MCID: MLD001
MIFTS: 60

Melioidosis malady

Infectious, Immune categories

Summaries for Melioidosis

Sources:
8Disease Ontology, 3CDC, 64Wikipedia, 33MalaCards
See all sources

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Disease Ontology:8 A primary bacterial infectious disease that results in infection, has material basis in burkholderia pseudomallei, which is transmitted by contact with the contaminated water or soil. the infection has symptom fever, has symptom respiratory distress, has symptom chest pain, and has symptom stomach pain.

MalaCards: Melioidosis, also known as acute and fulminating melioidosis, is related to sepsis and tuberculosis, and has symptoms including fever, chest pain and respiratory distress. An important gene associated with Melioidosis is TLR4 (toll-like receptor 4), and among its related pathways are MIF Action Through Endocytic Pathway and MSP-RON Signaling. The compounds gm-csf and cycloheximide have been mentioned in the context of this disorder. Affiliated tissues include skin, liver and spinal cord, and related mouse phenotypes are tumorigenesis and liver/biliary system.

CDC:3 Melioidosis, also called Whitmore's disease, is an infectious disease that can infect humans or animals. The disease is caused by the bacterium Burkholderia pseudomallei.

Wikipedia:64 Melioidosis is an infectious disease caused by a Gram-negative bacterium, Burkholderia pseudomallei,... more...

Aliases & Classifications for Melioidosis

Sources:
8Disease Ontology, 10DISEASES, 45Novoseek, 49Orphanet, 61UMLS, 57SNOMED-CT, 27ICD9CM, 35MeSH, 26ICD10 via Orphanet, 58SNOMED-CT via Orphanet, 62UMLS via Orphanet, 36MESH via Orphanet, 25ICD10
See all sources

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Infectious
Anatomical: Immune


Characteristics (Orphanet epidemiological data):

49
melioidosis:
Age of onset: Variable


Aliases & Descriptions:

melioidosis 8 10 45 49 61
acute and fulminating melioidosis 8
subacute and chronic melioidosis 8
nightcliff gardener's disease 8
melioidosis, unspecified 8
epizootic lymphangitis 61
whitmore's disease 8
pseudoglanders 8


External Ids:

Disease Ontology8 DOID:5052
ICD9CM27 025
MeSH35 D008554
ICD10 via Orphanet26 A24.1, A24.2, A24.3 A24.4, more
SNOMED-CT via Orphanet58 428111003
UMLS via Orphanet62 C0025229
MESH via Orphanet36 D008554

Related Diseases for Melioidosis

Sources:
17GeneCards, 18GeneDecks
See all sources

Diseases related to Melioidosis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 161)
idRelated DiseaseScoreTop Affiliating Genes
1sepsis30.7TLR4, TLR2, TLR5, TLR1, CSF3, IRAK3
2tuberculosis30.4TLR4, TLR2, TLR1, TREM1, MIF, CXCR3
3arthritis30.3TLR4, TLR2, MIF, CXCR3, CXCL9, IL15
4septic shock30.2TLR4, TLR2, CSF3, F5, TREM1, MIF
5cystic fibrosis30.1TLR4
6pulmonary tuberculosis30.0IL18, IL10, TLR2
7bronchiolitis29.8TLR4
8bronchiolitis obliterans29.8CXCR3
9systemic lupus erythematosus29.8TLR4, TLR2, TLR5, MIF, CXCR3, IL15
10lymphangitis10.9
11glanders10.5
12splenic abscess10.3
13leptospirosis10.2
14septic arthritis10.2
15melioidosis, susceptibilty to10.2
16cellulitis10.1
17necrotizing fasciitis10.1
18orbital cellulitis10.1
19n syndrome10.1
20aortic aneurysm10.1
21leprosy10.0TLR2
22meningitis10.0TLR2
23measles10.0TLR2
24otitis media10.0TLR2
25herpes simplex10.0TLR2
26viral hepatitis10.0TLR2
27acute myocardial infarction10.0MIF
28pulmonary fibrosis10.0CXCR3
29skin disease10.0CXCL9
30visceral leishmaniasis10.0FAM120B
31aspergillosis10.0TLR2, TLR4
32graves' disease10.0CXCR3
33encephalitis10.0CXCL9, TLR2
34multiple myeloma10.0CSF3
35adenocarcinoma10.0PLAUR
36infertility10.0MIF
37filariasis10.0TLR2, TLR4
38celiac disease10.0IL15
39sjogren's syndrome10.0CXCR3, CXCL9
40chorioamnionitis10.0TLR2, TLR4
41lung cancer10.0CSF3
42lichen planus10.0CXCL9, CXCR3
43myocardial infarction10.0F5
44pemphigus10.0PLAUR
45hepatitis10.0IL18, TLR2
46invasive aspergillosis10.0TLR2, TLR4
47glomerulonephritis10.0CXCL9, MIF
48coronary heart disease10.0IL18, TLR4
49neutropenia10.0CSF3
50leishmaniasis10.0IL10

Graphical network of the top 20 diseases related to Melioidosis:



Diseases related to melioidosis

Clinical Features for Melioidosis

Sources:
8Disease Ontology
See all sources


Symptoms:

8 (see all 4)
  • fever
  • chest pain
  • respiratory distress
  • stomach pain

Drugs & Therapeutics for Melioidosis

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials, 61UMLS, 41NDF-RT
See all sources

Approved drugs:

Search CenterWatch for Melioidosis

Drug clinical trials:

Search ClinicalTrials for Melioidosis

Search NIH Clinical Center for Melioidosis

Search CenterWatch for Melioidosis

Genetic Tests for Melioidosis

Anatomical Context for Melioidosis

Sources:
33MalaCards
See all sources

MalaCards organs/tissues related to Melioidosis:

33
Skin, Liver, Spinal cord, Brain, Kidney, Lung, Spleen, Whole blood, Breast, Prostate, Myeloid, Monocytes, T cells, B cells, Endothelial

Animal Models for Melioidosis or affiliated genes

Sources:
37MGI, 28inGenious Targeting Laboratory
See all sources

Publications for Melioidosis

Sources:
51PubMed
See all sources

Articles related to Melioidosis:

(show top 50)    (show all 508)
idTitleAuthorsYear
1
The Role of NOD2 in Murine and Human Melioidosis. (24298015)
2014
2
Common TLR1 Genetic Variation Is Not Associated with Death from Melioidosis, a Common Cause of Sepsis in Rural Thailand. (24392083)
2014
3
Melioidosis as a consequence of sporting activity. (23732257)
2013
4
Activities of daily living associated with acquisition of melioidosis in northeast Thailand: a matched case-control study. (23437412)
2013
5
Potential of recombinant flagellin fragment from Burkholderia thailandensis as an antigen for melioidosis antibody detection by indirect ELISA. (23159530)
2013
6
Improved diagnosis of melioidosis using a 2-dimensional immunoarray. (24041552)
2013
7
Glyburide reduces bacterial dissemination in a mouse model of melioidosis. (24147174)
2013
8
Prevalence of melioidosis in patients with suspected pulmonary tuberculosis and sputum smear negative for acid-fast bacilli in northeast Thailand. (24062474)
2013
9
Cerebral melioidosis for the first time in the western hemisphere. (23767895)
2013
10
Trimethoprim-sulfamethoxazole versus trimethoprim-sulfamethoxazole plus doxycycline as oral eradicative treatment for melioidosis (MERTH): a multicentre, double-blind, non-inferiority, randomised controlled trial. (24284287)
2013
11
Reply re: "ocular melioidosis". (24022359)
2013
12
Overexpression of the endothelial protein C receptor is detrimental during pneumonia-derived gram-negative sepsis (Melioidosis). (23875041)
2013
13
Osteomyelitis and septic arthritis from infection with Burkholderia pseudomallei: A 20-year prospective melioidosis study from northern Australia. (24403756)
2013
14
Melioidosis breast abscesses. (22285589)
2012
15
Disseminated melioidosis presenting as septic arthritis. (23409422)
2012
16
Particle-size dependent effects in the Balb/c murine model of inhalational melioidosis. (22919690)
2012
17
Neurologic melioidosis in a child: unique clinical features and challenges of serologic diagnosis. (22760535)
2012
18
Incidence of bacteremic melioidosis in eastern and northeastern Thailand. (21734135)
2011
19
Combining vaccination and postexposure CpG therapy provides optimal protection against lethal sepsis in a biodefense model of human melioidosis. (21791666)
2011
20
Present and future therapeutic strategies for melioidosis and glanders. (20192686)
2010
21
Clinical characteristics and outcomes of bacteraemic melioidosis in a teaching hospital in a northeastern state of Malaysia: a five-year review. (20818090)
2010
22
Evaluation of IgM ELISA using a sonicate and a lipopolysaccharide antigen for the serodiagnosis of melioidosis. (20404465)
2010
23
Genomic transcriptional profiling identifies a candidate blood biomarker signature for the diagnosis of septicemic melioidosis. (19903332)
2009
24
In vitro interactions between cotrimoxazole and doxycycline in Burkholderia pseudomallei: how important is this combination in maintenance therapy of melioidosis? (19172079)
2009
25
A mimicry of melioidosis by Klebsiella ozaenae infection. (20514860)
2009
26
Landscape changes influence the occurrence of the melioidosis bacterium Burkholderia pseudomallei in soil in northern Australia. (19156200)
2009
27
Melioidosis after brief exposure: a serologic survey in US Marines. (19190209)
2009
28
Burkholderia pseudomallei isocitrate lyase is a persistence factor in pulmonary melioidosis: implications for the development of isocitrate lyase inhibitors as novel antimicrobials. (19620343)
2009
29
Protective efficacy of heat-inactivated B. thailandensis, B. mallei or B. pseudomallei against experimental melioidosis and glanders. (19490962)
2009
30
Proceedings from the 5th World Melioidosis Congress. Khon Kaen, Thailand. November 21-23, 2007. (19787859)
2008
31
Melioidosis: an uncommon cause of neck abscess. (18061838)
2008
32
The global distribution of Burkholderia pseudomallei and melioidosis: an update. (19121666)
2008
33
Melioidosis of the parotid: the tip of the iceberg. (18984274)
2008
34
Expression profile and function of triggering receptor expressed on myeloid cells-1 during melioidosis. (18008257)
2007
35
Imported melioidosis with an isolated cutaneous presentation in a 90-year-old traveller from Bangladesh. (17402688)
2007
36
Lymphocytic pleural effusion in acute melioidosis. (17964969)
2007
37
Simultaneous infection with more than one strain of Burkholderia pseudomallei is uncommon in human melioidosis. (17804651)
2007
38
Melioidosis in an Italian tourist injured by the tsunami in Thailand. (17024805)
2006
39
Melioidosis in the Americas. (17123994)
2006
40
Melioidosis: an imported case from Madagascar. (16987131)
2006
41
Cutaneous melioidosis in a Swedish tourist after the tsunami in 2004. (16338844)
2006
42
Melioidosis and the vascular surgeon: Hospital Kuala Lumpur experience. (16234087)
2005
43
Rapid serological diagnosis of melioidosis: an evaluation of a prototype immunochromatographic test. (16028848)
2005
44
A proposed scoring system for predicting mortality in melioidosis. (15307431)
2003
45
Melioidosis vaccines. (12901586)
2002
46
Case report: recovery from persistent septicemic melioidosis. (11504412)
2001
47
Distribution of immunoglobulin classes and IgG subclasses against a culture filtrate antigen of Burkholderia pseudomallei in melioidosis patients. (11192506)
2001
48
Transient asceptic arthritis of knees in a patient with melioidosis. (11214516)
2000
49
Comparison of the polymerase chain reaction and serologic tests for diagnosis of septicemic melioidosis. (11388506)
2000
50
Melioidosis and its Relation to Glanders. (20474845)
1925

Genetic Variations for Melioidosis

Expression for genes affiliated with Melioidosis

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Melioidosis

Search GEO for disease gene expression data for Melioidosis.

Pathways for genes affiliated with Melioidosis

Sources:
52QIAGEN, 30KEGG, 12EMD Millipore, 4Cell Signaling Technology, 54Reactome, 53R&D Systems, 60Tocris Bioscience, 56SinoBiological, 38NCBI BioSystems Database
See all sources

Pathways related to Melioidosis according to GeneCards/GeneDecks:

(show all 33)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
110.1MIF, TLR4
29.9IL18, TLR2, TLR4
39.9TLR4, TLR5, IL18
4
Hide members
9.9TLR4, IRAK3, MIF
59.9IL10, TLR2, TLR4
6
Immune response Bacterial infections in normal airways
9.8TLR4, TLR2, TLR5, TLR1
79.8IRAK3, TLR1, TLR2, TLR4
89.7IL18, TLR5, TLR2, TLR4
99.6TLR1, TLR10, TLR5, TLR2, TLR4
10
Hide members
9.6TLR4, TLR2, TLR5, TLR10, TLR1
119.6TLR4, TLR2, TLR5, TLR10, TLR1
12
Hide members
9.6TLR4, TLR2, TLR5, TLR10, TLR1
139.6TLR4, TLR2, TLR5, TLR10, TLR1
14
Hide members
9.6TLR4, TLR2, TLR5, TLR10, TLR1
159.6TLR4, TLR2, TLR5, TLR1, IRAK3
169.6IL18, IL10, IL15
17
Hide members
9.5IL18, IL15, TLR2, TLR4
189.5TLR4, TLR2, IL15, IL18
199.5TLR4, TLR2, TLR1, IL10, IL18
20
Hide members
9.5IL18, IL10, TLR5, TLR2, TLR4
21
Hide members
9.5IRAK3, CXCR3, IL15, IL18
22
Hide members
9.4TLR4, TLR2, TLR5, TLR10, TLR1, IRAK3
23
Hide members
9.4TLR4, TLR2, TLR5, TLR10, TLR1, IRAK3
24
Hide members
9.4TLR4, TLR2, TLR5, TLR10, TLR1, IL18
259.3CSF3, IL15, IL10
26
Hide members
9.2TLR4, TLR2, TLR5, TLR1, CXCL9, IL10
279.2TLR4, TLR2, CSF3, IL10, IL18
28
Hide members
9.1IL15, CXCL9, CXCR3, CSF3
29
Hide members
9.1TLR4, TLR2, TLR5, TLR10, TLR1, IL10
30
Hide members
9.1TLR4, TLR2, TLR5, TLR10, TLR1, IRAK3
31
Hide members
9.1TLR4, TLR2, TLR5, TLR10, TLR1, TREM1
32
Hide members
9.0TLR4, CSF3, CXCR3, CXCL9, IL15
33
Hide members
7.6IL18, TLR4, TLR2, TLR5, TLR10, TLR1

Compounds for genes affiliated with Melioidosis

Sources:
45Novoseek, 29IUPHAR, 60Tocris Bioscience, 11DrugBank, 50PharmGKB, 24HMDB, 2BitterDB
See all sources

Compounds related to Melioidosis according to GeneCards/GeneDecks:

(show top 50)    (show all 93)
idCompoundScoreTop Affiliating Genes
1gm-csf45 2911.6IL10
2cycloheximide4510.4IL18, TLR2
3pam2csk46010.4TLR4, TLR2, TLR1
4pam3csk46010.4TLR4, TLR2, TLR1
5poly(i:c)6010.3TLR4, TLR1, TLR2
6loxoribine45 2911.3TLR5, TLR2, TLR4
7resiquimod45 6011.3TLR4, TLR2, TLR1
8glucuronoxylomannan4510.2IL10, TLR2, TLR4
9dextran sulfate sodium4510.2TLR4, MIF, IL18
10imiquimod45 29 60 1112.9TLR4, TLR2, TLR1, IL10, IL18
11groalpha459.9CXCR3, CXCL9, IL10, IL18
12creatinine459.9F5, CXCR3, CXCL9, PLAUR
13flagellin45 2910.8TLR4, TLR2, TLR5, TLR1, CXCR3, IL18
14allergens459.8TLR4, CXCR3, IL10, IL18
15tuberculin459.8IL18, IL10, IL15, MIF
16tarc459.8CXCR3, CXCL9, IL10, IL18
17ifn-alpha459.8TLR4, CXCR3, CXCL9, IL10, IL18
18poly(i-c)459.7TLR4, TLR2, TLR5, IL15, IL18
19lipoteichoic acid459.7TLR4, TLR2, TLR5, TLR1, IL10, IL18
20etanercept45 50 1111.7IL18, IL10, IL15, CXCR3
21simvastatin45 50 60 29 11 2414.7TLR4, TLR2, F5, IL10, IL18
22polyinosinic-polycytidylic acid459.7TLR4, TLR2, IL15, IL10, IL18
23dexamethasone45 50 29 1112.6TLR4, TLR2, CXCL9, IL15, PLAUR
24infliximab45 50 1111.6TLR4, CXCR3, IL15, IL10, IL18
25ccl445 2910.6TLR2, CXCR3, CXCL9, IL15
26endotoxin459.6PLAUR, CSF3, IRAK3, F5, CXCR3
27mycophenolate mofetil45 50 1111.6IL18, IL10, F5, CSF3
28ribavirin45 50 1111.6CSF3, CXCR3, IL10, IL18
29anti-fungal459.6IL15, CSF3, TLR2, TLR4
30sb 20358045 6010.6PLAUR, IL18, IL10, MIF, TLR2, TLR4
31peptidoglycan45 2910.5TLR4, TLR2, TLR5, TLR1, IL15, IL10
32superoxide45 2410.5CSF3, CXCR3, IL15
33tgf beta1459.5TLR4, IL15, IL10, IL18, PLAUR
34chloroquine45 2 50 29 1113.4IL18, IL10, IL15, TLR4
35ionomycin459.4IL18, IL10, IL15, CXCL9, TLR2
36rantes459.3TLR4, TLR2, TLR5, CSF3, CXCR3, IL15
37cyclophosphamide45 50 1111.3CSF3, F5, MIF, CXCL9, IL15
38il-12459.3IL18, IL10, IL15
39tacrolimus45 50 1111.2TLR4, TLR2, F5, CXCR3, IL15, IL10
40il 10459.2TLR4, TLR2, CXCR3, CXCL9, IL15, IL10
41histamine45 29 2411.2TLR4, TLR2, CXCR3, CXCL9, IL15, IL10
42cyclosporin a45 29 6010.9IL18, IL10, IL15, CSF3, TLR2, TLR4
43thymidine45 249.8CSF3, MIF, CXCR3, IL15, IL10, IL18
44alanine458.8TLR2, F5, MIF, IL15, IL18, PLAUR
45ccl345 299.8TLR4, TLR2, CSF3, CXCR3, CXCL9, IL15
46phosphatidylinositol458.7TLR4, TLR2, TLR5, CXCR3, CXCL9, IL15
47retinoic acid45 249.5TLR4, TLR2, CSF3, F5, MIF, IL15
48nitric oxide45 11 2410.5TLR4, TLR2, F5, MIF, CXCR3, CXCL9
49vegf458.0TLR4, TLR2, CSF3, F5, MIF, CXCR3
50tyrosine458.0TLR4, TLR2, TLR5, CSF3, TREM1, MIF

GO Terms for genes affiliated with Melioidosis

Sources:
16Gene Ontology
See all sources

Cellular components related to Melioidosis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1Toll-like receptor 1-Toll-like receptor 2 protein complexGO:03535410.2TLR1, TLR2
2external side of plasma membraneGO:0098979.7TLR4, TLR2, CXCR3, CXCL9
3integral to plasma membraneGO:0058879.1PLAUR, IL15, CXCR3, TLR1, TLR2, TLR4
4extracellular spaceGO:0056158.5IL18, CSF3, F5, MIF, CXCL9, IL15
5extracellular regionGO:0055768.2F5, TREM1, MIF, CXCL9, IL15, IL18
6plasma membraneGO:0058868.2TLR4, TLR2, TLR5, TLR10, TLR1, F5

Biological processes related to Melioidosis according to GeneCards/GeneDecks:

(show all 38)
idNameGO IDScoreTop Affiliating Genes
1cellular response to triacyl bacterial lipopeptideGO:07172710.5TLR2, TLR1
2detection of triacyl bacterial lipopeptideGO:04249510.5TLR2, TLR1
3detection of diacyl bacterial lipopeptideGO:04249610.5TLR1, TLR2
4positive regulation of macrophage cytokine productionGO:06090710.4TLR4, TLR2
5positive regulation of toll-like receptor signaling pathwayGO:03412310.4TLR2, TLR5
6cellular response to lipoteichoic acidGO:07122310.4TLR2, TLR4
7positive regulation of tumor necrosis factor biosynthetic processGO:04253510.4TLR4, TLR2, TLR1
8regulation of cytokine secretionGO:05070710.4TLR1, TLR10, TLR4
9negative regulation of interleukin-17 productionGO:03270010.3TLR2, TLR4
10positive regulation of chemokine productionGO:03272210.3TLR4, TLR2, IL18
11T-helper 1 type immune responseGO:04208810.3IL18, TLR1, TLR4
12positive regulation of NF-kappaB import into nucleusGO:04234610.3IL18, TLR2, TLR4
13type 2 immune responseGO:04209210.3IL18, IL10
14positive regulation of MHC class II biosynthetic processGO:04534810.3IL10, TLR4
15macrophage activationGO:04211610.3TLR1, TLR4
16lipopolysaccharide-mediated signaling pathwayGO:03166310.3TLR4, TLR2, IL18
17positive regulation of tumor necrosis factor productionGO:03276010.3TLR4, TLR2, IL18
18negative regulation of interleukin-12 productionGO:03269510.2IL10, IRAK3, TLR2
19negative regulation of interleukin-6 productionGO:03271510.2IL10, IRAK3, TLR4
20positive regulation of nitric-oxide synthase biosynthetic processGO:05177010.2TLR4, TLR2
21cellular response to mechanical stimulusGO:07126010.2IL18, TLR5, TLR4
22positive regulation of cytokine secretionGO:05071510.2TLR2, MIF, IL10
23negative regulation of tumor necrosis factor productionGO:03272010.2IL10, IRAK3, TLR4
24toll-like receptor signaling pathwayGO:00222410.2TLR10, TLR5, TLR2, TLR4
25positive regulation of interleukin-8 productionGO:03275710.1TLR4, TLR2, TLR5, IL18
26positive regulation of tissue remodelingGO:03410510.1IL15, IL18
27positive regulation of natural killer cell proliferationGO:03281910.1IL15, IL18
28I-kappaB phosphorylationGO:00725210.0TLR4, TLR2
29positive regulation of NF-kappaB transcription factor activityGO:0510929.9IRAK3, TLR2, TLR4
30positive regulation of interleukin-17 productionGO:0327409.8IL15, IL18
31MyD88-dependent toll-like receptor signaling pathwayGO:0027559.8TLR4, TLR2, TLR5, TLR10, TLR1, IRAK3
32cellular response to lipopolysaccharideGO:0712229.8TLR4, CSF3, IL10
33positive regulation of inflammatory responseGO:0507299.8TLR4, TLR2, TLR10, IL15, IL18
34negative regulation of growth of symbiont in hostGO:0441309.7IL10, TLR2
35innate immune responseGO:0450879.5TLR4, TLR2, TLR5, TLR10, TLR1, TREM1
36cell-cell signalingGO:0072679.4CXCL9, IL15, IL10, IL18
37immune responseGO:0069558.8TLR4, TLR2, TLR10, TLR1, CSF3, CXCL9
38inflammatory responseGO:0069548.6IL18, TLR2, TLR5, TLR10, TLR1, MIF

Molecular functions related to Melioidosis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1cytokine receptor bindingGO:0051269.9IL15, MIF
2lipopolysaccharide receptor activityGO:0018759.8TLR2, TLR4
3transmembrane signaling receptor activityGO:0048889.7TLR4, TLR2, TLR10, TLR1
4receptor activityGO:0048729.4TLR4, TLR2, TLR1, TREM1, PLAUR
5cytokine activityGO:0051258.7IL18, IL10, IL15, CXCL9, MIF, CSF3

Products for genes affiliated with Melioidosis

  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Melioidosis

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet