MCID: MPT001
MIFTS: 14

Mapt-Related Disorders malady

Summaries for Mapt-Related Disorders

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19GeneReviews, 33MalaCards
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MalaCards: Mapt-Related Disorders, also known as mapt-related tauopathies, is related to prion disease and apraxia. An important gene associated with Mapt-Related Disorders is MAPT (microtubule-associated protein tau), and among its related pathways are Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. and Neuroscience. The compounds spec-t and vitamin b12 have been mentioned in the context of this disorder. Related mouse phenotype other.

GeneReviews summary for ftdp-17

Aliases & Classifications for Mapt-Related Disorders

Sources:
19GeneReviews, 20GeneTests
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Aliases & Descriptions:

mapt-related disorders 19 20
mapt-related tauopathies 19


Related Diseases for Mapt-Related Disorders

Sources:
17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Mapt-Related Disorders:



Diseases related to mapt-related disorders

Clinical Features for Mapt-Related Disorders

Drugs & Therapeutics for Mapt-Related Disorders

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Mapt-Related Disorders

Drug clinical trials:

Search ClinicalTrials for Mapt-Related Disorders

Search NIH Clinical Center for Mapt-Related Disorders

Search CenterWatch for Mapt-Related Disorders

Genetic Tests for Mapt-Related Disorders

Sources:
20GeneTests
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Genetic tests related to Mapt-Related Disorders:

id Genetic test Affiliating Genes
1 Mapt-related Disorders20 MAPT

Anatomical Context for Mapt-Related Disorders

Animal Models for Mapt-Related Disorders or affiliated genes

Sources:
37MGI, 28inGenious Targeting Laboratory
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MGI Mouse Phenotypes related to Mapt-Related Disorders:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053959.1MAPT, PSEN1

Publications for Mapt-Related Disorders

Sources:
51PubMed
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Articles related to Mapt-Related Disorders:

idTitleAuthorsYear
1
MAPT-Related Disorders (20301678)
1993

Genetic Variations for Mapt-Related Disorders

Expression for genes affiliated with Mapt-Related Disorders

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Mapt-Related Disorders

Search GEO for disease gene expression data for Mapt-Related Disorders.

Pathways for genes affiliated with Mapt-Related Disorders

Sources:
54Reactome, 30KEGG, 38NCBI BioSystems Database, 4Cell Signaling Technology, 52QIAGEN
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Pathways related to Mapt-Related Disorders according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Hide members
9.1MAPT, PSEN1
29.1MAPT, PSEN1
39.1MAPT, PSEN1

Compounds for genes affiliated with Mapt-Related Disorders

Sources:
45Novoseek, 24HMDB, 29IUPHAR, 11DrugBank
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Compounds related to Mapt-Related Disorders according to GeneCards/GeneDecks:

(show all 18)
idCompoundScoreTop Affiliating Genes
1spec-t459.5MAPT, PSEN1
2vitamin b12459.4MAPT, PSEN1
34-hydroxynonenal45 2410.4MAPT, PSEN1
4lactacystin459.4MAPT, PSEN1
5kainate45 2910.4PSEN1, MAPT
6carbachol45 29 1111.4MAPT, PSEN1
7choline45 11 2411.4MAPT, PSEN1
8folate459.4PSEN1, MAPT
9valine459.4MAPT, PSEN1
10glycerol45 11 2411.3PSEN1, MAPT
11methionine459.3MAPT, PSEN1
12nmda45 2910.3MAPT, PSEN1
13glycogen45 2410.2MAPT, PSEN1
14proline459.2PSEN1, MAPT
15glutamine459.1MAPT, PSEN1
16h2o2459.1MAPT, PSEN1
17aspartate459.0MAPT, PSEN1
18cycloheximide458.8MAPT, PSEN1

GO Terms for genes affiliated with Mapt-Related Disorders

Sources:
16Gene Ontology
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Cellular components related to Mapt-Related Disorders according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1axonGO:0304249.1MAPT, PSEN1
2growth coneGO:0304268.8MAPT, PSEN1

Biological processes related to Mapt-Related Disorders according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1neuron migrationGO:0017649.1MAPT, PSEN1

Products for genes affiliated with Mapt-Related Disorders

  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Mapt-Related Disorders

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet