MCID: MDN001
MIFTS: 29

Median Rhomboid Glossitis malady

Gastrointestinal diseases, Oral diseases categories

Aliases & Classifications for Median Rhomboid Glossitis

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Aliases & Descriptions for Median Rhomboid Glossitis:

Name: Median Rhomboid Glossitis 10 12
 
Persistent Tuberculum Impar 10


Classifications:



External Ids:

Disease Ontology10 DOID:14111
ICD9CM29 529.2
SNOMED-CT59 7522008
ICD1027 K14.2

Summaries for Median Rhomboid Glossitis

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Wikipedia:68 Median rhomboid glossitis (MRG, also known as central papillary atrophy, or glossal central papillary... more...

MalaCards based summary: Median Rhomboid Glossitis, also known as persistent tuberculum impar, is related to glossitis and geographic tongue. An important gene associated with Median Rhomboid Glossitis is KRT6B (Keratin 6B, Type II), and among its related pathways are Cytoskeletal Signaling and Cytoskeleton remodeling Neurofilaments. Affiliated tissues include tongue, and related mouse phenotypes are craniofacial and digestive/alimentary.

Related Diseases for Median Rhomboid Glossitis

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Diseases related to Median Rhomboid Glossitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 44)
idRelated DiseaseScoreTop Affiliating Genes
1glossitis11.2
2geographic tongue10.6
3fissured tongue10.6
4candidiasis10.6
5pachyonychia congenita10.4
6hairy tongue10.4
7sarcoma10.4
8nasal cavity cancer10.2KRT6A, KRT6B
9tonsil cancer10.2KRT6A, KRT6B
10obesity with impaired prohormone processing10.2KRT16, KRT6A
11obesity bmiq1210.2KRT16, KRT6A
12hypertensive heart disease10.2KRT16, KRT6A
13tongue cancer10.1KRT16, KRT17
14pili torti10.1KRT16, KRT17
15sclerosteosis 110.1KRT16, KRT17
16palmoplantar keratoderma, epidermolytic10.1KRT16, KRT17
17bowenoid papulosis10.1KRT16, KRT17
18keratoconjunctivitis10.1KRT16, KRT17
19white sponge nevus 110.1KRT16, KRT6A, KRT6B
20common peroneal nerve lesion10.0B2M, TTR
21arterial calcification of infancy10.0KRT16, KRT17
22tic disorder10.0B2M, TTR
23steatocystoma multiplex10.0KRT16, KRT17, KRT6B
24uterine corpus adenofibroma10.0B2M, TTR
25epidermolytic hyperkeratosis10.0KRT16, KRT17, KRT6A
26monilethrix10.0KRT16, KRT17, KRT6A
27amyloidosis beta2m10.0B2M, TTR
28palmoplantar keratoderma, nonepidermolytic10.0KRT16, KRT17
29nerve plexus neoplasm10.0B2M, TTR
30alopecia-mental retardation syndrome 310.0B2M, TTR
31rectosigmoid cancer10.0B2M, THEM5
32small intestine lymphoma10.0KRT16, KRT17, KRT6A
33peripheral nervous system neoplasm10.0B2M, TTR
34amyloidosis, familial visceral9.9B2M, TTR
35mechanical entropion9.9B2M, CD4
36chronic lymphocytic leukemia9.9B2M, TTR
37foxg1 syndrome9.9KRT16, KRT17, KRT6A, KRT6B
38brugada syndrome9.9KRT16, KRT17, KRT6A, KRT6B
39atypical lipomatous tumor9.8B2M, THEM5, TTR
40conventional central osteosarcoma9.8CD4, KRT16
41hydrocele9.8B2M, CD4
42glossopharyngeal nerve disease9.7KRT16, KRT17, KRT6A, KRT6B, TTR
43central pontine myelinolysis9.6B2M, CD4
44familiar ovarian carcinoma8.9B2M, CD4, KRT16, KRT17, KRT6A, KRT6B

Graphical network of the top 20 diseases related to Median Rhomboid Glossitis:



Diseases related to median rhomboid glossitis

Symptoms for Median Rhomboid Glossitis

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Drugs & Therapeutics for Median Rhomboid Glossitis

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Median Rhomboid Glossitis

Genetic Tests for Median Rhomboid Glossitis

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Anatomical Context for Median Rhomboid Glossitis

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MalaCards organs/tissues related to Median Rhomboid Glossitis:

33
Tongue

Animal Models for Median Rhomboid Glossitis or affiliated genes

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MGI Mouse Phenotypes related to Median Rhomboid Glossitis:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053829.1KRT16, KRT17, KRT6A, KRT6B
2MP:00053817.6B2M, CD4, KRT16, KRT17, KRT6A, KRT6B
3MP:00053767.2B2M, CD4, KRT16, KRT6A, THEM5, TTR
4MP:00107717.1B2M, CD4, KRT16, KRT17, KRT6A, KRT6B

Publications for Median Rhomboid Glossitis

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Articles related to Median Rhomboid Glossitis:

(show all 43)
idTitleAuthorsYear
1
Median rhomboid glossitis-developmental or candidal? (26523164)
2015
2
Application of the novel method in the diagnosis and treatment of median rhomboid glossitis Candida-associated. (24966760)
2014
3
Diagnostic discussion. Median rhomboid glossitis (MRG). (24579425)
2013
4
Median rhomboid glossitis: a clinical and microbiological study. (21912494)
2011
5
Median rhomboid glossitis. (21446620)
2011
6
The prevalence of median rhomboid glossitis in diabetic patients: a case-control study. (22737518)
2011
7
Hyperplastic candidosis on the palate developed as a 'kissing' lesion from median rhomboid glossitis. (20339702)
2010
8
A classic case of median rhomboid glossitis. (19601454)
2009
9
Median rhomboid glossitis. (17990677)
2007
10
Partial atrophic tongue other than median rhomboid glossitis. (17441970)
2007
11
Pachyonychia congenita associated with median rhomboid glossitis. (17511954)
2007
12
Diagnostic quiz. Case No. 1: median rhomboid glossitis. (17632961)
2006
13
Prevalence of fissured tongue, geographic tongue and median rhomboid glossitis among Israeli adults of different ethnic origins. (15316160)
2004
14
Kaposi's sarcoma of the tongue associated with median rhomboid glossitis in a non-AIDS patient. A case report. (15274372)
2004
15
A case of median rhomboid glossitis. (12773811)
2003
16
Oral pathology quiz #2. Median rhomboid glossitis. (11808366)
2001
17
Cause of median rhomboid glossitis. (8705579)
1996
18
Median rhomboid glossitis and a "kissing" lesion of the palate. (8936507)
1996
19
Median rhomboid glossitis. (8899768)
1996
20
Median rhomboid glossitis. An oral manifestation in patients infected with HIV. (8078660)
1994
21
Squamous cell carcinoma mimicking median rhomboid glossitis region: report of a case. (8509924)
1993
22
Quantitative evaluation of Langerhans cells in median rhomboid glossitis. (1593492)
1992
23
Median rhomboid glossitis: secondary to colonisation of the tongue by Actinomyces (a case report). (1841980)
1991
24
Median rhomboid glossitis: review of a puzzling entity. (2097050)
1990
25
Median rhomboid glossitis. A follow-up study of 16 patients. (3459824)
1986
26
Candida albicans in median rhomboid glossitis. A postmortem study. (3088163)
1986
27
Median rhomboid glossitis in an infant. Report of a case. (3861810)
1985
28
Tobacco smoking and denture wearing as local aetiological factors in median rhomboid glossitis. (6438002)
1984
29
Chronic candidiasis of the rat tongue: a possible model for human median rhomboid glossitis. (6958728)
1982
30
Median rhomboid glossitis caused by Candida? (282562)
1979
31
Median rhomboid glossitis associated with amyloid deposition. (676752)
1978
32
Median rhomboid glossitis: not a misnomer. Review of the literature and histologic study of twenty-eight cases. (366496)
1978
33
Carcinoma arising in the area of median rhomboid glossitis. (1063965)
1976
34
Median rhomboid glossitis. Candidiasis and not a developmental anomaly. (1201190)
1975
35
Median rhomboid glossitis. Case report. (4713826)
1973
36
Median rhomboid glossitis: a developmental anomaly? (5275506)
1971
37
Prevalence of geographic tongue, fissured tongue, median rhomboid glossitis, and hairy tongue among 3,611 Minnesota schoolchildren. (5270895)
1970
38
Median rhomboid glossitis. Case report. (5353692)
1969
39
Incidence of geographic tongue and median rhomboid glossitis in 3,319 Negro college students. (5245682)
1968
40
Median rhomboid glossitis: an atypical variant. (5234276)
1967
41
Median rhomboid glossitis; case reported in an infant. (13125261)
1954
42
The occurrence of Fordyce spots, benign migratory glossitis, median rhomboid glossitis, and fissured tongue in 2,478 dental patients. (13088005)
1953
43
Median rhomboid glossitis; report of a case. (13013723)
1952

Variations for Median Rhomboid Glossitis

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Expression for genes affiliated with Median Rhomboid Glossitis

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Search GEO for disease gene expression data for Median Rhomboid Glossitis.

Pathways for genes affiliated with Median Rhomboid Glossitis

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GO Terms for genes affiliated with Median Rhomboid Glossitis

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Cellular components related to Median Rhomboid Glossitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1intermediate filamentGO:00058829.5KRT16, KRT17, KRT6A, KRT6B
2extracellular exosomeGO:00700627.7B2M, KRT16, KRT17, KRT6A, KRT6B, TTR

Biological processes related to Median Rhomboid Glossitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1intermediate filament cytoskeleton organizationGO:00451049.9KRT16, KRT6A
2keratinizationGO:00314249.3KRT16, KRT17
3morphogenesis of an epitheliumGO:00020099.2KRT16, KRT17, KRT6A
4regulation of defense response to virus by virusGO:00506909.1B2M, CD4
5defense response to Gram-negative bacteriumGO:00508299.0B2M, CD4

Molecular functions related to Median Rhomboid Glossitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1MHC class II protein bindingGO:00422899.5CD4, KRT17
2glycoprotein bindingGO:00019489.3B2M, CD4
3structural constituent of cytoskeletonGO:00052008.9KRT16, KRT17, KRT6A, KRT6B
4structural molecule activityGO:00051988.6KRT16, KRT17, KRT6A, KRT6B

Sources for Median Rhomboid Glossitis

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet