MCID: MNN007
MIFTS: 38

Meningocele malady

Summaries for Meningocele

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64Wikipedia, 33MalaCards
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Wikipedia:64 Spina bifida (Latin: \"split spine\") is a developmental congenital disorder caused by the incomplete... more...

MalaCards: Meningocele, also known as meningocele, nos, is related to caudal regression syndrome and microphthalmia. An important gene associated with Meningocele is VANGL1 (VANGL planar cell polarity protein 1). Affiliated tissues include skin, spinal cord and brain, and related mouse phenotypes are limbs/digits/tail and hearing/vestibular/ear.

Aliases & Classifications for Meningocele

Sources:
8Disease Ontology, 43NIH Rare Diseases, 10DISEASES, 45Novoseek, 61UMLS, 35MeSH, 57SNOMED-CT
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Aliases & Descriptions:

meningocele 8 43 10 45 61
meningocele, nos 8


External Ids:

Disease Ontology8 DOID:1088
MeSH35 D008588

Related Diseases for Meningocele

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Meningocele:



Diseases related to meningocele

Clinical Features for Meningocele

Drugs & Therapeutics for Meningocele

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials, 61UMLS, 41NDF-RT
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Meningocele

Anatomical Context for Meningocele

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33MalaCards
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MalaCards organs/tissues related to Meningocele:

33
Skin, Spinal cord, Brain, Uterus, Heart, Small intestine, Dorsal root ganglion, Uterus corpus

Animal Models for Meningocele or affiliated genes

Sources:
37MGI, 28inGenious Targeting Laboratory
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MGI Mouse Phenotypes related to Meningocele:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053719.1GDF6, VANGL1, NF1
2MP:00053779.0NF1, VANGL1, GDF6
3MP:00028738.0VANGL1, MNX1, NF1, NCOA1
4MP:00036317.9GDF6, VANGL1, MNX1, NF1, NCOA1
5MP:00053787.8NCOA1, NF1, MNX1, VANGL1, GDF6

Publications for Meningocele

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51PubMed
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Articles related to Meningocele:

(show top 50)    (show all 496)
idTitleAuthorsYear
1
The communication between the cystic meningocele cavity and thecal sac: how can we evaluate? (23892393)
2013
2
Re: Castelli et al.: huge anterior sacral meningocele simulating bladder retention (Urology 2013;81:e9-e10). (23896109)
2013
3
Chest wall bleeding with giant intrathoracic meningocele in neurofibromatosis type 1. (21118835)
2011
4
Conception in an infertile patient following obliteration of a huge anterior sacral meningocele: case report. (19693516)
2010
5
Venous stroke can be the unusual clinical presentation of an arising naso-ethmoidal encephalo-meningocele in adulthood. (24209400)
2009
6
Congenital cystic eye with meningocele. (21887201)
2009
7
Rapidly progressive paraplegia due to an extradural lumbar meningocele mimicking a cyst. Case report. (17633492)
2007
8
Laparoscopic treatment of anterior sacral meningocele. (17905071)
2007
9
Anterior sacral meningocele. A case report. (17571042)
2007
10
Presacral mass consisting of a meningocele and a Tarlov cyst: successful surgical treatment based on pathogenic hypothesis. (16322904)
2006
11
Lateral meningocele syndrome: vertical transmission and expansion of the phenotype. (15666314)
2005
12
Epithelioid hemangioendothelioma and multiple thoraco-lumbar lateral meningoceles: two rare pathological entities in a patient with NF-1. (15688204)
2005
13
Meningocele-induced positional syncope and retinal hemorrhage. (12748081)
2003
14
Pseudo-meningocele following apparently uncomplicated lumbar puncture--a common procedure with a rare complication. (12505204)
2002
15
Sequestrated meningocele of the scalp. (11704362)
2001
16
Anterior sacral meningocele in a patient with Marfan syndrome. (11327300)
2001
17
Anterior sacral meningocele completely occupied by an epidermoid tumor. (10361973)
1999
18
Occult intrasacral meningocele with tethered cord--case report. (7623956)
1995
19
Recurrent meningitis in a case of congenital anterior sacral meningocele and agenesis of sacral and coccygeal vertebrae. (8729777)
1995
20
Intrasacral meningocele. Report of a case. (7788339)
1995
21
Trigonocephaly associated with anterior basal meningocele. Case report. (8965126)
1995
22
Linkage analysis of a candidate locus (HLA) in autosomal dominant sacral defect with anterior meningocele. (7977450)
1994
23
Anterior sacral meningocele and Marfan syndrome: a review. (8470436)
1993
24
Anterior sacral meningocele presenting as a pelvic/abdominal mass in a patient with Marfan syndrome. (8347646)
1993
25
Treatment of anterior sacral meningocele--case report. (7505898)
1993
26
Meningoceles, meningomyeloceles, and encephaloceles: a neuro-dermatopathologic study of 132 cases. (1918504)
1991
27
Rudimentary meningocele: a variant of "primary cutaneous meningioma". (2474587)
1989
28
Anterior sacral meningocele and tuberculous spondylitis of the sacrum in a patient with neurofibromatosis. Case report and review of the literature. (2518511)
1989
29
Dermoid tumours occurring at the site of previous meningocele repair. (3208469)
1988
30
Anterior sacral meningocele in pregnancy. (3808520)
1987
31
Meningocele communicating to the lower eyelid discovered during removal of xanthelasmata. (3697571)
1986
32
Nasal aplasia associated with meningocele and submucous cleft palate. (3996279)
1985
33
Intrathoracic meningocele: an uncommon entity. (3931657)
1985
34
Meningocele of the asterion. (7060413)
1982
35
Anterior sacral meningocele: a case report. (721283)
1978
36
Anterior sacral meningocele in association with Marfan's syndrome. (5578713)
1971
37
Cord paralysis following injection into traumatic cervical meningocele. Complication of stellate ganglion block. (4393352)
1970
38
Anterior sacral meningocele as a gynecologic problem. Report of a case. (5474007)
1970
39
Meningocele mediastini. (5903612)
1966
40
INTRATHORACIC MENINGOCELE. (14256321)
1965
41
ANTERIOR MENINGOCELE. (14338497)
1965
42
DIASTEMATOMYELIA AND THE KLIPPEL-FEIL SYNDROME. RELATIONSHIP TO HYDROCEPHALUS, SYRINGOMYELIA, MENINGOCELE, MENINGOMYELOCELE, AND INIENCEPHALUS. (14105037)
1964
43
Anterior sacral meningocele. (14407731)
1959
44
Traumatic nasal meningocele. (13474437)
1957
45
Anterior sacral meningocele. (13327237)
1956
46
Anterior sacral meningocele. (13148427)
1954
47
Intrathoracic meningocele; a case report. (14920692)
1952
48
Intrathoracic meningocele. (18144673)
1949
49
Occult meningocele of the sacrum; report of three cases. (18891295)
1948
50
Case reports and technical notes; anterior sacral meningocele. (21007731)
1945

Genetic Variations for Meningocele

Expression for genes affiliated with Meningocele

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Meningocele

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Pathways for genes affiliated with Meningocele

Compounds for genes affiliated with Meningocele

GO Terms for genes affiliated with Meningocele

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16Gene Ontology
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Biological processes related to Meningocele according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1positive regulation of neuron differentiationGO:0456669.1GDF6, NCOA1

Products for genes affiliated with Meningocele

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Sources for Meningocele

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet