MCID: MDS022
MIFTS: 46

Mediastinitis malady

Summaries for Mediastinitis

About this section
Sources:
66Wikipedia, 34MalaCards
See all sources

Fully expand this MalaCard

Download this MalaCard
Wikipedia:66 Mediastinitis is inflammation of the tissues in the mid-chest, or mediastinum. It can be either acute or... more...

MalaCards: Mediastinitis is related to tuberculosis and pancreatitis. An important gene associated with Mediastinitis is MPO (myeloperoxidase), and among its related pathways is Selenium Pathway. The compounds cefdinir and cefaclor have been mentioned in the context of this disorder. Affiliated tissues include b cells, lymph node and lung.

Aliases & Classifications for Mediastinitis

About this section
Sources:
9Disease Ontology, 11DISEASES, 63UMLS, 36MeSH, 59SNOMED-CT, 28ICD9CM, 41NCIt
See all sources

Aliases & Descriptions:

mediastinitis 9 11 63


External Ids:

Disease Ontology9 DOID:819
MeSH36 D008480
SNOMED-CT59 47597000
ICD9CM28 519.2
NCIt41 C26827

Related Diseases for Mediastinitis

About this section
Sources:
18GeneCards, 19GeneDecks
See all sources

Graphical network of the top 20 diseases related to Mediastinitis:



Diseases related to mediastinitis

Symptoms for Mediastinitis

About this section

Drugs & Therapeutics for Mediastinitis

About this section
Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials
See all sources

Approved drugs:

Search CenterWatch for Mediastinitis

Drug clinical trials:

Search ClinicalTrials for Mediastinitis

Search NIH Clinical Center for Mediastinitis

Search CenterWatch for Mediastinitis

Genetic Tests for Mediastinitis

About this section

Anatomical Context for Mediastinitis

About this section
Sources:
34MalaCards
See all sources

MalaCards organs/tissues related to Mediastinitis:

34
B cells, Lymph node, Lung, Heart, Thyroid, Myeloid, Bone, T cells, Liver, Breast, Skin, Tonsil, Colon, Bone marrow, Thymus, Trachea, Spinal cord, Prostate, Pancreas, Brain, Monocytes, Ovary, Spleen, Kidney, Testes, Pituitary

Animal Models for Mediastinitis or affiliated genes

About this section

Publications for Mediastinitis

About this section
Sources:
53PubMed
See all sources

Articles related to Mediastinitis:

(show top 50)    (show all 1724)
idTitleAuthorsYear
1
Clinical utility and economic impact of conventional transbronchial needle aspiration of mediastinal lymphadenopathies in bronchogenic carcinoma. (23083635)
2013
2
Mediastinal goiter presenting with ventricular tachycardia. (22302698)
2013
3
Mediastinal hemangioma: Masquerading as pleural effusion. (24347874)
2013
4
Zygomycotic Mediastinal Lymphadenitis in Beef Cattle with Ruminal Tympany. (24018826)
2013
5
Primary mediastinal large B-cell lymphoma segregating in a family: exome sequencing identifies MLL as a candidate predisposition gene. (23457195)
2013
6
Embryonal rhabdomyosarcoma arising from a mediastinal teratoma: an unusual case report. (23487585)
2013
7
Probable initial pulmonary lymphangioleiomyomatosis and mediastinal lymphangioleiomyoma. (24268918)
2013
8
Isolated mediastinal amyloidosis mimicking a neoplastic lesion. (23585190)
2013
9
Mediastinitis: mortality rate comparing single-stage surgical approach and preconditioning of wound. (23939316)
2013
10
Mediastinal lymphangioma treated using endobronchial ultrasound-guided transbronchial needle aspiration. (23018866)
2012
11
Fibrosing mediastinitis as a cause of right claudication. (21562863)
2012
12
Combined spontaneous contralateral pneumothorax and post-pneumonectomy mediastinal shift-associated dextrocardia. (21243579)
2011
13
Mediastinal epithelioid hemangioendothelioma mimicking a teratoma. (21492982)
2011
14
Isolated mediastinal myeloid sarcoma successfully treated with chemoradiotherapy followed by unrelated allogeneic stem cell transplantation. (22185993)
2011
15
A case of an elderly patient treated for descending necrotizing mediastinitis. (22231792)
2011
16
An aortic root pseudoaneurysm that developed after implantation of a rectus abdominis muscle flap to treat an MRSA mediastinitis: a case report. (20190716)
2010
17
Two cases of mediastinal gray zone lymphoma. (21123972)
2010
18
Images for surgeons. A case of matured mediastinal teratoma complicated by cardiac tamponade: an unusual aetiology. (21061752)
2010
19
Iniencephaly with mediastinal bronchogenic cyst: A case report. (22439066)
2010
20
Mediastinal mature cystic teratoma perforating into the lung. (20876619)
2010
21
Influence of suboptimal treatment in patients with mediastinal primary nonseminomatous germ cell tumors. (20185939)
2010
22
Severe deep neck space infections and mediastinitis of odontogenic origin: clinical relevance and implications for diagnosis and treatment. (18607917)
2009
23
Primary mediastinal large B-cell lymphoma in HIV: report of two cases. (19669223)
2009
24
The role of omental transposition for the management of postoperative mediastinitis: a case series. (19236690)
2009
25
Mediastinal solitary fibrous tumor with right diaphragm invasion: report of a case. (19319642)
2009
26
Multidrug-resistant Klebsiella pneumoniae mediastinitis safely and effectively treated with prolonged administration of tigecycline. (18540810)
2008
27
Unusual features of malignant pleural mesothelioma metastatic to the mediastinal lymph nodes. (18301236)
2008
28
Mediastinal lymphatic drainage from pulmonary lobe based on CT observations of histoplasmosis: implications for minimal N2 disease of non-small-cell lung cancer. (17952543)
2007
29
High expression of several tyrosine kinases and activation of the PI3K/AKT pathway in mediastinal large B cell lymphoma reveals further similarities to Hodgkin lymphoma. (17375124)
2007
30
Sigmoid colon cancer with mediastinal lymph node metastases. (18050829)
2007
31
Cold agglutinin disease revealing mediastinal seminoma. (17449873)
2007
32
Acute suppurative thyroiditis extending to descending necrotizing mediastinitis and pericarditis. (17381365)
2007
33
Mediastinal Castleman disease mimicking mediastinal pulmonary sequestration. (16077341)
2005
34
Acute mediastinitis resulting from an unsuspected fish bone--case report. (15875620)
2005
35
Calcified metastatic mediastinal lymph nodes from mucinous breast adenocarcinoma. (14566424)
2004
36
Congenital diaphragmatic eventration as a cause of anterior mediastinal mass in the children: imaging modalities and literature review. (15186890)
2004
37
Primary mediastinal B-cell lymphoma: hypermutation of the BCL6 gene targets motifs different from those in diffuse large B-cell and follicular lymphomas. (15377470)
2004
38
Cushing's syndrome with mediastinal lipomatosis. (15322612)
2004
39
Usefulness of routine epicardial pacing wire culture for early prediction of poststernotomy mediastinitis. (15528721)
2004
40
Pathobiology of primary mediastinal B-cell lymphoma. (15202521)
2003
41
Critical care transesophageal endosonography and guided fine-needle aspiration for diagnosis and management of posterior mediastinitis. (12545005)
2003
42
Role of radiation therapy in the management of primary mediastinal large B-cell lymphoma (PMLBL). (12553345)
2002
43
Expression of hMLH1 and hMSH2 and assessment of microsatellite instability in testicular and mediastinal germ cell tumours. (11719586)
2001
44
Preoperative embolization in surgical treatment of mediastinal hemangiopericytoma. (10750792)
2000
45
Posterior mediastinal capillary hemangioma with extradural extension resembling neuroblastoma. (10398787)
1999
46
Transcription of the nude gene (WHN) in human normal organs and mediastinal and pulmonary tumors. (10483588)
1999
47
Mediastinal bronchogenic cyst manifesting as a catastrophic myocardial infarction. (10391298)
1999
48
A patient with a relapse of myasthenia gravis after a 13-year remission following successful treatment by mediastinal irradiation and corticosteroid therapy]. (7605688)
1995
49
Mediastinal mass with acute leukemia. Myeloblastoma masquerading as lymphoblastic lymphoma. (6937159)
1981
50
Mediastinal extramedullary plasmacytoma. (7375991)
1980

Variations for Mediastinitis

About this section

Expression for genes affiliated with Mediastinitis

About this section
Sources:
2BioGPS, 16Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Mediastinitis

Search GEO for disease gene expression data for Mediastinitis.

Pathways for genes affiliated with Mediastinitis

About this section
Sources:
51PathCards, 39NCBI BioSystems Database
See all sources

Pathways related to Mediastinitis according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
thioredoxin pathway39
9.1CRP, MPO

Compounds for genes affiliated with Mediastinitis

About this section
Sources:
46Novoseek, 12DrugBank, 3BitterDB, 52PharmGKB, 30IUPHAR, 25HMDB, 62Tocris Bioscience
See all sources

Compounds related to Mediastinitis according to GeneCards/GeneDecks:

(show top 50)    (show all 53)
idCompoundScoreTop Affiliating Genes
1cefdinir46 1210.9MPO, LACTB
2cefaclor46 1210.9LACTB, MPO
3ampicillin46 1210.8LACTB, MPO
4linezolid46 1210.8F5, LACTB
5nafamostat mesilate469.8F5, MPO
6cefotaxime46 1210.8F5, LACTB
7vancomycin46 1210.8LACTB, F5
8bivalirudin46 1210.8MPO, F5
9taurine chloramine469.7MPO, F5
10erythromycin46 3 52 1212.7MPO, LACTB
11ofloxacin46 3 1211.7LACTB, F5
12penicillin469.7F5, LACTB
13ciprofloxacin46 52 1211.7LACTB, F5
14fluorescein46 1210.7F5, MPO
15dextran sulfate469.7F5, MPO
16kininogen469.6F5, MPO
17aopp469.6CRP, MPO
18azithromycin46 1210.5LACTB, CRP
19d penicillamine469.5CRP, MPO
20sulfasalazine30 46 52 1212.5CRP, MPO
218-isoprostane469.5MPO, CRP
22methacholine46 52 1211.5CRP, MPO
23gabexate mesilate469.4F5, CRP
24convulxin469.4CRP, F5
25tibolone469.4F5, CRP
26clozapine46 30 52 1212.4CRP, MPO
27vitamin b6469.4CRP, F5
28prednisolone46 30 1211.3CRP, MPO
29metformin46 52 1211.3F5, CRP
30uric acid46 2510.3F5, CRP
31homocysteine46 2510.3F5, CRP
32p002469.3CRP, F5
33atorvastatin46 52 30 25 1213.2F5, CRP
34citrate469.2CRP, F5
35simvastatin46 52 62 30 25 1214.1F5, CRP
36endotoxin469.1F5, CRP
37folate469.0F5, CRP
38chloramphenicol46 3 52 1212.0CRP, LACTB, MPO
39ceftriaxone46 1210.0F5, CRP, LACTB
40vitamin b12469.0F5, CRP, MPO
41malondialdehyde469.0MPO, CRP, F5
42polyethylene glycol469.0F5, CRP, MPO
43cyclophosphamide46 52 1210.9MPO, CRP, F5
44prostacyclin468.9CRP, F5
45ascorbic acid46 259.9F5, CRP, MPO
46lactate468.9F5, CRP, MPO
47creatinine468.9F5, CRP, MPO
48serine468.8F5, LACTB, MPO
49vegf468.8MPO, CRP, F5
50aspirin46 52 30 2511.7F5, CRP

GO Terms for genes affiliated with Mediastinitis

About this section
Sources:
17Gene Ontology
See all sources

Cellular components related to Mediastinitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular spaceGO:0056158.5F5, CRP, MPO

Biological processes related to Mediastinitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1agingGO:0075689.1CRP, MPO

Products for genes affiliated with Mediastinitis

About this section
  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Mediastinitis

About this section
4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet