MCID: MNR008
MIFTS: 23

Menieres Disease malady

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Summaries for Menieres Disease

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33MalaCards
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MalaCards: Menieres Disease is related to meniere's disease and nephrogenic diabetes insipidus. An important gene associated with Menieres Disease is COCH (cochlin), and among its related pathways are Regulation of degradation of deltaF508 CFTR in CF and Proteolysis Putative ubiquitin pathway. The compounds delta-12-pgj2 and geranylgeranylacetone have been mentioned in the context of this disorder. Related mouse phenotype hearing/vestibular/ear.

Aliases & Classifications for Menieres Disease

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10DISEASES, 45Novoseek
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Aliases & Descriptions:

menieres disease 10 45


Related Diseases for Menieres Disease

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17GeneCards, 18GeneDecks
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Graphical network of diseases related to Menieres Disease:



Diseases related to menieres disease

Symptoms for Menieres Disease

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Drugs & Therapeutics for Menieres Disease

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42NIH Clinical Center, 6ClinicalTrials, 62UMLS, 41NDF-RT
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Drug clinical trials:

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Genetic Tests for Menieres Disease

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Anatomical Context for Menieres Disease

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Animal Models for Menieres Disease or affiliated genes

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37MGI
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MGI Mouse Phenotypes related to Menieres Disease:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053779.2COCH, OCM2, FBXO2

Publications for Menieres Disease

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52PubMed
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Articles related to Menieres Disease:

idTitleAuthorsYear
1
Hypoparathyroidism. Meniere disease. (22384759)
2012
2
Intralabyrinthine fluid dynamics: Meniere disease. (15377953)
2004
3
Absence of COCH mutations in patients with Meniere disease. (14704763)
2004

Variations for Menieres Disease

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Expression for genes affiliated with Menieres Disease

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2BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Menieres Disease

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Pathways for genes affiliated with Menieres Disease

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Sources:
50PathCards, 60Thomson Reuters, 53QIAGEN, 38NCBI BioSystems Database, 55Reactome
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Compounds for genes affiliated with Menieres Disease

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45Novoseek, 61Tocris Bioscience, 11DrugBank, 29IUPHAR, 24HMDB, 51PharmGKB
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Compounds related to Menieres Disease according to GeneCards/GeneDecks:

(show all 32)
idCompoundScoreTop Affiliating Genes
1delta-12-pgj2459.9HSPA4, HSPA8
2geranylgeranylacetone459.9HSPA4, HSPA8
3cyclopentenone459.9HSPA4, HSPA8
4mercury459.9HSPA4, MIP
5cdcl2459.8HSPA8, HSPA4
6phenylbutyrate459.8HSPA4, HSPA8
78-oxo-dg459.8HSPA4, HSPA8
8manumycin459.8HSPA4, HSPA8
9radicicol45 61 1111.8HSPA4, HSPA8
1017-(allylamino)-17-demethoxygeldanamycin459.8HSPA8, HSPA4
11sodium arsenite459.8HSPA4, HSPA8
123-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide459.8HSPA4, HSPA8
13rotenone459.7HSPA8, HSPA4
14allergens459.7OCM2, HSPA8
15manganese superoxide459.7HSPA4, HSPA8
16hg2+299.7MIP, AQP6
17salicylic acid45 2910.7HSPA8, HSPA4
18cadmium45 2410.6HSPA4, HSPA8
194-hydroxynonenal45 2410.5HSPA8, HSPA4
20silver459.5HSPA8, HSPA4, MIP
21mannitol45 1110.5HSPA8, HSPA4, MIP
22arsenite45 2410.5MIP, HSPA4, HSPA8
23adpribose459.5HSPA4, HSPA8
24alpha tocopherol459.5HSPA4, HSPA8
25potassium45 24 1111.4MIP, HSPA4, HSPA8
26hydrogen45 2410.4MIP, HSPA4, HSPA8
27geldanamycin45 51 61 1112.4HSPA4, HSPA8
28lactate459.4HSPA8, HSPA4, MIP
29sodium45 2410.3MIP, HSPA4, HSPA8
30glutamate458.9HSPA8, HSPA4, OCM2, MIP
31h2o2458.8HSPA8, HSPA4, MIP
32glycerol45 24 1110.7MIP, AQP6, HSPA4, HSPA8

GO Terms for genes affiliated with Menieres Disease

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16Gene Ontology
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Biological processes related to Menieres Disease according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1response to unfolded proteinGO:0069869.5HSPA4, HSPA8
2water transportGO:0068339.0MIP, AQP6

Molecular functions related to Menieres Disease according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1water channel activityGO:0152509.3MIP, AQP6

Products for genes affiliated with Menieres Disease

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Menieres Disease

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4CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
59SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet