MCID: MNN007
MIFTS: 37

Meningocele malady

Categories: Rare diseases, Neuronal diseases, Fetal diseases

Aliases & Classifications for Meningocele

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Aliases & Descriptions for Meningocele:

Name: Meningocele 10 45 47 12 36 65
Congenital Meningocele 65
 
Spinal Meningocele 65
Meningocele, Nos 10

Classifications:



External Ids:

Disease Ontology10 DOID:1088
MeSH36 D008588
UMLS65 C0025299, C0009730, C1261470

Summaries for Meningocele

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MalaCards based summary: Meningocele, also known as congenital meningocele, is related to caudal regression syndrome and neuronitis. An important gene associated with Meningocele is MNX1 (Motor Neuron And Pancreas Homeobox 1). Affiliated tissues include bone, t cells and liver, and related mouse phenotypes are limbs/digits/tail and digestive/alimentary.

Related Diseases for Meningocele

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Graphical network of the top 20 diseases related to Meningocele:



Diseases related to meningocele

Symptoms for Meningocele

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Drugs & Therapeutics for Meningocele

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Meningocele


Cochrane evidence based reviews: meningocele

Genetic Tests for Meningocele

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Anatomical Context for Meningocele

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MalaCards organs/tissues related to Meningocele:

33
Bone, T cells, Liver, Lung, Thyroid, Brain, Prostate

Animal Models for Meningocele or affiliated genes

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MGI Mouse Phenotypes related to Meningocele:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053718.7ALX3, NF1, SATB2, VANGL1
2MP:00053818.7ALX3, MNX1, NF1, SATB2
3MP:00036318.4ALX3, MNX1, NF1, NOTCH3, VANGL1
4MP:00053798.4ALX3, MNX1, NF1, NOTCH3, SATB2
5MP:00053808.4ALX3, NF1, NOTCH3, SATB2, VANGL1
6MP:00053908.0ALX3, MNX1, NF1, NOTCH3, SATB2
7MP:00053887.9ALX3, MNX1, NF1, NOTCH3, SATB2, VANGL1
8MP:00053857.8MNX1, NF1, NOTCH3, SATB2, VANGL1
9MP:00107687.6ALX3, MNX1, NF1, NOTCH3, SATB2, VANGL1
10MP:00053787.5ALX3, MNX1, NF1, NOTCH3, SATB2, VANGL1

Publications for Meningocele

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Articles related to Meningocele:

(show top 50)    (show all 525)
idTitleAuthorsYear
1
Unexpected cause of superior vena cava syndrome. (26312222)
2015
2
Renal cell carcinoma: review of etiology, pathophysiology and risk factors. (26558360)
2015
3
Rab8 binding to immune cell-specific adaptor LAX facilitates formation of trans-Golgi network-proximal CTLA-4 vesicles for surface expression. (24515439)
2014
4
Thromboembolism in pediatric inflammatory bowel disease: the blood stops here. (23760227)
2013
5
Novel protein isoforms of carcinoembryonic antigen are secreted from pancreatic, gastric and colorectal cancer cells. (24070190)
2013
6
Intracranial hemorrhages and late hemorrhagic disease associated cholestatic liver disease. (22327309)
2013
7
Responsiveness to low-dose warfarin associated with genetic variants of VKORC1, CYP2C9, CYP2C19, and CYP4F2 in an Indonesian population. (22855348)
2013
8
Use of Recombinant Thrombomodulin in Disseminated Intravascular Coagulation Complicated Hemophagocytic Lymphohistiocytosis. (23912823)
2013
9
Epidermal growth factor receptor is essential for Toll-like receptor 3 signaling. (22810896)
2012
10
Analysis of anti-MA1llerian hormone (AMH) and its receptor (AMHR2) genes in patients with persistent MA1llerian duct syndrome. (23295284)
2012
11
Reversible diffuse white matter lesion in Alagille syndrome. (21723462)
2011
12
Surgery for hydrocele in children-an avoidable excess? (22152892)
2011
13
Snail1 is stabilized by O-GlcNAc modification in hyperglycaemic condition. (20959806)
2010
14
Subarachnoid hemorrhage and hydrocephalus causing neurogenic pulmonary edema. (20602055)
2010
15
Inhibition of tau fibrillization by oleocanthal via reaction with the amino groups of tau. (19549281)
2009
16
Distinct subdomains of the KCNQ1 S6 segment determine channel modulation by different KCNE subunits. (19687231)
2009
17
Preliminary evaluation of a vaginal cream containing lactoferrin in the treatment of vulvovaginal candidosis]. (18487962)
2008
18
Evolution of a family of metazoan active-site-serine enzymes from penicillin-binding proteins: a novel facet of the bacterial legacy. (18226203)
2008
19
Bradykinin enhances reactive oxygen species generation, mitochondrial injury, and cell death induced by ATP depletion--a role of the phospholipase C-Ca(2+) pathway. (17664134)
2007
20
Short half-lives of ataxia-associated aprataxin proteins in neuronal cells. (17485165)
2007
21
The SERPINE2 gene is associated with chronic obstructive pulmonary disease. (16358219)
2006
22
Postprandial interstitial insulin concentrations in type 2 diabetes relatives. (16684121)
2006
23
Ghrelin and glucagon-like peptide 1 concentrations, 24-h satiety, and energy and substrate metabolism during a high-protein diet and measured in a respiration chamber. (16400055)
2006
24
Study on clinical and biological characteristics of childhood acute leukemia with MLL gene rearrangements]. (16383239)
2005
25
Aph-1 interacts at the cell surface with proteins in the active gamma-secretase complex and membrane-tethered Notch. (15715652)
2005
26
Misfolding of major histocompatibility complex class I molecules in activated T cells allows cis-interactions with receptors and signaling molecules and is associated with tyrosine phosphorylation. (15471856)
2004
27
Chondroblastoma of bone--not a " benign disease": clinico-pathologic observations on sixty cases. (16295467)
2004
28
Targeting tumor necrosis factor-alpha in the therapy of psoriasis. (15180471)
2004
29
Inhibition of hepatic gluconeogenesis and enhanced glucose uptake contribute to the development of hypoglycemia in mice bearing interleukin-1beta- secreting tumor. (15297440)
2004
30
Induction of apoptosis by bleomycin in p53-null HL-60 leukemia cells. (14719107)
2004
31
Is neuropeptide Y responsible for constitutional delay of puberty in girls? A preliminary report. (15625769)
2004
32
Molecular characterization of human prostate carcinoma cell lines. (14518029)
2003
33
DNA self-recognition in the structure of Pot1 bound to telomeric single-stranded DNA. (14614509)
2003
34
Crossreacting drugs and chemicals. (12668895)
2003
35
Cytokine-mediated host responses during schistosome infections; walking the fine line between immunological control and immunopathology. (12521263)
2002
36
Identification and characterization of four novel phosphorylation sites (Ser31, Ser325, Thr336 and Thr366) on LKB1/STK11, the protein kinase mutated in Peutz-Jeghers cancer syndrome. (11853558)
2002
37
Functional requirement of aquaporin-5 in plasma membranes of sweat glands. (11773623)
2002
38
Increased sensitivity to IL-4 in patients with allergic bronchopulmonary aspergillosis. (11146389)
2000
39
Pax2, Otx2, Gbx2 and Fgf8 expression in early otic vesicle development. (10906468)
2000
40
Evaluation of the activated partial thromboplastin time (APTT) sensitivity to heparin using five commercial reagents: implications for therapeutic monitoring. (9915232)
1998
41
Photodynamic therapy of superficial basal cell carcinoma by instillation of aminolevulinic acid and irradiation with visible light. (9420532)
1997
42
TP53 mutational pattern in Spanish and Polish non-small cell lung cancer patients: null mutations are associated with poor prognosis. (9416838)
1997
43
Transforming properties of the cottontail rabbit papillomavirus oncoproteins Le6 and SE6 and of the E8 protein. (8648665)
1996
44
Two alpha subunit donor splice site mutations cause human trifunctional protein deficiency. (7738175)
1995
45
Immunohistochemical localisation of cytokeratin and vimentin intermediate filament proteins in canine mammary tumours. (7514803)
1994
46
Molecular cloning and characterization of the human cardiac Na+/Ca2+ exchanger cDNA. (1374913)
1992
47
Novel, potent aldose reductase inhibitors: 3,4-dihydro-4-oxo-3-[[5-(trifluoromethyl)-2-benzothiazolyl] methyl]-1-phthalazineacetic acid (zopolrestat) and congeners. (1899452)
1991
48
An unusual form of chronic myeloproliferative disorder. Aleukemic basophilic leukemia. (2031458)
1991
49
Again about bone marrow necrosis: particular diagnostic aspects. (2638585)
1989
50
Prognosis in paranoid schizophrenia on the basis of the Rorschach. (13061662)
1953

Variations for Meningocele

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Expression for genes affiliated with Meningocele

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Search GEO for disease gene expression data for Meningocele.

Pathways for genes affiliated with Meningocele

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GO Terms for genes affiliated with Meningocele

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Biological processes related to Meningocele according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1embryonic skeletal system morphogenesisGO:00487049.8ALX3, SATB2
2regulation of transcription, DNA-templatedGO:00063558.4HSF4, MNX1, SATB2
3transcription, DNA-templatedGO:00063518.1ALX3, HSF4, MNX1, SATB2

Sources for Meningocele

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet