MCID: MLN009
MIFTS: 20

Melanotic Neurilemmoma malady

Category: Cancer diseases

Aliases & Classifications for Melanotic Neurilemmoma

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Aliases & Descriptions for Melanotic Neurilemmoma:

Name: Melanotic Neurilemmoma 11 13 68
Pigmented Neurilemmoma 11
 
Melanotic Schwannoma 11
Pigmented Schwannoma 11

Classifications:



External Ids:

Disease Ontology11 DOID:3205
NCIt45 C6970

Summaries for Melanotic Neurilemmoma

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MalaCards based summary: Melanotic Neurilemmoma, also known as pigmented neurilemmoma, is related to carney complex, type 1 and carney complex variant. An important gene associated with Melanotic Neurilemmoma is PMEL (Premelanosome Protein). Related mouse phenotypes are pigmentation and neoplasm.

Related Diseases for Melanotic Neurilemmoma

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Diseases related to Melanotic Neurilemmoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 91)
idRelated DiseaseScoreTop Affiliating Genes
1carney complex, type 111.2
2carney complex variant11.1
3verrucous papilloma10.3PMEL, TYR
4craniosynostosis 610.2PMEL, TYR
5cavernous sinus meningioma10.2LYZ, PMEL
6mediastinitis10.2MLANA, PMEL
7intracranial embolism10.2MLANA, TYR
8external ear basal cell carcinoma10.2MLANA, TYR
9primary familial brain calcification10.2NF2, PTEN
10anorexia nervosa 110.2NF2, PTEN
11vulval paget's disease10.2MLANA, TYR
12aneurysm of sinus of valsalva10.2NF2, PTEN
13vaginal yolk sac tumor10.1MLANA, TYR
14cavernous hemangioma of colon10.1CD34, NF2
15intraneural perineurioma10.1CD34, TYR
16spinal meninges cancer10.1CD34, NF2
17parotid gland adenoid cystic carcinoma10.1MLANA, PTEN
18mucoepidermoid esophageal carcinoma10.1CD34, TYR
19retroperitoneal leiomyosarcoma10.1MLANA, TYR
20jejunal somatostatinoma10.1CD34, NF2
21monckeberg arteriosclerosis10.1CD34, NF2
22epidural abscess10.1NF2, PTEN
23anterior corneal pigmentation10.1PMEL, TYR
24dermoid cyst10.1CD34, PTEN
25c-p angle neurinoma10.1NF2, TYR
26vascular myelopathy10.1CD34, NF2
27renal adenoma10.1CD34, LYZ
28lattice corneal dystrophy10.1PMEL, TYR
29hodgkin's lymphoma, lymphocytic depletion10.1CD34, PTEN
30hashimoto's encephalitis10.1MLANA, PMEL, TYR
31portal vein thrombosis10.1MLANA, PMEL, TYR
32intestinal benign neoplasm10.1NF2, PTEN
33nail disorder, nonsyndromic congenital, 710.1MLANA, PMEL, TYR
34hormone producing pituitary cancer10.1CD34, MLANA
35pharynx cancer10.1CD34, NF2
36pediatric germ cell cancer10.1MLANA, PMEL, TYR
37pineal dysgerminoma10.1NF2, PTEN
38pathologic nystagmus10.0CD34, NF2
39chiasmal syndrome10.0CD68, LYZ
40hemangioma of liver10.0CD68, LYZ
41liver rhabdomyosarcoma10.0CD68, LYZ
42pigmented villonodular synovitis10.0CD68, LYZ
43mammary paget's disease10.0CD68, LYZ
44skin amelanotic melanoma10.0CD68, MLANA
45teeth hard tissue disease10.0CD68, MLANA
46endodermal sinus tumor10.0CD68, LYZ
47alpha chain disease10.0MLANA, TYR
48rosacea conjunctivitis10.0CD68, LYZ
49progressive external ophthalmoplegia with mitochondrial dna deletions, autosomal dominant 310.0MLANA, PTEN, TYR
50bulbar polio10.0CD68, LYZ

Graphical network of the top 20 diseases related to Melanotic Neurilemmoma:



Diseases related to melanotic neurilemmoma

Symptoms & Phenotypes for Melanotic Neurilemmoma

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MGI Mouse Phenotypes related to Melanotic Neurilemmoma according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00011869.5MLANA, PMEL, PTEN, TYR
2MP:00020068.9CD34, LYZ, NF2, PTEN, TYR
3MP:00030128.7CD68, LYZ, MLANA, PMEL, TYR
4MP:00053878.1CD34, CD68, LYZ, NF2, PTEN, TYR
5MP:00107718.0CD34, LYZ, MLANA, NF2, PMEL, PTEN
6MP:00053907.9CD68, LYZ, NF2, PTEN, TYR

Drugs & Therapeutics for Melanotic Neurilemmoma

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Melanotic Neurilemmoma

Genetic Tests for Melanotic Neurilemmoma

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Anatomical Context for Melanotic Neurilemmoma

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Publications for Melanotic Neurilemmoma

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Variations for Melanotic Neurilemmoma

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Expression for genes affiliated with Melanotic Neurilemmoma

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Search GEO for disease gene expression data for Melanotic Neurilemmoma.

Pathways for genes affiliated with Melanotic Neurilemmoma

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GO Terms for genes affiliated with Melanotic Neurilemmoma

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Cellular components related to Melanotic Neurilemmoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1melanosomeGO:00424709.2MLANA, PMEL, TYR

Biological processes related to Melanotic Neurilemmoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1melanin biosynthetic processGO:004243810.2PMEL, TYR
2regulation of protein stabilityGO:00316479.5NF2, PTEN
3cell proliferationGO:00082839.5CD34, PTEN, TYR

Sources for Melanotic Neurilemmoma

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet