MCID: MDL002
MIFTS: 37

Medulloepithelioma malady

Neuronal diseases, Cancer diseases, Rare diseases categories

Aliases & Classifications for Medulloepithelioma

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Sources:
9Disease Ontology, 11DISEASES, 47Orphanet, 60UMLS, 33MeSH, 55SNOMED-CT, 38NCIt, 61UMLS via Orphanet
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Medulloepithelioma, Aliases & Descriptions:

Name: Medulloepithelioma 9 11 47 60
Medulloepithelioma, Central Nervous System 9
 
Medulloepithelioma Nos 9
Diktyoma, Malignant 9


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases, Rare diseases
Anatomical: Neuronal diseases


Characteristics (Orphanet epidemiological data):

47
medulloepithelioma:
Inheritance: Not applicable; Age of onset: Childhood,Infancy


External Ids:

Disease Ontology9 DOID:4790
MeSH33 D018242
SNOMED-CT55 189932005, 39005004
Orphanet47 251883
UMLS via Orphanet61 C0334596

Summaries for Medulloepithelioma

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Wikipedia:63 Medulloepithelioma is a rare, primitive, fast-growing brain tumour thought to stem from cells of the... more...

MalaCards based summary: Medulloepithelioma, also known as medulloepithelioma, central nervous system, is related to ependymoma and malignant glioma. An important gene associated with Medulloepithelioma is NES (nestin), and among its related pathways is Cytoplasmic microtubules. The compounds streptozotocin and mucicarmine have been mentioned in the context of this disorder. Affiliated tissues include eye, brain and retina, and related mouse phenotype nervous system.

Related Diseases for Medulloepithelioma

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Diseases related to Medulloepithelioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 54)
idRelated DiseaseScoreTop Affiliating Genes
1ependymoma30.2SYP, NES
2malignant glioma29.8TERT, NES, SYP
3adenoma29.3TERT, NES, SYP, KRT20
4adenocarcinoma29.3KRT20, SYP, NES, TERT
5intraocular medulloepithelioma10.6
6cerebritis10.4
7subependymal giant cell astrocytoma10.4SYP
8dysembryoplastic neuroepithelial tumor10.4SYP
9ganglioglioma10.4SYP
10pleuropulmonary blastoma10.3
11blastoma10.3
12retinitis10.2
13malignant peripheral nerve sheath tumor10.2TERT, NES
14stroke, ischemic10.2NES, INA
15teratoma10.2NES, TERT
16uveitis10.1
17hemangioblastoma10.1SYP, NES
18brain cancer10.1SYP, NES
19pilocytic astrocytoma10.1SYP, NES
20tuberous sclerosis10.1SYP, NES
21glioblastoma multiforme10.1NES, TERT
22pituitary adenoma10.0NES, SYP
23lung cancer10.0SYP, TERT
24meningioma, familial10.0SYP, TERT
25merkel cell carcinoma10.0SYP, KRT20
26tubular adenocarcinoma10.0KRT20, SYP
27large cell carcinoma10.0SYP, KRT20
28tumor predisposition syndrome10.0
29retinoblastoma10.0
30cataract10.0
31persistent hyperplastic primary vitreous10.0
32ependymoblastoma10.0
33mediastinitis10.0
34melanoma10.0
35pineoblastoma10.0
36retinal detachment10.0
37rhabdomyosarcoma10.0
38cholangiocarcinoma10.0KRT20, TERT
39amyotrophic lateral sclerosis 110.0SYP, NES
40oxyphilic adenoma10.0SYP, KRT20
41bladder cancer, somatic10.0KRT20, TERT
42neuroendocrine tumor10.0KRT20, SYP
43pheochromocytoma10.0SYP, TERT
44papillary carcinoma10.0KRT20, SYP
45carcinoid syndrome9.9KRT20, SYP
46astrocytoma9.9SYP, NES, INA
47pancreatic cancer9.9SYP, NES, TERT
48medulloblastoma9.9TERT, NES, SYP
49lung cancer susceptibility 39.8KRT20, TERT
50small cell cancer of the lung, somatic9.8KRT20, SYP

Graphical network of the top 20 diseases related to Medulloepithelioma:



Diseases related to medulloepithelioma

Symptoms for Medulloepithelioma

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Drugs & Therapeutics for Medulloepithelioma

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Drug clinical trials:

Search ClinicalTrials for Medulloepithelioma

Search NIH Clinical Center for Medulloepithelioma

Genetic Tests for Medulloepithelioma

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Anatomical Context for Medulloepithelioma

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MalaCards organs/tissues related to Medulloepithelioma:

31
Eye, Brain, Retina, Bone, Spinal cord, Kidney, Pons

Animal Models for Medulloepithelioma or affiliated genes

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MGI Mouse Phenotypes related to Medulloepithelioma:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00036318.1SYP, NES, INA, TERT

Publications for Medulloepithelioma

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Articles related to Medulloepithelioma:

(show top 50)    (show all 153)
idTitleAuthorsYear
1
Pigmented malignant teratoid medulloepithelioma of ciliary body - An extremely rare intraocular tumor in adult. (25278807)
2014
2
Unusual occurrence of supratentorial medulloepithelioma in a young female. (25002766)
2014
3
Peripheral medulloepithelioma: a rare tumor with a potential target therapy. (24559248)
2014
4
Ciliary body medulloepithelioma in an adult. (23218809)
2013
5
Malignant teratoid medulloepithelioma with retinoblastic and rhabdomyoblastic differentiation. (23791415)
2013
6
Ciliary body medulloepithelioma associated with pleuropulmonary blastoma. (23613510)
2013
7
Ciliary body medulloepithelioma in a 10-year-old boy. (22776925)
2012
8
The masquerades of a childhood ciliary body medulloepithelioma: a case of chronic uveitis, cataract, and secondary glaucoma. (22606494)
2012
9
Ciliary body medulloepithelioma with neoplastic cyclitic membrane imaging with fluorescein angiography and ultrasound biomicroscopy. (21505878)
2011
10
Medulloepithelioma of the optic disc. (21676432)
2011
11
Curative treatment for central nervous system medulloepithelioma despite residual disease after resection. Report of two cases treated according to the GPHO Protocol HIT 2000 and review of the literature. (22037651)
2011
12
Malignant non-teratoid medulloepithelioma of the optic nerve with intraocular extension. (20497433)
2010
13
Conservative surgical treatment of medulloepithelioma of the ciliary body. (20212214)
2010
14
Malignant medulloepithelioma of optic nerve head. (18525470)
2008
15
Diffuse retinal involvement in malignant nonteratoid medulloepithelioma of ciliary body in an adult. (16087851)
2005
16
Echographic features of a case of malignant intraocular medulloepithelioma. (15615759)
2005
17
Immunohistochemical characterization of a malignant intraocular teratoid medulloepithelioma in a cockatiel. (15644102)
2005
18
What's your diagnosis? Ciliary body medulloepithelioma. (15724891)
2005
19
Medulloepithelioma of the optic nerve. (14974835)
2004
20
Intracerebral medulloepithelioma with a long survival. (12365722)
2002
21
Pigmented medulloepithelioma of the ciliary body. (11831926)
2002
22
Malignant teratoid medulloepithelioma: clinical-echographic-histopathologic correlation. (11753262)
2001
23
Iris neovascularization in children as a manifestation of underlying medulloepithelioma. (11495310)
2001
24
Sellar and suprasellar medulloepithelioma. (11550774)
2001
25
Bilateral ectopia lentis as a presenting feature of medulloepithelioma. (11507586)
2001
26
Presumed bilateral medulloepithelioma. (11231783)
2001
27
Successful therapy in a child with a congenital peripheral medulloepithelioma and disruption of hindquarter development. (10206465)
1999
28
Malignant nonteratoid medulloepithelioma of the ciliary body in an adult. (9544630)
1998
29
Medulloepithelioma of the optic nerve head. (9338683)
1997
30
Immunohistochemistry of medulloepithelioma and neural tube. (9353831)
1997
31
Medulloepithelioma in a cat. (9560905)
1996
32
Non-rubeotic angle-closure glaucoma associated with ciliary medulloepithelioma. (8876394)
1996
33
Basic fibroblast growth factor and somatomedin C in human medulloepithelioma. (1855180)
1991
34
Medulloepithelioma of the ciliary body. (1927327)
1991
35
Malignant teratoid medulloepithelioma of the ciliary body. (2150850)
1990
36
Glioneuroma associated with colobomatous dysplasia of the anterior uvea and retina. A case simulating medulloepithelioma. (2622623)
1989
37
Medulloepithelioma (diktyoma). (3056510)
1988
38
Medulloepithelioma: MRI appearances. (3248094)
1988
39
Medulloepithelioma of the ciliary body. (3841866)
1985
40
Malignant teratoid medulloepithelioma manifesting as a black epibulbar mass with expulsive hemorrhage. (6487119)
1984
41
Spinal cord medulloepithelioma in a dog. (6501052)
1984
42
Cerebral medulloepithelioma with bone, cartilage, and striated muscle. Light microscopic and immunohistochemical study. (6302229)
1983
43
Medulloepithelioma diagnosed by ultrasound and vitreous aspirate. Electron microscopic observations. (6677853)
1983
44
Intraocular medulloepithelioma in a 79-year-old man. (7177573)
1982
45
Fine structure of medulloepithelioma. (886367)
1977
46
Electron microscopic diagnosis of medulloepithelioma. (1115200)
1975
47
Malignant teratoid medulloepithelioma of the optic nerve. (4827430)
1974
48
Primary malignant medulloepithelioma of the retinal stalk. (4206617)
1974
49
Medulloepithelioma: definition of an entity. (5060129)
1972
50
An autopsy case of metastasizing mediastinal medulloepithelioma. (12998897)
1952

Variations for Medulloepithelioma

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Expression for genes affiliated with Medulloepithelioma

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Search GEO for disease gene expression data for Medulloepithelioma.

Pathways for genes affiliated with Medulloepithelioma

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Pathways related to Medulloepithelioma according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes

Compounds for genes affiliated with Medulloepithelioma

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Sources:
43Novoseek, 28IUPHAR, 24HMDB, 12DrugBank, 59Tocris Bioscience
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Compounds related to Medulloepithelioma according to GeneCards Suite gene sharing:

(show all 18)
idCompoundScoreTop Affiliating Genes
1streptozotocin439.7NES, SYP
2mucicarmine439.7KRT20, SYP
3b 723439.7SYP, KRT20
4ganglioside439.6SYP, NES
5hematoxylin439.6KRT20, SYP
6kainate43 2810.6SYP, NES
7choline43 24 1211.5SYP, NES
8formaldehyde43 2410.3SYP, KRT20
9progesterone43 28 59 24 1213.2KRT20, SYP, NES
10sucrose43 24 1211.1KRT20, SYP
11nitric oxide43 24 1211.0TERT, NES, SYP
12testosterone43 59 24 1212.0TERT, SYP, KRT20
13lipid438.9SYP, NES, TERT
14paraffin438.7KRT20, SYP, NES, TERT
15vegf438.7TERT, NES, SYP, KRT20
16estrogen438.7KRT20, SYP, NES, TERT
17tyrosine438.6KRT20, SYP, NES, TERT
18retinoic acid43 249.3TERT, INA, NES, SYP

GO Terms for genes affiliated with Medulloepithelioma

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Cellular components related to Medulloepithelioma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1intermediate filamentGO:00058829.5KRT20, NES

Molecular functions related to Medulloepithelioma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1structural constituent of cytoskeletonGO:00052009.1KRT20, INA

Products for genes affiliated with Medulloepithelioma

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  • Kits and Assays

Sources for Medulloepithelioma

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet