MCID: MSL001
MIFTS: 61

Measles malady

Categories: Rare diseases, Infectious diseases

Aliases & Classifications for Measles

Summaries for Measles

MedlinePlus : 41 measles is an infectious disease caused by a virus. it spreads easily from person to person. it causes a blotchy red rash. the rash often starts on the head and moves down the body. other symptoms include fever cough runny nose conjunctivitis (pink eye) feeling achy and run down tiny white spots inside the mouth sometimes measles can lead to serious problems. there is no treatment for measles, but the measles-mumps-rubella (mmr) vaccine can prevent it. "german measles", also known as rubella, is a completely different illness. centers for disease control and prevention

MalaCards based summary : Measles, also known as rubeola, is related to microcephaly and hepatitis c virus, and has symptoms including fever, cough and coryza. An important gene associated with Measles is CD46 (CD46 Molecule), and among its related pathways/superpathways are Innate Immune System and TGF-Beta Pathway. The drugs Vitamin A and Trace Elements have been mentioned in the context of this disorder. Affiliated tissues include eye, brain and skin, and related phenotypes are hematopoietic system and cellular

Disease Ontology : 12 A viral infectious disease that results_in infection located in skin, has material basis in Measles virus, which is transmitted_by contact with oronasal secretions, or semen of an infected person. The infection has symptom fever, has symptom cough, has symptom coryza, has symptom conjunctivitis, and has symptom maculopapular, erythematous rash.

CDC : 3 Measles starts with fever, runny nose, cough, red eyes, and sore throat. It’s followed by a rash that spreads over the body. Measles virus is highly contagious virus and spreads through the air through coughing and sneezing. Make sure you and your child are protected with measles, mumps, and rubella (MMR) vaccine.

Wikipedia : 71 Measles is a highly contagious infection caused by the measles virus. Initial signs and symptoms... more...

Related Diseases for Measles

Diseases related to Measles via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 269)
id Related Disease Score Top Affiliating Genes
1 microcephaly 31.0 IFNG IL2 TLR2
2 hepatitis c virus 29.1 CD209 DDX58 IFIH1 IFNA1 TLR3
3 tuberculosis 28.9 CD40LG IFNB1 IL2 IL4
4 tracheitis 28.9 IFNG IL2 IL4
5 rubella 12.1
6 primary immunodeficiency with post-measles-mumps-rubella vaccine viral infection 11.8
7 panencephalitis, subacute sclerosing 11.7
8 mumps 11.3
9 acute disseminated encephalomyelitis 11.2
10 infections, recurrent, with encephalopathy, hepatic dysfunction, and cardiovasuclar malformations 10.7
11 acute hemorrhagic leukoencephalitis 10.7
12 croup 10.7
13 immune-mediated encephalomyelitis 10.7
14 postinfectious encephalomyelitis 10.7
15 benign exophthalmos syndrome 10.3 IFNA1 IFNB1
16 x-linked intellectual disability, pai type 10.3 DDX58 IFIH1
17 skeletal dysplasias 10.3 DDX58 IFIH1
18 hutchinson incisors 10.2 ADAR IFNG STAT1
19 severe acute respiratory syndrome 10.2 DDX58 IFNA1 IFNB1
20 nephropathy familial with hyperuricemia 10.2 CD46 MSN TLR2
21 xeroderma pigmentosum, group a 10.2 EIF2AK2 IFNA1 STAT1
22 myoglobinuria recurrent 10.2 IFNG IL4
23 anal atresia, hypospadias, and penoscrotal inversion 10.2 CD209 IFNG TLR2
24 vaginal mullerian papilloma 10.2 CD209 CD40LG EIF2AK2
25 methylmalonic aciduria and homocystinuria, cblj type 10.2 IFNA1 IFNB1 STAT1
26 mineral metabolism disease 10.2 CD209 CD40LG DDX58
27 senile cataract 10.2 ADAR DDX58 EIF2AK2 IFNA1
28 osmotic diarrhea 10.1 CD40LG DDX58 IFNB1
29 hereditary alpha tryptasemia syndrome 10.1 CD209 CD40LG IFNG
30 benign deep fibrous histiocytoma 10.1 CD40LG IFNG TLR3
31 hydrophthalmos 10.1 IFNG IL4 TLR3
32 diphtheria 10.1
33 rickettsialpox 10.1 CD40LG IFNG TLR2
34 sexual masochism 10.1 CD209 DDX58 IFNB1 STAT1 TLR3
35 erysipelas 10.1 CD40LG IFNA1
36 congenital rubella 10.1
37 plantar fasciitis 10.1 CD209 CD40LG DDX58 TLR3
38 hyperlucent lung 10.1 CD40LG IFNG TLR2
39 hereditary hemorrhagic telangiectasia 10.1 DDX58 EIF2AK2 IFNA1 IFNAR2
40 disease of mental health 10.0 CD40LG IFNG TLR2
41 tetanus 10.0
42 diabetes mellitus, insulin-dependent, 22 10.0 ADAR DDX58 EIF2AK2 IFIH1 IFNG
43 centronuclear myopathy 5 10.0 CD40LG IFNG IL4
44 inflammatory bowel disease 2 10.0 CD209 IFNG IL4 TLR2
45 oral cavity cancer 10.0 CD40LG IFNG IL4
46 endometrial transitional cell carcinoma 10.0 CD209 IFNG STAT1 TLR2
47 asymptomatic neurosyphilis 10.0 IFNG IL4
48 trachoma 10.0 CD40LG STAT1 TLR3
49 paralytic poliomyelitis 10.0 IFNG IL2 TLR3
50 scarlet fever 10.0

Graphical network of the top 20 diseases related to Measles:



Diseases related to Measles

Symptoms & Phenotypes for Measles

Symptoms:

12
  • fever
  • cough
  • coryza
  • conjunctivitis
  • maculopapular

UMLS symptoms related to Measles:


exanthema, fever, pruritus, koplik spots

MGI Mouse Phenotypes related to Measles:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 10.24 ADAR CD40LG DDX58 EIF2AK2 FCGR2B IFIH1
2 cellular MP:0005384 10.17 ADAR CD40LG DDX58 EIF2AK2 FCGR2B IFIH1
3 homeostasis/metabolism MP:0005376 10.13 ADAR CD40LG DDX58 FCGR2B IFIH1 IFNAR2
4 immune system MP:0005387 10.13 ADAR CD40LG DDX58 EIF2AK2 FCGR2B IFIH1
5 digestive/alimentary MP:0005381 9.95 DDX58 FCGR2B IFNG IL2 IL4 STAT1
6 liver/biliary system MP:0005370 9.81 IFNG IL2 IL4 STAT1 TLR2 ADAR
7 mortality/aging MP:0010768 9.77 STAT1 TLR2 TLR3 ADAR CD40LG DDX58
8 neoplasm MP:0002006 9.28 DDX58 EIF2AK2 IFNAR2 IFNB1 IFNG IL2

Drugs & Therapeutics for Measles

Drugs for Measles (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 104)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Vitamin A Approved, Nutraceutical, Vet_approved Phase 4,Phase 3 11103-57-4, 68-26-8 445354
2 Trace Elements Phase 4,Phase 3
3 Vaccines Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1
4 Vitamins Phase 4,Phase 3
5 Immunoglobulins Phase 4,Phase 3,Phase 2,Phase 1
6 Protective Agents Phase 4,Phase 3
7 Retinol palmitate Phase 4,Phase 3
8 Antibodies Phase 4,Phase 3,Phase 2,Phase 1
9 Micronutrients Phase 4,Phase 3
10 BCG Vaccine Phase 4,Phase 2
11 Antioxidants Phase 4,Phase 3
12 Adjuvants, Immunologic Phase 4
13 Heptavalent Pneumococcal Conjugate Vaccine Phase 4,Phase 3,Phase 2
14 Pharmaceutical Solutions Phase 4,Phase 3,Phase 2,Phase 1
15 Immunoglobulin G Phase 4,Phase 3
16 Immunosuppressive Agents Phase 4,Phase 2,Phase 1
17 Liver Extracts Phase 4,Phase 1
18 retinol Nutraceutical Phase 4,Phase 3
19
Pyrimethamine Approved, Vet_approved Phase 3,Phase 2,Phase 1 58-14-0 4993
20
Sulfadoxine Approved Phase 3,Phase 2,Phase 1 2447-57-6 17134
21
Mefloquine Approved Phase 2, Phase 3 53230-10-7 4046
22
Iron Approved Phase 3 7439-89-6 23925
23
Tetracycline Approved, Vet_approved Phase 3,Phase 2 60-54-8 5353990
24
Amoxicillin Approved, Vet_approved Phase 3 26787-78-0 33613 2171
25
Sulfamethoxazole Approved Phase 3 723-46-6 5329
26
Dapsone Approved, Investigational Phase 2, Phase 3 80-08-0 2955
27
Proguanil Approved Phase 2, Phase 3 500-92-5 4923
28
Trimethoprim Approved, Vet_approved Phase 3 738-70-5 5578
29
Aluminum hydroxide Approved Phase 3,Phase 2,Phase 1 21645-51-2
30
leucovorin Approved, Nutraceutical Phase 3,Phase 2,Phase 1 58-05-9 54575, 6560146 143
31
Folic Acid Approved, Nutraceutical, Vet_approved Phase 3,Phase 2,Phase 1 59-30-3 6037
32 Folic Acid Antagonists Phase 3,Phase 2,Phase 1
33 Vitamin B Complex Phase 3,Phase 2,Phase 1
34 Anti-Infective Agents Phase 3,Phase 2,Phase 1
35 Fanasil, pyrimethamine drug combination Phase 3,Phase 2,Phase 1
36 Antimalarials Phase 3,Phase 2,Phase 1
37 Renal Agents Phase 3,Phase 2,Phase 1
38 Antiparasitic Agents Phase 3,Phase 2,Phase 1
39 Antiprotozoal Agents Phase 3,Phase 2,Phase 1
40
Lactitol Phase 3,Phase 2 585-86-4 3871
41
Chlorproguanil Phase 2, Phase 3 537-21-3 151170 9571037
42 Cytochrome P-450 Enzyme Inhibitors Phase 3
43 PENTA Phase 3,Phase 2
44 Trimethoprim, Sulfamethoxazole Drug Combination Phase 3
45 Anti-Bacterial Agents Phase 3,Phase 2
46 gamma-Globulins Phase 3,Phase 2
47 Immunoglobulins, Intravenous Phase 3,Phase 2
48 Antimetabolites Phase 2, Phase 3
49 Antibiotics, Antitubercular Phase 3,Phase 2
50 Rho(D) Immune Globulin Phase 3,Phase 2

Interventional clinical trials:

(show top 50) (show all 219)
id Name Status NCT ID Phase
1 Additional Measles Vaccine at 4 Months of Age Unknown status NCT01486355 Phase 4
2 Trial of Additional Measles Vaccine to Reduce Child Mortality Unknown status NCT01644721 Phase 4
3 Trial of Additional Measles Vaccine to Reduce Child Mortality. Burkina Faso. Unknown status NCT01668745 Phase 4
4 The Effect on Overall Mortality of a National Policy of Limiting Measles Vaccination to Children Below 12 Months of Age Unknown status NCT01306006 Phase 4
5 The Safety and Immunogenicity Study of Rotavirus Vaccine Simultaneously Vaccinated With MR or MMR Vaccine Unknown status NCT02153866 Phase 4
6 Vitamin A Supplementation With Routine Childhood Vaccines and Mortality and Morbidity Unknown status NCT00168623 Phase 4
7 Vitamin A Supplementation With Bacille Calmette Guerin (BCG) Vaccine Unknown status NCT00168610 Phase 4
8 Early Two-dose Measles Vaccination Trial Completed NCT00168558 Phase 4
9 Long-term Follow-up of Measles Antibodies Completed NCT00168571 Phase 4
10 Coadministration of Measles-rubella and Rotavirus Vaccines Completed NCT01700621 Phase 4
11 Non-Specific Effects of Standard Titre Measles Vaccination Completed NCT00168662 Phase 4
12 Immunogenicity of Co-administration of Measles and Japanese Encephalitis Vaccines Completed NCT02643433 Phase 4
13 Immunogenicity and Safety of Combined Vaccine to Prevent Measles, Mumps, Rubella and Chickenpox Diseases Completed NCT00126997 Phase 4
14 Safety and Efficacy of Measles, Mumps, Rubella Vaccination in Juvenile Idiopathic Arthritis Completed NCT00731965 Phase 4
15 Study on Immunization Schedule of Beijing Tiantan Biological's Measles-mumps-rubella(MMR) Vaccine Completed NCT03160820 Phase 4
16 Comparative Study of the Immunogenicity of MMR (Measles, Mumps and Rubella) Single Dose and Multidose Presentations Completed NCT01777529 Phase 4
17 Immunogenicity and Safety of Hepatitis A Vaccine Given at the Same Time of Measles, Mumps, Rubella Combined Vaccine Completed NCT00313950 Phase 4
18 Measles, Mumps, and Rubella (MMR) Immunity in College Students Completed NCT00962819 Phase 4
19 MMR Vaccination Among HIV-infected Adults Completed NCT02724852 Phase 4
20 Immunology of Non-specific Effects of Vaccine Completed NCT00168545 Phase 4
21 Randomized Study of Not Giving Diphteria-tetanus-pertussis Vaccination With or After Measles Vaccination Completed NCT00244673 Phase 4
22 Hepatitis A Vaccine, Inactivated and Measles, Mumps, Rubella and Varicella Virus Vaccine Live Safety Study (V251-066)(COMPLETED) Completed NCT00326183 Phase 4
23 Assess GSK Biologicals' MMR Vaccine (Priorix) When Given to Healthy Children at the Age of 12 to 18 Months in Singapore. Completed NCT00388440 Phase 4
24 Concomitant Use of Hepatitis A Vaccine With Measles, Mumps, Rubella and Varicella Vaccine and Pneumococcal 7-Valent Conjugate Vaccine in Healthy 12-Month-Old Children (V251-067) Completed NCT00312858 Phase 4
25 IPV Clinical Trial - The Gambia Completed NCT01847872 Phase 4
26 Immune Response to Rotavirus Vaccine After a Supplemental Dose Given at 9 Months of Age With Local EPI Vaccines in Mali Completed NCT02286895 Phase 4
27 Safety Study of a Refrigerator-stable Formulation of VARIVAX® Completed NCT00432731 Phase 4
28 Safety & Immunogenicity of MMR Vaccine by DSJI to That by Needle-Syringe in 15-18 Months Old Children Completed NCT02253407 Phase 4
29 MMR and Varicella Vaccine in Premature Infants Completed NCT00156559 Phase 4
30 Induction of Immunity Against Streptococcus Pneumoniae in Adults With Inflammatory Bowel Disease Completed NCT01908283 Phase 4
31 Different Doses of Vitamin A Supplementation and Male and Female Morbidity and Mortality Completed NCT00168636 Phase 4
32 Study of the Influence of Vaccination in HIV Viral Load and Immunologic Responses Against HIV Completed NCT00329251 Phase 4
33 Efficacy and Safety of Vivaglobin® in Previously Untreated Patients With Primary Immunodeficiency Completed NCT00520494 Phase 4
34 Vitamin A With BCG Vaccine Completed NCT00168597 Phase 4
35 Immunogenicity and Safety of Japanese Encephalitis Vaccine When Given With Measles-Mumps-Rubella Vaccine Recruiting NCT02880865 Phase 4
36 Induction of Immunity Against Measles in Pediatric Liver Transplant Recipients Recruiting NCT01770119 Phase 4
37 Homeopathic Vaccine Trial Recruiting NCT02825368 Phase 4
38 Search for the Measles Vaccine Virus Excretion in Breast Milk of Breastfeeding Women After Postpartum Vaccination With MMR Active, not recruiting NCT02325310 Phase 4
39 Measles-Rubella Vaccine Immunogenicity at 6 and 9 Months of Age Not yet recruiting NCT03071575 Phase 4
40 Responses of Premature Infants to Measles-Mumps-Rubella (MMR) and Varicella Vaccines Terminated NCT00138255 Phase 4
41 Impact of the WHO Recommended Vitamin A Supplementation at Immunisation Contacts Terminated NCT00514891 Phase 4
42 Immunogenicity and Reactogenicity of a Trivalent MMR (Trivivac) in Healthy Infants Unknown status NCT01763268 Phase 2, Phase 3
43 The Community Effectiveness of IPTi in Southern Tanzania Unknown status NCT00152204 Phase 3
44 Immunogenicity and Safety of a Combined Vaccine to Prevent Measles, Mumps, Rubella and Chickenpox Diseases Completed NCT00127010 Phase 3
45 Immunogenicity and Safety of a Combined Vaccine to Prevent Measles, Mumps, Rubella and Chickenpox Diseases Completed NCT00127023 Phase 3
46 Prophylactic Antibiotics in Measles Completed NCT00168532 Phase 3
47 Immunogenicity and Safety of GSK Biologicals' Combined Measles-mumps-rubella Vaccine in Volunteers, Seven Years of Age and Older Completed NCT02058563 Phase 3
48 Determining Long-Term Safety and Efficacy of Japanese Encephalitis Vaccine When Given With Measles Vaccine Completed NCT00412516 Phase 3
49 Study of Japanese Encephalitis Chimeric Virus Vaccine Given With Measles-Mumps-Rubella Vaccine in Taiwanese Toddlers Completed NCT01188343 Phase 3
50 Safety, Tolerability, and Immunogenicity of Measles, Mumps, Rubella, and Varicella (MMRV) Vaccine Made With an Alternative Manufacturing Process (AMP)(V221-027) Completed NCT01536405 Phase 3

Search NIH Clinical Center for Measles

Cochrane evidence based reviews: measles

Genetic Tests for Measles

Anatomical Context for Measles

MalaCards organs/tissues related to Measles:

39
Eye, Brain, Skin, T Cells, Testes, B Cells, Lung

The Foundational Model of Anatomy Ontology organs/tissues related to Measles:

18
Skin

Publications for Measles

Articles related to Measles:

(show top 50) (show all 1381)
id Title Authors Year
1
Does Measles Vaccination Reduce the Risk of Acute Respiratory Infection (ARI) and Diarrhea in Children: A Multi-Country Study? ( 28076428 )
2017
2
Sporadic cases of adult measles: a research article. ( 28069071 )
2017
3
Modulation of the Type I Interferon Response Defines the Sensitivity of Human Melanoma Cells to Oncolytic Measles Virus. ( 28042780 )
2017
4
Community-wide measles outbreak in the Region of Madrid, Spain, 10A years after the implementation of the Elimination Plan, 2011-2012. ( 28059628 )
2017
5
The Conundrum in the Diagnosis and Management of Atypical Fulminant Measles in a Leukemia Survivor on Maintenance Chemotherapy. ( 27992394 )
2017
6
Pancreatic pseudocyst after measles, mumps, and rubella vaccination. ( 28082255 )
2017
7
"Screening Different Host Cell Lines for the Dynamic Production of Measles Virus". ( 28054473 )
2017
8
Decreasing Seroprevalence of Measles Antibodies after Vaccination - Possible Gap in Measles Protection in Adults in the Czech Republic. ( 28085960 )
2017
9
Cost Analysis of Measles in Refugees Arriving at Los Angeles International Airport from Malaysia. ( 28068211 )
2017
10
The end of measles and congenital rubella: an achievable dream? ( 28067934 )
2017
11
Effect of an Early Dose of Measles Vaccine on Morbidity Between 18 Weeks and 9 Months of Age: A Randomized, Controlled Trial in Guinea-Bissau. ( 28077730 )
2017
12
Mumps Outbreak at a University and Recommendation for a Third Dose of Measles-Mumps-Rubella Vaccine - Illinois, 2015-2016. ( 27467572 )
2016
13
Environmental, dietary and case-control study of Nodding Syndrome in Uganda: A post-measles brain disorder triggered by malnutrition? ( 27653888 )
2016
14
Seroprevalences of Specific IgG Antibodies to Measles, Mumps, and Rubella in Korean Infants. ( 27822935 )
2016
15
Global measles and rubella laboratory network support for elimination goals, 2010a892015. ( 27156255 )
2016
16
Predictors of Uptake and Timeliness of Newly Introduced Pneumococcal and Rotavirus Vaccines, and of Measles Vaccine in Rural Malawi: A Population Cohort Study. ( 27152612 )
2016
17
Determinants of European parents' decision on the vaccination of their children against measles, mumps and rubella: A systematic review and meta-analysis. ( 27163657 )
2016
18
Population Dependency of Measles, Syphilis and Amebiasis in Japan and Community Evolution. ( 27795472 )
2016
19
Immunovirotherapy with measles virus strains in combination with anti-PD-1 antibody blockade enhances antitumor activity in glioblastoma treatment. ( 27663389 )
2016
20
Progress Towards Rapid Diagnosis of Measles Vaccine Strains - A Tool to Inform Public Health Interventions. ( 28003421 )
2016
21
Identification of 12 cases of acute measles encephalitis without rash. ( 27601225 )
2016
22
Acute Measles Encephalitis in an Immigrant Syrian Child: Case Report and Review of the Literature. ( 27168928 )
2016
23
Measles and Rubella Seroprevalence Among HIV-Infected And Uninfected Zambian Youth. ( 27879554 )
2016
24
Cell-to-Cell Contact and Nectin-4 Govern Spread of Measles Virus from Primary Human Myeloid Cells to Primary Human Airway Epithelial Cells. ( 27194761 )
2016
25
The Host Cell Receptors for Measles Virus and Their Interaction with the Viral Hemagglutinin (H) Protein. ( 27657109 )
2016
26
Routine vitamin A supplementation for the prevention of blindness due to measles infection in children. ( 27580345 )
2016
27
Vaccine-Preventable Diseases In Pediatric Patients: A Review Of Measles, Mumps, Rubella, And Varicella. ( 27893360 )
2016
28
Measles virus selectively blind to SLAM has oncolytic efficacy against nectin-4-expressing pancreatic cancer cells. ( 27561180 )
2016
29
Measles, mumps, rubella, and varicella seroprevalence in refugees in Germany in 2015. ( 27449329 )
2016
30
Do children who receive an 'early dose' of MMR vaccine during a measles outbreak return for their regularly scheduled dose? A retrospective population-based study. ( 27580838 )
2016
31
Many Inflammatory Bowel Disease Patients Are Not Immune to Measles or Pertussis. ( 27557706 )
2016
32
Measles Outbreak Associated With Low Vaccine Effectiveness Among Adults in Pohnpei State, Federated States of Micronesia, 2014. ( 27186587 )
2016
33
Measles & rubella outbreaks in Maharashtra State, India. ( 27121521 )
2016
34
Global Measles and Rubella Laboratory Network Support for Elimination Goals, 2010-2015. ( 27148917 )
2016
35
Measles-Mumps-Rubella vaccine for children with egg allergy: Is admission for inpatient vaccination necessary? ( 27770112 )
2016
36
Contrasting female-male mortality ratios after routine vaccinations with pentavalent vaccine versus measles and yellow fever vaccine. A cohort study from urban Guinea-Bissau. ( 27475473 )
2016
37
Requirement of HSP90 chaperoning in addition to phosphoprotein for folding but not for supporting enzymatic activities of measles and Nipah virus L polymerases. ( 27170753 )
2016
38
PACT- and RIG-I-Dependent Activation of Type I Interferon Production by a Defective Interfering RNA Derived from Measles Virus Vaccine. ( 26608320 )
2016
39
Measles re-emergence in Northern Italy: Pathways of measles virus genotype D8, 2013-2014. ( 27989661 )
2016
40
A population profile of measles susceptibility in Tianjin, China. ( 27151881 )
2016
41
Unilateral Optic Neuritis: A Rare Complication after Measles-Mumps-Rubella Vaccination in a 30-Year-Old Woman. ( 27195163 )
2016
42
Cotton Mather's medicine, with particular reference to measles. ( 27635032 )
2016
43
Anti-rubella, Mumps and Measles IgG Antibodies in Medical Students of Tehran University. ( 27424140 )
2016
44
Scale-Free Distribution of Local Infection Cluster Sizes of Measles, Rubella, Syphilis and HIV/AIDS: Correlation with Size Distribution of Municipality Population That Was Also Scale-Free. ( 27169948 )
2016
45
Evaluation of impact of measles rubella campaign on vaccination coverage and routine immunization services in Bangladesh. ( 27519586 )
2016
46
Laboratory confirmation of rubella infection in suspected measles cases. ( 27018071 )
2016
47
Aseptic meningitis after measles-mumps-rubella (MMR) vaccination. ( 27181175 )
2016
48
A risk stratification approach to assessing for true cases of measles in a highly vaccinated population. ( 27198177 )
2016
49
Seroprevalence of antibodies to measles, mumps, and rubella, and serologic responses after vaccination among human immunodeficiency virus (HIV)-1 infected adults in Northern Thailand. ( 27138005 )
2016
50
Does oral polio vaccine have non-specific effects on all-cause mortality? Natural experiments within a randomised controlled trial of early measles vaccine. ( 28011813 )
2016

Variations for Measles

Expression for Measles

Search GEO for disease gene expression data for Measles.

Pathways for Measles

Pathways related to Measles according to GeneCards Suite gene sharing:

(show all 47)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
13.96 ADAR CD209 CD40LG CD46 DDX58 EIF2AK2
2
Show member pathways
13.54 EIF2AK2 IFNA1 IFNAR2 IFNB1 IFNG IL2
3
Show member pathways
13.36 ADAR CD40LG DDX58 EIF2AK2 IFNA1 IFNAR2
4
Show member pathways
13.21 FCGR2B IFNG IL2 IL4 STAT1 TLR2
5
Show member pathways
13.02 CD209 IFNA1 IFNAR2 IFNB1 STAT1 TLR2
6
Show member pathways
12.88 CD40LG IFNA1 IFNG IL2 IL4 STAT1
7
Show member pathways
12.84 DDX58 IFIH1 IFNA1 IFNAR2 IFNB1 IFNG
8
Show member pathways
12.77 ADAR DDX58 IFIH1 IFNA1 IFNB1 IFNG
9
Show member pathways
12.71 CD40LG EIF2AK2 IL2 TLR2 TLR3
10
Show member pathways
12.64 CD40LG IFNAR2 IFNG IL2 IL4
11 12.63 IFNA1 IFNAR2 IFNB1 IL2 IL4 TLR2
12
Show member pathways
12.6 IFNG IL2 IL4 STAT1 TLR2
13
Show member pathways
12.57 ADAR DDX58 EIF2AK2 IFNA1 IFNAR2 IFNB1
14
Show member pathways
12.56 IFNA1 IFNAR2 IFNB1 IFNG IL2 IL4
15
Show member pathways
12.41 CD40LG IFNG IL2 IL4
16
Show member pathways
12.35 IFNA1 IFNAR2 IFNB1 IFNG STAT1
17
Show member pathways
12.29 CD40LG IFNG IL4 STAT1 TLR2
18 12.29 CD209 FCGR2B IFNA1 IFNB1 IFNG STAT1
19
Show member pathways
12.27 ADAR CD209 CD46 DDX58 EIF2AK2 FCGR2B
20
Show member pathways
12.24 IFNA1 IFNAR2 IFNB1 IFNG IL2 IL4
21
Show member pathways
12.23 IFNB1 IFNG IL4 STAT1 TLR2
22 12.19 IFNG STAT1 TLR2 TLR3
23 12.19 CD40LG CD46 DDX58 IFIH1 IFNA1 IFNG
24 12.1 FCGR2B IFNAR2 IFNB1 IFNG STAT1
25
Show member pathways
12.06 IL2 STAT1 TLR2 TLR3
26 12.06 CD209 IFNG IL2 IL4 SLAMF1
27
Show member pathways
12.01 IFNG IL2 IL4 STAT1
28
Show member pathways
12 IFNG IL2 STAT1 TLR2 TLR3
29
Show member pathways
11.97 IFNG IL4 STAT1 TLR2 TLR3
30
Show member pathways
11.97 ADAR IFNA1 IFNAR2 IFNB1 IFNG IL2
31 11.92 DDX58 EIF2AK2 IFNA1 IFNAR2 IFNB1 STAT1
32 11.85 IFNG IL2 IL4 STAT1
33 11.82 CD209 IFNB1 IFNG IL2 SLAMF1
34
Show member pathways
11.81 CD40LG IFNG IL2 IL4
35 11.77 IFNG IL2 IL4
36 11.77 CD40LG FCGR2B IL4 SLAMF1 TLR2
37 11.71 IFNA1 IFNAR2 IFNB1 IFNG IL2 STAT1
38 11.69 IFNAR2 IFNG IL2
39
Show member pathways
11.66 CD40LG IFNG IL2
40
Show member pathways
11.65 IFNAR2 IFNG IL2
41 11.54 CD40LG IFNG TLR2
42 11.51 IFNG IL2 IL4
43 11.45 EIF2AK2 IFNB1 IFNG STAT1
44 11.38 CD40LG IFNG IL2 IL4
45 11.33 IFNB1 IFNG IL2 IL4
46 11.24 IFNG IL2 IL4
47
Show member pathways
11.08 ADAR DDX58 EIF2AK2 IFNAR2 STAT1

GO Terms for Measles

Cellular components related to Measles according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.86 CD40LG IFNA1 IFNAR2 IFNB1 IFNG IL2
2 extracellular region GO:0005576 9.85 CD209 CD40LG IFNA1 IFNAR2 IFNB1 IFNG
3 external side of plasma membrane GO:0009897 9.35 CD209 CD40LG IFNG IL4 SLAMF1
4 cell surface GO:0009986 9.17 CD209 CD40LG CD46 MSN SLAMF1 TLR2

Biological processes related to Measles according to GeneCards Suite gene sharing:

(show top 50) (show all 53)
id Name GO ID Score Top Affiliating Genes
1 positive regulation of protein phosphorylation GO:0001934 9.98 IFNG IL2 IL4 TLR3
2 viral process GO:0016032 9.97 CD209 CD46 DDX58 EIF2AK2 FCGR2B IFIH1
3 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.96 CD40LG EIF2AK2 TLR2 TLR3
4 innate immune response GO:0045087 9.96 ADAR CD209 CD46 DDX58 EIF2AK2 IFIH1
5 viral entry into host cell GO:0046718 9.91 CD209 CD46 NECTIN4 SLAMF1
6 adaptive immune response GO:0002250 9.91 CD209 CD46 IFNA1 IFNB1 IFNG IL2
7 B cell differentiation GO:0030183 9.9 CD40LG IFNA1 IFNB1 IL4
8 positive regulation of inflammatory response GO:0050729 9.87 IL2 TLR2 TLR3
9 humoral immune response GO:0006959 9.87 IFNA1 IFNB1 IFNG
10 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.86 IFNG IL2 IL4
11 positive regulation of tumor necrosis factor production GO:0032760 9.86 IFNG TLR2 TLR3
12 positive regulation of interleukin-6 production GO:0032755 9.85 DDX58 TLR2 TLR3
13 negative regulation of viral genome replication GO:0045071 9.85 ADAR EIF2AK2 IFNB1
14 immune system process GO:0002376 9.85 ADAR CD209 CD46 DDX58 EIF2AK2 IFIH1
15 response to exogenous dsRNA GO:0043330 9.84 DDX58 IFNA1 IFNB1 TLR3
16 B cell proliferation GO:0042100 9.83 CD40LG IFNA1 IFNB1
17 type I interferon signaling pathway GO:0060337 9.83 ADAR IFNA1 IFNAR2 IFNB1 STAT1
18 positive regulation of activated T cell proliferation GO:0042104 9.82 IL2 IL4 SLAMF1
19 positive regulation of interleukin-8 production GO:0032757 9.82 DDX58 TLR2 TLR3
20 regulation of type I interferon-mediated signaling pathway GO:0060338 9.81 IFNA1 IFNAR2 IFNB1 STAT1
21 leukocyte cell-cell adhesion GO:0007159 9.8 CD209 CD40LG MSN
22 positive regulation of interferon-beta production GO:0032728 9.8 DDX58 IFIH1 TLR2 TLR3
23 positive regulation of T cell proliferation GO:0042102 9.8 CD40LG CD46 IFNG IL2 IL4
24 positive regulation of peptidyl-serine phosphorylation of STAT protein GO:0033141 9.79 IFNA1 IFNB1 IFNG
25 positive regulation of chemokine production GO:0032722 9.78 EIF2AK2 TLR2 TLR3
26 positive regulation of interleukin-12 production GO:0032735 9.78 CD40LG IFNG TLR2 TLR3
27 cellular response to interferon-beta GO:0035458 9.76 IFNB1 STAT1 TLR3
28 positive regulation of interleukin-10 production GO:0032733 9.76 CD40LG CD46 IL4 TLR2
29 microglial cell activation GO:0001774 9.75 IL4 TLR2 TLR3
30 positive regulation of chemokine biosynthetic process GO:0045080 9.74 IFNG IL4 TLR3
31 response to interferon-alpha GO:0035455 9.73 ADAR EIF2AK2 IFNAR2
32 positive regulation of isotype switching to IgG isotypes GO:0048304 9.72 IFNG IL2 IL4
33 cellular response to exogenous dsRNA GO:0071360 9.71 IFNB1 TLR3
34 regulation of interferon-gamma-mediated signaling pathway GO:0060334 9.71 IFNG STAT1
35 I-kappaB phosphorylation GO:0007252 9.71 TLR2 TLR3
36 positive regulation of interferon-alpha production GO:0032727 9.71 DDX58 IFIH1
37 positive regulation of regulatory T cell differentiation GO:0045591 9.7 CD46 IL2
38 response to interferon-beta GO:0035456 9.7 IFNAR2 STAT1
39 positive regulation of MHC class II biosynthetic process GO:0045348 9.7 IFNG IL4
40 detection of virus GO:0009597 9.7 DDX58 IFIH1 TLR3
41 cellular response to dsRNA GO:0071359 9.69 IFNB1 TLR3
42 negative regulation of T-helper 17 cell differentiation GO:2000320 9.67 IL2 IL4
43 positive regulation of toll-like receptor signaling pathway GO:0034123 9.67 TLR2 TLR3
44 interleukin-10 production GO:0032613 9.65 CD46 TLR2
45 cytoplasmic pattern recognition receptor signaling pathway in response to virus GO:0039528 9.64 DDX58 IFIH1
46 regulation of type III interferon production GO:0034344 9.63 DDX58 IFIH1
47 response to virus GO:0009615 9.56 ADAR DDX58 EIF2AK2 IFIH1 IFNAR2 IFNB1
48 defense response to virus GO:0051607 9.32 ADAR DDX58 EIF2AK2 IFIH1 IFNA1 IFNAR2
49 positive regulation of transcription from RNA polymerase II promoter GO:0045944 10.22 DDX58 IFNB1 IFNG IL2 IL4 STAT1
50 immune response GO:0006955 10.13 CD40LG FCGR2B IFNG IL2 IL4 TLR2

Molecular functions related to Measles according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 receptor activity GO:0004872 9.65 CD46 NECTIN4 SLAMF1 TLR2 TLR3
2 cytokine receptor binding GO:0005126 9.5 IFNA1 IFNB1 IL4
3 virus receptor activity GO:0001618 9.46 CD209 CD46 NECTIN4 SLAMF1
4 cytokine activity GO:0005125 9.43 CD40LG IFNA1 IFNB1 IFNG IL2 IL4
5 hydrolase activity, acting on acid anhydrides GO:0016817 9.37 DDX58 IFIH1
6 double-stranded RNA binding GO:0003725 9.02 DDX58 EIF2AK2 IFIH1 MSN TLR3

Sources for Measles

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