MCID: MLG059
MIFTS: 28

Malignant Struma Ovarii malady

Category: Cancer diseases

Aliases & Classifications for Malignant Struma Ovarii

About this section

Aliases & Descriptions for Malignant Struma Ovarii:

Name: Malignant Struma Ovarii 10 12
 
Struma Ovarii, Malignant 10 65

Classifications:



External Ids:

Disease Ontology10 DOID:5208
SNOMED-CT59 18854008
NCIt42 C4291
UMLS65 C0334525

Summaries for Malignant Struma Ovarii

About this section
MalaCards based summary: Malignant Struma Ovarii, also known as struma ovarii, malignant, is related to multiple myeloma and hepatitis. An important gene associated with Malignant Struma Ovarii is TG (Thyroglobulin), and among its related pathways are and Central carbon metabolism in cancer. Affiliated tissues include thyroid, kidney and prostate, and related mouse phenotypes are nervous system and endocrine/exocrine gland.

Related Diseases for Malignant Struma Ovarii

About this section

Graphical network of the top 20 diseases related to Malignant Struma Ovarii:



Diseases related to malignant struma ovarii

Symptoms for Malignant Struma Ovarii

About this section

Drugs & Therapeutics for Malignant Struma Ovarii

About this section

Drugs for Malignant Struma Ovarii (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1HormonesPhase 111748

Interventional clinical trials:

idNameStatusNCT IDPhase
1Metabolic Effects of Synthetic Thyroid Hormone for Thyroid Cancer TreatmentCompletedNCT01441154Phase 1

Search NIH Clinical Center for Malignant Struma Ovarii

Genetic Tests for Malignant Struma Ovarii

About this section

Anatomical Context for Malignant Struma Ovarii

About this section

MalaCards organs/tissues related to Malignant Struma Ovarii:

33
Thyroid, Kidney, Prostate, Endothelial, Neutrophil, T cells, Myeloid

Animal Models for Malignant Struma Ovarii or affiliated genes

About this section

MGI Mouse Phenotypes related to Malignant Struma Ovarii:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00036317.7HRAS, KRT19, LGALS3, RET, TG
2MP:00053797.7AFP, HRAS, KRT19, RET, TG
3MP:00020067.5AFP, HRAS, KRT19, LGALS3, RET

Publications for Malignant Struma Ovarii

About this section

Articles related to Malignant Struma Ovarii:

(show top 50)    (show all 71)
idTitleAuthorsYear
1
Difference in clinical presentation, immunology profile and treatment response of type 1 autoimmune hepatitis between United Kingdom and Singapore patients. (27101826)
2016
2
Mechanosensitive CaA^a8_-permeable channels in human leukemic cells: pharmacological and molecular evidence for TRPV2. (25268680)
2015
3
Follicular variant of papillary thyroid carcinoma is a unique clinical entity: a population-based study of 10,740 cases. (23477346)
2013
4
Hsp90 inhibits I+-synuclein aggregation by interacting with soluble oligomers. (23948507)
2013
5
PLASMA LEVELS OF PENTRAXIN-3, AN INFLAMMATORY PROTEIN INVOLVED IN FERTILITY, ARE REDUCED IN WOMEN WITH POLYCYSTIC OVARY SYNDROME. (24347428)
2013
6
Resistin increases monolayer permeability of human coronary artery endothelial cells. (24386395)
2013
7
A novel COL7A1 gene mutation causing pretibial epidermolysis bullosa: report of a Chinese family with intra-familial phenotypical diversity. (23624125)
2013
8
A fatty gut feeling. (23567058)
2013
9
Features of the retinal environment which affect the activities and product profile of cholesterol-metabolizing cytochromes P450 CYP27A1 and CYP11A1. (22227097)
2012
10
Pheochromocytoma and pregnancy: a difficult and dangerous ordeal. (22977377)
2012
11
The death-promoting molecule tumour necrosis factor-related apoptosis inducing ligand (TRAIL) is not required for the development of peripheral lymphopenia or granuloma necrosis during infection with virulent Mycobacterium avium. (21470210)
2011
12
Routine upfront abciximab versus standard periprocedural therapy in patients undergoing primary percutaneous coronary intervention for cardiogenic shock: The PRAGUE-7 Study. An open randomized multicentre study. (21526919)
2011
13
Early-onset seizure variant of Rett syndrome: definition of the clinical diagnostic criteria. (19362436)
2010
14
Clinical evidence for overcoming capecitabine resistance in a woman with breast cancer terminating in radiologically occult micronodular pseudo-cirrhosis with portal hypertension: a case report. (20409335)
2010
15
Rapamycin promotes the osteoblastic differentiation of human embryonic stem cells by blocking the mTOR pathway and stimulating the BMP/Smad pathway. (19642865)
2010
16
Embracing emerging paradigms of G protein-coupled receptor agonism and signaling to address airway smooth muscle pathobiology in asthma. (18278482)
2008
17
Novel 5 alpha-steroid reductase (SRD5A3, type-3) is overexpressed in hormone-refractory prostate cancer. (17986282)
2008
18
Modulation of nucleobindin-1 and nucleobindin-2 by caspases. (18154733)
2008
19
Comparative efficacy and safety of extended-release and instant-release tolterodine in children with neural tube defects having cystometric abnormalities. (18631906)
2008
20
No association between polymorphisms of DAO and DAOA genes and homicidal behaviors in Korean schizophrenia. (17728673)
2007
21
Hepatopulmonary syndrome. (16207573)
2005
22
Immunogenetic association in patients with antineutrophil cytoplasmic antibodies (ANCA) from Mumbai, Maharashtra, India. (15848045)
2005
23
Simple way to improve accuracy in diagnosis of quadrant inflammatory disease: how to avoid adverse laparotomy by using plain CT. (15783013)
2005
24
Relationship between acute phase proteins and hoof horn haemorrhages in postpartum first-lactation heifers. (15083972)
2004
25
NHE-1 inhibition: from protection during acute ischaemia/reperfusion to prevention/reversal of myocardial remodelling. (14504689)
2003
26
Ureteral obstruction in a transplanted kidney secondary to a subserous myoma uteri. (12811258)
2003
27
Rod cyclic nucleotide-gated channels have a stoichiometry of three CNGA1 subunits and one CNGB1 subunit. (12467592)
2002
28
Association of genetic defects in primary resected lung adenocarcinoma revealed by targeted allelic imbalance analysis. (12356584)
2002
29
Intracellular redistribution of nucleolin upon interaction with the CD3epsilon chain of the T cell receptor complex. (11115514)
2001
30
Ultrasound evaluation of plantar fasciitis. (11028848)
2000
31
Initiation of genome replication: assembly and disassembly of replication-competent chromatin. (10713440)
2000
32
ALCOHOL: its metabolism and interaction with nutrients. (10940340)
2000
33
Conductive hearing loss in Beckwith-Wiedemann syndrome. (10375044)
1999
34
Distribution of phosphorylated GAP-43 (neuromodulin) in growth cones directly reflects growth cone behavior. (9622012)
1998
35
Targeted therapy of human malignant glioma in a mouse model by 2-5A antisense directed against telomerase RNA. (9681832)
1998
36
Expression of estrogen receptors during growth of human pancreatic adenocarcinoma cells (Capan-1)-relationship with differentiation. (9719420)
1998
37
Nocturnal frontal lobe epilepsy misdiagnosed as sleep apnea syndrome. (9696531)
1998
38
Fibrillin-1 in human cartilage: developmental expression and formation of special banded fibers. (9267468)
1997
39
Emerin, deficiency of which causes Emery-Dreifuss muscular dystrophy, is localized at the inner nuclear membrane. (10732816)
1997
40
Noninvolvement of CYP2E1 in the (omega-1)-hydroxylation of fatty acids in rat kidney microsomes. (9354595)
1997
41
Granulocyte-macrophage colony-stimulating factor receptor-targeted therapy of chemotherapy- and radiation-resistant human myeloid leukemias. (9168435)
1997
42
Transjugular intrahepatic portosystemic shunt as a treatment for protein-losing enteropathy caused by portal hypertension. (8942750)
1996
43
DNA ploidy, serum prostate specific antigen, histological grade and immunohistochemistry as predictive parameters of lymph node metastases in T1-T3/M0 prostatic adenocarcinoma. (7531589)
1995
44
Muir-Torre syndrome. (7712655)
1995
45
Modulation of proliferation and antigen expression of a cloned human glioblastoma by interleukin-4 alone and in combination with tumor necrosis factor-alpha and/or interferon-gamma. (8413882)
1993
46
Follicular colonization in thyroid lymphoma. (1632470)
1992
47
Apolipoprotein A1 Baltimore (Arg-10-->Leu), a new ApoA1 variant. (2108924)
1990
48
The role of metabolic acidosis in causing uremic hyperphosphatemia. (3007964)
1986
49
Proposed mechanism for colchicine poisoning of microtubules reassembled in vitro from Strongylocentrotus purpuratus sperm tail outer doublet tubulin. (7397118)
1980
50
EEG and the clinical course after cerebral hypoxia in childhood. (5100314)
1971

Variations for Malignant Struma Ovarii

About this section

Expression for genes affiliated with Malignant Struma Ovarii

About this section
Search GEO for disease gene expression data for Malignant Struma Ovarii.

Pathways for genes affiliated with Malignant Struma Ovarii

About this section

Pathways related to Malignant Struma Ovarii according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
1
Show member pathways
9.2
29.2HRAS, RET
39.2HRAS, RET
49.2HRAS, RET
59.2HRAS, RET

GO Terms for genes affiliated with Malignant Struma Ovarii

About this section

Sources for Malignant Struma Ovarii

About this section
2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet