Mannose-Binding Lectin Protein Deficiency malady
Genetic diseases, Rare diseases categories
Aliases & Descriptions for Mannose-Binding Lectin Protein Deficiency:
MalaCards categories: See all MalaCards categories (disease lists)
Global: Genetic diseases, Rare diseases
NIH Rare Diseases:45 Mannose-binding lectin protein (mbl) deficiency is a complement component deficiency that alters the function of the body's immune system. this condition usually causes frequent and sometimes severe infections in infants and young children. this deficiency can occur as a result of one or more variations in the mbl2 gene, which codes for the mbl protein. a lack of this protein can cause this condition, but is likely further influenced by other genetic and environmental factors. last updated: 4/9/2012
MalaCards based summary: Mannose-Binding Lectin Protein Deficiency, also known as mannose-binding protein deficiency, is related to cryptosporidiosis and influenza. An important gene associated with Mannose-Binding Lectin Protein Deficiency is MBL2 (Mannose-Binding Lectin (Protein C) 2, Soluble).
Genetics Home Reference:23 Mannose-binding lectin deficiency is a condition that affects the immune system. People with this condition have low levels of an immune system protein called mannose-binding lectin in their blood. These individuals are prone to recurrent infections, including infections of the upper respiratory tract and other body systems. People with this condition may also contract more serious infections such as pneumonia and meningitis. Depending on the type of infection, the symptoms caused by the infections vary in frequency and severity.
Drugs for Mannose-Binding Lectin Protein Deficiency (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):
Interventional clinical trials:
Search NIH Clinical Center for Mannose-Binding Lectin Protein Deficiency
Search GEO for disease gene expression data for Mannose-Binding Lectin Protein Deficiency.
28ICD10 via Orphanet
37MESH via Orphanet
50OMIM via Orphanet
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
66UMLS via Orphanet