MCID: MDL002
MIFTS: 43

Medulloepithelioma malady

Neuronal diseases, Cancer diseases, Rare diseases categories
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Summaries for Medulloepithelioma

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Wikipedia:65 Medulloepithelioma is a rare, primitive, fast-growing brain tumour thought to stem from cells of the... more...

MalaCards based summary: Medulloepithelioma, also known as medulloepithelioma, central nervous system, is related to ependymoma and malignant glioma. An important gene associated with Medulloepithelioma is NES (nestin), and among its related pathways is Cytoplasmic microtubules. The compounds streptozotocin and mucicarmine have been mentioned in the context of this disorder. Affiliated tissues include eye, brain and retina, and related mouse phenotype nervous system.

Aliases & Classifications for Medulloepithelioma

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Sources:
8Disease Ontology, 10DISEASES, 48Orphanet, 62UMLS, 57SNOMED-CT, 39NCIt, 34MeSH, 63UMLS via Orphanet
See all sources

Medulloepithelioma, Aliases & Descriptions:

Name: Medulloepithelioma 8 10 48 62
Medulloepithelioma, Central Nervous System 8
 
Medulloepithelioma Nos 8
Diktyoma, Malignant 8


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases, Rare diseases
Anatomical: Neuronal diseases


Characteristics (Orphanet epidemiological data):

48
medulloepithelioma:
Inheritance: Sporadic; Age of onset: Neonatal/infancy


External Ids:

Disease Ontology8 DOID:4790
SNOMED-CT57 39005004, 189932005
MeSH34 D018242
UMLS via Orphanet63 C0334596

Related Diseases for Medulloepithelioma

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Diseases related to Medulloepithelioma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 56)
idRelated DiseaseScoreTop Affiliating Genes
1ependymoma30.2SYP, NES
2malignant glioma29.8TERT, NES, SYP
3adenoma29.3TERT, NES, KRT20, SYP
4adenocarcinoma29.3TERT, NES, SYP, KRT20
5intraocular medulloepithelioma10.6
6cerebritis10.4
7subependymal giant cell astrocytoma10.4SYP
8dysembryoplastic neuroepithelial tumor10.4SYP
9ganglioglioma10.4SYP
10blastoma10.2
11pleuropulmonary blastoma10.2
12retinitis10.2
13malignant peripheral nerve sheath tumor10.2TERT, NES
14stroke, ischemic10.2NES, INA
15teratoma10.2NES, TERT
16hemangioblastoma10.1SYP, NES
17uveitis10.1
18brain cancer10.1NES, SYP
19pilocytic astrocytoma10.1SYP, NES
20tuberous sclerosis10.1SYP, NES
21glioblastoma multiforme10.1TERT, NES
22pituitary adenoma10.1NES, SYP
23non-small cell lung carcinoma10.0TERT, SYP
24meningioma10.0SYP, TERT
25merkel cell carcinoma10.0KRT20, SYP
26tubular adenocarcinoma10.0KRT20, SYP
27large cell carcinoma10.0SYP, KRT20
28cholangiocarcinoma10.0TERT, KRT20
29amyotrophic lateral sclerosis type 1410.0NES, SYP
30oxyphilic adenoma10.0SYP, KRT20
31neuroendocrine carcinoma10.0KRT20, SYP
32cataract10.0
33ependymoblastoma10.0
34mediastinitis10.0
35melanoma10.0
36pineoblastoma10.0
37retinal detachment10.0
38retinoblastoma10.0
39rhabdomyosarcoma10.0
40tumor predisposition syndrome10.0
41persistent hyperplastic primary vitreous10.0
42bladder carcinoma10.0KRT20, TERT
43neuroendocrine tumor10.0SYP, KRT20
44pheochromocytoma10.0TERT, SYP
45papillary carcinoma10.0SYP, KRT20
46carcinoid syndrome9.9SYP, KRT20
47astrocytoma9.9INA, SYP, NES
48pancreatic cancer9.9TERT, NES, SYP
49medulloblastoma9.9NES, TERT, SYP
50lung adenocarcinoma9.8KRT20, TERT

Graphical network of the top 20 diseases related to Medulloepithelioma:



Diseases related to medulloepithelioma

Symptoms for Medulloepithelioma

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Drugs & Therapeutics for Medulloepithelioma

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Drug clinical trials:

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Search NIH Clinical Center for Medulloepithelioma

Genetic Tests for Medulloepithelioma

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Anatomical Context for Medulloepithelioma

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MalaCards organs/tissues related to Medulloepithelioma:

32
Eye, Brain, Retina, Bone, Spinal cord, Kidney, Pons

Animal Models for Medulloepithelioma or affiliated genes

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MGI Mouse Phenotypes related to Medulloepithelioma:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00036318.1SYP, NES, INA, TERT

Publications for Medulloepithelioma

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Articles related to Medulloepithelioma:

(show top 50)    (show all 148)
idTitleAuthorsYear
1
Pigmented malignant teratoid medulloepithelioma of ciliary body - An extremely rare intraocular tumor in adult. (25278807)
2014
2
Unusual occurrence of supratentorial medulloepithelioma in a young female. (25002766)
2014
3
Peripheral medulloepithelioma: a rare tumor with a potential target therapy. (24559248)
2014
4
Ciliary body medulloepithelioma in an adult. (23218809)
2013
5
Malignant teratoid medulloepithelioma with retinoblastic and rhabdomyoblastic differentiation. (23791415)
2013
6
Ciliary body medulloepithelioma associated with pleuropulmonary blastoma. (23613510)
2013
7
Ciliary body medulloepithelioma in a 10-year-old boy. (22776925)
2012
8
The masquerades of a childhood ciliary body medulloepithelioma: a case of chronic uveitis, cataract, and secondary glaucoma. (22606494)
2012
9
Ciliary body medulloepithelioma with neoplastic cyclitic membrane imaging with fluorescein angiography and ultrasound biomicroscopy. (21505878)
2011
10
Medulloepithelioma of the optic disc. (21676432)
2011
11
Curative treatment for central nervous system medulloepithelioma despite residual disease after resection. Report of two cases treated according to the GPHO Protocol HIT 2000 and review of the literature. (22037651)
2011
12
Malignant non-teratoid medulloepithelioma of the optic nerve with intraocular extension. (20497433)
2010
13
Conservative surgical treatment of medulloepithelioma of the ciliary body. (20212214)
2010
14
Malignant medulloepithelioma of optic nerve head. (18525470)
2008
15
Diffuse retinal involvement in malignant nonteratoid medulloepithelioma of ciliary body in an adult. (16087851)
2005
16
Echographic features of a case of malignant intraocular medulloepithelioma. (15615759)
2005
17
Immunohistochemical characterization of a malignant intraocular teratoid medulloepithelioma in a cockatiel. (15644102)
2005
18
What's your diagnosis? Ciliary body medulloepithelioma. (15724891)
2005
19
Medulloepithelioma of the optic nerve. (14974835)
2004
20
Intracerebral medulloepithelioma with a long survival. (12365722)
2002
21
Pigmented medulloepithelioma of the ciliary body. (11831926)
2002
22
Malignant teratoid medulloepithelioma: clinical-echographic-histopathologic correlation. (11753262)
2001
23
Iris neovascularization in children as a manifestation of underlying medulloepithelioma. (11495310)
2001
24
Sellar and suprasellar medulloepithelioma. (11550774)
2001
25
Bilateral ectopia lentis as a presenting feature of medulloepithelioma. (11507586)
2001
26
Presumed bilateral medulloepithelioma. (11231783)
2001
27
Successful therapy in a child with a congenital peripheral medulloepithelioma and disruption of hindquarter development. (10206465)
1999
28
Malignant nonteratoid medulloepithelioma of the ciliary body in an adult. (9544630)
1998
29
Medulloepithelioma of the optic nerve head. (9338683)
1997
30
Immunohistochemistry of medulloepithelioma and neural tube. (9353831)
1997
31
Medulloepithelioma in a cat. (9560905)
1996
32
Non-rubeotic angle-closure glaucoma associated with ciliary medulloepithelioma. (8876394)
1996
33
Basic fibroblast growth factor and somatomedin C in human medulloepithelioma. (1855180)
1991
34
Medulloepithelioma of the ciliary body. (1927327)
1991
35
Malignant teratoid medulloepithelioma of the ciliary body. (2150850)
1990
36
Glioneuroma associated with colobomatous dysplasia of the anterior uvea and retina. A case simulating medulloepithelioma. (2622623)
1989
37
Medulloepithelioma: MRI appearances. (3248094)
1988
38
Medulloepithelioma of the ciliary body. (3841866)
1985
39
Malignant teratoid medulloepithelioma manifesting as a black epibulbar mass with expulsive hemorrhage. (6487119)
1984
40
Spinal cord medulloepithelioma in a dog. (6501052)
1984
41
Cerebral medulloepithelioma with bone, cartilage, and striated muscle. Light microscopic and immunohistochemical study. (6302229)
1983
42
Medulloepithelioma diagnosed by ultrasound and vitreous aspirate. Electron microscopic observations. (6677853)
1983
43
Intraocular medulloepithelioma in a 79-year-old man. (7177573)
1982
44
Fine structure of medulloepithelioma. (886367)
1977
45
Electron microscopic diagnosis of medulloepithelioma. (1115200)
1975
46
Malignant teratoid medulloepithelioma of the optic nerve. (4827430)
1974
47
Primary malignant medulloepithelioma of the retinal stalk. (4206617)
1974
48
Medulloepithelioma: definition of an entity. (5060129)
1972
49
Cerebral medulloepithelioma. Case report. (6065130)
1967
50
An autopsy case of metastasizing mediastinal medulloepithelioma. (12998897)
1952

Variations for Medulloepithelioma

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Expression for genes affiliated with Medulloepithelioma

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Expression patterns in normal tissues for genes affiliated with Medulloepithelioma

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Pathways for genes affiliated with Medulloepithelioma

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Pathways related to Medulloepithelioma according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
Cytoskeleton remodeling Neurofilaments60
9.2NES, INA

Compounds for genes affiliated with Medulloepithelioma

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Sources:
44Novoseek, 28IUPHAR, 24HMDB, 11DrugBank, 61Tocris Bioscience
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Compounds related to Medulloepithelioma according to GeneCards/GeneDecks:

(show all 18)
idCompoundScoreTop Affiliating Genes
1streptozotocin449.7NES, SYP
2mucicarmine449.7KRT20, SYP
3b 723449.7SYP, KRT20
4ganglioside449.6SYP, NES
5hematoxylin449.6KRT20, SYP
6kainate44 2810.6SYP, NES
7choline44 24 1111.5SYP, NES
8formaldehyde44 2410.3SYP, KRT20
9progesterone44 28 61 24 1113.2KRT20, SYP, NES
10sucrose44 24 1111.1KRT20, SYP
11nitric oxide44 24 1111.0TERT, NES, SYP
12testosterone44 61 24 1112.0TERT, SYP, KRT20
13lipid448.9SYP, NES, TERT
14paraffin448.7KRT20, SYP, NES, TERT
15vegf448.7TERT, NES, SYP, KRT20
16estrogen448.7KRT20, SYP, NES, TERT
17tyrosine448.6KRT20, SYP, NES, TERT
18retinoic acid44 249.3TERT, INA, NES, SYP

GO Terms for genes affiliated with Medulloepithelioma

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Cellular components related to Medulloepithelioma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1intermediate filamentGO:0058829.5KRT20, NES

Molecular functions related to Medulloepithelioma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1structural constituent of cytoskeletonGO:0052009.1KRT20, INA

Products for genes affiliated with Medulloepithelioma

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  • Antibodies
  • Proteins
  • Lysates

Sources for Medulloepithelioma

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet