MCID: MNN011
MIFTS: 25

Meninges Sarcoma malady

Categories: Cancer diseases, Neuronal diseases

Aliases & Classifications for Meninges Sarcoma

Aliases & Descriptions for Meninges Sarcoma:

Name: Meninges Sarcoma 12 14
Leptomeningeal Sarcoma 69
Meningothelial Sarcoma 69
Sarcoma of Meninges 12
Meningeal Sarcoma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:7614
NCIt 47 C4073
SNOMED-CT 64 277996009 78303004
UMLS 69 C0302327

Summaries for Meninges Sarcoma

MalaCards based summary : Meninges Sarcoma, also known as leptomeningeal sarcoma, is related to verruciform xanthoma of skin and bone deterioration disease. An important gene associated with Meninges Sarcoma is MB (Myoglobin), and among its related pathways/superpathways are PI3K-Akt signaling pathway and C-MYB transcription factor network. Related phenotypes are craniofacial and limbs/digits/tail

Related Diseases for Meninges Sarcoma

Diseases related to Meninges Sarcoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 62)
id Related Disease Score Top Affiliating Genes
1 verruciform xanthoma of skin 10.2 MB TP53
2 bone deterioration disease 10.2 MB TP53
3 rhabdomyosarcoma, embryonal, 2 10.2 MB TP53
4 malignant giant cell tumor 10.2 CSF1R TP53
5 intraorbital meningioma 10.2 MB TP53
6 arthus reaction 10.2 MB TP53
7 microsporidiosis 10.2 CD34 MB
8 childhood medulloblastoma 10.2 MB TP53
9 arteriosclerosis obliterans 10.2 CD34 TP53
10 blood group incompatibility 10.1 IGF2 TP53
11 lice infestation 10.1 CD34 MB
12 male reproductive organ benign neoplasm 10.1 CD34 TP53
13 central nervous system primitive neuroectodermal neoplasm 10.1 CD34 TP53
14 ossifying fibromyxoid tumor 10.1 CD34 TP53
15 neurofibroma 10.1 CD34 MB
16 uterine benign neoplasm 10.1 CD34 MB
17 pancreatic cancer 10.1 IGF2 TP53
18 conventional leiomyosarcoma 10.1 CD34 MB
19 vascular myelopathy 10.1 CD34 TP53
20 submucosal invasive colon adenocarcinoma 10.1 IGF2 TP53
21 hyperpituitarism 10.1 CD34 MB
22 pharynx cancer 10.1 CD34 TP53
23 pulmonary immaturity 10.1 MB TP53
24 intraneural perineurioma 10.1 CD34 CREB3L2
25 cerebral arterial disease 10.1 CD34 CREB3L2
26 mucoepidermoid esophageal carcinoma 10.1 CD34 CREB3L2
27 breast squamous cell carcinoma 10.1 CD34 TP53
28 sick building syndrome 10.1 CD34 CREB3L2
29 hormone producing pituitary cancer 10.1 CD34 CREB3L2
30 pleural lipoma 10.1 CD34 CREB3L2
31 fibrosarcoma 10.1 CD34 CREB3L2
32 childhood immature teratoma of ovary 10.1 CD34 CREB3L2
33 glioma susceptibility 1 10.0 IGF2 TP53
34 liposarcoma of the ovary 10.0 CD34 CREB3L2
35 mediastinum rhabdomyosarcoma 10.0 IGF2 MB
36 choriocarcinoma of ovary 10.0 CD34 MB TP53
37 prostate rhabdomyosarcoma 10.0 IGF2 MB TP53
38 palmoplantar keratosis 10.0 CD34 MB TP53
39 adenosarcoma 10.0 IGF2 MB TP53
40 malignant pleural solitary fibrous tumor 10.0 CD34 MB TP53
41 neutrophil immunodeficiency syndrome 10.0 CD34 TP53
42 anterior foramen magnum meningioma 10.0 CD34 TP53
43 maturity-onset diabetes of the young, type 13 10.0 GCG IGF2
44 endodermal sinus tumor 10.0 CREB3L2 MB TP53
45 gerstmann syndrome 10.0 CD34 CSF1R IGF2
46 brain stem angioblastoma 10.0 CD34 IGF2 TP53
47 intracranial liposarcoma 9.9 CD34 CREB3L2 MB
48 proctitis 9.9 CD34 IGF2 TP53
49 orofaciodigital syndrome iv 9.9 CD34 IGF2 TP53
50 endocrine organ benign neoplasm 9.9 CD34 TP53

Graphical network of the top 20 diseases related to Meninges Sarcoma:



Diseases related to Meninges Sarcoma

Symptoms & Phenotypes for Meninges Sarcoma

MGI Mouse Phenotypes related to Meninges Sarcoma:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 craniofacial MP:0005382 9.26 CREB3L2 CSF1R IGF2 TP53
2 limbs/digits/tail MP:0005371 8.92 CREB3L2 CSF1R IGF2 TP53

Drugs & Therapeutics for Meninges Sarcoma

Search Clinical Trials , NIH Clinical Center for Meninges Sarcoma

Genetic Tests for Meninges Sarcoma

Anatomical Context for Meninges Sarcoma

Publications for Meninges Sarcoma

Articles related to Meninges Sarcoma:

id Title Authors Year
1
Long-term survival in gliosarcoma with radiation-induced meningeal sarcomas: Case report and molecular features. ( 26458625 )
2015
2
Primary C1-2, intradural, extramedullary meningeal sarcoma with glial fibrillary acidic protein-immunoreactive components: a spinal gliosarcoma? Case report and review of the literature. ( 12450287 )
2002
3
Meningeal sarcoma with rhabdomyoblastic differentiation: case report. ( 1584397 )
1992

Variations for Meninges Sarcoma

Expression for Meninges Sarcoma

Search GEO for disease gene expression data for Meninges Sarcoma.

Pathways for Meninges Sarcoma

Pathways related to Meninges Sarcoma according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1 11.67 CREB3L2 CSF1R TP53
2 11.15 CD34 CSF1R
3 11.04 CD34 CSF1R
4 10.95 CREB3L2 CSF1R TP53

GO Terms for Meninges Sarcoma

Biological processes related to Meninges Sarcoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 multicellular organism development GO:0007275 9.46 CREB3L2 CSF1R IGF2 TP53
2 hemopoiesis GO:0030097 9.26 CD34 CSF1R
3 positive regulation of protein serine/threonine kinase activity GO:0071902 8.96 CSF1R IGF2
4 cell proliferation GO:0008283 8.92 CD34 CSF1R GCG TP53

Molecular functions related to Meninges Sarcoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 protein phosphatase binding GO:0019903 8.62 CSF1R TP53

Sources for Meninges Sarcoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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