MCID: MLG097
MIFTS: 18

Malignant Mesenchymal Tumor malady

Cancer diseases category

Summaries for Malignant Mesenchymal Tumor

About this section
Sources:
32MalaCards
See all sources

Fully expand this MalaCard

Export this MalaCard
MalaCards: Malignant Mesenchymal Tumor, also known as malignant mesenchymoma, is related to rhabdomyosarcoma and sarcoma. An important gene associated with Malignant Mesenchymal Tumor is IGFBP3 (insulin-like growth factor binding protein 3), and among its related pathways are Integrated Pancreatic Cancer Pathway and Celecoxib Pathway, Pharmacodynamics. The compounds exemestane and silymarin have been mentioned in the context of this disorder.

Aliases & Classifications for Malignant Mesenchymal Tumor

About this section
Sources:
42NIH Rare Diseases, 60UMLS
See all sources

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases


Aliases & Descriptions:

malignant mesenchymal tumor 42 60
malignant mesenchymoma 42


Related Diseases for Malignant Mesenchymal Tumor

About this section
Sources:
17GeneCards, 18GeneDecks
See all sources

Graphical network of the top 20 diseases related to Malignant Mesenchymal Tumor:



Diseases related to malignant mesenchymal tumor

Clinical Features for Malignant Mesenchymal Tumor

About this section

Drugs & Therapeutics for Malignant Mesenchymal Tumor

About this section
Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
See all sources

Approved drugs:

Search CenterWatch for Malignant Mesenchymal Tumor

Drug clinical trials:

Search ClinicalTrials for Malignant Mesenchymal Tumor

Search NIH Clinical Center for Malignant Mesenchymal Tumor

Search CenterWatch for Malignant Mesenchymal Tumor

Genetic Tests for Malignant Mesenchymal Tumor

About this section

Anatomical Context for Malignant Mesenchymal Tumor

About this section

Animal Models for Malignant Mesenchymal Tumor or affiliated genes

About this section

Publications for Malignant Mesenchymal Tumor

About this section

Genetic Variations for Malignant Mesenchymal Tumor

About this section

Expression for genes affiliated with Malignant Mesenchymal Tumor

About this section
Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Malignant Mesenchymal Tumor

Search GEO for disease gene expression data for Malignant Mesenchymal Tumor.

Pathways for genes affiliated with Malignant Mesenchymal Tumor

About this section
Sources:
37NCBI BioSystems Database, 49PharmGKB
See all sources

Pathways related to Malignant Mesenchymal Tumor according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.1PTGS2, IGFBP3
29.1PTGS2, IGFBP3

Compounds for genes affiliated with Malignant Mesenchymal Tumor

About this section
Sources:
49PharmGKB, 44Novoseek, 59Tocris Bioscience, 11DrugBank, 28IUPHAR, 24HMDB
See all sources

Compounds related to Malignant Mesenchymal Tumor according to GeneCards/GeneDecks:

(show all 11)
idCompoundScoreTop Affiliating Genes
1exemestane49 44 59 1112.4IGFBP3, PTGS2
2silymarin449.4PTGS2, IGFBP3
3prostaglandin f2alpha449.3IGFBP3, PTGS2
4celecoxib44 59 28 49 11 2414.3PTGS2, IGFBP3
5egcg449.3IGFBP3, PTGS2
6curcumin449.2IGFBP3, PTGS2
7aspirin44 49 28 2412.2PTGS2, IGFBP3
8ly294002449.1IGFBP3, PTGS2
9cycloheximide449.1IGFBP3, PTGS2
10pge2449.0PTGS2, IGFBP3
11cisplatin44 49 59 1111.8PTGS2, IGFBP3

GO Terms for genes affiliated with Malignant Mesenchymal Tumor

About this section
Sources:
16Gene Ontology
See all sources

Biological processes related to Malignant Mesenchymal Tumor according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1negative regulation of cell proliferationGO:0082859.1PTGS2, IGFBP3
2positive regulation of apoptotic processGO:0430658.8PTGS2, IGFBP3

Products for genes affiliated with Malignant Mesenchymal Tumor

About this section
  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Malignant Mesenchymal Tumor

About this section
3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet