MCID: MLG059
MIFTS: 29

Malignant Struma Ovarii malady

Category: Cancer diseases

Aliases & Classifications for Malignant Struma Ovarii

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Aliases & Descriptions for Malignant Struma Ovarii:

Name: Malignant Struma Ovarii 10 12
 
Struma Ovarii, Malignant 10 65

Classifications:



External Ids:

Disease Ontology10 DOID:5208
SNOMED-CT59 18854008
NCIt42 C4291
UMLS65 C0334525

Summaries for Malignant Struma Ovarii

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MalaCards based summary: Malignant Struma Ovarii, also known as struma ovarii, malignant, is related to struma ovarii and thyroiditis. An important gene associated with Malignant Struma Ovarii is TG (Thyroglobulin), and among its related pathways are VEGF Pathway (Tocris) and Central carbon metabolism in cancer. Affiliated tissues include thyroid, liver and endothelial, and related mouse phenotypes are nervous system and endocrine/exocrine gland.

Related Diseases for Malignant Struma Ovarii

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Diseases in the Struma Ovarii family:

malignant struma ovarii Benign Struma Ovarii

Diseases related to Malignant Struma Ovarii via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 51)
idRelated DiseaseScoreTop Affiliating Genes
1struma ovarii11.0
2thyroiditis10.6
3thyroid cancer, childhood10.3RET, TG
4perivascular epithelioid cell tumor10.3RET, TG
5graves' disease10.3
6thyroid cancer10.3
7hypothyroidism, congenital, due to thyroid dysgenesis or hypoplasia10.3LGALS3, TG
8papillary carcinoma10.2
9teratoma10.2
10hashimoto thyroiditis10.2RET, TG
11fallopian tube teratoma10.2AFP, TG
12fibrous synovial sarcoma10.1AFP, TG
13lung occult adenocarcinoma10.1RET, TG
14extrahepatic bile duct adenoma10.1AFP, KRT19
15stenosis of lacrimal sac10.1AFP, TG
16cervicitis10.1
17adenocarcinoma10.1
18cerebritis10.1
19meige syndrome10.1
20peritonitis10.1
21pseudo-meigs syndrome10.1
22parametritis10.1AFP, RET
23medullary thyroid carcinoma, familial10.0RET, TG
24acantholytic squamous cell skin carcinoma9.9AFP, KRT19
25sporadic pheochromocytoma/secreting paraganglioma9.9HRAS, RET
26intracystic papillary adenoma9.9HRAS, KRT19
27endemic goiter9.9LGALS3, RET, TG
28parenchymatous neurosyphilis9.9HRAS, TG
29cavernous hemangioma9.8HRAS, RET
30osteoclast-like giant cell neoplasm of the pancreas9.8HRAS, KRT19
31biliary tract intraductal papillary mucinous neoplasm9.8HRAS, KRT19
32tubular adenocarcinoma9.8AFP, KRT19
33mediastinum teratoma9.8AFP, RET, TG
34chondromalacia patellae9.7AFP, KRT19
35head and neck carcinoma9.7AFP, HRAS
36organ system benign neoplasm9.7HRAS, RET
37chronic inflammatory demyelinating polyradiculoneuropathy9.6HRAS, RET, TG
38hepatocellular adenoma9.4HRAS, KRT19
39mediastinal osteogenic sarcoma9.4KRT19, LGALS3, RET, TG
40serous cystadenocarcinoma9.4KRT19, LGALS3, RET, TG
41decubitus ulcer9.3HRAS, RET
42bile duct carcinoma9.3AFP, HRAS, KRT19
43brachyolmia9.3AFP, HRAS, KRT19
44tenosynovitis of foot and ankle9.3AFP, HRAS, KRT19
45familial abdominal aortic aneurysm9.1HRAS, LGALS3, RET, TG
46steroid inherited metabolic disorder9.1HRAS, LGALS3, RET, TG
47cell type cancer9.0AFP, HRAS, RET, TG
48frontotemporal dementia and/or amyotrophic lateral sclerosis 48.6HRAS, KRT19, LGALS3, RET, TG
49chorea, hereditary benign8.6HRAS, KRT19, LGALS3, RET, TG
50adrenal rest tumor8.6HRAS, KRT19, LGALS3, RET, TG

Graphical network of the top 20 diseases related to Malignant Struma Ovarii:



Diseases related to malignant struma ovarii

Symptoms for Malignant Struma Ovarii

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Drugs & Therapeutics for Malignant Struma Ovarii

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Drugs for Malignant Struma Ovarii (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1HormonesPhase 111748

Interventional clinical trials:

idNameStatusNCT IDPhase
1Metabolic Effects of Synthetic Thyroid Hormone for Thyroid Cancer TreatmentCompletedNCT01441154Phase 1

Search NIH Clinical Center for Malignant Struma Ovarii

Genetic Tests for Malignant Struma Ovarii

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Anatomical Context for Malignant Struma Ovarii

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MalaCards organs/tissues related to Malignant Struma Ovarii:

33
Thyroid, Liver, Endothelial, Neutrophil, Myeloid, Prostate, Skin

Animal Models for Malignant Struma Ovarii or affiliated genes

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MGI Mouse Phenotypes related to Malignant Struma Ovarii:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00036317.7HRAS, KRT19, LGALS3, RET, TG
2MP:00053797.7AFP, HRAS, KRT19, RET, TG
3MP:00020067.5AFP, HRAS, KRT19, LGALS3, RET

Publications for Malignant Struma Ovarii

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Articles related to Malignant Struma Ovarii:

(show top 50)    (show all 74)
idTitleAuthorsYear
1
Papillary thyroid cancer located in malignant struma ovarii with omentum metastasis: a case report and review of the literature. (26791568)
2016
2
Metastatic malignant struma ovarii with coexistence of Hashimoto's thyroiditis. (27224256)
2016
3
131I Therapy Using rhTSH Stimulation and Dosimetry in Metastatic Malignant Struma Ovarii. (24152665)
2014
4
Long-term survival in metastatic malignant struma ovarii treated with oral chemotherapy: A case report. (25364407)
2014
5
Treatment for malignant struma ovarii in the eyes of thyroid surgeons: a case report and study of Chinese cases reported in the literature. (25474425)
2014
6
The lack of consensus in management of malignant struma ovarii. (25539066)
2014
7
Malignant struma ovarii: a population-level analysis of a large series of 68 patients. (25375817)
2014
8
Two cases of malignant struma ovarii with metastasis to pelvic bone. (23391779)
2013
9
Malignant struma ovarii: a blinded study of 86 cases assessing which histologic features correlate with aggressive clinical behavior. (22288964)
2012
10
Malignant struma ovarii: the west of Scotland experience and review of literature with focus on postoperative management. (22883659)
2012
11
Unusual characteristics and fatal outcome of a malignant struma ovarii. Case report and literature review. (21531638)
2011
12
Laparoscopic excision of malignant struma ovarii and 1 year follow-up without further treatment. (21269611)
2011
13
Metastatic malignant struma ovarii. (21598816)
2011
14
Malignant struma ovarii. (20375218)
2010
15
Malignant struma ovarii: a case report. (20119594)
2010
16
Severe ophthalmopathy developing after treatment of coexisting malignant struma ovarii and Graves' disease. (19772400)
2009
17
Malignant struma ovarii: an analysis of 88 cases, including 27 with extraovarian spread. (19696610)
2009
18
Malignant struma ovarii with a focus of papillary thyroid cancer: a case report. (17882443)
2008
19
Malignant struma ovarii. (18560398)
2008
20
An unusual variant of malignant struma ovarii. (18678124)
2008
21
BRAF T1799A mutation occurring in a case of malignant struma ovarii. (17478764)
2007
22
Malignant struma ovarii: a case report and review of the literature. (17646728)
2007
23
Malignant struma ovarii mimic clear cell carcinoma. (14986024)
2005
24
Malignant struma ovarii with peritoneal implants and pelvic structures and liver metastases demonstrated by I-131 SPECT and low-dose CT. (16319636)
2005
25
Malignant struma ovarii: a case report and review of the literature. (15166470)
2004
26
Pseudo-Meigs' syndrome associated with malignant struma ovarii: a case report. (15262148)
2004
27
Pregnancy following treated malignant struma ovarii. (15524228)
2004
28
Case report: Malignant struma ovarii. (15038677)
2004
29
Benign and malignant struma ovarii: report of three cases and review of the literature. (17577264)
2002
30
Conservative therapy for malignant struma ovarii. A case report. (12497687)
2002
31
Malignant struma ovarii: report of a case and review of the literature. (12169779)
2002
32
Malignant struma ovarii with thyrotoxicosis. (11520159)
2001
33
Malignant struma ovarii: an unusual presentation. (11575860)
2001
34
Functioning liver metastases on an I-131 whole-body scan: a case of malignant struma ovarii. (10836696)
2000
35
Malignant struma ovarii: two case reports and a review of the literature. (10366477)
1999
36
Malignant struma ovarii: recurrence and response to treatment monitored by thyroglobulin levels. (9790800)
1998
37
Malignant struma ovarii. A case report and review of the literature. (9015705)
1997
38
Radiotherapy with iodine-131 in recurrent malignant struma ovarii. (9091289)
1997
39
Radiotherapy with iodine-131 in recurrent malignant struma ovarii. (8586108)
1996
40
Proliferative and histologically malignant struma ovarii: a clinicopathologic study of 54 cases. (8253550)
1993
41
Metastasis of malignant struma ovarii to the cranial vault during pregnancy. (8413886)
1993
42
Malignant struma ovarii: report of two cases and selected review of the literature. (2404159)
1990
43
Metastatic malignant struma ovarii presenting as paraparesis from a spinal metastasis. (2738669)
1989
44
Malignant struma ovarii. (2910784)
1989
45
Malignant struma ovarii treated by ovariectomy, thyroidectomy, and 131I administration. (3297279)
1987
46
Malignant struma ovarii. Light and electron microscopic study. (6821820)
1983
47
Malignant struma ovarii. A case report and literature review. (6887150)
1983
48
Malignant struma ovarii. (6628817)
1983
49
Benign and malignant struma ovarii. (580711)
1978
50
Malignant struma ovarii. (1004942)
1976

Variations for Malignant Struma Ovarii

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Expression for genes affiliated with Malignant Struma Ovarii

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Search GEO for disease gene expression data for Malignant Struma Ovarii.

Pathways for genes affiliated with Malignant Struma Ovarii

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Pathways related to Malignant Struma Ovarii according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
1
Show member pathways
9.2HRAS, RET
29.2HRAS, RET
39.2HRAS, RET
49.2HRAS, RET
59.2HRAS, RET

GO Terms for genes affiliated with Malignant Struma Ovarii

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Sources for Malignant Struma Ovarii

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet