MCID: MCN007
MIFTS: 43

Meconium Aspiration Syndrome malady

Rare diseases, Fetal diseases, Respiratory diseases categories

Aliases & Classifications for Meconium Aspiration Syndrome

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Sources:
10Disease Ontology, 45NIH Rare Diseases, 47Novoseek, 12DISEASES, 51Orphanet, 65UMLS, 36MeSH, 59SNOMED-CT, 42NCIt, 28ICD10 via Orphanet, 37MESH via Orphanet, 66UMLS via Orphanet, 27ICD10
See all sources

Aliases & Descriptions for Meconium Aspiration Syndrome:

Name: Meconium Aspiration Syndrome 10 45 47 12 51 65 36
Neonatal Aspiration of Meconium 10
 
Meconium Aspiration 10
Mas 45


Classifications:



Characteristics (Orphanet epidemiological data):

51
meconium aspiration syndrome:
Inheritance: Not applicable; Prevalence: 1-9/100000 (Europe); Age of onset: Infancy,Neonatal


External Ids:

Disease Ontology10 DOID:11049
MeSH36 D008471
NCIt42 C87093
Orphanet51 70588
ICD10 via Orphanet28 P24.0
MESH via Orphanet37 D008471
UMLS via Orphanet66 C0025048
ICD1027 P24.0

Summaries for Meconium Aspiration Syndrome

About this section
NIH Rare Diseases:45 Meconium aspiration syndrome is a serious condition in which a newborn breathes a mixture of meconium and amniotic fluid into the lungs around the time of delivery. this can cause breathing difficulties due to swelling (inflammation) in the baby's lungs after birth. treatment may include suctioning the newborn's mouth as soon as the head emerges during delivery, deep suctioning of the windpipe, antibiotics to treat infection, oxygen to keep blood levels normal, and radiant heat to maintain body temperature. in severe cases, the baby may need assistance breathing (ventilator). last updated: 1/12/2012

MalaCards based summary: Meconium Aspiration Syndrome, also known as neonatal aspiration of meconium, is related to pneumonia and pneumothorax. An important gene associated with Meconium Aspiration Syndrome is EDN1 (Endothelin 1), and among its related pathways are Prostaglandin Synthesis and Regulation and TSLP Signaling Pathway. Affiliated tissues include lung and uterus, and related mouse phenotypes are renal/urinary system and tumorigenesis.

Wikipedia:68 Meconium aspiration syndrome (MAS) also known as neonatal aspiration of meconium is a medical condition... more...

Related Diseases for Meconium Aspiration Syndrome

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Diseases related to Meconium Aspiration Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 267)
idRelated DiseaseScoreTop Affiliating Genes
1pneumonia30.2CXCL8, IL6, SCGB1A1, TNF
2pneumothorax29.7CXCL8, IL6, SCGB1A1, SFTPB, TNF
3asthma29.0CSF2, CXCL8, EDN1, IFNG, IL6, SCGB1A1
4child syndrome10.6
5pulmonary hypertension10.6
6placenta disease10.6
7respiratory system disease10.6
8kid syndrome10.6
9respiratory failure10.4
10pulmonary hypertension, neonatal10.3
11adult syndrome10.3
12newborn respiratory distress syndrome10.3
13neonatal respiratory failure10.3
14cork-handlers' disease10.3
15uterine disease10.3
16respiratory distress syndrome, infant10.3
17hypoxia10.3
18diabetic ketoacidosis10.3CXCL8, IL6
19papilledema10.2CXCL8, IL6
20chorioamnionitis10.2CXCL8, IL6
21cicatricial entropion10.2CXCL8, IL6
22preterm premature rupture of the membranes10.2CXCL8, IL6
23plantar fasciitis10.2CXCL8, IL6
24vaginal glandular tumor10.2CXCL8, IL6
25vascular cancer10.2CXCL8, IL6
26narcissistic personality disorder10.2CXCL8, IL6
27parathyroid cancer, childhood10.2SCGB1A1, SFTPB
28hair defect with photosensitivity and mental retardation10.2CXCL8, TNF
29dermatitis10.2CXCL8, TNF
30mycobacterium chelonae10.2CXCL8, TNF
31tuberculous uveitis10.2CXCL8, TNF
32hypertension, essential10.2
33atopy10.2
34pulmonary hypertension, primary, 410.2
35hepatocellular carcinoma10.2
36anemia, sideroblastic, pyridoxine-refractory, autosomal recessive10.2
37short syndrome10.2
38trichohepatoenteric syndrome 210.2
39pulmonary hypertension, primary, 310.2
40periodic fever, familial10.2
41pulmonary hypertension, primary, 210.2
42alveolar capillary dysplasia with misalignment of pulmonary veins10.2
43adult respiratory distress syndrome10.2
44brain ischemia10.2
45thrombocytopenia10.2
46tracheal disease10.2
47good syndrome10.2
48pharyngitis10.2
49persistent fetal circulation syndrome10.2
50patent ductus arteriosus10.2

Graphical network of the top 20 diseases related to Meconium Aspiration Syndrome:



Diseases related to meconium aspiration syndrome

Symptoms for Meconium Aspiration Syndrome

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Drugs & Therapeutics for Meconium Aspiration Syndrome

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Drugs for Meconium Aspiration Syndrome (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 8)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Sildenafilapproved, investigationalPhase 4296139755-83-25212
Synonyms:
1-((3-(4,7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo(4,3-D)pyrimidin-5-yl)-4-ethoxyphenyl)sulfonyl)-4-methylpiperazine
1-((3-(4,7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo(4,3-d)pyrimidin-5-yl)-4-ethoxyphenyl)sulfonyl)-4-methylpiperazine
1-((3-(6,7-dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo(4,3-d)pyrimidin-5-yl)-4-ethoxyphenyl)sulfonyl)-4-methylpiperazine citrate
139755-83-2
171599-83-0 (citrate)
1udt
1xos
2h42
5-(2-ethoxy-5-(4-methylpiperazin-1-ylsulfonyl)phenyl)-1-methyl-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-7(6H)-one
5-[2-Ethoxy-5-(4-methyl-piperazine-1-sulfonyl)-phenyl]-1-methyl-3-propyl-1,6-dihydro-pyrazolo[4,3-d]pyrimidin-7-one (Sildenafil or Viagra)
5-[2-Ethoxy-5-(4-methyl-piperazine-1-sulfonyl)-phenyl]-1-methyl-3-propyl-1,6-dihydro-pyrazolo[4,3-d]pyrimidin-7-one(Sildenafil)
5-[2-ethoxy-5-(4-methylpiperazin-1-yl)sulfonylphenyl]-1-methyl-3-propyl-4H-pyrazolo[4,3-d]pyrimidin-7-one
5-{2-(ethyloxy)-5-[(4-methylpiperazin-1-yl)sulfonyl]phenyl}-1-methyl-3-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one
5-{2-ethoxy-5-[(4-methylpiperazin-1-yl)sulfonyl]phenyl}-1-methyl-3-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one
AC-938
AC1L1JUI
Ambap139755-83-2
Aphrodil
Aphrodil (TN)
BAS 04213629
BIDD:GT0352
BRD-K79759585-001-02-1
BSPBio_003424
C07259
C22H30N6O4S
CHEBI:9139
CHEMBL192
CID5212
Caverta
D08514
DB00203
DivK1c_006894
HMS1684K08
HMS1922B19
HMS2089M12
HMS2093O17
HSDB 7305
 
I06-0023
Jsp002373
KBio1_001838
KBio2_002035
KBio2_004603
KBio2_007171
KBio3_002927
KBioGR_001052
KBioSS_002035
LS-111655
MLS001240224
MLS001304737
MolPort-001-995-394
MolPort-002-885-861
NCGC00095099-01
NCGC00095099-02
NCGC00159496-02
Revatio
SMR000752512
SPBio_001775
SPECTRUM1504099
Sildenafil
Sildenafil (INN)
Sildenafil Citrate
Sildenafil Viagra
Sildenafil [INN:BAN]
Sildenafil citrate
SpecPlus_000798
Spectrum2_001648
Spectrum3_001892
Spectrum4_000586
Spectrum5_001508
Spectrum_001555
UK-92,480-10
UK-92480
UNII-3M7OB98Y7H
VIA
Viagra
sildenafil
2Phosphodiesterase 5 InhibitorsPhase 4518
3Pulmonary SurfactantsPhase 4, Phase 399
4Poractant alfaPhase 422
5
Nitric OxideapprovedPhase 354010102-43-9145068
Synonyms:
(.)NO
(NO)(.)
10102-43-9
14332-28-6
295566_ALDRICH
51005-20-0
51005-21-1
53851-19-7
90452-29-2
AC1L1ADQ
AC1L3QHF
AC1Q6QZ0
AR-1K7463
Bioxyde d'azote
Bioxyde d'azote [French]
C00533
CCRIS 4319
CHEMBL1200689
CHEMBL1234765
CID145068
CID945
D00074
D009569
DB00435
EDRF
EINECS 233-271-0
Endogenous Nitrate Vasodilator
Endothelium-Derived Nitric Oxide
HNO
HSDB 1246
INOmax
INOmax (TN)
Inomax
LS-192158
LS-7547
MolPort-003-929-452
Mononitrogen monoxide
Monoxide, Mononitrogen
Monoxide, Nitrogen
Monoxido de nitrogeno
Monoxyde d'azote
NITRIC-OXIDE
NO
NO(.)
Nitrate Vasodilator, Endogenous
Nitric Oxide, Endothelium Derived
 
Nitric Oxide, Endothelium-Derived
Nitric oxide
Nitric oxide (JAN)
Nitric oxide 10% by volume or more
Nitric oxide trimer
Nitric oxide, compressed [UN1660] [Poison gas]
Nitric oxide, compressed [UN1660] [Poison gas]
Nitrogen monoxide
Nitrogen oxide
Nitrogen oxide (NO)
Nitrogen protoxide
Nitrosyl
Nitrosyl hydride
Nitrosyl hydride ((NO)H)
Nitrosyl radical
Nitroxide radical
Nitroxyl
OHM 11771
Oxide, Nitric
Oxido de nitrogeno(ii)
Oxido nitrico
Oxyde azotique
Oxyde nitrique
Oxyde nitrique [French]
RCRA waste no. P076
Stickmonoxyd
Stickmonoxyd [German]
Stickstoff(II)-oxid
Stickstoff(ii)-oxid
Stickstoffmonoxid
UN 1660
UN1660
UNII-31C4KY9ESH
Vasodilator, Endogenous Nitrate
[NO]
endothelium-derived relaxing factor
monoxido de nitrogeno
monoxyde d'azote
nitric oxide
nitrogen monooxide
nitrogen monoxide
nitrosyl
oxido de nitrogeno(II)
oxido nitrico
oxidonitrogen(.)
oxoazanyl
oxyde azotique
6
Oxytocinapproved33550-56-6439302, 53477758
Synonyms:
(2S)-1-[(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
(Arg8)-Vasopressin
(Arg8)-Vasotocin
1-({(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-16-(4-hydroxybenzyl)-13-[(1S)-1-methylpropyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl}carbonyl)-L-prolyl-L-leucylglycinamide
50-56-6
AC1L9735
Argipressin
Argpressin Acetate
BCBcMAP01_000094
Biotinyl-(Arg8)-Vasopressin
C00746
CHEBI:492195
CHEBI:7872
CHEMBL395429
CID439302
Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Arg-Gly-NH2
Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2
Cys-Tyr-Ile-Thr-Asn-Cys-Gly-Leu-Gly-NH2
Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH2
Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH2
D00089
Disulfide bridge Cys1-Cys6
Gly-Leu-Pro-c
HS-2021
L-Cysteinyl-L-tyrosyl-L-isoleucyl-L-glutaminyl-L-asparaginyl-L-cysteinyl-L-prolyl-L-leucylglycinamide cyclic(1-6)-disulfide
MolPort-003-938-941
 
NCGC00167132-01
O3251_SIGMA
O4375_SIGMA
OXT
OXYTOCIN
Ocytocin
Oxitocina
Oxytocic hormone
Oxytocin
Oxytocin (JP15/USP/INN)
Oxytocin (TN)
Oxytocin 10 Usp Units In Dextrose 5%
Oxytocin 20 Usp Units In Dextrose 5%
Oxytocin 5 Usp Units In Dextrose 5%
Oxytocin Acetate
Oxytocin injection
Oxytocine
Oxytocinum
Pitocin
Pitocin (TN)
SID29217903
SID50111741
Syntocinon
Syntocinon (TN)
TI-001
alpha-Hypophamine
nchembio.184-comp2
7
Dinoprostoneapproved67363-24-65280360
Synonyms:
(-)-Prostaglandin E2
(15S)-Prostaglandin E2
(15S)-Prostaglandin e2
(5Z,11-alpha,13E,15S)-11,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oic acid
(5Z,11.alpha.,13E,15S)-11,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oic acid
(5Z,11alpha,13E,15S)-11,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oic
(5Z,11alpha,13E,15S)-11,15-Dihydroxy-9-oxoprosta-5,13-dienoic acid
(5Z,11alpha,13E,15S)-11,15-dihydroxy-9-oxoprosta-5,13-dien-1-oic acid
(5Z,11alpha,13e,15S)-11,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oic acid
(5Z,13E)-(15S)-11alpha,15-Dihydroxy-9-oxoprost-13-enoate
(5Z,13E)-(15S)-11alpha,15-Dihydroxy-9-oxoprost-13-enoic acid
(5Z,13E)-(15S)-11alpha,15-Dihydroxy-9-oxoprosta-5,13-dienoate
(5Z,13E)-(15S)-11alpha,15-Dihydroxy-9-oxoprosta-5,13-dienoic acid
(5Z,13E)-(15S)-11alpha,15-dihydroxy-9-oxoprosta-5,13-dienoate
(5Z,13E,15S)-11-alpha,15-dihydroxy-9-oxoprost-5,13-dienoate
(5Z,13E,15S)-11-alpha,15-dihydroxy-9-oxoprost-5,13-dienoic acid
(5Z,13E,15S)-11alpha,15-dihydroxy-9-oxoprosta-5,13-dien-1-oic acid
(5Z,13e)-(15S)-11alpha,15-Dihydroxy-9-oxoprost-13-enoate
(5Z,13e)-(15S)-11alpha,15-Dihydroxy-9-oxoprosta-5,13-dienoate
(E,Z)-(1R,2R,3R)-7-(3-Hydroxy-2-((3S)-(3-hydroxy-1-octenyl))-5-oxocyclopentyl)-5-heptenoic acid
(Z)-7-((1R,2R,3R)-3-Hydroxy-2-((S,e)-3-hydroxyoct-1-enyl)-5-oxocyclopentyl)hept-5-enoic acid
(Z)-7-[(1R,2R,3R)-3-Hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxocyclopentyl]hept-5-enoic acid
(e,Z)-(1R,2R,3R)-7-(3-Hydroxy-2-((3S)-(3-hydroxy-1-octenyl))-5-oxocyclopentyl)-5-heptenoic acid
05D31BD5-818B-4A92-8CFC-BEC19926A5B3
363-24-6
5-Heptenoic acid, 7-(3-hydroxy-2-(3-hydroxy-1-octenyl)-5-oxocyclopentyl)- (8CI)
5-trans-PGE2
7-(3-Hydroxy-2-(3-hydroxy-1-octenyl)-5-oxocyclopentyl)-5-heptenoic acid
AC-6098
AC1NQWXW
BML1-F07
BMS-279654 & PGE2
BRD-K26521938-001-04-9
BSPBio_001490
C00584
CHEBI:15551
CHEMBL548
CID5280360
Cervidil
Cervidil (TN)
D00079
D015232
DB00917
Dinoproston
Dinoprostona
Dinoprostona [INN-Spanish]
Dinoprostone
Dinoprostone (JAN/USP/INN)
Dinoprostone Prostaglandin E2
Dinoprostone [USAN:INN:BAN:JAN]
Dinoprostone beta-Cyclodextrin Clathrate
Dinoprostonum
Dinoprostonum [INN-Latin]
E2 alpha, Prostaglandin
E2, Prostaglandin
E2alpha, Prostaglandin
 
EINECS 206-656-6
Gel, Prepidil
Glandin
HMS1361K12
HMS1791K12
HMS1989K12
HMS2089D17
IDI1_033960
L-Prostaglandin E2
LMFA03010003
LS-125823
Minprositin E2
Minprostin E2
MolPort-003-939-184
NCGC00092361-01
NCGC00092361-02
NCGC00092361-03
NCGC00092361-04
NCGC00092361-05
NSC 165560
NSC 196514
P0409_SIGMA
P5640_SIGMA
P6532_SIGMA
PGE2
PGE2 alpha
PGE2alpha
Prepidil
Prepidil (TN)
Prepidil Gel
Prestwick_793
Propess
Prostaglandin E
Prostaglandin E2
Prostaglandin E2 alpha
Prostaglandin E2alpha
Prostarmon E
Prostarmon E2
Prostenon
Prostin
Prostin E
Prostin E2
Prostin E2 (TN)
Prostin e2
SMP2_000056
ST50826265
U 12062
U-12062
UNII-K7Q1JQR04M
[3H]PGE2
alpha, PGE2
alpha, Prostaglandin E2
l-7-(3-Hydroxy-2-(3-hydroxy-1-octenyl)-5-oxocyclopentyl)-5-heptenoic acid
l-PGE2
l-Prostaglandin E2
nchembio.106-comp6
nchembio.147-comp12
8
Misoprostolapproved24459122-46-25282381
Synonyms:
(+/-)-15-Deoxy-(16RS)-16-hydroxy-16-methylprostaglandin E1 methyl ester
(11-alpha,13E)-(+-)-11,16-Dihydroxy-16-methyl-9-oxoprost-13-en-1-oic acid methyl ester
59122-46-2
62015-39-8
AC1NQZZA
Ambap103601-27-0
Arthrotec
BRN 4155643
CCRIS 6859
CHEMBL606
CID5282381
Cytotec
Cytotec (TN)
D00419
DB00929
GyMiso
HMS2090L10
HSDB 3573
I14-11712
Isprelor
 
M6807_SIGMA
MLS000028863
Methyl (+-)-11-alpha,16-dihydroxy-16-methyl-9-oxoprost-13-en-1-oate
Misopess
Misoprostol
Misoprostol (JAN/USAN/INN)
Misoprostolum
Misoprostolum [INN-Latin]
Misotol
MolPort-003-666-830
NCGC00162445-01
NCGC00162445-02
SC 29333
SC-29333
SMP1_000193
SMR000058558
UNII-0E43V0BB57
XP-16J
methyl (11alpha,13E)-11,16-dihydroxy-16-methyl-9-oxoprost-13-en-1-oate
methyl 7-[(1R,2R,3R)-3-hydroxy-2-[(E)-4-hydroxy-4-methyloct-1-enyl]-5-oxocyclopentyl]heptanoate
misoprostol

Interventional clinical trials:

(show all 19)
idNameStatusNCT IDPhase
1Oral Sildenafil in Persistent Pulmonary Hypertension Secondary to Meconium Aspiration Syndrome in NewbornsCompletedNCT01757782Phase 4
2Lung Lavage With Dilute Poractant Alfa for Meconium Aspiration SyndromeRecruitingNCT02041546Phase 4
3Cervical Ripening for Obese Women: A Randomized, Comparative Effectiveness TrialRecruitingNCT02639429Phase 4
4Surfactant Lavage vs. Bolus Surfactant in Neonates With Meconium AspirationRecruitingNCT00312507Phase 3
5Phase III Randomized Study of Lucinactant in Full Term Newborn Infants With Meconium Aspiration SyndromeTerminatedNCT00004500Phase 3
6Inhaled Nitric Oxide Study for Respiratory Failure in NewbornsTerminatedNCT00005776Phase 3
7Early Inhaled Nitric Oxide for Respiratory Failure in NewbornsTerminatedNCT00005773Phase 3
8Inhaled PGE1 in Neonatal Hypoxemic Respiratory FailureWithdrawnNCT00598429Phase 2
9Effect Of Intrapartum Oropharyngeal (IP-OP) Suction on Meconium Aspiration SyndromeCompletedNCT01328483
10Comparison Of Surfactant Lung Lavage With Standard Care In The Treatment Of Meconium Aspiration SyndromeCompletedNCT01310621
11Use of Heliox in the Management of Neonates With Meconium Aspiration SyndromeCompletedNCT01274845
12Role of Endotracheal Suction on the Occurrence of Meconium Aspiration Syndrome in Non-vigorous Meconium Stained BabiesCompletedNCT01758822
13Antibody Secreting Cell and Cyotokine Profiles in Neonates on ECMOCompletedNCT00371241
14Post Term Pregnancy - Induction of Labor or Monitoring of PregnancyCompletedNCT00385229
15Effect of Gastric Lavage in Preventing Feeding Problems in Babies Born With Meconium Stained Amniotic FluidCompletedNCT01306500
16Helium Oxygen Mixture in the Treatment of Meconium Aspiration SyndromeRecruitingNCT02620891
17Role and Molecular Mechanism of Farnesoid X Receptor(FXR) and RIPK3 in the Formation of Acute Respiratory Distress Syndrome in NeonatesRecruitingNCT02598648
18High Flow Ventilation With Volume GuaranteeNot yet recruitingNCT02571231
19Efficacy and Safety of Gastric Suctioning During Neonatal ResuscitationNot yet recruitingNCT00729989

Search NIH Clinical Center for Meconium Aspiration Syndrome


Cochrane evidence based reviews: Meconium Aspiration Syndrome

Genetic Tests for Meconium Aspiration Syndrome

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Anatomical Context for Meconium Aspiration Syndrome

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MalaCards organs/tissues related to Meconium Aspiration Syndrome:

33
Lung, Uterus

Animal Models for Meconium Aspiration Syndrome or affiliated genes

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MGI Mouse Phenotypes related to Meconium Aspiration Syndrome:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053678.4CSF2, EDN1, IFNG, IL6, SCGB1A1
2MP:00020067.6CSF2, IFNG, IL6, SCGB1A1, TNF
3MP:00053797.4CSF2, EDN1, IFNG, IL6, SCGB1A1, TNF
4MP:00053887.3CSF2, IFNG, IL6, SCGB1A1, SFTPB, TNF
5MP:00107686.5CPS1, CSF2, EDN1, IFNG, IL6, SCGB1A1
6MP:00053766.1CPS1, CSF2, EDN1, IFNG, IL6, SCGB1A1

Publications for Meconium Aspiration Syndrome

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Articles related to Meconium Aspiration Syndrome:

(show top 50)    (show all 276)
idTitleAuthorsYear
1
Histologic Evidence of Intrapulmonary Bronchopulmonary Anastomotic Pathways in Neonates with Meconium Aspiration Syndrome. (26421487)
2015
2
Risk factors differentiating mild/moderate from severe meconium aspiration syndrome in meconium-stained neonates. (25629015)
2015
3
To study prevalence of persistent pulmonary hypertension in newborn with meconium aspiration syndrome in western Rajasthan, India: a prospective observational study. (25586320)
2015
4
Lung lavage in meconium aspiration syndrome. (23662695)
2013
5
A Population-Based Study of Meconium Aspiration Syndrome in Neonates Born between 37 and 43 Weeks of Gestation. (22187569)
2012
6
Surfactant lavage therapy for meconium aspiration syndrome: a systematic review and meta-analysis. (22067375)
2012
7
Respiratory support in meconium aspiration syndrome: a practical guide. (22518190)
2012
8
Comparative effects of bronchoalveolar lavage with saline, surfactant, or perfluorocarbon in experimental meconium aspiration syndrome. (22079955)
2012
9
Use of heliox in the management of neonates with meconium aspiration syndrome. (21701217)
2011
10
Trends in obstetric practices and meconium aspiration syndrome: a population-based study. (21895951)
2011
11
Intratracheal catheter suction removes the same volume of meconium with less impact on desaturation compared with meconium aspirator in meconium aspiration syndrome. (20634007)
2010
12
Effective lavage volume of diluted surfactant improves the outcome of meconium aspiration syndrome in newborn piglets. (19287342)
2009
13
Prevention of meconium aspiration syndrome: an update and the Baylor experience. (19381312)
2009
14
Role of meconium in the reaction of airways smooth musculature in the newborn with meconium aspiration syndrome (MAS). (20002002)
2009
15
Introduction: Proceedings of the First International Conference for Meconium Aspiration Syndrome and Meconium-induced Lung Injury. (19057597)
2008
16
Effects of a recombinant surfactant protein-C-based surfactant on lung function and the pulmonary surfactant system in a model of meconium aspiration syndrome. (16374175)
2006
17
Meconium aspiration syndrome--more than intrapartum meconium. (16135842)
2005
18
Treatment of experimental meconium aspiration syndrome with surfactant lung lavage and conventional vs. asymmetric high-frequency jet ventilation. (15334504)
2004
19
Meconium-stained amniotic fluid, meconium aspiration syndrome, and persistent pulmonary hypertension of the newborn. (15624362)
2004
20
Steroid therapy for meconium aspiration syndrome in newborn infants. (14583981)
2003
21
Meconium aspiration syndrome: is surfactant lavage the answer? (12912732)
2003
22
Racial disparity in meconium-stained amniotic fluid and meconium aspiration syndrome in the United States, 1989-2000. (14662213)
2003
23
Meconium aspiration syndrome: a role for phospholipase A2 in the pathogenesis? (11332922)
2001
24
Risk factors for meconium aspiration syndrome in infants born through thick meconium. (11146071)
2001
25
Meconium aspiration syndrome in term neonates with normal acid-base status at delivery: is it different? (11408862)
2001
26
Combined effects of high-frequency ventilation and surfactant treatment in experimental meconium aspiration syndrome. (10027019)
1999
27
Bronchoalveolar lavage with KL4-surfactant in models of meconium aspiration syndrome. (9803452)
1998
28
Antenatal risk factors and neonatal outcome in meconium aspiration syndrome. (12348097)
1997
29
Meconium aspiration syndrome: current concepts. (12320376)
1996
30
Surfactant replacement therapy for meconium aspiration syndrome. (8545223)
1996
31
Lung lavage with a saline volume similar to functional residual capacity followed by surfactant administration in newborns with severe meconium aspiration syndrome. (8986496)
1996
32
Meconium aspiration syndrome: diagnosis and care guidelines. (7787904)
1995
33
Risk factors for meconium aspiration syndrome. (7617354)
1995
34
Meconium aspiration syndrome. (7862068)
1994
35
Surfactant therapy and high-frequency jet ventilation in the management of a piglet model of the meconium aspiration syndrome. (7816525)
1994
36
Meconium aspiration syndrome: physiological and inflammatory changes in a newborn piglet model. (8367215)
1993
37
Meconium aspiration syndrome: have we made a difference? (2330231)
1990
38
Meconium aspiration syndrome without evidence of fetal distress in early labor before elective cesarean delivery. (2704495)
1989
39
Extracorporeal membrane oxygenation as treatment of severe meconium aspiration syndrome. (2734633)
1989
40
Failure to prevent meconium aspiration syndrome. (3347418)
1988
41
Fatal meconium aspiration syndrome occurring despite airway management considered appropriate. (3976781)
1985
42
The relationship of thrombocytopenia to the onset of persistent pulmonary hypertension of the newborn in the meconium aspiration syndrome. (3860753)
1985
43
Experimental meconium aspiration syndrome in the preterm fetal lamb: successful treatment using the extracorporeal artificial lung. (6424302)
1983
44
Intrauterine meconium aspiration syndrome. (7439009)
1980
45
Technical aspects in the management of the meconium aspiration syndrome with extracorporeal circulation. (7411345)
1980
46
Roentgenographic findings in infants with meconium aspiration syndrome. (448867)
1979
47
Prevention of meconium aspiration syndrome in newborn infants. (660325)
1978
48
The effect of tolazoline on right-to-left shunting via a patent ductus arteriosus in meconium aspiration syndrome. (803084)
1976
49
Assisted ventilation in infants with meconium aspiration syndrome. (240148)
1975
50
Wilson-Mikity or meconium aspiration syndrome? (4695868)
1973

Variations for Meconium Aspiration Syndrome

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Expression for genes affiliated with Meconium Aspiration Syndrome

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Search GEO for disease gene expression data for Meconium Aspiration Syndrome.

Pathways for genes affiliated with Meconium Aspiration Syndrome

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Pathways related to Meconium Aspiration Syndrome according to GeneCards Suite gene sharing:

(show all 41)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.8EDN1, SCGB1A1
29.7CXCL8, IL6
39.6CSF2, CXCL8
49.3CXCL8, TNF
59.2IL6, TNF
69.2CSF2, CXCL8, IL6
7
Show member pathways
9.2CSF2, CXCL8, IL6
89.1EDN1, IFNG, IL6
99.1CXCL8, IFNG, IL6
109.1CXCL8, IFNG, IL6
11
Show member pathways
8.9CSF2, IFNG, IL6
12
Show member pathways
8.9CXCL8, IL6, TNF
138.9CXCL8, IL6, TNF
148.9CXCL8, IL6, TNF
158.9CXCL8, IL6, TNF
168.7CSF2, IL6, TNF
178.6IFNG, IL6, TNF
188.6IFNG, IL6, TNF
198.6IFNG, IL6, TNF
208.6IFNG, IL6, TNF
21
Show member pathways
8.6IFNG, IL6, TNF
22
Show member pathways
8.6IFNG, IL6, TNF
23
Show member pathways
8.6CXCL8, EDN1, IL6, TNF
248.6CSF2, CXCL8, IFNG, IL6
25
Salmonella infection (KEGG)
Show member pathways
8.6CSF2, CXCL8, IFNG, IL6
26
Show member pathways
8.5CSF2, IFNG, TNF
278.4CSF2, EDN1, IL6, TNF
288.3CXCL8, IFNG, IL6, TNF
298.3CXCL8, IFNG, IL6, TNF
30
Show member pathways
8.3CXCL8, IFNG, IL6, TNF
318.3CXCL8, IFNG, IL6, TNF
32
Show member pathways
8.3CXCL8, IFNG, IL6, TNF
33
Show member pathways
8.3CXCL8, IFNG, IL6, TNF
34
Show member pathways
8.3CXCL8, IFNG, IL6, TNF
35
Show member pathways
8.3CXCL8, IFNG, IL6, TNF
36
Show member pathways
8.2CSF2, CXCL8, IFNG, TNF
378.1CSF2, IFNG, IL6, TNF
38
B cell receptor signaling pathway (KEGG)
Show member pathways
8.1CSF2, IFNG, IL6, TNF
397.8CSF2, CXCL8, IFNG, IL6, TNF
407.8CSF2, CXCL8, IFNG, IL6, TNF
41
Show member pathways
7.4CSF2, CXCL8, EDN1, IFNG, IL6, TNF

GO Terms for genes affiliated with Meconium Aspiration Syndrome

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Cellular components related to Meconium Aspiration Syndrome according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1external side of plasma membraneGO:00098979.1IFNG, IL6, TNF
2extracellular regionGO:00055766.7CSF2, CXCL8, EDN1, IFNG, IL6, SFTPB
3extracellular spaceGO:00056156.6CSF2, CXCL8, EDN1, IFNG, IL6, SCGB1A1

Biological processes related to Meconium Aspiration Syndrome according to GeneCards Suite gene sharing:

(show all 40)
idNameGO IDScoreTop Affiliating Genes
1negative regulation of hormone secretionGO:004688810.4EDN1, IL6
2epithelial fluid transportGO:004204510.3CSF2, EDN1
3neutrophil apoptotic processGO:000178110.2IFNG, IL6
4response to ozoneGO:001019310.2EDN1, SCGB1A1
5positive regulation of neutrophil chemotaxisGO:009002310.2CXCL8, EDN1
6respiratory gaseous exchangeGO:000758510.1EDN1, SFTPB
7response to dexamethasoneGO:007154810.1CPS1, EDN1
8positive regulation of interleukin-23 productionGO:003274710.0CSF2, IFNG
9defense response to protozoanGO:004283210.0IFNG, IL6
10positive regulation of JUN kinase activityGO:00435079.9EDN1, TNF
11epithelial cell proliferation involved in salivary gland morphogenesisGO:00606649.9IL6, TNF
12negative regulation of lipid storageGO:00108889.9IL6, TNF
13positive regulation of chemokine productionGO:00327229.9IL6, TNF
14positive regulation of DNA replicationGO:00457409.8CSF2, IL6
15cellular response to interleukin-1GO:00713479.8CXCL8, EDN1, IL6
16positive regulation of vitamin D biosynthetic processGO:00605579.8IFNG, TNF
17cellular response to tumor necrosis factorGO:00713569.8CXCL8, EDN1, IL6
18positive regulation of podosome assemblyGO:00718039.7CSF2, TNF
19positive regulation of calcidiol 1-monooxygenase activityGO:00605599.7IFNG, TNF
20response to amino acidGO:00432009.7CPS1, EDN1, IL6
21embryonic digestive tract developmentGO:00485669.7CXCL8, TNF
22cellular response to fibroblast growth factor stimulusGO:00443449.7CPS1, CXCL8
23positive regulation of chemokine biosynthetic processGO:00450809.7IFNG, TNF
24positive regulation of membrane protein ectodomain proteolysisGO:00510449.7IFNG, TNF
25protein import into nucleus, translocationGO:00000609.7IFNG, TNF
26negative regulation of growth of symbiont in hostGO:00441309.5IFNG, TNF
27neutrophil chemotaxisGO:00305939.5CXCL8, EDN1, IFNG
28positive regulation of osteoclast differentiationGO:00456729.5IFNG, TNF
29positive regulation of smooth muscle cell proliferationGO:00486619.3EDN1, IL6, TNF
30response to lipopolysaccharideGO:00324969.3CPS1, EDN1, IL6, SCGB1A1
31humoral immune responseGO:00069599.2IFNG, IL6, TNF
32negative regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:20012409.1CSF2, TNF
33regulation of cell proliferationGO:00421278.8CSF2, IL6, TNF
34response to glucocorticoidGO:00513848.8CPS1, IL6, SCGB1A1, TNF
35positive regulation of cell proliferationGO:00082848.8CSF2, EDN1, IFNG, IL6
36positive regulation of nitric oxide biosynthetic processGO:00454298.6EDN1, IFNG, IL6, TNF
37cellular response to lipopolysaccharideGO:00712228.1CSF2, CXCL8, IFNG, IL6, TNF
38immune responseGO:00069558.1CSF2, CXCL8, IFNG, IL6, TNF
39positive regulation of gene expressionGO:00106288.0CSF2, IFNG, IL6, TNF
40response to drugGO:00424937.9CPS1, EDN1, IFNG, IL6, SCGB1A1

Molecular functions related to Meconium Aspiration Syndrome according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1cytokine activityGO:00051257.8CSF2, EDN1, IFNG, IL6, TNF

Sources for Meconium Aspiration Syndrome

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet