MCID: MLG074
MIFTS: 41

Malignant Mesenchymoma malady

Cancer diseases category
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Summaries for Malignant Mesenchymoma

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MalaCards based summary: Malignant Mesenchymoma, also known as malignant mesenchymal tumor, is related to leiomyosarcoma and sarcoma. An important gene associated with Malignant Mesenchymoma is MYOG (myogenin (myogenic factor 4)), and among its related pathways are L1CAM interactions and Immune response Function of MEF2 in T lymphocytes. The compounds bromodeoxyuridine and 12-o-tetradecanoylphorbol 13-acetate have been mentioned in the context of this disorder. Affiliated tissues include bone, heart and kidney, and related mouse phenotype adipose tissue.

Aliases & Classifications for Malignant Mesenchymoma

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Malignant Mesenchymoma, Aliases & Descriptions:

Name: Malignant Mesenchymoma 8 10
Malignant Mesenchymal Tumor 62
 
Mesenchymoma, Malignant 8


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases


External Ids:

Disease Ontology8 DOID:5758
MeSH34 C535700
SNOMED-CT57 89623007
NCIt39 C4268

Related Diseases for Malignant Mesenchymoma

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Graphical network of the top 20 diseases related to Malignant Mesenchymoma:



Diseases related to malignant mesenchymoma

Symptoms for Malignant Mesenchymoma

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Drugs & Therapeutics for Malignant Mesenchymoma

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Drug clinical trials:

Search ClinicalTrials for Malignant Mesenchymoma

Search NIH Clinical Center for Malignant Mesenchymoma

Genetic Tests for Malignant Mesenchymoma

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Anatomical Context for Malignant Mesenchymoma

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MalaCards organs/tissues related to Malignant Mesenchymoma:

32
Bone, Heart, Kidney, Liver, Lung, Breast, Uterus, Prostate, Bone marrow, Brain, Small intestine, Thyroid, Cervix

Animal Models for Malignant Mesenchymoma or affiliated genes

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MGI Mouse Phenotypes related to Malignant Mesenchymoma:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053759.1MYOG, MYOD1

Publications for Malignant Mesenchymoma

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Articles related to Malignant Mesenchymoma:

(show top 50)    (show all 116)
idTitleAuthorsYear
1
Malignant mesenchymoma with widespread metastasis including bone marrow involvement in a dog. (25132008)
2014
2
Malignant mesenchymoma of the heart base in a dog with infiltration of the pericardium and metastasis to the lung. (22516086)
2012
3
Malignant mesenchymoma in the nasal cavity of a bull. (21306728)
2011
4
Malignant mesenchymoma of the thyroid: case report and literature review. (20572598)
2010
5
Malignant mesenchymoma surrounding the esophageal hiatus. (20103193)
2010
6
An intra-abdominal malignant mesenchymoma associated with nonabsorbable sutures in a ferret (Mustela putorius furo). (20224105)
2010
7
Uterine malignant mesenchymoma, arising in a leiomyoma, with pulmonary metastases. (17257144)
2007
8
Left atrial malignant mesenchymoma--emergency resection and mitral replacement. (17664193)
2007
9
Osteosarcoma with rhabdomyosarcomatous component or so-called malignant mesenchymoma of bone. (15792374)
2004
10
Primary osteochondrorhabdomyosarcoma (malignant mesenchymoma) of the fibula: a rare tumour in an unusual site -- case report and review of the literature. (15601312)
2004
11
Malignant mesenchymoma of the orbit: case report and review of the literature. (12578773)
2003
12
Malignant mesenchymoma of the pleura. (17670075)
2003
13
Malignant mesenchymoma of the uterus, arising in a leiomyoma. (11903599)
2002
14
Primary malignant mesenchymoma of the heart. (11788281)
2002
15
Giant malignant mesenchymoma of the spermatic cord with bidirectional differentiation. (11441285)
2001
16
Retroperitoneal malignant mesenchymoma: imaging findings in five cases. (9933683)
1999
17
Primary left atrial malignant mesenchymoma: a case report. (9607271)
1998
18
Malignant mesenchymoma of the spermatic cord with a brief review of the literature. (9179703)
1997
19
Maxillary malignant mesenchymoma and massive fibrous dysplasia. (9006514)
1997
20
Clinical image. Malignant mesenchymoma of the buttock. (8933808)
1996
21
Malignant mesenchymoma of the thigh. (7644947)
1995
22
Primary malignant mesenchymoma of bone: case report, literature review, and distinction of this entity from mesenchymal and dedifferentiated chondrosarcoma. (7644944)
1995
23
Malignant mesenchymoma of the spermatic cord. (8088727)
1994
24
Malignant mesenchymoma of the brain. A case report. (1603236)
1992
25
Case report: malignant mesenchymoma of the mediastinum. (1454238)
1992
26
Infantile malignant mesenchymoma: limb salvage therapy. (1813594)
1991
27
Malignant mesenchymoma: a very rare tumor of the peritoneum. Case report with a review of the literature. (2034003)
1991
28
Malignant mesenchymoma associated with a congenital lung cyst in a child: case report and review of the literature. (2235763)
1990
29
Primary malignant mesenchymoma of bone. (2189375)
1990
30
Malignant mesenchymoma of the larynx. (2370480)
1990
31
A case report of malignant mesenchymoma with discussion of musculoskeletal tumor staging: the Enneking system. (3174499)
1988
32
Hepatic malignant mesenchymoma in a dog. (3710891)
1986
33
Malignant mesenchymoma of the spermatic cord. (6583431)
1984
34
Malignant mesenchymoma of the small intestine. (6546496)
1984
35
Case report of a primary cystic sarcoma of the kidney, demonstrating fibrohistiocytic, osteoid, and cartilaginous components (malignant mesenchymoma). (7127261)
1982
36
Malignant mesenchymoma of the heart. (7136698)
1982
37
Malignant mesenchymoma obstructing the right ventricular outflow tract. (7457335)
1981
38
Malignant mesenchymoma developing 6 years after radical hysterectomy and postoperative radiotherapy for cervical carcinoma. (7308872)
1981
39
Roentgenographic findings in malignant mesenchymoma of bone. (7462884)
1980
40
Malignant mesenchymoma of the retroperitoneum: a case report. (45668)
1979
41
Case report. Paratesticular malignant mesenchymoma. (750460)
1978
42
Ganglioneuroblastoma associated with malignant mesenchymoma. (1182658)
1975
43
Malignant mesenchymoma. Case report with electron microscopic study. (1182662)
1975
44
Malignant mesenchymoma of mediastinum: a case report. (4781270)
1973
45
Malignant mesenchymoma of the mediastinum. Report of a case. (4731433)
1973
46
Congenital malignant mesenchymoma of the face. Case report. (5060326)
1972
47
Primary congenital malignant mesenchymoma of the eyelid. (5119569)
1971
48
MALIGNANT MESENCHYMOMA OF THE HEART. (14290326)
1965
49
Malignant mesenchymoma (haemangioblastomyxomatous variety) in a five-year-old boy. (13671401)
1959
50
Malignant mesenchymoma of the kidney: case report. (13417295)
1957

Variations for Malignant Mesenchymoma

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Expression for genes affiliated with Malignant Mesenchymoma

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Expression patterns in normal tissues for genes affiliated with Malignant Mesenchymoma

Search GEO for disease gene expression data for Malignant Mesenchymoma.

Pathways for genes affiliated with Malignant Mesenchymoma

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Pathways related to Malignant Mesenchymoma according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.1MYOG, MYOD1
2
Show member pathways
Development Role of HDAC and calcium calmodulin dependent kinase CaMK in control of skeletal myogenesis60
9.1MYOG, MYOD1
39.1MYOG, MYOD1
4
Show member pathways
9.1MYOG, MYOD1

Compounds for genes affiliated with Malignant Mesenchymoma

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Compounds related to Malignant Mesenchymoma according to GeneCards/GeneDecks:

(show all 16)
idCompoundScoreTop Affiliating Genes
1bromodeoxyuridine449.4MYOG, MYOD1
212-o-tetradecanoylphorbol 13-acetate449.4MYOG, MYOD1
3butyrate449.4MYOG, MYOD1
4acetylcholine44 50 28 24 1113.4MYOG, MYOD1
5paraffin449.4MYOD1, MYOG
6fatty acid449.4MYOG, MYOD1
7creatinine449.4MYOG, MYOD1
8testosterone44 61 24 1112.3MYOG, MYOD1
9steroid449.3MYOD1, MYOG
10oligonucleotide449.3MYOG, MYOD1
11vegf449.2MYOG, MYOD1
12oxygen44 2410.2MYOG, MYOD1
13estrogen449.1MYOD1, MYOG
14glucose449.1MYOG, MYOD1
15retinoic acid44 2410.0MYOG, MYOD1
16cysteine448.8MYOG, MYOD1

GO Terms for genes affiliated with Malignant Mesenchymoma

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Cellular components related to Malignant Mesenchymoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1transcription factor complexGO:0056679.1MYOG, MYOD1

Biological processes related to Malignant Mesenchymoma according to GeneCards/GeneDecks:

(show all 7)
idNameGO IDScoreTop Affiliating Genes
1muscle cell fate commitmentGO:0426939.3MYOG, MYOD1
2skeletal muscle fiber developmentGO:0487419.2MYOG, MYOD1
3cellular response to estradiol stimulusGO:0713929.2MYOG, MYOD1
4positive regulation of muscle cell differentiationGO:0511499.1MYOD1, MYOG
5positive regulation of transcription from RNA polymerase II promoterGO:0459449.1MYOG, MYOD1
6muscle cell differentiationGO:0426929.0MYOG, MYOD1
7skeletal muscle tissue developmentGO:0075198.8MYOG, MYOD1

Molecular functions related to Malignant Mesenchymoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1chromatin DNA bindingGO:0314909.1MYOG, MYOD1
2protein heterodimerization activityGO:0469829.1MYOG, MYOD1
3E-box bindingGO:0708889.0MYOG, MYOD1
4core promoter bindingGO:0010478.8MYOG, MYOD1

Products for genes affiliated with Malignant Mesenchymoma

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  • Antibodies
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Sources for Malignant Mesenchymoma

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet