MCID: MST005
MIFTS: 43

Mastitis malady

Reproductive diseases, Endocrine diseases categories

Summaries for Mastitis

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Wikipedia:63 Mastitis is the inflammation of breast tissue.S. aureus is the most common etiological organism... more...

MalaCards based summary: Mastitis, also known as inflammatory disorder of breast, is related to systemic lupus erythematosus and tuberculosis. An important gene associated with Mastitis is HP (haptoglobin), and among its related pathways is amb2 Integrin signaling. The compounds probucol and deferoxamine have been mentioned in the context of this disorder. Affiliated tissues include breast, testes and neutrophil.

Aliases & Classifications for Mastitis

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Sources:
9Disease Ontology, 11DISEASES, 43Novoseek, 60UMLS, 55SNOMED-CT, 27ICD9CM, 33MeSH, 38NCIt, 25ICD10
See all sources

Mastitis, Aliases & Descriptions:

Name: Mastitis 9 11 43 60
Inflammatory Disorder of Breast 9 60
Inflammation of Non-Human Mammary Gland 60
Inflammatory Disease of Breast 9
 
Inflammatory Breast Disease 9
Breast Inflammation Nos 9
Infectious Mastitis 60


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Reproductive diseases, Endocrine diseases


External Ids:

Disease Ontology9 DOID:10690
ICD9CM27 611.0
MeSH33 D008413
NCIt38 C53662
ICD1025 N61

Related Diseases for Mastitis

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Diseases related to Mastitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 90)
idRelated DiseaseScoreTop Affiliating Genes
1systemic lupus erythematosus30.1LTF, NOD2, VTN
2tuberculosis29.9LYZ, BPI, HP, NOD2
3arthritis29.6LYZ, VTN, HP, NOD2, LTF
4granulomatous mastitis11.1
5eosinophilic mastitis10.4
6breast cancer10.3
7neonatal infective mastitis10.3
8pouchitis10.2LTF, NOD2
9inflammatory breast carcinoma10.2
10pneumonia10.2
11spondyloarthropathy 110.2NOD2, HP
12membranous glomerulonephritis, antenatal10.2VTN, HP
13prolactinoma10.2
14diabetic mastopathy10.2
15mycobacterium abscessus10.2
16mycobacterium fortuitum10.2
17periodontal disease10.2LTF, LYZ
18cholangitis, primary sclerosing10.1BPI, LTF
19hepatitis c10.1LTF, HP
20nephrotic syndrome10.1HP, VTN
21arthropathy10.1NOD2, BPI
22hypersensitivity reaction type ii disease10.1LTF, LYZ
23rhinotracheitis10.1
24calciphylaxis10.1
25breast lymphoma10.1
26toxic shock syndrome10.1
27lupus erythematosus10.1
28vasculitis10.1BPI, LTF
29proteinuria10.1HP, VTN
30microvascular complications of diabetes 510.0VTN, BPI
31kidney disease10.0LYZ, HP
32reactive arthritis10.0LTF, HP, BPI
33crohn's disease10.0LTF, NOD2, LYZ
34cystic fibrosis10.0LTF, HP, BPI
35psoriasis10.0VTN, NOD2, LTF
36colitis10.0LTF, NOD2, BPI
37sarcoidosis 110.0LYZ, VTN, NOD2
38ulcerative colitis10.0LTF, NOD2, BPI
39inflammatory bowel disease10.0LTF, NOD2, BPI
40atherosclerosis9.9NOD2, HP, VTN
41endometriosis9.9HP, VTN
42galactosemia9.9HP, VTN, BPI
43liver cirrhosis9.9LTF, VTN, BPI
44hyperprolactinemia9.9
45aspergillosis9.9
46leprosy9.9
47leukocyte adhesion deficiency9.9
48hiv-19.9
49breast reconstruction9.9
50hepatitis9.9

Graphical network of the top 20 diseases related to Mastitis:



Diseases related to mastitis

Symptoms for Mastitis

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Drugs & Therapeutics for Mastitis

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Drug clinical trials:

Search ClinicalTrials for Mastitis

Search NIH Clinical Center for Mastitis

Genetic Tests for Mastitis

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Anatomical Context for Mastitis

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MalaCards organs/tissues related to Mastitis:

31
Breast, Testes, Neutrophil, Liver, Pituitary

Animal Models for Mastitis or affiliated genes

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Publications for Mastitis

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Articles related to Mastitis:

(show top 50)    (show all 755)
idTitleAuthorsYear
1
Molecular characteristics of bap-positive Staphylococcus aureus strains from dairy cow mastitis. (25850658)
2015
2
Pulsed-Field Gel Electrophoresis (PFGE): Application in Population Structure Studies of Bovine Mastitis-Causing Streptococci. (25399106)
2015
3
The association between occurrence and severity of subclinical and clinical mastitis on pregnancies per artificial insemination at first service of Holstein cows. (25795486)
2015
4
Molecular and bacteriological investigation of subclinical mastitis caused by Staphylococcus aureus and Streptococcus agalactiae in domestic bovids from Ismailia, Egypt. (25374070)
2014
5
Granulomatous mastitis: changing clinical and imaging features with image-guided biopsy correlation. (24962828)
2014
6
Effects of clinical mastitis on reproductive and milk performance of Holstein cows in Morocco. (25367278)
2014
7
Comparison of the effect of surgical and medical therapy for the treatment of idiopathic granulomatous mastitis. (25002895)
2014
8
Bilateral Eosinophilic Mastitis: An uncommon unheard entity. (25171213)
2014
9
Bovine mastitis: frontiers in immunogenetics. (25339959)
2014
10
Staphylococcus aureus from 152 cases of bovine, ovine and caprine mastitis investigated by Multiple-locus variable number of tandem repeat analysis (MLVA). (25315988)
2014
11
Predictive value of prepartum serum metabolites for incidence of clinical and subclinical mastitis in grazing primiparous Holstein cows. (23526122)
2013
12
Idiopathic granulomatous mastitis: an autoimmune disease? (24082849)
2013
13
Tubercular mastitis - a great masquerader. (23354799)
2013
14
Trematode infections in pregnant ewes can predispose to mastitis during the subsequent lactation period. (24331730)
2013
15
Evaluation of PCR electrospray-ionization mass spectrometry for rapid molecular diagnosis of bovine mastitis. (23587378)
2013
16
Efficiency of two commercial on-farm pasteurizers for inactivation of mastitis pathogens in milk intended for feeding. of calves. (23367666)
2013
17
Evaluation of therapeutic potential of nanosilver particles synthesised using aloin in experimental murine mastitis model. (24028805)
2013
18
Immunotherapy of mastitis. (23523288)
2013
19
Coagulase-negative staphylococci (CNS) as an aetiological factor of mastitis in cows. (24195283)
2013
20
Stem cell research: a novel boulevard towards improved bovine mastitis management. (23983615)
2013
21
Incidence of subclinical mastitis in Dutch dairy heifers in the first 100 days in lactation and associated risk factors. (22541474)
2012
22
The relationship between the variants of the bovine MBL2 gene and milk production traits, mastitis, serum MBL-C levels and complement activity. (22771198)
2012
23
Herd characteristics and cow-level factors associated with Prototheca mastitis on dairy farms in Ontario, Canada. (22884347)
2012
24
Biofilm production and presence of ica and bap genes in Staphylococcus aureus strains isolated from cows with mastitis in the eastern Poland. (22708349)
2012
25
Serum amyloid A isoforms in serum and milk from cows with Staphylococcus aureus subclinical mastitis. (22100192)
2012
26
Bovine mastitis: the diagnostic properties of a PCR-based assay to monitor the Staphylococcus aureus genotype B status of a herd, using bulk tank milk. (22720925)
2012
27
Granulomatous mastitis: is it an autoimmune disease? Diagnostic and therapeutic dilemmas. (22068681)
2012
28
In vitro antimicrobial activity of Combretum molle (Combretaceae) against Staphylococcus aureus and Streptococcus agalactiae isolated from crossbred dairy cows with clinical mastitis. (22207479)
2012
29
Milk microbiome signatures of subclinical mastitis-affected cattle analysed by shotgun sequencing. (22277077)
2012
30
Effects of Jin-Ying-Tang on Staphylococcus aureus-induced mastitis in rabbit. (22303901)
2012
31
Molecular cloning, promoter analysis, SNP detection of Clusterin gene and their associations with mastitis in Chinese Holstein cows. (21667239)
2012
32
Improved identification including MALDI-TOF mass spectrometry analysis of group D streptococci from bovine mastitis and subsequent molecular characterization of corresponding Enterococcus faecalis and Enterococcus faecium isolates. (22677481)
2012
33
Histone H3K14 and H4K8 hyperacetylation is associated with Escherichia coli-induced mastitis in mice. (22419123)
2012
34
Taurine attenuates Streptococcus uberis-induced mastitis in rats by increasing T regulatory cells. (21809074)
2012
35
Genotypic characterization and evaluation of an antibiotic resistance of Trueperella pyogenes (Arcanobacterium pyogenes) isolated from milk of dairy cows with clinical mastitis. (22868181)
2012
36
Phenotypic and genotypic characterization of Streptococcus uberis isolated from bovine subclinical mastitis in Argentinean dairy farms. (22430996)
2011
37
The effect of recurrent episodes of clinical mastitis caused by gram-positive and gram-negative bacteria and other organisms on mortality and culling in Holstein dairy cows. (21943738)
2011
38
Multiplex PCR assay for species identification of bovine mastitis pathogens. (21972842)
2011
39
Lupus mastitis in systemic lupus erythematosus: a rare condition requiring a minimally invasive diagnostic approach. (22230423)
2011
40
Prevalence and molecular mechanism of macrolide and lincosamide resistance in staphylococci isolated from subclinical bovine mastitis in Turkey. (21799300)
2011
41
A HACCP-based approach to mastitis control in dairy herds. Part 2: Implementation and evaluation. (21777494)
2011
42
Erythema nodosum associated with granulomatous mastitis: report of two cases. (19701754)
2010
43
Idiopathic granulomatous mastitis in Hispanic women - Indiana, 2006-2008. (19959984)
2009
44
Idiopathic granulomatous mastitis: a heterogeneous disease with variable clinical presentation. (17541683)
2007
45
Idiopathic granulomatous mastitis: a case successfully treated with a minimum dose of a steroid. (16124160)
2005
46
Delayed neutrophil apoptosis in bovine subclinical mastitis. (15545372)
2004
47
Phage conversion of exfoliative toxin A in Staphylococcus aureus isolated from cows with mastitis. (14516710)
2003
48
Occurrence of the blaZ gene in penicillin resistant Staphylococcus aureus isolated from bovine mastitis in Denmark. (10605145)
1999
49
Caprine mastitis due to aspergillosis and zygomycosis: a pathological and immunohistochemical study. (8920218)
1996
50
Isolation of Mycoplasma agalactiae var bovis and infectious bovine rhinotracheitis virus from an outbreak of mastitis in France. (4375340)
1974

Variations for Mastitis

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Expression for genes affiliated with Mastitis

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Search GEO for disease gene expression data for Mastitis.

Pathways for genes affiliated with Mastitis

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Pathways related to Mastitis according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.6HP, VTN

Compounds for genes affiliated with Mastitis

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Compounds related to Mastitis according to GeneCards Suite gene sharing:

(show all 48)
idCompoundScoreTop Affiliating Genes
1probucol43 1211.1HP, LTF
2deferoxamine43 1211.1HP, LTF
3lactulose4310.0LTF, NOD2
4rifampicin43 28 5912.0LTF, HP
5lactose43 1211.0LTF, HP
6ribavirin43 49 1212.0LTF, HP
7pentoxifylline43 1211.0HP, LTF
8sodium chlorate4310.0LTF, VTN
9vitamin b124310.0LTF, HP
10pmma4310.0LTF, VTN
11fucoidan439.9LTF, VTN
12neopterin439.9LTF, HP
13cytochalasin b439.9LTF, VTN
14dextran sulfate439.9LTF, VTN
15n-formylmethionyl-leucylphenylalanine439.9VTN, LTF
16tetrapeptide439.9VTN, LTF
17kininogen439.9VTN, HP
18polymyxin b439.8LTF, BPI
19chloroquine43 2 49 28 1213.8VTN, HP
20anti-fungal439.8LTF, BPI
21polyethylene glycol439.8HP, VTN
22chondroitin sulfate43 2410.8VTN, LTF
23latex439.7VTN, LTF
24sodium dodecylsulfate439.7HP, VTN
25citrate439.7LTF, HP
26sialic acid439.6VTN, HP, LTF
27hyaluronic acid43 2410.6VTN, HP, LTF
28nacl439.6LYZ, HP, LTF
29fibrinogen439.6VTN, HP, LTF
30pge2439.5LTF, HP, VTN
31aspartate439.5LTF, HP, VTN
32actinomycin d439.5LTF, HP, BPI
33cytochalasin d43 5910.4LTF, VTN
34urea43 24 1211.4HP, VTN, BPI
35creatinine439.4LTF, HP, BPI
36lactate439.3BPI, VTN, HP
37carbohydrates439.3FUT2, HP, LTF
38dexamethasone43 49 28 1212.2LTF, HP, VTN
39cholesterol43 28 24 1212.1HP, VTN, BPI
40endotoxin439.1LTF, NOD2, HP, BPI
41nitric oxide43 24 1211.0BPI, HP, NOD2
42polysaccharide439.0BPI, VTN, HP, LTF
43heparin43 28 24 1212.0BPI, VTN, HP, LTF
44vegf439.0LTF, HP, VTN, BPI
45alanine439.0LTF, HP, VTN, BPI
46cysteine438.9LTF, HP, VTN, BPI
47glutamate438.9LTF, HP, VTN
48serine438.5LTF, NOD2, HP, VTN, BPI

GO Terms for genes affiliated with Mastitis

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Cellular components related to Mastitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1blood microparticleGO:00725629.6HP, VTN
2extracellular spaceGO:00056158.5LYZ, VTN, HP, LTF
3extracellular regionGO:00055768.3LTF, HP, VTN, LYZ
4extracellular vesicular exosomeGO:00700627.2LTF, HP, VTN, BPI, LYZ, FUT2

Biological processes related to Mastitis according to GeneCards Suite gene sharing:

(show all 8)
idNameGO IDScoreTop Affiliating Genes
1innate immune response in mucosaGO:00022279.8LTF, NOD2
2defense responseGO:00069529.6NOD2, HP
3positive regulation of I-kappaB kinase/NF-kappaB signalingGO:00431239.6LTF, NOD2
4retina homeostasisGO:00018959.6LYZ, LTF
5negative regulation of tumor necrosis factor productionGO:00327209.5NOD2, BPI
6positive regulation of peptidyl-tyrosine phosphorylationGO:00507319.4NOD2, VTN
7positive regulation of NF-kappaB transcription factor activityGO:00510929.3LTF, NOD2
8defense response to bacteriumGO:00427428.7NOD2, HP, BPI, LYZ

Molecular functions related to Mastitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1heparin bindingGO:00082019.5LTF, VTN

Products for genes affiliated with Mastitis

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Sources for Mastitis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet