MCID: MCK002
MIFTS: 36

Meckel's Diverticulum malady

Gastrointestinal diseases category

Summaries for Meckel's Diverticulum

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63Wikipedia, 46OMIM, 32MalaCards
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Wikipedia:63 A Meckel\'s diverticulum, a true congenital diverticulum, is a slight bulge in the small intestine... more...

MalaCards: Meckel's Diverticulum, also known as meckel diverticulum, is related to appendicitis and intussusception. An important gene associated with Meckel's Diverticulum is FOXA2 (forkhead box A2). The compounds c-peptide and guanidine have been mentioned in the context of this disorder. Affiliated tissues include small intestine, colon and bone.

Description from OMIM:46 155140

Aliases & Classifications for Meckel's Diverticulum

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Sources:
8Disease Ontology, 60UMLS, 56SNOMED-CT, 39NCIt, 46OMIM, 34MeSH, 27ICD9CM, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Gastrointestinal diseases


Aliases & Descriptions:

meckel's diverticulum 8
meckel diverticulum 8 60
persistent vitelline duct 8


External Ids:

Disease Ontology8 DOID:9487
NCIt39 C12264
OMIM46 155140
MeSH34 D008467
ICD9CM27 751.0
ICD1025 Q43.0

Related Diseases for Meckel's Diverticulum

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17GeneCards, 18GeneDecks
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Graphical network of diseases related to Meckel's Diverticulum:



Diseases related to meckel's diverticulum

Clinical Features for Meckel's Diverticulum

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46OMIM
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Clinical features from OMIM:

155140

Drugs & Therapeutics for Meckel's Diverticulum

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Meckel's Diverticulum

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Anatomical Context for Meckel's Diverticulum

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32MalaCards
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MalaCards organs/tissues related to Meckel's Diverticulum:

32
Small intestine, Colon, Bone, Pancreas, Appendix, Liver, Kidney, Spleen

Animal Models for Meckel's Diverticulum or affiliated genes

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Publications for Meckel's Diverticulum

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50PubMed
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Articles related to Meckel's Diverticulum:

(show top 50)    (show all 507)
idTitleAuthorsYear
1
Perforation of Meckel's diverticulum by a fish bone presenting as acute appendicitis: a case report. (24088307)
2013
2
Uncommon Presentation of Meckel's Diverticulum in Young Age. (24023597)
2013
3
Perforation of Meckel's diverticulum by an intact fish bone. (23429021)
2013
4
Endoscopic ultrasound with double-balloon endoscopy for the diagnosis of inverted Meckel's diverticulum: a case report. (23021405)
2012
5
Perforated Meckel's diverticulum in a 1-day-old neonate. (22273297)
2012
6
Perforated Meckel's diverticulum: a diagnostic dilemma. (22015135)
2011
7
Capsule retention in a giant Meckel's diverticulum containing multiple enteroliths. (21915841)
2011
8
Acute appendicitis and carcinoid tumor in Meckel's diverticulum. Three pathologies in one: a case report. (21887558)
2011
9
An uncommon location of Meckel's diverticulum or small intestine duplication? Case report and literature review. (22166720)
2011
10
Virtual enteroscopic images of inverted Meckel's diverticulum. (21621494)
2011
11
Helicobacter species and gut bacterial DNA in Meckel's diverticulum and the appendix. (22039324)
2011
12
Double heterotopic pancreas and Meckel's diverticulum in a child: do they have a common origin? (20718198)
2010
13
Perforation of Meckel's diverticulum secondary to a large faecolith. (22461854)
2010
14
Double-balloon enteroscopy for bleeding Meckel's diverticulum in a child younger than 4 years of age. (19243766)
2009
15
Bleeding Meckel's diverticulum in a 4-month-old infant: Treatment with laparoscopic diverticulectomy. A case report and review of the literature. (21694825)
2009
16
The incidental Meckel's diverticulum in trauma: a case report and literature review. (18277297)
2009
17
Perforation of Meckel's diverticulum by a fishbone. (18959720)
2008
18
Crohn's disease in a Meckel's diverticulum: report of a case. (17579870)
2008
19
Obscure gastrointestinal bleeding due to Meckel's diverticulum: unusual capsule endoscopic finding as polyp-like lesion. (18709619)
2008
20
Adenocarcinoma of the appendix and a Meckel's diverticulum in a case of acute appendicitis. (17848820)
2007
21
High incidence of symptomatic Meckel's diverticulum in patients less than fifty years of age: an indication for resection. (17375785)
2007
22
An unusual manifestation of Meckel's diverticulum: strangulated paraumbilical hernia. (16807577)
2006
23
Carcinoid of the Meckel's diverticulum: case report and review of literature. (19858601)
2006
24
Gastrointestinal: Meckel's diverticulum. (16509879)
2006
25
M2A video capsule lodged in the Meckel's diverticulum. (16733133)
2006
26
Rectal Meckel's diverticulum: an unusual cause of rectal bleeding. (16080013)
2006
27
Intermittent small-bowel obstruction caused by gastric adenocarcinoma in a Meckel's diverticulum. (15672086)
2005
28
Bleeding Meckel's diverticulum. (15804479)
2005
29
Meckel's diverticulum in a male calf. (15072203)
2004
30
Perforation of Meckel's diverticulum by a chicken bone, a rare complication: report of a case. (15221556)
2004
31
Meckel's diverticulum: a neglected (or deliberately ignored) entity. (15553441)
2004
32
Images in clinical medicine. A bleeding Meckel's diverticulum. (12944585)
2003
33
Stromal tumor in a perforated Meckel's diverticulum: a case report. (12520847)
2002
34
Laparoscopic resection of perforated Meckel's diverticulum in a patient with clinical symptoms of acute appendicitis. (12085134)
2002
35
Surgical management and complications of Meckel's diverticulum in 90 patients. (12022375)
2002
36
Meckel's diverticulum associated with ileal volvulus in a neonate. (12415402)
2002
37
Axial torsion of Meckel's diverticulum presenting as a pelvic mass. (11727027)
2001
38
Ectopic gastric mucosa presenting as a polypoid mass within a Meckel's diverticulum. (11354751)
2001
39
The role of heterotopic gastric mucosa with or without colonization of Helicobacter pylori upon the diverse symptomatology of Meckel's diverticulum in children. (11765161)
2001
40
Inverted Meckel's diverticulum as a source of chronic gastrointestinal blood loss. (10876194)
2000
41
Procedure guideline for gastrointestinal bleeding and Meckel's diverticulum scintigraphy. Society of Nuclear Medicine. (10405149)
1999
42
The role of laparoscopy in symptomatic Meckel's diverticulum. (10526047)
1999
43
Gallstone ileus with impaction at the neck of a Meckel's diverticulum. (10319010)
1998
44
Meckel of Meckel's diverticulum. (9496945)
1998
45
Meckel's diverticulum: a ten-year experience. (9124758)
1997
46
Pseudolipoma of inverted Meckel's diverticulum: clinical, radiological and pathological correlation. (9228106)
1997
47
Leiomyosarcoma originating in Meckel's diverticulum: report of a case and a review of 59 cases in the English literature. (9306549)
1997
48
Intrauterine intussusception due to Meckel's diverticulum as a cause of ileal atresia: analysis of 2 cases. (8721182)
1996
49
Angiodysplasia of the colon, Meckel's diverticulum and cardiac malformation. A case report. (2131955)
1990
50
Partial duodenal obstruction secondary to Meckel's diverticulum. (3682541)
1987

Genetic Variations for Meckel's Diverticulum

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Expression for genes affiliated with Meckel's Diverticulum

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Meckel's Diverticulum

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Pathways for genes affiliated with Meckel's Diverticulum

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Compounds for genes affiliated with Meckel's Diverticulum

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44Novoseek, 11DrugBank, 24HMDB
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Compounds related to Meckel's Diverticulum according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1c-peptide449.7SERPINE1, FOXA2
2guanidine44 11 2411.3SERPINE1, HRH2

GO Terms for genes affiliated with Meckel's Diverticulum

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16Gene Ontology
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Biological processes related to Meckel's Diverticulum according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1chromatin modificationGO:0165689.5HDAC11, FOXA2

Products for genes affiliated with Meckel's Diverticulum

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  • Antibodies
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Sources for Meckel's Diverticulum

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet