MCID: MNN011
MIFTS: 24

Meninges Sarcoma

Categories: Cancer diseases, Neuronal diseases

Aliases & Classifications for Meninges Sarcoma

MalaCards integrated aliases for Meninges Sarcoma:

Name: Meninges Sarcoma 12 14
Leptomeningeal Sarcoma 69
Meningothelial Sarcoma 69
Sarcoma of Meninges 12
Meningeal Sarcoma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:7614
NCIt 47 C4073
SNOMED-CT 64 277996009 78303004
UMLS 69 C0302327

Summaries for Meninges Sarcoma

MalaCards based summary : Meninges Sarcoma, also known as leptomeningeal sarcoma, is related to malignant giant cell tumor and embryonal extrahepatic bile duct rhabdomyosarcoma. An important gene associated with Meninges Sarcoma is CSF1R (Colony Stimulating Factor 1 Receptor), and among its related pathways/superpathways are C-MYB transcription factor network and MAPK Signaling: Mitogen Stimulation Pathway. Related phenotypes are craniofacial and limbs/digits/tail

Related Diseases for Meninges Sarcoma

Diseases related to Meninges Sarcoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 70)
id Related Disease Score Top Affiliating Genes
1 malignant giant cell tumor 10.4 CSF1R TP53
2 embryonal extrahepatic bile duct rhabdomyosarcoma 10.4 MB TP53
3 goiter, multinodular 1, with or without sertoli-leydig cell tumors 10.4 MB TP53
4 hypersensitivity reaction type iii disease 10.4 MB TP53
5 biliary dyskinesia 10.4 MB TP53
6 encephalitozoonosis 10.4 CD34 MB
7 multiple mucosal neuroma 10.3 CD34 TP53
8 rh isoimmunization 10.3 IGF2 TP53
9 melanotic medulloblastoma 10.3 MB TP53
10 plantar fasciitis 10.3 CD34 MB
11 breast epithelioid hemangioma 10.3 IGF2 TP53
12 organ system benign neoplasm 10.3 CD34 TP53
13 cartilage cancer 10.3 CD34 TP53
14 lung clear cell-sugar-tumor 10.3 MB TP53
15 epithelioid cell synovial sarcoma 10.3 CD34 MB
16 bone benign neoplasm 10.3 CD34 MB
17 cataract 24, anterior polar 10.3 IGF2 TP53
18 bone development disease 10.3 IGF2 TP53
19 hilar cholangiocellular carcinoma 10.3 CD34 MB
20 ossifying fibromyxoid tumor 10.3 CD34 TP53
21 c-p angle neurinoma 10.3 CD34 TP53
22 peritoneal benign neoplasm 10.2 CD34 TP53
23 hyperpituitarism 10.2 CD34 MB
24 colon signet ring adenocarcinoma 10.2 IGF2 TP53
25 toxic pneumonitis 10.2 CD34 TP53
26 cerebrum cancer 10.2 IGF2 MB
27 endophthalmitis 10.2 CD34 CREB3L2
28 brain stem infarction 10.2 CD34 CREB3L2
29 sick building syndrome 10.2 CD34 CREB3L2
30 cutaneous mucoepidermoid carcinoma 10.2 CD34 CREB3L2
31 prostate embryonal rhabdomyosarcoma 10.2 IGF2 MB
32 cutaneous liposarcoma 10.1 CD34 CREB3L2
33 spindle cell sarcoma 10.1 MB TP53
34 fibrosarcoma of bone 10.1 CD34 CREB3L2
35 vestibular gland benign neoplasm 10.1 CD34 TP53
36 central nervous system rhabdomyosarcoma 10.1 IGF2 MB
37 mucinous intrahepatic cholangiocarcinoma 10.1 CD34 CREB3L2
38 kidney lipoma 10.1 CD34 CREB3L2
39 basal cell carcinoma 7 10.1 IGF2 TP53
40 leydig cell tumor 10.1 CD34 CREB3L2
41 adult liposarcoma 10.1 CD34 CREB3L2
42 postmenopausal atrophic vaginitis 10.1 CD34 TP53
43 male reproductive organ benign neoplasm 10.0 CD34 TP53
44 neutrophil immunodeficiency syndrome 9.9 CD34 TP53
45 fallopian tube squamous cell carcinoma 9.9 CD34 MB TP53
46 adenosarcoma 9.9 IGF2 MB TP53
47 accessory nerve disease 9.9 CD34 MB TP53
48 prostate rhabdomyosarcoma 9.9 IGF2 MB TP53
49 pericardial tuberculosis 9.9 CD34 CSF1R IGF2
50 acral lentiginous melanoma 9.9 CD34 TP53

Graphical network of the top 20 diseases related to Meninges Sarcoma:



Diseases related to Meninges Sarcoma

Symptoms & Phenotypes for Meninges Sarcoma

MGI Mouse Phenotypes related to Meninges Sarcoma:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 craniofacial MP:0005382 9.26 CREB3L2 CSF1R IGF2 TP53
2 limbs/digits/tail MP:0005371 8.92 CSF1R IGF2 TP53 CREB3L2

Drugs & Therapeutics for Meninges Sarcoma

Search Clinical Trials , NIH Clinical Center for Meninges Sarcoma

Genetic Tests for Meninges Sarcoma

Anatomical Context for Meninges Sarcoma

Publications for Meninges Sarcoma

Articles related to Meninges Sarcoma:

id Title Authors Year
1
Long-term survival in gliosarcoma with radiation-induced meningeal sarcomas: Case report and molecular features. ( 26458625 )
2015
2
Primary C1-2, intradural, extramedullary meningeal sarcoma with glial fibrillary acidic protein-immunoreactive components: a spinal gliosarcoma? Case report and review of the literature. ( 12450287 )
2002
3
Meningeal sarcoma with rhabdomyoblastic differentiation: case report. ( 1584397 )
1992

Variations for Meninges Sarcoma

Expression for Meninges Sarcoma

Search GEO for disease gene expression data for Meninges Sarcoma.

Pathways for Meninges Sarcoma

Pathways related to Meninges Sarcoma according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1 11.05 CD34 CSF1R
2
Show member pathways
11.01 CREB3L2 CSF1R TP53
3 10.84 CD34 CSF1R

GO Terms for Meninges Sarcoma

Biological processes related to Meninges Sarcoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 multicellular organism development GO:0007275 9.46 CREB3L2 CSF1R IGF2 TP53
2 positive regulation of protein serine/threonine kinase activity GO:0071902 8.96 CSF1R IGF2
3 cell proliferation GO:0008283 8.92 CD34 CSF1R GCG TP53

Molecular functions related to Meninges Sarcoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 protein phosphatase binding GO:0019903 8.62 CSF1R TP53

Sources for Meninges Sarcoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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