MCID: MPT001
MIFTS: 22

Mapt-Related Disorders malady

Genetic diseases (common) category

Summaries for Mapt-Related Disorders

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Sources:
20GeneReviews, 34MalaCards
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MalaCards: Mapt-Related Disorders, also known as mapt-related tauopathies, is related to semantic dementia and alzheimer disease type 2. An important gene associated with Mapt-Related Disorders is MAPT (microtubule-associated protein tau), and among its related pathways are Neuroscience and Alzheimer's disease. The compounds spec-t and vitamin b12 have been mentioned in the context of this disorder. Related mouse phenotype other.

GeneReviews summary for ftdp-17

Aliases & Classifications for Mapt-Related Disorders

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Sources:
20GeneReviews, 21GeneTests
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Genetic diseases (common)


Aliases & Descriptions:

mapt-related disorders 20 21
mapt-related tauopathies 20


Related Diseases for Mapt-Related Disorders

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Sources:
18GeneCards, 19GeneDecks
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Graphical network of the top 20 diseases related to Mapt-Related Disorders:



Diseases related to mapt-related disorders

Symptoms for Mapt-Related Disorders

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Drugs & Therapeutics for Mapt-Related Disorders

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Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials
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Approved drugs:

Search CenterWatch for Mapt-Related Disorders

Drug clinical trials:

Search ClinicalTrials for Mapt-Related Disorders

Search NIH Clinical Center for Mapt-Related Disorders

Search CenterWatch for Mapt-Related Disorders

Genetic Tests for Mapt-Related Disorders

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Sources:
21GeneTests
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Genetic tests related to Mapt-Related Disorders:

id Genetic test Affiliating Genes
1 Mapt-Related Disorders21 MAPT

Anatomical Context for Mapt-Related Disorders

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Animal Models for Mapt-Related Disorders or affiliated genes

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Sources:
38MGI
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MGI Mouse Phenotypes related to Mapt-Related Disorders:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053959.1MAPT, PSEN1

Publications for Mapt-Related Disorders

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Sources:
53PubMed
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Articles related to Mapt-Related Disorders:

idTitleAuthorsYear
1
MAPT-Related Disorders (20301678)
1993

Variations for Mapt-Related Disorders

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Expression for genes affiliated with Mapt-Related Disorders

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Sources:
2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Mapt-Related Disorders

Search GEO for disease gene expression data for Mapt-Related Disorders.

Pathways for genes affiliated with Mapt-Related Disorders

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Sources:
51PathCards, 5Cell Signaling Technology, 31KEGG, 39NCBI BioSystems Database, 54QIAGEN
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Pathways related to Mapt-Related Disorders according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.1MAPT, PSEN1
2
Show member pathways
Alzheimers Disease39
9.1MAPT, PSEN1
39.1MAPT, PSEN1

Compounds for genes affiliated with Mapt-Related Disorders

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Sources:
46Novoseek, 25HMDB, 30IUPHAR, 12DrugBank
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Compounds related to Mapt-Related Disorders according to GeneCards/GeneDecks:

(show all 23)
idCompoundScoreTop Affiliating Genes
1spec-t469.5MAPT, PSEN1
2vitamin b12469.5MAPT, PSEN1
34-hydroxynonenal46 2510.5PSEN1, MAPT
4lactacystin469.5MAPT, PSEN1
5kainate46 3010.5MAPT, PSEN1
6carbachol46 30 1211.5PSEN1, MAPT
7choline46 25 1211.4MAPT, PSEN1
8folate469.4MAPT, PSEN1
9valine469.4PSEN1, MAPT
10glycerol46 25 1211.4MAPT, PSEN1
11methionine469.4MAPT, PSEN1
12nmda46 3010.4PSEN1, MAPT
13glycogen46 2510.4MAPT, PSEN1
14proline469.4MAPT, PSEN1
15glutamine469.3PSEN1, MAPT
16aspartate469.3MAPT, PSEN1
17cycloheximide469.3MAPT, PSEN1
18h2o2469.2PSEN1, MAPT
19arginine469.2MAPT, PSEN1
20threonine469.1MAPT, PSEN1
21retinoic acid46 2510.1MAPT, PSEN1
22glutamate469.0PSEN1, MAPT
23alanine468.8MAPT, PSEN1

GO Terms for genes affiliated with Mapt-Related Disorders

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Sources:
17Gene Ontology
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Cellular components related to Mapt-Related Disorders according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1axonGO:0304249.1MAPT, PSEN1
2growth coneGO:0304268.8MAPT, PSEN1

Biological processes related to Mapt-Related Disorders according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1neuron migrationGO:0017649.1MAPT, PSEN1

Products for genes affiliated with Mapt-Related Disorders

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Mapt-Related Disorders

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet