MCID: MGC001
MIFTS: 45

Megacolon malady

Category: Gastrointestinal diseases

Aliases & Classifications for Megacolon

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Aliases & Descriptions for Megacolon:

Name: Megacolon 10 12 36 65
Megacolon, Not Hirschsprung's 10 65
Megacolon Excluding Hirschsprung's Disease 10
 
Megacolon, Other Than Hirschsprung's 10
Dilatation of Colon 10
Megacolon Nos 10

Classifications:



External Ids:

Disease Ontology10 DOID:11372
ICD1027 K59.3
SNOMED-CT59 197144003
MeSH36 D008531
NCIt42 C34810
UMLS65 C0025160, C0235904

Summaries for Megacolon

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Wikipedia:68 Megacolon is an abnormal dilation of the colon (also called the large intestine). The dilation is often... more...

MalaCards based summary: Megacolon, also known as megacolon, not hirschsprung's, is related to hirschsprung disease 1 and shprintzen-goldberg syndrome. An important gene associated with Megacolon is SOX10 (SRY-Box 10), and among its related pathways are and NCAM1 interactions. Affiliated tissues include colon, breast and lung, and related mouse phenotypes are embryo and respiratory system.

Disease Ontology:10 A colonic disease that is characterized by an abnormal dilation of the colon.

Related Diseases for Megacolon

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Diseases related to Megacolon via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 415)
idRelated DiseaseScoreTop Affiliating Genes
1hirschsprung disease 132.2EDN3, EDNRB, GDNF, PHOX2B, RET
2shprintzen-goldberg syndrome31.6EDN3, EDNRB, GDNF, KIF1BP, RET
3lynch syndrome29.8EDN3, RET, SOX10
4toxic megacolon12.7
5goldberg-shprintzen megacolon syndrome12.6
6hirschsprung disease 211.6
7wagner syndrome10.5EDNRB, SOX10
8paralytic ileus10.4HTR2A, VIP
9adult brainstem gliosarcoma10.4DRD2, HTR2A
10breast osteosarcoma10.4DRD2, HTR2A
11birdshot chorioretinopathy10.4ACHE, VIP
12kluver-bucy syndrome10.4DRD2, HTR2A
13paranoid personality disorder10.3DRD2, HTR2A
14prostate adenocarcinoma10.3DRD2, HTR2A
15osmotic diarrhea10.3FOXP3, VIP
16geniculate herpes zoster10.3DRD2, HTR2A
17tarlov cysts10.3DRD2, HTR2A
18kleptomania10.3DRD2, HTR2A
19panuveitis10.3DRD2, HTR2A
20lymphoma10.3
21conjunctiva squamous cell carcinoma10.3DRD2, HTR2A
22hantavirus pulmonary syndrome10.3DRD2, HTR2A
23zebra body myopathy10.2DRD2, HTR2A, SOX10
24hirschsprung disease 610.2
25hirschsprung disease 910.2
26hirschsprung disease 310.2
27hirschsprung disease 510.2
28hirschsprung disease 810.2
29hirschsprung disease 710.2
30hirschsprung disease 410.2
31ifap syndrome with or without bresheck syndrome10.2
32autoimmune gastrointestinal dysmotility10.2
33breast cancer10.2
34prostatitis10.2
35conjunctival intraepithelial neoplasm10.2EDN3, EDNRB, SOX10
36twin-to-twin transfusion syndrome10.2EDNRB, HTR2A, VIP
37spina bifida occulta10.2EDNRB, RET
38leukemia10.2
39cervicitis10.2
40thyroiditis10.2
41endotheliitis10.2
42colorectal cancer10.1
43hepatocellular carcinoma10.1
44tuberculosis10.1
45neuronitis10.1
46chorioangioma10.1DRD2, HTR2A
47obesity10.1
48hepatitis10.1
49neuropathy10.1
50cardiomyopathy10.1

Graphical network of the top 20 diseases related to Megacolon:



Diseases related to megacolon

Symptoms for Megacolon

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Drugs & Therapeutics for Megacolon

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Drugs for Megacolon (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 18)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
VancomycinapprovedPhase 4, Phase 2, Phase 33051404-90-6441141, 14969
Synonyms:
(1S,2R,18R,22S,25R,28R,40S)-22-(2-amino-2-Oxoethyl)-48-[2-O-(3-amino-2,3,6-trideoxy-3-methyl-alpha-L-lyxo-hexopyranosyl)-beta-D-glucopyranosyloxy]-5,15-dichloro-2,18,32,35,37-pentahydroxy-19-[(N-methyl-D-leucyl)amino]-20,23,26,42,44-pentaoxo-7,13-dioxa-21,24,27,41,43-pentaazaoctacyclo[26.14.2.2(3,6).2(14,17).1(8,12).1(29,33).0(10,25).0(34,39)]pentaconta-3,5,8(48),9,11,14,16,29(45),30,32,34,36,38,46,49-pentadecaene-40-carboxylic acid
(2.2Sp,3.5sa,2.6sp)-O(4.2),C(3.4):c(5.4),O(4.6):c(3.5),C(2.7)-tricyclo[N-methyl-D-leucyl-3-chloro-(R)-beta-hydroxy-D-tyrosyl-L-asparaginyl-D-2-(4-{[2-O-(3-amino-2,3,6-trideoxy-3-C-methyl-alpha-L-lyxo-hexopyranosyl)-beta-D-glucopyranosyl]oxy}phenyl)glycyl-D-2-(4-hydroxyphenyl)glycyl-3-chloro-(R)-beta-hydroxy-L-tyrosyl-L-2-(3,5-dihydroxyphenyl)glycine]
1404-90-6
1404-93-9 (hydrochloride)
64685-75-2 (sulfate)
AC1L24VU
AC1L9AMI
AC1Q29OH
BIDD:GT0353
C06689
C66H75Cl2N9O24
CHEBI:28001
CHEMBL262777
CID14969
CID441141
CID5311496
CID6426898
CID6917992
D00212
DB00512
EINECS 215-772-6
HSDB 3262
LMPK14000004
LS-161387
 
Lopac0_001267
MolPort-001-794-649
NCGC00162383-02
Prestwick0_000497
Prestwick1_000497
Prestwick2_000497
SPBio_002314
UNII-6Q205EH1VU
VAN
VANCOMYCIN
Vancocin
Vancocin (TN)
Vancocin HCL
Vancomicina
Vancomicina [INN-Spanish]
Vancomycin
Vancomycin (USP)
Vancomycin HCL
Vancomycin Hydrochloride
Vancomycin [USAN:INN:BAN]
Vancomycine
Vancomycine [INN-French]
Vancomycinum
Vancomycinum [INN-Latin]
nchembio.350-comp1
2Anti-Infective AgentsPhase 4, Phase 2, Phase 317220
3Anti-Bacterial AgentsPhase 4, Phase 2, Phase 39140
4VaccinesPhase 46085
5
MetronidazoleapprovedPhase 2, Phase 3418443-48-14173
Synonyms:
1-(2-hydroxy-1-ethyl)-2-methyl-5-nitroimidazole
1-(2-hydroxyethyl)-2-methyl-5-nitroimidazole
1-(beta-Ethylol)-2-methyl-5-nitro-3-azapyrrole
1-(beta-Hydroxyethyl)-2-methyl-5-nitroimidazole
1-(beta-Oxyethyl)-2-methyl-5-nitroimidazole
1-(β-ethylol)-2-methyl-5-nitro-3-azapyrrole
1-(β-hydroxyethyl)-2-methyl-5-nitroimidazole
1-(β-oxyethyl)-2-methyl-5-nitroimidazole
1-Hydroxyethyl-2-methyl-5-nitroimidazole
2-(2-methyl-5-nitroimidazol-1-yl)ethanol
2-Methyl-5-nitro-1-imidazoleethanol
2-Methyl-5-nitroimidazole-1-ethanol
2-methyl-1-(2-hydroxyethyl)-5-nitroimidazole
2-methyl-3-(2-hydroxyethyl)-4-nitroimidazole
2-methyl-5-nitroimidazole-1-ethanol
443-48-1
46461_FLUKA
46461_RIEDEL
69198-10-3 (mono-hydrochloride)
99616-64-5
AB00052046
AC-10556
AC1L1HKS
AC1Q2P2Z
AKOS000269646
APMN
ARONIS24285
Acromona
Anagiardil
Apo-Metronidazole
Arilin
Atrivyl
BAS 02983617
BAY-5360
BCBcMAP01_000184
BIDD:GT0107
BPBio1_000004
BRD-K52020312-001-05-2
BRN 0611683
BSPBio_000002
BSPBio_002031
Bayer 5360
Bexon
Bio-0694
CAS-443-48-1
CB-01-14 MMX
CCRIS 410
CHEBI:39845
CHEBI:6909
CHEMBL137
CID4173
CONT
CPD000058175
Caswell No. 579AA
Clont
D00409
DB00916
Danizol
Deflamon
Deflamon-wirkstoff
DivK1c_000007
EINECS 207-136-1
EPA Pesticide Chemical Code 120401
Efloran
Elyzol
Entizol
Eumin
FLAGYL I.V. RTU IN PLASTIC CONTAINER
Flagemona
Flagesol
Flagil
Flagyl
Flagyl (TN)
Flagyl 375
Flagyl Er
Flagyl I.V.
Flagyl I.V. RTU
Flegyl
Florazole
Fossyol
Giatricol
Ginefla vir
Gineflavir
HMS1568A04
HMS1920N19
HMS2051G07
HMS2090B19
HMS2091F14
HMS500A09
HMS547C19
HSDB 3129
I14-0667
IDI1_000007
IDR-90105
KBio1_000007
KBio2_001515
KBio2_004083
KBio2_006651
KBio3_001531
KBioGR_000559
KBioSS_001515
Klion
Klont
LS-1264
M0924
M1547_SIGMA
M3761_FLUKA
M3761_SIGMA
M9036_SIGMA
METRO I.V
METRONIDAZOLE USP
MLS000028590
MLS000758286
Maybridge1_001999
Meronidal
Methronidazole
Methyl-5-nitroimidazole-1-ethanol
Metric
Metric 21
Metro Cream
Metro Gel
 
Metro I.V.
Metro I.V. In Plastic Container
MetroCream
MetroGel
MetroGel-Vaginal
MetroLotion
Metrocream
Metrodzhil
Metrogel
Metrogel-vaginal
Metrogel-vaginal (TN)
Metrogyl
Metrolag
Metrolotion
Metrolyl
Metromidol
Metronidaz
Metronidazol
Metronidazol [INN-Spanish]
Metronidazole
Metronidazole (JP15/USP/INN)
Metronidazole Benzoate
Metronidazole Monohydrochloride
Metronidazole Phosphoester
Metronidazole Topical Gel
Metronidazole [USAN:INN:BAN:JAN]
Metronidazole hydrochloride
Metronidazole in Plastic Container
Metronidazolo
Metronidazolo [DCIT]
Metronidazolum
Metronidazolum [INN-Latin]
Metrotop
Metrozine
Metryl
Mexibol
Mexibol 'silanes'
MolPort-000-141-892
MolPort-002-502-101
Monagyl
Monasin
NCGC00016446-01
NCGC00016446-02
NCGC00022059-03
NCGC00022059-04
NCGC00022059-05
NCIOpen2_000337
NIDA
NINDS_000007
NSC 50364
NSC 69587
NSC-50364
NSC50364
NSC69587
Nalox
Nidagel
Noritate
Noritate (TN)
Novonidazol
Orvagil
Prestwick0_000081
Prestwick1_000081
Prestwick2_000081
Prestwick3_000081
Prestwick_334
Protostat
RP 8823
RP-8823
Rathimed
Rosadan
Rosased
S1907_Selleck
SAM001247010
SBB041018
SC 10295
SMP1_000189
SMR000058175
SPBio_000666
SPBio_001941
SPECTRUM1500412
STK177359
Sanatrichom
Satric
Spectrum2_000883
Spectrum3_000506
Spectrum4_000060
Spectrum5_001289
Spectrum_001035
Takimetol
Trichazol
Trichex
Tricho cordes
Tricho-gynaedron
Trichocide
Trichomol
Trichomonacid 'pharmachim'
Trichopal
Trichopol
Tricocet
Tricom
Tricowas B
Trikacide
Trikamon
Trikojol
Trikozol
Trimeks
Trivazol
UNII-140QMO216E
Vagilen
Vagimid
Vandazole
Vertisal
WLN: T5N CNJ A2Q B1 ENW
WLN: T5N CNJA2Q B1 ENW
WLN: T6NTJ DQ ANU1- ET5N CNJ A1 BNW
Wagitran
ZERO/004064
ZINC00113442
Zadstat
Zidoval
giniflavir
metronidazole
neo-Tric
6Gastrointestinal AgentsPhase 2, Phase 36401
7Antibiotics, AntitubercularPhase 2, Phase 35971
8Antiprotozoal AgentsPhase 2, Phase 31730
9LaxativesPhase 2, Phase 3344
10Polyethylene glycol 3350Phase 2, Phase 390
11Antiparasitic AgentsPhase 2, Phase 31854
12CatharticsPhase 2, Phase 3344
13
Pancrelipaseapproved88053608-75-6
Synonyms:
1,4-alpha-D- glucan glucanohydrolase
Creon
PA
Pancreatic alpha-amylase precursor
Pancreaze
 
Pancrelipase
Pertzye
Polocaine-mpf
Ultresa
Viokace
Zenpep
14
Lactuloseapproved914618-18-211333
Synonyms:
(2S,3R,4S,5R,6R)-2-[(2R,3S,4S,5R)-4,5-dihydroxy-2,5-bis(hydroxymethyl)oxolan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol
4-O-b-D-Galactopyranosyl-D-Fructofuranose
4-O-b-D-Galactopyranosyl-D-fructose
4-O-beta-D-Galactopyranosyl-D-Fructofuranose
4-O-beta-D-Galactopyranosyl-D-fructofuranose
4-O-beta-D-Galactopyranosyl-D-fructose
4-O-beta-delta-Galactopyranosyl-delta-Fructofuranose
4-O-beta-delta-Galactopyranosyl-delta-fructose
Bifiteral
Cephulac
 
Constulose
D-Lactulose
Enulose
Generlac
Kristalose
Lactulosa
Lactulose
Lactulosum
delta-Lactulose
lactulosa
lactulosum
15Immunoglobulins4477
16pancreatin880
17Antibodies4477
18ColaNutraceuticalPhase 01768

Interventional clinical trials:

(show all 22)
idNameStatusNCT IDPhase
1Optimal Treatment for Recurrent Clostridium DifficileRecruitingNCT02667418Phase 4
2Probiotics for Prophylaxis of Postoperative Hirschsprungs Associated EnterocolitisRecruitingNCT02343562Phase 4
3Immunodeficiency in Cartilage-hair Hypoplasia: Sub-project on Safety of Vaccination Against ChickenpoxEnrolling by invitationNCT02383797Phase 4
4Intestinal Lavage for the Treatment of Severe C. Difficile InfectionsNot yet recruitingNCT02466698Phase 2, Phase 3
5Probiotic Prophylaxis of Hirschprung's Disease Associated Enterocolitis (HAEC)CompletedNCT00630838Phase 2
6Endoscopic Mucosal Resection for the Diagnosis of a-Ganglionosis, a Controlled Prospective Trial (EDGE Trial)RecruitingNCT01515501Phase 2
7Endoscopic Mucosal Resection (EMR) for Diagnosis of Hirschsprung's DiseaseEnrolling by invitationNCT00671684Phase 1, Phase 2
8A Trial on Conservative Treatment for Infants' Hirschsprung DiseaseCompletedNCT01985646Phase 0
9A Trial on Probiotics in Preventing Hirschsprung's Disease Associated EntercolitisCompletedNCT01934959Phase 0
10A Trial on Treatments of Hirschsprung Allied DiseaseRecruitingNCT02212054Phase 0
11Genetic Mosaicism in Hirschsprung's DiseaseRecruitingNCT01927809
12Abdominal SepsiS Study: Epidemiology of Etiology and OutcomeRecruitingNCT02442596
13Efficacy and Safety of Fecal Microbiota Transplantation for Severe Clostridium Difficile Associated ColitisRecruitingNCT01959048
14Host Immune Response to Clostridium Difficile InfectionRecruitingNCT02440438
15Enhanced Recovery After Surgery In Hirschsprung DiseaseRecruitingNCT02776176
16Fast-track Surgery in the Treatment of Hirschsprung's DiseaseRecruitingNCT02350088
173D High Resolution Anorectal Manometry in Children After Surgery for Anorectal DisordersRecruitingNCT02296008
18Comparison of Circular(Soave) and Heart-shaped Anastomosis in Hirschsprung's Disease: A Prospective Multicenter Randomized Controlled TrialRecruitingNCT02234219
19A New Scoring System Improves Diagnostic Accuracy of Intestinal Dysganglionosis --a Prospective StudyRecruitingNCT02216994
20Identification Genetic, Immunologic and Microbial Markers of Hirschsprung Associated Enterocolitis in Children With Hirschsprung DiseaseRecruitingNCT02193685
21Hirschsprung Disease Genetic StudyRecruitingNCT00478712
22Electrophysiological Activity of the Anorectum in Children Suspected of Hirschsprung DiseaseNot yet recruitingNCT02342457

Search NIH Clinical Center for Megacolon


Cochrane evidence based reviews: megacolon

Genetic Tests for Megacolon

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Anatomical Context for Megacolon

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MalaCards organs/tissues related to Megacolon:

33
Colon, Breast, Lung, Liver, Bone, Heart, Endothelial

Animal Models for Megacolon or affiliated genes

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MGI Mouse Phenotypes related to Megacolon:

38 (show all 13)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053808.3EDN3, EDNRB, GFRA1, PHOX2B, RET, SOX10
2MP:00053888.0ACHE, DRD2, EDNRB, FOXP3, PHOX2B, RET
3MP:00053677.9DRD2, EDNRB, FOXP3, GDNF, GFRA1, RET
4MP:00028737.9DRD2, FOXP3, GFRA1, PHOX2B, RET, SOX10
5MP:00053897.8ACHE, DRD2, FOXP3, GDNF, NRTN, RET
6MP:00053797.7DRD2, EDNRB, FOXP3, GDNF, HTR2A, NRTN
7MP:00053857.5DRD2, EDNRB, FOXP3, GDNF, KIF1BP, PHOX2B
8MP:00053697.1ACHE, DRD2, EDNRB, GDNF, GFRA1, HTR2A
9MP:00053847.0DRD2, EDNRB, FOXP3, GDNF, GFRA1, PHOX2B
10MP:00053816.7DRD2, EDN3, EDNRB, FOXP3, GDNF, GFRA1
11MP:00036316.6ACHE, DRD2, EDN3, EDNRB, GDNF, GFRA1
12MP:00053865.7ACHE, DRD2, EDN3, EDNRB, FOXP3, GDNF
13MP:00107685.0ACHE, DRD2, EDN3, EDNRB, FOXP3, GDNF

Publications for Megacolon

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Articles related to Megacolon:

(show top 50)    (show all 554)
idTitleAuthorsYear
1
The Effects of Cigarette Smoke Condensate and Nicotine on Periodontal Tissue in a Periodontitis Model Mouse. (27203240)
2016
2
Targeting glutamate to treat schizophrenia: lessons from recent clinical studies. (27212398)
2016
3
New approaches in primary central nervous system lymphoma. (25841718)
2015
4
Role of cytokine gene polymorphisms on prognosis in hepatocellular carcinoma after radical surgery resection. (24768182)
2014
5
Acute renal failure and severe thrombocytopenia associated with metamizole. (24434395)
2014
6
Seroprevalence of rubella among pregnant women in Khartoum state, Sudan. (24313044)
2013
7
Phaeochromocytoma masquerading as anxiety and depression. (23826457)
2013
8
Pulmonary metastasis from encapsulated cervical ectopic type a thymoma. (23176955)
2012
9
Cross validation with the mood disorder questionnaire (MDQ) of an instrument for the detection of hypomania in Brazil: The 32 item hypomania symptom check-list, first Revision (HCI-32-R1). (22284020)
2012
10
Alcohol and cannabis abuse/dependence symptoms and life satisfaction in young adulthood. (21733007)
2012
11
Cholesterol and cognitive performance in normal controls and the influence of elective statin use after conversion to mild cognitive impairment: results in a clinical trial cohort. (20224282)
2010
12
Non-selective cation channel-mediated Ca2+-entry and activation of Ca2+/calmodulin-dependent kinase II contribute to G2/M cell cycle arrest and survival of irradiated leukemia cells. (21063097)
2010
13
Lack of association between peroxisome proliferator-activated receptors alpha and gamma2 polymorphisms and progressive liver damage in patients with non-alcoholic fatty liver disease: a case control study. (20825652)
2010
14
Postmenopausal estrogen monotherapy-associated breast cancer risk is modified by CYP17A1_-34_T>C polymorphism. (19672705)
2010
15
Transforming growth factor-beta1 gene C-509T and T869C polymorphisms as possible risk factors in rheumatic heart disease in Egypt. (20458825)
2010
16
Upper airway considerations in hereditary angioedema. (19949324)
2010
17
Surgical interventions for malignant middle cerebral infarction--saving lives and functionality or increasing disabled survivors? (20527622)
2010
18
Hepatitis B virus X protein suppresses adriamycin-induced apoptosis of hepatocellular carcinoma cells and expression of p53 and PTEN]. (20813662)
2010
19
Bilateral anterior uveitis after intense pulsed light therapy for pigmented eyelid lesions. (18554285)
2008
20
Snail and Slug promote epithelial-mesenchymal transition through beta-catenin-T-cell factor-4-dependent expression of transforming growth factor-beta3. (18799618)
2008
21
Spectrum of HLXB9 gene mutations in Currarino syndrome and genotype-phenotype correlation. (18449898)
2008
22
Effect of botulinum toxin A-induced paralysis and exercise training on mechanosensing and signalling gene expression in juvenile rat gastrocnemius muscle. (18603602)
2008
23
Eliminating complement factor D reduces photoreceptor susceptibility to light-induced damage. (17962484)
2007
24
Public-private partnership works to stamp out sleeping sickness in Uganda. (17392023)
2007
25
cDNA cloning and phylogenetic analysis of the sixth complement component in rainbow trout. (16271768)
2006
26
Botulinum toxin therapy for cervical dystonia. (16785112)
2006
27
Identification by phage display of single-domain antibody fragments specific for the ODD domain in hypoxia-inducible factor 1alpha. (16482104)
2006
28
Rheumatoid factor is a marker of disease severity in Korean rheumatoid arthritis. (16127769)
2005
29
Juvenile hyaline fibromatosis. (15235211)
2004
30
Coexpression of hepatocyte growth factor and its receptor c-Met correlates with high MIB-1 proliferative index in malignant fibrous histiocytoma. (15239348)
2004
31
Outbreak of campylobacteriosis at a senior center. (11300242)
2001
32
Nerve growth factor expression and release in allergic inflammatory disease of the upper airways. (10806167)
2000
33
George Leith Roupell FRS (1797-1854): significant contributions to the early nineteenth-century understanding of cholera and typhus. (10994040)
2000
34
Disruption of microtubules in living cells by tyrphostin AG-1714. (10706777)
2000
35
A response element for the homeodomain transcription factor Ptx3 in the tyrosine hydroxylase gene promoter. (10800925)
2000
36
Genetic polymorphism of cytochrome P450s, CYP2C19, and CYP2C9 in a Japanese population. (9631918)
1998
37
A lymphokine-activated killer (LAK)-resistant cell line, and low expression of adhesion molecules LFA-3 and VCAM-1 on its cell surface. (9802061)
1998
38
Genetic susceptibility to the development of autoimmune disease. (9497784)
1997
39
Early increase of TNF alpha and IL-6 in tracheobronchial aspirate fluid indicator of subsequent chronic lung disease in preterm infants. (9462189)
1997
40
Relation between treatment efficacy and cumulative dose of alpha interferon in chronic hepatitis B. European Concerted Action on Viral Hepatitis (Eurohep). (9007705)
1996
41
Coagulopathy due to an acquired factor V inhibitor and subsequently thrombosis. (7741151)
1995
42
Direct activation of the phosphatidylinositol 3'-kinase by the insulin receptor. (8276809)
1994
43
Thyroxine-binding globulin variant (TBG-Kumamoto): identification of a point mutation and genotype analysis of its family. (1294376)
1992
44
Heterozygous alpha 1-antichymotrypsin deficiency may be associated with cold urticaria. (1485647)
1992
45
Inhibition of thrombin generation by heparin and low molecular weight (LMW) heparins in the absence and presence of platelet factor 4 (PF4). (1329921)
1992
46
Calciphylaxis in a renal dialysis patient with secondary hyperparathyroidism. (3452312)
1987
47
Isolation of the insoluble straight fibrils of Pick's disease. (3681329)
1987
48
Anatomic variations in underdeveloped right ventricle related to tricuspid atresia and stenosis. (957756)
1976
49
Miliary tuberculosis of the lung in Nigerian adults. (1164907)
1975
50

Variations for Megacolon

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Expression for genes affiliated with Megacolon

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Search GEO for disease gene expression data for Megacolon.

Pathways for genes affiliated with Megacolon

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GO Terms for genes affiliated with Megacolon

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Biological processes related to Megacolon according to GeneCards Suite gene sharing:

(show all 20)
idNameGO IDScoreTop Affiliating Genes
1posterior midgut developmentGO:000749710.7EDNRB, RET
2vein smooth muscle contractionGO:001482610.7EDN3, EDNRB
3enteric nervous system developmentGO:004848410.6EDNRB, PHOX2B
4vasoconstrictionGO:004231010.5EDN3, EDNRB
5peripheral nervous system developmentGO:000742210.5EDNRB, GDNF
6regulation of sensory perception of painGO:005193010.4EDNRB, VIP
7positive regulation of penile erectionGO:006040610.3EDNRB, VIP
8positive regulation of renal sodium excretionGO:003581510.3DRD2, EDNRB
9pigmentationGO:004347310.3DRD2, EDNRB
10artery smooth muscle contractionGO:001482410.2EDN3, HTR2A
11neuron differentiationGO:00301829.9EDN3, PHOX2B, RET
12peristalsisGO:00304329.9DRD2, GDNF
13positive regulation of neuroblast proliferationGO:00020529.8DRD2, SOX10
14MAPK cascadeGO:00001659.8GDNF, NRTN, RET
15neural crest cell migrationGO:00017559.7EDN3, EDNRB, RET, ZEB2
16behavioral response to cocaineGO:00481489.5DRD2, HTR2A
17temperature homeostasisGO:00016599.4DRD2, HTR2A
18regulation of dopamine uptake involved in synaptic transmissionGO:00515849.4DRD2, GDNF
19nervous system developmentGO:00073999.4ACHE, EDNRB, GDNF, NRTN
20positive regulation of transcription from RNA polymerase II promoterGO:00459448.6DRD2, FOXP3, GDNF, SOX10, ZEB2

Molecular functions related to Megacolon according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1Ras guanyl-nucleotide exchange factor activityGO:00050889.1GFRA1, NRTN, RET

Sources for Megacolon

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
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29ICD9CM
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31KEGG
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38MGI
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50OMIM via Orphanet
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66UMLS via Orphanet