MCID: MST005
MIFTS: 49

Mastitis malady

Reproductive diseases category

Summaries for Mastitis

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63Wikipedia, 32MalaCards
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Wikipedia:63 Mastitis is the inflammation of breast tissue.S. aureus is the most common etiological organism... more...

MalaCards: Mastitis, also known as inflammatory disorder of breast, is related to pneumonia and toxic shock syndrome. An important gene associated with Mastitis is HP (haptoglobin), and among its related pathways are Selenium Pathway and Selenium Metabolism and Selenoproteins. The compounds exorphins and cmpa have been mentioned in the context of this disorder. Affiliated tissues include breast, testes and liver.

Aliases & Classifications for Mastitis

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8Disease Ontology, 10DISEASES, 44Novoseek, 60UMLS, 34MeSH, 56SNOMED-CT, 39NCIt, 27ICD9CM, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Reproductive diseases


Aliases & Descriptions:

mastitis 8 10 44
inflammatory disorder of breast 8
inflammatory breast disease nos 8
inflammatory disease of breast 8
inflammatory breast disease 8
breast inflammation nos 8
infectious mastitis 60
mastitis nos 8


External Ids:

Disease Ontology8 DOID:10690
MeSH34 D008413
NCIt39 C53662
ICD9CM27 611.0
ICD1025 N61

Related Diseases for Mastitis

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Sources:
17GeneCards, 18GeneDecks
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Diseases related to Mastitis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 75)
idRelated DiseaseScoreTop Affiliating Genes
1pneumonia30.2VTN, LACTB
2toxic shock syndrome30.0SELM, SELK, SELO, LACTB
3systemic lupus erythematosus30.0VTN, NOD2, LTF, CSN1S1
4arthritis30.0VTN, LACTB, NOD2, CXCL6, HP, LTF
5peritonitis29.8LACTB
6diabetes mellitus29.8VTN, GPX5, HP, CSN1S1
7breast cancer10.3
8granulomatous mastitis10.3
9neonatal infective mastitis10.2
10inflammatory breast carcinoma10.2
11tuberculosis10.1
12rhinotracheitis10.0
13calciphylaxis10.0
14breast lymphoma10.0
15breast disease10.0
16lupus erythematosus10.0
17protein-energy malnutrition10.0CSN1S1
18dysentery10.0LTF, LACTB
19periodontal disease10.0LTF
20staphyloenterotoxemia10.0SELO, SELK, SELM
21lactose intolerance10.0LTF, CSN1S1
22liver cirrhosis10.0VTN, LACTB, LTF, CSN1S1
23sepsis10.0LTF, CXCL6, NOD2, LACTB, VTN
24dental caries10.0CSN1S1, LPO, LTF
25cystic fibrosis10.0LPO, LTF, HP, LACTB
26perinatal necrotizing enterocolitis10.0LTF
27chronic kidney failure10.0VTN, LACTB, HP, LTF
28celiac disease10.0LALBA, CSN1S1
29asthma10.0VTN, NOD2, CXCL6, LPO, CSN1S1
30adenocarcinoma10.0CSN1S1, VTN
31reactive arthritis10.0LTF, HP
32glomerulonephritis10.0VTN, CSN1S1
33atopic dermatitis10.0LALBA, NOD2, CSN1S1
34membranous glomerulonephritis10.0HP, VTN
35crohn's disease10.0NOD2, LTF
36breast reconstruction9.9
37prolactinoma9.9
38ductal carcinoma in situ9.9
39relapsing polychondritis9.9
40male breast cancer9.9
41granulomatous dermatitis9.9
42cat-scratch disease9.9
43hepatitis e9.9
44hyperprolactinemia9.9
45sweat gland carcinoma9.9
46wegener's granulomatosis9.9
47pasteurellosis9.9
48leukocyte adhesion deficiency9.9
49hidradenitis suppurativa9.9
50breast apocrine carcinoma9.9

Graphical network of the top 20 diseases related to Mastitis:



Diseases related to mastitis

Clinical Features for Mastitis

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Drugs & Therapeutics for Mastitis

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
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Approved drugs:

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Drug clinical trials:

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Search NIH Clinical Center for Mastitis

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Genetic Tests for Mastitis

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Anatomical Context for Mastitis

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32MalaCards
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MalaCards organs/tissues related to Mastitis:

32
Breast, Testes, Liver, Pituitary

Animal Models for Mastitis or affiliated genes

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Publications for Mastitis

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Sources:
50PubMed
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Articles related to Mastitis:

(show top 50)    (show all 692)
idTitleAuthorsYear
1
Lack of efficacy of homeopathic therapy against post-calving clinical mastitis in dairy herds in the Waikato region of New Zealand. (23701404)
2014
2
Feasibility of utilising an infrared-thermographic technique for early detection of subclinical mastitis in dairy camels (Camelus dromedarius). (24331516)
2014
3
Trematode infections in pregnant ewes can predispose to mastitis during the subsequent lactation period. (24331730)
2013
4
Breast ductal carcinoma in situ presenting as recurrent non-puerperal mastitis: case report and literature review. (23924035)
2013
5
Dynamics of milk leukocytes in response to a biological response modifier during bovine subclinical mastitis. (23867121)
2013
6
Antimicrobial resistance and molecular epidemiology of streptococci from bovine mastitis. (22964008)
2013
7
Evaluation of a LPS-based glycoconjugate vaccine against bovine Escherichia coli mastitis: Formation of LPS Abs in cows after immunization with E. coli core oligosaccharides conjugated to hemocyanine. (23112009)
2013
8
Management of idiopathic granulomatous mastitis diagnosed by core biopsy: a retrospective multicenter study. (23663101)
2013
9
Lupus mastitis: a review. (23190681)
2013
10
Characterisation of Pseudomonas aeruginosa related to bovine mastitis. (24334080)
2013
11
Comparison of methods for the detection of biofilm formation by Staphylococcus aureus isolated from bovine subclinical mastitis. (24159293)
2013
12
Molecular identification and antimicrobial susceptibility of Nocardia spp. isolated from bovine mastitis in Brazil. (24060098)
2013
13
Idiopathic granulomatous mastitis: A rare entity with a variable presentation. (24225266)
2013
14
Male tuberculous mastitis: a rare entity. (24045526)
2013
15
Bayesian estimation of test characteristics of real-time PCR, bacteriological culture and California mastitis test for diagnosis of intramammary infections with Staphylococcus aureus in dairy cattle at routine milk recordings. (23992955)
2013
16
Short communication: differential immunoglobulin transfer during mastitis challenge by pathogen-specific components. (23295119)
2013
17
Short communication: experimentally induced mastitis reduces weight shifting between the rear legs while standing in dairy cows. (23497993)
2013
18
Effects of Jin-Ying-Tang on Staphylococcus aureus-induced mastitis in rabbit. (22303901)
2012
19
Genotypic characterization and evaluation of an antibiotic resistance of Trueperella pyogenes (Arcanobacterium pyogenes) isolated from milk of dairy cows with clinical mastitis. (22868181)
2012
20
Minimum inhibitory concentrations of Staphylococcus aureus recovered from clinical and subclinical cases of bovine mastitis. (22459838)
2012
21
Molecular diagnostics applied to mastitis problems on dairy farms. (23101676)
2012
22
Association of BoLA-DRB3 alleles with mastitis resistance and susceptibility in Japanese Holstein cows. (22574787)
2012
23
Medical and surgical treatment of idiopathic granulomatous lobular mastitis: a benign inflammatory disease mimicking invasive carcinoma. (22493638)
2012
24
Technical note: Development of a challenge model for Streptococcus uberis mastitis in dairy heifers. (23040028)
2012
25
Quarter-milking-, quarter-, udder- and lactation-level risk factors and indicators for clinical mastitis during lactation in pasture-fed dairy cows managed in an automatic milking system. (22510075)
2012
26
MRI findings of inflammatory breast cancer, locally advanced breast cancer, and acute mastitis: T2-weighted images can increase the specificity of inflammatory breast cancer. (22351245)
2012
27
Staphylococcus aureus proteins differentially recognized by the ovine immune response in mastitis or nasal carriage. (22342493)
2012
28
Idiopathic granulomatous mastitis: a report of twenty cases. (22677299)
2012
29
Genome analysis of bovine-mastitis-associated Escherichia coli O32:H37 strain P4. (22740662)
2012
30
Multicentre Etest evaluation of in vitro activity of conventional antifungal drugs against European bovine mastitis Prototheca spp. isolates. (22523316)
2012
31
A mathematical model to study resistance and tolerance to infection at the animal and population levels: application to E. coli mastitis. (23248637)
2012
32
Update on control of Staphylococcus aureus and Streptococcus agalactiae for management of mastitis. (22664203)
2012
33
Molecular epidemiology of Mannheimia haemolytica and Mannheimia glucosida associated with ovine mastitis. (22621951)
2012
34
Mycotic mastitis in three dogs due to Blastomyces dermatitidis. (21852517)
2011
35
Escherichia coli from clinical mastitis: serotypes and virulence factors. (22362795)
2011
36
Deterministic model to evaluate the impact of lactational treatment of subclinical mastitis due to coagulase-negative staphylococci. (21774857)
2011
37
Granulomatous mastitis: presentation, treatment and outcome in 43 patients. (20569938)
2010
38
Cutaneous actinomycosis presenting as chronic mastitis. (19438536)
2010
39
Bilateral primary breast lymphoma masquerading as lactating mastitis. (20728042)
2010
40
Idiopathic granulomatous mastitis. (19139772)
2009
41
Idiopathic granulomatous mastitis: a heterogeneous disease with variable clinical presentation. (17541683)
2007
42
Chronic idiopathic granulomatous mastitis. (17894025)
2007
43
Idiopathic granulomatous mastitis in the male breast. (15647084)
2005
44
Delayed neutrophil apoptosis in bovine subclinical mastitis. (15545372)
2004
45
The magnetic resonance image findings of idiopathic granulomatous mastitis. (15573210)
2004
46
Clinical characteristics, prevalence, influence on sow performance, and assessment of sow-related risk factors for granulomatous mastitis in sows. (12693537)
2003
47
Lactoperoxidase activity and thiocyanate content of milk from cows with mastitis in different lactation stages]. (7646426)
1995
48
Isolation and characterization of alpha 2-macroglobulin from mastitis milk. (1383300)
1992
49
Granulomatous mastitis. (2488557)
1989
50
Granulomatous mastitis: a report of seven cases. (6889612)
1982

Genetic Variations for Mastitis

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Expression for genes affiliated with Mastitis

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Mastitis

Search GEO for disease gene expression data for Mastitis.

Pathways for genes affiliated with Mastitis

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37NCBI BioSystems Database
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Pathways related to Mastitis according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
110.3SELM, SELK, SELO
210.3SELM, SELK, SELO

Compounds for genes affiliated with Mastitis

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Sources:
44Novoseek, 24HMDB, 11DrugBank, 28IUPHAR, 59Tocris Bioscience, 49PharmGKB, 2BitterDB
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Compounds related to Mastitis according to GeneCards/GeneDecks:

(show all 43)
idCompoundScoreTop Affiliating Genes
1exorphins4410.8CSN1S1, LTF
2cmpa4410.8CSN1S1, LALBA
3thiocyanate44 2411.8LPO, LTF, TST
4cyanide44 2411.8TST, HP, LPO
5lactose44 1111.8LALBA, HP, LTF, CSN1S1
6polyacrylic acid4410.8CSN1S1, VTN
7rifampicin44 28 5912.8LACTB, HP, LTF
8polyethylene glycol4410.8CSN1S1, HP, LALBA, VTN
9aspartate4410.8NDUFAB1, CSN1S1, LTF, VTN
10sodium dodecylsulfate4410.8VTN, LALBA, HP, CSN1S1
11whey4410.8LALBA, LTF, LPO, CSN1S1
12kininogen4410.7CSN1S1, HP, VTN
13urea44 11 2412.7CSN1S1, HP, LALBA, VTN
14sialic acid4410.7VTN, HP, LTF, LPO
15carbohydrates4410.7LALBA, HP, LTF, CSN1S1
16vitamin b124410.7CSN1S1, LTF, HP
17polysaccharide4410.7VTN, LALBA, HP, LTF, CSN1S1
18nacl4410.7CSN1S1, LTF, HP, LALBA
19fibrinogen4410.7CSN1S1, LTF, HP, LALBA, VTN
20selenium44 2411.7SELM, SELK, GPX5, LPO
21hypothiocyanite44 2411.7LTF, LPO
22lactulose4410.7LTF, NOD2
23ovomucoid4410.7CSN1S1, LALBA
24succinate4410.7LTF, CSN1S1, NDUFAB1
25polyacrylamide4410.7LALBA, HP, LTF, CSN1S1
26sodium chlorate4410.7LTF, VTN
27iron44 2411.7NDUFAB1, LPO, LTF, HP, LALBA, TST
28lactate4410.7NDUFAB1, CSN1S1, LPO, HP, VTN
29phenolphthalein44 1111.7LPO, LTF
30heparin44 28 11 2413.7CSN1S1, LTF, HP, LALBA, VTN
31ascorbic acid44 2411.6HP, LTF, LPO, CSN1S1
32alanine4410.6VTN, LALBA, HP, LTF, CSN1S1, NDUFAB1
33aprotinin44 1111.6LALBA, LTF, CSN1S1
34trichloroacetic acid4410.6LALBA, CSN1S1
35ampicillin44 1111.6LTF, LACTB
36methionine4410.5CSN1S1, LPO, HP, LALBA
37amoxicillin44 49 1112.5LACTB, LTF
38cysteine4410.4CSN1S1, LPO, LTF, HP, LALBA, VTN
39gliadin4410.4LALBA, CSN1S1
40mannitol44 1111.4LALBA, NOD2, CSN1S1
41serine4410.3CSN1S1, LTF, HP, CXCL6, NOD2, LACTB
42ofloxacin44 2 1112.3LTF, LACTB
43metronidazole44 1111.1LTF, LACTB

GO Terms for genes affiliated with Mastitis

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16Gene Ontology
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Biological processes related to Mastitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1response to oxidative stressGO:00697910.3SELK, GPX5, LPO
2defense response to bacteriumGO:04274210.1LALBA, NOD2, HP, LTF

Molecular functions related to Mastitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1heparin bindingGO:00820110.4VTN, CXCL6, LTF

Products for genes affiliated with Mastitis

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Mastitis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet