MCID: MCN007
MIFTS: 51

Meconium Aspiration Syndrome malady

Categories: Rare diseases, Fetal diseases, Respiratory diseases

Aliases & Classifications for Meconium Aspiration Syndrome

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Sources:
11Disease Ontology, 13DISEASES, 30ICD10, 31ICD10 via Orphanet, 39MeSH, 40MESH via Orphanet, 45NCIt, 48NIH Rare Diseases, 50Novoseek, 54Orphanet, 62SNOMED-CT, 68UMLS, 69UMLS via Orphanet
See all MalaCards sources

Aliases & Descriptions for Meconium Aspiration Syndrome:

Name: Meconium Aspiration Syndrome 11 48 54 50 39 13 68
Neonatal Aspiration of Meconium 11
Macrophage Activation Syndrome 68
 
Meconium Aspiration 11
Mas 48

Characteristics:

Orphanet epidemiological data:

54
meconium aspiration syndrome:
Inheritance: Not applicable; Prevalence: 1-9/100000 (Europe); Age of onset: Infancy,Neonatal

Classifications:



External Ids:

Disease Ontology11 DOID:11049
MeSH39 D008471
NCIt45 C87093
Orphanet54 ORPHA70588
MESH via Orphanet40 D008471
UMLS via Orphanet69 C0025048
ICD10 via Orphanet31 P24.0

Summaries for Meconium Aspiration Syndrome

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NIH Rare Diseases:48 Meconium aspiration syndrome is a serious condition in which a newborn breathes a mixture of meconium and amniotic fluid into the lungs around the time of delivery. This can cause breathing difficulties due to swelling (inflammation) in the baby's lungs after birth. Treatment may include suctioning the newborn's mouth as soon as the head emerges during delivery, deep suctioning of the windpipe, antibiotics to treat infection, oxygen to keep blood levels normal, and radiant heat to maintain body temperature. In severe cases, the baby may need assistance breathing (ventilator). Last updated: 1/12/2012

MalaCards based summary: Meconium Aspiration Syndrome, also known as neonatal aspiration of meconium, is related to asthma and pulmonary hypertension, neonatal, and has symptoms including cheyne-stokes respiration, coughing and dyspnea. An important gene associated with Meconium Aspiration Syndrome is EDN1 (Endothelin 1), and among its related pathways are Prostaglandin Synthesis and Regulation and EBV LMP1 signaling. Affiliated tissues include lung and uterus, and related mouse phenotypes are Increased cell death in breast cancer cell lines (MCF10A, MDA-MB-435) and renal/urinary system.

Wikipedia:71 Meconium aspiration syndrome (MAS) also known as neonatal aspiration of meconium is a medical condition... more...

Related Diseases for Meconium Aspiration Syndrome

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Diseases related to Meconium Aspiration Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 260)
idRelated DiseaseScoreTop Affiliating Genes
1asthma26.8CSF2, CXCL8, EDN1, IFNG, IL6, SCGB1A1
2pulmonary hypertension, neonatal11.1
3basidiobolomycosis10.5CXCL8, TNF
43-alpha hydroxyacyl-coa dehydrogenase deficiency10.5CXCL8, TNF
5corneal deposit10.5CXCL8, IL6
6tarsal tunnel syndrome10.5CXCL8, IL6
7t-cell lymphoma 1a10.5CXCL8, TNF
8anterior dislocation of lens10.5CXCL8, IL6
9retinal vascular disease10.5CXCL8, IL6
10infancy electroclinical syndrome10.4CXCL8, IL6
11paraphimosis10.4CXCL8, TNF
12autosomal dominant cerebellar ataxia10.4CXCL8, IL6
13mycobacterium fortuitum10.4CXCL8, TNF
14subglottis neoplasm10.4CXCL8, IL6
15aortic arch interruption10.4IL6, TNF
16uhl anomaly10.4SCGB1A1, SFTPB
17osteogenesis imperfecta, type x10.4CXCL8, IL6
18hemometra10.4IL6, TNF
19tricho odonto onycho dermal syndrome10.4IL6, TNF
20scrotum paget's disease10.4IL6, TNF
21oropharynx cancer10.4CXCL8, TNF
22gasserian ganglion meningioma10.4CXCL8, IL6
23epstein-barr virus hepatitis10.4IL6, TNF
24abdominal chemodectomas with cutaneous angiolipomas10.4IL6, TNF
25antigen-peptide-transporter 2 deficiency10.4IL6, TNF
26dysgerminoma of ovary10.4SCGB1A1, SFTPB
27inflammatory spondylopathy10.4CXCL8, IL6
28neurofibroma of the esophagus10.4CXCL8, IL6
29hypothyroidism10.4IL6, TNF
30ethmoid sinus adenoid cystic carcinoma10.4IL6, TNF
31autoimmune polyendocrine syndrome10.4IL6, TNF
32ocular cancer10.4CXCL8, IL6
33splenic manifestation of prolymphocytic leukemia10.4IL6, TNF
34post-infectious myocarditis10.4IL6, TNF
35scarlet fever10.4IL6, TNF
36non-secretory myeloma10.4IL6, TNF
37baetz-greenwalt syndrome10.4IFNG, TNF
38autoimmune pancreatitis10.4IFNG, TNF
39tonsillar fossa cancer10.4CXCL8, IL6
40atypical depressive disorder10.4IL6, TNF
41graft-versus-host disease, protection against10.3IFNG, TNF
42uterine corpus endometrial stromal sarcoma10.3CXCL8, TNF
43gonococcal synovitis10.3IFNG, TNF
44sterility due to immotile flagella10.3IL6, TNF
45islet cell tumor10.3IL6, TNF
46cauda equina syndrome10.3IL6, TNF
47inner ear cancer10.3CXCL8, TNF
48scrotum melanoma10.3CXCL8, IL6
49lymphangiectasia, intestinal10.3CSF2, CXCL8
50primary orthostatic tremor10.3IFNG, TNF

Graphical network of the top 20 diseases related to Meconium Aspiration Syndrome:



Diseases related to meconium aspiration syndrome

Symptoms & Phenotypes for Meconium Aspiration Syndrome

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UMLS symptoms related to Meconium Aspiration Syndrome:


cheyne-stokes respiration, coughing, dyspnea, hemoptysis, hoarseness, gasping syndrome

GenomeRNAi Phenotypes related to Meconium Aspiration Syndrome according to GeneCards Suite gene sharing:

26
idDescriptionGenomeRNAi Source AccessionScoreTop Affiliating Genes
1GR00104-A-010.0CSF2, CXCL8, TNF

MGI Mouse Phenotypes related to Meconium Aspiration Syndrome according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053678.7CSF2, EDN1, IFNG, IL6, SCGB1A1
2MP:00020068.6CSF2, IFNG, IL6, SCGB1A1, TNF
3MP:00053798.4CSF2, EDN1, IFNG, IL6, SCGB1A1, TNF
4MP:00053887.4CSF2, IFNG, IL6, SCGB1A1, SFTPB, TNF
5MP:00053767.2CPS1, CSF2, EDN1, IFNG, IL6, SCGB1A1
6MP:00107687.2CPS1, CSF2, EDN1, IFNG, IL6, SCGB1A1

Drugs & Therapeutics for Meconium Aspiration Syndrome

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Drugs for Meconium Aspiration Syndrome (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 29)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1Poractant alfaapprovedPhase 425129069-19-8
2
MisoprostolapprovedPhase 428659122-46-25282381
Synonyms:
(+/-)-15-Deoxy-(16RS)-16-hydroxy-16-methylprostaglandin E1 methyl ester
(11-alpha,13E)-(+-)-11,16-Dihydroxy-16-methyl-9-oxoprost-13-en-1-oic acid methyl ester
59122-46-2
62015-39-8
AC1NQZZA
Ambap103601-27-0
BRN 4155643
CCRIS 6859
CHEMBL606
CID5282381
Cytotec
Cytotec (TN)
D00419
DB00929
GyMiso
HMS2090L10
HSDB 3573
I14-11712
Isprelor
 
M6807_SIGMA
MLS000028863
Methyl (+-)-11-alpha,16-dihydroxy-16-methyl-9-oxoprost-13-en-1-oate
Misopess
Misoprostol (JAN/USAN/INN)
Misoprostolum
Misoprostolum [INN-Latin]
Misotol
MolPort-003-666-830
NCGC00162445-01
NCGC00162445-02
SC 29333
SC-29333
SMP1_000193
SMR000058558
UNII-0E43V0BB57
XP-16J
methyl (11alpha,13E)-11,16-dihydroxy-16-methyl-9-oxoprost-13-en-1-oate
methyl 7-[(1R,2R,3R)-3-hydroxy-2-[(E)-4-hydroxy-4-methyloct-1-enyl]-5-oxocyclopentyl]heptanoate
misoprostol
3Pulmonary SurfactantsPhase 4, Phase 3107
4Respiratory System AgentsPhase 4, Phase 34818
5Vasodilator AgentsPhase 4, Phase 3, Phase 23438
6Sildenafil CitratePhase 4323171599-83-0
7Pharmaceutical SolutionsPhase 47793
8Phosphodiesterase 5 InhibitorsPhase 4571
9Phosphodiesterase InhibitorsPhase 41254
10Gastrointestinal AgentsPhase 48109
11Anti-Ulcer AgentsPhase 41767
12OxytocicsPhase 4660
13AntacidsPhase 41767
14CitrateNutraceuticalPhase 41106
15
Citric Acidnutraceutical, vet_approvedPhase 4110677-92-9311
Synonyms:
2-Hydroxy-1,2,3-propanetricarboxylate
2-Hydroxy-1,2,3-propanetricarboxylic acid
2-Hydroxytricarballylic acid
3-Carboxy-3-hydroxypentane-1,5-dioate
3-Carboxy-3-hydroxypentane-1,5-dioic acid
Aciletten
Anhydrous citrate
Anhydrous citric acid
Chemfill
Citraclean
 
Citrate
Citretten
Citric acid
Citro
Citronensäure
E 330
Hydrocerol A
Kyselina citronova
Suby G
Uro-trainer
beta-Hydroxytricarballylate
beta-Hydroxytricarballylic acid
16
Nitric OxideapprovedPhase 359910102-43-9145068
Synonyms:
(.)NO
(NO)(.)
10102-43-9
14332-28-6
295566_ALDRICH
51005-20-0
51005-21-1
53851-19-7
90452-29-2
AC1L1ADQ
AC1L3QHF
AC1Q6QZ0
AR-1K7463
Bioxyde d'azote
Bioxyde d'azote [French]
C00533
CCRIS 4319
CHEMBL1200689
CHEMBL1234765
CID145068
CID945
D00074
D009569
DB00435
EDRF
EINECS 233-271-0
Endogenous Nitrate Vasodilator
Endothelium-Derived Nitric Oxide
HNO
HSDB 1246
INOmax
INOmax (TN)
LS-192158
LS-7547
MolPort-003-929-452
Mononitrogen monoxide
Monoxide, Mononitrogen
Monoxide, Nitrogen
Monoxido de nitrogeno
Monoxyde d'azote
NITRIC-OXIDE
NO
NO(.)
Nitrate Vasodilator, Endogenous
Nitric Oxide, Endothelium Derived
 
Nitric Oxide, Endothelium-Derived
Nitric oxide
Nitric oxide (JAN)
Nitric oxide 10% by volume or more
Nitric oxide trimer
Nitric oxide, compressed [UN1660] [Poison gas]
Nitric oxide, compressed [UN1660] [Poison gas]
Nitrogen monoxide
Nitrogen oxide
Nitrogen oxide (NO)
Nitrogen protoxide
Nitrosyl
Nitrosyl hydride
Nitrosyl hydride ((NO)H)
Nitrosyl radical
Nitroxide radical
Nitroxyl
OHM 11771
Oxide, Nitric
Oxido de nitrogeno(ii)
Oxido nitrico
Oxyde azotique
Oxyde nitrique
Oxyde nitrique [French]
RCRA waste no. P076
Stickmonoxyd
Stickmonoxyd [German]
Stickstoff(II)-oxid
Stickstoff(ii)-oxid
Stickstoffmonoxid
UN 1660
UN1660
UNII-31C4KY9ESH
Vasodilator, Endogenous Nitrate
[NO]
endothelium-derived relaxing factor
monoxido de nitrogeno
monoxyde d'azote
nitric oxide
nitrogen monooxide
nitrogen monoxide
nitrosyl
oxido de nitrogeno(II)
oxido nitrico
oxidonitrogen(.)
oxoazanyl
oxyde azotique
17Endothelium-Dependent Relaxing FactorsPhase 3272
18Neurotransmitter AgentsPhase 317734
19Peripheral Nervous System AgentsPhase 322776
20Protective AgentsPhase 37190
21Bronchodilator AgentsPhase 32856
22Autonomic AgentsPhase 39774
23Anti-Asthmatic AgentsPhase 33369
24Vasoconstrictor AgentsPhase 32027
25AntioxidantsPhase 32928
26
Oxytocinapproved, vet_approved40850-56-6439302, 53477758
Synonyms:
(2S)-1-[(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
(Arg8)-Vasopressin
(Arg8)-Vasotocin
1-({(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-16-(4-hydroxybenzyl)-13-[(1S)-1-methylpropyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl}carbonyl)-L-prolyl-L-leucylglycinamide
50-56-6
AC1L9735
Argipressin
Argpressin Acetate
BCBcMAP01_000094
Biotinyl-(Arg8)-Vasopressin
C00746
CHEBI:492195
CHEBI:7872
CHEMBL395429
CID439302
Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Arg-Gly-NH2
Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2
Cys-Tyr-Ile-Thr-Asn-Cys-Gly-Leu-Gly-NH2
Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH2
Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH2
D00089
Disulfide bridge Cys1-Cys6
Gly-Leu-Pro-c
HS-2021
 
L-Cysteinyl-L-tyrosyl-L-isoleucyl-L-glutaminyl-L-asparaginyl-L-cysteinyl-L-prolyl-L-leucylglycinamide cyclic(1-6)-disulfide
MolPort-003-938-941
NCGC00167132-01
O3251_SIGMA
O4375_SIGMA
OXT
OXYTOCIN
Ocytocin
Oxitocina
Oxytocic hormone
Oxytocin (JP15/USP/INN)
Oxytocin (TN)
Oxytocin 10 Usp Units In Dextrose 5%
Oxytocin 20 Usp Units In Dextrose 5%
Oxytocin 5 Usp Units In Dextrose 5%
Oxytocin Acetate
Oxytocin injection
Oxytocine
Oxytocinum
Pitocin
Pitocin (TN)
Syntocinon
Syntocinon (TN)
TI-001
alpha-Hypophamine
nchembio.184-comp2
27
Dinoprostoneapproved88363-24-65280360
Synonyms:
(15S)-Prostaglandin E2
(15S)-Prostaglandin e2
(5Z,11-alpha,13E,15S)-11,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oic acid
(5Z,11.alpha.,13E,15S)-11,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oic acid
(5Z,11alpha,13E,15S)-11,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oic
(5Z,11alpha,13E,15S)-11,15-Dihydroxy-9-oxoprosta-5,13-dienoic acid
(5Z,11alpha,13E,15S)-11,15-dihydroxy-9-oxoprosta-5,13-dien-1-oic acid
(5Z,11alpha,13e,15S)-11,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oic acid
(5Z,13E)-(15S)-11alpha,15-Dihydroxy-9-oxoprost-13-enoate
(5Z,13E)-(15S)-11alpha,15-dihydroxy-9-oxoprosta-5,13-dienoate
(5Z,13E,15S)-11alpha,15-dihydroxy-9-oxoprosta-5,13-dien-1-oic acid
(5Z,13e)-(15S)-11alpha,15-Dihydroxy-9-oxoprost-13-enoate
(5Z,13e)-(15S)-11alpha,15-Dihydroxy-9-oxoprosta-5,13-dienoate
(E,Z)-(1R,2R,3R)-7-(3-Hydroxy-2-((3S)-(3-hydroxy-1-octenyl))-5-oxocyclopentyl)-5-heptenoic acid
(Z)-7-((1R,2R,3R)-3-Hydroxy-2-((S,e)-3-hydroxyoct-1-enyl)-5-oxocyclopentyl)hept-5-enoic acid
(Z)-7-[(1R,2R,3R)-3-Hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxocyclopentyl]hept-5-enoic acid
(e,Z)-(1R,2R,3R)-7-(3-Hydroxy-2-((3S)-(3-hydroxy-1-octenyl))-5-oxocyclopentyl)-5-heptenoic acid
05D31BD5-818B-4A92-8CFC-BEC19926A5B3
363-24-6
5-Heptenoic acid, 7-(3-hydroxy-2-(3-hydroxy-1-octenyl)-5-oxocyclopentyl)- (8CI)
7-(3-Hydroxy-2-(3-hydroxy-1-octenyl)-5-oxocyclopentyl)-5-heptenoic acid
AC-6098
AC1NQWXW
BML1-F07
BMS-279654 & PGE2
BRD-K26521938-001-04-9
BSPBio_001490
C00584
CHEBI:15551
CHEMBL548
CID5280360
Cervidil
Cervidil (TN)
D00079
D015232
DB00917
Dinoproston
Dinoprostona
Dinoprostona [INN-Spanish]
Dinoprostone
Dinoprostone (JAN/USP/INN)
Dinoprostone Prostaglandin E2
Dinoprostone [USAN:INN:BAN:JAN]
Dinoprostone beta-Cyclodextrin Clathrate
Dinoprostonum
Dinoprostonum [INN-Latin]
E2 alpha, Prostaglandin
E2, Prostaglandin
E2alpha, Prostaglandin
EINECS 206-656-6
Gel, Prepidil
 
HMS1361K12
HMS1791K12
HMS1989K12
HMS2089D17
IDI1_033960
LMFA03010003
LS-125823
Minprositin E2
Minprostin E2
MolPort-003-939-184
NCGC00092361-01
NCGC00092361-02
NCGC00092361-03
NCGC00092361-04
NCGC00092361-05
NSC 165560
NSC 196514
P0409_SIGMA
P5640_SIGMA
P6532_SIGMA
PGE2
PGE2 alpha
PGE2alpha
Prepidil
Prepidil (TN)
Prepidil Gel
Prestwick_793
Propess
Prostaglandin E2
Prostaglandin E2 alpha
Prostaglandin E2alpha
Prostarmon E
Prostarmon E2
Prostenon
Prostin
Prostin E
Prostin E2
Prostin E2 (TN)
Prostin e2
SMP2_000056
ST50826265
U 12062
U-12062
UNII-K7Q1JQR04M
[3H]PGE2
alpha, PGE2
alpha, Prostaglandin E2
l-7-(3-Hydroxy-2-(3-hydroxy-1-octenyl)-5-oxocyclopentyl)-5-heptenoic acid
l-PGE2
l-Prostaglandin E2
nchembio.106-comp6
nchembio.147-comp12
28Immunoglobulins6045
29Antibodies6045

Interventional clinical trials:

(show all 20)
idNameStatusNCT IDPhase
1Oral Sildenafil in Persistent Pulmonary Hypertension Secondary to Meconium Aspiration Syndrome in NewbornsCompletedNCT01757782Phase 4
2Lung Lavage With Dilute Poractant Alfa for Meconium Aspiration SyndromeCompletedNCT02041546Phase 4
3Cervical Ripening for Obese Women: A Randomized, Comparative Effectiveness TrialRecruitingNCT02639429Phase 4
4Surfactant Lavage vs. Bolus Surfactant in Neonates With Meconium AspirationUnknown statusNCT00312507Phase 3
5Phase III Randomized Study of Lucinactant in Full Term Newborn Infants With Meconium Aspiration SyndromeTerminatedNCT00004500Phase 3
6Inhaled Nitric Oxide Study for Respiratory Failure in NewbornsTerminatedNCT00005776Phase 3
7Early Inhaled Nitric Oxide for Respiratory Failure in NewbornsTerminatedNCT00005773Phase 3
8Inhaled PGE1 in Neonatal Hypoxemic Respiratory FailureWithdrawnNCT00598429Phase 2
9Efficacy and Safety of Gastric Suctioning During Neonatal ResuscitationUnknown statusNCT00729989
10Effect Of Intrapartum Oropharyngeal (IP-OP) Suction on Meconium Aspiration SyndromeCompletedNCT01328483
11Comparison Of Surfactant Lung Lavage With Standard Care In The Treatment Of Meconium Aspiration SyndromeCompletedNCT01310621
12Use of Heliox in the Management of Neonates With Meconium Aspiration SyndromeCompletedNCT01274845
13Role of Endotracheal Suction on the Occurrence of Meconium Aspiration Syndrome in Non-vigorous Meconium Stained BabiesCompletedNCT01758822
14Effect of Gastric Lavage in Preventing Feeding Problems in Babies Born With Meconium Stained Amniotic FluidCompletedNCT01306500
15Antibody Secreting Cell and Cyotokine Profiles in Neonates on ECMOCompletedNCT00371241
16Post Term Pregnancy - Induction of Labor or Monitoring of PregnancyCompletedNCT00385229
17Helium Oxygen Mixture in the Treatment of Meconium Aspiration SyndromeRecruitingNCT02620891
18Role and Molecular Mechanism of Farnesoid X Receptor(FXR) and RIPK3 in the Formation of Acute Respiratory Distress Syndrome in NeonatesRecruitingNCT02598648
19Meconium Aspiration and Tracheal Suctioning—Feasibility StudyNot yet recruitingNCT02708563
20High Flow Ventilation With Volume GuaranteeNot yet recruitingNCT02571231

Search NIH Clinical Center for Meconium Aspiration Syndrome


Cochrane evidence based reviews: meconium aspiration syndrome

Genetic Tests for Meconium Aspiration Syndrome

About this section

Anatomical Context for Meconium Aspiration Syndrome

About this section

MalaCards organs/tissues related to Meconium Aspiration Syndrome:

36
Lung, Uterus

Publications for Meconium Aspiration Syndrome

About this section

Articles related to Meconium Aspiration Syndrome:

(show top 50)    (show all 286)
idTitleAuthorsYear
1
Inflammation in meconium aspiration syndrome-One of many heads of the hydra. (26773259)
2016
2
Current Concepts in the Management of Meconium Aspiration Syndrome. (27206687)
2016
3
Lung inflammatory and oxidative alterations after exogenous surfactant therapy fortified with budesonide in rabbit model of meconium aspiration syndrome. (28006947)
2016
4
Hypothermia and Meconium Aspiration Syndrome: International Multicenter Retrospective Cohort Study. (27479063)
2016
5
Erythropoietin may attenuate lung inflammation in a rat model of meconium aspiration syndrome. (27266360)
2016
6
Surfactant therapy and antibiotics in neonates with meconium aspiration syndrome: a systematic review and meta-analysis. (27109092)
2016
7
Lung ultrasonography to diagnose meconium aspiration syndrome of the newborn. (27807253)
2016
8
Inflammatory indices in meconium aspiration syndrome. (26663621)
2016
9
Histologic Evidence of Intrapulmonary Bronchopulmonary Anastomotic Pathways in Neonates with Meconium Aspiration Syndrome. (26421487)
2015
10
Treatment of neonates with meconium aspiration syndrome by proportional assist ventilation and synchronized intermittent mandatory ventilation: a comparison study. (26633188)
2015
11
To study prevalence of persistent pulmonary hypertension in newborn with meconium aspiration syndrome in western Rajasthan, India: a prospective observational study. (25586320)
2015
12
Efficiency of high-frequency oscillatory ventilation combined with pulmonary surfactant in the treatment of neonatal meconium aspiration syndrome. (26550439)
2015
13
Meconium aspiration syndrome in infants of HIV-positive women: a case-control study. (25999326)
2015
14
Effect of intrapartum oropharyngeal (IP-OP) suction on meconium aspiration syndrome (MAS) in developing country: A RCT. (26449871)
2015
15
Meconium Aspiration Syndrome: A Role for Fetal Systemic Inflammation. (26484777)
2015
16
Surfactant with and without bronchoalveolar lavage in an experimental model of meconium aspiration syndrome. (25719289)
2015
17
Risk factors differentiating mild/moderate from severe meconium aspiration syndrome in meconium-stained neonates. (25629015)
2015
18
Tidal Volume Requirement in Mechanically Ventilated Infants with Meconium Aspiration Syndrome. (25738789)
2015
19
Effects on Lung Function of Small-Volume Conventional Ventilation and High-Frequency Oscillatory Ventilation in a Model of Meconium Aspiration Syndrome. (26017729)
2015
20
Meconium aspiration syndrome: possible pathophysiological mechanisms and future potential therapies. (25721501)
2015
21
N-acetylcysteine advancement of surfactant therapy in experimental meconium aspiration syndrome: possible mechanisms. (25669694)
2014
22
Secreted phospholipase A2 is increased in meconium-stained amniotic fluid of term gestations: potential implications for the genesis of meconium aspiration syndrome. (24063538)
2014
23
Predictors of mortality in neonates with meconium aspiration syndrome. (25128996)
2014
24
Surfactant for meconium aspiration syndrome in term and late preterm infants. (25504256)
2014
25
Predictors of mortality in neonates with meconium aspiration syndrome. (25128992)
2014
26
Blood lactate level and meconium aspiration syndrome. (25256123)
2014
27
Lung ultrasound findings in meconium aspiration syndrome. (25220126)
2014
28
Effects of Natural versus Synthetic Surfactant with SP-B and SP-C Analogs in a Porcine Model of Meconium Aspiration Syndrome. (24356240)
2013
29
Budesonide added to modified porcine surfactant Curosurf may additionally improve the lung functions in meconium aspiration syndrome. (24329699)
2013
30
Spectrophotometric analysis in umbilical cords of infants with meconium aspiration syndrome. (23743814)
2013
31
Fluid recovery during lung lavage in meconium aspiration syndrome. (23194445)
2013
32
High Asparatate Aminotransferase Level Predicts Poor Neurodevelopmental Outcome in Infants with Meconium Aspiration Syndrome. (24347255)
2013
33
Lung lavage for meconium aspiration syndrome in newborn infants. (23633311)
2013
34
Meconium Aspiration Syndrome - a 21-years' Experience from a Tertiary Care Center and Analysis of Risk Factors for Predicting Disease Severity. (24293080)
2013
35
A Case of Meconium Aspiration Syndrome in a Bottlenose Dolphin (Tursiops truncatus) Calf. (23966011)
2013
36
Lung lavage in meconium aspiration syndrome. (23662695)
2013
37
Anti-inflammatory treatment of meconium aspiration syndrome: benefits and risks. (23466955)
2013
38
Changes in Mean Arterial Blood Pressure During Sildenafil Use in Neonates With Meconium Aspiration Syndrome or Sepsis. (23344111)
2013
39
How to overcome surfactant dysfunction in meconium aspiration syndrome? (23473924)
2013
40
Respiratory distress including meconium aspiration syndrome in vigorous neonates born through meconium stained amniotic fluid: incidence, onset, severity and predictors at birth. (23188709)
2013
41
A Population-Based Study of Meconium Aspiration Syndrome in Neonates Born between 37 and 43 Weeks of Gestation. (22187569)
2012
42
Respiratory support in meconium aspiration syndrome: a practical guide. (22518190)
2012
43
Comparative effects of bronchoalveolar lavage with saline, surfactant, or perfluorocarbon in experimental meconium aspiration syndrome. (22079955)
2012
44
The effects of pentoxifylline on lung inflammation in a rat model of meconium aspiration syndrome. (22489651)
2012
45
Advances in the management of meconium aspiration syndrome. (22164183)
2012
46
Surfactant lavage therapy for meconium aspiration syndrome: a systematic review and meta-analysis. (22067375)
2012
47
Use of heliox in the management of neonates with meconium aspiration syndrome. (21701217)
2011
48
Trends in obstetric practices and meconium aspiration syndrome: a population-based study. (21895951)
2011
49
Glucocorticoids in the treatment of neonatal meconium aspiration syndrome. (21465122)
2011
50
Management of meconium aspiration syndrome with highfrequency oscillatory ventilation. (21780039)
2011

Variations for Meconium Aspiration Syndrome

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Expression for genes affiliated with Meconium Aspiration Syndrome

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Search GEO for disease gene expression data for Meconium Aspiration Syndrome.

Pathways for genes affiliated with Meconium Aspiration Syndrome

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Pathways related to Meconium Aspiration Syndrome according to GeneCards Suite gene sharing:

(show all 42)
idSuper pathwaysScoreTop Affiliating Genes
19.8EDN1, SCGB1A1
29.7CXCL8, TNF
39.7CXCL8, IL6
49.6IL6, TNF
59.6CSF2, CXCL8
69.3CXCL8, IL6, TNF
79.3CXCL8, IL6, TNF
89.3CXCL8, IL6, TNF
9
Show member pathways
9.3CXCL8, IL6, TNF
109.2CSF2, CXCL8, IL6
119.1CSF2, IL6, TNF
12
Show member pathways
8.9CXCL8, EDN1, IL6, TNF
138.9CXCL8, EDN1, IL6, TNF
148.9EDN1, IFNG, IL6
158.9CXCL8, IFNG, IL6
168.9CXCL8, IFNG, IL6
178.8IFNG, IL6, TNF
188.8IFNG, IL6, TNF
19
Show member pathways
8.8IFNG, IL6, TNF
208.8IFNG, IL6, TNF
218.8IFNG, IL6, TNF
228.8CSF2, EDN1, IL6, TNF
238.7CSF2, CXCL8, IL6, TNF
24
Show member pathways
8.7CSF2, IFNG, TNF
258.4CXCL8, IFNG, IL6, TNF
268.4CXCL8, IFNG, IL6, TNF
27
Show member pathways
8.4CXCL8, IFNG, IL6, TNF
28
Show member pathways
8.4CXCL8, IFNG, IL6, TNF
29
Show member pathways
8.4CXCL8, IFNG, IL6, TNF
308.4CXCL8, IFNG, IL6, TNF
31
Show member pathways
8.4CXCL8, IFNG, IL6, TNF
32
Show member pathways
8.4CXCL8, IFNG, IL6, TNF
33
Show member pathways
8.4CSF2, CXCL8, IFNG, TNF
348.3CSF2, CXCL8, IFNG, IL6
35
Show member pathways
8.3CSF2, CXCL8, IFNG, IL6
368.3CSF2, IFNG, IL6, TNF
378.3CSF2, IFNG, IL6, TNF
38
Show member pathways
8.3CSF2, IFNG, IL6, TNF
398.3CSF2, IFNG, IL6, TNF
407.9CSF2, CXCL8, IFNG, IL6, TNF
417.9CSF2, CXCL8, IFNG, IL6, TNF
42
Show member pathways
7.6CSF2, CXCL8, EDN1, IFNG, IL6, TNF

GO Terms for genes affiliated with Meconium Aspiration Syndrome

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Cellular components related to Meconium Aspiration Syndrome according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1external side of plasma membraneGO:00098979.6IFNG, IL6, TNF
2intracellularGO:00056228.0CSF2, CXCL8, IFNG, SCGB1A1, TNF
3extracellular regionGO:00055767.8CSF2, CXCL8, EDN1, IFNG, IL6, SFTPB
4extracellular spaceGO:00056157.4CSF2, CXCL8, EDN1, IFNG, IL6, SCGB1A1

Biological processes related to Meconium Aspiration Syndrome according to GeneCards Suite gene sharing:

(show all 38)
idNameGO IDScoreTop Affiliating Genes
1embryonic digestive tract developmentGO:004856610.5CXCL8, TNF
2negative regulation of hormone secretionGO:004688810.4EDN1, IL6
3epithelial fluid transportGO:004204510.4CSF2, EDN1
4histamine secretionGO:000182110.4CSF2, EDN1
5epithelial cell proliferation involved in salivary gland morphogenesisGO:006066410.4IL6, TNF
6negative regulation of lipid storageGO:001088810.4IL6, TNF
7positive regulation of chemokine productionGO:003272210.3IL6, TNF
8negative regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:200124010.3CSF2, TNF
9cellular response to fibroblast growth factor stimulusGO:004434410.3CPS1, CXCL8
10positive regulation of podosome assemblyGO:007180310.2CSF2, TNF
11response to dexamethasoneGO:007154810.2CPS1, EDN1
12cellular response to interleukin-1GO:007134710.1CXCL8, EDN1, IL6
13cellular response to tumor necrosis factorGO:007135610.1CXCL8, EDN1, IL6
14negative regulation of growth of symbiont in hostGO:004413010.0IFNG, TNF
15positive regulation of sequence-specific DNA binding transcription factor activityGO:005109110.0EDN1, IL6, TNF
16positive regulation of calcidiol 1-monooxygenase activityGO:006055910.0IFNG, TNF
17positive regulation of smooth muscle cell proliferationGO:004866110.0EDN1, IL6, TNF
18positive regulation of chemokine biosynthetic processGO:004508010.0IFNG, TNF
19positive regulation of membrane protein ectodomain proteolysisGO:005104410.0IFNG, TNF
20positive regulation of osteoclast differentiationGO:00456729.9IFNG, TNF
21defense response to protozoanGO:00428329.9IFNG, IL6
22neutrophil apoptotic processGO:00017819.9IFNG, IL6
23positive regulation of vitamin D biosynthetic processGO:00605579.9IFNG, TNF
24protein import into nucleus, translocationGO:00000609.9IFNG, TNF
25positive regulation of interleukin-23 productionGO:00327479.8CSF2, IFNG
26response to ozoneGO:00101939.8EDN1, SCGB1A1
27regulation of cell proliferationGO:00421279.8CSF2, IL6, TNF
28response to amino acidGO:00432009.7CPS1, EDN1, IL6
29neutrophil chemotaxisGO:00305939.7CXCL8, EDN1, IFNG
30response to silicon dioxideGO:00340219.6CSF2, SCGB1A1
31humoral immune responseGO:00069599.5IFNG, IL6, TNF
32response to glucocorticoidGO:00513849.2CPS1, IL6, SCGB1A1, TNF
33positive regulation of nitric oxide biosynthetic processGO:00454299.2EDN1, IFNG, IL6, TNF
34positive regulation of cell proliferationGO:00082849.1CSF2, EDN1, IFNG, IL6
35positive regulation of gene expressionGO:00106289.0CSF2, IFNG, IL6, TNF
36response to lipopolysaccharideGO:00324968.9CPS1, EDN1, IL6, SCGB1A1
37cellular response to lipopolysaccharideGO:00712228.7CSF2, CXCL8, IFNG, IL6, TNF
38response to drugGO:00424938.5CPS1, EDN1, IFNG, IL6, SCGB1A1

Molecular functions related to Meconium Aspiration Syndrome according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1cytokine activityGO:00051257.9CSF2, EDN1, IFNG, IL6, TNF

Sources for Meconium Aspiration Syndrome

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet