MCID: MPT001
MIFTS: 22

Mapt-Related Disorders malady

Genetic diseases (common) category
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Summaries for Mapt-Related Disorders

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MalaCards based summary: Mapt-Related Disorders, also known as mapt-related tauopathies, is related to semantic dementia and alzheimer disease type 2. An important gene associated with Mapt-Related Disorders is MAPT (microtubule-associated protein tau), and among its related pathways are Neuroscience and Alzheimer's disease. The compounds spec-t and vitamin b12 have been mentioned in the context of this disorder. Related mouse phenotype other.

GeneReviews summary for ftdp-17

Aliases & Classifications for Mapt-Related Disorders

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Mapt-Related Disorders, Aliases & Descriptions:

Name: Mapt-Related Disorders 19 20
 
Mapt-Related Tauopathies 19


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Genetic diseases (common)


Related Diseases for Mapt-Related Disorders

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Graphical network of the top 20 diseases related to Mapt-Related Disorders:



Diseases related to mapt-related disorders

Symptoms for Mapt-Related Disorders

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Drugs & Therapeutics for Mapt-Related Disorders

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Drug clinical trials:

Search ClinicalTrials for Mapt-Related Disorders

Search NIH Clinical Center for Mapt-Related Disorders

Genetic Tests for Mapt-Related Disorders

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Genetic tests related to Mapt-Related Disorders:

id Genetic test Affiliating Genes
1 Mapt-Related Disorders20 MAPT

Anatomical Context for Mapt-Related Disorders

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Animal Models for Mapt-Related Disorders or affiliated genes

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MGI Mouse Phenotypes related to Mapt-Related Disorders:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053959.1MAPT, PSEN1

Publications for Mapt-Related Disorders

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Articles related to Mapt-Related Disorders:

idTitleAuthorsYear
1
MAPT-Related Disorders (20301678)
1993

Variations for Mapt-Related Disorders

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Expression for genes affiliated with Mapt-Related Disorders

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Expression patterns in normal tissues for genes affiliated with Mapt-Related Disorders

Search GEO for disease gene expression data for Mapt-Related Disorders.

Pathways for genes affiliated with Mapt-Related Disorders

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Pathways related to Mapt-Related Disorders according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.1MAPT, PSEN1
2
Show member pathways
Alzheimers Disease37
9.1MAPT, PSEN1
39.1MAPT, PSEN1

Compounds for genes affiliated with Mapt-Related Disorders

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Sources:
44Novoseek, 24HMDB, 28IUPHAR, 11DrugBank
See all sources

Compounds related to Mapt-Related Disorders according to GeneCards/GeneDecks:

(show all 23)
idCompoundScoreTop Affiliating Genes
1spec-t449.5MAPT, PSEN1
2vitamin b12449.5MAPT, PSEN1
34-hydroxynonenal44 2410.5PSEN1, MAPT
4lactacystin449.5MAPT, PSEN1
5kainate44 2810.5MAPT, PSEN1
6carbachol44 28 1111.5PSEN1, MAPT
7choline44 24 1111.4MAPT, PSEN1
8folate449.4MAPT, PSEN1
9valine449.4PSEN1, MAPT
10glycerol44 24 1111.4MAPT, PSEN1
11methionine449.4MAPT, PSEN1
12nmda44 2810.4PSEN1, MAPT
13glycogen44 2410.4MAPT, PSEN1
14proline449.4MAPT, PSEN1
15glutamine449.3PSEN1, MAPT
16aspartate449.3MAPT, PSEN1
17cycloheximide449.3MAPT, PSEN1
18h2o2449.2PSEN1, MAPT
19arginine449.2MAPT, PSEN1
20threonine449.1MAPT, PSEN1
21retinoic acid44 2410.1MAPT, PSEN1
22glutamate449.0PSEN1, MAPT
23alanine448.8MAPT, PSEN1

GO Terms for genes affiliated with Mapt-Related Disorders

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Cellular components related to Mapt-Related Disorders according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1axonGO:0304249.1MAPT, PSEN1
2growth coneGO:0304268.8MAPT, PSEN1

Biological processes related to Mapt-Related Disorders according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1neuron migrationGO:0017649.1MAPT, PSEN1

Products for genes affiliated with Mapt-Related Disorders

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  • Antibodies
  • Proteins
  • Lysates

Sources for Mapt-Related Disorders

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet