MCID: MCK002
MIFTS: 35

Meckel's Diverticulum malady

Categories: Gastrointestinal diseases

Aliases & Classifications for Meckel's Diverticulum

Aliases & Descriptions for Meckel's Diverticulum:

Name: Meckel's Diverticulum 12 14
Meckel Diverticulum 12 29 42 69
Persistent Vitelline Duct 12

Characteristics:

HPO:

32
meckel's diverticulum:
Inheritance autosomal dominant inheritance


Classifications:



External Ids:

Disease Ontology 12 DOID:9487
ICD10 33 Q43.0
ICD9CM 35 751.0
MeSH 42 D008467
NCIt 47 C12264
UMLS 69 C0025037

Summaries for Meckel's Diverticulum

MalaCards based summary : Meckel's Diverticulum, also known as meckel diverticulum, is related to meckel's diverticulum cancer and omphalomesenteric cyst, and has symptoms including meckel diverticulum An important gene associated with Meckel's Diverticulum is FOXA2 (Forkhead Box A2), and among its related pathways/superpathways is Cardiac Progenitor Differentiation. Affiliated tissues include small intestine, bone and colon, and related phenotypes are Increased Sindbis virus (SINV) infection and liver/biliary system

Wikipedia : 71 A Meckel\'s diverticulum, a true congenital diverticulum, is a slight bulge in the small intestine... more...

Related Diseases for Meckel's Diverticulum

Graphical network of the top 20 diseases related to Meckel's Diverticulum:



Diseases related to Meckel's Diverticulum

Symptoms & Phenotypes for Meckel's Diverticulum

Human phenotypes related to Meckel's Diverticulum:

32
id Description HPO Frequency HPO Source Accession
1 meckel diverticulum 32 HP:0002245

GenomeRNAi Phenotypes related to Meckel's Diverticulum according to GeneCards Suite gene sharing:

26
id Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased Sindbis virus (SINV) infection GR00310-A-1 8.92 FOXA2 HRH2 STK10
2 Increased Sindbis virus (SINV) infection GR00310-A-2 8.92 STK10

MGI Mouse Phenotypes related to Meckel's Diverticulum:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 liver/biliary system MP:0005370 8.92 ACOT7 FOXA2 KIT SERPINE1

Drugs & Therapeutics for Meckel's Diverticulum

Search Clinical Trials , NIH Clinical Center for Meckel's Diverticulum

Cochrane evidence based reviews: meckel diverticulum

Genetic Tests for Meckel's Diverticulum

Genetic tests related to Meckel's Diverticulum:

id Genetic test Affiliating Genes
1 Meckel Diverticulum 29

Anatomical Context for Meckel's Diverticulum

MalaCards organs/tissues related to Meckel's Diverticulum:

39
Small Intestine, Bone, Colon, Pancreas, Appendix, Liver, Kidney

Publications for Meckel's Diverticulum

Articles related to Meckel's Diverticulum:

(show top 50) (show all 616)
id Title Authors Year
1
A Rare Entity of Gastrointestinal Stromal Tumour Arising from a Meckel's Diverticulum: a Case Report. ( 28092014 )
2017
2
Meckel's diverticulitis: a rare entity of Meckel's diverticulum. ( 28064243 )
2017
3
Phytobezoar impaction in a Meckel's diverticulum; a rare cause of bowel obstruction: Case report and review of literature. ( 28012337 )
2016
4
Perforated Gastrointestinal Stromal Tumor of the Meckel's Diverticulum: a Case Report and Review of Literature. ( 27994335 )
2016
5
Meckel's diverticulum in an adult: an obscure presentation of gastrointestinal bleeding. ( 27126093 )
2016
6
Atypical presentation of a Meckel's diverticulum. ( 26884080 )
2016
7
Capsule retention in a Meckel's diverticulum for 7.5 years. ( 28032666 )
2016
8
Laparoscopic management of an axially torsed gangrenous Meckel's diverticulum in a child. ( 27502885 )
2016
9
Mesenteric Meckel's diverticulum or intestinal duplication cyst: A case report with review of literature. ( 27449764 )
2016
10
Meckel's diverticulum complicated with gastro-intestinal stromal tumor: Case report. ( 26936384 )
2016
11
Giant Meckel's diverticulum torsion that mimics adnexal pathology. ( 27261632 )
2016
12
A massive bleeding from a gastrointestinal stromal tumor of a Meckel's diverticulum. ( 27483571 )
2016
13
Intestinal hemorrhage caused by Meckel's diverticulum with ectopic gastric mucosa on polypoid lesion: a case report. ( 27815920 )
2016
14
Recurrent Small-Bowel Obstruction Caused by a Meckel's Diverticulum Diagnosed on Video Capsule Endoscopy. ( 26923733 )
2016
15
Traumatic rupture of a Meckel's diverticulum due to blunt abdominal trauma in a soccer game: A case report. ( 26701844 )
2016
16
A gastrointestinal stromal tumor found in perforated Meckel's diverticulum. ( 27411534 )
2016
17
The many faces of Meckel's diverticulum and its complications. ( 27492813 )
2016
18
Congenital diaphragmatic hernia, Meckel's diverticulum and malrotation in a 3-month-old infant. ( 27251525 )
2016
19
Meckel's diverticulum enteroliths causing small bowel obstruction. ( 26762683 )
2016
20
Comorbid Meckel's diverticulum and omphalomesenteric cyst evaluated by small bowel series under double-balloon enteroscopy:a case report. ( 27052394 )
2016
21
Gallstone ileus associated with impaction at Meckel's diverticulum: Case report and literature review. ( 27933137 )
2016
22
Mesenteric Meckel's diverticulum: an unusual cause of small bowel intussusception. ( 27060074 )
2016
23
Inverted Meckel's diverticulum preoperatively diagnosed using double-balloon enteroscopy. ( 27158212 )
2016
24
An unusual case of intraabdominal abscess and acute abdomen caused by axial torsion of a Meckel's diverticulum. ( 26955478 )
2016
25
Perforated Meckel's Diverticulum. ( 27574358 )
2016
26
Laparoscopic surgery for small-bowel obstruction caused by Meckel's diverticulum. ( 26981191 )
2016
27
Meckel's diverticulum and bowel obstruction due to phytobezoar: a case report. ( 27345602 )
2016
28
Perforated Meckel's diverticulum containing a carcinoid tumor successfully treated by the laparoscopic approach: Case report. ( 27251847 )
2016
29
Meckel's diverticulum in children: Our 12-year experience. ( 28051045 )
2016
30
Diagnostic laparoscopy for neonatal perforated Meckel's diverticulum. ( 26917924 )
2016
31
Perforated Meckel's Diverticulum in a 3-day-old Neonate; A Case Report. ( 27957297 )
2016
32
A Rare Case of a Gastrointestinal Stromal Tumor (GIST) Presenting as a Perforated Meckel's Diverticulum. ( 26820464 )
2016
33
Capsule endoscopy is useful diagnostic tool for diagnosing Meckel's diverticulum. ( 26854797 )
2016
34
Diagnosis of Bleeding Meckel's Diverticulum in Adults. ( 27626641 )
2016
35
A curious case of Meckel's diverticulum. ( 27770121 )
2016
36
Pediatric Meckel's Diverticulum: Report of 208 Cases and Review of the Literature. ( 27064958 )
2016
37
Intestinal Duplication Cyst Misdiagnosed as Meckel's Diverticulum. ( 26830996 )
2016
38
Adult Intussusception Caused by Inverted Meckel's Diverticulum Containing Mesenteric Heterotopic Pancreas and Smooth Muscle Bundles. ( 27498547 )
2016
39
Many faces of Meckel's diverticulum and its complications. ( 26932405 )
2016
40
Gastrointestinal stromal tumor of the vermiform appendix mimicking Meckel's diverticulum: Case report with literature review. ( 26895113 )
2016
41
Genomic mapping of pathways in endometrial adenocarcinoma and a gastrointestinal stromal tumor located in Meckel's diverticulum. ( 26893683 )
2016
42
Incremental value of SPECT/CT in detection of Meckel's diverticulum in a 10-year-old child. ( 27540503 )
2016
43
Inverted Meckel's Diverticulum with Intussusception and Ulceration Diagnosed after Rectal Double-Balloon Enteroscopy. ( 28008404 )
2016
44
Balloon-assisted enteroscopy for suspected Meckel's diverticulum and indefinite diagnostic imaging workup. ( 27803776 )
2016
45
Meckel's diverticulum perforation by a fish bone: A case report. ( 27744259 )
2016
46
Unusual presentation of a Meckel's diverticulum: A case report. ( 26413922 )
2015
47
Concurrent perforated Meckel's diverticulum and intestinal malrotation in an 8-year-old boy. ( 26511995 )
2015
48
Simultaneous occurrence of Meckel's diverticulum and patent urachus. ( 26156836 )
2015
49
Technetium-99m-pertechnetate scintigraphy in children with symptomatic Meckel's diverticulum. ( 25706672 )
2015
50
Aneurysmal Rupture of a Mesodiverticular Band to a Meckel's Diverticulum. ( 25688323 )
2015

Variations for Meckel's Diverticulum

Expression for Meckel's Diverticulum

Search GEO for disease gene expression data for Meckel's Diverticulum.

Pathways for Meckel's Diverticulum

Pathways related to Meckel's Diverticulum according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1 10.35 FOXA2 KIT

GO Terms for Meckel's Diverticulum

Biological processes related to Meckel's Diverticulum according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 signal transduction by protein phosphorylation GO:0023014 9.16 KIT STK10
2 visual learning GO:0008542 8.96 HRH2 KIT
3 digestive tract development GO:0048565 8.8 CLMP HRH2 KIT

Molecular functions related to Meckel's Diverticulum according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 protease binding GO:0002020 8.62 KIT SERPINE1

Sources for Meckel's Diverticulum

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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