MCID: MNN013
MIFTS: 71

Meningitis malady

Neuronal diseases category

Summaries for Meningitis

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Sources:
8Disease Ontology, 33MedlinePlus, 3CDC, 43NINDS, 63Wikipedia, 32MalaCards
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MedlinePlus:33 Meningitis is inflammation of the thin tissue that surrounds the brain and spinal cord, called the meninges. there are several types of meningitis. the most common is viral meningitis, which you get when a virus enters the body through the nose or mouth and travels to the brain. bacterial meningitis is rare, but can be deadly. it usually starts with bacteria that cause a cold-like infection. it can block blood vessels in the brain and lead to stroke and brain damage. it can also harm other organs. pneumococcal infections and meningococcal infections can cause bacterial meningitis. anyone can get meningitis, but it is more common in people whose bodies have trouble fighting infections. meningitis can progress rapidly. you should seek medical care quickly if you have a sudden fever a severe headache a stiff neck early treatment can help prevent serious problems, including death. vaccines can prevent some of the bacterial infections that cause meningitis. parents of adolescents and students living in college dorms should talk to a doctor about the vaccination. nih: national institute of neurological disorders and stroke

MalaCards: Meningitis is related to bacterial meningitis and aseptic meningitis. An important gene associated with Meningitis is NF2 (neurofibromin 2 (merlin)), and among its related pathways are Toll-like receptor signaling pathway and Akt Signaling. The compounds vegf and cysteine have been mentioned in the context of this disorder. Affiliated tissues include brain, spinal cord and testes, and related mouse phenotypes are immune system and mortality/aging.

Disease Ontology:8 Meningitis is a nervous system infectious disease characterized as an inflammation of the pia-arachnoid meninges. it can be caused by growth of bacteria, fungi, or parasites within the subarachnoid space or by the growth of bacteria or viruses within the meningeal or ependymal cells. meningitis is a diffuse infection caused by a variety of different agents.

CDC:3 Meningitis is a disease caused by the inflammation of the protective membranes covering the brain and spinal cord known as the meninges. The inflammation is usually caused by an infection of the fluid surrounding the brain and spinal cord.

NINDS:43 Meningitis and encephalitis are inflammatory diseases of the membranes that surround the brain and spinal cord and are caused by bacterial or viral infections. Viral meningitis is sometimes called aseptic meningitis to indicate it is not the result of bacterial infection and cannot be treated with antibiotics. Symptoms of encephalitis include sudden fever, headache, vomiting, heightened sensitivity to light, stiff neck and back, confusion and impaired judgment, drowsiness, weak muscles, a clumsy and unsteady gait, and irritability. Symptoms that might require emergency treatment include loss of consciousness, seizures, muscle weakness, or sudden severe dementia.

Wikipedia:63 Meningitis (from Ancient Greek μῆνιγξ/méniŋks, \"membrane\" and the medical suffix -itis,... more...

Aliases & Classifications for Meningitis

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Sources:
8Disease Ontology, 43NINDS, 10DISEASES, 44Novoseek, 33MedlinePlus, 60UMLS, 56SNOMED-CT, 27ICD9CM, 34MeSH, 39NCIt, 25ICD10
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Related Diseases for Meningitis

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Sources:
17GeneCards, 18GeneDecks
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Diseases in the Viral Meningitis family:

Bacterial Meningitis Chronic Meningitis
meningitis

Diseases related to Meningitis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 765)
idRelated DiseaseScoreTop Affiliating Genes
1bacterial meningitis31.7ADA, LACTB, CFP, IL1B, IL8, CXCL1
2aseptic meningitis31.6ADA, GUSB, SOD2, CCL3
3viral meningitis31.2ADA, IL6, IL8, CRP
4tuberculosis30.9LYZ, ADA, LACTB, IL1B, IL10, NF2
5encephalitis30.8IL1B, TLR2, CAT, CCL3
6pneumonia30.8LACTB, IL6, IL1B, IL8, IL10, CXCL1
7influenza30.8ADA, LACTB, MBL2, SOD2, IFNG
8meningioma30.7NF2
9leukemia30.6LYZ, ADA, LACTB, IL6, IL1B, CXCL1
10herpes simplex30.6NF2, NTF3, SOD2, TLR2
11endocarditis30.5LACTB
12melanoma30.5ADA, LACTB, MMP9, IL8, IL10, CXCL1
13otitis media30.4LACTB, IL1B, MBL2, TLR2
14measles30.4TLR2
15hepatitis30.4GUSB, SOD2, TLR2, CAT
16systemic lupus erythematosus30.4ADA, CFP, IL6, IL10, CRP, GUSB
17lupus erythematosus30.4CFP
18vasculitis30.3CXCL1, CRP, MBL2
19acquired immunodeficiency syndrome30.3IL6, IL1B
20acute leukemia30.3LACTB
21endophthalmitis30.3LACTB
22sarcoma30.3LYZ, ADA, NF2, GUSB, SOD2
23hypertension30.3MMP9, CRP
24arthritis30.3IL6, IL1B, IL8
25pericarditis30.3ADA
26encephalomyelitis30.3IL10, CXCL1, NTF3, IFNG, CCL3
27multiple sclerosis30.2MMP9, IL6, IL1B, IL10, CXCL1, MBL2
28brain edema30.2MMP9
29adenocarcinoma30.2ADA, MMP9, NF2, NTF3, GUSB, SOD2
30connective tissue disease30.2CFP, IL6, IL10
31osteomyelitis30.1LACTB, CRP, CAT
32adult-onset still's disease30.1IL6, CRP
33myeloma30.1IL6, IL1B, CCL3
34neuropathy30.1NTF3, SOD2
35meningococcal meningitis30.1CFP, MBL2
36candidiasis30.1IFNG
37malaria30.0CFP, IL10, NF2, IFNG, TLR2
38lyme disease30.0LACTB, TLR2, CCL3
39crohn's disease30.0LYZ, CRP
40pulmonary tuberculosis30.0ADA, IL10, GUSB, MBL2, IFNG, TLR2
41peritonitis30.0ADA, LACTB, IL6, IL1B, CRP, TLR2
42behcet's disease30.0ADA, IL8, CRP, MBL2, CCL3
43glomerulonephritis30.0CFP, IL1B, MBL2, CAT
44eosinophilia30.0IL8, IL10, MBL2, IFNG
45kawasaki disease30.0MMP9, CRP, MBL2
46multiple myeloma30.0IL6, CCL3
47histiocytosis30.0LYZ
48adenoma30.0CXCL1
49stroke, ischemic30.0MMP9, CRP
50rheumatoid arthritis29.9ADA, MMP9, IL6, IL1B, IL8, IL10

Graphical network of the top 20 diseases related to Meningitis:



Diseases related to meningitis

Clinical Features for Meningitis

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Drugs & Therapeutics for Meningitis

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
See all sources

Approved drugs:

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Drug clinical trials:

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Search NIH Clinical Center for Meningitis

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Genetic Tests for Meningitis

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Anatomical Context for Meningitis

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32MalaCards
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MalaCards organs/tissues related to Meningitis:

32
Brain, Spinal cord, Testes, T cells, Bone, Pituitary, Liver, B cells, Endothelial, Lung, Skin, Myeloid, Breast, Cortex, Pineal, Bone marrow, Prostate, Eye, Medulla oblongata, Colon, Kidney, Monocytes, Adrenal gland, Spleen, Cervix, Tonsil, Heart, Temporal lobe, Thyroid

Animal Models for Meningitis or affiliated genes

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36MGI
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MGI Mouse Phenotypes related to Meningitis:

36 (show all 18)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:000538712.3CRP, MBL2, SOD2, IFNG, TLR2, CCL3
2MP:001076812.3CCL3, CAT, TLR2, IFNG, SOD2, GUSB
3MP:000538511.9TLR2, IFNG, SOD2, CRP, NTF3, CXCL1
4MP:000539711.9SOD2, IFNG, TLR2, CCL3, MBL2, GUSB
5MP:000537611.9ADA, CCL3, TLR2, IFNG, MBL2, GUSB
6MP:000537811.9CCL3, TLR2, IFNG, SOD2, GUSB, NTF3
7MP:000538611.7SOD2, IFNG, TLR2, CCL3, GUSB, NTF3
8MP:000538411.6CCL3, CAT, TLR2, IFNG, SOD2, GUSB
9MP:000200611.4IFNG, NF2, IL10, IL1B, IL6, MMP9
10MP:000537011.4TLR2, IFNG, SOD2, NF2, IL10, IL6
11MP:000539011.3GUSB, NF2, IL1B, IL6, CFP
12MP:000536711.2NF2, GUSB, SOD2, TLR2
13MP:001077111.1TLR2, SOD2, GUSB, IL6, MMP9
14MP:000538811.0NF2, IL6, MMP9
15MP:000538910.9SOD2, GUSB, NTF3, NF2, MMP9
16MP:000539110.8NF2, NTF3, SOD2
17MP:000363110.7NF2
18MP:000536910.5MMP9, NTF3, TLR2

Publications for Meningitis

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50PubMed
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Articles related to Meningitis:

(show top 50)    (show all 4899)
idTitleAuthorsYear
1
Bladder dysfunction and urodynamic study in tuberculous meningitis. (23472924)
2013
2
Cerebrospinal-fluid cytokine and chemokine profile in patients with pneumococcal and meningococcal meningitis. (23865742)
2013
3
High mortality amongst adolescents and adults with bacterial meningitis in sub-Saharan Africa: an analysis of 715 cases from Malawi. (23894538)
2013
4
Hydrocephalus is a rare outcome in community-acquired bacterial meningitis in adults: a retrospective analysis. (23855442)
2013
5
Three cases of neoplastic meningitis initially diagnosed with infectious meningitis in emergency department. (23840976)
2013
6
Comparison of clinical features in patients with persistent and nonpersistent cryptococcal meningitis: twelve years of clinical experience in four centers in China. (23795869)
2013
7
Effect of vaccines on bacterial meningitis worldwide. (23141619)
2012
8
Vaccination with Haemophilus influenzae type b conjugate vaccine reduces bacterial meningitis in Morocco. (22306854)
2012
9
Surgical treatment of neurologic complications of bacterial meningitis in children in Kosovo. (21873279)
2012
10
Tuberculous meningitis in adults: a review of a decade of developments focusing on prognostic factors for outcome. (22953709)
2012
11
Criteria indicating morbidity in tuberculous meningitis. (23866398)
2012
12
Computed tomography angiography in patients with tuberculous meningitis. (22446495)
2012
13
Lamotrigine and aseptic meningitis. (23082320)
2012
14
Aseptic meningitis following intravenous immunoglobulin therapy of common variable immunodeficiency. (22408675)
2011
15
A case of tuberculous meningitis with multiple intracranial tuberculomas and miliary tuberculosis and choroid tubercles. (21735111)
2011
16
Acute epidural abscess complicating pneumococcal meningitis in adult. (21119553)
2011
17
Patient Education Series. Viral meningitis in adults. (21403505)
2011
18
Syringomyelia associated with syphilitic spinal meningitis: real complication or possible association? (21339760)
2011
19
The implications of vaccines for prevention of bacterial meningitis. (20173637)
2010
20
Retinal hemorrhages associated with meningitis in a child with a congenital disorder of glycosylation. (19851897)
2009
21
Biomarkers of disease: cerebrospinal fluid vascular endothelial growth factor (VEGF) and stromal cell derived factor (SDF)-1 levels in patients with neoplastic meningitis (NM) due to breast cancer, lung cancer and melanoma. (19267183)
2009
22
Decompressive craniectomy in a case of intractable intracranial hypertension due to pneumococcal meningitis. (18566734)
2008
23
Aseptic meningitis. (17471037)
2007
24
Effects of inner ear trauma on the risk of pneumococcal meningitis. (17372082)
2007
25
Cerebral abscess associated with meningococcal meningitis. (16874183)
2006
26
Neonatal meningitis: what is the correlation among cerebrospinal fluid cultures, blood cultures, and cerebrospinal fluid parameters? (16585303)
2006
27
Induction of the antimicrobial peptide CRAMP in the blood-brain barrier and meninges after meningococcal infection. (17030578)
2006
28
Improving the bacteriological diagnosis of tuberculous meningitis. (14715783)
2004
29
Tuberculous meningitis. (15496620)
2004
30
Drug-induced aseptic meningitis. (12769786)
2003
31
Acute urinary retention as an unusual manifestation of aseptic meningitis. (12058890)
2002
32
Predictors of inpatient mortality in 190 adult patients with tuberculous meningitis. (12174481)
2002
33
Aseptic meningitis and cranial nerve palsy revealing adult-onset Still's disease. (10433601)
1999
34
Malignant meningeal melanoma. (10935858)
1998
35
Ibuprofen-induced aseptic meningitis in rheumatoid arthritis. (9296242)
1997
36
Parainfluenza virus type 2 meningitis and parotitis in an 11-year-old child. (7839170)
1995
37
Eosinophilic meningitis due to Angiostrongylus cantonensis. (8123100)
1993
38
C-reactive proteins, immunoglobulin profile and mycobacterial antigens in cerebrospinal fluid of patients with pyogenic and tuberculous meningitis. (1293215)
1992
39
Mesangiocapillary glomerulonephritis associated with meningococcal meningitis, C3 nephritic factor and persistently low complement C3 and C5. (1616831)
1992
40
Internuclear ophthalmoplegia in cryptococcal meningitis. (2023288)
1991
41
The discovery of Angiostrongylus cantonensis as a cause of human eosinophilic meningitis. (15463478)
1991
42
Listeria meningitis. (6517003)
1984
43
Listeria meningitis in an immunocompetent child. (6889588)
1982
44
Prognosis for survival in neonatal meningitis. (20312990)
1978
45
Letter: Hypoglycorrachia in young infants with viral meningitis. (1185362)
1975
46
Purpura fulminans associated with Neisseria catarrhalis septicemia and meningitis. (5795390)
1969
47
Purulent (non-meningococcal) meningitis in children. (5853119)
1965
48
Viral meningitis. (13525934)
1958
49
Syphilitic meningitis with negative blood and spinal fluid serology, report of a rare syndrome. (20994580)
1946
50
A CASE OF TUBERCULOUS CHOROIDITIS TERMINATED BY MENINGITIS AND MULTIPLE BRAIN ABSCESSES. (18168396)
1924

Genetic Variations for Meningitis

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Expression for genes affiliated with Meningitis

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Meningitis

Search GEO for disease gene expression data for Meningitis.

Pathways for genes affiliated with Meningitis

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Sources:
37NCBI BioSystems Database, 29KEGG, 51QIAGEN, 52R&D Systems, 12EMD Millipore, 53Reactome
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Pathways related to Meningitis according to GeneCards/GeneDecks:

(show all 50)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Hide members
11.3CCL3, TLR2, IFNG, IL10, IL8, IL1B
2
Hide members
11.3CCL3, TLR2, NTF3, CXCL1, IL10, IL8
311.2TLR2, IFNG, CXCL1, IL10, IL8, IL1B
411.1CAT, IFNG, SOD2, CRP, IL1B, IL6
5
Hide members
11.1TLR2, IFNG, IL8, IL1B, IL6, CFP
611.1CCL3, IFNG, CXCL1, IL8, IL1B, IL6
7
Immune response Bacterial infections in normal airways
Hide members
11.0TLR2, IFNG, IL8, IL1B, IL6
811.0IFNG, IL10, IL8, IL1B, IL6
911.0TLR2, CXCL1, IL8, IL1B, IL6
10
Hide members
11.0TLR2, IFNG, IL10, IL1B, IL6
11
Development PDGF signaling via STATs and NF-kB
Hide members
11.0IFNG, CXCL1, IL10, IL1B, IL6
1210.9TLR2, IL8, IL1B, IL6
13
Hide members
10.9TLR2, IL8, IL1B, IL6
1410.9IL10, IL8, IL1B, IL6
1510.9IL6, IL1B, IL8, IL10
16
Hide members
10.9IFNG, IL8, IL1B, IL6
17
Hide members
10.9TLR2, NTF3, IL1B, IL6
18
Hide members
10.9CXCL1, IL8, IL1B, IL6
19
Hide members
10.9IL6, IL1B, IL10, IFNG
2010.9IL6, IL1B, IL10, IFNG
2110.9MMP9, IL6, IFNG, TLR2
2210.9CXCL1, IL1B, IL6, MMP9
2310.9MMP9, IL6, IL1B, CXCL1
24
Immune response Lectin induced complement pathway
Hide members
10.8MBL2, CRP, CFP
2510.8IL6, IL8, TLR2
2610.8IL8, IL6, MMP9
2710.8MMP9, IL6, IL8
2810.8TLR2, IFNG, IL1B
2910.8IFNG, IL8, IL6
3010.8IL6, IL8, IFNG
3110.8IL10, IL1B, IL6
32
Cytokine production by Th17 cells in CF (Mouse model)
10.8CXCL1, IL8, IL6
3310.8CCL3, CXCL1, IL8
34
Hide members
10.8IL1B, IFNG, CCL3
35
Hide members
10.8IL10, IFNG, CCL3
36
Hide members
10.8CCL3, SOD2, CXCL1
37
Hide members
10.8CXCL1, NTF3, CCL3
38
Hide members
10.8CCL3, NTF3, CXCL1
3910.7CAT, SOD2
4010.7IL10, TLR2
4110.6IL8
4210.6IL8
4310.6TLR2
4410.6TLR2
45
Hide members
10.6TLR2
46
Hide members
10.6NTF3
47
Hide members
10.6IL6
48
Hide members
10.6IFNG
49
Transcription Role of VDR in regulation of genes involved in osteoporosis
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10.6IFNG
5010.6CXCL1

Compounds for genes affiliated with Meningitis

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Sources:
44Novoseek, 11DrugBank, 24HMDB, 28IUPHAR, 59Tocris Bioscience, 49PharmGKB, 2BitterDB
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Compounds related to Meningitis according to GeneCards/GeneDecks:

(show top 50)    (show all 219)
idCompoundScoreTop Affiliating Genes
1vegf4412.4ADA, CCL3, TLR2, IFNG, SOD2, MBL2
2cysteine4412.3MBL2, CCL3, CAT, SOD2, NTF3, NF2
3nitric oxide44 11 2414.2IL6, IL1B, IL10, NTF3, CCL3, CXCL1
4histamine44 28 2414.1CCL3, IFNG, GUSB, NTF3, ADA, IL6
5sb 20358044 5913.1TLR2, CAT, CCL3, MMP9, IFNG, CRP
6actinomycin d4412.1CCL3, CAT, TLR2, IFNG, SOD2, MMP9
7ccl344 2812.9CCL3, IL10, IL8, MMP9, TLR2, IFNG
8neopterin4411.9CCL3, IFNG, MBL2, CRP, IL10, IL8
9ly2940024411.8IL8, MMP9, IL6, IL10, IL1B, CCL3
10leukotriene b444 59 2413.8IL6, IL1B, IL8, GUSB, TLR2, CCL3
11lactate4411.7MMP9, SOD2, CCL3, GUSB, CRP, IL8
12simvastatin44 49 59 28 11 2416.7CCL3, IL10, CRP, TLR2, IL8, IL6
13methotrexate44 49 1113.7SOD2, ADA, MMP9, IL6, IL1B, CXCL1
14polymyxin b4411.7IL10, IFNG, MBL2, IL1B, IL6, TLR2
15rantes4411.7CXCL1, MBL2, IFNG, TLR2, IL1B, CCL3
16lipoteichoic acid4411.7MBL2, IL10, IL1B, IL6, TLR2, CCL3
178-isoprostane4411.7IL10, CRP, CCL3, CAT, IL8, IL6
18polyinosinic-polycytidylic acid4411.7IL6, IL1B, IL8, CCL3, TLR2, IFNG
19il 104411.6TLR2, CCL3, IL10, IL8, IL1B, IL6
20peptidoglycan44 2812.6MBL2, TLR2, IL10, IL8, IL1B, IL6
21pdtc4411.6MMP9, CAT, IL1B, IL6, IL8, SOD2
22dexamethasone44 49 28 1114.5SOD2, ADA, CXCL1, IL6, MMP9, TLR2
23genistein44 28 59 2 11 2416.5IL1B, IL6, IL8, NTF3, GUSB, SOD2
24superoxide44 2412.5CFP, IL1B, CXCL1, NTF3, GUSB, MBL2
25groalpha4411.5IL1B, IL6, IL10, CXCL1, CCL3, IL8
26etanercept44 49 1113.5IL1B, IL6, IL8, IL10, CRP, IFNG
27poly(i-c)4411.4CCL3, TLR2, IFNG, IL8, IL1B, IL6
28infliximab44 49 1113.4IL10, IL6, IL1B, CXCL1, CRP, IFNG
29ribavirin44 49 1113.4MBL2, IL10, MMP9, ADA, CCL3, IFNG
30bucillamine4411.4IFNG, IL1B, IL6, CRP, CAT
31mip 1alpha4411.3IL1B, IL8, IL10, CCL3, IL6
32cyclosporin a44 28 5913.3IFNG, CXCL1, ADA, CCL3
33il-124411.3IL1B, IFNG, IL10, IL8, IL6
34sp 60012544 5912.3IL1B, MMP9, IL8, TLR2, CCL3, IL6
35imiquimod44 28 59 1114.3TLR2, IFNG, IL10, IL6, IL8
36cycloheximide4411.3TLR2, CAT, SOD2
37triptolide4411.2IL6, CCL3, IFNG, IL8, IL1B
38aspartate4411.2NTF3, GUSB, MBL2, ADA
39n acetylcysteine4411.1IL6, IL1B, IL8, MMP9, CRP, SOD2
40gm-csf44 2812.1IL10, IFNG
41anaphylatoxin4411.0IL1B, CFP, IL8
42endotoxin4411.0CXCL1
43ivig4411.0IFNG, CRP
44taurine chloramine4411.0IL8, IFNG, IL1B, IL6
45pge24411.0MMP9
46gabexate mesilate4410.9MMP9
47prednisolone44 28 1112.8MBL2, CRP
48hbd24410.6TLR2, IL1B, IL6, IL8
49hydrocortisone44 2 59 1113.6IL8
50ulinastatin4410.6GUSB

GO Terms for genes affiliated with Meningitis

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Sources:
16Gene Ontology
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Cellular components related to Meningitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular spaceGO:00561511.8LYZ, CCL3, IFNG, MBL2, CRP, CXCL1
2extracellular regionGO:00557611.5NTF3, CRP, MBL2, IFNG, CCL3, CXCL1
3external side of plasma membraneGO:00989710.9ADA, IL6, IFNG, TLR2

Biological processes related to Meningitis according to GeneCards/GeneDecks:

(show all 29)
idNameGO IDScoreTop Affiliating Genes
1inflammatory responseGO:00695411.8LYZ, CCL3, TLR2, CRP, CXCL1, IL10
2negative regulation of cell proliferationGO:00828511.5SOD2, NF2, CXCL1, IL8, IL1B, IL6
3positive regulation of nitric oxide biosynthetic processGO:04542911.4TLR2, IFNG, SOD2, IL1B, IL6
4defense response to bacteriumGO:04274211.4IFNG, MBL2, IL10, CFP, LYZ
5positive regulation of transcription from RNA polymerase II promoterGO:04594411.4TLR2, IFNG, NTF3, IL10, IL1B, IL6
6immune responseGO:00695511.3TLR2, CXCL1, IL8, IL1B, CFP
7negative regulation of growth of symbiont in hostGO:04413011.3IL10, MBL2, IFNG, TLR2
8defense response to Gram-positive bacteriumGO:05083011.3TLR2, MBL2, CRP, IL6
9neutrophil chemotaxisGO:03059311.3IL1B, IL8, IFNG, CCL3
10positive regulation of NF-kappaB transcription factor activityGO:05109211.3CAT, TLR2, IL1B, IL6
11response to hypoxiaGO:00166611.2ADA, CRP, SOD2, CAT
12lipopolysaccharide-mediated signaling pathwayGO:03166311.1IL1B, TLR2, CCL3
13positive regulation of tumor necrosis factor productionGO:03276011.1CCL3, TLR2, IFNG
14acute-phase responseGO:00695311.1MBL2, CRP, IL6
15positive regulation of interleukin-6 productionGO:03275511.1IL6, IL1B, TLR2
16positive regulation of T cell proliferationGO:04210211.1IFNG, IL1B, IL6
17neutrophil apoptotic processGO:00178111.0IL6, IFNG
18positive regulation of calcidiol 1-monooxygenase activityGO:06055911.0IL1B, IFNG
19cellular response to lipopolysaccharideGO:07122211.0IFNG, IL10, IL8
20positive regulation of interleukin-6 biosynthetic processGO:04541010.9IFNG, IL1B
21positive regulation of MHC class II biosynthetic processGO:04534810.9IFNG, IL10
22response to drugGO:04249310.9IL6, IL10, SOD2, IFNG
23negative regulation of lipid storageGO:01088810.9CRP, IL6
24opsonizationGO:00822810.9MBL2, CRP
25cell-cell signalingGO:00726710.8IL1B, IL10, NTF3, CCL3
26negative regulation of interleukin-17 productionGO:03270010.8IFNG, TLR2
27positive regulation of chemokine biosynthetic processGO:04508010.8IL1B, IFNG
28response to molecule of bacterial originGO:00223710.7IL10, IL8
29positive regulation of sequence-specific DNA binding transcription factor activityGO:05109110.5IL10, IL1B, IL6

Molecular functions related to Meningitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1receptor bindingGO:00510210.9CXCL1, NTF3, MBL2, CAT
2growth factor activityGO:00808310.9IL6, IL10, CXCL1, NTF3
3cytokine activityGO:00512510.8IFNG, IL10, IL1B, IL6
4chemokine activityGO:00800910.5IL8, CXCL1, CCL3

Products for genes affiliated with Meningitis

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  • Antibodies
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Sources for Meningitis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet