MCID: MNN011
MIFTS: 25

Meninges Sarcoma malady

Categories: Cancer diseases, Neuronal diseases

Aliases & Classifications for Meninges Sarcoma

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Aliases & Descriptions for Meninges Sarcoma:

Name: Meninges Sarcoma 11 13
Leptomeningeal Sarcoma 68
Meningothelial Sarcoma 68
 
Sarcoma of Meninges 11
Meningeal Sarcoma 11

Classifications:



External Ids:

Disease Ontology11 DOID:7614
SNOMED-CT62 277996009, 78303004
NCIt45 C4073

Summaries for Meninges Sarcoma

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MalaCards based summary: Meninges Sarcoma, also known as leptomeningeal sarcoma, is related to verruciform xanthoma of skin and bone deterioration disease. An important gene associated with Meninges Sarcoma is MB (Myoglobin), and among its related pathways are C-MYB transcription factor network and Dendritic Cells Developmental Lineage Pathway. Related mouse phenotypes are craniofacial and limbs/digits/tail.

Related Diseases for Meninges Sarcoma

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Diseases related to Meninges Sarcoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 62)
idRelated DiseaseScoreTop Affiliating Genes
1verruciform xanthoma of skin10.2MB, TP53
2bone deterioration disease10.2MB, TP53
3rhabdomyosarcoma, embryonal, 210.2MB, TP53
4malignant giant cell tumor10.2CSF1R, TP53
5intraorbital meningioma10.2MB, TP53
6arthus reaction10.2MB, TP53
7microsporidiosis10.2CD34, MB
8childhood medulloblastoma10.2MB, TP53
9arteriosclerosis obliterans10.2CD34, TP53
10blood group incompatibility10.1IGF2, TP53
11lice infestation10.1CD34, MB
12male reproductive organ benign neoplasm10.1CD34, TP53
13central nervous system primitive neuroectodermal neoplasm10.1CD34, TP53
14ossifying fibromyxoid tumor10.1CD34, TP53
15neurofibroma10.1CD34, MB
16uterine benign neoplasm10.1CD34, MB
17pancreatic cancer10.1IGF2, TP53
18conventional leiomyosarcoma10.1CD34, MB
19vascular myelopathy10.1CD34, TP53
20submucosal invasive colon adenocarcinoma10.1IGF2, TP53
21hyperpituitarism10.1CD34, MB
22pharynx cancer10.1CD34, TP53
23pulmonary immaturity10.1MB, TP53
24intraneural perineurioma10.1CD34, CREB3L2
25cerebral arterial disease10.1CD34, CREB3L2
26mucoepidermoid esophageal carcinoma10.1CD34, CREB3L2
27breast squamous cell carcinoma10.1CD34, TP53
28sick building syndrome10.1CD34, CREB3L2
29hormone producing pituitary cancer10.1CD34, CREB3L2
30pleural lipoma10.1CD34, CREB3L2
31fibrosarcoma10.1CD34, CREB3L2
32childhood immature teratoma of ovary10.1CD34, CREB3L2
33glioma susceptibility 110.0IGF2, TP53
34liposarcoma of the ovary10.0CD34, CREB3L2
35mediastinum rhabdomyosarcoma10.0IGF2, MB
36choriocarcinoma of ovary10.0CD34, MB, TP53
37prostate rhabdomyosarcoma10.0IGF2, MB, TP53
38palmoplantar keratosis10.0CD34, MB, TP53
39adenosarcoma10.0IGF2, MB, TP53
40malignant pleural solitary fibrous tumor10.0CD34, MB, TP53
41neutrophil immunodeficiency syndrome10.0CD34, TP53
42anterior foramen magnum meningioma10.0CD34, TP53
43maturity-onset diabetes of the young, type 1310.0GCG, IGF2
44endodermal sinus tumor10.0CREB3L2, MB, TP53
45gerstmann syndrome10.0CD34, CSF1R, IGF2
46brain stem angioblastoma10.0CD34, IGF2, TP53
47intracranial liposarcoma9.9CD34, CREB3L2, MB
48proctitis9.9CD34, IGF2, TP53
49orofaciodigital syndrome iv9.9CD34, IGF2, TP53
50endocrine organ benign neoplasm9.9CD34, TP53

Graphical network of the top 20 diseases related to Meninges Sarcoma:



Diseases related to meninges sarcoma

Symptoms & Phenotypes for Meninges Sarcoma

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MGI Mouse Phenotypes related to Meninges Sarcoma according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053829.2CREB3L2, CSF1R, IGF2, TP53
2MP:00053718.5CREB3L2, CSF1R, IGF2, TP53

Drugs & Therapeutics for Meninges Sarcoma

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Meninges Sarcoma

Genetic Tests for Meninges Sarcoma

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Anatomical Context for Meninges Sarcoma

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Publications for Meninges Sarcoma

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Articles related to Meninges Sarcoma:

idTitleAuthorsYear
1
Long-term survival in gliosarcoma with radiation-induced meningeal sarcomas: Case report and molecular features. (26458625)
2015
2
Primary C1-2, intradural, extramedullary meningeal sarcoma with glial fibrillary acidic protein-immunoreactive components: a spinal gliosarcoma? Case report and review of the literature. (12450287)
2002
3
Meningeal sarcoma with rhabdomyoblastic differentiation: case report. (1584397)
1992

Variations for Meninges Sarcoma

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Expression for genes affiliated with Meninges Sarcoma

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Search GEO for disease gene expression data for Meninges Sarcoma.

Pathways for genes affiliated with Meninges Sarcoma

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Pathways related to Meninges Sarcoma according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.5CD34, CSF1R
29.5CD34, CSF1R
39.0CREB3L2, CSF1R, TP53
49.0CREB3L2, CSF1R, TP53

GO Terms for genes affiliated with Meninges Sarcoma

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Biological processes related to Meninges Sarcoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1hemopoiesisGO:003009710.3CD34, CSF1R
2positive regulation of protein serine/threonine kinase activityGO:00719029.5CSF1R, IGF2
3cell proliferationGO:00082839.0CD34, CSF1R, GCG, TP53
4multicellular organism developmentGO:00072758.9CREB3L2, CSF1R, IGF2, TP53

Molecular functions related to Meninges Sarcoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1protein phosphatase bindingGO:00199039.6CSF1R, TP53

Sources for Meninges Sarcoma

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet