MCID: MST001
MIFTS: 46

Mast-Cell Sarcoma malady

Categories: Blood diseases, Rare diseases, Cancer diseases

Aliases & Classifications for Mast-Cell Sarcoma

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Sources:
11Disease Ontology, 13DISEASES, 29ICD10, 30ICD10 via Orphanet, 31ICD9CM, 38MeSH, 39MESH via Orphanet, 44NCIt, 53Orphanet, 61SNOMED-CT, 67UMLS, 68UMLS via Orphanet
See all MalaCards sources

Aliases & Descriptions for Mast-Cell Sarcoma:

Name: Mast-Cell Sarcoma 11 38 13 67
 
Mast Cell Sarcoma 53

Characteristics:

Orphanet epidemiological data:

53
mast cell sarcoma:
Age of onset: All ages

Classifications:



External Ids:

Disease Ontology11 DOID:355
ICD1029 C96.2
ICD9CM31 202.6
MeSH38 D012515
NCIt44 C9348
Orphanet53 ORPHA66661
ICD10 via Orphanet30 C96.2
MESH via Orphanet39 D012515
UMLS via Orphanet68 C0036221

Summaries for Mast-Cell Sarcoma

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Wikipedia:70 Mast cell sarcoma is an extremely aggressive form of sarcoma made up of neoplastic mast cells. A sarcoma... more...

MalaCards based summary: Mast-Cell Sarcoma, also known as mast cell sarcoma, is related to non-amyloid monoclonal immunoglobulin deposition disease and isthmian coarctation, and has symptoms including sarcoma, mastocytosis and splenomegaly. An important gene associated with Mast-Cell Sarcoma is KIT (KIT Proto-Oncogene Receptor Tyrosine Kinase), and among its related pathways are Regulation of KIT signaling and Dendritic Cells Developmental Lineage Pathway. Affiliated tissues include skin, myeloid and colon, and related mouse phenotypes are neoplasm and muscle.

Related Diseases for Mast-Cell Sarcoma

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Diseases related to Mast-Cell Sarcoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 66)
idRelated DiseaseScoreTop Affiliating Genes
1non-amyloid monoclonal immunoglobulin deposition disease10.6CSF2RA, MPO
2isthmian coarctation10.6ANPEP, FCGR1A
3relapsing epidemic typhus10.5KIT, PDGFRA
4acquired porencephaly10.5FIP1L1, PDGFRA
5chronic end-stage hepatitis c10.5KIT, VIM
6myopia10.5PTPRC, VIM
7olfactory nerve disease10.5KIT, PTPRC
8merkel cell carcinoma10.5FIP1L1, PDGFRA
9cascade stomach10.5CD2, FCGR1A
10idiopathic subglottic tracheal stenosis10.5PTPRC, VIM
11sarcoma10.4
12vagina leiomyosarcoma10.4KIT, PDGFRA
13tonsillar pillar cancer10.4KIT, MPO, PTPRC
14pericoronitis10.4CMA1, KIT, KITLG
15congenital disorder of glycosylation, type iq10.4FIP1L1, KIT, PDGFRA
16dens in dente and palatal invaginations10.4MPO, PTPRC, VIM
17cutaneous solitary mastocytoma10.4CMA1, KIT, KITLG
18multiple chemical sensitivity10.4CD2, KIT, PTPRC
19dentinogenesis imperfecta, shields type ii10.4KIT, KITLG, PDGFRA
20restrictive cardiomyopathy10.4KIT, KITLG, PDGFRA
21parametritis10.3CD2, FCGR1A
22prostate small cell carcinoma10.3KIT, PDGFRA, PTPRC
23ureter squamous cell carcinoma10.3KIT, PTPRC
24hypereosinophilic syndrome, idiopathic, resistant to imatinib10.3IFNA2, KIT, MPO
25movement disease10.3IFNA2, KIT, KITLG
26central cloudy dystrophy of francois10.3CMA1, FIP1L1, PDGFRA
27anus leiomyosarcoma10.3PDGFRA, PTPRC, VIM
28cell type cancer10.3KIT, PDGFRA, PTPRC
29corneal granular dystrophy10.3CMA1, FIP1L1, KIT, KITLG
30upper gum cancer10.3MPO, PTPRC
31malignant biphasic mesothelioma10.2IFNA2, KIT, PDGFRA
32loeffler syndrome10.2FIP1L1, KIT, KITLG, PDGFRA
33male reproductive system disease10.2CD2, FIP1L1, KIT, PDGFRA
34filamentary keratitis10.2CD2, KIT, KITLG, PDGFRA
35hypotrichosis simplex10.2FIP1L1, IFNA2, PDGFRA
36auricular cancer10.1TNFRSF8, VIM
37peritonitis10.1KIT, TNFRSF8
38nystagmus 3, congenital, autosomal dominant10.1ABL1, ANPEP, MPO
39mastocytosis10.0
40mastroiacovo de rosa satta syndrome10.0IFNA2, KIT, KITLG, PDGFRA
41thrombocythemia 310.0IFNA2, KIT, KITLG, PDGFRA
42t-b+ severe combined immunodeficiency due to cd3delta/cd3epsilon/cd3zeta10.0ABL1, FIP1L1, KIT, PDGFRA
43kala-azar 110.0KIT, KITLG, PDGFRA, PTPRC, VIM
44nutritional deficiency disease9.9KIT, PTPRC, TNFRSF8
45taylor's syndrome9.8CCR5, CXCR4, IFNA2
46gastrointestinal stromal tumor9.8ABL1, KIT, KITLG, PDGFRA, VIM
47diffuse cutaneous mastocytosis9.8CD2, CMA1, FIP1L1, KIT, KITLG, PDGFRA
48leukemia9.7
49systemic mastocytosis9.7
50sertoli cell tumor9.7

Graphical network of the top 20 diseases related to Mast-Cell Sarcoma:



Diseases related to mast-cell sarcoma

Symptoms for Mast-Cell Sarcoma

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Human phenotypes related to Mast-Cell Sarcoma:

 63 53 (show all 9)
id Description HPO Frequency Orphanet Frequency HPO Source Accession
1 sarcoma63 53 hallmark (90%) Very frequent (99-80%) HP:0100242
2 mastocytosis63 53 hallmark (90%) Very frequent (99-80%) HP:0100495
3 splenomegaly63 53 typical (50%) Frequent (79-30%) HP:0001744
4 weight loss63 53 typical (50%) Frequent (79-30%) HP:0001824
5 hepatomegaly63 53 typical (50%) Frequent (79-30%) HP:0002240
6 mediastinal lymphadenopathy63 53 typical (50%) Frequent (79-30%) HP:0100721
7 lymphadenopathy53 Frequent (79-30%)
8 fatigue53 Frequent (79-30%)
9 hypoplasia of the ear cartilage53 Frequent (79-30%)

Drugs & Therapeutics for Mast-Cell Sarcoma

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Drugs for Mast-Cell Sarcoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 16)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
CyproheptadineapprovedPhase 320129-03-32913
Synonyms:
1-Methyl-4-(5-dibenzo(a,e)cycloheptatrienylidene)piperidine
1-Methyl-4-(5H-dibenzo(a,d)cycloheptenylidene)piperidine
1-methyl-4-(5-dibenzo(a,e)cycloheptatrienylidene)piperidine
129-03-3
4-(5-Dibenzo(a,D)cyclohepten-5-ylidine)-1-methylpiperidine
4-(5-Dibenzo(a,d)cyclohepten-5-ylidine)-1-methylpiperidine
4-(5H-Dibenzo(a,D)cyclohepten-5-ylidene)-1-methylpiperidine
4-(5H-Dibenzo(a,d)cyclohepten-5-ylidene)-1-methylpiperidene
4-(5H-Dibenzo(a,d)cyclohepten-5-ylidene)-1-methylpiperidine
4-(5H-Dibenzo[a,d]cyclohepten-5-ylidene)-1-methylpiperidine
4-(5H-dibenzo[a,d][7]annulen-5-ylidene)-1-methylpiperidine
4-Dibenzo[a,D]cyclohepten-5-ylidene-1-methyl-piperidine
41354-29-4
5-(1-Methylpiperidylidene-4)-5H-dibenzo(a,d)cyclopheptene
5-(1-methylpiperidylidene-4)-5H-dibenzo(a,d)cyclopheptene
5-20-08-00500 (Beilstein Handbook Reference)
AC1L1ER8
AKOS004119847
Axoprol
BIDD:GT0324
BPBio1_000096
BPBio1_000155
BRD-K28143534-001-01-4
BRD-K28143534-003-03-6
BRN 1685976
BSPBio_000086
Biomol-NT_000131
C06935
CAS-969-33-5
CCRIS 5232
CHEBI:4046
CHEMBL516
CID2913
CYPROHEPTADINE
Ciproheptadina
Ciproheptadina [INN-Spanish]
Ciprovit
Ciprovit (TN)
Cypoheptadine
Cyproheptadiene
Cyproheptadin
Cyproheptadine
 
Cyproheptadine (INN)
Cyproheptadine Hcl
Cyproheptadine [INN:BAN]
Cyproheptadinum
Cyproheptadinum [INN-Latin]
D07765
DB00434
Dibenzosuberonone/Cyproheptadine
Dihexazin
Dronactin
EINECS 204-928-9
Eiproheptadine
Glutodina
HMS2090P20
HSDB 3048
L001016
LS-114933
Lopac-C-6022
Lopac0_000246
MK 141
MolPort-002-507-777
NCGC00015252-01
NCGC00015252-02
NCGC00015252-03
NCGC00015252-09
NCGC00024293-02
NCGC00024293-04
NCGC00024293-05
Oprea1_498140
PDSP1_001229
PDSP2_001213
Periactin
Periactine
Periactinol
Prestwick0_000103
Prestwick1_000103
Prestwick2_000103
Prestwick3_000103
SPBio_002025
STK802098
Tocris-0996
UNII-2YHB6175DO
Viternum
nchembio.559-comp10
2
HistamineapprovedPhase 3103475614-87-8, 51-45-6774
Synonyms:
.beta.-Imidazolyl-4-ethylamine
1H-Imidazole-4-ethanamine
1H-Imidazole-5-ethanamine
1avn
1qft
2-(1H-Imidazol-4-yl)ethanamine
2-(1H-Imidazol-4-yl)ethylamine
2-(1H-Imidazol-5-yl)ethanamine
2-(1H-Imidazol-5-yl)ethylamine
2-(1H-imidazol-4-yl)ethan-1-amine
2-(1H-imidazol-5-yl)ethanamine
2-(3H-Imidazol-4-yl)-ethylamine
2-(4-Imidazolyl)ethanamine
2-(4-Imidazolyl)ethylamine
2-Imidazol-4-yl-Ethylamine
2-Imidazol-4-ylethylamine
2-[4-Imidazolyl]ethylamine
4-(2-Aminoethyl)-1H-imidazole
4-(2-Aminoethyl)imidazole
4-Imidazoleethylamine
5-Imidazoleethylamine
51-45-6
53290_FLUKA
64422-25-9
924364-91-0
AC-13185
AC1L19ZT
AC1Q54BV
AC1Q54BW
AKOS000274386
ALBB-005968
BCBcMAP01_000250
BSPBio_001117
BSPBio_002124
Bio1_000487
Bio1_000976
Bio1_001465
Bio2_000389
Bio2_000869
C00388
CCRIS 6535
CHEBI:18295
CHEMBL90
CID774
D08040
DivK1c_000308
EINECS 200-100-6
Eramin
Ergamine
Ergotidine
F411C768-A159-4FC0-A195-291A08BB03AA
Free histamine
H7125_SIGMA
HMS1362G19
HMS1792G19
HMS1990G19
HSDB 3338
HSM
Histamine
Histamine (DCF)
Histamine Base
Histamine [USAN]
Histamine, Free Base
Histaminum
 
Histaminum (TN)
IDI1_000308
IDI1_002144
Imidazole-4-ethylamine
Istamina
Istamina [Italian]
KBio1_000308
KBio2_000457
KBio2_001325
KBio2_003025
KBio2_003893
KBio2_005593
KBio2_006461
KBio3_000853
KBio3_000854
KBio3_001344
KBioGR_000457
KBioGR_001580
KBioSS_000457
KBioSS_001325
L-Histamin base
L-Histamine
L-histamine
L000292
LS-75835
Lopac-H-7250
Lopac0_000595
MLS000069447
MolPort-001-785-597
MolPort-002-042-264
NCGC00015513-01
NCGC00015513-08
NCGC00093371-02
NCGC00093371-03
NCGC00093371-04
NCGC00093371-05
NINDS_000308
NSC 33792
NSC33792
SDCCGMLS-0066601.P001
SMP1_000151
SMR000059091
SPBio_000729
ST073926
STK346752
STOCK5S-55669
Spectrum2_000665
Spectrum3_000452
Spectrum4_000960
Spectrum5_000796
Spectrum_000845
Theramine
UNII-820484N8I3
WLN: T5M CNJ D2Z
ZERO/004089
[3H]histamine
b-Imidazolyl-4-ethylamine
beta-Aminoethylglyoxaline
beta-Aminoethylimidazole
beta-Aminothethylglyoxaline
beta-Imidazolyl-4-ethylamine
beta-aminothethylglyoxaline
bmse000744
histamine
nchembio.87-comp54
nchembio714-comp1
3
Histamine PhosphateapprovedPhase 3103351-74-165513
Synonyms:
1H-Imidazole-4-ethanamine, phosphate (1:2)
2-Imidazol-4-ylethylamine orthophosphoric acid (1:2)
4-(2-Aminoethyl)imidazole bis(dihydrogen phosphate)
4-(2-Aminoethyl)imidazole di-acid phosphate
4-2(2-Aminoethyl)Imidazole-Di-Acid Phosphate
51-74-1
53623-99-7
74-56-6
AC1L23E4
CID65513
D04445
DB00667
 
EINECS 200-118-4
H0147
Histamine acid phosphate
Histamine biphosphate
Histamine dihydrogen phosphate
Histamine diphosphate
Histamine phosphate (1:2)
Histamine phosphate (TN)
Histamine phosphate (USP)
Histamine phosphate [USP]
Histamine positive
Histaminum
LS-78569
UNII-QWB37T4WZZ
4Neurotransmitter AgentsPhase 317734
5Serotonin AgentsPhase 33102
6Serotonin AntagonistsPhase 31381
7
SerotoninPhase 3356650-67-95202
Synonyms:
3-(2-Aminoethyl)-1H-indol-5-ol
3-(2-Aminoethyl)indol-5-ol
3-(b-Aminoethyl)-5-hydroxyindole
5-HT
5-HTA
5-Hydroxy-3-(b-aminoethyl)indole
 
5-Hydroxy-tryptamine
5-Hydroxyltryptamine
5-Hydroxytriptamine
5-Hydroxytryptamine
Antemovis
DS substance
Enteramin
Enteramine
8Histamine H1 AntagonistsPhase 3782
9AntipruriticsPhase 3864
10Anti-Allergic AgentsPhase 31490
11Dermatologic AgentsPhase 35674
12Gastrointestinal AgentsPhase 38109
13Histamine AntagonistsPhase 3946
14Protein Kinase InhibitorsPhase 23612
15Imatinib MesylatePhase 2594123596
16ColaNutraceutical1881

Interventional clinical trials:

idNameStatusNCT IDPhase
1Cyproheptadine in Preventing Weight Loss in Children Receiving Chemotherapy for CancerTerminatedNCT01132547Phase 3
2Phase II Study of Imatinib Mesylate in Patients With Life Threatening Malignant Rare DiseasesCompletedNCT00154388Phase 2
3Study of BLU-285 in Patients With Advanced Systemic Mastocytosis (advSM) and Relapsed or Refractory Myeloid MalignanciesRecruitingNCT02561988Phase 1
4Study of Information Received About Fertility and Infertility in Patients Who Have Finished Treatment for CancerUnknown statusNCT01295463
5Evaluation of Patient Satisfaction With and Acceptance of Their Totally-implanted Central Venous CatheterTerminatedNCT01616537
6Heparin or M-EDTA in Preventing Catheter-Related Infections and Blockages in Patients at High Risk for a Catheter-Related InfectionWithdrawnNCT00378781

Search NIH Clinical Center for Mast-Cell Sarcoma


Cochrane evidence based reviews: mast-cell sarcoma

Genetic Tests for Mast-Cell Sarcoma

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Anatomical Context for Mast-Cell Sarcoma

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MalaCards organs/tissues related to Mast-Cell Sarcoma:

35
Skin, Myeloid, Colon, Bone, Uterus, Small intestine, Bone marrow

Animal Models for Mast-Cell Sarcoma or affiliated genes

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MGI Mouse Phenotypes related to Mast-Cell Sarcoma:

40
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00020069.1CCR5, CXCR4, KIT, KITLG, PDGFRA, PTPRC
2MP:00053698.7ABL1, CCR5, CXCR4, KIT, MPO, PDGFRA
3MP:00053888.7ABL1, CXCR4, KIT, MGEA5, PDGFRA, PTPRC
4MP:00053818.4ABL1, CCR5, CXCR4, KIT, KITLG, PDGFRA
5MP:00053857.8ABL1, ANPEP, CCR5, CXCR4, KIT, KITLG
6MP:00053875.8ABL1, ANPEP, C5AR1, CCR5, CMA1, CXCR4
7MP:00053975.8ABL1, ANPEP, C5AR1, CCR5, CMA1, CXCR4

Publications for Mast-Cell Sarcoma

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Articles related to Mast-Cell Sarcoma:

(show all 27)
idTitleAuthorsYear
1
Mast cell sarcoma: new cases and literature review. (27602777)
2016
2
Anaplastic mast cell sarcoma: a unique pathologic entity in mastocytosis. (27808598)
2016
3
Mast cell sarcoma: clinical management. (24745684)
2014
4
Mast cell sarcoma in an infant: a case report and review of the literature. (23211696)
2013
5
Mast cell sarcoma: a rare and potentially under-recognized diagnostic entity with specific therapeutic implications. (23196796)
2013
6
Mast cell sarcoma: a rare and aggressive entity--report of two cases and review of the literature. (23129735)
2013
7
Pediatric mast cell sarcoma of temporal bone with novel L799F (2395 C>T) KIT mutation, mimicking histiocytic neoplasm. (23388130)
2013
8
Mast cell sarcoma mimicking metastatic colon carcinoma. (24141335)
2013
9
Mast cell sarcoma with megakaryocytic differentiation in a calf. (22813945)
2012
10
Malignant transformation of mastocytoma developed on skin mastocytosis into cutaneous mast cell sarcoma. (22498828)
2012
11
Mast cell sarcoma of the scalp: the first sign of undisclosed systemic mastocytosis? (22963840)
2012
12
Successful treatment of mast cell sarcoma of the uterus with imatinib. (22020400)
2011
13
Mast cell sarcoma of the small intestine: a case report. (21778298)
2011
14
Mast-cell sarcoma of the tibia. (17405977)
2007
15
Morphologic and immunophenotypic properties of neoplastic cells in a case of mast cell sarcoma. (12826896)
2003
16
Characterization of novel stem cell factor responsive human mast cell lines LAD 1 and 2 established from a patient with mast cell sarcoma/leukemia; activation following aggregation of FcepsilonRI or FcgammaRI. (12801524)
2003
17
Temporary response of localized intracranial mast cell sarcoma to combination chemotherapy. (11216707)
2001
18
Mast cell sarcoma with tissue eosinophilia arising in the ascending colon. (10430280)
1999
19
Association of bone marrow mastocytosis with extremely immature extramedullary mast cell sarcoma]. (9273545)
1997
20
What is your diagnosis? Mast cell sarcoma. (9097238)
1997
21
Brief communication, Histopathology of a spontaneously developing mast cell sarcoma in a Wistar rat. (8736393)
1996
22
Use of hyperthermia and radiotherapy in treatment of a large mast cell sarcoma in a dog. (3145930)
1988
23
Mast cell sarcoma of the larynx. (3088063)
1986
24
Mast cell sarcoma of the larynx in a dog: a case report. (104092)
1979
25
Multiple genital neoplasia (mast cell sarcoma, seminoma, and sertoli cell tumor) in a dog. (13306668)
1956
26
Preliminary observations on the use of cortisone in canine mast cell sarcoma. (13108793)
1953
27
Neoplastic diseases of dogs; mast cell sarcoma, lymphosarcoma, histiocytoma. (18118928)
1948

Variations for Mast-Cell Sarcoma

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Expression for genes affiliated with Mast-Cell Sarcoma

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Search GEO for disease gene expression data for Mast-Cell Sarcoma.

Pathways for genes affiliated with Mast-Cell Sarcoma

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Pathways related to Mast-Cell Sarcoma according to GeneCards Suite gene sharing:

(show all 16)
idSuper pathwaysScoreTop Affiliating Genes
110.1KIT, KITLG
29.6IFNA2, KIT, PTPRC
39.6CXCR4, PDGFRA, VIM
49.4ANPEP, KIT, KITLG, MPO
59.2ABL1, KIT, KITLG, PDGFRA
69.2CCR5, CXCR4, KIT, PDGFRA
79.2CXCR4, KIT, KITLG, MPO, PTPRC
89.1ANPEP, CXCR4, KIT, PDGFRA
98.8ANPEP, CD2, CSF2RA, FCGR1A, KIT, KITLG
108.8CXCR4, KIT, PTPRC, TNFRSF8
118.6ABL1, CSF2RA, CXCR4, KIT, KITLG, PDGFRA
128.5ANPEP, CD2, IFNA2, KIT, KITLG, MPO
13
Show member pathways
7.7CCR5, CD2, CSF2RA, CXCR4, KIT, KITLG
14
Show member pathways
7.4CCR5, CD2, CSF2RA, CXCR4, KIT, KITLG
15
Show member pathways
7.3CCR5, CD2, CSF2RA, CXCR4, IFNA2, KIT
16
Show member pathways
7.0ABL1, CCR5, CD2, CSF2RA, CXCR4, KIT

GO Terms for genes affiliated with Mast-Cell Sarcoma

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Cellular components related to Mast-Cell Sarcoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1cell leading edgeGO:00312529.6ABL1, CXCR4, VIM
2external side of plasma membraneGO:00098979.1ANPEP, CCR5, CD2, KIT, PTPRC
3cell surfaceGO:00099868.6C5AR1, CCR5, CD2, CXCR4, KIT, PTPRC
4integral component of plasma membraneGO:00058877.3ANPEP, C5AR1, CCR5, CD2, CSF2RA, PDGFRA

Biological processes related to Mast-Cell Sarcoma according to GeneCards Suite gene sharing:

(show all 20)
idNameGO IDScoreTop Affiliating Genes
1embryonic hemopoiesisGO:003516210.7KIT, KITLG
2ectopic germ cell programmed cell deathGO:003523410.7KIT, KITLG
3positive regulation of phospholipase C activityGO:001086310.7KIT, PDGFRA
4Bergmann glial cell differentiationGO:006002010.4ABL1, VIM
5phosphatidylinositol phosphorylationGO:004685410.3KIT, KITLG, PDGFRA
6regulation of phosphatidylinositol 3-kinase signalingGO:001406610.3KIT, KITLG, PDGFRA
7positive regulation of interferon-gamma secretionGO:190271510.3ABL1, CD2
8phosphatidylinositol-mediated signalingGO:004801510.3KIT, KITLG, PDGFRA
9fusion of virus membrane with host plasma membraneGO:001906410.0CCR5, CXCR4
10regulation of chemotaxisGO:005092010.0CXCR4, PDGFRA
11entry into host cellGO:003026010.0CCR5, CXCR4
12dendritic cell chemotaxisGO:000240710.0CCR5, CXCR4
13B cell proliferationGO:00421009.8ABL1, IFNA2, PTPRC
14peptidyl-tyrosine phosphorylationGO:00181089.6ABL1, CSF2RA, KIT, PDGFRA
15activation of MAPK activityGO:00001879.4C5AR1, CXCR4, KIT
16cell surface receptor signaling pathwayGO:00071669.3CCR5, CD2, IFNA2, PTPRC
17MAPK cascadeGO:00001658.9CCR5, CSF2RA, KIT, KITLG, PDGFRA
18positive regulation of cytosolic calcium ion concentrationGO:00072048.6ABL1, C5AR1, CCR5, CXCR4, PDGFRA
19immune responseGO:00069558.3C5AR1, CCR5, CMA1, FCGR1A, TNFRSF8
20inflammatory responseGO:00069548.1C5AR1, CCR5, CXCR4, IFNA2, KIT, TNFRSF8

Molecular functions related to Mast-Cell Sarcoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1phosphatidylinositol-4,5-bisphosphate 3-kinase activityGO:004693410.1KIT, KITLG, PDGFRA
2Ras guanyl-nucleotide exchange factor activityGO:00050889.2CSF2RA, KIT, KITLG, PDGFRA
3virus receptor activityGO:00016189.2ANPEP, CCR5, CXCR4

Sources for Mast-Cell Sarcoma

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
26GTR
27HGMD
28HMDB
29ICD10
30ICD10 via Orphanet
31ICD9CM
32IUPHAR
33KEGG
36MedGen
38MeSH
39MESH via Orphanet
40MGI
43NCI
44NCIt
45NDF-RT
48NINDS
49Novoseek
51OMIM
52OMIM via Orphanet
56PubMed
57QIAGEN
62SNOMED-CT via Orphanet
66Tumor Gene Family of Databases
67UMLS
68UMLS via Orphanet