MCID: MCN007
MIFTS: 51

Meconium Aspiration Syndrome

Categories: Rare diseases, Fetal diseases, Respiratory diseases

Aliases & Classifications for Meconium Aspiration Syndrome

MalaCards integrated aliases for Meconium Aspiration Syndrome:

Name: Meconium Aspiration Syndrome 12 50 56 52 42 14 69
Neonatal Aspiration of Meconium 12
Meconium Aspiration 12
Mas 50

Characteristics:

Orphanet epidemiological data:

56
meconium aspiration syndrome
Inheritance: Not applicable; Prevalence: 1-9/100000 (Europe); Age of onset: Infancy,Neonatal;

Classifications:

Orphanet: 56  
Rare respiratory diseases


External Ids:

Disease Ontology 12 DOID:11049
MeSH 42 D008471
NCIt 47 C87093
Orphanet 56 ORPHA70588
MESH via Orphanet 43 D008471
UMLS via Orphanet 70 C0025048
ICD10 via Orphanet 34 P24.0
UMLS 69 C0025048

Summaries for Meconium Aspiration Syndrome

NIH Rare Diseases : 50 meconium aspiration syndrome is a serious condition in which a newborn breathes a mixture of meconium and amniotic fluid into the lungs around the time of delivery. this can cause breathing difficulties due to swelling (inflammation) in the baby's lungs after birth. treatment may include suctioning the newborn's mouth as soon as the head emerges during delivery, deep suctioning of the windpipe, antibiotics to treat infection, oxygen to keep blood levels normal, and radiant heat to maintain body temperature. in severe cases, the baby may need assistance breathing (ventilator). last updated: 1/12/2012

MalaCards based summary : Meconium Aspiration Syndrome, also known as neonatal aspiration of meconium, is related to asthma and pulmonary hypertension, neonatal, and has symptoms including cheyne-stokes respiration, coughing and dyspnea. An important gene associated with Meconium Aspiration Syndrome is EDN1 (Endothelin 1), and among its related pathways/superpathways are PEDF Induced Signaling and Cytokine Signaling in Immune system. The drugs Poractant alfa and Misoprostol have been mentioned in the context of this disorder. Affiliated tissues include lung and uterus, and related phenotypes are Increased cell death in breast cancer cell lines (MCF10A, MDA-MB-435) and homeostasis/metabolism

Wikipedia : 72 Meconium aspiration syndrome (MAS) also known as neonatal aspiration of meconium is a medical condition... more...

Related Diseases for Meconium Aspiration Syndrome

Diseases related to Meconium Aspiration Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 250)
id Related Disease Score Top Affiliating Genes
1 asthma 26.4 CSF2 CXCL8 EDN1 IFNG IL6 SCGB1A1
2 pulmonary hypertension, neonatal 11.0
3 oculomotor nerve paralysis 10.6 CXCL8 IL6
4 common peroneal nerve lesion 10.6 CXCL8 IL6
5 drug rash with eosinophilia and systemic symptoms 10.6 CXCL8 IL6
6 schwannoma of ureter 10.6 CXCL8 IL6
7 psychotic disorder 10.6 CXCL8 IL6
8 infancy electroclinical syndrome 10.6 CXCL8 IL6
9 basidiobolomycosis 10.6 CXCL8 TNF
10 osteogenesis imperfecta, type x 10.6 CXCL8 IL6
11 subglottis neoplasm 10.6 CXCL8 IL6
12 tarsal tunnel syndrome 10.6 CXCL8 TNF
13 bullous retinoschisis 10.6 CXCL8 IL6
14 halal setton wang syndrome 10.5 CXCL8 TNF
15 carbuncle 10.5 CXCL8 IL6
16 smarca4-deficient sarcoma of thorax 10.5 IL6 TNF
17 autosomal dominant polycystic kidney disease 10.5 CXCL8 IL6
18 orthostatic proteinuria 10.5 CXCL8 IL6
19 epulis 10.5 CXCL8 TNF
20 mycobacterium kansasii 10.5 CXCL8 TNF
21 aortic arch interruption 10.5 IL6 TNF
22 paroxysmal cold hemoglobinuria 10.5 SCGB1A1 SFTPB
23 cutaneous leishmaniasis 10.5 IL6 TNF
24 enterovesical fistula 10.5 CSF2 CXCL8
25 toxoplasmosis 10.5 IL6 TNF
26 trachea sarcoma 10.5 CXCL8 TNF
27 dyslexia 5 10.5 IL6 TNF
28 epstein-barr virus hepatitis 10.5 IL6 TNF
29 scrotal carcinoma 10.5 IL6 TNF
30 anencephaly and spina bifida x-linked 10.5 IL6 TNF
31 antigen-peptide-transporter 2 deficiency 10.5 IL6 TNF
32 pediculus humanus corporis infestation 10.5 SCGB1A1 SFTPB
33 lymphangiectasia, intestinal 10.5 CSF2 CXCL8
34 papilledema 10.5 IL6 TNF
35 ethmoid sinus adenocarcinoma 10.5 IL6 TNF
36 myofascial pain syndrome 10.5 CXCL8 IL6
37 upper gum cancer 10.5 IL6 TNF
38 potato nose 10.5 IL6 TNF
39 bipolar i disorder 10.5 IL6 TNF
40 lateral cystocele 10.5 CXCL8 IL6
41 tinea favosa 10.5 IL6 TNF
42 central nervous system leiomyosarcoma 10.5 IL6 TNF
43 indolent myeloma 10.5 IL6 TNF
44 stargardt macular degeneration absent or hypoplastic corpus callosum mental retardation and dysmorphic features 10.5 IL6 TNF
45 brachydactyly-distal symphalangism syndrome 10.4 CSF2 IL6
46 tumefactive multiple sclerosis 10.4 CXCL8 TNF
47 vogt-koyanagi-harada disease 10.4 IL6 TNF
48 phlyctenulosis 10.4 IL6 TNF
49 allergic bronchopulmonary aspergillosis 10.4 CXCL8 IL6
50 islet cell tumor 10.4 IL6 TNF

Graphical network of the top 20 diseases related to Meconium Aspiration Syndrome:



Diseases related to Meconium Aspiration Syndrome

Symptoms & Phenotypes for Meconium Aspiration Syndrome

UMLS symptoms related to Meconium Aspiration Syndrome:


cheyne-stokes respiration, coughing, dyspnea, hoarseness

GenomeRNAi Phenotypes related to Meconium Aspiration Syndrome according to GeneCards Suite gene sharing:

26
id Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased cell death in breast cancer cell lines (MCF10A, MDA-MB-435) GR00104-A-0 8.8 TNF CSF2 CXCL8

MGI Mouse Phenotypes related to Meconium Aspiration Syndrome:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.92 CPS1 CSF2 EDN1 IFNG IL6 SCGB1A1
2 mortality/aging MP:0010768 9.86 CPS1 CSF2 EDN1 IFNG IL6 SCGB1A1
3 endocrine/exocrine gland MP:0005379 9.85 SCGB1A1 TNF CSF2 EDN1 IFNG IL6
4 neoplasm MP:0002006 9.55 CSF2 IFNG IL6 SCGB1A1 TNF
5 renal/urinary system MP:0005367 9.35 CSF2 EDN1 IFNG IL6 SCGB1A1
6 respiratory system MP:0005388 9.1 IL6 SCGB1A1 SFTPB TNF CSF2 IFNG

Drugs & Therapeutics for Meconium Aspiration Syndrome

Drugs for Meconium Aspiration Syndrome (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 29)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1 Poractant alfa Approved Phase 4 129069-19-8
2
Misoprostol Approved Phase 4 59122-46-2 5282381
3 Pulmonary Surfactants Phase 4,Phase 3
4 Respiratory System Agents Phase 4,Phase 3
5 Pharmaceutical Solutions Phase 4
6 Phosphodiesterase 5 Inhibitors Phase 4
7 Phosphodiesterase Inhibitors Phase 4
8 Sildenafil Citrate Phase 4 171599-83-0
9 Vasodilator Agents Phase 4,Phase 3
10 Antacids Phase 4
11 Anti-Ulcer Agents Phase 4
12 Gastrointestinal Agents Phase 4
13 Oxytocics Phase 4
14 Citrate Nutraceutical Phase 4
15
Citric Acid Nutraceutical, Vet_approved Phase 4 77-92-9 311
16
Nitric Oxide Approved Phase 3 10102-43-9 145068
17 Vasoconstrictor Agents Phase 3
18 Anti-Asthmatic Agents Phase 3
19 Antioxidants Phase 3
20 Autonomic Agents Phase 3
21 Bronchodilator Agents Phase 3
22 Endothelium-Dependent Relaxing Factors Phase 3
23 Neurotransmitter Agents Phase 3
24 Peripheral Nervous System Agents Phase 3
25 Protective Agents Phase 3
26
Dinoprostone Approved 363-24-6 5280360
27
Oxytocin Approved, Vet_approved 50-56-6 439302 53477758
28 Antibodies
29 Immunoglobulins

Interventional clinical trials:

(show all 20)

id Name Status NCT ID Phase Drugs
1 Oral Sildenafil in Persistent Pulmonary Hypertension Secondary to Meconium Aspiration Syndrome in Newborns Completed NCT01757782 Phase 4 Oral Sildenafil;Placebo (distilled water)
2 Lung Lavage With Dilute Poractant Alfa for Meconium Aspiration Syndrome Completed NCT02041546 Phase 4 Lung lavage with surfactant;Bolus surfactant
3 Cervical Ripening for Obese Women: A Randomized, Comparative Effectiveness Trial Recruiting NCT02639429 Phase 4 Vaginal Misoprostol
4 Surfactant Lavage vs. Bolus Surfactant in Neonates With Meconium Aspiration Unknown status NCT00312507 Phase 3 Bovine Lipid Extract Surfactant (administered by lavage);Bovine Lipid Extract Surfactant (administered by bolus)
5 Phase III Randomized Study of Lucinactant in Full Term Newborn Infants With Meconium Aspiration Syndrome Terminated NCT00004500 Phase 3 Lucinactant
6 Inhaled Nitric Oxide Study for Respiratory Failure in Newborns Terminated NCT00005776 Phase 3 Inhaled nitric oxide;Placebo
7 Early Inhaled Nitric Oxide for Respiratory Failure in Newborns Terminated NCT00005773 Phase 3 Inhaled Nitric Oxide;Standard iNO therapy
8 High Flow Ventilation With Volume Guarantee Unknown status NCT02571231
9 Effect Of Intrapartum Oropharyngeal (IP-OP) Suction on Meconium Aspiration Syndrome Completed NCT01328483
10 Comparison Of Surfactant Lung Lavage With Standard Care In The Treatment Of Meconium Aspiration Syndrome Completed NCT01310621 Bovine surfactant
11 Use of Heliox in the Management of Neonates With Meconium Aspiration Syndrome Completed NCT01274845
12 Role of Endotracheal Suction on the Occurrence of Meconium Aspiration Syndrome in Non-vigorous Meconium Stained Babies Completed NCT01758822
13 Effect of Gastric Lavage in Preventing Feeding Problems in Babies Born With Meconium Stained Amniotic Fluid Completed NCT01306500
14 Antibody Secreting Cell and Cyotokine Profiles in Neonates on ECMO Completed NCT00371241
15 Post Term Pregnancy - Induction of Labor or Monitoring of Pregnancy Completed NCT00385229 induction of labor
16 Helium Oxygen Mixture in the Treatment of Meconium Aspiration Syndrome Recruiting NCT02620891
17 Role and Molecular Mechanism of Farnesoid X Receptor(FXR) and RIPK3 in the Formation of Acute Respiratory Distress Syndrome in Neonates Recruiting NCT02598648
18 PREdelivery Placental Biomarkers- Pregnancy and Delivery Outcome Recruiting NCT03100084
19 Meconium Aspiration and Tracheal Suctioning—Feasibility Study Not yet recruiting NCT02708563
20 Efficacy and Safety of Gastric Suctioning During Neonatal Resuscitation Terminated NCT00729989

Search NIH Clinical Center for Meconium Aspiration Syndrome

Cochrane evidence based reviews: meconium aspiration syndrome

Genetic Tests for Meconium Aspiration Syndrome

Anatomical Context for Meconium Aspiration Syndrome

MalaCards organs/tissues related to Meconium Aspiration Syndrome:

39
Lung, Uterus

Publications for Meconium Aspiration Syndrome

Articles related to Meconium Aspiration Syndrome:

(show top 50) (show all 289)
id Title Authors Year
1
Placental Lesions in Meconium Aspiration Syndrome. ( 28793392 )
2017
2
Outcome of Neonates with Meconium Aspiration Syndrome at the University Hospital of the West Indies, Jamaica: A Resource-Limited Setting. ( 28499308 )
2017
3
Detrimental Complications Of Meconium Aspiration Syndrome And Their Impact On Outcome. ( 28712223 )
2016
4
Surfactant therapy and antibiotics in neonates with meconium aspiration syndrome: a systematic review and meta-analysis. ( 27109092 )
2016
5
Current Concepts in the Management of Meconium Aspiration Syndrome. ( 27206687 )
2016
6
Hypothermia and Meconium Aspiration Syndrome: International Multicenter Retrospective Cohort Study. ( 27479063 )
2016
7
Inflammatory indices in meconium aspiration syndrome. ( 26663621 )
2016
8
Lung ultrasonography to diagnose meconium aspiration syndrome of the newborn. ( 27807253 )
2016
9
Erythropoietin may attenuate lung inflammation in a rat model of meconium aspiration syndrome. ( 27266360 )
2016
10
Lung inflammatory and oxidative alterations after exogenous surfactant therapy fortified with budesonide in rabbit model of meconium aspiration syndrome. ( 28006947 )
2016
11
Inflammation in meconium aspiration syndrome-One of many heads of the hydra. ( 26773259 )
2016
12
Meconium aspiration syndrome: possible pathophysiological mechanisms and future potential therapies. ( 25721501 )
2015
13
Meconium aspiration syndrome in infants of HIV-positive women: a case-control study. ( 25999326 )
2015
14
To study prevalence of persistent pulmonary hypertension in newborn with meconium aspiration syndrome in western Rajasthan, India: a prospective observational study. ( 25586320 )
2015
15
Meconium Aspiration Syndrome: A Role for Fetal Systemic Inflammation. ( 26484777 )
2015
16
Efficiency of high-frequency oscillatory ventilation combined with pulmonary surfactant in the treatment of neonatal meconium aspiration syndrome. ( 26550439 )
2015
17
Histologic Evidence of Intrapulmonary Bronchopulmonary Anastomotic Pathways in Neonates with Meconium Aspiration Syndrome. ( 26421487 )
2015
18
Risk factors differentiating mild/moderate from severe meconium aspiration syndrome in meconium-stained neonates. ( 25629015 )
2015
19
Effect of intrapartum oropharyngeal (IP-OP) suction on meconium aspiration syndrome (MAS) in developing country: A RCT. ( 26449871 )
2015
20
Tidal Volume Requirement in Mechanically Ventilated Infants with Meconium Aspiration Syndrome. ( 25738789 )
2015
21
Effects on Lung Function of Small-Volume Conventional Ventilation and High-Frequency Oscillatory Ventilation in a Model of Meconium Aspiration Syndrome. ( 26017729 )
2015
22
Treatment of neonates with meconium aspiration syndrome by proportional assist ventilation and synchronized intermittent mandatory ventilation: a comparison study. ( 26633188 )
2015
23
Surfactant with and without bronchoalveolar lavage in an experimental model of meconium aspiration syndrome. ( 25719289 )
2015
24
Predictors of mortality in neonates with meconium aspiration syndrome. ( 25128996 )
2014
25
Surfactant for meconium aspiration syndrome in term and late preterm infants. ( 25504256 )
2014
26
Predictors of mortality in neonates with meconium aspiration syndrome. ( 25128992 )
2014
27
Secreted phospholipase A2 is increased in meconium-stained amniotic fluid of term gestations: potential implications for the genesis of meconium aspiration syndrome. ( 24063538 )
2014
28
Lung ultrasound findings in meconium aspiration syndrome. ( 25220126 )
2014
29
Blood lactate level and meconium aspiration syndrome. ( 25256123 )
2014
30
N-acetylcysteine advancement of surfactant therapy in experimental meconium aspiration syndrome: possible mechanisms. ( 25669694 )
2014
31
Anti-inflammatory treatment of meconium aspiration syndrome: benefits and risks. ( 23466955 )
2013
32
Lung lavage in meconium aspiration syndrome. ( 23662695 )
2013
33
Spectrophotometric analysis in umbilical cords of infants with meconium aspiration syndrome. ( 23743814 )
2013
34
High Asparatate Aminotransferase Level Predicts Poor Neurodevelopmental Outcome in Infants with Meconium Aspiration Syndrome. ( 24347255 )
2013
35
Changes in Mean Arterial Blood Pressure During Sildenafil Use in Neonates With Meconium Aspiration Syndrome or Sepsis. ( 23344111 )
2013
36
Lung lavage for meconium aspiration syndrome in newborn infants. ( 23633311 )
2013
37
Respiratory distress including meconium aspiration syndrome in vigorous neonates born through meconium stained amniotic fluid: incidence, onset, severity and predictors at birth. ( 23188709 )
2013
38
Budesonide added to modified porcine surfactant Curosurf may additionally improve the lung functions in meconium aspiration syndrome. ( 24329699 )
2013
39
Meconium Aspiration Syndrome - a 21-years' Experience from a Tertiary Care Center and Analysis of Risk Factors for Predicting Disease Severity. ( 24293080 )
2013
40
A Case of Meconium Aspiration Syndrome in a Bottlenose Dolphin (Tursiops truncatus) Calf. ( 23966011 )
2013
41
How to overcome surfactant dysfunction in meconium aspiration syndrome? ( 23473924 )
2013
42
Effects of Natural versus Synthetic Surfactant with SP-B and SP-C Analogs in a Porcine Model of Meconium Aspiration Syndrome. ( 24356240 )
2013
43
Fluid recovery during lung lavage in meconium aspiration syndrome. ( 23194445 )
2013
44
Advances in the management of meconium aspiration syndrome. ( 22164183 )
2012
45
Comparative effects of bronchoalveolar lavage with saline, surfactant, or perfluorocarbon in experimental meconium aspiration syndrome. ( 22079955 )
2012
46
A Population-Based Study of Meconium Aspiration Syndrome in Neonates Born between 37 and 43 Weeks of Gestation. ( 22187569 )
2012
47
Surfactant lavage therapy for meconium aspiration syndrome: a systematic review and meta-analysis. ( 22067375 )
2012
48
Respiratory support in meconium aspiration syndrome: a practical guide. ( 22518190 )
2012
49
The effects of pentoxifylline on lung inflammation in a rat model of meconium aspiration syndrome. ( 22489651 )
2012
50
Use of heliox in the management of neonates with meconium aspiration syndrome. ( 21701217 )
2011

Variations for Meconium Aspiration Syndrome

Expression for Meconium Aspiration Syndrome

Search GEO for disease gene expression data for Meconium Aspiration Syndrome.

Pathways for Meconium Aspiration Syndrome

Pathways related to Meconium Aspiration Syndrome according to GeneCards Suite gene sharing:

(show top 50) (show all 56)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
13.5 CSF2 CXCL8 EDN1 IFNG IL6 TNF
2
Show member pathways
13.22 CSF2 CXCL8 IFNG IL6 TNF
3
Show member pathways
12.85 CXCL8 EDN1 IL6 TNF
4
Show member pathways
12.75 CXCL8 IFNG IL6 TNF
5
Show member pathways
12.73 CXCL8 IFNG IL6 TNF
6
Show member pathways
12.67 CXCL8 IFNG IL6 TNF
7
Show member pathways
12.62 CXCL8 IFNG IL6 TNF
8
Show member pathways
12.35 CSF2 IFNG IL6 TNF
9
Show member pathways
12.21 CXCL8 IFNG IL6 TNF
10
Show member pathways
12.16 CSF2 CXCL8 IFNG IL6 TNF
11 12.14 CSF2 CXCL8 IL6
12 12.13 IFNG IL6 TNF
13
Show member pathways
12.12 CXCL8 IFNG IL6 TNF
14
Show member pathways
12.11 CSF2 IFNG IL6
15 12.09 IFNG IL6 TNF
16
Show member pathways
12.09 CXCL8 IFNG IL6 TNF
17 12.08 CXCL8 IL6 TNF
18 12 EDN1 IFNG TNF
19 11.95 CXCL8 IFNG IL6 TNF
20 11.93 CSF2 IFNG IL6 TNF
21 11.9 CXCL8 IL6 TNF
22 11.88 CSF2 EDN1 IL6 TNF
23 11.87 CXCL8 IFNG IL6
24
Show member pathways
11.87 IFNG IL6 TNF
25 11.83 EDN1 IFNG IL6
26 11.82 CSF2 IL6 TNF
27 11.82 CXCL8 EDN1 IL6 TNF
28
Show member pathways
11.8 CSF2 CXCL8 IL6
29 11.75 CSF2 CXCL8 IFNG IL6
30 11.71 CSF2 CXCL8 IFNG IL6
31 11.7 CXCL8 IL6 TNF
32
Show member pathways
11.66 CSF2 CXCL8 IFNG TNF
33 11.64 CSF2 IFNG IL6 TNF
34 11.64 CSF2 CXCL8 IFNG IL6 TNF
35 11.55 CXCL8 IFNG IL6
36 11.55 CXCL8 IL6 TNF
37 11.51 IFNG IL6 TNF
38 11.51 CSF2 CXCL8 IFNG IL6 TNF
39 11.45 IFNG IL6 TNF
40 11.4 CSF2 CXCL8 IL6 TNF
41
Show member pathways
11.38 CSF2 IFNG TNF
42 11.36 CXCL8 IFNG IL6 TNF
43 11.31 IFNG IL6 TNF
44 11.27 IFNG IL6 TNF
45 11.26 IL6 TNF
46 11.25 CXCL8 IL6
47 11.23 CSF2 CXCL8
48 11.2 IL6 TNF
49 11.19 EDN1 SCGB1A1
50 11.15 CSF2 CXCL8 IL6 TNF

GO Terms for Meconium Aspiration Syndrome

Cellular components related to Meconium Aspiration Syndrome according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.56 CSF2 CXCL8 EDN1 IFNG IL6 SCGB1A1
2 extracellular space GO:0005615 9.23 CSF2 CXCL8 EDN1 IFNG IL6 SCGB1A1

Biological processes related to Meconium Aspiration Syndrome according to GeneCards Suite gene sharing:

(show all 42)
id Name GO ID Score Top Affiliating Genes
1 positive regulation of cell proliferation GO:0008284 9.97 CSF2 EDN1 IFNG IL6
2 positive regulation of gene expression GO:0010628 9.92 CSF2 IFNG IL6 TNF
3 regulation of cell proliferation GO:0042127 9.86 CSF2 IL6 TNF
4 cellular response to tumor necrosis factor GO:0071356 9.82 CXCL8 EDN1 IL6
5 positive regulation of sequence-specific DNA binding transcription factor activity GO:0051091 9.81 EDN1 IL6 TNF
6 immune response GO:0006955 9.8 CSF2 CXCL8 IFNG IL6 TNF
7 cellular response to interleukin-1 GO:0071347 9.77 CXCL8 EDN1 IL6
8 neutrophil chemotaxis GO:0030593 9.75 CXCL8 EDN1 IFNG
9 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.74 CSF2 IFNG IL6
10 response to lipopolysaccharide GO:0032496 9.73 CPS1 EDN1 IL6 SCGB1A1
11 positive regulation of smooth muscle cell proliferation GO:0048661 9.71 EDN1 IL6 TNF
12 humoral immune response GO:0006959 9.7 IFNG IL6 TNF
13 cellular response to fibroblast growth factor stimulus GO:0044344 9.68 CPS1 CXCL8
14 positive regulation of neutrophil chemotaxis GO:0090023 9.68 CXCL8 EDN1
15 protein import into nucleus, translocation GO:0000060 9.68 IFNG TNF
16 positive regulation of protein complex assembly GO:0031334 9.68 IFNG TNF
17 defense response to protozoan GO:0042832 9.67 IFNG IL6
18 positive regulation of osteoclast differentiation GO:0045672 9.67 IFNG TNF
19 embryonic digestive tract development GO:0048566 9.66 CXCL8 TNF
20 positive regulation of chemokine production GO:0032722 9.66 IL6 TNF
21 positive regulation of membrane protein ectodomain proteolysis GO:0051044 9.65 IFNG TNF
22 negative regulation of growth of symbiont in host GO:0044130 9.65 IFNG TNF
23 response to drug GO:0042493 9.65 CPS1 EDN1 IFNG IL6 SCGB1A1
24 response to dexamethasone GO:0071548 9.64 CPS1 EDN1
25 positive regulation of protein import into nucleus, translocation GO:0033160 9.64 IFNG IL6
26 positive regulation of podosome assembly GO:0071803 9.63 CSF2 TNF
27 negative regulation of hormone secretion GO:0046888 9.62 EDN1 IL6
28 positive regulation of chemokine biosynthetic process GO:0045080 9.61 IFNG TNF
29 negative regulation of lipid storage GO:0010888 9.61 IL6 TNF
30 epithelial fluid transport GO:0042045 9.59 CSF2 EDN1
31 epithelial cell proliferation involved in salivary gland morphogenesis GO:0060664 9.58 IL6 TNF
32 response to ozone GO:0010193 9.56 EDN1 SCGB1A1
33 positive regulation of interleukin-23 production GO:0032747 9.55 CSF2 IFNG
34 histamine secretion GO:0001821 9.51 CSF2 EDN1
35 response to amino acid GO:0043200 9.5 CPS1 EDN1 IL6
36 response to silicon dioxide GO:0034021 9.49 CSF2 SCGB1A1
37 neutrophil apoptotic process GO:0001781 9.48 IFNG IL6
38 positive regulation of calcidiol 1-monooxygenase activity GO:0060559 9.46 IFNG TNF
39 response to glucocorticoid GO:0051384 9.46 CPS1 IL6 SCGB1A1 TNF
40 positive regulation of vitamin D biosynthetic process GO:0060557 9.37 IFNG TNF
41 positive regulation of nitric oxide biosynthetic process GO:0045429 9.26 EDN1 IFNG IL6 TNF
42 cellular response to lipopolysaccharide GO:0071222 9.02 CSF2 CXCL8 IFNG IL6 TNF

Molecular functions related to Meconium Aspiration Syndrome according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.1 CSF2 CXCL8 EDN1 IFNG IL6 TNF

Sources for Meconium Aspiration Syndrome

3 CDC
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10 dbSNP
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