MCID: MCN007
MIFTS: 55

Meconium Aspiration Syndrome

Categories: Rare diseases, Fetal diseases, Respiratory diseases

Aliases & Classifications for Meconium Aspiration Syndrome

MalaCards integrated aliases for Meconium Aspiration Syndrome:

Name: Meconium Aspiration Syndrome 12 49 55 51 41 14 69
Neonatal Aspiration of Meconium 12
Meconium Aspiration 12
Mas 49

Characteristics:

Orphanet epidemiological data:

55
meconium aspiration syndrome
Inheritance: Not applicable; Prevalence: 1-9/100000 (Europe); Age of onset: Infancy,Neonatal;

Classifications:

Orphanet: 55  
Rare respiratory diseases


External Ids:

Disease Ontology 12 DOID:11049
MeSH 41 D008471
NCIt 46 C87093
Orphanet 55 ORPHA70588
MESH via Orphanet 42 D008471
UMLS via Orphanet 70 C0025048
ICD10 via Orphanet 33 P24.0
UMLS 69 C0025048

Summaries for Meconium Aspiration Syndrome

NIH Rare Diseases : 49 Meconium aspiration syndrome is a serious condition in which a newborn breathes a mixture of meconium and amniotic fluid into the lungs around the time of delivery. This can cause breathing difficulties due to swelling (inflammation) in the baby's lungs after birth. Treatment may include suctioning the newborn's mouth as soon as the head emerges during delivery, deep suctioning of the windpipe, antibiotics to treat infection, oxygen to keep blood levels normal, and radiant heat to maintain body temperature. In severe cases, the baby may need assistance breathing (ventilator). Last updated: 1/12/2012

MalaCards based summary : Meconium Aspiration Syndrome, also known as neonatal aspiration of meconium, is related to endocarditis and respiratory failure, and has symptoms including hoarseness, dyspnea and coughing. An important gene associated with Meconium Aspiration Syndrome is EDN1 (Endothelin 1), and among its related pathways/superpathways are PEDF Induced Signaling and Cytokine Signaling in Immune system. The drugs Misoprostol and Poractant alfa have been mentioned in the context of this disorder. Affiliated tissues include lung and uterus, and related phenotypes are Increased cell death in breast cancer cell lines (MCF10A, MDA-MB-435) and homeostasis/metabolism

Wikipedia : 72 Meconium aspiration syndrome (MAS) also known as neonatal aspiration of meconium is a medical condition... more...

Related Diseases for Meconium Aspiration Syndrome

Diseases related to Meconium Aspiration Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 249)
# Related Disease Score Top Affiliating Genes
1 endocarditis 29.8 CXCL8 IL6 TNF
2 respiratory failure 28.4 CXCL8 EDN1 SCGB1A1 SFTPB TNF
3 asthma 27.2 CSF2 CXCL8 EDN1 IFNG IL6 SCGB1A1
4 pulmonary hypertension, neonatal 11.2
5 recurrent corneal erosion 10.4 CXCL8 IL6
6 bagassosis 10.4 CXCL8 IL6
7 acute transverse myelitis 10.4 CXCL8 IL6
8 denture stomatitis 10.4 CXCL8 IL6
9 papillary conjunctivitis 10.4 CXCL8 IL6
10 funisitis 10.4 CXCL8 IL6
11 tungiasis 10.4 CXCL8 TNF
12 vaginal disease 10.4 CXCL8 IL6
13 vaginitis 10.4 CXCL8 IL6
14 preterm premature rupture of the membranes 10.4 CXCL8 IL6
15 trichuriasis 10.4 CXCL8 TNF
16 endometrial disease 10.4 CXCL8 IL6
17 haemophilus influenzae 10.4 CXCL8 TNF
18 scorpion envenomation 10.3 IL6 TNF
19 dental pulp disease 10.3 CXCL8 TNF
20 necrotizing fasciitis 10.3 CXCL8 IL6
21 mycobacterium abscessus 10.3 CXCL8 TNF
22 angioimmunoblastic lymphadenopathy with dysproteinemia 10.3 IL6 TNF
23 paraquat lung 10.3 SCGB1A1 SFTPB
24 critical limb ischemia 10.3 IL6 TNF
25 engraftment syndrome 10.3 CSF2 CXCL8
26 cowpox 10.3 CXCL8 IL6
27 null-cell leukemia 10.3 IL6 TNF
28 retinitis pigmentosa 55 10.3 IL6 TNF
29 toxic pneumonitis 10.3 SCGB1A1 SFTPB
30 felty syndrome 10.3 CSF2 CXCL8
31 bacteriuria 10.3 CXCL8 IL6
32 glossitis 10.3 IL6 TNF
33 laryngitis 10.3 IL6 TNF
34 anterior uveitis 10.3 IL6 TNF
35 acute vascular insufficiency of intestine 10.3 IL6 TNF
36 posterior urethral valves 10.3 IL6 TNF
37 poems syndrome 10.3 IL6 TNF
38 burning mouth syndrome 10.3 IL6 TNF
39 osteosclerotic myeloma 10.3 IL6 TNF
40 stachybotrys chartarum 10.3 IL6 TNF
41 neutrophilia, hereditary 10.3 CSF2 IL6
42 acute cystitis 10.3 CXCL8 IL6
43 listeriosis 10.3 IL6 TNF
44 crimean-congo hemorrhagic fever 10.3 IL6 TNF
45 tuberculous meningitis 10.3 CXCL8 TNF
46 ischemic heart disease 10.2 IL6 TNF
47 monoclonal gammopathy of uncertain significance 10.2 IL6 TNF
48 post-transplant lymphoproliferative disease 10.2 IL6 TNF
49 burns 10.2 CSF2 TNF
50 myelitis 10.2 IL6 TNF

Graphical network of the top 20 diseases related to Meconium Aspiration Syndrome:



Diseases related to Meconium Aspiration Syndrome

Symptoms & Phenotypes for Meconium Aspiration Syndrome

UMLS symptoms related to Meconium Aspiration Syndrome:


hoarseness, dyspnea, coughing, cheyne-stokes respiration, apnea

GenomeRNAi Phenotypes related to Meconium Aspiration Syndrome according to GeneCards Suite gene sharing:

25
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased cell death in breast cancer cell lines (MCF10A, MDA-MB-435) GR00104-A-0 8.8 CSF2 CXCL8 TNF

MGI Mouse Phenotypes related to Meconium Aspiration Syndrome:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.92 IL6 SCGB1A1 CPS1 SFTPB CSF2 TNF
2 mortality/aging MP:0010768 9.86 IFNG IL6 SCGB1A1 CPS1 SFTPB CSF2
3 endocrine/exocrine gland MP:0005379 9.85 IFNG IL6 SCGB1A1 CSF2 TNF EDN1
4 neoplasm MP:0002006 9.55 IL6 SCGB1A1 CSF2 TNF IFNG
5 renal/urinary system MP:0005367 9.35 IFNG IL6 SCGB1A1 CSF2 EDN1
6 respiratory system MP:0005388 9.1 IL6 SCGB1A1 SFTPB CSF2 TNF IFNG

Drugs & Therapeutics for Meconium Aspiration Syndrome

Drugs for Meconium Aspiration Syndrome (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 29)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Misoprostol Approved Phase 4 59122-46-2 5282381
2 Poractant alfa Approved Phase 4 129069-19-8
3
Citric Acid Approved, Nutraceutical, Vet_approved Phase 4 77-92-9 311
4 Respiratory System Agents Phase 4,Phase 3
5 Pulmonary Surfactants Phase 4,Phase 3
6 Sildenafil Citrate Phase 4 171599-83-0
7 Vasodilator Agents Phase 4,Phase 3
8 Pharmaceutical Solutions Phase 4
9 Phosphodiesterase 5 Inhibitors Phase 4
10 Phosphodiesterase Inhibitors Phase 4
11 Gastrointestinal Agents Phase 4
12 Oxytocics Phase 4
13 Antacids Phase 4
14 Anti-Ulcer Agents Phase 4
15 Citrate Nutraceutical Phase 4
16
Nitric Oxide Approved Phase 3 10102-43-9 145068
17 Neurotransmitter Agents Phase 3
18 Vasoconstrictor Agents Phase 3
19 Peripheral Nervous System Agents Phase 3
20 Anti-Asthmatic Agents Phase 3
21 Endothelium-Dependent Relaxing Factors Phase 3
22 Protective Agents Phase 3
23 Antioxidants Phase 3
24 Autonomic Agents Phase 3
25 Bronchodilator Agents Phase 3
26
Oxytocin Approved, Vet_approved 50-56-6 53477758 439302
27
Dinoprostone Approved 363-24-6 5280360
28 Immunoglobulins
29 Antibodies

Interventional clinical trials:

(show all 22)

# Name Status NCT ID Phase Drugs
1 Oral Sildenafil in Persistent Pulmonary Hypertension Secondary to Meconium Aspiration Syndrome in Newborns Completed NCT01757782 Phase 4 Oral Sildenafil;Placebo (distilled water)
2 Lung Lavage With Dilute Poractant Alfa for Meconium Aspiration Syndrome Completed NCT02041546 Phase 4 Lung lavage with surfactant;Bolus surfactant
3 Cervical Ripening for Obese Women: A Randomized, Comparative Effectiveness Trial Recruiting NCT02639429 Phase 4 Vaginal Misoprostol
4 Surfactant Lavage vs. Bolus Surfactant in Neonates With Meconium Aspiration Unknown status NCT00312507 Phase 3 Bovine Lipid Extract Surfactant (administered by lavage);Bovine Lipid Extract Surfactant (administered by bolus)
5 Phase III Randomized Study of Lucinactant in Full Term Newborn Infants With Meconium Aspiration Syndrome Terminated NCT00004500 Phase 3 Lucinactant
6 Inhaled Nitric Oxide Study for Respiratory Failure in Newborns Terminated NCT00005776 Phase 3 Inhaled nitric oxide;Placebo
7 Early Inhaled Nitric Oxide for Respiratory Failure in Newborns Terminated NCT00005773 Phase 3 Inhaled Nitric Oxide;Standard iNO therapy
8 Helium Oxygen Mixture in the Treatment of Meconium Aspiration Syndrome Unknown status NCT02620891
9 High Flow Ventilation With Volume Guarantee Unknown status NCT02571231
10 Role and Molecular Mechanism of Farnesoid X Receptor(FXR) and RIPK3 in the Formation of Acute Respiratory Distress Syndrome in Neonates Unknown status NCT02598648
11 Effect Of Intrapartum Oropharyngeal (IP-OP) Suction on Meconium Aspiration Syndrome Completed NCT01328483
12 Comparison Of Surfactant Lung Lavage With Standard Care In The Treatment Of Meconium Aspiration Syndrome Completed NCT01310621 Bovine surfactant
13 Use of Heliox in the Management of Neonates With Meconium Aspiration Syndrome Completed NCT01274845
14 Role of Endotracheal Suction on the Occurrence of Meconium Aspiration Syndrome in Non-vigorous Meconium Stained Babies Completed NCT01758822
15 Effect of Gastric Lavage in Preventing Feeding Problems in Babies Born With Meconium Stained Amniotic Fluid Completed NCT01306500
16 Antibody Secreting Cell and Cyotokine Profiles in Neonates on ECMO Completed NCT00371241
17 Post Term Pregnancy - Induction of Labor or Monitoring of Pregnancy Completed NCT00385229 induction of labor
18 Pulmonary Function Using Non-invasive Forced Oscillometry Recruiting NCT03346343
19 PREdelivery Placental Biomarkers- Pregnancy and Delivery Outcome Recruiting NCT03100084
20 Meconium Aspiration and Tracheal Suctioning—Feasibility Study Not yet recruiting NCT02708563
21 Prediction of Fetal Macrosomia by US Not yet recruiting NCT03451838
22 Efficacy and Safety of Gastric Suctioning During Neonatal Resuscitation Terminated NCT00729989

Search NIH Clinical Center for Meconium Aspiration Syndrome

Cochrane evidence based reviews: meconium aspiration syndrome

Genetic Tests for Meconium Aspiration Syndrome

Anatomical Context for Meconium Aspiration Syndrome

MalaCards organs/tissues related to Meconium Aspiration Syndrome:

38
Lung, Uterus

Publications for Meconium Aspiration Syndrome

Articles related to Meconium Aspiration Syndrome:

(show top 50) (show all 294)
# Title Authors Year
1
Controlled hypothermia may improve surfactant function in asphyxiated neonates with or without meconium aspiration syndrome. ( 29420583 )
2018
2
Effect of Nasal Continuous Positive Airway Pressure on Infants With Meconium Aspiration Syndrome: A Randomized Clinical Trial. ( 29204652 )
2018
3
Activation of Toll-like receptors in meconium aspiration syndrome. ( 29095429 )
2018
4
Meconium aspiration syndrome: risk factors and predictors of severity. ( 29219011 )
2017
5
Placental Lesions in Meconium Aspiration Syndrome. ( 28793392 )
2017
6
Outcome of Neonates with Meconium Aspiration Syndrome at the University Hospital of the West Indies, Jamaica: A Resource-Limited Setting. ( 28499308 )
2017
7
Procalcitonin as Predictor of Bacterial Infection in Meconium Aspiration Syndrome. ( 29287292 )
2017
8
Current Concepts in the Management of Meconium Aspiration Syndrome. ( 27206687 )
2016
9
Inflammatory indices in meconium aspiration syndrome. ( 26663621 )
2016
10
Erythropoietin may attenuate lung inflammation in a rat model of meconium aspiration syndrome. ( 27266360 )
2016
11
Lung ultrasonography to diagnose meconium aspiration syndrome of the newborn. ( 27807253 )
2016
12
Hypothermia and Meconium Aspiration Syndrome: International Multicenter Retrospective Cohort Study. ( 27479063 )
2016
13
Lung inflammatory and oxidative alterations after exogenous surfactant therapy fortified with budesonide in rabbit model of meconium aspiration syndrome. ( 28006947 )
2016
14
Surfactant therapy and antibiotics in neonates with meconium aspiration syndrome: a systematic review and meta-analysis. ( 27109092 )
2016
15
Inflammation in meconium aspiration syndrome-One of many heads of the hydra. ( 26773259 )
2016
16
Detrimental Complications Of Meconium Aspiration Syndrome And Their Impact On Outcome. ( 28712223 )
2016
17
Meconium aspiration syndrome in infants of HIV-positive women: a case-control study. ( 25999326 )
2015
18
Risk factors differentiating mild/moderate from severe meconium aspiration syndrome in meconium-stained neonates. ( 25629015 )
2015
19
Meconium Aspiration Syndrome: A Role for Fetal Systemic Inflammation. ( 26484777 )
2015
20
Treatment of neonates with meconium aspiration syndrome by proportional assist ventilation and synchronized intermittent mandatory ventilation: a comparison study. ( 26633188 )
2015
21
Effects on Lung Function of Small-Volume Conventional Ventilation and High-Frequency Oscillatory Ventilation in a Model of Meconium Aspiration Syndrome. ( 26017729 )
2015
22
Histologic Evidence of Intrapulmonary Bronchopulmonary Anastomotic Pathways in Neonates with Meconium Aspiration Syndrome. ( 26421487 )
2015
23
Tidal Volume Requirement in Mechanically Ventilated Infants with Meconium Aspiration Syndrome. ( 25738789 )
2015
24
Meconium aspiration syndrome: possible pathophysiological mechanisms and future potential therapies. ( 25721501 )
2015
25
Surfactant with and without bronchoalveolar lavage in an experimental model of meconium aspiration syndrome. ( 25719289 )
2015
26
Effect of intrapartum oropharyngeal (IP-OP) suction on meconium aspiration syndrome (MAS) in developing country: A RCT. ( 26449871 )
2015
27
Efficiency of high-frequency oscillatory ventilation combined with pulmonary surfactant in the treatment of neonatal meconium aspiration syndrome. ( 26550439 )
2015
28
To study prevalence of persistent pulmonary hypertension in newborn with meconium aspiration syndrome in western Rajasthan, India: a prospective observational study. ( 25586320 )
2015
29
Surfactant for meconium aspiration syndrome in term and late preterm infants. ( 25504256 )
2014
30
Blood lactate level and meconium aspiration syndrome. ( 25256123 )
2014
31
Secreted phospholipase A2 is increased in meconium-stained amniotic fluid of term gestations: potential implications for the genesis of meconium aspiration syndrome. ( 24063538 )
2014
32
Lung ultrasound findings in meconium aspiration syndrome. ( 25220126 )
2014
33
N-acetylcysteine advancement of surfactant therapy in experimental meconium aspiration syndrome: possible mechanisms. ( 25669694 )
2014
34
Predictors of mortality in neonates with meconium aspiration syndrome. ( 25128992 )
2014
35
Predictors of mortality in neonates with meconium aspiration syndrome. ( 25128996 )
2014
36
Effects of Natural versus Synthetic Surfactant with SP-B and SP-C Analogs in a Porcine Model of Meconium Aspiration Syndrome. ( 24356240 )
2013
37
Lung lavage in meconium aspiration syndrome. ( 23662695 )
2013
38
Fluid recovery during lung lavage in meconium aspiration syndrome. ( 23194445 )
2013
39
Lung lavage for meconium aspiration syndrome in newborn infants. ( 23633311 )
2013
40
How to overcome surfactant dysfunction in meconium aspiration syndrome? ( 23473924 )
2013
41
Meconium Aspiration Syndrome - a 21-years' Experience from a Tertiary Care Center and Analysis of Risk Factors for Predicting Disease Severity. ( 24293080 )
2013
42
A Case of Meconium Aspiration Syndrome in a Bottlenose Dolphin (Tursiops truncatus) Calf. ( 23966011 )
2013
43
Budesonide added to modified porcine surfactant Curosurf may additionally improve the lung functions in meconium aspiration syndrome. ( 24329699 )
2013
44
High Asparatate Aminotransferase Level Predicts Poor Neurodevelopmental Outcome in Infants with Meconium Aspiration Syndrome. ( 24347255 )
2013
45
Anti-inflammatory treatment of meconium aspiration syndrome: benefits and risks. ( 23466955 )
2013
46
Changes in Mean Arterial Blood Pressure During Sildenafil Use in Neonates With Meconium Aspiration Syndrome or Sepsis. ( 23344111 )
2013
47
Spectrophotometric analysis in umbilical cords of infants with meconium aspiration syndrome. ( 23743814 )
2013
48
Respiratory distress including meconium aspiration syndrome in vigorous neonates born through meconium stained amniotic fluid: incidence, onset, severity and predictors at birth. ( 23188709 )
2013
49
Respiratory support in meconium aspiration syndrome: a practical guide. ( 22518190 )
2012
50
A Population-Based Study of Meconium Aspiration Syndrome in Neonates Born between 37 and 43 Weeks of Gestation. ( 22187569 )
2012

Variations for Meconium Aspiration Syndrome

Expression for Meconium Aspiration Syndrome

Search GEO for disease gene expression data for Meconium Aspiration Syndrome.

Pathways for Meconium Aspiration Syndrome

Pathways related to Meconium Aspiration Syndrome according to GeneCards Suite gene sharing:

(show top 50) (show all 60)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.5 CSF2 CXCL8 EDN1 IFNG IL6 TNF
2
Show member pathways
13.22 CSF2 CXCL8 IFNG IL6 TNF
3
Show member pathways
12.85 CXCL8 EDN1 IL6 TNF
4
Show member pathways
12.73 CXCL8 IFNG IL6 TNF
5
Show member pathways
12.68 CXCL8 IFNG IL6 TNF
6
Show member pathways
12.62 CXCL8 IFNG IL6 TNF
7
Show member pathways
12.47 CSF2 CXCL8 IL6 TNF
8
Show member pathways
12.44 CXCL8 IFNG IL6 TNF
9
Show member pathways
12.35 CSF2 IFNG IL6 TNF
10
Show member pathways
12.26 CSF2 IFNG IL6
11
Show member pathways
12.23 IFNG IL6 TNF
12
Show member pathways
12.21 CXCL8 IFNG IL6 TNF
13
Show member pathways
12.17 CXCL8 IL6 TNF
14 12.16 CSF2 CXCL8 IL6
15
Show member pathways
12.16 CSF2 CXCL8 IFNG IL6 TNF
16 12.13 IFNG IL6 TNF
17
Show member pathways
12.12 CXCL8 IFNG IL6 TNF
18 12.09 IFNG IL6 TNF
19
Show member pathways
12.09 CXCL8 IFNG IL6 TNF
20 12.08 CXCL8 IL6 TNF
21 12 EDN1 IFNG TNF
22 11.95 CXCL8 IFNG IL6 TNF
23 11.92 CSF2 IFNG IL6 TNF
24 11.91 CXCL8 IL6 TNF
25 11.88 CSF2 EDN1 IL6 TNF
26 11.87 CXCL8 IFNG IL6
27
Show member pathways
11.86 IFNG IL6 TNF
28 11.84 EDN1 IFNG IL6
29 11.83 CSF2 IL6 TNF
30 11.82 CXCL8 EDN1 IL6 TNF
31
Show member pathways
11.8 CSF2 CXCL8 IL6
32 11.75 CSF2 CXCL8 IFNG IL6
33 11.71 CSF2 CXCL8 IFNG IL6
34 11.7 CXCL8 IL6 TNF
35
Show member pathways
11.66 CSF2 CXCL8 IFNG TNF
36 11.64 CSF2 CXCL8 IFNG IL6 TNF
37 11.63 CSF2 IFNG IL6 TNF
38 11.55 CXCL8 IFNG IL6
39 11.55 CXCL8 IL6 TNF
40 11.51 IFNG IL6 TNF
41 11.51 CSF2 CXCL8 IFNG IL6 TNF
42 11.45 IFNG IL6 TNF
43 11.4 CSF2 CXCL8 IL6 TNF
44 11.36 CXCL8 IFNG IL6 TNF
45
Show member pathways
11.34 CSF2 IFNG TNF
46 11.31 IFNG IL6 TNF
47 11.27 IL6 TNF
48 11.27 IFNG IL6 TNF
49 11.26 CXCL8 IL6
50 11.24 CSF2 CXCL8

GO Terms for Meconium Aspiration Syndrome

Cellular components related to Meconium Aspiration Syndrome according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.56 CSF2 CXCL8 EDN1 IFNG IL6 SCGB1A1
2 extracellular space GO:0005615 9.23 CSF2 CXCL8 EDN1 IFNG IL6 SCGB1A1

Biological processes related to Meconium Aspiration Syndrome according to GeneCards Suite gene sharing:

(show all 32)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of cell proliferation GO:0008284 9.92 CSF2 EDN1 IFNG IL6
2 positive regulation of gene expression GO:0010628 9.88 CSF2 IFNG IL6 TNF
3 response to lipopolysaccharide GO:0032496 9.81 CPS1 EDN1 SCGB1A1
4 positive regulation of DNA binding transcription factor activity GO:0051091 9.74 EDN1 IL6 TNF
5 immune response GO:0006955 9.72 CSF2 CXCL8 IFNG IL6 TNF
6 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.71 CSF2 IFNG IL6
7 positive regulation of smooth muscle cell proliferation GO:0048661 9.67 EDN1 IL6 TNF
8 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 9.65 CSF2 TNF
9 response to amino acid GO:0043200 9.65 CPS1 EDN1
10 cellular response to fibroblast growth factor stimulus GO:0044344 9.65 CPS1 CXCL8
11 humoral immune response GO:0006959 9.65 IFNG IL6 TNF
12 positive regulation of neutrophil chemotaxis GO:0090023 9.64 CXCL8 EDN1
13 protein import into nucleus, translocation GO:0000060 9.64 IFNG TNF
14 positive regulation of protein complex assembly GO:0031334 9.63 IFNG TNF
15 positive regulation of osteoclast differentiation GO:0045672 9.62 IFNG TNF
16 positive regulation of chemokine production GO:0032722 9.61 IL6 TNF
17 embryonic digestive tract development GO:0048566 9.61 CXCL8 TNF
18 positive regulation of membrane protein ectodomain proteolysis GO:0051044 9.6 IFNG TNF
19 response to dexamethasone GO:0071548 9.59 CPS1 EDN1
20 positive regulation of podosome assembly GO:0071803 9.58 CSF2 TNF
21 negative regulation of lipid storage GO:0010888 9.56 IL6 TNF
22 epithelial fluid transport GO:0042045 9.55 CSF2 EDN1
23 positive regulation of nitric oxide biosynthetic process GO:0045429 9.54 EDN1 IFNG TNF
24 response to ozone GO:0010193 9.52 EDN1 SCGB1A1
25 positive regulation of interleukin-23 production GO:0032747 9.51 CSF2 IFNG
26 histamine secretion GO:0001821 9.46 CSF2 EDN1
27 cellular response to lipopolysaccharide GO:0071222 9.46 CSF2 CXCL8 IL6 TNF
28 response to silicon dioxide GO:0034021 9.43 CSF2 SCGB1A1
29 positive regulation of calcidiol 1-monooxygenase activity GO:0060559 9.4 IFNG TNF
30 positive regulation of vitamin D biosynthetic process GO:0060557 9.26 IFNG TNF
31 response to glucocorticoid GO:0051384 9.26 CPS1 IL6 SCGB1A1 TNF
32 regulation of receptor activity GO:0010469 9.1 CSF2 CXCL8 EDN1 IFNG IL6 TNF

Molecular functions related to Meconium Aspiration Syndrome according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.1 CSF2 CXCL8 EDN1 IFNG IL6 TNF

Sources for Meconium Aspiration Syndrome

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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