MCID: MNN007
MIFTS: 37

Meningocele malady

Summaries for Meningocele

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63Wikipedia, 32MalaCards
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Wikipedia:63 Spina bifida (Latin: \"split spine\") is a developmental congenital disorder caused by the incomplete... more...

MalaCards: Meningocele, also known as meningocele, nos, is related to caudal regression syndrome and microphthalmia. An important gene associated with Meningocele is VANGL1 (VANGL planar cell polarity protein 1). Affiliated tissues include spinal cord, bone and brain, and related mouse phenotypes are limbs/digits/tail and hearing/vestibular/ear.

Aliases & Classifications for Meningocele

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8Disease Ontology, 42NIH Rare Diseases, 10DISEASES, 44Novoseek, 60UMLS, 34MeSH, 56SNOMED-CT
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Aliases & Descriptions:

meningocele 8 42 10 44 60
meningocele, nos 8


External Ids:

Disease Ontology8 DOID:1088
MeSH34 D008588

Related Diseases for Meningocele

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Meningocele:



Diseases related to meningocele

Clinical Features for Meningocele

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Drugs & Therapeutics for Meningocele

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Meningocele

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Anatomical Context for Meningocele

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32MalaCards
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MalaCards organs/tissues related to Meningocele:

32
Spinal cord, Bone, Brain, Skin, Eye, Uterus, Heart

Animal Models for Meningocele or affiliated genes

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36MGI
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MGI Mouse Phenotypes related to Meningocele:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053719.1GDF6, VANGL1, NF1
2MP:00053779.0VANGL1, GDF6, NF1
3MP:00028738.0NF1, NCOA1, MNX1, VANGL1
4MP:00036317.9VANGL1, NCOA1, NF1, MNX1, GDF6
5MP:00053787.8GDF6, NCOA1, NF1, MNX1, VANGL1

Publications for Meningocele

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50PubMed
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Articles related to Meningocele:

(show top 50)    (show all 495)
idTitleAuthorsYear
1
Management of a parturient with an anterior sacral meningocele. (23122279)
2013
2
Huge anterior sacral meningocele simulating bladder retention. (23374854)
2013
3
Coexistent malignant peripheral nerve sheath tumor and lateral spinal meningoceles. (23066463)
2012
4
A large intrathoracic meningocele in a patient with neurofibromatosis-1. (20526399)
2010
5
Endoscopic repair of a rare basioccipital meningocele associated with recurrent meningitis. (20672942)
2010
6
Spinal meningocele due to iatrogenic dural puncture during epidural analgesia for childbirth: 5-year history of headache with a spinal etiology. (19951031)
2009
7
Neural tube defect in a 4000-year-old Egyptian infant mummy: a case of meningocele from the museum of anthropology and ethnography of Turin (Italy). (19136285)
2009
8
Optic nerve sheath meningocele. (19668771)
2008
9
Giant plexiform neurofibroma and suboccipital meningocele manifesting as segmental neurofibromatosis. (18574335)
2008
10
Sacral intraspinal meningocele in a patient presenting with abdominal pain. Case report. (17644921)
2007
11
Dented rudimentary meningocele. (18021861)
2007
12
Currarino triad as an anterior sacral meningocele. (15292645)
2004
13
A neurofibromatosis type 1 patient with severe kyphoscoliosis and intrathoracic meningocele. (12637072)
2003
14
Intrathoracic giant meningocele developing hydrothorax: a case report. (12468984)
2002
15
Tibial hemimelia, meningocele, and abdominal hernia in Shorthorn cattle. (11055885)
2000
16
Suboccipital meningocele presenting as a huge retropharyngeal mass in a patient with neurofibromatosis Type 1. Case report. (10470829)
1999
17
Diffuse neurofibroma of the orbit associated with temporal meningocele and neurofibromatosis-1. (9852542)
1998
18
A case of anterior sacral meningocele totally excised using the posterior sagittal approach. (9165463)
1997
19
Lateral meningocele syndrome: three new patients and review of the literature. (9188658)
1997
20
CSF rhinorrhea from a transclival meningocele demonstrated by MR. (8800338)
1996
21
Cerebellar dermoid tumor and occipital meningocele in a monozygotic twin: clues to the embryogenesis of craniospinal dysraphism. (7585671)
1995
22
Sequestrated meningocele of the scalp: diagnostic value of hair anomalies. (7899180)
1994
23
A patient with facial abnormality, imperforate anus, tetrapolyhypodactyly and meningocele: a variable manifestation of the polyoligodactyly/imperforate anus/vertebral anomalies syndrome. (7724288)
1994
24
Tethered spinal cord and an intradural lipoma associated with a meningocele in a Manx-type cat. (8244864)
1993
25
MRI demonstration of cervical meningocele. (8232890)
1993
26
Localized hypertrophic mononeuropathy involving spinal roots and associated with sacral meningocele. Case report. (8410259)
1993
27
Meningocele manquAc: radiologic findings with clinical correlation. (1636517)
1992
28
Intrathoracic meningocele. (1533325)
1992
29
Rudimentary meningocele of the skin. Clinicopathologic features and differential diagnosis. (1918505)
1991
30
Thoracic meningocele in neurofibromatosis: CT and MR findings. (1939761)
1991
31
Thoraco-abdominal enteric duplication with meningocele, skeletal anomalies and dextrocardia. (2226553)
1990
32
Anterior sacral meningocele occurring in one family. An autosomal dominantly inherited condition. (2334530)
1990
33
Anterolateral lumbar meningocele presenting as an ovarian cyst, in a patient with neurofibromatosis. (2555098)
1989
34
Carcinoid tumor in a presacral teratoma associated with an anterior sacral meningocele: case report and review of the literature. (3362327)
1988
35
Posterolateral extradural approach for total excision of lateral thoracic meningocele: technical report. (3696416)
1987
36
Parietal foramina complicated by meningocele. (4064024)
1985
37
Anterior sacral meningocele: review of the literature. (6828997)
1983
38
Dandy-Walker cyst associated with occipital meningocele. (7071719)
1982
39
Intraspinal meningocele. (7215093)
1980
40
Pharyngeal surgery: meningitis following accidental rupture of a meningocele. (4505894)
1972
41
The occult intrasacral meningocele. (5764664)
1969
42
Intrathoracic meningocele associated with cutaneous neurofibromatosis. (13884957)
1961
43
Intrathoracic meningocele. (13626535)
1959
44
Spina bifida with meningocele. (13621867)
1958
45
Intrathoracic meningocele; review of the literature and report of a case. (13520232)
1958
46
Spontaneous fracture of the femur in an infant with a large occipital meningocele. (13089088)
1953
47
Intrathoracic meningocele; excision, with three and one-half years follow-up. (14909325)
1952
48
Meningocele following hemilaminectomy; report of 2 cases. (15429977)
1950
49
Hydrocephalus, and hydrocephalus with meningocele; their treatment by choroid plexectomy. (18913774)
1948
50
Bilateral Petit's hernia and an anterior sacral meningocele occurring in the same patient. (20983096)
1946

Genetic Variations for Meningocele

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Expression for genes affiliated with Meningocele

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Meningocele

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Pathways for genes affiliated with Meningocele

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Compounds for genes affiliated with Meningocele

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GO Terms for genes affiliated with Meningocele

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16Gene Ontology
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Biological processes related to Meningocele according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1positive regulation of neuron differentiationGO:0456669.1GDF6, NCOA1

Products for genes affiliated with Meningocele

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Sources for Meningocele

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet