MCID: MST005
MIFTS: 51

Mastitis malady

Categories: Reproductive diseases, Endocrine diseases

Aliases & Classifications for Mastitis

Aliases & Descriptions for Mastitis:

Name: Mastitis 12 52 42 14 69
Inflammation of Non-Human Mammary Gland 69
Inflammatory Disorder of Breast 69
Inflammatory Disease of Breast 12
Inflammatory Breast Disease 12
Breast Inflammation 12

Classifications:



External Ids:

Disease Ontology 12 DOID:10690
MeSH 42 D008413
NCIt 47 C53662
ICD10 33 N61
UMLS 69 C0024894

Summaries for Mastitis

MalaCards based summary : Mastitis, also known as inflammation of non-human mammary gland, is related to granulomatous mastitis and granulomatous lobular mastitis, and has symptoms including signs and symptoms in breast An important gene associated with Mastitis is LTF (Lactotransferrin), and among its related pathways/superpathways are Innate Immune System and Toll-Like receptor Signaling Pathways. The drugs Hydrocortisone and Histamine have been mentioned in the context of this disorder. Affiliated tissues include breast, testes and neutrophil, and related phenotypes are Decreased viability and hematopoietic system

Wikipedia : 71 Mastitis (also called mammitis) is inflammation of breast or udder tissue usually due to infection.... more...

Related Diseases for Mastitis

Diseases related to Mastitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 170)
id Related Disease Score Top Affiliating Genes
1 granulomatous mastitis 12.3
2 granulomatous lobular mastitis 12.2
3 neonatal infective mastitis 11.9
4 eosinophilic mastitis 11.9
5 breast abscess 11.2
6 inflammatory breast carcinoma 11.1
7 diabetic mastopathy 11.1
8 myeloid proliferations related to down syndrome 10.3 CXCL8 TLR2
9 coronary arterial fistulas 10.3 CXCL8 LTF NOD2
10 handl syndrome 10.3 CXCL8 LTF TLR2
11 psychotic disorder 10.3 CXCL8 IL6 LTF
12 retinal vascular disease 10.3 CXCL8 IL6 LTF
13 vps11-related autosomal recessive hypomyelinating leukodystrophy 10.3 CCL5 IL6
14 bullous retinoschisis 10.2 CXCL8 IL6 SLPI
15 parkinson disease 11 10.2 CXCL8 IL17A NOD2
16 mikulicz disease 10.2 ALB IL6 LTF
17 labyrinthine bilateral reactive loss 10.2 ALB CXCL8 IL6
18 inappropriate adh syndrome 10.2 CXCL8 IL6 TLR2
19 fallopian tube serous adenocarcinoma 10.2 ALB CXCL8 IL6
20 neurological manifestations of pompe disease 10.2 ALB CP
21 stenosis of lacrimal sac 10.2 CXCL8 IL6 LTF
22 atrophy of prostate 10.2 CXCL8 IL6 TLR2
23 autoimmune disease of central nervous system 10.2 IL6 LBP TLR2
24 oculomotor nerve paralysis 10.2 CXCL8 IL6
25 allergic bronchopulmonary aspergillosis 10.2 ALB CXCL8 IL6
26 adnp syndrome 10.2 CXCL8 IL6 LBP
27 erb-duchenne and dejerine-klumpke palsies 10.2 CCL5 CXCL8 IL6
28 mixed mineral dust pneumoconiosis 10.2 CCL5 CXCL8 IL6
29 trichomalacia 10.2 CXCL8 IL17A IL6
30 reproductive system disease 10.2 IL17A IL6 TLR2
31 gastric dilatation 10.2 CXCL8 IL17A IL6
32 depressed scar 10.2 ALB CXCL8 IL6
33 unilateral hypoactive labyrinth 10.2 ALB CXCL8 TLR2
34 patellar tendinitis 10.2 ALB CCL5 CXCL8
35 paranasal sinus sarcoma 10.2 ALB CXCL8 IL6
36 nasal cavity inverting papilloma 10.2 CCL5 CP CXCL8
37 epidermolysis bullosa dystrophica, ad 10.2 BPI LBP TLR2
38 disease of mental health 10.2 IL17A IL6 TLR2
39 early yaws 10.2 ALB CCL5 IL6
40 nguyen syndrome 10.2 IL17A TLR2
41 familial renal papillary carcinoma 10.2 ALB CXCL8 SLPI
42 colon adenocarcinoma 10.2 ALB CXCL8 IL6
43 burns 10.2 CXCL8 IL17A IL6
44 smooth muscle tumor 10.2 CCL5 IL17A IL6
45 keratomalacia 10.2 CXCL8 IL6 TLR2
46 premature menopause 10.2 IL6 LBP NOD2 TLR2
47 non-gestational choriocarcinoma 10.2 ALB CCL5 IL17A
48 bladder sarcoma 10.2 ALB CP IL6
49 uterine adnexa cancer 10.2 IL17A IL6 TLR2
50 spastic entropion 10.1 ALB HP LTF

Comorbidity relations with Mastitis via Phenotypic Disease Network (PDN):


Acute Cystitis Fat Necrosis of Breast
Female Breast Cancer Hypertension, Essential
Microglandular Adenosis

Graphical network of the top 20 diseases related to Mastitis:



Diseases related to Mastitis

Symptoms & Phenotypes for Mastitis

UMLS symptoms related to Mastitis:


signs and symptoms in breast

GenomeRNAi Phenotypes related to Mastitis according to GeneCards Suite gene sharing:

26
id Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased viability GR00240-S-1 9.17 LBP
2 Decreased viability GR00381-A-1 9.17 LTF CSN3 LBP
3 Decreased viability GR00381-A-3 9.17 LTF CSN3 LBP

MGI Mouse Phenotypes related to Mastitis:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 10 IL17A IL6 LBP LTF NOD2 SLPI
2 homeostasis/metabolism MP:0005376 9.93 HP IL17A IL6 LBP LTF NOD2
3 immune system MP:0005387 9.7 CCL5 CP CXCL6 HP IL17A IL6
4 liver/biliary system MP:0005370 9.17 ALB CP HP IL6 LBP LTF

Drugs & Therapeutics for Mastitis

Drugs for Mastitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 95)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Hydrocortisone Approved, Vet_approved Phase 4 50-23-7 5754 657311
2
Histamine Approved, Investigational Phase 4 75614-87-8, 51-45-6 774
3
Butyric Acid Experimental Phase 4 107-92-6 264
4 Cortisol succinate Phase 4
5 Hydrocortisone 17-butyrate 21-propionate Phase 4
6 Hydrocortisone acetate Phase 4
7
Histamine Phosphate Phase 4 51-74-1 65513
8 Neurotransmitter Agents Phase 4
9 Histamine Antagonists Phase 4
10 Dermatologic Agents Phase 4
11 Hydrocortisone-17-butyrate Phase 4
12 Anti-Inflammatory Agents Phase 4
13
Selenium Approved, Vet_approved Phase 3 7782-49-2
14
Amoxicillin Approved, Vet_approved Phase 2, Phase 3 26787-78-0 33613 2171
15
Cloxacillin Approved, Vet_approved Phase 2, Phase 3 61-72-3 6098
16
Hydroxocobalamin Approved Phase 3 13422-51-0 11953898 5460373 44475014
17
Pyridoxine Approved, Nutraceutical, Vet_approved Phase 3 65-23-6 1054
18
Niacin Approved, Investigational, Nutraceutical Phase 3 59-67-6 938
19
Vitamin A Approved, Nutraceutical, Vet_approved Phase 3 11103-57-4, 68-26-8 445354
20
leucovorin Approved, Nutraceutical Phase 3 58-05-9 54575, 6560146 143
21
Riboflavin Approved, Nutraceutical, Vet_approved Phase 3 83-88-5 493570
22
Vitamin C Approved, Nutraceutical Phase 3 50-81-7 5785 54670067
23
Nicotinamide Approved, Nutraceutical Phase 3 98-92-0 936
24
Thiamine Approved, Nutraceutical, Vet_approved Phase 3 59-43-8 1130
25
Pyridoxal Approved, Nutraceutical Phase 3 66-72-8 1050
26
Folic Acid Approved, Nutraceutical, Vet_approved Phase 3 59-30-3 6037
27
Cyanocobalamin Approved, Nutraceutical Phase 3 68-19-9 44176380
28
Vitamin E Approved, Nutraceutical, Vet_approved Phase 3,Phase 2 59-02-9 14985
29 Clavulanic Acid Phase 2, Phase 3
30 Nicotinic Acids Phase 3
31 Tocopherols Phase 3,Phase 2
32 Tocotrienols Phase 3,Phase 2
33 Trace Elements Phase 3,Phase 2
34 Vitamin B 12 Phase 3
35 Vitamin B 6 Phase 3
36 Vitamin B Complex Phase 3
37 Anti-Bacterial Agents Phase 2, Phase 3
38 Vitamins Phase 3,Phase 2
39 beta-Lactamase Inhibitors Phase 2, Phase 3
40 beta-Lactams Phase 2, Phase 3
41 Anti-Infective Agents Phase 2, Phase 3
42 Protective Agents Phase 3,Phase 2
43 Lactams Phase 2, Phase 3
44 Antibiotics, Antitubercular Phase 2, Phase 3
45 Retinol palmitate Phase 3
46 Micronutrients Phase 3,Phase 2
47 Antitubercular Agents Phase 2, Phase 3
48 Antioxidants Phase 3,Phase 2
49 Carotenoids Phase 3
50 Acidophilus Nutraceutical Phase 2, Phase 3,Phase 1

Interventional clinical trials:

(show all 18)
id Name Status NCT ID Phase
1 Medical and Surgical Treatment for Idiopathic Granulomatous Mastitis Recruiting NCT02959580 Phase 4
2 Use of Probiotic Lactobacilli for the Treatment of Lactational Mastitis Completed NCT00716183 Phase 2, Phase 3
3 Partnership on Nutrition and HIV/AIDS Research in Tanzania: Exploratory Research Study on Selenium and HIV Infection Completed NCT00197561 Phase 3
4 Vitamins, Breastmilk HIV Shedding, and Child Health Completed NCT00197756 Phase 3
5 Study of a Probiotic Strain to Prevent Mastitis and to Eradicate GBS Colonization Unknown status NCT01505361 Phase 1, Phase 2
6 The Use of Pentoxifylline and Vitamin E in the Treatment of Chronic Breast Pain Terminated NCT00188669 Phase 2
7 Survey of Optical Values of the Breast Using Radiation-Free Pressure-Free Optical Scanning Unknown status NCT00671385
8 Evaluation of Lactobacillus Fermentum CECT5716 on the Incidence of Mastitis Completed NCT02203877
9 Staphylococcus Aureus Carrier Status in Breastfeeding Mothers and Infants and the Risk of Lactation Mastitis Completed NCT00620984
10 Global Effects of a Probiotic Strain on Lactating Women Completed NCT01124448
11 Study of Acupuncture and Care Interventions for the Treatment of Breast Inflammation During Breastfeeding Completed NCT00405158
12 Nursing Education Intervention for Maternal Breastfeeding Completed NCT02106026
13 Painful Breastfeeding and Bacterial or Yeast Infection Completed NCT01631461
14 L.Fermentum CECT5716 in Treatment of Breast Pain Completed NCT02093338
15 Study of Effectiveness and Safety of Azithromycin-based Extended-spectrum Prophylaxis to Prevent Post Cesarean Infection Completed NCT01235546
16 Impact of Maternal Stress on Infant Stunting Completed NCT02755012
17 Ductal Lavage in Non-lactating Female Women With Mastitis Active, not recruiting NCT02794688
18 Granulomatous Mastitis Current Approach and Treatment Enrolling by invitation NCT02667132

Search NIH Clinical Center for Mastitis

Cochrane evidence based reviews: mastitis

Genetic Tests for Mastitis

Anatomical Context for Mastitis

MalaCards organs/tissues related to Mastitis:

39
Breast, Testes, Neutrophil, Pituitary, Bone, Liver

Publications for Mastitis

Articles related to Mastitis:

(show top 50) (show all 905)
id Title Authors Year
1
Biofilm production and beta-lactamic resistance in Brazilian Staphylococcus aureus isolates from bovine mastitis. ( 27913076 )
2017
2
Whole-Genome Sequence of Streptococcus parauberis Strain SP-llh, Isolated from Cows with Mastitis in Western China. ( 28082485 )
2017
3
Pituitary Adenoma and Hyperprolactinemia Accompanied by Idiopathic Granulomatous Mastitis. ( 28321344 )
2017
4
Rifampicin for Idiopathic Granulomatous Lobular Mastitis: A Promising Alternative for Treatment. ( 28050664 )
2017
5
Selective, reliable blood and milk bio-markers for diagnosing clinical and subclinical bovine mastitis. ( 27915437 )
2017
6
Draft Genome Sequence of Staphylococcus aureus 1608, a Strain That Caused Toxic Mastitis in Twin Cows. ( 28057751 )
2017
7
Differential diagnosis of idiopathic granulomatous mastitis and breast cancer using acoustic radiation force impulse imaging. ( 27787642 )
2017
8
Risperidone Induced Granulomatous Mastitis Secondary to Hyperprolactinemia in a Non-Pregnant Woman-A Rare Case Report in a Bipolar Disorder. ( 28273980 )
2017
9
Biofilm formation and antimicrobial resistance genes of coagulase-negative staphylococci isolated from cows with mastitis in Argentina. ( 28087612 )
2017
10
In Vitro Assessment of the Probiotic Potential of Lactococcus lactis LMG 7930 against Ruminant Mastitis-Causing Pathogens. ( 28068371 )
2017
11
Mangiferin inhibits mastitis induced by LPS via suppressing NF-A,B and NLRP3 signaling pathways. ( 27984712 )
2017
12
The Brief Case: Recurrent Granulomatous Mastitis Due to Corynebacterium kroppenstedtii. ( 27458268 )
2016
13
Idiopathic granulomatous mastitis mimicking inflammatory breast carcinoma: What are the odds? ( 27790396 )
2016
14
Mastitis Modifies the Biogenic Amines Profile in Human Milk, with Significant Changes in the Presence of Histamine, Putrescine and Spermine. ( 27584695 )
2016
15
Chronic Mastitis in Egypt and Morocco: Differentiating between Idiopathic Granulomatous Mastitis and IgG4-Related Disease. ( 27279578 )
2016
16
Evaluation of therapeutic mammoplasty techniques in the surgical management of female patients with idiopathic granulomatous mastitis with mild to moderate inflammatory symptoms in terms of recurrence and patients' satisfaction. ( 27177342 )
2016
17
Incidence of mastitis and activity of milk neutrophils in Tharparkar cows reared under semi-arid conditions. ( 27154217 )
2016
18
Idiopath=ic Granulomatous Lobular Mastitis Masquerading as a Breast Tumor: A Case Report. ( 27437133 )
2016
19
Closing the Brief Case: Recurrent Granulomatous Mastitis Due to Corynebacterium kroppenstedtii. ( 27458276 )
2016
20
Granulomatous Mastitis: A Rare Cause of Male Breast Lump. ( 27721777 )
2016
21
Estimation of Mineral and Trace Element Profile in Bubaline Milk Affected with Subclinical Mastitis. ( 27631328 )
2016
22
Idiopathic Granulomatous Mastitis: Cytologic and Histologic Study of 65 Egyptian Patients. ( 27607182 )
2016
23
Single nucleotide polymorphisms in the CXCR1 gene and its association with clinical mastitis incidence in Polish Holstein-Friesian cows. ( 27173275 )
2016
24
Detection of plasmid-borne extended-spectrum I^-lactamase (ESBL) genes in Escherichia coli isolates from bovine mastitis. ( 27566885 )
2016
25
Reply to "Granulomatous Mastitis - More data is needed". ( 26832944 )
2016
26
Granulomatous Mastitis: Time to Introduce New Weapons. ( 26920409 )
2016
27
A variety of gene polymorphisms associated with idiopathic granulomatous mastitis. ( 27619324 )
2016
28
Recurrent periductal mastitis: Surgical treatment. ( 27616631 )
2016
29
Correction: Deciphering Transcriptome and Complex Alternative Splicing Transcripts in Mammary Gland Tissues from Cows Naturally Infected with Staphylococcus aureus Mastitis. ( 27907216 )
2016
30
A case of non-lacrimal immunoglobulin G4 (IgG4)-related orbital disease with mastitis. ( 26700191 )
2016
31
Effect of mastitis on luteal function and pregnancy rates in buffaloes. ( 27177967 )
2016
32
Mastitis associated with SjAPgren's syndrome: a series of nine cases. ( 27561784 )
2016
33
Comparison of Virulence Gene Identification, Ribosomal Spacer PCR, and Pulsed Field Gel Electrophoresis for Strain-Typing Staphylococcus aureus Isolated from Cases of Subclinical Bovine Mastitis in the USA. ( 27194685 )
2016
34
Polymorphism in spa gene of Staphylococcus aureus from bovine subclinical mastitis. ( 27182140 )
2016
35
Xanthogranulomatous Mastitis Mimicking Locally Advanced Breast Cancer. ( 27900804 )
2016
36
Imaging Findings in Patients with Granulomatous Mastitis. ( 27853497 )
2016
37
Idiopathic granulomatous mastitis: imaging update and review. ( 27221974 )
2016
38
Idiopathic granulomatous mastitis: Long-discussed but yet-to-be-known. ( 26829298 )
2016
39
Prevalence of Bovine Mastitis Pathogens in Bulk Tank Milk in China. ( 27187065 )
2016
40
N-acetyl -I^-D-glucosaminidase activity in cow milk as an indicator of mastitis. ( 27210494 )
2016
41
Change in viable bacterial count during preservation of milk derived from dairy cows with subclinical mastitis and its relationship with antimicrobial components in milk. ( 27109069 )
2016
42
Supraphysiological oxytocin increases the transfer of immunoglobulins and other blood components to milk during lipopolysaccharide- and lipoteichoic acid-induced mastitis in dairy cows. ( 27592421 )
2016
43
In Vivo Pharmacokinetics/Pharmacodynamics of Cefquinome in an Experimental Mouse Model of Staphylococcus Aureus Mastitis following Intramammary Infusion. ( 27218674 )
2016
44
Nonpuerperal Mastitis Acts as the Initial Presentation of Pituitary Prolactinoma. ( 27508332 )
2016
45
Idiopathic granulomatous mastitis: a diagnostic dilemma for the breast radiologist. ( 27164916 )
2016
46
Bovine mastitis: prevalence, risk factors and isolation of Staphylococcus aureus in dairy herds at Hawassa milk shed, South Ethiopia. ( 27912754 )
2016
47
Short communication: In vivo screening platform for bacteriocins using Caenorhabditis elegans to control mastitis-causing pathogens. ( 27638256 )
2016
48
The Role of Interleukin-33 as an Inflammatory Marker in Differential Diagnosis of Idiopathic Granulomatous Mastitis and Breast Cancer. ( 27780363 )
2016
49
ESBL-Producing Escherichia coli from Cows Suffering Mastitis in China Contain Clinical Class 1 Integrons with CTX-M Linked to ISCR1. ( 27965653 )
2016
50
Antibiotic safety considerations in methicillin-resistant Staphylococcus aureus postpartum mastitis. ( 27646759 )
2016

Variations for Mastitis

Expression for Mastitis

Search GEO for disease gene expression data for Mastitis.

Pathways for Mastitis

Pathways related to Mastitis according to GeneCards Suite gene sharing:

(show all 20)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
13.9 BPI CCL5 CXCL8 HP IL17A IL6
2
Show member pathways
12.81 CCL5 CP CXCL8 IL6 NOD2 TLR2
3 12.01 IL6 LBP NOD2 TLR2
4
Show member pathways
11.99 CXCL6 CXCL8 IL17A IL6 TLR2
5
Show member pathways
11.95 CXCL8 IL6 LBP TLR2
6
Show member pathways
11.8 IL17A IL6 TLR2
7
Show member pathways
11.77 IL17A IL6 TLR2
8 11.73 CXCL8 IL6 TLR2
9 11.68 CXCL8 IL17A IL6 LBP
10
Show member pathways
11.67 A2M IL6 LBP
11 11.66 CXCL8 IL6 LBP
12 11.63 CSN2 CXCL8 IL6
13 11.58 CXCL6 CXCL8 IL6
14 11.49 CCL5 CXCL8 IL6
15 11.39 CXCL8 IL6 TLR2
16
Show member pathways
11.32 CXCL6 CXCL8 IL17A IL6 LBP
17 11.27 CCL5 CXCL8 IL6
18 11.23 CXCL8 IL6 TLR2
19 11.05 CCL5 CXCL6 CXCL8 IL17A IL6 TLR2
20 10.78 CCL5 CXCL6 CXCL8 IL17A IL6

GO Terms for Mastitis

Cellular components related to Mastitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.89 A2M ALB BPI CCL5 CP CSN2
2 blood microparticle GO:0072562 9.56 A2M ALB CP HP
3 extracellular space GO:0005615 9.55 A2M ALB BPI CCL5 CP CSN2
4 specific granule lumen GO:0035580 9.46 BPI HP LTF SLPI

Biological processes related to Mastitis according to GeneCards Suite gene sharing:

(show all 34)
id Name GO ID Score Top Affiliating Genes
1 cellular protein metabolic process GO:0044267 9.93 ALB CP IL6 LTF
2 inflammatory response GO:0006954 9.93 CCL5 CXCL6 CXCL8 IL17A IL6 TLR2
3 defense response GO:0006952 9.87 CXCL6 CXCL8 HP NOD2
4 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.86 IL6 LTF NOD2 TLR2
5 cellular response to lipopolysaccharide GO:0071222 9.84 CXCL6 CXCL8 IL6 LBP
6 response to lipopolysaccharide GO:0032496 9.83 CXCL6 IL6 LBP SLPI TLR2
7 chemokine-mediated signaling pathway GO:0070098 9.81 CCL5 CXCL6 CXCL8
8 defense response to Gram-positive bacterium GO:0050830 9.8 IL6 LBP TLR2
9 neutrophil chemotaxis GO:0030593 9.79 CCL5 CXCL6 CXCL8
10 positive regulation of epithelial cell proliferation GO:0050679 9.78 CCL5 IL6 NOD2
11 positive regulation of tumor necrosis factor production GO:0032760 9.77 LBP NOD2 TLR2
12 negative regulation of viral genome replication GO:0045071 9.76 CCL5 LTF SLPI
13 acute-phase response GO:0006953 9.72 HP IL6 LBP
14 cellular response to interleukin-1 GO:0071347 9.71 CCL5 CXCL8 IL17A IL6
15 lipopolysaccharide-mediated signaling pathway GO:0031663 9.69 CCL5 LBP TLR2
16 positive regulation of neutrophil chemotaxis GO:0090023 9.67 CXCL6 CXCL8 LBP
17 positive regulation of nitric-oxide synthase biosynthetic process GO:0051770 9.66 NOD2 TLR2
18 response to molecule of bacterial origin GO:0002237 9.66 CXCL8 TLR2
19 negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 9.65 CCL5 CXCL8
20 neutrophil mediated immunity GO:0002446 9.65 CXCL6 IL6
21 positive regulation of interleukin-8 production GO:0032757 9.65 LBP NOD2 TLR2
22 positive regulation of toll-like receptor 4 signaling pathway GO:0034145 9.64 LBP LTF
23 positive regulation of cytokine production involved in inflammatory response GO:1900017 9.64 IL17A NOD2
24 cellular response to lipoteichoic acid GO:0071223 9.62 LBP TLR2
25 defense response to Gram-negative bacterium GO:0050829 9.62 BPI IL6 LBP LTF
26 negative regulation of cysteine-type endopeptidase activity GO:2000117 9.59 CSN2 LTF
27 negative regulation of macrophage apoptotic process GO:2000110 9.58 CCL5 NOD2
28 immune response GO:0006955 9.56 BPI CCL5 CXCL6 CXCL8 IL17A IL6
29 positive regulation of chemokine production GO:0032722 9.54 IL6 LBP TLR2
30 cytokine secretion involved in immune response GO:0002374 9.52 NOD2 TLR2
31 positive regulation of interleukin-6 production GO:0032755 9.46 IL6 LBP NOD2 TLR2
32 neutrophil activation GO:0042119 9.43 CCL5 CXCL6 CXCL8
33 defense response to bacterium GO:0042742 9.23 BPI CXCL6 HP LALBA LBP LTF
34 neutrophil degranulation GO:0043312 10.05 BPI HP LTF SLPI TLR2

Molecular functions related to Mastitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.35 CCL5 CXCL6 CXCL8 IL17A IL6
2 chemokine activity GO:0008009 9.33 CCL5 CXCL6 CXCL8
3 peptidoglycan binding GO:0042834 9.32 NOD2 TLR2
4 lipopeptide binding GO:0071723 9.26 LBP TLR2
5 lipopolysaccharide binding GO:0001530 8.92 BPI LBP LTF TLR2

Sources for Mastitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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