MCID: MNR008
MIFTS: 23

Menieres Disease malady

Summaries for Menieres Disease

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34MalaCards
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MalaCards: Menieres Disease is related to meniere's disease and nephrogenic diabetes insipidus. An important gene associated with Menieres Disease is COCH (cochlin), and among its related pathways are Regulation of degradation of deltaF508 CFTR in CF and Proteolysis Putative ubiquitin pathway. The compounds delta-12-pgj2 and geranylgeranylacetone have been mentioned in the context of this disorder. Related mouse phenotype hearing/vestibular/ear.

Aliases & Classifications for Menieres Disease

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11DISEASES, 46Novoseek
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Aliases & Descriptions:

menieres disease 11 46


Related Diseases for Menieres Disease

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Sources:
18GeneCards, 19GeneDecks
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Graphical network of diseases related to Menieres Disease:



Diseases related to menieres disease

Symptoms for Menieres Disease

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Drugs & Therapeutics for Menieres Disease

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Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials, 63UMLS, 42NDF-RT
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Approved drugs:

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Drug clinical trials:

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Search NIH Clinical Center for Menieres Disease

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Genetic Tests for Menieres Disease

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Anatomical Context for Menieres Disease

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Animal Models for Menieres Disease or affiliated genes

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38MGI
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MGI Mouse Phenotypes related to Menieres Disease:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053779.2COCH, OCM2, FBXO2

Publications for Menieres Disease

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53PubMed
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Articles related to Menieres Disease:

idTitleAuthorsYear
1
Hypoparathyroidism. Meniere disease. (22384759)
2012
2
Intralabyrinthine fluid dynamics: Meniere disease. (15377953)
2004
3
Absence of COCH mutations in patients with Meniere disease. (14704763)
2004

Variations for Menieres Disease

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Expression for genes affiliated with Menieres Disease

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Sources:
2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Menieres Disease

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Pathways for genes affiliated with Menieres Disease

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Sources:
51PathCards, 61Thomson Reuters, 54QIAGEN, 39NCBI BioSystems Database, 56Reactome
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Compounds for genes affiliated with Menieres Disease

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Sources:
46Novoseek, 62Tocris Bioscience, 12DrugBank, 30IUPHAR, 25HMDB, 52PharmGKB
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Compounds related to Menieres Disease according to GeneCards/GeneDecks:

(show all 32)
idCompoundScoreTop Affiliating Genes
1delta-12-pgj2469.9HSPA4, HSPA8
2geranylgeranylacetone469.9HSPA4, HSPA8
3cyclopentenone469.9HSPA4, HSPA8
4mercury469.9HSPA4, MIP
5cdcl2469.8HSPA8, HSPA4
6phenylbutyrate469.8HSPA4, HSPA8
78-oxo-dg469.8HSPA4, HSPA8
8manumycin469.8HSPA4, HSPA8
9radicicol46 62 1211.8HSPA4, HSPA8
1017-(allylamino)-17-demethoxygeldanamycin469.8HSPA8, HSPA4
11sodium arsenite469.8HSPA4, HSPA8
123-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide469.8HSPA4, HSPA8
13rotenone469.7HSPA8, HSPA4
14allergens469.7OCM2, HSPA8
15manganese superoxide469.7HSPA4, HSPA8
16hg2+309.7MIP, AQP6
17salicylic acid46 3010.7HSPA8, HSPA4
18cadmium46 2510.6HSPA4, HSPA8
194-hydroxynonenal46 2510.5HSPA8, HSPA4
20silver469.5HSPA8, HSPA4, MIP
21mannitol46 1210.5HSPA8, HSPA4, MIP
22arsenite46 2510.5MIP, HSPA4, HSPA8
23adpribose469.5HSPA4, HSPA8
24alpha tocopherol469.5HSPA4, HSPA8
25potassium46 25 1211.4MIP, HSPA4, HSPA8
26hydrogen46 2510.4MIP, HSPA4, HSPA8
27geldanamycin46 52 62 1212.4HSPA4, HSPA8
28lactate469.4HSPA8, HSPA4, MIP
29sodium46 2510.3MIP, HSPA4, HSPA8
30glutamate468.9HSPA8, HSPA4, OCM2, MIP
31h2o2468.8HSPA8, HSPA4, MIP
32glycerol46 25 1210.7MIP, AQP6, HSPA4, HSPA8

GO Terms for genes affiliated with Menieres Disease

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17Gene Ontology
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Biological processes related to Menieres Disease according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1response to unfolded proteinGO:0069869.5HSPA4, HSPA8
2water transportGO:0068339.0MIP, AQP6

Molecular functions related to Menieres Disease according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1water channel activityGO:0152509.3MIP, AQP6

Products for genes affiliated with Menieres Disease

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Menieres Disease

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet