MCID: MPT001
MIFTS: 16

Mapt-Related Disorders malady

Categories: Genetic diseases, Mental diseases

Aliases & Classifications for Mapt-Related Disorders

Aliases & Descriptions for Mapt-Related Disorders:

Name: Mapt-Related Disorders 23 24
Mapt-Related Tauopathies 23 24
Multiple System Tauopathy with Presenile Dementia 24

Characteristics:

GeneReviews:

23
Penetrance The p.leu315arg mutation has been identified in individuals with ftdp-17 as well as in their unaffected parents, suggesting non-penetrance for this mutation in some individuals [van herpen et al 2003]...

Classifications:



Summaries for Mapt-Related Disorders

MalaCards based summary : Mapt-Related Disorders, also known as mapt-related tauopathies, is related to dementia, frontotemporal and dementia. An important gene associated with Mapt-Related Disorders is MAPT (Microtubule Associated Protein Tau), and among its related pathways/superpathways are Notch signaling pathway (KEGG) and Neuroscience.

GeneReviews: NBK1505

Related Diseases for Mapt-Related Disorders

Graphical network of the top 20 diseases related to Mapt-Related Disorders:



Diseases related to Mapt-Related Disorders

Symptoms & Phenotypes for Mapt-Related Disorders

Drugs & Therapeutics for Mapt-Related Disorders

Search Clinical Trials , NIH Clinical Center for Mapt-Related Disorders

Genetic Tests for Mapt-Related Disorders

Genetic tests related to Mapt-Related Disorders:

id Genetic test Affiliating Genes
1 Mapt-Related Disorders 24 MAPT

Anatomical Context for Mapt-Related Disorders

Publications for Mapt-Related Disorders

Articles related to Mapt-Related Disorders:

id Title Authors Year
1
MAPT-Related Disorders ( 20301678 )
1993

Variations for Mapt-Related Disorders

Expression for Mapt-Related Disorders

Search GEO for disease gene expression data for Mapt-Related Disorders.

Pathways for Mapt-Related Disorders

Pathways related to Mapt-Related Disorders according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1
Show member pathways
11.69 MAPT PSEN1
2 11.47 MAPT PSEN1
3 10.28 MAPT PSEN1

GO Terms for Mapt-Related Disorders

Cellular components related to Mapt-Related Disorders according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 dendrite GO:0030425 9.26 MAPT PSEN1
2 neuronal cell body GO:0043025 9.16 MAPT PSEN1
3 axon GO:0030424 8.96 MAPT PSEN1
4 growth cone GO:0030426 8.62 MAPT PSEN1

Biological processes related to Mapt-Related Disorders according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 memory GO:0007613 8.62 MAPT PSEN1

Sources for Mapt-Related Disorders

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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