MCID: MNN006
MIFTS: 39

Meninges Hemangiopericytoma

Categories: Cancer diseases, Neuronal diseases

Aliases & Classifications for Meninges Hemangiopericytoma

MalaCards integrated aliases for Meninges Hemangiopericytoma:

Name: Meninges Hemangiopericytoma 12 14
Hemangiopericytoma of Meninges 12 69
Meningeal Hemangiopericytoma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:4957
NCIt 46 C4660
SNOMED-CT 64 277522009
UMLS 69 C0349622

Summaries for Meninges Hemangiopericytoma

MalaCards based summary : Meninges Hemangiopericytoma, also known as hemangiopericytoma of meninges, is related to hemangiopericytoma, malignant and mesenchymal chondrosarcoma. An important gene associated with Meninges Hemangiopericytoma is STAT6 (Signal Transducer And Activator Of Transcription 6), and among its related pathways/superpathways are PI3K-Akt signaling pathway and MAPK signaling pathway. Affiliated tissues include bone, liver and adrenal gland, and related phenotypes are cellular and growth/size/body region

Related Diseases for Meninges Hemangiopericytoma

Diseases related to Meninges Hemangiopericytoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 87)
# Related Disease Score Top Affiliating Genes
1 hemangiopericytoma, malignant 30.7 HBA1 IGF2 NAB2 STAT6 VIM
2 mesenchymal chondrosarcoma 30.4 HEY1 NCOA2 VIM
3 meningioma, familial 29.0 CD34 EPB41L3 GFAP IGF2 TERT VIM
4 meningitis 10.6
5 slipped capital femoral epiphysis 10.5 IGF1 IGFBP3
6 primitive neuroectodermal tumor of the cervix uteri 10.5 GFAP VIM
7 cutaneous leiomyosarcoma 10.5 GFAP VIM
8 parachordoma 10.4 GFAP VIM
9 adenoid squamous cell carcinoma 10.4 HBA1 VIM
10 acid-labile subunit deficiency 10.4 IGF1 IGF2 IGFBP3
11 rhabdoid meningioma 10.4 GFAP VIM
12 laron syndrome 10.4 IGF1 IGF2 IGFBP3
13 hypoglycemic coma 10.4 IGF2 INS
14 silver-russell syndrome 10.3 IGF1 IGF2 IGFBP3
15 spindle cell rhabdomyosarcoma 10.3 GFAP NCOA2
16 angiomatous meningioma 10.3 GFAP HBA1 PLAUR
17 type 1 diabetes mellitus 2 10.3 IGF2 INS
18 secondary adrenal insufficiency 10.3 IGF1 IGFBP3 INS
19 primary hepatic neuroendocrine carcinoma 10.3 CHGA VIM
20 pineal hyperplasia, insulin-resistant diabetes mellitus, and somatic abnormalities 10.3 IGF1 IGFBP3 INS
21 rubeosis iridis 10.3 IGF1 IGF2 INS
22 pituitary adenoma 1, multiple types 10.3 IGF1 IGFBP3
23 endocrine pancreas disease 10.3 IGF1 IGF2 INS
24 hyperpituitarism 10.3 IGF1 IGFBP3 INS
25 pancreas disease 10.3 IGF1 IGF2 INS
26 cellular ependymoma 10.2 CHGA GFAP
27 syringocystadenoma papilliferum 10.2 GFAP VIM
28 hypopituitarism 10.2 IGF1 IGFBP3 INS
29 chordoid meningioma 10.2 CHGA GFAP VIM
30 clear cell meningioma 10.2 CHGA GFAP VIM
31 glucose metabolism disease 10.2 HBA1 IGF1 INS
32 fetal macrosomia 10.1 IGF1 IGF2 IGFBP3 INS
33 male reproductive organ cancer 10.1 CHGA IGF1 IGFBP3
34 intraventricular meningioma 10.1 F8 GFAP TERT
35 glomangiomyoma 10.1 CD34 VIM
36 acromegaly 10.1 IGF1 IGF2 IGFBP3 INS
37 insulin-like growth factor i 10.1 IGF1 IGF2 IGFBP3 INS
38 pineal region choriocarcinoma 10.1 CD34 IGF1
39 sternum cancer 10.1 CD34 VIM
40 ovary sarcoma 10.1 CD34 HBA1
41 hyperinsulinemic hypoglycemia, familial, 2 10.1 CHGA IGF2 INS
42 ovarian angiosarcoma 10.1 CD34 HBA1
43 small intestine leiomyosarcoma 10.1 CD34 IGF2
44 intravascular fasciitis 10.1 CD34 HBA1
45 small intestinal sarcoma 10.1 CD34 IGF2
46 malignant pineal area germ cell neoplasm 10.1 CD34 IGF1
47 thyroid angiosarcoma 10.1 CD34 HBA1
48 hypoglycemia 10.1
49 islet cell tumor 10.1 CHGA IGF2 INS
50 hyperinsulinism 10.1 IGF1 IGFBP3 INS

Graphical network of the top 20 diseases related to Meninges Hemangiopericytoma:



Diseases related to Meninges Hemangiopericytoma

Symptoms & Phenotypes for Meninges Hemangiopericytoma

MGI Mouse Phenotypes related to Meninges Hemangiopericytoma:

43 (show all 16)
# Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 10.44 HEY1 IGF1 INS IGF2 CSF1R CACNA1A
2 growth/size/body region MP:0005378 10.39 HEY1 IGFBP3 IGF1 INS IGF2 CSF1R
3 homeostasis/metabolism MP:0005376 10.38 IGFBP3 IGF1 INS IGF2 CSF1R CACNA1A
4 behavior/neurological MP:0005386 10.37 IGF2 IGFBP3 GFAP CSF1R CACNA1A EPB41L3
5 mortality/aging MP:0010768 10.28 IGF2 HEY1 IGF1 INS GFAP CSF1R
6 immune system MP:0005387 10.27 IGF2 IGF1 GFAP CSF1R CACNA1A CD34
7 endocrine/exocrine gland MP:0005379 10.26 IGF2 IGFBP3 IGF1 CSF1R CACNA1A EPB41L3
8 cardiovascular system MP:0005385 10.25 GFAP HEY1 IGF2 IGFBP3 IGF1 CHGA
9 hematopoietic system MP:0005397 10.24 IGF2 IGF1 CSF1R CACNA1A CD34 F8
10 integument MP:0010771 10.13 IGF2 IGFBP3 IGF1 CSF1R CACNA1A CD34
11 nervous system MP:0003631 10.13 IGF2 HEY1 IGF1 GFAP CSF1R CACNA1A
12 muscle MP:0005369 10.07 HEY1 IGFBP3 IGF1 INS IGF2 CACNA1A
13 normal MP:0002873 9.91 HEY1 IGF1 GFAP CSF1R CACNA1A EPB41L3
14 reproductive system MP:0005389 9.77 IGF1 INS IGF2 CSF1R CACNA1A EPB41L3
15 renal/urinary system MP:0005367 9.7 IGF2 IGFBP3 IGF1 CHGA INS PLAUR
16 respiratory system MP:0005388 9.28 IGF2 IGFBP3 IGF1 CACNA1A NAB2 STAT6

Drugs & Therapeutics for Meninges Hemangiopericytoma

Search Clinical Trials , NIH Clinical Center for Meninges Hemangiopericytoma

Genetic Tests for Meninges Hemangiopericytoma

Anatomical Context for Meninges Hemangiopericytoma

MalaCards organs/tissues related to Meninges Hemangiopericytoma:

38
Bone, Liver, Adrenal Gland, Lung, Heart

Publications for Meninges Hemangiopericytoma

Articles related to Meninges Hemangiopericytoma:

(show all 49)
# Title Authors Year
1
Liver metastasis of meningeal hemangiopericytoma: a study of 5 cases. ( 27044772 )
2016
2
Gastric metastasis from malignant meningeal hemangiopericytoma. ( 27801496 )
2016
3
NAB2-STAT6 Gene Fusion in Meningeal Hemangiopericytoma and Solitary Fibrous Tumor. ( 26883114 )
2016
4
Meningeal Hemangiopericytoma in 33-Year-Old Female; a Case Report. ( 27799979 )
2016
5
Intracranial meningeal hemangiopericytoma: Recurrences at the initial and distant intracranial sites and extraneural metastases to multiple organs. ( 26171177 )
2015
6
Liver metastases from meningeal hemangiopericytoma. ( 25913235 )
2015
7
Living-Donor Liver Transplantation for Hepatic Metastasis FromA Meningeal Hemangiopericytoma: A Case Report. ( 26361698 )
2015
8
Meningeal hemangiopericytoma only diagnosed at the time of late bone metastasis. ( 24934329 )
2014
9
Are meningeal hemangiopericytoma and mesenchymal chondrosarcoma the same?: a study of HEY1-NCOA2 fusion. ( 24124145 )
2013
10
Optic nerve meningeal hemangiopericytoma: a clinicopathologic case report. ( 23294915 )
2013
11
Metastasis of intracranial meningeal hemangiopericytoma to thoracic spine 17A years after surgical excision: a case report. ( 23943153 )
2013
12
The role of postoperative radiation therapy in the treatment of meningeal hemangiopericytoma-experience from the SEER database. ( 22867893 )
2013
13
Meningeal hemangiopericytoma and solitary fibrous tumors carry the NAB2-STAT6 fusion and can be diagnosed by nuclear expression of STAT6 protein. ( 23575898 )
2013
14
MRS study of meningeal hemangiopericytoma and edema: a comparison with meningothelial meningioma. ( 22824994 )
2012
15
Intracranial meningeal hemangiopericytoma: 10A years experience of a tertiary care Institute. ( 22790838 )
2012
16
Recurrent meningeal hemangiopericytoma with multiple metastasis and hypoglycemia: a case report. ( 23024657 )
2012
17
Meningeal Hemangiopericytoma with Intracranial Metastases in an HIV-Positive Male: Case Report and Review of the Literature. ( 22666206 )
2012
18
Intracranial meningeal hemangiopericytoma metastatic to the scapula. ( 22229602 )
2012
19
Phase II study of subcutaneous octreotide in adults with recurrent or progressive meningioma and meningeal hemangiopericytoma. ( 21558077 )
2011
20
The status of MGMT protein expression is a prognostic factor for meningeal hemangiopericytoma: a clinicopathologic and immunohistochemical study of 12 cases at a single institution. ( 21667225 )
2011
21
Response to trabectedin treatment in a highly pretreated patient with an advanced meningeal hemangiopericytoma. ( 20622667 )
2010
22
Meningeal hemangiopericytomas and hemangiopericytoma/solitary fibrous tumors of extracranial soft tissues: a comparison. ( 20165866 )
2010
23
Multiple metastatic progression of meningeal hemangiopericytoma initially diagnosed as atypical meningioma with temporal bone invasion. ( 19201308 )
2009
24
Retinoblastoma (Rb) tumor-suppressor pathway alterations in meningeal hemangiopericytomas: High E2F transcription factor 1 expression and loss of Rb expression: study by double immunofluorescence staining and laser-scanning confocal microscopy. ( 18459177 )
2008
25
Meningeal hemangiopericytoma manifesting as massive intracranial hemorrhage--two case reports. ( 16498220 )
2006
26
Bone metastasis of intracranial meningeal hemangiopericytoma. ( 15990973 )
2005
27
Anaplastic meningioma versus meningeal hemangiopericytoma: immunohistochemical and genetic markers. ( 15668900 )
2004
28
Meningeal hemangiopericytoma with delayed multiple distant metastases. ( 15648288 )
2004
29
Intracranial meningeal hemangiopericytoma: the role of radiotherapy: report of 29 cases and review of the literature. ( 15042684 )
2004
30
Meningeal hemangiopericytoma metastatic to the adrenal gland with multiple metastases to bones and lungs: a case report. ( 15143990 )
2004
31
[Multiple extracranial metastases from a meningeal hemangiopericytoma and severe hypoglycemia: a case report]. ( 15227844 )
2004
32
Fine needle aspiration cytology of hepatic metastasis from a meningeal hemangiopericytoma. A case report. ( 12685202 )
2003
33
Fetal meningeal hemangiopericytoma. Case report. ( 12450048 )
2002
34
Prostaglandin D synthase (beta-trace) in meningeal hemangiopericytoma. ( 11266526 )
2001
35
Four cases of meningeal hemangiopericytoma treated with surgery and radiotherapy. ( 11773263 )
2001
36
Meningeal hemangiopericytoma: a retrospective study of 21 patients with special review of postoperative external radiotherapy. ( 11322435 )
2001
37
Tc-99m MDP and Tl-201 scintigraphy in a case of metastatic meningeal hemangiopericytoma. ( 11711721 )
2001
38
[Contribution of immunohistochemistry and electron microscopy for the diagnosis of meningeal hemangiopericytomas. 15 case reports]. ( 11084416 )
2000
39
Pancreatic head mass from metastatic meningeal hemangiopericytoma. ( 18521297 )
2000
40
Meningeal hemangiopericytoma in childhood. ( 11003400 )
2000
41
Hepatic and pulmonary metastases from a meningeal hemangiopericytoma and severe hypoglycemia due to abnormal secretion of insulin-like growth factor: a case report. ( 10326704 )
1999
42
Radiotherapy of bone metastases of a spinal meningeal hemangiopericytoma. ( 9581183 )
1998
43
Metastatic meningeal hemangiopericytoma of thoracic spine. ( 9822848 )
1998
44
Management of recurrent meningeal hemangiopericytoma. ( 9587125 )
1998
45
The immunophenotypic spectrum of meningeal hemangiopericytoma: a comparison with fibrous meningioma and solitary fibrous tumor of meninges. ( 9351573 )
1997
46
Meningeal hemangiopericytoma metastatic to the heart. ( 8776772 )
1996
47
Insulin-like growth factor II expression in primary meningeal hemangiopericytoma and its metastasis to the liver accompanied by hypoglycemia. ( 8760024 )
1996
48
The contribution of cytogenetics to the histogenesis of meningeal hemangiopericytoma. ( 8858518 )
1996
49
Soft-tissue and meningeal hemangiopericytomas: an immunohistochemical and ultrastructural study. ( 2318483 )
1990

Variations for Meninges Hemangiopericytoma

Expression for Meninges Hemangiopericytoma

Search GEO for disease gene expression data for Meninges Hemangiopericytoma.

Pathways for Meninges Hemangiopericytoma

GO Terms for Meninges Hemangiopericytoma

Cellular components related to Meninges Hemangiopericytoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.91 CD34 CHGA F8 HBA1 IGF1 IGF2
2 endoplasmic reticulum lumen GO:0005788 9.62 F8 IGFBP3 INS PLAUR
3 platelet alpha granule lumen GO:0031093 9.33 F8 IGF1 IGF2
4 insulin-like growth factor ternary complex GO:0042567 8.96 IGF1 IGFBP3
5 insulin-like growth factor binding protein complex GO:0016942 8.62 IGF1 IGFBP3

Biological processes related to Meninges Hemangiopericytoma according to GeneCards Suite gene sharing:

(show all 12)
# Name GO ID Score Top Affiliating Genes
1 cellular protein metabolic process GO:0044267 9.71 IGF1 IGF2 IGFBP3 INS
2 positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 9.65 IGF1 IGF2 INS
3 movement of cell or subcellular component GO:0006928 9.63 IGF1 PLAUR VIM
4 positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 9.51 IGF1 IGFBP3
5 positive regulation of insulin receptor signaling pathway GO:0046628 9.49 IGF2 INS
6 negative regulation of blood vessel diameter GO:0097756 9.43 CHGA INS
7 positive regulation of glucose import GO:0046326 9.43 IGF1 INS TERT
8 Bergmann glial cell differentiation GO:0060020 9.37 GFAP VIM
9 positive regulation of mitotic nuclear division GO:0045840 9.33 IGF1 IGF2 INS
10 intermediate filament-based process GO:0045103 9.32 GFAP VIM
11 positive regulation of MAPK cascade GO:0043410 9.26 IGF1 IGF2 IGFBP3 INS
12 positive regulation of glycogen biosynthetic process GO:0045725 8.8 IGF1 IGF2 INS

Molecular functions related to Meninges Hemangiopericytoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 insulin receptor binding GO:0005158 9.13 IGF1 IGF2 INS
2 insulin-like growth factor receptor binding GO:0005159 8.8 IGF1 IGF2 INS
3 protein binding GO:0005515 10.11 CACNA1A CSF1R EPB41L3 F8 GFAP HBA1

Sources for Meninges Hemangiopericytoma

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