MCID: MTR044
MIFTS: 19

Maturity-Onset Diabetes of the Young, Type 10 malady

Genetic diseases, Rare diseases, Endocrine diseases, Liver diseases, Nephrological diseases, Fetal diseases, Neuronal diseases categories
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Summaries for Maturity-Onset Diabetes of the Young, Type 10

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MalaCards based summary: Maturity-Onset Diabetes of the Young, Type 10 is related to permanent neonatal diabetes mellitus and diabetes mellitus, and has symptoms including An important gene associated with Maturity-Onset Diabetes of the Young, Type 10 is IDDM2 (insulin-dependent diabetes mellitus 2). The compound testosterone have been mentioned in the context of this disorder. Related mouse phenotype no phenotypic analysis.

Description from OMIM:46 613370

Aliases & Classifications for Maturity-Onset Diabetes of the Young, Type 10

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Maturity-Onset Diabetes of the Young, Type 10, Aliases & Descriptions:

Name: Maturity-Onset Diabetes of the Young, Type 10 46 62


Classifications:



Related Diseases for Maturity-Onset Diabetes of the Young, Type 10

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Symptoms for Maturity-Onset Diabetes of the Young, Type 10

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Symptoms by clinical synopsis from OMIM:

613370

Clinical features from OMIM:

613370

HPO human phenotypes related to Maturity-Onset Diabetes of the Young, Type 10:

id Description Frequency HPO Source Accession
1 autosomal dominant inheritance HP:0000006
2 diabetes mellitus HP:0000819

Drugs & Therapeutics for Maturity-Onset Diabetes of the Young, Type 10

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Drug clinical trials:

Search ClinicalTrials for Maturity-Onset Diabetes of the Young, Type 10

Search NIH Clinical Center for Maturity-Onset Diabetes of the Young, Type 10

Genetic Tests for Maturity-Onset Diabetes of the Young, Type 10

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Anatomical Context for Maturity-Onset Diabetes of the Young, Type 10

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Animal Models for Maturity-Onset Diabetes of the Young, Type 10 or affiliated genes

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MGI Mouse Phenotypes related to Maturity-Onset Diabetes of the Young, Type 10:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00030129.1INS, ZBTB16

Publications for Maturity-Onset Diabetes of the Young, Type 10

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Variations for Maturity-Onset Diabetes of the Young, Type 10

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UniProtKB/Swiss-Prot genetic disease variations for Maturity-Onset Diabetes of the Young, Type 10:

64
id Symbol AA change Variation ID SNP ID
1INSp.Arg6CysVAR_063721rs121908278
2INSp.Arg6HisVAR_063722rs121908259
3INSp.Arg46GlnVAR_063729rs121908260

Clinvar genetic disease variations for Maturity-Onset Diabetes of the Young, Type 10:

6
id Gene Name Type Significance SNP ID Assembly Location
1NM_000207.2(INS): c.16C> T (p.Arg6Cys)single nucleotide variantPathogenicrs121908278GRCh37Chr 11, 2182186: 2182186
2NM_000207.2(INS): c.137G> A (p.Arg46Gln)single nucleotide variantPathogenicrs121908260GRCh37Chr 11, 2182065: 2182065

Expression for genes affiliated with Maturity-Onset Diabetes of the Young, Type 10

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Expression patterns in normal tissues for genes affiliated with Maturity-Onset Diabetes of the Young, Type 10

Search GEO for disease gene expression data for Maturity-Onset Diabetes of the Young, Type 10.

Pathways for genes affiliated with Maturity-Onset Diabetes of the Young, Type 10

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Compounds for genes affiliated with Maturity-Onset Diabetes of the Young, Type 10

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Sources:
44Novoseek, 61Tocris Bioscience, 24HMDB, 11DrugBank
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Compounds related to Maturity-Onset Diabetes of the Young, Type 10 according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1testosterone44 61 24 1112.1INS, ZBTB16

GO Terms for genes affiliated with Maturity-Onset Diabetes of the Young, Type 10

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Molecular functions related to Maturity-Onset Diabetes of the Young, Type 10 according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1identical protein bindingGO:0428029.1INS, ZBTB16

Products for genes affiliated with Maturity-Onset Diabetes of the Young, Type 10

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  • Antibodies
  • Proteins
  • Lysates

Sources for Maturity-Onset Diabetes of the Young, Type 10

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet