MCID: MCK002
MIFTS: 36

Meckel's Diverticulum malady

Gastrointestinal diseases category

Summaries for Meckel's Diverticulum

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63Wikipedia, 46OMIM, 32MalaCards
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Wikipedia:63 A Meckel\'s diverticulum, a true congenital diverticulum, is a slight bulge in the small intestine... more...

MalaCards: Meckel's Diverticulum, also known as meckel diverticulum, is related to appendicitis and intussusception. An important gene associated with Meckel's Diverticulum is FOXA2 (forkhead box A2). The compounds c-peptide and guanidine have been mentioned in the context of this disorder. Affiliated tissues include small intestine, colon and bone.

Description from OMIM:46 155140

Aliases & Classifications for Meckel's Diverticulum

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Sources:
8Disease Ontology, 60UMLS, 56SNOMED-CT, 39NCIt, 46OMIM, 34MeSH, 27ICD9CM, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Gastrointestinal diseases


Aliases & Descriptions:

meckel's diverticulum 8
meckel diverticulum 8 60
persistent vitelline duct 8


External Ids:

Disease Ontology8 DOID:9487
NCIt39 C12264
OMIM46 155140
MeSH34 D008467
ICD9CM27 751.0
ICD1025 Q43.0

Related Diseases for Meckel's Diverticulum

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17GeneCards, 18GeneDecks
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Graphical network of diseases related to Meckel's Diverticulum:



Diseases related to meckel's diverticulum

Clinical Features for Meckel's Diverticulum

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46OMIM
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Clinical features from OMIM:

155140

Drugs & Therapeutics for Meckel's Diverticulum

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Meckel's Diverticulum

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Anatomical Context for Meckel's Diverticulum

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32MalaCards
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MalaCards organs/tissues related to Meckel's Diverticulum:

32
Small intestine, Colon, Bone, Pancreas, Appendix, Spleen, Kidney, Liver

Animal Models for Meckel's Diverticulum or affiliated genes

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Publications for Meckel's Diverticulum

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50PubMed
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Articles related to Meckel's Diverticulum:

(show top 50)    (show all 507)
idTitleAuthorsYear
1
Mesenteric Meckel's diverticulum. (23934471)
2013
2
Adenocarcinoma arising from Meckel's diverticulum in the ileum with malrotation of the midgut. (23741695)
2013
3
Mesenteric localization of Meckel's diverticulum. (23934472)
2013
4
Double-balloon enteroscopy for diagnosis of Meckel's diverticulum: comparison with operative findings and capsule endoscopy. (23305600)
2013
5
A microscopically calcified Meckel's diverticulum: a histopathological perspective of a case of both gastric and pancreatic mucosae. (23440988)
2013
6
Wireless Capsule Endoscopy Detects Meckel's Diverticulum in a Child with Unexplained Intestinal Blood Loss. (23139657)
2012
7
Computed tomographic diagnosis of incarcerated Meckel's diverticulum in a patient with bilateral spigelian hernia. (21800227)
2012
8
Inverted Meckel's diverticulum as a cause of occult lower gastrointestinal hemorrhage. (23155346)
2012
9
Ectopic kidney mimicking a Meckel's diverticulum on Tc-99m pertechnetate scan. (22064118)
2011
10
Meckel's diverticulum: a review. (21322060)
2011
11
Meckel's diverticulum, a "hot spot" for cancer. (21217508)
2011
12
Acute abdomen in infant. Meckel's diverticulum and ileo-ileocolic intussusception. (21183082)
2011
13
Meckel's diverticulum-Revisited. (20065566)
2010
14
A rare case of complicated Meckel's diverticulum. Case report and images. (21456482)
2010
15
Perforation of Meckel's diverticulum caused by a chicken bone: a case report. (19192283)
2009
16
Gangrene due to axial torsion of a Giant Meckel's Diverticulum containing multiple stones in the lumen: a case report. (19829920)
2009
17
Rectal Meckel's diverticulum. (19787581)
2009
18
An incarcerated femoral hernia containing a Meckel's diverticulum. (19350867)
2009
19
Double-balloon enteroscopy for the diagnosis of Meckel's diverticulum in a 50-year-old man with obscure gastrointestinal bleeding. (19344788)
2009
20
Torsion and gangrene of a Meckel's diverticulum. (19278165)
2009
21
Gastrointestinal bleeding diagnosed using video capsule endoscopy. Meckel's diverticulum. (19671555)
2009
22
Radiological features of Meckel's diverticulum and its complications. (19589428)
2009
23
Electronic clinical challenges and images in GI. Meckel's diverticulum. (18395064)
2008
24
Laparoscopic management of complicated Meckel's diverticulum in children: a 10-year review. (18322735)
2008
25
Calcified Meckel's diverticulum: an unusual incidental finding during laparoscopy. (17368293)
2007
26
Imaging manifestations of Meckel's diverticulum. (17579156)
2007
27
Meckel's diverticulum: a systematic review. (17021300)
2006
28
Capsule endoscopy for the detection of bleeding Meckel's diverticulum. A case report. (16971877)
2006
29
Recurrent torsion of a giant Meckel's diverticulum. (16047474)
2005
30
Meckel's diverticulum masked by a long period of gastric symptoms--a case report. (16184729)
2005
31
Identification of a Meckel's diverticulum by wireless capsule endoscopy. (15933947)
2005
32
Laparoscopic management of Meckel's diverticulum in children. (15793736)
2005
33
The significance of Meckel's diverticulum in appendicitis--a retrospective analysis of 233 cases. (15776296)
2005
34
Perforation of Meckel's diverticulum by roundworm. (15778523)
2005
35
Migrating calcified enterolith and chronic anemia: an unusual case presentation of a Meckel's diverticulum. (15630649)
2004
36
Rare mesenteric location of Meckel's diverticulum, a forgotten entity: a case study aboard USS Kitty Hawk. (15586511)
2004
37
Small bowel obstruction in an adolescent: a case of Meckel's diverticulum. (15615202)
2004
38
Laparoscopic management of Meckel's diverticulum in adults. (12582775)
2003
39
Gastrointestinal bleeding in adult patients with Meckel's diverticulum: the role of technetium 99m pertechnetate scan. (12540005)
2002
40
Inverted Meckel's diverticulum as a leading point for ileoileal intussusception in an adult: case report. (12172999)
2002
41
Laparoscopy-assisted resection of complicated Meckel's diverticulum. (12496556)
2002
42
The value of angiography in diagnosis of Meckel's diverticulum: case report. (11190383)
2000
43
Gastrointestinal bleeding in infants and children: Meckel's diverticulum and intestinal duplication. (10573430)
1999
44
Massive gastrointestinal bleeding from Meckel's diverticulum in a 91-year-old man. (9715222)
1998
45
Scintigraphic pattern of intestinal duplication on a Meckel's diverticulum scan. (9790054)
1998
46
Torsion of a Meckel's diverticulum: sonographic findings. (9716631)
1998
47
Laparoscopy: the ultimate diagnostic tool for a bleeding Meckel's diverticulum. (9137168)
1997
48
Bay leaf perforation of Meckel's diverticulum. (9126131)
1997
49
Abdominal angiostrongyliasis mimicking acute appendicitis and Meckel's diverticulum: report of a case in the United States and review. (1576277)
1992
50
Antenatal perforation of Meckel's diverticulum presenting as an inflamed hydrocele. (3794961)
1986

Genetic Variations for Meckel's Diverticulum

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Expression for genes affiliated with Meckel's Diverticulum

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Meckel's Diverticulum

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Pathways for genes affiliated with Meckel's Diverticulum

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Compounds for genes affiliated with Meckel's Diverticulum

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44Novoseek, 11DrugBank, 24HMDB
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Compounds related to Meckel's Diverticulum according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1c-peptide449.7SERPINE1, FOXA2
2guanidine44 11 2411.3SERPINE1, HRH2

GO Terms for genes affiliated with Meckel's Diverticulum

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16Gene Ontology
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Biological processes related to Meckel's Diverticulum according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1chromatin modificationGO:0165689.5HDAC11, FOXA2

Products for genes affiliated with Meckel's Diverticulum

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  • Antibodies
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  • Antibodies

Sources for Meckel's Diverticulum

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet