MCID: MDN001
MIFTS: 25

Median Rhomboid Glossitis malady

Gastrointestinal diseases category

Summaries for Median Rhomboid Glossitis

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63Wikipedia, 32MalaCards
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Wikipedia:63 Median rhomboid glossitis (MRG, also known as central papillary atrophy, or glossal central papillary... more...

MalaCards: Median Rhomboid Glossitis, also known as persistent tuberculum impar, is related to pachyonychia congenita and glossitis. An important gene associated with Median Rhomboid Glossitis is KRT6B (keratin 6B), and among its related pathways is Cytoskeletal Signaling. Affiliated tissues include tongue.

Aliases & Classifications for Median Rhomboid Glossitis

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8Disease Ontology, 10DISEASES, 60UMLS, 27ICD9CM, 56SNOMED-CT, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Gastrointestinal diseases


Aliases & Descriptions:

median rhomboid glossitis 8 10
persistent tuberculum impar 8


External Ids:

Disease Ontology8 DOID:14111
ICD9CM27 529.2
SNOMED-CT56 7522008
ICD1025 K14.2

Related Diseases for Median Rhomboid Glossitis

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17GeneCards, 18GeneDecks
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Diseases related to Median Rhomboid Glossitis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 12)
idRelated DiseaseScoreTop Affiliating Genes
1pachyonychia congenita30.5KRT6A, KRT6B
2glossitis11.1
3fissured tongue10.6
4candidiasis10.5
5benign migratory glossitis10.3
6hairy tongue10.3
7kaposi's sarcoma10.3
8sarcoma10.3
9squamous cell carcinoma10.3
10hereditary mucosal leukokeratosis10.0KRT6A, KRT6B
11keratosis10.0KRT6A, KRT6B
12monilethrix10.0KRT6A, KRT6B

Graphical network of diseases related to Median Rhomboid Glossitis:



Diseases related to median rhomboid glossitis

Clinical Features for Median Rhomboid Glossitis

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Drugs & Therapeutics for Median Rhomboid Glossitis

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Median Rhomboid Glossitis

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Anatomical Context for Median Rhomboid Glossitis

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32MalaCards
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MalaCards organs/tissues related to Median Rhomboid Glossitis:

32
Tongue

Animal Models for Median Rhomboid Glossitis or affiliated genes

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Publications for Median Rhomboid Glossitis

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50PubMed
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Articles related to Median Rhomboid Glossitis:

(show all 40)
idTitleAuthorsYear
1
Median rhomboid glossitis: a clinical and microbiological study. (21912494)
2011
2
Median rhomboid glossitis. (21446620)
2011
3
The prevalence of median rhomboid glossitis in diabetic patients: a case-control study. (22737518)
2011
4
Hyperplastic candidosis on the palate developed as a 'kissing' lesion from median rhomboid glossitis. (20339702)
2010
5
A classic case of median rhomboid glossitis. (19601454)
2009
6
Median rhomboid glossitis. (17990677)
2007
7
Partial atrophic tongue other than median rhomboid glossitis. (17441970)
2007
8
Pachyonychia congenita associated with median rhomboid glossitis. (17511954)
2007
9
Diagnostic quiz. Case No. 1: median rhomboid glossitis. (17632961)
2006
10
Prevalence of fissured tongue, geographic tongue and median rhomboid glossitis among Israeli adults of different ethnic origins. (15316160)
2004
11
Kaposi's sarcoma of the tongue associated with median rhomboid glossitis in a non-AIDS patient. A case report. (15274372)
2004
12
A case of median rhomboid glossitis. (12773811)
2003
13
Oral pathology quiz #2. Median rhomboid glossitis. (11808366)
2001
14
Cause of median rhomboid glossitis. (8705579)
1996
15
Median rhomboid glossitis and a "kissing" lesion of the palate. (8936507)
1996
16
Median rhomboid glossitis. (8899768)
1996
17
Median rhomboid glossitis. An oral manifestation in patients infected with HIV. (8078660)
1994
18
Squamous cell carcinoma mimicking median rhomboid glossitis region: report of a case. (8509924)
1993
19
Quantitative evaluation of Langerhans cells in median rhomboid glossitis. (1593492)
1992
20
Median rhomboid glossitis: secondary to colonisation of the tongue by Actinomyces (a case report). (1841980)
1991
21
Median rhomboid glossitis: review of a puzzling entity. (2097050)
1990
22
Median rhomboid glossitis. A follow-up study of 16 patients. (3459824)
1986
23
Candida albicans in median rhomboid glossitis. A postmortem study. (3088163)
1986
24
Median rhomboid glossitis in an infant. Report of a case. (3861810)
1985
25
Tobacco smoking and denture wearing as local aetiological factors in median rhomboid glossitis. (6438002)
1984
26
Chronic candidiasis of the rat tongue: a possible model for human median rhomboid glossitis. (6958728)
1982
27
Median rhomboid glossitis caused by Candida? (282562)
1979
28
Median rhomboid glossitis associated with amyloid deposition. (676752)
1978
29
Median rhomboid glossitis: not a misnomer. Review of the literature and histologic study of twenty-eight cases. (366496)
1978
30
Carcinoma arising in the area of median rhomboid glossitis. (1063965)
1976
31
Median rhomboid glossitis. Candidiasis and not a developmental anomaly. (1201190)
1975
32
Median rhomboid glossitis. Case report. (4713826)
1973
33
Median rhomboid glossitis: a developmental anomaly? (5275506)
1971
34
Prevalence of geographic tongue, fissured tongue, median rhomboid glossitis, and hairy tongue among 3,611 Minnesota schoolchildren. (5270895)
1970
35
Median rhomboid glossitis. Case report. (5353692)
1969
36
Incidence of geographic tongue and median rhomboid glossitis in 3,319 Negro college students. (5245682)
1968
37
Median rhomboid glossitis: an atypical variant. (5234276)
1967
38
Median rhomboid glossitis; case reported in an infant. (13125261)
1954
39
The occurrence of Fordyce spots, benign migratory glossitis, median rhomboid glossitis, and fissured tongue in 2,478 dental patients. (13088005)
1953
40
Median rhomboid glossitis; report of a case. (13013723)
1952

Genetic Variations for Median Rhomboid Glossitis

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Expression for genes affiliated with Median Rhomboid Glossitis

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Median Rhomboid Glossitis

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Pathways for genes affiliated with Median Rhomboid Glossitis

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4Cell Signaling Technology
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Pathways related to Median Rhomboid Glossitis according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.3KRT6B, KRT6A

Compounds for genes affiliated with Median Rhomboid Glossitis

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GO Terms for genes affiliated with Median Rhomboid Glossitis

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16Gene Ontology
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Cellular components related to Median Rhomboid Glossitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1keratin filamentGO:0450959.3KRT6B, KRT6A

Biological processes related to Median Rhomboid Glossitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1ectoderm developmentGO:0073989.3KRT6B, KRT6A

Molecular functions related to Median Rhomboid Glossitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1structural constituent of cytoskeletonGO:0052009.3KRT6B, KRT6A

Products for genes affiliated with Median Rhomboid Glossitis

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Sources for Median Rhomboid Glossitis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet