Aliases & Classifications for Mastitis

MalaCards integrated aliases for Mastitis:

Name: Mastitis 12 52 42 14 69
Inflammation of Non-Human Mammary Gland 69
Inflammatory Disorder of Breast 69
Inflammatory Disease of Breast 12
Inflammatory Breast Disease 12
Breast Inflammation 12

Classifications:



External Ids:

Disease Ontology 12 DOID:10690
MeSH 42 D008413
NCIt 47 C53662
ICD10 33 N61
UMLS 69 C0024894

Summaries for Mastitis

MalaCards based summary : Mastitis, also known as inflammation of non-human mammary gland, is related to lymphoma and pasteurellosis, and has symptoms including signs and symptoms in breast An important gene associated with Mastitis is LTF (Lactotransferrin), and among its related pathways/superpathways are Innate Immune System and Akt Signaling. The drugs Hydrocortisone and Histamine have been mentioned in the context of this disorder. Affiliated tissues include breast, testes and neutrophil, and related phenotypes are hematopoietic system and homeostasis/metabolism

Wikipedia : 72 Mastitis (also called mammitis) is inflammation of breast or udder tissue usually due to infection.... more...

Related Diseases for Mastitis

Diseases related to Mastitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 192)
id Related Disease Score Top Affiliating Genes
1 lymphoma 30.0 ALB IL17A IL6
2 pasteurellosis 30.0 CSF2 CXCL8 IL6
3 breast disease 29.8 CXCL8 IL6 OXT
4 churg-strauss syndrome 29.7 CXCL8 ICAM1 IL17A
5 systemic lupus erythematosus 28.8 ALB CCL5 ICAM1 IL17A IL6
6 granulomatous mastitis 12.3
7 granulomatous lobular mastitis 12.2
8 neonatal infective mastitis 11.9
9 eosinophilic mastitis 11.9
10 breast abscess 11.2
11 toxic shock syndrome 11.1
12 inflammatory breast carcinoma 11.1
13 diabetic mastopathy 11.1
14 mycobacterium malmoense 10.8 CXCL8 TLR2
15 smarca4-deficient sarcoma of thorax 10.7 CCL5 IL6
16 oculomotor nerve paralysis 10.7 CXCL8 IL6
17 common peroneal nerve lesion 10.7 CXCL8 IL6
18 congenital insensitivity to pain with hyperhidrosis 10.6 CXCL8 LTF NOD2
19 mycobacterium xenopi 10.6 CXCL8 TLR2
20 bullous retinoschisis 10.6 CXCL8 IL6 SLPI
21 mikulicz disease 10.6 ALB IL6 LTF
22 congenital diaphragmatic hernia 10.6 CXCL8 ICAM1
23 palmoplantar keratosis 10.6 CXCL8 IL6 TLR2
24 atrophy of prostate 10.6 CXCL8 IL6 TLR2
25 allergic bronchopulmonary aspergillosis 10.6 ALB CXCL8 IL6
26 lymphangiectasia, intestinal 10.6 CSF2 CXCL8 LTF
27 breast papillary carcinoma 10.6 ALB CXCL8 IL6
28 germ cell and embryonal cancer 10.6 CXCL8 IL6 LTF
29 neutrophil-specific granule deficiency 10.6 IL17A TLR2
30 cytomegalovirus retinitis 10.6 CXCL8 ICAM1
31 adenocarcinoid tumor 10.6 CXCL8 IL6 LBP
32 choroiditis 10.6 ALB CXCL8 IL6
33 sheehan syndrome 10.5 ALB CXCL8 TLR2
34 dentinogenesis imperfecta 10.5 ALB CXCL8 IL6
35 ovarian mucinous adenofibroma 10.5 CCL5 CXCL8 IL6
36 pneumoconiosis 10.5 CCL5 CXCL8 IL6
37 mucocutaneous leishmaniasis 10.5 ALB CXCL8 TLR2
38 paranasal sinus sarcoma 10.5 ALB CXCL8 IL6
39 nasal cavity carcinoma in situ 10.5 ALB CXCL8 SLPI
40 neonatal marfan syndrome 10.5 CXCL8 IL17A
41 keratomalacia 10.5 CXCL8 IL6 TLR2
42 colon adenocarcinoma 10.5 ALB CXCL8 IL6
43 tricho onychic dysplasia 10.5 CXCL8 IL17A IL6
44 late yaws 10.5 ALB CCL5 IL6
45 acute myeloblastic leukemia without maturation 10.5 CSF2 CXCL8 IL6
46 burn scar 10.5 CXCL8 IL17A IL6
47 fanconi syndrome 10.5 CCL5 CSF2 TLR2
48 uterine adnexa cancer 10.4 IL17A IL6 TLR2
49 epidermolysis bullosa acquisita 10.4 ALB CCL5 IL17A
50 inner ear disease 10.4 CCL5 CXCL8 IL6

Comorbidity relations with Mastitis via Phenotypic Disease Network (PDN):


Acute Cystitis Fat Necrosis of Breast
Female Breast Cancer Hypertension, Essential
Microglandular Adenosis

Graphical network of the top 20 diseases related to Mastitis:



Diseases related to Mastitis

Symptoms & Phenotypes for Mastitis

UMLS symptoms related to Mastitis:


signs and symptoms in breast

MGI Mouse Phenotypes related to Mastitis:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 10.22 CCL5 CP CSF2 CXCL6 HP ICAM1
2 homeostasis/metabolism MP:0005376 10.21 ALB CP CSF2 CXCL6 HP ICAM1
3 endocrine/exocrine gland MP:0005379 10.13 ICAM1 IL17A IL6 LALBA OXT TLR2
4 immune system MP:0005387 10.13 CXCL6 HP ICAM1 IL17A IL6 LBP
5 digestive/alimentary MP:0005381 10 ALB ICAM1 IL17A IL6 NOD2 OXT
6 integument MP:0010771 9.86 CSF2 CSN2 CSN3 ICAM1 IL6 LALBA
7 liver/biliary system MP:0005370 9.7 CP HP IL6 LBP LTF TLR2
8 neoplasm MP:0002006 9.5 TLR2 ALB CSF2 HP ICAM1 IL6
9 renal/urinary system MP:0005367 9.17 ALB CSF2 HP IL17A IL6 OXT

Drugs & Therapeutics for Mastitis

Drugs for Mastitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 95)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Hydrocortisone Approved, Vet_approved Phase 4 50-23-7 5754 657311
2
Histamine Approved, Investigational Phase 4 75614-87-8, 51-45-6 774
3
Butyric Acid Experimental Phase 4 107-92-6 264
4 Cortisol succinate Phase 4
5 Hydrocortisone 17-butyrate 21-propionate Phase 4
6 Hydrocortisone acetate Phase 4
7 Anti-Inflammatory Agents Phase 4
8 Dermatologic Agents Phase 4
9 Histamine Antagonists Phase 4
10
Histamine Phosphate Phase 4 51-74-1 65513
11 Hydrocortisone-17-butyrate Phase 4
12 Neurotransmitter Agents Phase 4
13
Amoxicillin Approved, Vet_approved Phase 2, Phase 3 26787-78-0 33613 2171
14
Cloxacillin Approved, Vet_approved Phase 2, Phase 3 61-72-3 6098
15
Selenium Approved, Vet_approved Phase 3 7782-49-2
16
Hydroxocobalamin Approved Phase 3 13422-51-0 11953898 5460373 44475014
17
Azithromycin Approved Phase 3 83905-01-5 55185 53477736 447043
18
B-Carotene Approved, Nutraceutical Phase 3 7235-40-7 5280489
19
Cyanocobalamin Approved, Nutraceutical Phase 3 68-19-9 44176380
20
Folic Acid Approved, Nutraceutical, Vet_approved Phase 3 59-30-3 6037
21
leucovorin Approved, Nutraceutical Phase 3 58-05-9 143 6006
22
Niacin Approved, Investigational, Nutraceutical Phase 3 59-67-6 938
23
Nicotinamide Approved, Nutraceutical Phase 3 98-92-0 936
24
Pyridoxal Approved, Nutraceutical Phase 3 66-72-8 1050
25
Pyridoxine Approved, Nutraceutical, Vet_approved Phase 3 65-23-6 1054
26
Riboflavin Approved, Nutraceutical, Vet_approved Phase 3 83-88-5 493570
27
Thiamine Approved, Nutraceutical, Vet_approved Phase 3 59-43-8 1130
28 Tocopherol Approved, Nutraceutical Phase 3,Phase 2
29
Vitamin A Approved, Nutraceutical, Vet_approved Phase 3 11103-57-4, 68-26-8 445354
30
Vitamin C Approved, Nutraceutical Phase 3 50-81-7 5785 54670067
31
Vitamin E Approved, Nutraceutical, Vet_approved Phase 3,Phase 2 59-02-9 14985
32 Anti-Bacterial Agents Phase 2, Phase 3
33 Antibiotics, Antitubercular Phase 2, Phase 3
34 Anti-Infective Agents Phase 2, Phase 3
35 Antitubercular Agents Phase 2, Phase 3
36 beta-Lactamase Inhibitors Phase 2, Phase 3
37 beta-Lactams Phase 2, Phase 3
38 Clavulanic Acid Phase 2, Phase 3
39 Lactams Phase 2, Phase 3
40 Antioxidants Phase 3,Phase 2
41 Micronutrients Phase 3,Phase 2
42 Protective Agents Phase 3,Phase 2
43 Trace Elements Phase 3,Phase 2
44 Carotenoids Phase 3
45 Nicotinic Acids Phase 3
46 Retinol palmitate Phase 3
47 Tocopherols Phase 3,Phase 2
48 Tocotrienols Phase 3,Phase 2
49 Vitamin B 12 Phase 3
50 Vitamin B 6 Phase 3

Interventional clinical trials:

(show all 19)

id Name Status NCT ID Phase Drugs
1 Medical and Surgical Treatment for Idiopathic Granulomatous Mastitis Recruiting NCT02959580 Phase 4 Hydrocortisone Butyrate
2 Use of Probiotic Lactobacilli for the Treatment of Lactational Mastitis Completed NCT00716183 Phase 2, Phase 3 Beta-lactam antibiotic
3 Partnership on Nutrition and HIV/AIDS Research in Tanzania: Exploratory Research Study on Selenium and HIV Infection Completed NCT00197561 Phase 3
4 Vitamins, Breastmilk HIV Shedding, and Child Health Completed NCT00197756 Phase 3
5 Pre-delivery Administration of Azithromycin to Prevent Neonatal Sepsis & Death Not yet recruiting NCT03199547 Phase 3 Azithromycin;Placebo Oral Tablet
6 Study of a Probiotic Strain to Prevent Mastitis and to Eradicate GBS Colonization Unknown status NCT01505361 Phase 1, Phase 2
7 The Use of Pentoxifylline and Vitamin E in the Treatment of Chronic Breast Pain Terminated NCT00188669 Phase 2 pentoxifylline;alpha-Tocopherol
8 Survey of Optical Values of the Breast Using Radiation-Free Pressure-Free Optical Scanning Unknown status NCT00671385
9 Evaluation of Lactobacillus Fermentum CECT5716 on the Incidence of Mastitis Completed NCT02203877
10 Staphylococcus Aureus Carrier Status in Breastfeeding Mothers and Infants and the Risk of Lactation Mastitis Completed NCT00620984
11 Global Effects of a Probiotic Strain on Lactating Women Completed NCT01124448
12 Study of Acupuncture and Care Interventions for the Treatment of Breast Inflammation During Breastfeeding Completed NCT00405158 Anti-pyretic medication, paracetamol;cefadroxil;penicillin;flucloxacillin
13 Nursing Education Intervention for Maternal Breastfeeding Completed NCT02106026
14 Painful Breastfeeding and Bacterial or Yeast Infection Completed NCT01631461
15 L.Fermentum CECT5716 in Treatment of Breast Pain Completed NCT02093338
16 Impact of Maternal Stress on Infant Stunting Completed NCT02755012
17 Acupuncture for Breast Engorgement During Lactation Recruiting NCT03230760
18 Ductal Lavage in Non-lactating Female Women With Mastitis Active, not recruiting NCT02794688
19 Granulomatous Mastitis Current Approach and Treatment Enrolling by invitation NCT02667132

Search NIH Clinical Center for Mastitis

Cochrane evidence based reviews: mastitis

Genetic Tests for Mastitis

Anatomical Context for Mastitis

MalaCards organs/tissues related to Mastitis:

39
Breast, Testes, Neutrophil, Colon, Pituitary, Liver, Bone

Publications for Mastitis

Articles related to Mastitis:

(show top 50) (show all 946)
id Title Authors Year
1
Selective, reliable blood and milk bio-markers for diagnosing clinical and subclinical bovine mastitis. ( 27915437 )
2017
2
Incidence of bovine clinical mastitis in Jammu region and antibiogram of isolated pathogens. ( 28919694 )
2017
3
In Vitro Assessment of the Probiotic Potential of Lactococcus lactis LMG 7930 against Ruminant Mastitis-Causing Pathogens. ( 28068371 )
2017
4
Is surgical excision necessary for the treatment of Granulomatous lobular mastitis? ( 28738795 )
2017
5
Induction of heme oxygenas-1 attenuates NLRP3 inflammasome activation in lipopolysaccharide-induced mastitis in mice. ( 28938188 )
2017
6
The microbiota of water buffalo milk during mastitis. ( 28926595 )
2017
7
Biofilm formation and antimicrobial resistance genes of coagulase-negative staphylococci isolated from cows with mastitis in Argentina. ( 28087612 )
2017
8
Bilateral Lupus Mastitis During Pregnancy. ( 28926462 )
2017
9
Prevalence of subclinical mastitis and associated risk factors at cow and herd level in dairy farms in North-West Ethiopia. ( 28903872 )
2017
10
Erythema nodosum in association with idiopathic granulomatous mastitis: a case series and review of the literature. ( 28271562 )
2017
11
Differential diagnosis of idiopathic granulomatous mastitis and breast cancer using acoustic radiation force impulse imaging. ( 27787642 )
2017
12
Lymphoepithelioma-Like Carcinoma of the Breast Mimicking Granulomatous Mastitis- Case Report and Review of the Literature ( 28749097 )
2017
13
Rifampicin for Idiopathic Granulomatous Lobular Mastitis: A Promising Alternative for Treatment. ( 28050664 )
2017
14
Idiopathic Granulomatous Mastitis: A Clinical Puzzle in Breast Lump Cases. ( 28764247 )
2017
15
Corrigendum to "Efficacy of a high free iodine barrier teat disinfectant for the prevention of naturally occurring new intramammary infections and clinical mastitis in dairy cows" (J. Dairy Sci. 100:3930-3939). ( 28923657 )
2017
16
Granulomatous Mastitis in a Transgender Patient. ( 28580069 )
2017
17
Medicinal Plants Based Products Tested on Pathogens Isolated from Mastitis Milk. ( 28869568 )
2017
18
Clinical and Cytological Spectrum of Granulomatous Mastitis and Utility of FNAC in Picking up Tubercular Mastitis: An Eight-Year Study. ( 28511395 )
2017
19
The effect of a cannula milk sampling technique on the microbiological diagnosis of bovine mastitis. ( 28911843 )
2017
20
Risperidone Induced Granulomatous Mastitis Secondary to Hyperprolactinemia in a Non-Pregnant Woman-A Rare Case Report in a Bipolar Disorder. ( 28273980 )
2017
21
Whole-Genome Sequence of Streptococcus parauberis Strain SP-llh, Isolated from Cows with Mastitis in Western China. ( 28082485 )
2017
22
Assessing the economic impact of an endemic disease: the case of mastitis. ( 28926014 )
2017
23
Effects of intramammary infusion of sage (Salvia officinalis) essential oil on milk somatic cell count, milk composition parameters and selected hematology and serum biochemical parameters in Awassi sheep with subclinical mastitis. ( 28919679 )
2017
24
Molecular Characterization of Extended-Spectrum I^-Lactamase-Producing Escherichia coli Isolates from Milk Samples of Dairy Cows with Mastitis in Bavaria, Germany. ( 28953418 )
2017
25
I^-defensins: An innate defense for bovine mastitis. ( 28919695 )
2017
26
On-the-spot mastitis cell counts from hand-held gadget. ( 28883119 )
2017
27
Idiopathic granulomatous mastitis associated with hyperprolactinemia: A nonoperative approach. ( 28845595 )
2017
28
Idiopathic granulomatous mastitis: an institutional experience. ( 28740959 )
2017
29
Differentiation between idiopathic granulomatous mastitis and malignant breast lesions using strain ratio on ultrasonic elastography. ( 28729183 )
2017
30
Mangiferin inhibits mastitis induced by LPS via suppressing NF-A,B and NLRP3 signaling pathways. ( 27984712 )
2017
31
Factors affecting the cost-effectiveness of on-farm culture prior to the treatment of clinical mastitis in dairy cows. ( 28903881 )
2017
32
Idiopathic granulomatous mastitis. A rare benign entitiy that can simulate breast cancer. ( 28733047 )
2017
33
Granulomatous mastitis: We need a useful classification system. ( 28864358 )
2017
34
A mouse mastitis model to study the effects of the intramammary infusion of a food-grade Lactococcus lactis strain. ( 28873396 )
2017
35
Indirect enzyme-linked immunosorbent assay method based on Streptococcus agalactiae rSip-Pgk-FbsA fusion protein for detection of bovine mastitis. ( 28865212 )
2017
36
Idiopathic granulomatous mastitis: A diagnostic and therapeutic challenge. ( 28739122 )
2017
37
Is idiopathic granulomatous mastitis a surgical disease? The jury is still out. ( 28856149 )
2017
38
Biofilm production and beta-lactamic resistance in Brazilian Staphylococcus aureus isolates from bovine mastitis. ( 27913076 )
2017
39
Short communication: Cow- and quarter-level milking indicators and their associations with clinical mastitis in an automatic milking system. ( 28918136 )
2017
40
Cystic neutrophilic granulomatous mastitis associated with Corynebacterium including Corynebacterium kroppenstedtii. ( 28442140 )
2017
41
Magnetic resonance imaging characteristics of granulomatous mastitis. ( 28364724 )
2017
42
Draft Genome Sequence of Staphylococcus aureus 1608, a Strain That Caused Toxic Mastitis in Twin Cows. ( 28057751 )
2017
43
The association between subclinical mastitis around calving and reproductive performance in grazing dairy cows. ( 28869109 )
2017
44
Pituitary Adenoma and Hyperprolactinemia Accompanied by Idiopathic Granulomatous Mastitis. ( 28321344 )
2017
45
Treatments for Idiopathic Granulomatous Mastitis: Systematic Review and Meta-Analysis. ( 28731822 )
2017
46
Steroids administered after vacuum-assisted biopsy in the management of idiopathic granulomatous mastitis. ( 28931582 )
2017
47
Exfoliation rate of mammary epithelial cells in milk on bovine mastitis caused by Staphylococcus aureus is associated with bacterial load. ( 28891152 )
2017
48
Follow-up of granulomatous mastitis with monitoring versus surgery. ( 28655119 )
2017
49
Granulomatous Lobular Mastitis Associated with Mycobacterium abscessus in South China: A Case Report and Review of the Literature. ( 28286681 )
2017
50
Factors related to recurrence of idiopathic granulomatous mastitis: what do we learn from a multicentre study? ( 28749045 )
2017

Variations for Mastitis

Expression for Mastitis

Search GEO for disease gene expression data for Mastitis.

Pathways for Mastitis

Pathways related to Mastitis according to GeneCards Suite gene sharing:

(show all 28)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
13.92 CCL5 CSF2 CXCL8 HP ICAM1 IL17A
2
Show member pathways
13.33 CCL5 CSF2 CXCL6 CXCL8 IL17A IL6
3
Show member pathways
13.25 CCL5 CSF2 CXCL8 ICAM1 IL17A IL6
4
Show member pathways
12.89 CCL5 CP CXCL8 IL6 NOD2 TLR2
5
Show member pathways
12.78 CCL5 CXCL8 IL6 LBP TLR2
6
Show member pathways
12.71 CCL5 CXCL8 ICAM1 IL6 TLR2
7
Show member pathways
12.18 CSF2 CXCL6 CXCL8 IL17A IL6 TLR2
8 12.14 IL6 LBP NOD2 TLR2
9
Show member pathways
12.09 CXCL8 IL6 LBP TLR2
10 11.89 CXCL8 ICAM1 IL17A IL6 LBP
11 11.84 CCL5 CSF2 ICAM1 IL6 NOD2
12
Show member pathways
11.81 IL17A IL6 TLR2
13 11.81 CSF2 CXCL8 IL6 TLR2
14 11.8 CXCL8 ICAM1 IL6
15 11.78 CXCL8 ICAM1 LBP
16 11.75 CSF2 CXCL8 IL6 LBP
17 11.67 CXCL6 CXCL8 IL6
18 11.62 ICAM1 IL6 TLR2
19 11.6 CCL5 CSF2 CXCL8 IL6
20
Show member pathways
11.58 CSF2 CXCL8 ICAM1 IL6
21 11.57 CSF2 CSN2 CXCL8 ICAM1 IL6
22 11.51 CXCL8 IL6 TLR2
23
Show member pathways
11.47 CSF2 CXCL6 CXCL8 ICAM1 IL17A IL6
24 11.45 CXCL8 ICAM1 IL6 TLR2
25 11.42 HP ICAM1 IL6
26 11.24 CCL5 CSF2 CXCL8 ICAM1 IL6
27 11.18 CCL5 CSF2 CXCL6 CXCL8 ICAM1 IL17A
28 11.03 CCL5 CSF2 CXCL6 CXCL8 IL17A IL6

GO Terms for Mastitis

Cellular components related to Mastitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.86 ALB CCL5 CP CSF2 CSN2 CSN3
2 extracellular space GO:0005615 9.55 ALB CCL5 CP CSF2 CSN2 CSN3
3 specific granule lumen GO:0035580 9.33 HP LTF SLPI

Biological processes related to Mastitis according to GeneCards Suite gene sharing:

(show all 37)
id Name GO ID Score Top Affiliating Genes
1 inflammatory response GO:0006954 9.95 CCL5 CXCL6 CXCL8 IL17A IL6 TLR2
2 cellular protein metabolic process GO:0044267 9.94 ALB CP IL6 LTF
3 positive regulation of ERK1 and ERK2 cascade GO:0070374 9.92 CCL5 ICAM1 IL6 NOD2
4 defense response GO:0006952 9.88 CXCL6 CXCL8 HP NOD2
5 cellular response to tumor necrosis factor GO:0071356 9.86 CCL5 CXCL8 ICAM1 IL6
6 response to lipopolysaccharide GO:0032496 9.85 ICAM1 IL6 LBP SLPI TLR2
7 chemokine-mediated signaling pathway GO:0070098 9.82 CCL5 CXCL6 CXCL8
8 response to insulin GO:0032868 9.81 ICAM1 IL6 TLR2
9 neutrophil chemotaxis GO:0030593 9.81 CCL5 CXCL6 CXCL8
10 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.8 CCL5 CSF2 IL6
11 positive regulation of epithelial cell proliferation GO:0050679 9.8 CCL5 IL6 NOD2
12 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.8 ICAM1 IL6 LTF NOD2 TLR2
13 positive regulation of tumor necrosis factor production GO:0032760 9.79 LBP NOD2 TLR2
14 negative regulation of viral genome replication GO:0045071 9.77 CCL5 LTF SLPI
15 immune response GO:0006955 9.76 CCL5 CSF2 CXCL6 CXCL8 IL17A IL6
16 acute-phase response GO:0006953 9.75 HP IL6 LBP
17 lipopolysaccharide-mediated signaling pathway GO:0031663 9.72 CCL5 LBP TLR2
18 positive regulation of neutrophil chemotaxis GO:0090023 9.71 CXCL6 CXCL8 LBP
19 positive regulation of interleukin-8 production GO:0032757 9.7 LBP NOD2 TLR2
20 defense response to Gram-positive bacterium GO:0050830 9.69 IL6 LBP TLR2
21 positive regulation of nitric-oxide synthase biosynthetic process GO:0051770 9.67 NOD2 TLR2
22 response to molecule of bacterial origin GO:0002237 9.67 CXCL8 TLR2
23 cellular response to nutrient levels GO:0031669 9.67 ICAM1 IL6
24 defense response to Gram-negative bacterium GO:0050829 9.67 IL6 LBP LTF
25 positive regulation of interleukin-6 production GO:0032755 9.67 IL6 LBP NOD2 TLR2
26 negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 9.66 CCL5 CXCL8
27 cellular response to lipoteichoic acid GO:0071223 9.66 LBP TLR2
28 neutrophil mediated immunity GO:0002446 9.65 CXCL6 IL6
29 positive regulation of toll-like receptor 4 signaling pathway GO:0034145 9.65 LBP LTF
30 cellular response to interleukin-1 GO:0071347 9.65 CCL5 CXCL8 ICAM1 IL17A IL6
31 negative regulation of macrophage apoptotic process GO:2000110 9.61 CCL5 NOD2
32 positive regulation of chemokine production GO:0032722 9.61 IL6 LBP TLR2
33 positive regulation of interleukin-23 production GO:0032747 9.6 CSF2 IL17A
34 cytokine secretion involved in immune response GO:0002374 9.57 NOD2 TLR2
35 neutrophil activation GO:0042119 9.5 CCL5 CXCL6 CXCL8
36 cellular response to lipopolysaccharide GO:0071222 9.43 CSF2 CXCL6 CXCL8 ICAM1 IL6 LBP
37 defense response to bacterium GO:0042742 9.17 CXCL6 HP LALBA LBP LTF NOD2

Molecular functions related to Mastitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 chemokine activity GO:0008009 9.33 CCL5 CXCL6 CXCL8
2 peptidoglycan binding GO:0042834 9.32 NOD2 TLR2
3 lipopeptide binding GO:0071723 9.26 LBP TLR2
4 lipopolysaccharide binding GO:0001530 9.13 LBP LTF TLR2
5 cytokine activity GO:0005125 9.1 CCL5 CSF2 CXCL6 CXCL8 IL17A IL6

Sources for Mastitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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