MCID: MLG081
MIFTS: 43

Malignant Teratoma

Categories: Cancer diseases

Aliases & Classifications for Malignant Teratoma

MalaCards integrated aliases for Malignant Teratoma:

Name: Malignant Teratoma 12 14
Primary Malignant Extragonadal Teratoma 12
Malignant Extragonadal Teratoma 12
Immature Extragonadal Teratoma 69
Teratoma, Malignant 69
Immature Teratoma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:5563
MeSH 42 D013724
NCIt 47 C4286 C8884
SNOMED-CT 64 189847002 19467007

Summaries for Malignant Teratoma

MalaCards based summary : Malignant Teratoma, also known as primary malignant extragonadal teratoma, is related to mature teratoma and intermediate malignant teratoma. An important gene associated with Malignant Teratoma is AFP (Alpha Fetoprotein), and among its related pathways/superpathways are Direct p53 effectors and Integrated Cancer Pathway. The drugs Carboplatin and Cisplatin have been mentioned in the context of this disorder. Affiliated tissues include testis, thyroid and bone, and related phenotypes are behavior/neurological and growth/size/body region

Related Diseases for Malignant Teratoma

Diseases in the Teratoma family:

Malignant Teratoma Adult Teratoma
Intermediate Malignant Teratoma

Diseases related to Malignant Teratoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 175)
id Related Disease Score Top Affiliating Genes
1 mature teratoma 24.8 AFP ANO6 BAX BCL2 ENO2 NKX2-1
2 intermediate malignant teratoma 11.9
3 immature teratoma of ovary 11.0
4 malignant gastric teratoma 10.8
5 pulmonary hypertension 10.7 BAX BCL2
6 congenital hereditary facial paralysis-variable hearing loss syndrome 10.7 BAX BCL2
7 pylorus cancer 10.7 BAX BCL2
8 metaphyseal dysplasia without hypotrichosis 10.6 BAX BCL2
9 teratoma 10.6
10 hydromyelia 10.6 BCL2 ENO2
11 nodular medulloblastoma 10.6 AFP ENO2
12 benign pericardial teratoma 10.5 AFP ENO2
13 pulmonary valve disease 10.5 BAX BCL2
14 ovarian fetiform teratoma 10.5 BCL2 SYP
15 parietal lobe neoplasm 10.5 ENO2 TG
16 mediastinum synovial sarcoma 10.5 AFP TG
17 tibia absent polydactyly arachnoid cyst 10.5 NKX2-1 TG
18 cerebellar vermis medulloblastoma 10.5 AFP SYP
19 pulmonary neuroendocrine tumor 10.5 SYP TG
20 panhypophysitis 10.4 NKX2-1 TG
21 rete ovarii cystadenofibroma 10.4 AFP SYP
22 2q31.1 microdeletion syndrome 10.4 ENO2 SYP
23 parachordoma 10.4 NKX2-1 TG
24 diphtheria 10.4 ENO2 TG
25 retinitis pigmentosa 10.4 BAX BCL2
26 aflatoxins-related hepatocellular carcinoma 10.4 AFP SYP
27 hypothyroidism, congenital, due to thyroid dysgenesis or hypoplasia 10.4 NKX2-1 TG
28 pneumothorax 10.4 AFP SYP
29 ampulla of vater small cell carcinoma 10.4 ENO2 SYP
30 tricuspid valve insufficiency 10.4 AFP SYP
31 situs inversus totalis with cystic dysplasia of kidneys and pancreas 10.4 ENO2 SYP
32 childhood choriocarcinoma of the ovary 10.4 ENO2 SYP
33 glomus tumor 10.4 ENO2 SYP
34 osteoblastoma 10.4 ENO2 SYP
35 bronchus adenoma 10.4 ENO2 SYP
36 cystitis cystica 10.4 ENO2 SYP
37 pemphigus foliaceus 10.4 ENO2 SYP
38 gallbladder adenocarcinoma 10.4 ENO2 SYP
39 chondroid chordoma 10.4 ENO2 SYP
40 brain glioma 10.4 ENO2 SYP
41 mast cell neoplasm 10.4 ENO2 SYP
42 hair disease 10.4 ENO2 SYP
43 cauda equina intradural extramedullary astrocytoma 10.4 ENO2 SYP
44 congenital bile acid synthesis defect 10.4 AFP NKX2-1
45 rh isoimmunization 10.4 ENO2 SYP
46 pleomorphic xanthoastrocytoma 10.4 ENO2 SYP
47 thymus large cell carcinoma 10.4 ENO2 SYP
48 cauda equina neoplasm 10.4 ENO2 SYP
49 axonal neuropathy 10.4 ENO2 SYP
50 childhood choroid plexus cancer 10.4 ENO2 SYP

Graphical network of the top 20 diseases related to Malignant Teratoma:



Diseases related to Malignant Teratoma

Symptoms & Phenotypes for Malignant Teratoma

MGI Mouse Phenotypes related to Malignant Teratoma:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 9.7 AFP BAX BCL2 ENO2 NKX2-1 SALL4
2 growth/size/body region MP:0005378 9.5 ANO6 BAX BCL2 ENO2 NKX2-1 SALL4
3 nervous system MP:0003631 9.17 TG BAX BCL2 ENO2 NKX2-1 SALL4

Drugs & Therapeutics for Malignant Teratoma

Drugs for Malignant Teratoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 125)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Carboplatin Approved Phase 4,Phase 3,Phase 2,Phase 1 41575-94-4 10339178 498142 38904
2
Cisplatin Approved Phase 4,Phase 3,Phase 2,Phase 1 15663-27-1 84093 441203 2767
3
Etoposide Approved Phase 4,Phase 3,Phase 2,Phase 1 33419-42-0 36462
4
Ifosfamide Approved Phase 4,Phase 3,Phase 2,Phase 1 3778-73-2 3690
5
Mechlorethamine Approved Phase 4,Phase 3,Phase 2,Phase 1 51-75-2 4033
6 Alkylating Agents Phase 4,Phase 3,Phase 2,Phase 1
7 Antineoplastic Agents, Phytogenic Phase 4,Phase 3,Phase 2,Phase 1
8 Etoposide phosphate Phase 4,Phase 3,Phase 2,Phase 1
9 Isophosphamide mustard Phase 4,Phase 3,Phase 2,Phase 1
10 Topoisomerase Inhibitors Phase 4,Phase 3,Phase 2,Phase 1
11
Bleomycin Approved Phase 3,Phase 2 11056-06-7 5360373
12
Vinblastine Approved Phase 3 865-21-4 13342 241903
13
Oxaliplatin Approved, Investigational Phase 3 61825-94-3 5310940 9887054 43805 6857599
14
Paclitaxel Approved, Vet_approved Phase 3,Phase 2,Phase 1 33069-62-4 36314
15
Lenograstim Approved Phase 2, Phase 3,Phase 1 135968-09-1
16
Cyclophosphamide Approved, Investigational Phase 3,Phase 2,Phase 1 50-18-0, 6055-19-2 2907
17
Palivizumab Approved, Investigational Phase 3 188039-54-5
18
Ribavirin Approved Phase 3 36791-04-5 37542
19
Amphotericin B Approved, Investigational Phase 3 1397-89-3 14956 5280965
20
Caspofungin Approved Phase 3 179463-17-3, 162808-62-0 468682 2826718
21
Miconazole Approved, Investigational, Vet_approved Phase 3 22916-47-8 4189
22
Captopril Approved Phase 3 62571-86-2 44093
23
Fluconazole Approved Phase 3 86386-73-4 3365
24
Itraconazole Approved, Investigational Phase 3 84625-61-6 55283
25 Anti-Bacterial Agents Phase 3,Phase 2,Phase 1
26 Antibiotics, Antitubercular Phase 3,Phase 2,Phase 1
27 Antimitotic Agents Phase 3,Phase 2,Phase 1
28 Albumin-Bound Paclitaxel Phase 3,Phase 2,Phase 1
29 Antirheumatic Agents Phase 3,Phase 2,Phase 1
30 Immunosuppressive Agents Phase 3,Phase 1,Phase 2
31 Hormone Antagonists Phase 3,Phase 2,Phase 1
32 Hormones Phase 3,Phase 2,Phase 1
33 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 3,Phase 2,Phase 1
34 Antibodies Phase 3,Phase 1
35 Antibodies, Monoclonal Phase 3,Phase 1
36 Anti-Infective Agents Phase 3,Phase 2,Phase 1
37 Antimetabolites Phase 3,Phase 2
38 Antiviral Agents Phase 3,Phase 2,Phase 1
39 Immunoglobulins Phase 3,Phase 1
40 Antifungal Agents Phase 3
41 Antiparasitic Agents Phase 3
42 Antiprotozoal Agents Phase 3
43 Echinocandins Phase 3
44 Liposomal amphotericin B Phase 3
45 Angiotensin-Converting Enzyme Inhibitors Phase 3
46 Antihypertensive Agents Phase 3
47 HIV Protease Inhibitors Phase 3
48
protease inhibitors Phase 3
49 Cytochrome P-450 CYP2C9 Inhibitors Phase 3
50 Cytochrome P-450 CYP3A Inhibitors Phase 3

Interventional clinical trials:

(show all 46)

id Name Status NCT ID Phase Drugs
1 Prospective Trial for the Diagnosis and Treatment of Intracranial Germ Cell Tumors Recruiting NCT01424839 Phase 4 Carboplatin, Etoposide, Ifosfamide;Cisplatin, etoposide, Ifosfamide (standard);Cisplatin, Etoposide, Ifosfamide (high dose)
2 Observation and/or Combination Chemotherapy After Surgery or Biopsy in Treating Young Patients With Extracranial Germ Cell Tumors Unknown status NCT00274950 Phase 3 carboplatin;cisplatin;etoposide;ifosfamide;vinblastine sulfate
3 Combination Chemotherapy in Treating Patients With Stage II or Stage III Germ Cell Tumors Unknown status NCT00104676 Phase 3 cisplatin;etoposide;ifosfamide;oxaliplatin;paclitaxel
4 Combination Chemotherapy in Treating Men With Germ Cell Cancer Unknown status NCT00003643 Phase 2, Phase 3 cisplatin;etoposide;paclitaxel
5 Ribavirin With or Without Monoclonal Antibody Therapy in Treating Patients Who Develop RSV Pneumonia Following Peripheral Stem Cell Transplantation Completed NCT00014391 Phase 3 ribavirin
6 Caspofungin Acetate Compared With Amphotericin B Liposomal in Treating Patients With Persistent Fever and Neutropenia Following Cancer Treatment Completed NCT00008359 Phase 3 caspofungin acetate;liposomal amphotericin B
7 Captopril in Treating Patients Undergoing Bone Marrow or Stem Cell Transplantation Completed NCT00004230 Phase 3 captopril;cyclophosphamide
8 Liposomal Amphotericin B in Treating Granulocytopenia and Persistent Unexplained Fever in Cancer Patients Completed NCT00003938 Phase 3 liposomal amphotericin B
9 Itraconazole Compared With Fluconazole to Prevent Infections in Patients Undergoing Peripheral Stem Cell or Bone Marrow Transplantation Completed NCT00003883 Phase 3 fluconazole;itraconazole
10 Active Surveillance, Bleomycin, Carboplatin, Etoposide, or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumors Recruiting NCT03067181 Phase 3 Bleomycin;Carboplatin;Cisplatin;Etoposide
11 Surgery and Combination Chemotherapy in Treating Children With Extracranial Germ Cell Tumors Active, not recruiting NCT00053352 Phase 3 cisplatin;etoposide
12 Cisplatin and Ifosfamide Combined With Either Paclitaxel or Vinblastine in Treating Men With Progressive or Recurrent Metastatic Germ Cell Tumors Terminated NCT00072215 Phase 3 cisplatin;ifosfamide;paclitaxel;vinblastine
13 High-Dose Chemotherapy and Stem Cell Transplant in Treating Patients With Metastatic Germ Cell Tumors That Have Not Responded to First-Line Therapy Unknown status NCT01172912 Phase 2 carboplatin;cisplatin;dexamethasone;etoposide;ifosfamide
14 Sunitinib in Treating Patients With Metastatic Germ Cell Tumors That Have Relapsed or Not Responded to Treatment Completed NCT00453310 Phase 2 sunitinib malate
15 Combination Chemotherapy and Pegfilgrastim in Treating Patients With Previously Untreated Germ Cell Tumors Completed NCT00470366 Phase 2 cisplatin;ifosfamide;paclitaxel
16 Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Relapsed Germ Cell Cancer Completed NCT00002931 Phase 2 carboplatin;etoposide;ifosfamide;paclitaxel
17 Combination Chemotherapy in Treating Male Patients With Germ Cell Tumors Completed NCT00301782 Phase 2 carboplatin;cisplatin;etoposide phosphate;vincristine sulfate
18 Combination Chemotherapy and Pegfilgrastim in Treating Men With Metastatic Germ Cell Tumors Completed NCT00453232 Phase 2 cisplatin;etoposide
19 Paclitaxel, Ifosfamide, and Carboplatin Followed By Autologous Stem Cell Transplant in Treating Patients With Germ Cell Tumors That Did Not Respond to Cisplatin Completed NCT00423852 Phase 1, Phase 2 carboplatin;ifosfamide;paclitaxel
20 Immunotherapy in Treating Patients Who Are Undergoing Bone Marrow or Peripheral Stem Cell Transplantation Completed NCT00002673 Phase 2
21 Beclomethasone in Treating Patients With Graft-Versus-Host Disease of the Esophagus, Stomach, Small Intestine, or Colon Completed NCT00010283 Phase 1, Phase 2 beclomethasone dipropionate
22 Interleukin-11 Plus Filgrastim Prior to Peripheral Stem Cell Transplantation in Patients With Non-Hodgkin's Lymphoma, Hodgkin's Disease, Breast Cancer, or Other Solid Tumors Completed NCT00004157 Phase 2
23 Lymphocyte Infusion in Treating Patients With Relapsed Cancer After Bone Marrow or Peripheral Stem Cell Transplantation Completed NCT00003887 Phase 2
24 Biological Therapy Following Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Cancer Completed NCT00003408 Phase 2
25 Ixabepilone in Treating Patients With Advanced Cisplatin-Refractory Germ Cell Tumors Completed NCT00070096 Phase 2 ixabepilone
26 Combination Chemotherapy in Treating Children With Non-testicular Malignant Germ Cell Tumors Completed NCT00002489 Phase 2 carboplatin;cyclophosphamide;doxorubicin hydrochloride;etoposide;leucovorin calcium;methotrexate;vincristine sulfate
27 Combination Chemotherapy Plus Amifostine in Treating Children With Malignant Germ Cell Tumors Completed NCT00003811 Phase 2 amifostine trihydrate;cisplatin;etoposide
28 Temozolomide Followed by Radiation Therapy in Treating Children With Newly Diagnosed Malignant CNS Tumors Completed NCT00005955 Phase 2 temozolomide
29 PHASE II TRIAL OF THE CYCLIN-DEPEDENT KINASE INHIBITOR PD 0332991 IN PATIENTS WITH CANCER Recruiting NCT01037790 Phase 2 PD-0332991
30 Autologous Peripheral Blood Stem Cell Transplant for Germ Cell Tumors Recruiting NCT00432094 Phase 2 carboplatin;etoposide;ifosfamide;paclitaxel;thiotepa;Mesna
31 Phase 2 Study of Alisertib Therapy for Rhabdoid Tumors Recruiting NCT02114229 Phase 2 alisertib;methotrexate;cisplatin;carboplatin;cyclophosphamide;etoposide;topotecan;vincristine
32 Dasatinib, Ifosfamide, Carboplatin, and Etoposide in Treating Young Patients With Metastatic or Recurrent Malignant Solid Tumors Active, not recruiting NCT00788125 Phase 1, Phase 2 carboplatin;dasatinib;etoposide phosphate;ifosfamide
33 Peripheral Stem Cell Transplantation Plus Chemotherapy in Treating Patients With Malignant Solid Tumors Unknown status NCT00007813 Phase 1 carboplatin;cyclophosphamide;etoposide
34 Ipilimumab After Allogeneic Stem Cell Transplant in Treating Patients With Persistent or Progressive Cancer Completed NCT00060372 Phase 1 ipilimumab;therapeutic allogeneic lymphocytes
35 Interleukin-12 in Treating Patients With Hematologic Cancers or Solid Tumors Completed NCT00003107 Phase 1
36 Liposomal Doxorubicin in Treating Children With Refractory Solid Tumors Completed NCT00019630 Phase 1 doxorubicin HCl liposome
37 Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Infants With Malignant Brain or Spinal Cord Tumors Completed NCT00003141 Phase 1 carboplatin;cisplatin;cyclophosphamide;etoposide;thiotepa;vincristine sulfate
38 Acetylcysteine, Mannitol, Combination Chemotherapy, and Sodium Thiosulfate in Treating Children With Malignant Brain Tumors Terminated NCT00238173 Phase 1 acetylcysteine;carboplatin;cyclophosphamide;etoposide phosphate;mannitol;sodium thiosulfate
39 Etoposide, Carboplatin, and Bleomycin in Treating Young Patients Undergoing Surgery For Malignant Germ Cell Tumors Unknown status NCT00276718 carboplatin;etoposide
40 Anterior Mediastinum Teratoma: A Case Report Completed NCT00836121
41 Acupuncture in Treating Mucositis-Related Pain Caused by Chemotherapy in Patients Undergoing Stem Cell Transplantation Completed NCT00060021
42 Standard Follow-up Compared With Extended Follow-up in Treating Patients Who Have Undergone Stem Cell Transplantation for Cancer Completed NCT00049465
43 Combination Chemotherapy in Treating Children With Newly Diagnosed Malignant Germ Cell Tumors Completed NCT00066482 cisplatin;cyclophosphamide;etoposide
44 CT Scans in Treating Patients With Stage I Testicular Cancer After Undergoing Orchiectomy Completed NCT00003420
45 DNA Analysis in Samples From Younger Patients With Germ Cell Tumors and Their Parents or Siblings Recruiting NCT01434355
46 Biomarker Study in Samples From Patients With Malignant Rhabdoid Tumor of the Kidney or Atypical Teratoid Rhabdoid Tumor Withdrawn NCT01453465

Search NIH Clinical Center for Malignant Teratoma

Genetic Tests for Malignant Teratoma

Anatomical Context for Malignant Teratoma

MalaCards organs/tissues related to Malignant Teratoma:

39
Testis, Thyroid, Bone, Bone Marrow, Ovary, Brain, Colon

Publications for Malignant Teratoma

Articles related to Malignant Teratoma:

(show top 50) (show all 153)
id Title Authors Year
1
Malignant teratoma in Klippel-Feil syndrome: a case report and review of the literature. ( 26438353 )
2015
2
Pathology in practice. Malignant teratoma of the left ovary of a mouse. ( 24984129 )
2014
3
Chemoresponsive liver hemangioma in a patient with metastatic malignant teratoma. ( 25168798 )
2014
4
Primary malignant teratoma of lung: report of a case and review of the literature. ( 22180529 )
2012
5
Unusual presentation of fetus-in-fetu mimicking malignant teratoma. ( 21922882 )
2011
6
Malignant teratoma of the thyroid in a pregnant woman. ( 20637432 )
2010
7
What is your diagnosis? Peritoneal fluid from a 1-year-old female German Shepherd dog. Malignant teratoma. ( 20561318 )
2010
8
[Inhibitory effect of matrine on proliferation of human ovary malignant teratoma cell line PA-1 in vitro]. ( 20929131 )
2010
9
Primary malignant teratoma of the thyroid in a child with nodal metastases. ( 19332924 )
2009
10
Case report: malignant teratoma of the uterine corpus. ( 19538751 )
2009
11
Successful pregnancy after treatment for ovarian malignant teratoma with growing teratoma syndrome. ( 19152879 )
2009
12
Cystic malignant teratoma with early recurrence after intraoperative spillage. ( 19022022 )
2008
13
Metastatic malignant teratoma arising from mediastinal nonseminomatous germ cell tumor: a case report. ( 18472634 )
2008
14
Primary malignant teratoma with a primitive neuroectodermal tumor component in thyroid gland: a case report. ( 17596674 )
2007
15
Malignant teratoma vs. carcinoma with teratomatous elements, rather than metaplastic carcinoma. ( 17097879 )
2007
16
Malignant teratoma 32 years after treatment of germ cell tumor confined to testis. ( 16566989 )
2006
17
Malignant teratoma of the thyroid: case report. ( 17199442 )
2006
18
Case report: malignant teratoma of the sinonasal tract. ( 15368065 )
2005
19
Gamma mode of infiltration associated with poor prognosis in malignant teratoma of the ovary: A case report. ( 15922442 )
2005
20
Thyroid carcinoma arising from a sacrococcygeal mass: a malignant teratoma? ( 15307946 )
2004
21
Malignant teratoma of the orbit: a clinicopathological study of a case. ( 14685907 )
2003
22
Malignant teratoma of the thyroid: aggressive chemoradiation therapy is required after surgery. ( 12804109 )
2003
23
Malignant teratoma of the thyroid with primitive neuroepithelial and mesenchymal sarcomatous components. ( 11598856 )
2001
24
Malignant teratoma of the medulla oblongata in an adult male. ( 11810399 )
2001
25
Malignant teratoma of the thyroid with predominantly neuroepithelial differentiation. Fine needle aspiration cytologic, histologic and immunocytochemical features of a case. ( 10833994 )
2000
26
Malignant teratoma of the thyroid: review of literature and report of a case. ( 10758996 )
2000
27
Theriogenology question of the month. Malignant teratoma of the ovary. ( 10101408 )
1999
28
Malignant teratoma of the lung. ( 10665772 )
1999
29
Primary cervical malignant teratoma with a rib metastasis in an adult: five-year survival after surgery and chemotherapy. A case report with a review of the literature. ( 9818077 )
1998
30
Primary malignant teratoma of the thyroid gland: report and discussion of two cases. ( 9744468 )
1998
31
Immature malignant teratoma of the thyroid gland. ( 9646244 )
1998
32
Malignant teratoma of the testis presenting with bilateral inguinal lymphadenopathy and diagnosed by fine needle aspiration (FNA). ( 9134338 )
1997
33
Retroperitoneal surgery: its wider role in the management of malignant teratoma. ( 8777620 )
1996
34
Case report: malignant teratoma in the thyroid gland. ( 8983598 )
1996
35
Primary pulmonary malignant teratoma with yolk sac element associated with hematologic neoplasia. ( 8833994 )
1996
36
Retroperitoneal malignant teratoma. A case report. ( 8935151 )
1995
37
Malignant teratoma of the testicle: diagnosis suggested by preoperative ultrasonography. ( 7502125 )
1995
38
Malignant teratoma undifferentiated (MTU) metastasising solely as differentiated teratoma: implications for the aetiology of residual differentiated disease following successful chemotherapy. ( 8562181 )
1995
39
Ifosfamide and carboplatin combined with 41.8 degrees C whole-body hyperthermia in patients with refractory sarcoma and malignant teratoma. ( 7923163 )
1994
40
Carcinoma in situ of the testis followed by an overt malignant teratoma of the testis within 12 months. ( 7980264 )
1994
41
Mediastinal malignant teratoma and acute myeloid leukemia in a patient with Klinefelter's syndrome--comparison of DNA content in the two malignancies. ( 7946452 )
1994
42
MRI detection of ruptured malignant teratoma in the third ventricle. ( 8492886 )
1993
43
Prenatal diagnosis of intracranial teratoma. Prolonged survival after resection of a malignant teratoma diagnosed prenatally by ultrasound: a case report and literature review. ( 8382936 )
1993
44
Malignant teratoma of the lung with lymph node metastasis of the ectodermal compartment: a case report. ( 8318068 )
1993
45
Resection of an intracardiac metastasis from malignant teratoma of the testis. ( 8267441 )
1993
46
Malignant teratoma arising in a dysgenetic gonad. ( 7690731 )
1993
47
Management of malignant teratoma: does referral to a specialist unit matter? ( 8096954 )
1993
48
Suprasellar malignant teratoma with 11-year survival--case report. ( 1383861 )
1992
49
Pilot study to evaluate impact of a policy of adjuvant chemotherapy for high risk stage 1 malignant teratoma on overall relapse rate of stage 1 cancer patients. ( 1279211 )
1992
50
Malignant teratoma of the thyroid: case report and literature review of thyroid teratoma in adults. ( 1634206 )
1992

Variations for Malignant Teratoma

Expression for Malignant Teratoma

Search GEO for disease gene expression data for Malignant Teratoma.

Pathways for Malignant Teratoma

GO Terms for Malignant Teratoma

Cellular components related to Malignant Teratoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 pore complex GO:0046930 8.62 BAX BCL2

Biological processes related to Malignant Teratoma according to GeneCards Suite gene sharing:

(show all 21)
id Name GO ID Score Top Affiliating Genes
1 ovarian follicle development GO:0001541 9.6 BAX BCL2
2 neuron apoptotic process GO:0051402 9.59 BAX BCL2
3 extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 9.58 BAX BCL2
4 response to gamma radiation GO:0010332 9.58 BAX BCL2
5 positive regulation of intrinsic apoptotic signaling pathway GO:2001244 9.57 BAX BCL2
6 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress GO:0070059 9.56 BAX BCL2
7 extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 9.55 BAX BCL2
8 regulation of mitochondrial membrane potential GO:0051881 9.54 BAX BCL2
9 homeostasis of number of cells within a tissue GO:0048873 9.52 BAX BCL2
10 thyroid gland development GO:0030878 9.51 NKX2-1 TG
11 apoptotic mitochondrial changes GO:0008637 9.49 BAX BCL2
12 release of cytochrome c from mitochondria GO:0001836 9.48 BAX BCL2
13 B cell homeostasis GO:0001782 9.46 BAX BCL2
14 negative regulation of apoptotic signaling pathway GO:2001234 9.43 BAX BCL2
15 endoplasmic reticulum calcium ion homeostasis GO:0032469 9.4 BAX BCL2
16 regulation of protein heterodimerization activity GO:0043497 9.37 BAX BCL2
17 cellular response to organic substance GO:0071310 9.33 BAX BCL2 SYP
18 regulation of protein homodimerization activity GO:0043496 9.32 BAX BCL2
19 leukocyte homeostasis GO:0001776 9.26 BAX BCL2
20 regulation of nitrogen utilization GO:0006808 8.96 BAX BCL2
21 positive regulation of developmental pigmentation GO:0048087 8.62 BAX BCL2

Molecular functions related to Malignant Teratoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 channel activity GO:0015267 8.96 BAX BCL2
2 BH3 domain binding GO:0051434 8.62 BAX BCL2

Sources for Malignant Teratoma

3 CDC
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10 dbSNP
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16 ExPASy
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28 GO
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33 ICD10
34 ICD10 via Orphanet
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43 MESH via Orphanet
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65 SNOMED-CT via HPO
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67 TGDB
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70 UMLS via Orphanet
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