MCID: MLG081
MIFTS: 46

Malignant Teratoma malady

Categories: Cancer diseases

Aliases & Classifications for Malignant Teratoma

Aliases & Descriptions for Malignant Teratoma:

Name: Malignant Teratoma 12 14
Primary Malignant Extragonadal Teratoma 12
Malignant Extragonadal Teratoma 12
Immature Extragonadal Teratoma 69
Teratoma, Malignant 69
Immature Teratoma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:5563
MeSH 42 D013724
NCIt 47 C4286 C8884
SNOMED-CT 64 189847002 19467007

Summaries for Malignant Teratoma

MalaCards based summary : Malignant Teratoma, also known as primary malignant extragonadal teratoma, is related to intermediate malignant teratoma and immature teratoma of ovary. An important gene associated with Malignant Teratoma is BAX (BCL2 Associated X, Apoptosis Regulator), and among its related pathways/superpathways are Apoptosis Pathway and Endometrial cancer. The drugs Etoposide and Cisplatin have been mentioned in the context of this disorder. Affiliated tissues include testis, thyroid and ovary, and related phenotypes are behavior/neurological and endocrine/exocrine gland

Related Diseases for Malignant Teratoma

Diseases in the Teratoma family:

Malignant Teratoma Adult Teratoma
Intermediate Malignant Teratoma

Diseases related to Malignant Teratoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 129)
id Related Disease Score Top Affiliating Genes
1 intermediate malignant teratoma 11.9
2 immature teratoma of ovary 11.0
3 malignant gastric teratoma 10.8
4 teratoma 10.6
5 twin-to-twin transfusion syndrome 10.3 BAX BCL2
6 anauxetic dysplasia 10.2 BAX BCL2
7 congenital absence of thigh and lower leg with foot present, bilateral 10.2 BAX BCL2
8 chromophil adenoma of the kidney 10.2 NKX2-1 TG
9 parachordoma 10.2 NKX2-1 TG
10 sphenoid sinus squamous cell carcinoma 10.2 AFP NKX2-1
11 vaginal adenosarcoma 10.2 BCL2 TP53
12 neuronopathy, distal hereditary motor, type viia 10.2 NKX2-1 TG
13 myositis 10.2 BCL2 SYP
14 pineal region yolk sac tumor 10.2 BCL2 SYP
15 uterine disease 10.2 AFP TP53
16 infiltrating renal pelvis transitional cell carcinoma 10.2 AFP SYP
17 proliferative glomerulonephritis 10.2 AFP SYP
18 thyroiditis 10.2
19 porokeratosis 10.2 NKX2-1 TP53
20 breast pericanalicular fibroadenoma 10.2 NKX2-1 TP53
21 spastic paraplegia 1 10.2 BCL2 TP53
22 ovarian germ cell teratoma 10.1 AFP SYP
23 bladder flat intraepithelial lesion 10.1 SYP TG
24 rectum leiomyoma 10.1 AFP SYP
25 nipple neoplasm 10.1 AFP SYP
26 adult botryoid rhabdomyosarcoma 10.1 AFP SYP
27 ovarian embryonal carcinoma 10.1 NKX2-1 TP53
28 villous adenocarcinoma 10.1 NKX2-1 SYP
29 spasmodic dysphonia 10.1 NKX2-1 SYP
30 medullomyoblastoma 10.1 AFP SYP
31 cavernous hemangioma of face 10.1 NKX2-1 SYP
32 cervical benign neoplasm 10.1 SYP TP53
33 pyloric antrum cancer 10.1 BAX BCL2 TP53
34 clear cell meningioma 10.1 SYP TP53
35 gallbladder papillomatosis 10.1 BAX BCL2 TP53
36 paternal uniparental disomy of chromosome 1 10.1 SYP TP53
37 vulvar benign neoplasm 10.1 SYP TP53
38 nasopharyngeal carcinoma 10.1 BAX BCL2 TP53
39 blood group incompatibility 10.1 SYP TP53
40 mast-cell sarcoma 10.1 SYP TP53
41 olfactory neuroblastoma 10.1 SYP TP53
42 bladder disease 10.1 BAX BCL2 TP53
43 cranial nerve disease 10.1 AFP NKX2-1
44 paraphimosis 10.1 SYP TP53
45 gastrinoma 10.1 AFP NKX2-1 TG
46 prostate cancer, hereditary, x-linked 1 10.1 AFP BAX TP53
47 glucosephosphate isomerase deficiency 10.1 BAX BCL2 TP53
48 childhood kidney cell carcinoma 10.1 AFP POU5F1
49 duodenal obstruction 10.1 NKX2-1 SYP
50 strabismus 10.1 SYP TG

Graphical network of the top 20 diseases related to Malignant Teratoma:



Diseases related to Malignant Teratoma

Symptoms & Phenotypes for Malignant Teratoma

MGI Mouse Phenotypes related to Malignant Teratoma:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 9.87 AFP BAX BCL2 NKX2-1 POU5F1 SYP
2 endocrine/exocrine gland MP:0005379 9.8 AFP BAX BCL2 NKX2-1 POU5F1 TG
3 neoplasm MP:0002006 9.55 AFP BAX BCL2 NKX2-1 TP53
4 nervous system MP:0003631 9.5 BAX BCL2 NKX2-1 POU5F1 SYP TG
5 reproductive system MP:0005389 9.1 AFP BAX BCL2 NKX2-1 POU5F1 TP53

Drugs & Therapeutics for Malignant Teratoma

Drugs for Malignant Teratoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 156)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Etoposide Approved Phase 4,Phase 3,Phase 2,Phase 1 33419-42-0 36462
2
Cisplatin Approved Phase 4,Phase 3,Phase 2,Phase 1 15663-27-1 84093 441203 2767
3
Carboplatin Approved Phase 4,Phase 3,Phase 2,Phase 1 41575-94-4 10339178 498142 38904
4
Ifosfamide Approved Phase 4,Phase 3,Phase 2,Phase 1 3778-73-2 3690
5
Mechlorethamine Approved Phase 4,Phase 3,Phase 1,Phase 2 51-75-2 4033
6 Alkylating Agents Phase 4,Phase 3,Phase 2,Phase 1
7 Topoisomerase Inhibitors Phase 4,Phase 3,Phase 2,Phase 1
8 Etoposide phosphate Phase 4,Phase 3,Phase 2,Phase 1
9 Isophosphamide mustard Phase 4,Phase 3,Phase 2,Phase 1
10 Antineoplastic Agents, Alkylating Phase 4,Phase 3,Phase 2,Phase 1
11 Antineoplastic Agents, Phytogenic Phase 4,Phase 3,Phase 2,Phase 1
12
Dexamethasone Approved, Investigational, Vet_approved Phase 3,Phase 2,Phase 1 50-02-2 5743
13
Vinblastine Approved Phase 3 865-21-4 13342 241903
14
Paclitaxel Approved, Vet_approved Phase 3,Phase 2,Phase 1 33069-62-4 36314
15
Cyclophosphamide Approved, Investigational Phase 3,Phase 2,Phase 1 50-18-0, 6055-19-2 2907
16
Bleomycin Approved Phase 3,Phase 2 11056-06-7 5360373
17
Oxaliplatin Approved, Investigational Phase 3,Phase 2 61825-94-3 5310940 9887054 6857599, 9887054 43805
18
Mesna Approved Phase 3,Phase 1,Phase 2 3375-50-6 598
19
Lenograstim Approved Phase 2, Phase 3, Phase 1 135968-09-1
20
Captopril Approved Phase 3 62571-86-2 44093
21
Amphotericin B Approved, Investigational Phase 3 1397-89-3 14956 5280965
22
Ribavirin Approved Phase 3 36791-04-5 37542
23
Fluconazole Approved Phase 3 86386-73-4 3365
24
Miconazole Approved, Investigational, Vet_approved Phase 3 22916-47-8 4189
25
Itraconazole Approved, Investigational Phase 3 84625-61-6 55283
26 Sodium thiosulfate Approved Phase 3,Phase 1
27
Palivizumab Approved, Investigational Phase 3 188039-54-5
28
Caspofungin Approved Phase 3 179463-17-3, 162808-62-0 468682 2826718
29
Succinylcholine Approved Phase 3 306-40-1 5314
30
Diphenhydramine Approved Phase 3 58-73-1, 147-24-0 3100
31
Promethazine Approved Phase 3 60-87-7 4927
32 Dexamethasone acetate Phase 3,Phase 2,Phase 1 1177-87-3
33 Adjuvants, Immunologic Phase 3,Phase 1,Phase 2
34 Albumin-Bound Paclitaxel Phase 3,Phase 2,Phase 1
35 Hormone Antagonists Phase 3,Phase 2,Phase 1
36 Dexamethasone 21-phosphate Phase 3,Phase 2,Phase 1
37 Hormones Phase 3,Phase 2,Phase 1
38 Peripheral Nervous System Agents Phase 3,Phase 2,Phase 1
39 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 3,Phase 2,Phase 1
40 Anti-Bacterial Agents Phase 3,Phase 2,Phase 1
41 Anti-Infective Agents Phase 3,Phase 1,Phase 2
42 Immunosuppressive Agents Phase 3,Phase 1,Phase 2
43 Liver Extracts Phase 3,Phase 2,Phase 1
44 Antimetabolites Phase 3,Phase 1,Phase 2
45 Antibiotics, Antitubercular Phase 3,Phase 2,Phase 1
46 Antimitotic Agents Phase 3,Phase 2,Phase 1
47 Antirheumatic Agents Phase 3,Phase 2,Phase 1
48 BB 1101 Phase 3,Phase 2,Phase 1
49 Antiviral Agents Phase 3,Phase 1,Phase 2
50 Hydroxyitraconazole Phase 3

Interventional clinical trials:

(show top 50) (show all 76)
id Name Status NCT ID Phase
1 Prospective Trial for the Diagnosis and Treatment of Intracranial Germ Cell Tumors Recruiting NCT01424839 Phase 4
2 Observation and/or Combination Chemotherapy After Surgery or Biopsy in Treating Young Patients With Extracranial Germ Cell Tumors Unknown status NCT00274950 Phase 3
3 Combination Chemotherapy in Treating Patients With Stage II or Stage III Germ Cell Tumors Unknown status NCT00104676 Phase 3
4 Combination Chemotherapy in Treating Men With Germ Cell Cancer Unknown status NCT00003643 Phase 2, Phase 3
5 Ribavirin With or Without Monoclonal Antibody Therapy in Treating Patients Who Develop RSV Pneumonia Following Peripheral Stem Cell Transplantation Completed NCT00014391 Phase 3
6 Caspofungin Acetate Compared With Amphotericin B Liposomal in Treating Patients With Persistent Fever and Neutropenia Following Cancer Treatment Completed NCT00008359 Phase 3
7 Captopril in Treating Patients Undergoing Bone Marrow or Stem Cell Transplantation Completed NCT00004230 Phase 3
8 Liposomal Amphotericin B in Treating Granulocytopenia and Persistent Unexplained Fever in Cancer Patients Completed NCT00003938 Phase 3
9 Itraconazole Compared With Fluconazole to Prevent Infections in Patients Undergoing Peripheral Stem Cell or Bone Marrow Transplantation Completed NCT00003883 Phase 3
10 Combination Chemotherapy With or Without Bone Marrow or Stem Cell Transplantation in Treating Men With Untreated Germ Cell Tumors Completed NCT00002596 Phase 3
11 Combination Chemotherapy With or Without Peripheral Stem Cell Transplant in Treating Men With Previously Untreated Germ Cell Cancer Completed NCT00003941 Phase 3
12 Sodium Thiosulfate in Preventing Hearing Loss in Young Patients Receiving Cisplatin for Newly Diagnosed Germ Cell Tumor, Hepatoblastoma, Medulloblastoma, Neuroblastoma, Osteosarcoma, or Other Malignancy Completed NCT00716976 Phase 3
13 Active Surveillance, Bleomycin, Carboplatin, Etoposide, or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumors Recruiting NCT03067181 Phase 3
14 Standard-Dose Combination Chemotherapy or High-Dose Combination Chemotherapy and Stem Cell Transplant in Treating Patients With Relapsed or Refractory Germ Cell Tumors Recruiting NCT02375204 Phase 3
15 Surgery and Combination Chemotherapy in Treating Children With Extracranial Germ Cell Tumors Active, not recruiting NCT00053352 Phase 3
16 Cisplatin and Ifosfamide Combined With Either Paclitaxel or Vinblastine in Treating Men With Progressive or Recurrent Metastatic Germ Cell Tumors Terminated NCT00072215 Phase 3
17 High-Dose Chemotherapy and Stem Cell Transplant in Treating Patients With Metastatic Germ Cell Tumors That Have Not Responded to First-Line Therapy Unknown status NCT01172912 Phase 2
18 Gemcitabine, Paclitaxel, Ifosfamide, and Cisplatin in Treating Patients With Progressive or Relapsed Metastatic Germ Cell Tumors Unknown status NCT00551122 Phase 1, Phase 2
19 Sunitinib in Treating Patients With Metastatic Germ Cell Tumors That Have Relapsed or Not Responded to Treatment Completed NCT00453310 Phase 2
20 Combination Chemotherapy and Pegfilgrastim in Treating Patients With Previously Untreated Germ Cell Tumors Completed NCT00470366 Phase 2
21 Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Relapsed Germ Cell Cancer Completed NCT00002931 Phase 2
22 Combination Chemotherapy in Treating Male Patients With Germ Cell Tumors Completed NCT00301782 Phase 2
23 Combination Chemotherapy and Pegfilgrastim in Treating Men With Metastatic Germ Cell Tumors Completed NCT00453232 Phase 2
24 Paclitaxel, Ifosfamide, and Carboplatin Followed By Autologous Stem Cell Transplant in Treating Patients With Germ Cell Tumors That Did Not Respond to Cisplatin Completed NCT00423852 Phase 1, Phase 2
25 Immunotherapy in Treating Patients Who Are Undergoing Bone Marrow or Peripheral Stem Cell Transplantation Completed NCT00002673 Phase 2
26 Beclomethasone in Treating Patients With Graft-Versus-Host Disease of the Esophagus, Stomach, Small Intestine, or Colon Completed NCT00010283 Phase 1, Phase 2
27 Interleukin-11 Plus Filgrastim Prior to Peripheral Stem Cell Transplantation in Patients With Non-Hodgkin's Lymphoma, Hodgkin's Disease, Breast Cancer, or Other Solid Tumors Completed NCT00004157 Phase 2
28 Lymphocyte Infusion in Treating Patients With Relapsed Cancer After Bone Marrow or Peripheral Stem Cell Transplantation Completed NCT00003887 Phase 2
29 Biological Therapy Following Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Cancer Completed NCT00003408 Phase 2
30 Ixabepilone in Treating Patients With Advanced Cisplatin-Refractory Germ Cell Tumors Completed NCT00070096 Phase 2
31 Combination Chemotherapy in Treating Children With Non-testicular Malignant Germ Cell Tumors Completed NCT00002489 Phase 2
32 Combination Chemotherapy Plus Amifostine in Treating Children With Malignant Germ Cell Tumors Completed NCT00003811 Phase 2
33 Temozolomide Followed by Radiation Therapy in Treating Children With Newly Diagnosed Malignant CNS Tumors Completed NCT00005955 Phase 2
34 Oxaliplatin in Treating Young Patients With Recurrent Solid Tumors That Have Not Responded to Previous Treatment Completed NCT00091182 Phase 2
35 Paclitaxel, Ifosfamide, and Cisplatin in Treating Patients With Metastatic Testicular Cancer Completed NCT00004077 Phase 2
36 High-Dose Thiotepa Plus Peripheral Stem Cell Transplantation in Treating Patients With Refractory Solid Tumors Completed NCT00003173 Phase 2
37 Arsenic Trioxide in Treating Patients With Advanced Neuroblastoma or Other Childhood Solid Tumors Completed NCT00024258 Phase 2
38 Neoadjuvant Chemotherapy With or Without Second-Look Surgery Followed by Radiation Therapy With or Without Peripheral Stem Cell Transplantation in Treating Patients With Intracranial Germ Cell Tumors Completed NCT00047320 Phase 2
39 PHASE II TRIAL OF THE CYCLIN-DEPEDENT KINASE INHIBITOR PD 0332991 IN PATIENTS WITH CANCER Recruiting NCT01037790 Phase 2
40 Autologous Peripheral Blood Stem Cell Transplant for Germ Cell Tumors Recruiting NCT00432094 Phase 2
41 Phase 2 Study of Alisertib Therapy for Rhabdoid Tumors Recruiting NCT02114229 Phase 2
42 Nivolumab and Ipilimumab in Treating Patients With Rare Tumors Recruiting NCT02834013 Phase 2
43 Dasatinib, Ifosfamide, Carboplatin, and Etoposide in Treating Young Patients With Metastatic or Recurrent Malignant Solid Tumors Active, not recruiting NCT00788125 Phase 1, Phase 2
44 Palifosfamide in Treating Patients With Recurrent Germ Cell Tumors Terminated NCT01808534 Phase 2
45 Peripheral Stem Cell Transplantation Plus Chemotherapy in Treating Patients With Malignant Solid Tumors Unknown status NCT00007813 Phase 1
46 Ipilimumab After Allogeneic Stem Cell Transplant in Treating Patients With Persistent or Progressive Cancer Completed NCT00060372 Phase 1
47 Interleukin-12 in Treating Patients With Hematologic Cancers or Solid Tumors Completed NCT00003107 Phase 1
48 Liposomal Doxorubicin in Treating Children With Refractory Solid Tumors Completed NCT00019630 Phase 1
49 Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Infants With Malignant Brain or Spinal Cord Tumors Completed NCT00003141 Phase 1
50 Vorinostat and Bortezomib in Treating Young Patients With Refractory or Recurrent Solid Tumors, Including Central Nervous System Tumors and Lymphoma Completed NCT00994500 Phase 1

Search NIH Clinical Center for Malignant Teratoma

Genetic Tests for Malignant Teratoma

Anatomical Context for Malignant Teratoma

MalaCards organs/tissues related to Malignant Teratoma:

39
Testis, Thyroid, Ovary, Lung, Heart, Brain, Pineal

Publications for Malignant Teratoma

Articles related to Malignant Teratoma:

(show top 50) (show all 153)
id Title Authors Year
1
Malignant teratoma in Klippel-Feil syndrome: a case report and review of the literature. ( 26438353 )
2015
2
Pathology in practice. Malignant teratoma of the left ovary of a mouse. ( 24984129 )
2014
3
Chemoresponsive liver hemangioma in a patient with metastatic malignant teratoma. ( 25168798 )
2014
4
Primary malignant teratoma of lung: report of a case and review of the literature. ( 22180529 )
2012
5
Unusual presentation of fetus-in-fetu mimicking malignant teratoma. ( 21922882 )
2011
6
[Inhibitory effect of matrine on proliferation of human ovary malignant teratoma cell line PA-1 in vitro]. ( 20929131 )
2010
7
What is your diagnosis? Peritoneal fluid from a 1-year-old female German Shepherd dog. Malignant teratoma. ( 20561318 )
2010
8
Malignant teratoma of the thyroid in a pregnant woman. ( 20637432 )
2010
9
Primary malignant teratoma of the thyroid in a child with nodal metastases. ( 19332924 )
2009
10
Case report: malignant teratoma of the uterine corpus. ( 19538751 )
2009
11
Successful pregnancy after treatment for ovarian malignant teratoma with growing teratoma syndrome. ( 19152879 )
2009
12
Metastatic malignant teratoma arising from mediastinal nonseminomatous germ cell tumor: a case report. ( 18472634 )
2008
13
Cystic malignant teratoma with early recurrence after intraoperative spillage. ( 19022022 )
2008
14
Malignant teratoma vs. carcinoma with teratomatous elements, rather than metaplastic carcinoma. ( 17097879 )
2007
15
Primary malignant teratoma with a primitive neuroectodermal tumor component in thyroid gland: a case report. ( 17596674 )
2007
16
Malignant teratoma 32 years after treatment of germ cell tumor confined to testis. ( 16566989 )
2006
17
Malignant teratoma of the thyroid: case report. ( 17199442 )
2006
18
Case report: malignant teratoma of the sinonasal tract. ( 15368065 )
2005
19
Gamma mode of infiltration associated with poor prognosis in malignant teratoma of the ovary: A case report. ( 15922442 )
2005
20
Thyroid carcinoma arising from a sacrococcygeal mass: a malignant teratoma? ( 15307946 )
2004
21
Malignant teratoma of the thyroid: aggressive chemoradiation therapy is required after surgery. ( 12804109 )
2003
22
Malignant teratoma of the orbit: a clinicopathological study of a case. ( 14685907 )
2003
23
Malignant teratoma of the thyroid with primitive neuroepithelial and mesenchymal sarcomatous components. ( 11598856 )
2001
24
Malignant teratoma of the medulla oblongata in an adult male. ( 11810399 )
2001
25
Malignant teratoma of the thyroid with predominantly neuroepithelial differentiation. Fine needle aspiration cytologic, histologic and immunocytochemical features of a case. ( 10833994 )
2000
26
Malignant teratoma of the thyroid: review of literature and report of a case. ( 10758996 )
2000
27
Malignant teratoma of the lung. ( 10665772 )
1999
28
Theriogenology question of the month. Malignant teratoma of the ovary. ( 10101408 )
1999
29
Primary malignant teratoma of the thyroid gland: report and discussion of two cases. ( 9744468 )
1998
30
Immature malignant teratoma of the thyroid gland. ( 9646244 )
1998
31
Primary cervical malignant teratoma with a rib metastasis in an adult: five-year survival after surgery and chemotherapy. A case report with a review of the literature. ( 9818077 )
1998
32
Malignant teratoma of the testis presenting with bilateral inguinal lymphadenopathy and diagnosed by fine needle aspiration (FNA). ( 9134338 )
1997
33
Retroperitoneal surgery: its wider role in the management of malignant teratoma. ( 8777620 )
1996
34
Primary pulmonary malignant teratoma with yolk sac element associated with hematologic neoplasia. ( 8833994 )
1996
35
Case report: malignant teratoma in the thyroid gland. ( 8983598 )
1996
36
Retroperitoneal malignant teratoma. A case report. ( 8935151 )
1995
37
Malignant teratoma of the testicle: diagnosis suggested by preoperative ultrasonography. ( 7502125 )
1995
38
Malignant teratoma undifferentiated (MTU) metastasising solely as differentiated teratoma: implications for the aetiology of residual differentiated disease following successful chemotherapy. ( 8562181 )
1995
39
Carcinoma in situ of the testis followed by an overt malignant teratoma of the testis within 12 months. ( 7980264 )
1994
40
Ifosfamide and carboplatin combined with 41.8 degrees C whole-body hyperthermia in patients with refractory sarcoma and malignant teratoma. ( 7923163 )
1994
41
Mediastinal malignant teratoma and acute myeloid leukemia in a patient with Klinefelter's syndrome--comparison of DNA content in the two malignancies. ( 7946452 )
1994
42
Prenatal diagnosis of intracranial teratoma. Prolonged survival after resection of a malignant teratoma diagnosed prenatally by ultrasound: a case report and literature review. ( 8382936 )
1993
43
Resection of an intracardiac metastasis from malignant teratoma of the testis. ( 8267441 )
1993
44
MRI detection of ruptured malignant teratoma in the third ventricle. ( 8492886 )
1993
45
Management of malignant teratoma: does referral to a specialist unit matter? ( 8096954 )
1993
46
Malignant teratoma of the lung with lymph node metastasis of the ectodermal compartment: a case report. ( 8318068 )
1993
47
Malignant teratoma arising in a dysgenetic gonad. ( 7690731 )
1993
48
Extragonadal malignant teratoma of the foot. ( 1473840 )
1992
49
Suprasellar malignant teratoma with 11-year survival--case report. ( 1383861 )
1992
50
Pilot study to evaluate impact of a policy of adjuvant chemotherapy for high risk stage 1 malignant teratoma on overall relapse rate of stage 1 cancer patients. ( 1279211 )
1992

Variations for Malignant Teratoma

Expression for Malignant Teratoma

Search GEO for disease gene expression data for Malignant Teratoma.

Pathways for Malignant Teratoma

Pathways related to Malignant Teratoma according to GeneCards Suite gene sharing:

(show all 24)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
12.21 BAX BCL2 TP53
2
Show member pathways
12.13 BAX BCL2 TP53
3
Show member pathways
12.03 BAX BCL2 TP53
4 11.9 BAX BCL2 TP53
5 11.86 BAX BCL2 TP53
6 11.82 BAX BCL2 TP53
7
Show member pathways
11.76 BAX BCL2 TP53
8 11.73 BAX BCL2 TP53
9 11.69 BAX BCL2 TP53
10
Show member pathways
11.67 BAX BCL2 TP53
11 11.46 AFP BAX TP53
12 11.38 AFP BAX BCL2 TP53
13 11.36 BAX BCL2 TP53
14 11.2 BAX TP53
15 11.17 BAX TP53
16 11.14 BAX BCL2 TP53
17 11.1 BAX BCL2
18 11.03 BAX BCL2
19 10.99 BAX BCL2 TP53
20 10.93 BAX BCL2
22 10.83 BAX BCL2
23 10.4 BAX BCL2
24
Show member pathways
10.14 BAX BCL2 TP53

GO Terms for Malignant Teratoma

Cellular components related to Malignant Teratoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 pore complex GO:0046930 8.62 BAX BCL2

Biological processes related to Malignant Teratoma according to GeneCards Suite gene sharing:

(show all 30)
id Name GO ID Score Top Affiliating Genes
1 regulation of apoptotic process GO:0042981 9.81 BAX BCL2 TP53
2 neuron apoptotic process GO:0051402 9.65 BAX BCL2
3 cellular response to glucose starvation GO:0042149 9.64 BCL2 TP53
4 intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 9.63 BAX TP53
5 extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 9.63 BAX BCL2
6 negative regulation of fibroblast proliferation GO:0048147 9.62 BAX TP53
7 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress GO:0070059 9.62 BAX BCL2
8 positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway GO:1900740 9.61 BCL2 TP53
9 homeostasis of number of cells within a tissue GO:0048873 9.61 BAX BCL2
10 regulation of mitochondrial membrane potential GO:0051881 9.6 BAX BCL2
11 extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 9.59 BAX BCL2
12 intrinsic apoptotic signaling pathway GO:0097193 9.58 BAX TP53
13 positive regulation of release of cytochrome c from mitochondria GO:0090200 9.58 BAX TP53
14 cell aging GO:0007569 9.57 BCL2 TP53
15 thyroid gland development GO:0030878 9.56 NKX2-1 TG
16 apoptotic mitochondrial changes GO:0008637 9.55 BAX BCL2
17 release of cytochrome c from mitochondria GO:0001836 9.54 BAX BCL2
18 B cell homeostasis GO:0001782 9.52 BAX BCL2
19 negative regulation of apoptotic signaling pathway GO:2001234 9.51 BAX BCL2
20 cellular response to organic substance GO:0071310 9.5 BAX BCL2 SYP
21 endoplasmic reticulum calcium ion homeostasis GO:0032469 9.49 BAX BCL2
22 positive regulation of protein oligomerization GO:0032461 9.48 BAX TP53
23 regulation of mitochondrial membrane permeability GO:0046902 9.46 BCL2 TP53
24 regulation of protein heterodimerization activity GO:0043497 9.43 BAX BCL2
25 regulation of protein homodimerization activity GO:0043496 9.4 BAX BCL2
26 leukocyte homeostasis GO:0001776 9.37 BAX BCL2
27 regulation of nitrogen utilization GO:0006808 9.26 BAX BCL2
28 positive regulation of developmental pigmentation GO:0048087 9.16 BAX BCL2
29 response to gamma radiation GO:0010332 9.13 BAX BCL2 TP53
30 positive regulation of intrinsic apoptotic signaling pathway GO:2001244 8.8 BAX BCL2 TP53

Molecular functions related to Malignant Teratoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 protein phosphatase 2A binding GO:0051721 9.16 BCL2 TP53
2 channel activity GO:0015267 8.96 BAX BCL2
3 BH3 domain binding GO:0051434 8.62 BAX BCL2

Sources for Malignant Teratoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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