MCID: MNN020
MIFTS: 34

Meningococcal Infection malady

Rare diseases, Infectious diseases categories

Summaries for Meningococcal Infection

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Sources:
35MedlinePlus, 66Wikipedia, 34MalaCards
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MedlinePlus:35 Meningococci are a type of bacteria that cause serious infections. the most common infection is meningitis, which is an inflammation of the thin tissue that surrounds the brain and spinal cord. meningococci can also cause other problems, including a serious bloodstream infection called sepsis. meningococcal infections can spread from person to person. risk factors include age - it is more common in infants, teens, and young adults living in close quarters, such as in college dorms or military settings certain medical conditions, such as not having a spleen travel to areas where meningococcal disease is common in its early stages, you may have flu-like symptoms and a stiff neck. but the disease can progress quickly and can be fatal. early diagnosis and treatment are extremely important. lab tests on your blood and cerebrospinal fluid can tell if you have it. treatment is with antibiotics. since the infection spreads from person to person, family members may also need to be treated. a vaccine can prevent meningococcal infections.

MalaCards: Meningococcal Infection, also known as meningococcal infections, is related to neisseria meningitidis infection and systemic lupus erythematosus. An important gene associated with Meningococcal Infection is ROM1 (retinal outer segment membrane protein 1), and among its related pathways are Complement Pathway and Complement and coagulation cascades. Affiliated tissues include testes, brain and spinal cord, and related mouse phenotype cardiovascular system.

Wikipedia:66 Meningococcal disease describes infections caused by the bacterium Neisseria meningitidis (also termed... more...

Aliases & Classifications for Meningococcal Infection

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Sources:
44NIH Rare Diseases, 35MedlinePlus, 63UMLS, 26ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases, Infectious diseases


Aliases & Descriptions:

meningococcal infection 44
meningococcal infections 35 63


External Ids:

ICD1026 A39

Related Diseases for Meningococcal Infection

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Sources:
18GeneCards, 19GeneDecks
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Graphical network of the top 20 diseases related to Meningococcal Infection:



Diseases related to meningococcal infection

Symptoms for Meningococcal Infection

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Drugs & Therapeutics for Meningococcal Infection

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Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials
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Approved drugs:

Search CenterWatch for Meningococcal Infection

Drug clinical trials:

Search ClinicalTrials for Meningococcal Infection

Search NIH Clinical Center for Meningococcal Infection

Search CenterWatch for Meningococcal Infection

Genetic Tests for Meningococcal Infection

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Anatomical Context for Meningococcal Infection

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34MalaCards
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MalaCards organs/tissues related to Meningococcal Infection:

34
Testes, Brain, Spinal cord, Spleen, Skin, Monocytes, Thyroid, Eye, Cortex, Bone, Adrenal cortex

Animal Models for Meningococcal Infection or affiliated genes

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Sources:
38MGI
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MGI Mouse Phenotypes related to Meningococcal Infection:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053859.0ROM1, ADRB1, CFP

Publications for Meningococcal Infection

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Sources:
53PubMed
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Articles related to Meningococcal Infection:

(show top 50)    (show all 234)
idTitleAuthorsYear
1
Severe meningococcal infection: a review of epidemiology, diagnosis, and management. (23830646)
2013
2
Review of meningococcal infection in children at a United Kingdom hospital. (19388559)
2009
3
Susceptibility to meningococcal infection--nature versus nurture? (18779704)
2008
4
Single nucleotide polymorphisms in genes of circulatory homeostasis in surviving pediatric intensive care patients with meningococcal infection. (18679149)
2008
5
Unusual sequelae of meningococcal infection: a case report of hepatic dysfunction, protracted neurological complications and late cutaneous manifestations associated with serogroup y. (12643869)
2003
6
Few university students from overseas have been vaccinated against meningococcal infection. (11154644)
2001
7
Prevention of meningococcal infection in laboratory workers--an audit of practice in England and Wales. (11525001)
2001
8
Outbreak of group C meningococcal infection affecting two preschool nurseries. (11014030)
2000
9
Risk of meningococcal infection in college students. (10349894)
1999
10
False positive diagnosis of meningococcal infection by the IS1106 PCR ELISA. (9627955)
1998
11
Bacterial meningitis and meningococcal infection. (9529632)
1998
12
The pattern of interleukin-1beta (IL-1beta) and its modulating agents IL-1 receptor antagonist and IL-1 soluble receptor type II in acute meningococcal infections. (9242541)
1997
13
Meningococcal infection from saliva. (8937287)
1996
14
Meningococcal infection in Africa. (8680504)
1996
15
Risk factors for Neisseria meningitidis carriage in a school during a community outbreak of meningococcal infection. (8870623)
1996
16
Correlation between proinflammatory cytokines and antiinflammatory mediators and the severity of disease in meningococcal infections. (7622886)
1995
17
Inaccuracy of notifications of meningococcal infection in Scotland. (7615384)
1995
18
The worldwide prevention of meningococcal infection. Still an elusive goal. (7823389)
1995
19
Initial management of suspected meningococcal infection. Parenteral benzylpenicillin is vital. (7819968)
1994
20
Hereditary deficiency of the seventh component of complement and recurrent meningococcal infection: investigations of an Irish family using a novel haemolytic screening assay for complement activity and C7 M/N allotyping. (7523157)
1994
21
Clinical problem-solving: prevention of meningococcal infection. (8289870)
1994
22
Predictors of outcome in acute meningococcal infection in children. (8440116)
1993
23
Diagnosing meningococcal infection. Don't delay giving antibiotics. (8343721)
1993
24
Meningococcal infection: diagnostic and therapeutic pitfalls. (1530701)
1992
25
Laboratory-acquired meningococcal infection. (1285190)
1992
26
Meningococcal infection: evidence for school transmission. (1753114)
1991
27
Selective C7 complement deficiency causing recurrent meningococcal infection. (2071909)
1991
28
Prevalence of hereditary properdin, C7 and C8 deficiencies in patients with meningococcal infections. (2397612)
1990
29
Meningococcal infection. A review based upon papers presented at the 155th meeting of the Pathological Society of Great Britain and Ireland. Southampton, 8 July 1987. (3392726)
1988
30
Rifampin-resistant meningococcal infection in a patient given rifampin chemoprophylaxis. (3144922)
1988
31
Epidemiology of meningococcal infection. (3107645)
1987
32
Meningococcal infection and complement deficiency. (3670957)
1987
33
Management of skin loss in meningococcal infection. (3318641)
1987
34
Group B meningococcal infection in children during an epidemic in Cape Town, South Africa. (2439004)
1987
35
Increased tissue thromboplastin activity in monocytes of patients with meningococcal infection: related to an unfavourable prognosis. (6845273)
1983
36
Deaths from meningococcal infection. (7185992)
1982
37
Serum immunoglobulin levels in various forms of meningococcal infection and in meningococcus carriers. (564371)
1977
38
Comparative study of group A and group C meningococcal infection. (860875)
1977
39
Letter: Concomitant hepatitis B and meningococcal infection. (946197)
1976
40
Letter: Meningococcal infection. (4425865)
1974
41
Immunoprophylaxis of meningococcal infection. (4204814)
1974
42
Recurrent meningococcal infection with an antigenically identical strain. (4134964)
1974
43
Spread of meningococcal infection within households. (4134961)
1974
44
The fibrin(ogen) degradation products and platelets in meningococcal infection. (4213439)
1973
45
Meningococcal infection unresponsive to cephalothin. (5790503)
1969
46
Possibilities of application of complement fixation, indirect hemagglutination and fluorescent antibody tests to epidemiology of meningococcal infection. (5326082)
1966
47
Factors in the prognosis of meningococcal infection. Review of 63 cases with emphasis on recognition and management of the severely ill patient. (5903316)
1966
48
Meningococcal infections; with particular reference to fulminating meningococcemia (Waterhouse-Friderichsen syndrome) treated with cortisone and norepinephrine. (13202023)
1954
49
Aureomycin in the treatment of meningococcal infection. (13016914)
1953
50
Pathological changes in adrenal cortex of mouse during experimental meningococcal infection. (14844310)
1951

Variations for Meningococcal Infection

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Expression for genes affiliated with Meningococcal Infection

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Sources:
2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Meningococcal Infection

Search GEO for disease gene expression data for Meningococcal Infection.

Pathways for genes affiliated with Meningococcal Infection

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Sources:
51PathCards, 54QIAGEN, 61Thomson Reuters, 56Reactome, 58SinoBiological, 31KEGG, 39NCBI BioSystems Database
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Pathways related to Meningococcal Infection according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
Immune response Alternative complement pathway61
Immune response Lectin Induced complement pathway61
Immune response Classic complement pathway61
9.1CFD, CFP
2
Show member pathways
Complement Activation, Classical Pathway39
Complement and Coagulation Cascades39
9.0CPB2, CFD

Compounds for genes affiliated with Meningococcal Infection

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GO Terms for genes affiliated with Meningococcal Infection

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17Gene Ontology
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Cellular components related to Meningococcal Infection according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular spaceGO:0056158.5CPB2, CFD, CFP

Biological processes related to Meningococcal Infection according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1complement activation, alternative pathwayGO:0069579.0CFD, CFP
2proteolysisGO:0065089.0CPB2, CFD
3complement activationGO:0069568.8CFD, CFP

Products for genes affiliated with Meningococcal Infection

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Meningococcal Infection

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet