MCID: MLG018
MIFTS: 23

Malignant Giant Cell Tumor of Soft Parts

Categories: Cancer diseases

Aliases & Classifications for Malignant Giant Cell Tumor of Soft Parts

MalaCards integrated aliases for Malignant Giant Cell Tumor of Soft Parts:

Name: Malignant Giant Cell Tumor of Soft Parts 12 14
Malignant Giant Cell Neoplasm of Soft Parts 12

Classifications:



External Ids:

Disease Ontology 12 DOID:5638
NCIt 46 C8380
SNOMED-CT 64 48460009
UMLS 69 C0334554

Summaries for Malignant Giant Cell Tumor of Soft Parts

MalaCards based summary : Malignant Giant Cell Tumor of Soft Parts, also known as malignant giant cell neoplasm of soft parts, is related to malignant giant cell tumor and dermatofibrosarcoma protuberans. An important gene associated with Malignant Giant Cell Tumor of Soft Parts is S100B (S100 Calcium Binding Protein B), and among its related pathways/superpathways are Lysosome and Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers. Affiliated tissues include prostate and skin.

Related Diseases for Malignant Giant Cell Tumor of Soft Parts

Diseases related to Malignant Giant Cell Tumor of Soft Parts via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 59)
# Related Disease Score Top Affiliating Genes
1 malignant giant cell tumor 30.5 ACP5 ACTC1 S100B
2 dermatofibrosarcoma protuberans 30.0 ACTC1 S100B
3 giant cell tumor 10.4
4 myopericytoma 10.3 ACTC1 S100B
5 ossifying fibromyxoid tumor 10.3 ACTC1 S100B
6 syringocystadenoma papilliferum 10.3 ACTC1 S100B
7 angiocentric glioma 10.3 ACTC1 S100B
8 pleomorphic liposarcoma 10.2 ACTC1 S100B
9 cutaneous fibrous histiocytoma 10.2 ACTC1 S100B
10 spindle cell sarcoma 10.2 ACTC1 S100B
11 spiradenoma 10.2 ACTC1 S100B
12 papillary ependymoma 10.2 CD68 S100B
13 hemangiopericytoma, malignant 10.2 ACTC1 S100B
14 light chain deposition disease 10.2 ACTC1 CD68
15 polymorphous low-grade adenocarcinoma 10.2 ACTC1 S100B
16 granular cell tumor 10.2 CD68 S100B
17 meningeal melanocytoma 10.2 CD68 S100B
18 ischemic fasciitis 10.2 ACTC1 CD68
19 myoepithelioma 10.1 ACTC1 S100B
20 juvenile xanthogranuloma 10.1 LYZ S100B
21 histiocytic sarcoma 10.1 CD68 S100B
22 pleomorphic adenoma 10.1 ACTC1 S100B
23 central nervous system sarcoma 10.1 CD68 LYZ
24 melanotic neurilemmoma 10.1 CD68 LYZ
25 adult xanthogranuloma 10.1 CD68 LYZ
26 liver sarcoma 10.1 CD68 LYZ
27 inflammatory myofibroblastic tumor 10.1 ACTC1 S100B
28 granulomatous myositis 10.1 CD68 LYZ
29 leiomyosarcoma 10.0 ACTC1 S100B
30 xanthogranulomatous pyelonephritis 10.0 CD68 LYZ
31 aleukemic leukemia cutis 10.0 CD68 LYZ
32 congenital epulis 10.0 CD68 LYZ
33 ulcerative stomatitis 10.0 CD68 LYZ
34 xanthogranulomatous cholecystitis 10.0 CD68 LYZ
35 gliosarcoma 9.9 ACTC1 S100B
36 reticulum cell sarcoma 9.9 ACTC1 PTPRC
37 prostatitis 9.9
38 nodular tenosynovitis 9.9 CD68 PTPRC
39 olfactory neuroblastoma 9.9 PTPRC S100B
40 extracutaneous mastocytoma 9.9 CD68 PTPRC
41 glomeruloid hemangioma 9.9 CD68 PTPRC
42 brain sarcoma 9.9 CD68 PTPRC
43 sarcomatoid squamous cell skin carcinoma 9.9 CD68 PTPRC
44 hodgkin's lymphoma, lymphocytic depletion 9.9 CD68 PTPRC
45 conventional fibrosarcoma 9.9 CD68 PTPRC
46 photokeratitis 9.9 CD68 PTPRC
47 malignant peripheral nerve sheath tumor 9.9 ACTC1 S100B
48 pigmented villonodular synovitis 9.9 ACP5 PTPRC
49 langerhans cell histiocytosis 9.8 PTPRC S100B
50 histiocytosis 9.8 PTPRC S100B

Graphical network of the top 20 diseases related to Malignant Giant Cell Tumor of Soft Parts:



Diseases related to Malignant Giant Cell Tumor of Soft Parts

Symptoms & Phenotypes for Malignant Giant Cell Tumor of Soft Parts

Drugs & Therapeutics for Malignant Giant Cell Tumor of Soft Parts

Search Clinical Trials , NIH Clinical Center for Malignant Giant Cell Tumor of Soft Parts

Genetic Tests for Malignant Giant Cell Tumor of Soft Parts

Anatomical Context for Malignant Giant Cell Tumor of Soft Parts

MalaCards organs/tissues related to Malignant Giant Cell Tumor of Soft Parts:

38
Prostate, Skin

Publications for Malignant Giant Cell Tumor of Soft Parts

Articles related to Malignant Giant Cell Tumor of Soft Parts:

# Title Authors Year
1
Malignant giant cell tumor of soft parts. ( 14997349 )
2004
2
Malignant giant cell tumor of soft parts in a mare. ( 14524631 )
2003
3
Soft tissue giant cell tumor of low malignant potential: a proposal for the reclassification of malignant giant cell tumor of soft parts. ( 10496598 )
1999
4
Metastatic dermatofibrosarcoma protuberans with fibrosarcomatous change in the absence of local recurrence. A case report of simultaneous occurrence with a malignant giant cell tumor of soft parts. ( 8319177 )
1993
5
Malignant giant cell tumor of soft parts presenting as a skin tumor. ( 2658646 )
1989
6
Sarcomatoid carcinoma (so-called pseudosarcoma) of the larynx simulating malignant giant cell tumor of soft parts. A case report. ( 6465100 )
1984
7
The importance of recognizing malignant giant cell tumor of soft parts. ( 277073 )
1978
8
Malignant giant cell tumor of soft parts. An ultrastructural study of four cases. ( 195704 )
1977
9
Primary prostatic malignant giant cell tumor of soft parts. ( 1067447 )
1976
10
Malignant giant cell tumor of soft parts. An analysis of 32 cases. ( 5031245 )
1972

Variations for Malignant Giant Cell Tumor of Soft Parts

Expression for Malignant Giant Cell Tumor of Soft Parts

Search GEO for disease gene expression data for Malignant Giant Cell Tumor of Soft Parts.

Pathways for Malignant Giant Cell Tumor of Soft Parts

Pathways related to Malignant Giant Cell Tumor of Soft Parts according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.05 ACP5 CD68
2 10.69 CD68 PTPRC

GO Terms for Malignant Giant Cell Tumor of Soft Parts

Biological processes related to Malignant Giant Cell Tumor of Soft Parts according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 defense response to Gram-positive bacterium GO:0050830 8.96 ACP5 LYZ
2 neutrophil degranulation GO:0043312 8.8 CD68 LYZ PTPRC

Sources for Malignant Giant Cell Tumor of Soft Parts

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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