MCID: MLD001
MIFTS: 61

Melioidosis malady

Genetic diseases, Infectious diseases, Rare diseases categories

Aliases & Classifications for Melioidosis

About this section
Sources:
49OMIM, 10Disease Ontology, 47Novoseek, 12DISEASES, 51Orphanet, 2CDC, 65UMLS, 36MeSH, 59SNOMED-CT, 29ICD9CM, 28ICD10 via Orphanet, 37MESH via Orphanet, 66UMLS via Orphanet, 27ICD10
See all sources

Aliases & Descriptions for Melioidosis:

Name: Melioidosis 49 10 47 12 51 2 65 36
Whitmore's Disease 10 2
Acute and Fulminating Melioidosis 10
Subacute and Chronic Melioidosis 10
 
Nightcliff Gardener's Disease 10
Melioidosis, Unspecified 10
Pseudoglanders 10


Classifications:



Characteristics (Orphanet epidemiological data):

51
melioidosis:
Age of onset: All ages


External Ids:

OMIM49 615557
Disease Ontology10 DOID:5052
MeSH36 D008554
ICD9CM29 025
Orphanet51 31202
ICD10 via Orphanet28 A24.1, A24.2, A24.3 A24.4, more
MESH via Orphanet37 D008554
UMLS via Orphanet66 C0025229

Summaries for Melioidosis

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OMIM:49 Melioidosis is infection caused by the gram-negative, flagellated soil saprophyte Burkholderia pseudomallei, which is... (615557) more...

MalaCards based summary: Melioidosis, also known as whitmore's disease, is related to tuberculosis and hepatitis, and has symptoms including fever, respiratory distress and chest pain. An important gene associated with Melioidosis is TLR5 (Toll-Like Receptor 5), and among its related pathways are IKK complex recruitment mediated by RIP1 and MIF Action Through Endocytic Pathway. Affiliated tissues include lung, bone and skin, and related mouse phenotypes are adipose tissue and liver/biliary system.

Disease Ontology:10 A primary bacterial infectious disease that results in infection, has material basis in burkholderia pseudomallei, which is transmitted by contact with the contaminated water or soil. the infection has symptom fever, has symptom respiratory distress, has symptom chest pain, and has symptom stomach pain.

CDC:2 Melioidosis, also called Whitmore's disease, is an infectious disease that can infect humans or animals. The disease is caused by the bacterium Burkholderia pseudomallei.

Wikipedia:68 Melioidosis is an infectious disease caused by a gram-negative bacterium, Burkholderia pseudomallei,... more...

Related Diseases for Melioidosis

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Diseases related to Melioidosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 236)
idRelated DiseaseScoreTop Affiliating Genes
1tuberculosis30.2IFNG, IL10, IL6, TLR2
2hepatitis30.0IFNG, IL10, IL18
3pneumothorax29.3IL10, IL6, TLR2, TLR4, TLR5
4systemic lupus erythematosus29.3IFNG, IL10, IL18, IL6, TLR5
5glanders10.6
6pneumonia10.4
7splenic abscess10.4
8osteomyelitis10.3
9aneurysm10.3
10oculo cerebro acral syndrome10.3TLR1, TLR5
11arthritis10.3
12neutropenia chronic familial10.3TLR1, TLR2
13mycobacterium chelonae10.3TLR1, TLR2
14tuberculous empyema10.3IFNG, TLR4
15corneal granular dystrophy10.3TLR2, TLR4
16protein r deficiency10.2TLR2, TLR4
17best1 retinopathy10.2IFNG, IL18
18leptospirosis10.2
19septic arthritis10.2
20prostatitis10.2
21dentine erosion10.2IFNG, TLR4
22agel amyloidosis10.2TLR2, TLR4
23periocular meningioma10.2TLR2, TLR4
24ohtahara syndrome10.2IFNG, IL18
25bartholin's gland adenosquamous carcinoma10.2TLR1, TLR10
26common wart10.2TLR1, TLR10
27chronic polyneuropathy10.2TLR2, TLR4
28cystic fibrosis10.2
29necrotizing fasciitis10.2
30cerebritis10.2
31cellulitis10.2
32fasciitis10.2
33mediastinitis10.2
34pericarditis10.2
35primary bacterial infectious disease10.2
36anti-basement membrane glomerulonephritis10.2IFNG, TLR2, TLR5
37neonatal adrenoleukodystrophy10.2TLR2, TLR4
38supraglottis cancer10.2TLR2, TLR4, TLR5
39acute conjunctivitis10.2IFNG, TLR2, TLR4
40hyper-reninism10.1IFNG, TLR2, TLR4
41radiation cystitis10.1IFNG, TLR2, TLR4
42metagonimiasis10.1IFNG, TLR2, TLR4
43testicular leukemia10.1IFNG, IL6
44echinostomiasis10.1IFNG, IL6
45lower lip cancer10.1IL18, TLR2
46brucella suis brucellosis10.1IFNG, IL6
47migraine with aura10.1TLR2, TLR4
48intermediate malignant teratoma10.1IL6, TLR2
49humero-ulnar synostosis10.1IL18, IL6
50transient cerebral ischemia10.1TLR1, TLR10, TLR2

Graphical network of the top 20 diseases related to Melioidosis:



Diseases related to melioidosis

Symptoms for Melioidosis

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Clinical features from OMIM:

615557

Symptoms:

 10
  • fever
  • respiratory distress
  • chest pain
  • stomach pain

Drugs & Therapeutics for Melioidosis

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Drugs for Melioidosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Trimethoprimapproved147738-70-55578
Synonyms:
2,4-Diamino-5-(3,4,5-trimethoxybenzyl)pyrimidine
46984_FLUKA
46984_RIEDEL
5-[(3,4,5-Trimethoxyphenyl)methyl]-2,4-pyrimidinediamine
738-70-5
92131_FLUKA
92131_SIGMA
AB00052118
AB1004879
AC-13572
AC1L1KNQ
AC1Q48DF
AI3-52594
AKOS001650069
ARONIS24118
AZT + TMP/SMX (mixture) combination
Abacin
Abaprim
Alcorim-F
Alprim
Anitrim
Antrima
Antrimox
Apo-Sulfatrim
BB_SC-2116
BIDD:GT0190
BPBio1_000215
BRD-K07208025-001-06-5
BRN 0625127
BSPBio_000195
BSPBio_002245
BW 56-72
BW 5672
BW-56-72
Bacdan
Bacidal
Bacide
Bacin
Bacta
Bacterial
Bacterial [Antibiotic]
Bacticel
Bactin
Bactoprim
Bactramin
Bactrim
Bactrim DS
Bactrim Pediatric
Baktar
Bencole
Bethaprim
Biosulten
Briscotrim
C01965
CAS-738-70-5
CCRIS 2410
CHEBI:45924
CHEMBL22
CID5578
CPD0-1581
CPD000035999
Chemotrim
Chemotrin
Cidal
Co-Trimoxizole
Co-trimoxazole
Colizole
Colizole DS
Comox
Conprim
Cotrim
Cotrim D.S.
Cotrimel
D00145
D014295
DB00440
Deprim
DivK1c_000589
Drylin
Duocide
EINECS 212-006-2
EU-0101271
Esbesul
Espectrin
Euctrim
Eusaprim
Exbesul
Fectrim
Fermagex
Fortrim
Futin
Gantaprim
Gantrim
HMS1568J17
HMS1921I03
HMS2090D14
HMS2092A10
HMS501N11
HSDB 6781
I06-0086
IDI1_000589
Idotrim
Ikaprim
Imexim
Instalac
Ipral
KBio1_000589
KBio2_000647
KBio2_003215
KBio2_005783
KBio3_001465
KBioGR_000863
KBioSS_000647
KSC-4-158
KUC103659N
Kepinol
Kombinax
LS-1627
Lagatrim
Lagatrim Forte
Laratrim
Lastrim
Lidaprim
Linaris
Lopac-T-7883
Lopac0_001271
MLS000079023
MLS001201740
MLS002303068
Methoprim
Metoprim
Microtrim
MolPort-001-826-685
Monoprim
Monotrim
Monotrimin
NCGC00016055-01
NCGC00016055-02
NCGC00016055-06
NCGC00016055-12
NCGC00024707-01
NCGC00024707-03
NCGC00024707-04
NCGC00024707-05
NCGC00024707-06
NCGC00024707-07
NCGC00024707-08
NIH 204
 
NIH 204 (VAN)
NINDS_000589
NSC 106568
NSC-106568
NSC106568
Nopil
Novotrimel
Omstat
Oprea1_495058
Oraprim
Pancidim
Polytrim
Prestwick0_000208
Prestwick1_000208
Prestwick2_000208
Prestwick3_000208
Prestwick_485
Priloprim
Primosept
Primsol
Proloprim
Proloprim (TN)
Protrin
Purbal
Resprim
Resprim Forte
Roubac
Roubal
SAM002264649
SMP2_000262
SMR000035999
SPBio_000874
SPBio_002116
SPECTRUM1500595
STK177322
Salvatrim
Septra
Septra DS
Septra Grape
Septrin
Septrin DS
Septrin Forte
Septrin S
Setprin
Sigaprim
Sinotrim
Smz-Tmp
Spectrum2_000937
Spectrum3_000643
Spectrum4_000372
Spectrum5_001559
Spectrum_000167
Stopan
Streptoplus
Sugaprim
Sulfamar
Sulfamethoprim
Sulfamethoprim-DS
Sulfamethoxazole & Trimethoprim
Sulfatrim
Sulfatrim Pediatric
Sulfatrim-DS
Sulfatrim-SS
Sulfotrim
Sulfoxaprim
Sulmeprim
Sulmeprim Pediatric
Sulprim
Sulthrim
Sultrex
Sumetrolim
Supracombin
Suprim
Syraprim
T 7883
T2286
T7883_SIGMA
TCMDC-125538
TL8005108
TMP/SMX (MIXTURE))
Teleprim
Thiocuran
Tiempe
Tmp-Ratiopharm
Tocris-0650
Toprim
Trigonyl
Trimanyl
Trimesulf
Trimeth/Sulfa
Trimethioprim
Trimethopim(TMP)
Trimethoprim
Trimethoprim & VRC3375
Trimethoprim (JAN/USP/INN)
Trimethoprim [USAN:BAN:INN:JAN]
Trimethoprime
Trimethoprime [INN-French]
Trimethoprimum
Trimethoprimum [INN-Latin]
Trimethopriom
Trimetoprim
Trimetoprim [DCIT]
Trimetoprim [Polish]
Trimetoprima
Trimetoprima [INN-Spanish]
Trimexazole
Trimexol
Trimez-IFSA
Trimezol
Trimogal
Trimono
Trimopan
Trimpex
Trimpex (TN)
Trimpex 200
Triméthoprime
Triprim
Trisul
Trisulcom
Trisulfam
Trisural
U-Prin
UNII-AN164J8Y0X
UPCMLD-DP132
UPCMLD-DP132:001
Unitrim
Uretrim
Uro-D S
Uro-Septra
Urobactrim
Uroplus
Uroplus DS
Uroplus SS
Utetrin
Velaten
WLN: T6N CNJ BZ DZ E1R CO1 DO1 EO1
WR 5949
Wellcoprim
Wellcoprin
Xeroprim
ZINC06627681
Zamboprim
component of Bactrim
component of Septra
nchembio.108-comp1
nchembio.215-comp11
nchembio.221-comp23
trimethoprim
2
Ceftazidimeapproved5578439-06-25481173
Synonyms:
(6R,7R)-7-({(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(1-carboxy-1-methylethoxy)imino]acetyl}amino)-8-oxo-3-(pyridinium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
(6R,7R)-7-[[(2E)-2-(2-amino-1,3-thiazol-4-yl)-2-(1-hydroxy-2-methyl-1-oxopropan-2-yl)oxyiminoacetyl]amino]-8-oxo-3-(pyridin-1-ium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
(6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(1-hydroxy-2-methyl-1-oxopropan-2-yl)oxyiminoacetyl]amino]-8-oxo-3-(pyridin-1-ium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
(6R,7R)-7-[[2-(2-amino-1,3-thiazol-4-yl)-2-(1-hydroxy-2-methyl-1-oxopropan-2-yl)oxyiminoacetyl]amino]-8-oxo-3-(pyridin-1-ium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
(6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino}-8-oxo-3-(pyridinium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
7-[[2-(2-amino-1,3-thiazol-4-yl)-2-(1-hydroxy-2-methyl-1-oxopropan-2-yl)oxyiminoacetyl]amino]-8-oxo-3-(pyridin-1-ium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
72558-82-8
7beta-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino}-3-(pyridinium-1-ylmethyl)-3,4-didehydrocepham-4-carboxylate
AB00513848
AC1L1E5K
AC1L3MNA
AC1NUK7U
AC1NUN9Q
BIDD:GT0734
BRN 4344904
C06889
C2225
C22H22N6O7S2
CAZ
CEFTAZIDIME (ARGININE FORMULATION)
CHEBI:3508
CHEMBL201
CID2650
CID5481173
CID5484131
Ceftazidim
 
Ceftazidima
Ceftazidima [INN-Spanish]
Ceftazidime
Ceftazidime (INN)
Ceftazidime (TN)
Ceftazidime Sodium In Plastic Container
Ceftazidime anhydrous
Ceftazidime pentahydrate
Ceftazidimum
Ceftazidimum [INN-Latin]
Ceptaz
Ceptaz (TN)
D07654
DB00438
EINECS 276-715-9
Fortaz
Fortaz (TN)
Fortaz In Plastic Container
HMS2090M13
I06-1102
LS-132194
SN 401
Tazicef
UNII-9M416Z9QNR
ceftazidima
ceftazidime
ceftazidimum
3
Sulfamethoxazoleapproved134723-46-65329
Synonyms:
129378-89-8
3-(Para-Aminophenylsulphonamido)-5-methylisoxazole
3-(p-Aminobenzenesulfonamido)-5-methylisoxazole
3-(p-Aminophenylsulfonamido)-5-methylisoxazole
3-(para-Aminophenylsulphonamido)-5-methylisoxazole
3-Sulfanilamido-5-methylisoxazole
3-Sulphanilamido-5-methylisoxazole
4-Amino-N-(5-methyl-1,2-oxazol-3-yl)benzenesulfonamide
4-Amino-N-(5-methyl-3-isoxazolyl)-Benzenesulfonamide
4-Amino-N-(5-methyl-3-isoxazolyl)benzenesulfonamide
4-Amino-N-(5-methyl-isoxazol-3-yl)-benzenesulfonamide
4-Amino-N-[5-methyl-3- isoxazolyl]benzenesulfonamide
4-amino-N-(5-methyl-1,2-oxazol-3-yl)benzenesulfonamide
4-amino-N-(5-methylisoxazol-3-yl)benzenesulfonamide
46850_RIEDEL
5-Methyl-3-sulfanilamidoisoxazole
5-Methyl-3-sulfanylamidoisoxazole
5-Methyl-3-sulfonylamidoisoxazole
5-Methyl-3-sulphanil-amidoisoxazole
723-46-6
A047
AB00052099
AC-11118
AC1L1K42
AC1Q2J5R
AKOS000200952
ALBB-002089
ARONIS018156
Apo-Sulfamethoxazole
Azo Gantanol
Azo-Gantanol
Azo-gantanol
BAS 00836086
BB_SC-1251
BIDD:GT0731
BPBio1_000081
BRD-K28494619-001-05-0
BRN 0226453
BSPBio_000073
BSPBio_002028
Bactrim
Bactrimel
C07315
C10H11N3O3S
CAS-723-46-6
CCRIS 567
CHEBI:9332
CHEMBL443
CID5329
CPD000058223
D00447
D013420
DB01015
DivK1c_000649
EINECS 211-963-3
Gamazole
Gantanol
Gantanol (TN)
Gantanol (tn)
Gantanol-DS
HMS1568D15
HMS1921A21
HMS2092K03
HMS502A11
HMS561O18
HSDB 3186
I01-0154
IDI1_000649
InChI=1/C10H11N3O3S/c1-7-6-10(12-16-7)13-17(14,15)9-4-2-8(11)3-5-9/h2-6H,11H2,1H3,(H,12,13)
KBio1_000649
KBio2_001474
KBio2_004042
KBio2_006610
KBio3_001528
KBioGR_000749
KBioSS_001474
LS-1620
MLS000069732
MLS001055354
MLS001074165
MS 53
Maybridge1_007190
Metoxal
MolPort-000-145-787
N'-(5-Methyl-3-isoxazole)sulfanilamide
 
N'-(5-Methyl-3-isoxazolyl)-Sulfanilamide
N'-(5-Methyl-3-isoxazolyl)sulfanilamide
N'-(5-Methylisoxazol-3-yl)sulphanilamide
N(Sup1)-(5-Methyl-3-isoxazolyl)sulfanilamide
N(sup 1)-(5-Methyl-3-isoxazolyl)sulfanilamide
N(sup 1)-(5-Methyl-3-isoxazolyl)sulphanilamide
N(sup1)-(5-Methyl-3-isoxazolyl)sulfanilamide
N1-(5-Methyl-3-isoxazolyl)sulfanilamide
N1-(5-Methyl-3-isoxazolyl)sulphanilamide
N1-(5-Methylisoxazol-3-yl)sulfanilamide
N1-(5-methyl-3-isoxazolyl)-Sulfanilamide
NCGC00016533-01
NCGC00016533-02
NCGC00021995-03
NCGC00021995-04
NCGC00021995-05
NINDS_000649
NSC 147832
NSC147832
N^1-(5-Methyl-3-isoxazolyl)-Sulfanilamide
Ndimethyl1-(5-methyl-3-isoxazolyl)-Sulfanilamide
Oprea1_114486
Oprea1_285680
Prestwick0_000177
Prestwick1_000177
Prestwick2_000177
Prestwick3_000177
Prestwick_453
Radonil
Ro 4-2130
Ro 6-2580/11
Ro-4-2130
S0361
S1915_Selleck
S7507_FLUKA
S7507_SIGMA
SAM002554930
SIM
SMR000058223
SMX
SPBio_000896
SPBio_001994
SPECTRUM1500550
STK007988
SULFAMETHOXAZOLE (8064-90-2 (TRIMETHOPRIM/SULFAMETHOXAZOLE)
Septran
Simsinomin
Sinomin
Solfametossazolo
Solfametossazolo [DCIT]
Spectrum2_000788
Spectrum3_000584
Spectrum4_000345
Spectrum5_000982
Spectrum_000994
Sulfamethalazole
Sulfamethoxazol
Sulfamethoxazole
Sulfamethoxazole (JP15/USP/INN)
Sulfamethoxazole [USAN:INN:JAN]
Sulfamethoxazole sodium
Sulfamethoxazole(USAN)
Sulfamethoxazolum
Sulfamethoxazolum [INN-Latin]
Sulfamethoxizole
Sulfamethylisoxazole
Sulfametoxazol
Sulfametoxazol [INN-Spanish]
Sulfanilamide, N1-(5-methyl-3-isoxazolyl)- (8CI)
Sulfisomezole
Sulpha-Methoxizole
Sulpha-methoxizole
Sulphamethalazole
Sulphamethoxazol
Sulphamethoxazole
Sulphamethoxazole BP 98
Sulphamethylisoxazole
Sulphisomezole
TL8005058
TMP/SMX (MIXTURE))
Trib
UNII-JE42381TNV
Urobak
WLN: T5NOJ C1 EMSWR DZ
ZINC00089763
nchembio.221-comp24
sulfamethoxazole
4
Meropenemapproved, investigational78119478-56-764778, 441130
Synonyms:
(1R,5S,6S)-2-[(3S,5S)-5-(dimethylaminocarbonyl)pyrrolidin-3-ylthio]-6-[(R)-1-hydroxyethyl]-1-methylcarbapen-2-em-3-carboxylic acid trihydrate
(1R,5S,6S)-2-[(3S,5S)-5-DIMETHYLAMINOCARBONYLPYRROLIDIN-3-ylthio]-6-[(R)-1-hydroxyethyl]-1-methylcarbapen-2-em-3-carboxylic acid
(2S,3R,4R)-2-[(1S,2R)-1-carboxy-2-hydroxypropyl]-4-{[(3S,5R)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-3-methyl-3,4-dihydro-2H-pyrrole-5-carboxylic acid
(4R,5S,6S)-3-[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
(4R,5S,6S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]thio}-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
(5S,6S)-3-((3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-ylthio)-6-((S)-1-hydroxyethyl)-4-methyl-7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid
(6S)-2-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-6-[(1R)-1-hydroxyethyl]-1beta-methyl-2,3-didehydro-1-carbapenam-3-carboxylic acid
96036-03-2
AB00514051
AB1004614
AC1L9ALL
Ambap119478-56-7
Antibiotic SM 7338
Antibiotic sm 7338
BIDD:GT0851
BPBio1_001334
BSPBio_001212
CHEBI:43968
CHEMBL127
CID441130
CPD000469184
D08185
HMS1571M14
HMS2051G08
HMS2090C05
 
ICI-194660
MEPM
MERONEM
MLS001401437
Meronem (TN)
Meropen
Meropenem
Meropenem (INN)
Meropenem Hydrate
Meropenem anhydrous
Meropenem trihydrate
Meropenemum
Meropenemum [INN-Latin]
Meropenemum trihydricum
Merrem
Merrem I.V. (TN)
Merrem IV
MolPort-006-709-417
NCGC00179259-01
Prestwick0_001106
Prestwick1_001106
Prestwick2_001106
Prestwick3_001106
SAM001246650
SM-7338
SMR000469184
SPBio_003086
5Trimethoprim-Sulfamethoxazole Combination153

Interventional clinical trials:

idNameStatusNCT IDPhase
1A Single-blind Stepped Wedge Cluster Randomized Controlled Behaviour Change Trial to Determine Effectiveness of Prevention Programme of Melioidosis in Diabetics in Ubon Ratchathani, Northeast ThailandRecruitingNCT02089152
2Study to Obtain Blood Samples to Improve the Diagnosis of MelioidosisRecruitingNCT02668406
3A Randomized Double Blinded Comparison of Ceftazidime and Meropenem in Severe MelioidosisRecruitingNCT00579956
4Co-trimoxazole as Maintenance Therapy for MeliodosisRecruitingNCT01420341
5Rapid Diagnostic Tests and Clinical/Laboratory Predictors of Tropical Diseases In Patients With Persistent Fever in Cambodia, Nepal, Democratic Republic of the Congo and Sudan (NIDIAG-Fever)Active, not recruitingNCT01766830

Search NIH Clinical Center for Melioidosis


Cochrane evidence based reviews: Melioidosis

Genetic Tests for Melioidosis

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Anatomical Context for Melioidosis

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MalaCards organs/tissues related to Melioidosis:

33
Lung, Bone, Skin, T cells, Testes, B cells, Breast

Animal Models for Melioidosis or affiliated genes

About this section

MGI Mouse Phenotypes related to Melioidosis:

38 (show all 14)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053759.0IL18, IL6, TLR2, TLR4, TLR5
2MP:00053707.9IFNG, IL10, IL6, TLR2, TLR4, TLR5
3MP:00020067.9IFNG, IL10, IL6, TLR2, TLR4
4MP:00053697.8IFNG, IL10, IL18, IL6, TLR2, TLR4
5MP:00053907.8IFNG, IL10, IL6, IRAK3, TLR2, TLR4
6MP:00053887.8IFNG, IL10, IL6, TLR2, TLR4, TLR5
7MP:00107717.6IFNG, IL10, IL18, IL6, TLR2, TLR4
8MP:00053817.6IFNG, IL10, IL18, IL6, TLR2, TLR4
9MP:00053847.6IFNG, IL10, IL18, IL6, TLR2, TLR4
10MP:00053857.5IFNG, IL10, IL18, IL6, TLR2, TLR4
11MP:00053867.1IFNG, IL10, IL18, IL6, TLR2, TLR4
12MP:00053786.9IFNG, IL10, IL18, IL6, IRAK3, TLR2
13MP:00053975.9IFNG, IL10, IL18, IL6, IRAK3, LY96
14MP:00053875.6IFNG, IL10, IL18, IL6, IRAK3, LY96

Publications for Melioidosis

About this section

Articles related to Melioidosis:

(show top 50)    (show all 568)
idTitleAuthorsYear
1
T-Cell Responses Are Associated with Survival in Acute Melioidosis Patients. (26495852)
2015
2
Cutaneous melioidosis. (26370124)
2015
3
Cutaneous melioidosis with unusual histological features. (26299451)
2015
4
Unusual Presentation of Melioidosis in a Case of Pseudoaneurysm of Descending Thoracic Aorta: Review of Two Case Reports. (26380820)
2015
5
Melioidosis: a report of two cases. (25668164)
2014
6
The Role of NOD2 in Murine and Human Melioidosis. (24298015)
2014
7
Induction of mouse melioidosis with meningitis by CD11b+ phagocytic cells harboring intracellular B. pseudomallei as a Trojan horse. (23951382)
2013
8
Melioidosis: refining management of a tropical time bomb. (24284288)
2013
9
Antimicrobial Prophylaxis For Melioidosis and Leptospirosis For At Risk Rescue Workers. (23466779)
2013
10
Melioidosis from contaminated bore water and successful UV sterilization. (23751401)
2013
11
Melioidosis as a consequence of sporting activity. (23732257)
2013
12
Expect the unexpected: pleuro-pulmonary melioidosis in a renal transplant recipient. (23278969)
2013
13
Melioidosis breast abscesses. (22285589)
2012
14
Melioidosis in animals, Thailand, 2006-2010. (22304782)
2012
15
Outbreak of melioidosis and leptospirosis co-infection following a rescue operation. (23082420)
2012
16
Development of hydrolysis probe-based real-time PCR for identification of virulent gene targets of Burkholderia pseudomallei and B. mallei--a retrospective study on archival cases of service members with melioidosis and glanders. (22360070)
2012
17
Development of capsular polysaccharide-based glycoconjugates for immunization against melioidosis and glanders. (22912938)
2012
18
BLF1, the first Burkholderia pseudomallei toxin, connects inhibition of host protein synthesis with melioidosis. (22817745)
2012
19
Imported melioidosis in France revealed by a cracking abdominal mycotic aortic aneurysm in a 61-year-old man. (22962397)
2012
20
Lipopolysaccharide from Burkholderia thailandensis E264 provides protection in a murine model of melioidosis. (20837078)
2010
21
Radiological manifestations of melioidosis. (20103424)
2010
22
Imported melioidosis in Danish travellers: a diagnostic challenge. (20297927)
2010
23
Burkholderia thailandensis whole cell antigen cross-reacts with B. pseudomallei antibodies from patients with melioidosis in an immunofluorescent assay. (20578523)
2010
24
Genomic transcriptional profiling identifies a candidate blood biomarker signature for the diagnosis of septicemic melioidosis. (19903332)
2009
25
The molecular and cellular basis of pathogenesis in melioidosis: how does Burkholderia pseudomallei cause disease? (19732156)
2009
26
Melioidosis in a tropical city state, Singapore. (19861063)
2009
27
Non-septicemic melioidosis presenting as cardiac tamponade. (18784243)
2008
28
Rheumatological manifestations in patients with melioidosis. (19058601)
2008
29
Cases of melioidosis in a university teaching hospital in Malaysia. (18473106)
2008
30
Melioidosis--an unusual cause of septic arthritis. (18506568)
2008
31
Evaluation of recombinant antigens for diagnosis of melioidosis. (18657105)
2008
32
Serum C-reactive protein and liver disease in patients with melioidosis. (17262186)
2007
33
Misdiagnosing melioidosis. (17479916)
2007
34
Melioidosis outbreak after typhoon, southern Taiwan. (17553230)
2007
35
Melioidosis: an under-diagnosed entity in western coastal India: a clinico-microbiological analysis. (17901643)
2007
36
Role of selective and nonselective media for isolation of Burkholderia pseudomallei from throat swabs of patients with melioidosis. (16757651)
2006
37
Imported melioidosis--South Florida, 2005. (16915220)
2006
38
Fatal septicemic melioidosis in a young military person possibly co-infected with Leptospira interrogans and Orientia tsutsugamushi. (15909673)
2005
39
Melioidosis of the spleen diagnosed by 16S rDNA amplification and sequencing. (16012017)
2005
40
Antibodies from patients with melioidosis recognize Burkholderia mallei but not Burkholderia thailandensis antigens in the indirect hemagglutination assay. (16145163)
2005
41
Melioidosis in Pahang, Malaysia. (16515112)
2005
42
Melioidosis and the vascular surgeon: Hospital Kuala Lumpur experience. (16234087)
2005
43
Clinical presentation of melioidosis in Queensland, Australia. (16111729)
2005
44
Melioidosis in animals: a review on epizootiology, diagnosis and clinical presentation. (15525357)
2004
45
Multilocus sequence typing and evolutionary relationships among the causative agents of melioidosis and glanders, Burkholderia pseudomallei and Burkholderia mallei. (12734250)
2003
46
Melioidosis presenting as an infected intrathoracic subclavian artery pseudoaneurysm treated with femoral vein interposition graft. (11877708)
2002
47
Melioidosis vaccines. (12901586)
2002
48
Cutaneous melioidosis. (12139670)
2002
49
Randomized, double-blind, controlled study of cefoperazone-sulbactam plus cotrimoxazole versus ceftazidime plus cotrimoxazole for the treatment of severe melioidosis. (11389491)
2001
50
Immune cell activation in melioidosis: increased serum levels of interferon-gamma and soluble interleukin-2 receptors without change in soluble CD8 protein. (1902247)
1991

Variations for Melioidosis

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Expression for genes affiliated with Melioidosis

About this section
LifeMap Discovery
Genes differentially expressed in tissues of Melioidosis patients vs. healthy controls: 32 (show all 181)
id Gene Description Tissue Up/Dn Fold Change (log2) P value
1CD177CD177 moleculeBlood+8.410.000
2ZDHHC19zinc finger, DHHC-type containing 19Blood+6.910.000
3MMP8matrix metallopeptidase 8Blood+6.490.000
4SLC51Asolute carrier family 51, alpha subunitBlood+6.460.000
5HPhaptoglobinBlood+6.230.000
6FCER1AFc fragment of IgE, high affinity I, receptor for; alpha polypeptideBlood-6.000.000
7GPR84G protein-coupled receptor 84Blood+5.860.000
8ANKRD22ankyrin repeat domain 22Blood+5.720.000
9OLAHoleoyl-ACP hydrolaseBlood+5.540.000
10LRRN3leucine rich repeat neuronal 3Blood-5.510.000
11PCOLCE2procollagen C-endopeptidase enhancer 2Blood+5.470.000
12C1QCcomplement component 1, q subcomponent, C chainBlood+5.420.000
13PFKFB26-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2Blood+5.390.000
14CCNA1cyclin A1Blood+5.140.000
15C1QBcomplement component 1, q subcomponent, B chainBlood+5.090.000
16LINC00668long intergenic non-protein coding RNA 668Blood+4.990.000
17CACNA1Ecalcium channel, voltage-dependent, R type, alpha 1E subunitBlood+4.980.000
18FGF13fibroblast growth factor 13Blood+4.960.000
19NOVnephroblastoma overexpressedBlood-4.840.000
20PLVAPplasmalemma vesicle associated proteinBlood-4.760.000
21KLklothoBlood+4.740.000
22SLCO4A1solute carrier organic anion transporter family, member 4A1Blood+4.730.000
23MYO10myosin XBlood+4.680.000
24SLC1A3solute carrier family 1 (glial high affinity glutamate transporter), member 3Blood+4.680.000
25RPGRIP1retinitis pigmentosa GTPase regulator interacting protein 1Blood-4.670.000
26RETNresistinBlood+4.650.000
27CD274CD274 moleculeBlood+4.440.000
28MCEMP1mast cell-expressed membrane protein 1Blood+4.440.000
29BMXBMX non-receptor tyrosine kinaseBlood+4.410.000
30SERPINA1serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1Blood+4.380.000
31CEACAM1carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)Blood+4.380.000
32GRB10growth factor receptor-bound protein 10Blood+4.370.000
33CACNA2D3calcium channel, voltage-dependent, alpha 2/delta subunit 3Blood-4.250.000
34LINC01220long intergenic non-protein coding RNA 1220Blood+4.200.000
35LTFlactotransferrinBlood+4.190.000
36SLC26A8solute carrier family 26 (anion exchanger), member 8Blood+4.180.000
37ARG1arginase 1Blood+4.170.000
38IL18R1interleukin 18 receptor 1Blood+4.170.000
39IL1R2interleukin 1 receptor, type IIBlood+4.080.000
40SLC2A11solute carrier family 2 (facilitated glucose transporter), member 11Blood+4.060.000
41CFHcomplement factor HBlood+4.030.000
42G0S2G0/G1 switch 2Blood+4.020.000
43MMP9matrix metallopeptidase 9Blood+3.970.000
44FCARFc fragment of IgA receptorBlood+3.940.000
45SCN9Asodium channel, voltage gated, type IX alpha subunitBlood+3.940.000
46FAM20Afamily with sequence similarity 20, member ABlood+3.940.000
47KRTAP19-6keratin associated protein 19-6Blood+3.930.000
48TDRD9tudor domain containing 9Blood+3.920.000
49KREMEN1kringle containing transmembrane protein 1Blood+3.860.000
50HSD3B7hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7Blood+3.840.000
51CR1complement component (3b/4b) receptor 1 (Knops blood group)Blood+3.830.000
52VNN1vanin 1Blood+3.820.000
53LGALSLlectin, galactoside-binding-likeBlood-3.810.000
54COL17A1collagen, type XVII, alpha 1Blood+3.810.000
55NELL2neural EGFL like 2Blood-3.790.000
56SLAMF8SLAM family member 8Blood+3.790.000
57ELOVL4ELOVL fatty acid elongase 4Blood-3.760.000
58BATF2basic leucine zipper transcription factor, ATF-like 2Blood+3.760.000
59C1QAcomplement component 1, q subcomponent, A chainBlood+3.750.000
60ANKRD34Bankyrin repeat domain 34BBlood+3.740.000
61NTSR1neurotensin receptor 1 (high affinity)Blood+3.740.000
62NAIPNLR family, apoptosis inhibitory proteinBlood+3.740.000
63TNFAIP8L3tumor necrosis factor, alpha-induced protein 8-like 3Blood+3.720.000
64LOC55338uncharacterized LOC55338Blood+3.720.000
65KIAA1671KIAA1671Blood-3.680.000
66PTGDR2prostaglandin D2 receptor 2Blood-3.680.000
67BCL6B-cell CLL/lymphoma 6Blood+3.660.000
68IL5RAinterleukin 5 receptor, alphaBlood-3.660.000
69METTL7Bmethyltransferase like 7BBlood+3.650.000
70PTGDRprostaglandin D2 receptor (DP)Blood-3.630.000
71CD160CD160 moleculeBlood-3.620.000
72GALNT14polypeptide N-acetylgalactosaminyltransferase 14Blood+3.600.000
73AP3B2adaptor-related protein complex 3, beta 2 subunitBlood+3.580.000
74GCATglycine C-acetyltransferaseBlood-3.580.000
75ANXA3annexin A3Blood+3.560.000
76DAAM2dishevelled associated activator of morphogenesis 2Blood+3.550.000
77CLEC4CC-type lectin domain family 4, member CBlood-3.550.000
78CD248CD248 molecule, endosialinBlood-3.550.000
79SERPING1serpin peptidase inhibitor, clade G (C1 inhibitor), member 1Blood+3.540.000
80TCN2transcobalamin IIBlood+3.540.000
81PLEKHG4pleckstrin homology domain containing, family G (with RhoGef domain) member 4Blood-3.530.000
82GBP6guanylate binding protein family, member 6Blood+3.530.000
83HDChistidine decarboxylaseBlood-3.520.000
84TCTEX1D1Tctex1 domain containing 1Blood+3.520.000
85LINC00937long intergenic non-protein coding RNA 937Blood+3.510.000
86PID1phosphotyrosine interaction domain containing 1Blood-3.500.000
87PIM3Pim-3 proto-oncogene, serine/threonine kinaseBlood+3.490.000
88CD3DCD3d molecule, delta (CD3-TCR complex)Blood-3.480.000
89CARD17caspase recruitment domain family, member 17Blood+3.470.000
90MAP2K6mitogen-activated protein kinase kinase 6Blood+3.450.000
91SUPT3HSPT3 homolog, SAGA and STAGA complex componentBlood-3.430.000
92BPIbactericidal/permeability-increasing proteinBlood+3.420.000
93LIPMlipase, family member MBlood+3.420.000
94LGALS2lectin, galactoside-binding, soluble, 2Blood-3.420.000
95KLHL3kelch-like family member 3Blood-3.400.000
96UGCGUDP-glucose ceramide glucosyltransferaseBlood+3.400.000
97SPINK2serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)Blood-3.400.000
98OLIG2oligodendrocyte lineage transcription factor 2Blood-3.390.000
99KCNJ15potassium channel, inwardly rectifying subfamily J, member 15Blood+3.390.000
100DBPD site of albumin promoter (albumin D-box) binding proteinBlood-3.380.000
101PRSS23protease, serine, 23Blood-3.380.000
102MUC1mucin 1, cell surface associatedBlood+3.370.000
103NT5E5'-nucleotidase, ecto (CD73)Blood-3.360.000
104TROtrophininBlood+3.350.000
105UG0898H09uncharacterized LOC643763Blood+3.350.000
106ZNF69zinc finger protein 69Blood-3.350.000
107AIM2absent in melanoma 2Blood+3.340.000
108PFKFB36-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3Blood+3.310.000
109DNASE1L3deoxyribonuclease I-like 3Blood-3.310.000
110FHITfragile histidine triadBlood-3.310.000
111MT1Gmetallothionein 1GBlood+3.300.000
112STOMstomatinBlood+3.300.000
113CFBcomplement factor BBlood+3.300.000
114MIR205HGMIR205 host geneBlood+3.300.000
115KIF20Akinesin family member 20ABlood+3.290.000
116LINC00342long intergenic non-protein coding RNA 342Blood+3.290.000
117GSTM1glutathione S-transferase mu 1Blood-3.290.000
118NECAB1N-terminal EF-hand calcium binding protein 1Blood+3.270.000
119HGFhepatocyte growth factor (hepapoietin A; scatter factor)Blood+3.260.000
120CEACAM8carcinoembryonic antigen-related cell adhesion molecule 8Blood+3.260.000
121TMOD3tropomodulin 3 (ubiquitous)Blood+3.240.000
122SIGLEC17Psialic acid binding Ig-like lectin 17, pseudogeneBlood-3.240.000
123APOL1apolipoprotein L, 1Blood+3.240.000
124HLA-DQB1major histocompatibility complex, class II, DQ beta 1Blood-3.240.000
125MS4A4Amembrane-spanning 4-domains, subfamily A, member 4ABlood+3.230.000
126OLFM1olfactomedin 1Blood-3.230.000
127ENTPD7ectonucleoside triphosphate diphosphohydrolase 7Blood+3.220.000
128GPR141G protein-coupled receptor 141Blood+3.220.000
129ZAKsterile alpha motif and leucine zipper containing kinase AZKBlood+3.220.000
130EDARectodysplasin A receptorBlood-3.210.000
131IL27interleukin 27Blood+3.210.000
132OPLAH5-oxoprolinase (ATP-hydrolysing)Blood+3.210.000
133OLFM4olfactomedin 4Blood+3.200.000
134TNFAIP6tumor necrosis factor, alpha-induced protein 6Blood+3.200.000
135TIFATRAF-interacting protein with forkhead-associated domainBlood+3.190.000
136IRAK3interleukin-1 receptor-associated kinase 3Blood+3.190.000
137DTX3deltex 3, E3 ubiquitin ligaseBlood-3.190.000
138VSIG4V-set and immunoglobulin domain containing 4Blood+3.190.000
139PDCD1LG2programmed cell death 1 ligand 2Blood+3.190.000
140LILRA5leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5Blood+3.190.000
141S100A12S100 calcium binding protein A12Blood+3.190.000
142SOCS3suppressor of cytokine signaling 3Blood+3.180.000
143VIPR1vasoactive intestinal peptide receptor 1Blood-3.170.000
144EBI3Epstein-Barr virus induced 3Blood+3.170.000
145ENKURenkurin, TRPC channel interacting proteinBlood-3.150.000
146LIMK2LIM domain kinase 2Blood+3.150.000
147CCDC65coiled-coil domain containing 65Blood-3.150.000
148FBLN2fibulin 2Blood-3.150.000
149LRRN1leucine rich repeat neuronal 1Blood+3.150.000
150APOL6apolipoprotein L, 6Blood+3.140.000
151ACVR1Bactivin A receptor, type IBBlood+3.140.000
152CPA3carboxypeptidase A3 (mast cell)Blood-3.140.000
153KLF5Kruppel-like factor 5 (intestinal)Blood+3.140.000
154CD1CCD1c moleculeBlood-3.120.000
155OTOFotoferlinBlood+3.120.000
156CD8BCD8b moleculeBlood-3.120.000
157LINC01138long intergenic non-protein coding RNA 1138Blood+3.110.000
158LYRM4LYR motif containing 4Blood-3.100.000
159KIF1Bkinesin family member 1BBlood+3.100.000
160EPHA4EPH receptor A4Blood-3.090.000
161SLC2A14solute carrier family 2 (facilitated glucose transporter), member 14Blood+3.090.000
162CCR3chemokine (C-C motif) receptor 3Blood-3.090.000
163SFTPDsurfactant protein DBlood-3.090.000
164HIST2H2ABhistone cluster 2, H2abBlood+3.080.000
165RALGAPA2Ral GTPase activating protein, alpha subunit 2 (catalytic)Blood+3.080.000
166WDFY3WD repeat and FYVE domain containing 3Blood+3.080.000
167SELMselenoprotein MBlood-3.070.000
168APOBEC3Bapolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3BBlood+3.070.000
169KLRC3killer cell lectin-like receptor subfamily C, member 3Blood-3.050.000
170EPHB1EPH receptor B1Blood-3.040.000
171LDLRAD4low density lipoprotein receptor class A domain containing 4Blood-3.030.000
172CLEC4DC-type lectin domain family 4, member DBlood+3.030.000
173MGAMmaltase-glucoamylaseBlood+3.020.000
174TGFBItransforming growth factor, beta-induced, 68kDaBlood-3.020.000
175MAPK14mitogen-activated protein kinase 14Blood+3.020.000
176NHSNance-Horan syndrome (congenital cataracts and dental anomalies)Blood-3.010.000
177C2complement component 2Blood+3.010.000
178MKNK1MAP kinase interacting serine/threonine kinase 1Blood+3.010.000
179PLSCR4phospholipid scramblase 4Blood+3.010.000
180CABP5calcium binding protein 5Blood-3.000.000
181FAM225Afamily with sequence similarity 225, member A (non-protein coding)Blood+3.000.000

Search GEO for disease gene expression data for Melioidosis.

Pathways for genes affiliated with Melioidosis

About this section

Pathways related to Melioidosis according to GeneCards Suite gene sharing:

(show all 47)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.7LY96, TLR4
29.7LY96, TLR4
39.6IFNG, IL18
49.6IFNG, IL18
59.3IFNG, IL6
6
Show member pathways
9.3IL6, TLR2, TLR5
79.2IRAK3, LY96, TLR4
89.1IFNG, IL10
9
Show member pathways
9.1IL6, LY96, TLR4
109.0IFNG, IL6, TLR4
119.0IFNG, IL6, TLR4
129.0IFNG, IL18, TLR2, TLR4
13
Show member pathways
8.8TLR1, TLR10, TLR2, TLR4, TLR5
148.8TLR1, TLR10, TLR2, TLR4, TLR5
15
TNF Signaling (sino)
Show member pathways
8.8TLR1, TLR10, TLR2, TLR4, TLR5
168.7IL10, IL6, TLR4
178.6IL18, IL6, TLR2, TLR4, TLR5
188.5IFNG, IL10, IL6
19
Show member pathways
8.5IFNG, IL10, IL6
20
Show member pathways
8.4LY96, TLR1, TLR10, TLR2, TLR4, TLR5
21
Show member pathways
8.4LY96, TLR1, TLR10, TLR2, TLR4, TLR5
22
Salmonella infection (KEGG)
Show member pathways
8.4LY96, TLR1, TLR10, TLR2, TLR4, TLR5
23
Show member pathways
8.3IFNG, IL18, IL6, TLR2, TLR4
248.3IFNG, IL18, IL6, TLR2, TLR4
258.3IL10, IL6, LY96, TLR4
268.1IFNG, IL10, IL18, IL6
27
Show member pathways
8.1IFNG, IL10, IL18, IL6
28
Show member pathways
8.1IFNG, IL10, IL18, IL6
29
Show member pathways
8.1IFNG, IL10, LY96, TLR2, TLR4
30
Show member pathways
8.0IFNG, IL6, IRAK3, LY96, TLR4
317.9IFNG, IL10, IL6, TLR2, TLR4
32
Show member pathways
7.8IRAK3, LY96, TLR1, TLR10, TLR2, TLR4
33
Show member pathways
7.8IRAK3, LY96, TLR1, TLR10, TLR2, TLR4
34
Show member pathways
7.8IFNG, IRAK3, TLR1, TLR10, TLR2, TLR4
357.7IFNG, IL6, TLR1, TLR10, TLR2, TLR4
36
Show member pathways
7.7IFNG, IL6, TLR1, TLR10, TLR2, TLR4
37
Show member pathways
7.7IL6, IRAK3, TLR1, TLR10, TLR2, TLR4
387.6IFNG, IL10, IRAK3, TLR1, TLR2, TLR4
397.5IFNG, IL10, IL18, IL6, TLR2, TLR4
40
Show member pathways
7.4IL18, IL6, LY96, TLR1, TLR10, TLR2
41
Show member pathways
7.2IFNG, IL10, IL18, IL6, TLR2, TLR4
427.2IFNG, IL10, IL18, IL6, TLR1, TLR2
43
Show member pathways
7.1IFNG, IL6, IRAK3, LY96, TLR1, TLR2
44
Show member pathways
6.8IFNG, IL10, IL6, LY96, TLR1, TLR2
45
Show member pathways
6.5IFNG, IL10, IL18, IL6, TLR1, TLR10
46
Show member pathways
6.5IL10, IL18, IL6, IRAK3, TLR1, TLR10
47
Show member pathways
6.3IFNG, IL18, IL6, IRAK3, LY96, TLR1

GO Terms for genes affiliated with Melioidosis

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Cellular components related to Melioidosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1Toll-like receptor 1-Toll-like receptor 2 protein complexGO:003535410.2TLR1, TLR2
2lipopolysaccharide receptor complexGO:004669610.1LY96, TLR4
3intrinsic component of plasma membraneGO:00312269.3LY96, TLR2, TLR4
4external side of plasma membraneGO:00098978.7IFNG, IL6, TLR2, TLR4

Biological processes related to Melioidosis according to GeneCards Suite gene sharing:

(show top 50)    (show all 58)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of toll-like receptor signaling pathwayGO:003412310.6TLR2, TLR5
2regulation of dendritic cell cytokine productionGO:000273010.5TLR2, TLR4
3I-kappaB phosphorylationGO:000725210.5TLR2, TLR4
4detection of triacyl bacterial lipopeptideGO:004249510.5TLR1, TLR2
5cellular response to triacyl bacterial lipopeptideGO:007172710.5TLR1, TLR2
6T-helper 1 type immune responseGO:004208810.4IL18, TLR4
7positive regulation of macrophage cytokine productionGO:006090710.4TLR2, TLR4
8cellular response to lipoteichoic acidGO:007122310.4TLR2, TLR4
9macrophage activationGO:004211610.4TLR1, TLR4
10detection of lipopolysaccharideGO:003249710.4LY96, TLR4
11positive regulation of interleukin-12 biosynthetic processGO:004508410.3IFNG, TLR4
12positive regulation of interleukin-6 biosynthetic processGO:004541010.3IFNG, TLR1
13positive regulation of tumor necrosis factor biosynthetic processGO:004253510.2TLR1, TLR2, TLR4
14positive regulation of interleukin-8 productionGO:003275710.2TLR2, TLR4, TLR5
15neutrophil apoptotic processGO:000178110.1IFNG, IL6
16positive regulation of NF-kappaB import into nucleusGO:004234610.1IL18, TLR2, TLR4
17negative regulation of interleukin-17 productionGO:003270010.0IFNG, TLR2, TLR4
18type 2 immune responseGO:004209210.0IL10, IL18
19positive regulation of interleukin-12 productionGO:00327359.9IFNG, TLR2, TLR4
20positive regulation of chemokine productionGO:00327229.9IL6, TLR2, TLR4
21extrinsic apoptotic signaling pathwayGO:00971919.8IFNG, LY96, TLR4
22regulation of cytokine secretionGO:00507079.8TLR1, TLR10, TLR4, TLR5
23positive regulation of interleukin-6 productionGO:00327559.7IL6, TLR2, TLR4
24response to peptidoglycanGO:00324949.7IL6, IRAK3, TLR2
25response to bacteriumGO:00096179.6IL6, TLR2, TLR4
26lipopolysaccharide-mediated signaling pathwayGO:00316639.6IL18, LY96, TLR2, TLR4
27positive regulation of inflammatory responseGO:00507299.6IL18, TLR10, TLR2, TLR4
28negative regulation of interleukin-12 productionGO:00326959.5IL10, IRAK3, TLR2
29positive regulation of MHC class II biosynthetic processGO:00453489.5IFNG, IL10, TLR4
30negative regulation of interleukin-6 productionGO:00327159.4IL10, IRAK3, TLR4
31negative regulation of tumor necrosis factor productionGO:00327209.4IL10, IRAK3, TLR4
32negative regulation of growth of symbiont in hostGO:00441309.4IFNG, IL10, TLR2
33positive regulation of tumor necrosis factor productionGO:00327609.3IFNG, LY96, TLR2, TLR4
34toll-like receptor 2 signaling pathwayGO:00341349.3LY96, TLR1, TLR2, TLR4
35toll-like receptor 4 signaling pathwayGO:00341429.3LY96, TLR1, TLR2, TLR4
36toll-like receptor TLR1:TLR2 signaling pathwayGO:00381239.3LY96, TLR1, TLR2, TLR4
37toll-like receptor TLR6:TLR2 signaling pathwayGO:00381249.3LY96, TLR1, TLR2, TLR4
38positive regulation of NF-kappaB transcription factor activityGO:00510929.2IL6, IRAK3, TLR2, TLR4
39defense response to protozoanGO:00428329.1IFNG, IL10, IL6
40defense response to bacteriumGO:00427428.9IFNG, IL10, TLR4, TLR5
41positive regulation of nitric oxide biosynthetic processGO:00454298.8IFNG, IL6, TLR2, TLR4, TLR5
42toll-like receptor signaling pathwayGO:00022248.6LY96, TLR1, TLR10, TLR2, TLR4, TLR5
43positive regulation of gene expressionGO:00106288.4IFNG, IL18, IL6, TLR2, TLR4
44signal transductionGO:00071658.3IRAK3, TLR1, TLR10, TLR2, TLR4, TLR5
45response to lipopolysaccharideGO:00324968.2IL10, IL6, IRAK3, LY96, TLR4
46MyD88-dependent toll-like receptor signaling pathwayGO:00027558.1IRAK3, LY96, TLR1, TLR10, TLR2, TLR4
47innate immune responseGO:00450878.1LY96, TLR1, TLR10, TLR2, TLR4, TLR5
48cellular response to lipopolysaccharideGO:00712228.0IFNG, IL10, IL18, IL6, TLR4, TLR5
49inflammatory responseGO:00069547.3IL10, IL18, IL6, LY96, TLR1, TLR10
50immune responseGO:00069557.2IFNG, IL10, IL18, IL6, TLR1, TLR10

Molecular functions related to Melioidosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1lipopolysaccharide bindingGO:00015309.9TLR2, TLR4
2lipopolysaccharide receptor activityGO:00018759.8LY96, TLR2, TLR4
3transmembrane signaling receptor activityGO:00048888.9TLR1, TLR10, TLR2, TLR4, TLR5
4cytokine activityGO:00051257.8IFNG, IL10, IL18, IL6

Sources for Melioidosis

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet