MCID: MDL003
MIFTS: 34

Medullomyoblastoma malady

Categories: Cancer diseases, Neuronal diseases

Aliases & Classifications for Medullomyoblastoma

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Aliases & Descriptions for Medullomyoblastoma:

Name: Medullomyoblastoma 10 12 65

Classifications:



External Ids:

Disease Ontology10 DOID:3861
MeSH36 D008527
SNOMED-CT59 24604009
NCIt42 C3706
UMLS65 C0205833

Summaries for Medullomyoblastoma

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MalaCards based summary: Medullomyoblastoma is related to ischemia and gastrointestinal adenoma. An important gene associated with Medullomyoblastoma is MB (Myoglobin), and among its related pathways are Notch Pathway and Spinal Cord Injury. Affiliated tissues include brain, colon and thyroid, and related mouse phenotypes are vision/eye and embryo.

Related Diseases for Medullomyoblastoma

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Diseases related to Medullomyoblastoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 174)
idRelated DiseaseScoreTop Affiliating Genes
1ischemia30.8MB, MYOG
2gastrointestinal adenoma10.5MB, SYP
3supratentorial primitive neuroectodermal tumor10.5INA, SYP
4pediculus humanus capitis infestation10.5GFAP, SYP
5adult malignant schwannoma10.5GFAP, SYP
6skin glomus tumor10.5GFAP, SYP
7anovulation10.5GFAP, SYP
8benign ependymoma10.5GFAP, SYP
9freemartinism10.5MYC, SYP
10peritoneal serous adenocarcinoma10.5SYP, TP63
11mixed glioma10.5GFAP, SYP
12familial primary hypomagnesemia with hypercalciuria and nephrocalcinosis with severe ocular involvement10.5GFAP, SYP
13bone benign neoplasm10.5MB, SYP
14focal chorioretinitis10.5MB, SYP
15pilomyxoid astrocytoma10.5GFAP, SYP
16bilateral hyperactive labyrinth10.5GFAP, SYP
17visual verbal agnosia10.5MB, SYP
18rectum kaposi's sarcoma10.5SMARCB1, SYP
19childhood cerebellar neoplasm10.5GFAP, SMARCB1
20spindle cell liposarcoma10.4MB, TP53
21sarcomatosis10.4MB, TP53
22ependymoblastoma10.4GFAP, SYP
23brain glioma10.4SYP, TP53
24thrombophlebitis10.4GFAP, SMARCB1
25external ear squamous cell carcinoma10.4MB, TP53
26anal gland neoplasm10.4SMARCB1, SYP
27alveoli adenoma10.4GFAP, TP53
28pineal gland astrocytoma10.4GFAP, TP53
29ovarian mucinous cystadenofibroma10.4GFAP, TP53
30fallopian tube serous papilloma10.4SYP, TP53
31congenital disorder of glycosylation, type if10.4GFAP, TP53
32cystic teratoma10.4SYP, TP63
33baby rattle pelvic dysplasia10.4MYC, TP53
34lateral ventricle meningioma10.4GFAP, TP53
35phagocyte bactericidal dysfunction10.4MB, MYOD1
36high molecular weight kininogen deficiency10.4TP53, TP63
37renal artery disease10.4GFAP, INA
38complement component 3 deficiency10.4GFAP, SMARCB1, SYP
39subependymal giant cell astrocytoma10.3GFAP, TP53
40papillary ependymoma10.3GFAP, SMARCB1, SYP
41eye disease10.3GFAP, TP53
42fibrosarcoma of bone10.3MYC, MYOD1
43vulval paget's disease10.3SMARCB1, TP53
44myoblastoma10.3GFAP, SAG, SYP
45behcet's syndrome arthropathy10.3GFAP, SAG, SYP
46fallopian tube teratoma10.3SYP, TP53
47sebaceous adenocarcinoma10.3GFAP, SMARCB1, TP63
48cerebellar medulloblastoma10.3GFAP, SYP, TP53
49space motion sickness10.3GFAP, SYP, TP53
50substance abuse10.3GFAP, MB, TP53

Graphical network of the top 20 diseases related to Medullomyoblastoma:



Diseases related to medullomyoblastoma

Symptoms for Medullomyoblastoma

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Drugs & Therapeutics for Medullomyoblastoma

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Medullomyoblastoma

Genetic Tests for Medullomyoblastoma

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Anatomical Context for Medullomyoblastoma

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MalaCards organs/tissues related to Medullomyoblastoma:

33
Brain, Colon, Thyroid, Ovary, Neutrophil, T cells

Animal Models for Medullomyoblastoma or affiliated genes

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MGI Mouse Phenotypes related to Medullomyoblastoma:

38 (show all 16)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053918.5GFAP, MYCN, OTX2, SAG, SMARCB1, TP53
2MP:00053808.3MB, MYC, MYCN, MYOG, OTX2, SMARCB1
3MP:00053828.2ENO2, MYC, MYCN, OTX2, TP53, TP63
4MP:00053817.9GFAP, MYC, MYCN, OTX2, PPP1R12A, SMARCB1
5MP:00053847.5ENO2, GFAP, MB, MYC, MYCN, OTX2
6MP:00028737.5GFAP, INA, MYC, MYCN, MYOD1, MYOG
7MP:00053887.4ENO2, MB, MYCN, MYOD1, MYOG, OTX2
8MP:00053867.3ENO2, GFAP, MYC, MYCN, MYOG, OTX2
9MP:00036317.2ENO2, GFAP, INA, MYC, MYCN, OTX2
10MP:00053856.9GFAP, MB, MYC, MYCN, MYOD1, OTX2
11MP:00053696.8GFAP, MB, MYC, MYCN, MYOD1, MYOG
12MP:00053766.8GFAP, MB, MYC, MYCN, MYOD1, MYOG
13MP:00107686.4GFAP, MB, MYC, MYCN, MYOD1, MYOG
14MP:00053785.5ENO2, GFAP, MB, MYC, MYCN, MYOD1

Publications for Medullomyoblastoma

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Articles related to Medullomyoblastoma:

(show all 34)
idTitleAuthorsYear
1
Anaplastic large cell lymphoma in paediatric and young adult patients. (26913827)
2016
2
Multiple glomeruloid hemangiomas without POEMS syndrome. (27126256)
2016
3
Paroxysmal cold hemoglobinuria due to an IgA donath-landsteiner antibody. (26053459)
2015
4
Tamoxifen-Induced Cell Death of Malignant Glioma Cells Is Brought About by Oxidative-Stress-Mediated Alterations in the Expression of BCL2 Family Members and Is Enhanced on miR-21 Inhibition. (26109525)
2015
5
Re. 'Left Renal Vein Division During Open Surgery of Abdominal Aortic Disease: A Propensity Score-matched Case-control Study'. (24215728)
2014
6
Utility of 14 novel biomarkers in patients with acute chest pain and undetectable levels of conventional cardiac troponin. (22507551)
2013
7
The role of impulsivity, inattention and comorbid ADHD in patients with bulimia nervosa. (23700439)
2013
8
Polymorphism of transglutaminase 2: unusually low frequency of genomic variants with deficient functions. (22160262)
2013
9
Nuclear and cytoplasmic localization of I^-catenin in the nail-matrix cells and in an onychomatricoma. (24252084)
2013
10
Elevated interferon regulatory factor 4 levels in patients with allergic asthma. (22515488)
2012
11
Leiden Open Variation Database of the MUTYH gene. (20725929)
2010
12
Cardiovascular and renal complications of type 2 diabetes in obesity: role of sympathetic nerve activity and insulin resistance. (20034369)
2010
13
Defective complex I assembly due to C20orf7 mutations as a new cause of Leigh syndrome. (19542079)
2010
14
Proteolytic and non-proteolytic roles of membrane type-1 matrix metalloproteinase in malignancy. (19406172)
2010
15
Nuclear receptors: mediators and modifiers of inflammation-induced cholestasis. (19273222)
2009
16
First report of the simultaneous occurrence of choroid plexus papilloma and meningioma in a dog. (19635711)
2009
17
Bilateral endophthalmitis in a patient with bacterial meningitis caused by Streptococcus pneumoniae. (18685258)
2008
18
Identification of a novel C-terminal cleavage of Crimean-Congo hemorrhagic fever virus PreGN that leads to generation of an NSM protein. (17409136)
2007
19
RNA-binding IMPs promote cell adhesion and invadopodia formation. (16541107)
2006
20
Evolution of duplications in the transferrin family of proteins. (15621505)
2005
21
Simultaneous bilateral occurrence of a mixed mesodermal tumor and cystadenocarcinoma in the ovary. (15188029)
2004
22
Protein expression, genomic structure, and polymorphisms of oculomedin. (12868032)
2003
23
Involvement of histone methylation and phosphorylation in regulation of transcription by thyroid hormone receptor. (12138181)
2002
24
Association of human polyomavirus JCV with colon cancer: evidence for interaction of viral T-antigen and beta-catenin. (12460931)
2002
25
The structural biology of the developing dental enamel matrix. (10441532)
1999
26
Fractionated plasma separation and adsorption system: a novel system for blood purification to remove albumin bound substances. (9950184)
1999
27
High affinity very late antigen-4 subsets expressed on T cells are mandatory for spontaneous adhesion strengthening but not for rolling on VCAM-1 in shear flow. (9916737)
1999
28
S-adenosylmethionine versus ursodeoxycholic acid in the treatment of intrahepatic cholestasis of pregnancy: preliminary results of a controlled trial. (8841797)
1996
29
Elevation of interleukin-10 levels in malignant pleural effusion. (8697847)
1996
30
The effect of UVB irradiation on proliferative activity and cell growth potential of cord blood. (8073520)
1994
31
Kinetics of transfused neutrophils in peripheral blood and BAL fluid of a patient with variant X-linked chronic granulomatous disease. (1954982)
1991
32
Two distinct receptor subtypes for mammalian bombesin-like peptides. (1726343)
1991
33
CONGENITAL hypoplastic anemia. (13452260)
1957
34
"Paradoxical" brain abscess; report of a unique case in association with Lutembacher's syndrome. (12990411)
1952

Variations for Medullomyoblastoma

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Expression for genes affiliated with Medullomyoblastoma

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Search GEO for disease gene expression data for Medullomyoblastoma.

Pathways for genes affiliated with Medullomyoblastoma

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Pathways related to Medullomyoblastoma according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.8MYC, MYCN
29.5GFAP, MYC, TP53
3
Show member pathways
9.2MYC, OTX2, TP53, TP63

GO Terms for genes affiliated with Medullomyoblastoma

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Biological processes related to Medullomyoblastoma according to GeneCards Suite gene sharing:

(show all 11)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of mesenchymal cell proliferationGO:000205310.3MYC, MYCN
2response to gamma radiationGO:001033210.1MYC, TP53
3DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediatorGO:000697810.1TP53, TP63
4intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediatorGO:004277110.0TP53, TP63
5positive regulation of muscle cell differentiationGO:005114910.0MYOD1, MYOG
6positive regulation of myoblast fusionGO:190174110.0MYOD1, MYOG
7myotube differentiationGO:001490210.0MYOD1, MYOG
8skeletal muscle fiber developmentGO:00487419.9MYOD1, MYOG
9positive regulation of transcription, DNA-templatedGO:00458938.5MYC, MYOD1, MYOG, OTX2, TP53, TP63
10regulation of transcription, DNA-templatedGO:00063557.7MYC, MYCN, MYOD1, MYOG, OTX2, TP53
11positive regulation of transcription from RNA polymerase II promoterGO:00459446.9MYC, MYCN, MYOD1, MYOG, OTX2, PPP1R12A

Molecular functions related to Medullomyoblastoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific bindingGO:00010779.4MYC, MYOG, TP63
2transcription factor activity, sequence-specific DNA bindingGO:00037008.9MYOD1, MYOG, OTX2

Sources for Medullomyoblastoma

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet