MCID: MNN011
MIFTS: 25

Meninges Sarcoma malady

Categories: Cancer diseases, Neuronal diseases, Immune diseases

Aliases & Classifications for Meninges Sarcoma

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Aliases & Descriptions for Meninges Sarcoma:

Name: Meninges Sarcoma 11 13
Leptomeningeal Sarcoma 68
Meningothelial Sarcoma 68
 
Sarcoma of Meninges 11
Meningeal Sarcoma 11

Classifications:



External Ids:

Disease Ontology11 DOID:7614
SNOMED-CT62 277996009, 78303004
NCIt45 C4073

Summaries for Meninges Sarcoma

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MalaCards based summary: Meninges Sarcoma, also known as leptomeningeal sarcoma, is related to malignant giant cell tumor of the tendon sheath and bone remodeling disease. An important gene associated with Meninges Sarcoma is CSF1R (Colony Stimulating Factor 1 Receptor), and among its related pathways are C-MYB transcription factor network and Dendritic Cells Developmental Lineage Pathway. Related mouse phenotypes are craniofacial and limbs/digits/tail.

Related Diseases for Meninges Sarcoma

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Diseases related to Meninges Sarcoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 82)
idRelated DiseaseScoreTop Affiliating Genes
1malignant giant cell tumor of the tendon sheath10.4CSF1R, TP53
2bone remodeling disease10.4MB, TP53
3bile duct disease10.4MB, TP53
4pulmonary plasma cell granuloma10.4MB, TP53
5goiter, multinodular 1, with or without sertoli-leydig cell tumors10.3MB, TP53
6vibratory urticaria10.3MB, TP53
7pediatric fibrosarcoma10.3CD34, MB
8akinetic mutism10.3CD34, MB
9adult central nervous system primitive neuroectodermal neoplasm10.3MB, TP53
10vulvar sebaceous carcinoma10.3MB, TP53
11borna disease10.3CD34, TP53
12esophagus leiomyoma10.3CD34, MB
13hypersensitivity reaction type ii disease10.3IGF2, TP53
14bone benign neoplasm10.3CD34, MB
15neuroma10.3CSF1R, TP53
16hemangioblastoma10.3CD34, MB
17omphalocele10.2CD34, MB
18cell type benign neoplasm10.2CD34, TP53
19cartilage cancer10.2CD34, TP53
20mucinous adenocarcinoma10.2IGF2, TP53
21hypoglossal nerve neoplasm10.2CD34, TP53
22frontal sinus squamous cell carcinoma10.2CD34, MB
23pancreatic cancer10.2IGF2, TP53
24peritoneal benign neoplasm10.2CD34, TP53
25breast adenoma10.2CD34, TP53
26breast capillary hemangioma10.2CD34, IGF2
27pulmonary immaturity10.2IGF2, MB
28pediatric ependymoma10.2CD34, TP53
29anus leiomyosarcoma10.2CD34, MB
30fallopian tube adenosarcoma10.2MB, TP53
31glioma susceptibility 110.2IGF2, TP53
32clear cell sarcoma10.2MB, TP53
33liver rhabdomyosarcoma10.2IGF2, MB
34chikungunya10.1CD34, TP53
35vestibular gland benign neoplasm10.1CD34, TP53
36esophagitis10.1CD34, TP53
37malignant mediastinal neurogenic neoplasm10.1CD34, CREB3L2
38lateral medullary syndrome10.1CD34, CREB3L2
39bile duct mucoepidermoid carcinoma10.1CD34, CREB3L2
40kidney lipoma10.1CD34, CREB3L2
41vulvar liposarcoma10.1CD34, CREB3L2
42periodontal disease10.1CD34, TP53
43malignant fibrous histiocytoma of bone10.1CD34, CREB3L2
44lumbosacral lipoma10.1CD34, CREB3L2
45male reproductive organ benign neoplasm10.1CD34, TP53
46cellular myxoid liposarcoma10.1CD34, CREB3L2
47spinal cord primitive neuroectodermal neoplasm10.1IGF2, TP53
48gallbladder leiomyosarcoma10.0CD34, CREB3L2
49neutrophil immunodeficiency syndrome10.0CD34, TP53
50epidural neoplasm10.0CD34, CREB3L2

Graphical network of the top 20 diseases related to Meninges Sarcoma:



Diseases related to meninges sarcoma

Symptoms & Phenotypes for Meninges Sarcoma

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MGI Mouse Phenotypes related to Meninges Sarcoma according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053829.2CREB3L2, CSF1R, IGF2, TP53
2MP:00053718.5CREB3L2, CSF1R, IGF2, TP53

Drugs & Therapeutics for Meninges Sarcoma

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Meninges Sarcoma

Genetic Tests for Meninges Sarcoma

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Anatomical Context for Meninges Sarcoma

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Publications for Meninges Sarcoma

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Articles related to Meninges Sarcoma:

idTitleAuthorsYear
1
Long-term survival in gliosarcoma with radiation-induced meningeal sarcomas: Case report and molecular features. (26458625)
2015
2
Primary C1-2, intradural, extramedullary meningeal sarcoma with glial fibrillary acidic protein-immunoreactive components: a spinal gliosarcoma? Case report and review of the literature. (12450287)
2002
3
Meningeal sarcoma with rhabdomyoblastic differentiation: case report. (1584397)
1992

Variations for Meninges Sarcoma

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Expression for genes affiliated with Meninges Sarcoma

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Search GEO for disease gene expression data for Meninges Sarcoma.

Pathways for genes affiliated with Meninges Sarcoma

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Pathways related to Meninges Sarcoma according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.6CD34, CSF1R
29.6CD34, CSF1R
39.0CREB3L2, CSF1R, TP53

GO Terms for genes affiliated with Meninges Sarcoma

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Biological processes related to Meninges Sarcoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1hemopoiesisGO:003009710.0CD34, CSF1R
2positive regulation of protein serine/threonine kinase activityGO:00719029.6CSF1R, IGF2
3cell proliferationGO:00082838.8CD34, CSF1R, GCG, TP53

Molecular functions related to Meninges Sarcoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1protein phosphatase bindingGO:00199039.6CSF1R, TP53

Sources for Meninges Sarcoma

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet