MCID: MST001
MIFTS: 41

Mast-Cell Sarcoma malady

Blood diseases, Cancer diseases, Rare diseases categories

Aliases & Classifications for Mast-Cell Sarcoma

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Sources:
10Disease Ontology, 12DISEASES, 65UMLS, 36MeSH, 51Orphanet, 59SNOMED-CT, 42NCIt, 29ICD9CM, 66UMLS via Orphanet, 28ICD10 via Orphanet, 37MESH via Orphanet
See all sources

Aliases & Descriptions for Mast-Cell Sarcoma:

Name: Mast-Cell Sarcoma 10 12 65 36
 
Mast Cell Sarcoma 51


Classifications:



Characteristics (Orphanet epidemiological data):

51
mast cell sarcoma:
Age of onset: All ages


External Ids:

Disease Ontology10 DOID:355
NCIt42 C9348
ICD9CM29 202.6
MeSH36 D012515
Orphanet51 66661
UMLS via Orphanet66 C0036221
ICD10 via Orphanet28 C96.2
MESH via Orphanet37 D012515

Summaries for Mast-Cell Sarcoma

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Wikipedia:68 Mast cell sarcoma is an extremely aggressive form of sarcoma made up of neoplastic mast cells. A sarcoma... more...

MalaCards based summary: Mast-Cell Sarcoma, also known as mast cell sarcoma, is related to sarcoma and mastocytosis, and has symptoms including sarcoma, mastocytosis and splenomegaly. An important gene associated with Mast-Cell Sarcoma is KIT (V-Kit Hardy-Zuckerman 4 Feline Sarcoma Viral Oncogene Homolog), and among its related pathways are Regulation of KIT signaling and LDL Oxidation in Atherogenesis. Affiliated tissues include skin, bone and bone marrow, and related mouse phenotypes are skeleton and reproductive system.

Related Diseases for Mast-Cell Sarcoma

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Diseases related to Mast-Cell Sarcoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 92)
idRelated DiseaseScoreTop Affiliating Genes
1sarcoma10.8
2mastocytosis10.4
3acute lymphoblastic leukemia congenital sporadic aniridia10.3ANPEP, MPO
4benign epilepsy with centrotemporal spikes10.3CD2, KIT
5nodal marginal zone b-cell lymphoma10.3CSF2RA, MPO
6malignant teratocarcinosarcoma10.3KIT, VIM
7breast myofibroblastoma10.3KIT, VIM
8hepatosplenic t-cell lymphoma10.3PTPRC, VIM
9cutaneous solitary mastocytoma10.3KIT, PTPRC
10extraneural perineurioma10.3KIT, PDGFRA
11severe canavan disease10.3FIP1L1, PDGFRA
12dyskinesia of esophagus10.3PTPRC, VIM
13retroperitoneal liposarcoma10.2PTPRC, VIM
14oculomotor nerve paralysis10.2CD68, KIT
15vulvar nodular hidradenoma10.2KITLG, VIM
16alcoholic gastritis10.2KIT, MPO, PTPRC
17wheat allergic reaction10.2CMA1, KIT, KITLG
18bladder colonic type adenocarcinoma10.2PTPRC, VIM
19pineal dysgerminoma10.2CD68, MPO
20mastitis10.2CMA1, KIT, KITLG
21q fever10.2CD68, KIT
22angiodysplasia10.2KIT, VIM
23cecal benign neoplasm10.2KIT, PDGFRA, VIM
24hypereosinophilic syndrome, idiopathic, resistant to imatinib10.2FIP1L1, KIT, PDGFRA
25transient global amnesia10.2CD2, HEXA
26vascular myelopathy10.2FIP1L1, PDGFRA
27osteogenesis imperfecta - retinopathy - seizures - intellectual disability10.2FIP1L1, KIT, PDGFRA
28partial sensory epilepsy10.2KIT, KITLG, PDGFRA
29neuritis10.2KIT, PDGFRA, VIM
30hypergonadotropic ovarian failure, familial or sporadic10.2FIP1L1, KIT, PDGFRA
31hypothyroidism due to deficient transcription factors involved in pituitary development or function10.2KIT, VIM
32malignant pineal area germ cell neoplasm10.2KIT, PDGFRA, VIM
33total anomalous pulmonary venous return10.2KIT, KITLG, PDGFRA
34neuroma10.2KIT, KITLG, PDGFRA
35leukodystrophy10.2FIP1L1, KIT, PDGFRA
36leishmaniasis10.2KIT, PDGFRA, VIM
37mast cell disease10.2IFNA2, KIT, MPO
38prostate leiomyosarcoma10.2KIT, PDGFRA
39uterine corpus adenocarcinofibroma10.2CD68, KIT, VIM
40urinary bladder small cell neuroendocrine carcinoma10.2KIT, PDGFRA, PTPRC
41allergic conjunctivitis10.2ANPEP, CD68, MPO
42space motion sickness10.2IFNA2, KIT, KITLG
43leg dermatosis10.1IFNA2, KIT
44eosinophilic meningitis10.1CD68, PTPRC
45sm-ahnmd10.1CD68, PTPRC
46bladder urachal adenocarcinoma10.1KIT, VIM
47leukemia10.1
48systemic mastocytosis10.1
49sertoli cell tumor10.1
50lymphosarcoma10.1

Graphical network of the top 20 diseases related to Mast-Cell Sarcoma:



Diseases related to mast-cell sarcoma

Symptoms for Mast-Cell Sarcoma

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Symptoms:

 51 (show all 10)
  • sarcoma
  • mastocytosis
  • hepatomegaly/liver enlargement (excluding storage disease)
  • splenomegaly
  • mediastinal/hilar adenopathies
  • lymphadenopathy/polyadenopathies
  • bone marrow/medullar infiltration
  • weight loss/loss of appetite/break in weight curve/general health alteration
  • asthenia/fatigue/weakness
  • early death/lethality

HPO human phenotypes related to Mast-Cell Sarcoma:

(show all 6)
id Description Frequency HPO Source Accession
1 sarcoma hallmark (90%) HP:0100242
2 mastocytosis hallmark (90%) HP:0100495
3 splenomegaly typical (50%) HP:0001744
4 weight loss typical (50%) HP:0001824
5 hepatomegaly typical (50%) HP:0002240
6 mediastinal lymphadenopathy typical (50%) HP:0100721

Drugs & Therapeutics for Mast-Cell Sarcoma

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Drugs for Mast-Cell Sarcoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 7)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
CyproheptadineapprovedPhase 315129-03-32913
Synonyms:
1-Methyl-4-(5-dibenzo(a,e)cycloheptatrienylidene)piperidine
1-Methyl-4-(5H-dibenzo(a,d)cycloheptenylidene)piperidine
1-methyl-4-(5-dibenzo(a,e)cycloheptatrienylidene)piperidine
129-03-3
4-(5-Dibenzo(a,D)cyclohepten-5-ylidine)-1-methylpiperidine
4-(5-Dibenzo(a,d)cyclohepten-5-ylidine)-1-methylpiperidine
4-(5H-Dibenzo(a,D)cyclohepten-5-ylidene)-1-methylpiperidine
4-(5H-Dibenzo(a,d)cyclohepten-5-ylidene)-1-methylpiperidene
4-(5H-Dibenzo(a,d)cyclohepten-5-ylidene)-1-methylpiperidine
4-(5H-Dibenzo[a,d]cyclohepten-5-ylidene)-1-methylpiperidine
4-(5H-dibenzo[a,d][7]annulen-5-ylidene)-1-methylpiperidine
4-Dibenzo[a,D]cyclohepten-5-ylidene-1-methyl-piperidine
41354-29-4
5-(1-Methylpiperidylidene-4)-5H-dibenzo(a,d)cyclopheptene
5-(1-methylpiperidylidene-4)-5H-dibenzo(a,d)cyclopheptene
5-20-08-00500 (Beilstein Handbook Reference)
AC1L1ER8
AKOS004119847
Axoprol
BIDD:GT0324
BPBio1_000096
BPBio1_000155
BRD-K28143534-001-01-4
BRD-K28143534-003-03-6
BRN 1685976
BSPBio_000086
Biomol-NT_000131
C06935
CAS-969-33-5
CCRIS 5232
CHEBI:4046
CHEMBL516
CID2913
CYPROHEPTADINE
Ciproheptadina
Ciproheptadina [INN-Spanish]
Ciprovit
Ciprovit (TN)
Cypoheptadine
Cyproheptadiene
Cyproheptadin
Cyproheptadine
Cyproheptadine (INN)
 
Cyproheptadine Hcl
Cyproheptadine Hydrochloride
Cyproheptadine [INN:BAN]
Cyproheptadinum
Cyproheptadinum [INN-Latin]
D07765
DB00434
Dibenzosuberonone/Cyproheptadine
Dihexazin
Dronactin
EINECS 204-928-9
Eiproheptadine
Glutodina
HMS2090P20
HSDB 3048
L001016
LS-114933
Lopac-C-6022
Lopac0_000246
MK 141
MolPort-002-507-777
NCGC00015252-01
NCGC00015252-02
NCGC00015252-03
NCGC00015252-09
NCGC00024293-02
NCGC00024293-04
NCGC00024293-05
Oprea1_498140
PDSP1_001229
PDSP2_001213
Periactin
Periactine
Periactinol
Prestwick0_000103
Prestwick1_000103
Prestwick2_000103
Prestwick3_000103
SPBio_002025
STK802098
Tocris-0996
UNII-2YHB6175DO
Viternum
nchembio.559-comp10
2
Histamine PhosphateapprovedPhase 385251-74-165513
Synonyms:
1H-Imidazole-4-ethanamine, phosphate (1:2)
2-Imidazol-4-ylethylamine orthophosphoric acid (1:2)
4-(2-Aminoethyl)imidazole bis(dihydrogen phosphate)
4-(2-Aminoethyl)imidazole di-acid phosphate
4-2(2-Aminoethyl)Imidazole-Di-Acid Phosphate
51-74-1
53623-99-7
74-56-6
AC1L23E4
CID65513
D04445
DB00667
EINECS 200-118-4
 
H0147
Histamine Positive Skin Test Control
Histamine Positive skin test control
Histamine acid phosphate
Histamine biphosphate
Histamine dihydrogen phosphate
Histamine diphosphate
Histamine phosphate (1:2)
Histamine phosphate (TN)
Histamine phosphate (USP)
Histamine phosphate [USP]
Histamine positive
Histaminum
LS-78569
UNII-QWB37T4WZZ
3
histaminePhase 385275614-87-8, 51-45-6774
Synonyms:
.beta.-Imidazolyl-4-ethylamine
1H-Imidazole-4-ethanamine
1H-Imidazole-5-ethanamine
1avn
1qft
2-(1H-Imidazol-4-yl)ethanamine
2-(1H-Imidazol-4-yl)ethylamine
2-(1H-Imidazol-5-yl)ethanamine
2-(1H-Imidazol-5-yl)ethylamine
2-(1H-imidazol-4-yl)ethan-1-amine
2-(1H-imidazol-5-yl)ethanamine
2-(3H-Imidazol-4-yl)-ethylamine
2-(4-Imidazolyl)ethanamine
2-(4-Imidazolyl)ethylamine
2-Imidazol-4-yl-Ethylamine
2-Imidazol-4-ylethylamine
2-[4-Imidazolyl]ethylamine
4-(2-Aminoethyl)-1H-imidazole
4-(2-Aminoethyl)imidazole
4-Imidazoleethylamine
5-Imidazoleethylamine
51-45-6
53290_FLUKA
64422-25-9
924364-91-0
AC-13185
AC1L19ZT
AC1Q54BV
AC1Q54BW
AKOS000274386
ALBB-005968
BCBcMAP01_000250
BSPBio_001117
BSPBio_002124
Bio1_000487
Bio1_000976
Bio1_001465
Bio2_000389
Bio2_000869
C00388
CCRIS 6535
CHEBI:18295
CHEMBL90
CID774
D08040
DivK1c_000308
EINECS 200-100-6
Eramin
Ergamine
Ergotidine
F411C768-A159-4FC0-A195-291A08BB03AA
Free histamine
H7125_SIGMA
HMS1362G19
HMS1792G19
HMS1990G19
HSDB 3338
HSM
Histamine
Histamine (DCF)
Histamine Base
Histamine [USAN]
Histamine, Free Base
Histaminum
 
Histaminum (TN)
IDI1_000308
IDI1_002144
Imidazole-4-ethylamine
Istamina
Istamina [Italian]
KBio1_000308
KBio2_000457
KBio2_001325
KBio2_003025
KBio2_003893
KBio2_005593
KBio2_006461
KBio3_000853
KBio3_000854
KBio3_001344
KBioGR_000457
KBioGR_001580
KBioSS_000457
KBioSS_001325
L-Histamin base
L-Histamine
L-histamine
L000292
LS-75835
Lopac-H-7250
Lopac0_000595
MLS000069447
MolPort-001-785-597
MolPort-002-042-264
NCGC00015513-01
NCGC00015513-08
NCGC00093371-02
NCGC00093371-03
NCGC00093371-04
NCGC00093371-05
NINDS_000308
NSC 33792
NSC33792
SDCCGMLS-0066601.P001
SMP1_000151
SMR000059091
SPBio_000729
ST073926
STK346752
STOCK5S-55669
Spectrum2_000665
Spectrum3_000452
Spectrum4_000960
Spectrum5_000796
Spectrum_000845
Theramine
UNII-820484N8I3
WLN: T5M CNJ D2Z
ZERO/004089
[3H]histamine
b-Imidazolyl-4-ethylamine
beta-Aminoethylglyoxaline
beta-Aminoethylimidazole
beta-Aminothethylglyoxaline
beta-Imidazolyl-4-ethylamine
beta-aminothethylglyoxaline
bmse000744
histamine
nchembio.87-comp54
nchembio714-comp1
4
SerotoninPhase 3285350-67-95202
Synonyms:
3-(2-Aminoethyl)-1H-indol-5-ol
3-(2-Aminoethyl)indol-5-ol
3-(b-Aminoethyl)-5-hydroxyindole
5-HT
5-HTA
5-Hydroxy-3-(b-aminoethyl)indole
 
5-Hydroxy-tryptamine
5-Hydroxyltryptamine
5-Hydroxytriptamine
5-Hydroxytryptamine
Antemovis
DS substance
Enteramin
Enteramine
5AntipruriticsPhase 3586
6
imatinibapprovedPhase 2567152459-95-5644241, 5291
Synonyms:
112GI019
152459-95-5
1iep
1xbb
4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE
4-(4-METHYL-piperazin-1-ylmethyl)-N-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide
4-[(4-Methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]-phenyl]benzamide
4-[(4-methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]-benzamide methanesulfonate
4-[(4-methylpiperazin-1-yl)methyl]-N-(4-methyl-3-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}phenyl)benzamide
4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide
4-[(4-methylpiperazin-1-yl)methyl]-N-{4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl}benzamide
AC-524
AC1L1K0Z
AKOS000280662
BIDD:GT0047
BRD-K92723993-066-02-9
Benzamide, 4-[(4-methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]- (9CI)
CCRIS 9076
CGP 57148B
CGP57148
CGP57148B
CHEBI:45783
CHEMBL941
CID5291
Cgp 57148
D08066
DB00619
DB03261
EN002706
FT-0083542
Glamox
Glamox (TN)
 
Gleevec
Glivec
HMS2089D03
I01-1232
Imatinib
Imatinib (INN)
Imatinib Mesylate
Imatinib Methansulfonate
Imatinib [INN:BAN]
Imatinib free base
Imatinibum
Kinome_3724
LS-182208
LS-187106
MolPort-000-883-342
N-(3-(4-(pyridin-3-yl)pyrimidin-2-ylamino)-4-methylphenyl)-4-((4-methylpiperazin-1-yl)methyl)benzamide
NCGC00159456-02
NCGC00159456-03
NCGC00159456-04
NSC743414
STI
STI 571
STI-571
STI571
STK617705
UNII-BKJ8M8G5HI
alpha-(4-Methyl-1-piperazinyl)-3'-((4-(3-pyridyl)-2-pyrimidinyl)amino)-P-toluidide
alpha-(4-Methyl-1-piperazinyl)-3'-((4-(3-pyridyl)-2-pyrimidinyl)amino)-p-tolu-p-toluidide
imatinib
nchembio.117-comp23
nchembio.162-comp5
nchembio.282-comp6
nchembio.83-comp14
sti-571
7ColaNutraceutical1690

Interventional clinical trials:

idNameStatusNCT IDPhase
1Cyproheptadine in Preventing Weight Loss in Children Receiving Chemotherapy for CancerTerminatedNCT01132547Phase 3
2Phase II Study of Imatinib Mesylate in Patients With Life Threatening Malignant Rare DiseasesCompletedNCT00154388Phase 2
3Study of BLU-285 in Patients With Advanced Systemic Mastocytosis (advSM) and Relapsed or Refractory Myeloid MalignanciesRecruitingNCT02561988Phase 1
4Study of Information Received About Fertility and Infertility in Patients Who Have Finished Treatment for CancerRecruitingNCT01295463
5Evaluation of Patient Satisfaction With and Acceptance of Their Totally-implanted Central Venous CatheterTerminatedNCT01616537
6Heparin or M-EDTA in Preventing Catheter-Related Infections and Blockages in Patients at High Risk for a Catheter-Related InfectionWithdrawnNCT00378781

Search NIH Clinical Center for Mast-Cell Sarcoma


Cochrane evidence based reviews: Mast-Cell Sarcoma

Genetic Tests for Mast-Cell Sarcoma

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Anatomical Context for Mast-Cell Sarcoma

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MalaCards organs/tissues related to Mast-Cell Sarcoma:

33
Skin, Bone, Bone marrow, Liver, Colon, Uterus

Animal Models for Mast-Cell Sarcoma or affiliated genes

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MGI Mouse Phenotypes related to Mast-Cell Sarcoma:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053907.8C5AR1, CD68, CXCR4, HEXA, KIT, KITLG
2MP:00053897.2ANPEP, C5AR1, CCR5, CXCR4, HEXA, KIT
3MP:00053875.3ANPEP, C5AR1, CCR5, CD68, CMA1, CXCR4
4MP:00053975.1ANPEP, C5AR1, CCR5, CD68, CMA1, CXCR4

Publications for Mast-Cell Sarcoma

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Articles related to Mast-Cell Sarcoma:

(show all 24)
idTitleAuthorsYear
1
Mast cell sarcoma: clinical management. (24745684)
2014
2
Pediatric mast cell sarcoma of temporal bone with novel L799F (2395 C>T) KIT mutation, mimicking histiocytic neoplasm. (23388130)
2013
3
Mast cell sarcoma mimicking metastatic colon carcinoma. (24141335)
2013
4
Mast cell sarcoma in an infant: a case report and review of the literature. (23211696)
2013
5
Mast cell sarcoma: a rare and potentially under-recognized diagnostic entity with specific therapeutic implications. (23196796)
2013
6
Mast cell sarcoma: a rare and aggressive entity--report of two cases and review of the literature. (23129735)
2013
7
Mast cell sarcoma with megakaryocytic differentiation in a calf. (22813945)
2012
8
Malignant transformation of mastocytoma developed on skin mastocytosis into cutaneous mast cell sarcoma. (22498828)
2012
9
Mast cell sarcoma of the scalp: the first sign of undisclosed systemic mastocytosis? (22963840)
2012
10
Successful treatment of mast cell sarcoma of the uterus with imatinib. (22020400)
2011
11
Mast-cell sarcoma of the tibia. (17405977)
2007
12
Characterization of novel stem cell factor responsive human mast cell lines LAD 1 and 2 established from a patient with mast cell sarcoma/leukemia; activation following aggregation of FcepsilonRI or FcgammaRI. (12801524)
2003
13
Morphologic and immunophenotypic properties of neoplastic cells in a case of mast cell sarcoma. (12826896)
2003
14
Temporary response of localized intracranial mast cell sarcoma to combination chemotherapy. (11216707)
2001
15
Mast cell sarcoma with tissue eosinophilia arising in the ascending colon. (10430280)
1999
16
Association of bone marrow mastocytosis with extremely immature extramedullary mast cell sarcoma]. (9273545)
1997
17
What is your diagnosis? Mast cell sarcoma. (9097238)
1997
18
Brief communication, Histopathology of a spontaneously developing mast cell sarcoma in a Wistar rat. (8736393)
1996
19
Use of hyperthermia and radiotherapy in treatment of a large mast cell sarcoma in a dog. (3145930)
1988
20
Mast cell sarcoma of the larynx. (3088063)
1986
21
Mast cell sarcoma of the larynx in a dog: a case report. (104092)
1979
22
Multiple genital neoplasia (mast cell sarcoma, seminoma, and sertoli cell tumor) in a dog. (13306668)
1956
23
Preliminary observations on the use of cortisone in canine mast cell sarcoma. (13108793)
1953
24
Neoplastic diseases of dogs; mast cell sarcoma, lymphosarcoma, histiocytoma. (18118928)
1948

Variations for Mast-Cell Sarcoma

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Expression for genes affiliated with Mast-Cell Sarcoma

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Search GEO for disease gene expression data for Mast-Cell Sarcoma.

Pathways for genes affiliated with Mast-Cell Sarcoma

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GO Terms for genes affiliated with Mast-Cell Sarcoma

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Cellular components related to Mast-Cell Sarcoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1azurophil granuleGO:004258210.6HEXA, MPO
2external side of plasma membraneGO:00098979.2ANPEP, CCR5, CD2, KIT, PTPRC
3cell surfaceGO:00099868.4C5AR1, CCR5, CD2, CXCR4, KIT, PTPRC
4integral component of plasma membraneGO:00058877.3ANPEP, C5AR1, CCR5, CD2, CSF2RA, PDGFRA
5plasma membraneGO:00058865.7C5AR1, CCR5, CD2, CD68, CSF2RA, CXCR4

Biological processes related to Mast-Cell Sarcoma according to GeneCards Suite gene sharing:

(show all 18)
idNameGO IDScoreTop Affiliating Genes
1ectopic germ cell programmed cell deathGO:003523410.6KIT, KITLG
2positive regulation of phospholipase C activityGO:001086310.6KIT, PDGFRA
3regulation of chemotaxisGO:005092010.1CXCR4, PDGFRA
4entry into host cellGO:003026010.1CCR5, CXCR4
5dendritic cell chemotaxisGO:000240710.1CCR5, CXCR4
6angiotensin maturationGO:000200310.1ANPEP, CMA1
7activation of MAPKK activityGO:00001869.7CSF2RA, KIT, KITLG, PDGFRA
8Ras protein signal transductionGO:00072659.7CSF2RA, KIT, KITLG, PDGFRA
9insulin receptor signaling pathwayGO:00082869.7CSF2RA, KIT, KITLG, PDGFRA
10fibroblast growth factor receptor signaling pathwayGO:00085439.6CSF2RA, KIT, KITLG, PDGFRA
11viral entry into host cellGO:00467189.5ANPEP, CCR5, CXCR4
12vascular endothelial growth factor receptor signaling pathwayGO:00480109.5CSF2RA, KIT, KITLG, PDGFRA
13MAPK cascadeGO:00001659.4CCR5, CSF2RA, KIT, KITLG, PDGFRA
14cell surface receptor signaling pathwayGO:00071669.3CCR5, CD2, CDA, IFNA2, PTPRC
15activation of MAPK activityGO:00001879.3C5AR1, CXCR4, KIT, PTPRC
16positive regulation of cytosolic calcium ion concentrationGO:00072049.2C5AR1, CCR5, CXCR4, PDGFRA
17axon guidanceGO:00074118.9CSF2RA, KIT, KITLG, PDGFRA, PTPRC
18inflammatory responseGO:00069548.1C5AR1, CCR5, CXCR4, IFNA2, KIT, TNFRSF8

Molecular functions related to Mast-Cell Sarcoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1virus receptor activityGO:00016189.0ANPEP, CCR5, CXCR4

Sources for Mast-Cell Sarcoma

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet