MCID: MPT001
MIFTS: 22

Mapt-Related Disorders malady

Genetic diseases (common) category
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Summaries for Mapt-Related Disorders

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Sources:
19GeneReviews, 33MalaCards
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MalaCards: Mapt-Related Disorders, also known as mapt-related tauopathies, is related to semantic dementia and alzheimer disease type 2. An important gene associated with Mapt-Related Disorders is MAPT (microtubule-associated protein tau), and among its related pathways are Neuroscience and Alzheimer's disease. The compounds spec-t and vitamin b12 have been mentioned in the context of this disorder. Related mouse phenotype other.

GeneReviews summary for ftdp-17

Aliases & Classifications for Mapt-Related Disorders

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Sources:
19GeneReviews, 20GeneTests
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Genetic diseases (common)


Aliases & Descriptions:

mapt-related disorders 19 20
mapt-related tauopathies 19


Related Diseases for Mapt-Related Disorders

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Sources:
17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Mapt-Related Disorders:



Diseases related to mapt-related disorders

Symptoms for Mapt-Related Disorders

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Drugs & Therapeutics for Mapt-Related Disorders

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Sources:
42NIH Clinical Center, 6ClinicalTrials
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Drug clinical trials:

Search ClinicalTrials for Mapt-Related Disorders

Search NIH Clinical Center for Mapt-Related Disorders

Genetic Tests for Mapt-Related Disorders

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Sources:
20GeneTests
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Genetic tests related to Mapt-Related Disorders:

id Genetic test Affiliating Genes
1 Mapt-Related Disorders20 MAPT

Anatomical Context for Mapt-Related Disorders

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Animal Models for Mapt-Related Disorders or affiliated genes

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Sources:
37MGI
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MGI Mouse Phenotypes related to Mapt-Related Disorders:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053959.1MAPT, PSEN1

Publications for Mapt-Related Disorders

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Sources:
52PubMed
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Articles related to Mapt-Related Disorders:

idTitleAuthorsYear
1
MAPT-Related Disorders (20301678)
1993

Variations for Mapt-Related Disorders

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Expression for genes affiliated with Mapt-Related Disorders

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Sources:
2BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Mapt-Related Disorders

Search GEO for disease gene expression data for Mapt-Related Disorders.

Pathways for genes affiliated with Mapt-Related Disorders

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Sources:
50PathCards, 5Cell Signaling Technology, 30KEGG, 38NCBI BioSystems Database, 53QIAGEN
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Pathways related to Mapt-Related Disorders according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.1MAPT, PSEN1
2
Show member pathways
Alzheimers Disease38
9.1MAPT, PSEN1
39.1MAPT, PSEN1

Compounds for genes affiliated with Mapt-Related Disorders

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Sources:
45Novoseek, 24HMDB, 29IUPHAR, 11DrugBank
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Compounds related to Mapt-Related Disorders according to GeneCards/GeneDecks:

(show all 23)
idCompoundScoreTop Affiliating Genes
1spec-t459.5MAPT, PSEN1
2vitamin b12459.5MAPT, PSEN1
34-hydroxynonenal45 2410.5PSEN1, MAPT
4lactacystin459.5MAPT, PSEN1
5kainate45 2910.5MAPT, PSEN1
6carbachol45 29 1111.5PSEN1, MAPT
7choline45 24 1111.4MAPT, PSEN1
8folate459.4MAPT, PSEN1
9valine459.4PSEN1, MAPT
10glycerol45 24 1111.4MAPT, PSEN1
11methionine459.4MAPT, PSEN1
12nmda45 2910.4PSEN1, MAPT
13glycogen45 2410.4MAPT, PSEN1
14proline459.4MAPT, PSEN1
15glutamine459.3PSEN1, MAPT
16aspartate459.3MAPT, PSEN1
17cycloheximide459.3MAPT, PSEN1
18h2o2459.2PSEN1, MAPT
19arginine459.2MAPT, PSEN1
20threonine459.1MAPT, PSEN1
21retinoic acid45 2410.1MAPT, PSEN1
22glutamate459.0PSEN1, MAPT
23alanine458.8MAPT, PSEN1

GO Terms for genes affiliated with Mapt-Related Disorders

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Sources:
16Gene Ontology
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Cellular components related to Mapt-Related Disorders according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1axonGO:0304249.1MAPT, PSEN1
2growth coneGO:0304268.8MAPT, PSEN1

Biological processes related to Mapt-Related Disorders according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1neuron migrationGO:0017649.1MAPT, PSEN1

Products for genes affiliated with Mapt-Related Disorders

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Mapt-Related Disorders

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4CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
59SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet