004
8
Mouth and genital ulcers with inflamed cartilage (MAGIC syndrome): a case report and literature review. (9365335)
1997
9
Aortic insufficiency and recurrent valve prosthesis dehiscence in MAGIC syndrome. (8474085)
1993
10
The MAGIC syndrome (mouth and genital ulcers with inflamed cartilage). (2360844)
1990
11
Mouth and genital ulcers with inflamed cartilage: MAGIC syndrome. Five patients with features of relapsing polychondritis and BehAset's disease. (4014306)
1985

Variations for Magic Syndrome

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Expression for genes affiliated with Magic Syndrome

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Sources:
2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Magic Syndrome

Search GEO for disease gene expression data for Magic Syndrome.

Pathways for genes affiliated with Magic Syndrome

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Compounds for genes affiliated with Magic Syndrome

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GO Terms for genes affiliated with Magic Syndrome

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Products for genes affiliated with Magic Syndrome

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Magic Syndrome

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet