Aliases & Classifications for Meningococcemia

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Aliases & Descriptions for Meningococcemia:

Name: Meningococcemia 46 48 66

Classifications:



Summaries for Meningococcemia

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Wikipedia:69 Meningococcal disease describes infections caused by the bacterium Neisseria meningitidis (also termed... more...

MalaCards based summary: Meningococcemia is related to uveitis and bacteremia. An important gene associated with Meningococcemia is IL1B (Interleukin 1 Beta), and among its related pathways are Interleukin-1 processing and Cytokines and Inflammatory Response. Affiliated tissues include skin, bone and testes, and related mouse phenotypes are hematopoietic system and cardiovascular system.

Related Diseases for Meningococcemia

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Diseases related to Meningococcemia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 123)
idRelated DiseaseScoreTop Affiliating Genes
1uveitis29.9BPI, SERPINE1
2bacteremia29.3BPI, MBL2
3c4b deficiency29.3CFP, MBL2
4waterhouse-friderichsen syndrome10.6
5gastric cancer risk after h. pylori infection10.5IL1B, IL1RN
6silo filler's disease10.5IL1B, IL1RN
7non-secretory myeloma10.5IL1B, IL1RN
8cinca syndrome10.5IL1B, IL1RN
9oral candidiasis10.5IL1B, IL1RN
10keloids10.5IL1B, IL1RN
11senile cataract10.5IL1B, IL1RN
12osmotic diarrhea10.5IL1B, IL1RN
13intestinal variant cervical mucinous adenocarcinoma10.5IL1B, SERPINE1
14tibialis tendinitis10.5IL1B, IL1RN
15cervical mullerian papilloma10.4IL1B, SERPINE1
16catatrichy10.4PROC, SERPINE1
17diabetic cataract10.4IL1A, IL1B
18functional colonic disease10.4PROC, SERPINE1
19pediatric supratentorial ependymoma10.4IL1B, IL1RN
20rectosigmoid junction neoplasm10.4IL1A, IL1B
21sterility due to immotile flagella10.4IL1A, IL1B
22orbital lymphangioma10.4IL1A, IL1B
23partial of retinal vein occlusion10.4IL1B, IL1RN
24periodic paralyses10.4IL1A, IL1B
25liver disease10.4IL1A, IL1B
26pseudoretinitis pigmentosa10.4IL1A, IL1B
27evans' syndrome10.4IL1B, IL1RN
28accessory nerve disease10.4IL1A, IL1B
29hypercementosis10.3IL1A, IL1RN
30benign lymphoepithelial lesion of salivary gland10.3IL1A, IL1B
31corneal intraepithelial neoplasm10.3BPI, IL1B
32meningitis10.3
33neonatal period electroclinical syndrome10.3IL1A, IL1B
34sternum lymphoma10.3IL1B, IL1RN
35common cold10.3IL1A, IL1B
36nervous system cancer10.3IL1A, IL1B
37purpura10.3
38lung hilum cancer10.2IL1B, SERPINE1
39intervertebral disc disease10.2IL1A, IL1B
40asbestosis10.2IL1A, IL1B
41atypical follicular adenoma10.2IL1B, SERPINE1
42purpura fulminans10.2
43toxic maculopathy10.2IL1A, IL1RN
44pregnancy loss, recurrent 210.2PROC, SERPINE1
45lung sarcoma10.2IL1A, IL1B
46atrial septal defect coronary sinus10.1IL1B, MBL2
47disseminated intravascular coagulation10.1
48meningococcal meningitis10.1
49peri-anal fistula10.1IL1A, IL1B, IL1RN
50anaerobic meningitis10.1IL1A, IL1B, IL1RN

Graphical network of the top 20 diseases related to Meningococcemia:



Diseases related to meningococcemia

Symptoms for Meningococcemia

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Drugs & Therapeutics for Meningococcemia

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Drugs for Meningococcemia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
HydrocortisonePhase 260250-23-75754, 657311
Synonyms:
(11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione
(11beta)-11,17,21-Trihydroxypregn-4-ene-3,20-dione
11-Hydrocortisone
11-beta-Hydrocortisone
11-beta-Hydroxycortisone
11a-Hydroxycorticosterone
11alpha-Hydroxycorticosterone
11b,17,21-Trihydroxyprogesterone
11b-Hydrocortisone
11b-Hydroxycortisone
11beta,17,21-Trihydroxyprogesterone
11beta,17alpha,21-Trihydroxy-4-pregnene-3,20-dione
11beta-Hydrocortisone
11beta-Hydroxycortisone
11beta-hydrocortisone
11β-hydrocortisone
17-Hydroxycorticosterone
17a-Hydroxycorticosterone
17alpha-Hydroxycorticosterone
2v95
4-Pregnen-11beta,17alpha,21-triol-3,20-dione
4-Pregnene-11alpha,21-triol 3,20-dione
4-Pregnene-11b,17a,21-triol-3,20-dione
50-23-7
8056-08-4
80562-38-5
8063-42-1
AC-12902
AC1L1L2B
ACETASOL HC
ACETIC ACID W/ HYDROCORTISONE
AI3-25006
AKOS001582651
Acticort
Acticort (TN)
Aeroseb HC
Aeroseb-HC
Ala-Cort
Ala-Scalp
Alacort
Algicirtis
Alphaderm
Amberin
Anflam
Anti-inflammatory hormone
Anucort
Anucort-HC
Anusol HC
Anusol HC (TN)
Aquacort
Aquanil HC
B48448A1-24BA-47CA-8D9E-43E5BC949386
BPBio1_000544
BRD-K93568044-001-03-1
BSPBio_000494
Balneol-hc
Barseb HC
Basan-Corti
Beta-hc
Bio-0648
C00735
C21H30O5
CCRIS 5854
CHEBI:17650
CHEMBL389621
CID5754
COR-OTICIN
CPD000653523
CaldeCORT Spray
Cetacort
Chronocort
Clear aid
Cleiton
Cobadex
Colocort
Colocort (TN)
Compound F
Compound F (kendall)
Cor-Tar-Quin
Corhydron
Cort-Dome
Cort-Quin
Cortanal
Cortef
Cortef (TN)
Cortenema
Cortesal
Corticreme
Cortifair
Cortifan
Cortifoam
Cortiment
Cortisol
Cortisol alcohol
Cortisol, Hydrocortisone
Cortisolonum
Cortisporin
Cortisporin Otico
Cortispray
Cortizol
Cortolotion
Cortonema
Cortoxide
Cortril
Cremesone
Cremicort-H
Cutisol
Cyclodextrin-encapsulated hydrocortisone
D00088
DB00741
DB07886
Delacort
Derm-Aid
Dermacort
Dermaspray
Dermil
Dermocortal
Dermolate
Dihydrocostisone
Dioderm
Dome-cort
Domolene-HC
Drotic
DuoCort
EINECS 200-020-1
EU-0100594
Ef corlin
Efcorbin
Efcortelan
Efcortelin
Eldecort
Eldercort
Epicort
Epicortisol
Epiderm H
Esiderm H
Evacort
Ficortril
Fiocortril
Flexicort
Foille Insetti
Genacort
Genacort (lotion)
Glycort
Gyno-Cortisone
H 4001
H-Cort
H0135_SIGMA
H0396_SIGMA
H0888_SIGMA
H3160_SIGMA
H4001_SIGMA
H6909_SIGMA
HC
HC #1
 
HC #4
HC (HYDROCORTISONE)
HMS1569I16
HMS2090M04
HSDB 3339
HYDROCORTISONE AND ACETIC ACID
HYDROCORTISONE IN ABSORBASE
Heb Cort
Heb-Cort
Hi-cor
Hidalone
Hidro-Colisona
Hidrocortisona
Hidrocortisona [INN-Spanish]
Hycort
Hycortol
Hycortole
Hydracort
Hydrasson
Hydro-Adreson
Hydro-Colisona
Hydro-RX
Hydro-colisona
Hydrocort
Hydrocortal
Hydrocorticosterone
Hydrocortisone
Hydrocortisone (JP15/USP/INN)
Hydrocortisone Acetate
Hydrocortisone Base
Hydrocortisone Butyrate
Hydrocortisone Sodium Phosphate
Hydrocortisone Valerate
Hydrocortisone [INN:BAN:JAN]
Hydrocortisone alcohol
Hydrocortisone base
Hydrocortisone free alcohol
Hydrocortisone solution
Hydrocortisone-Water Soluble
Hydrocortisonum
Hydrocortisonum [INN-Latin]
Hydrocortistab
Hydrocortisyl
Hydrocortone
Hydroskin
Hydroxycortisone
Hysone
Hytisone
Hytone
Hytone (TN)
Hytone lotion
Idrocortisone
Idrocortisone [DCIT]
Incortin-H
Incortin-hydrogen
Kendall'S compound F
Kendall's compound F
Komed HC
Kyypakkaus
LMST02030001
LS-7439
Lacticare HC
Lacticare-HC
Lactisona
Lopac0_000594
Lubricort
MLS000069609
MLS001148103
MLS002207135
MLS002222189
Maintasone
Medicort
Meusicort
Mildison
Milliderm
MolPort-001-794-637
NCGC00022848-06
NCGC00022848-07
NCGC00022848-09
NCGC00022848-12
NCI60_000118
NSC 10483
NSC-10483
NSC10483
Neo-Cort-Dome
Neo-Cortef
Neosporin-H Ear
Nogenic HC
Nutracort
Nystaform-HC
ORLEX HC
Optef
Otalgine
Otic-Neo-Cort-Dome
Otobiotic
Otocort
Otosone-F
Pediotic Suspension
Penecort
Permicort
Polcort H
Preparation H Hydrocortisone Cream
Prepcort
Prestwick0_000447
Prestwick1_000447
Prestwick2_000447
Prestwick3_000447
Prestwick_265
Prevex HC
Proctocort
Proctofoam
Proctozone HC
Protocort
Racet
Rectasol-HC
Rectoid
Reichstein'S substance M
Reichstein's substance M
Remederm HC
S1696_Selleck
SAM002264617
SMP1_000156
SMR000059022
SMR000653523
SPBio_002433
Sanatison
Scalp-Cort
Scalpicin Capilar
Schericur
Scheroson F
Sigmacort
Signef
Stie-cort
Stiefcorcil
Synacort
Systral Hydrocort
Tarcortin
Texacort
Texacort lotion 25
Timocort
Topicort
Transderma H
Traumaide
UNII-WI4X0X7BPJ
UPCMLD-DP133
UPCMLD-DP133:001
Uniderm
Vioform-Hydrocortisone
VoSol HC
Vytone
Zenoxone
[3H]cortisol
component of Lubricort
component of Neo-Cort-Dome
component of Otalgine
hydrocortisone
2
butyric acidPhase 2350107-92-6264
Synonyms:
1-Butanoate
1-Butanoic acid
1-Butyrate
1-Butyric acid
1-Propanecarboxylate
1-Propanecarboxylic acid
Butanate
Butanic acid
Butanoate
Butanoic acid
Buttersaeure
Butyrate
 
Butyric acid
Ethylacetate
Ethylacetic acid
Honey robber
Kyselina maselna
N-Butanoate
N-Butanoic acid
N-Butyrate
N-Butyric acid
Propanecarboxylate
Propanecarboxylic acid
Propylformate
Propylformic acid

Interventional clinical trials:

idNameStatusNCT IDPhase
1Study of Menactra® in US Adolescents When Administered Concomitantly With Tdap VaccineCompletedNCT00777257Phase 4
2Immunology and Safety of Menactra® in Children in Saudi ArabiaCompletedNCT00539032Phase 3
3Study of a Booster Dose of Meningococcal Diphtheria Toxoid Conjugate Vaccine in AdolescentsCompletedNCT00777790Phase 2
4Study of Reduced Dose of Menomune® in Children Who Previously Received Meningococcal Diphtheria Toxoid Conjugate VaccineCompletedNCT00772070Phase 2
5Study of Antibody Responses After a Dose of Tetravalent Meningococcal Diphtheria Conjugate Vaccine in ChildrenCompletedNCT00771849Phase 2
6Antibody Persistence and Booster Dose Response in Subjects Who Received Menactra® Three Years Earlier in Study MTA26CompletedNCT00700713Phase 2
7Evaluation of Corticosteroid Therapy in Childhood Severe Sepsis - a Randomised Pilot StudyCompletedNCT00732277Phase 2
8Antibody Responses Following Meningococcal Tetravalent (A, C, Y, and W-135) Conjugate Vaccination in Healthy AdultsTerminatedNCT00772629Phase 2
9Correlation Between Cytokines and the Severity of Meningococcal DiseaseCompletedNCT01133834

Search NIH Clinical Center for Meningococcemia

Genetic Tests for Meningococcemia

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Anatomical Context for Meningococcemia

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MalaCards organs/tissues related to Meningococcemia:

34
Skin, Bone, Testes, Atrioventricular node, Endothelial, Colon, Heart

Animal Models for Meningococcemia or affiliated genes

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MGI Mouse Phenotypes related to Meningococcemia:

39
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053977.7IL1A, IL1B, IL1RN, MBL2, PROC, SERPINE1
2MP:00053857.4CFP, IL1A, IL1B, IL1RN, PROC, SERPINE1
3MP:00053877.2CFP, IL1A, IL1B, IL1RN, MBL2, PROC
4MP:00053766.9CFP, IL1A, IL1B, IL1RN, MBL2, PROC

Publications for Meningococcemia

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Articles related to Meningococcemia:

(show top 50)    (show all 292)
idTitleAuthorsYear
1
MBL2 Deficiency is Associated with Higher Genomic Bacterial Loads during Meningococcemia in Young Children. (24977653)
2014
2
Fatal meningococcemia. (23882342)
2011
3
Dermacase. Question: Can you identify this condition? Diagnosis: Meningococcemia. (20841592)
2010
4
Giant condyloma with demise secondary to meningococcemia in an infant boy. (19596116)
2009
5
Purpuric rash of meningococcemia. (18438796)
2008
6
Protein C promoter polymorphisms associate with sepsis in children with systemic meningococcemia. (17569089)
2007
7
4G4G genotype of the plasminogen activator inhibitor-1 promoter polymorphism associates with disseminated intravascular coagulation in children with systemic meningococcemia. (17697137)
2007
8
Polymorphisms in the interleukin-1 gene cluster in children and young adults with systemic meningococcemia. (16510430)
2006
9
Local Shwartzman reaction in the rat induced by endotoxin and ischemia: potential model for skin necrosis in meningococcemia. (16864696)
2006
10
Diagnosing meningococcemia as a cause of sepsis. (15857559)
2005
11
Meningococcemia update vaccination and chemoprophylaxis. (16085964)
2005
12
Osteonecrosis after meningococcemia and disseminated intravascular coagulation. (14628777)
2003
13
Outcome in meningococcemia: a relationship between quantity and quality? (11588489)
2001
14
Meningococcemia following tonsillectomy. (11868768)
2001
15
Bactericidal/permeability-increasing protein--lessons learned from the phase III, randomized, clinical trial of rBPI21 for adjunctive treatment of children with severe meningococcemia. (11445748)
2001
16
Do new strategies in meningococcemia produce better outcomes? (11007200)
2000
17
An open-label study of the role of adjuvant hemostatic support with protein C replacement therapy in purpura fulminans-associated meningococcemia. (11090052)
2000
18
Abdominal pain and fever--an unusual presentation of meningococcemia. (10451180)
1999
19
Meningococcemia with vitreous opacities: endophthalmitis or vitreous hemorrhage? (10037579)
1999
20
Acute meningococcemia. (9293739)
1997
21
Meningococcemia: heading off a killer. (20086968)
1996
22
Meningococcemia: recognizing and reducing complications in pediatric patients. (7780842)
1994
23
Chronic meningococcemia in an immunocompetent girl. (7928036)
1994
24
Fatal course in severe meningococcemia: clinical predictors and effect of transfusion therapy. (8222686)
1993
25
Purpura fulminans and adrenal hemorrhage due to group Y meningococcemia in an elderly woman. (1901668)
1991
26
Orthopedic sequelae of meningococcemia. (2008386)
1991
27
Post-traumatic meningococcemia in a patient with deficiency of the C7 complement component. (2264845)
1990
28
Once daily ceftriaxone for meningococcemia and meningococcal meningitis. (3054778)
1988
29
Chronic meningococcemia. (3123131)
1987
30
Benign meningococcemia with IgG and IgM antimeningococcal antibodies measured by ELISA. (3126548)
1987
31
Chronic meningococcemia. (6523901)
1984
32
Amputation following meningococcemia. A sequela to purpura fulminans. (6705382)
1984
33
Severe pulmonary edema in meningococcemia. (6839627)
1983
34
Chronic meningococcemia. (6772999)
1980
35
Neonatal meningococcal meningitis and meningococcemia. (443224)
1979
36
Benign meningococcemia in childhood. A report of five cases with clinical and diagnostic remarks. (97774)
1978
37
Staphylococcal septicemia and disseminated intravascular coagulation. Staphylococcus aureus endocarditis mimicking meningococcemia. (879923)
1977
38
Meningococcemia presenting as septic arthritis: case report. (4208724)
1974
39
Atrioventricular-node inflammation--mechanism of sudden death in protracted meningococcemia. (4623015)
1972
40
Heparin therapy in fulminant meningococcemia. (5804192)
1969
41
Hypofibrinogenemia and thrombocytopenia with meningococcemia. (4225764)
1967
42
CHRONIC MENINGOCOCCEMIA. FURTHER COMMENTS ON THE PATHOGENESIS OF ASSOCIATED SKIN LESIONS. (14152125)
1964
43
Chronic meningococcemia. (13340577)
1956
44
Skin sloughs in patients with meningococcemia. (13245438)
1955
45
Meningococcal infections; with particular reference to fulminating meningococcemia (Waterhouse-Friderichsen syndrome) treated with cortisone and norepinephrine. (13202023)
1954
46
Generalized cutaneous herpes simplex; report of a case complicating meningococcemia. (14955744)
1952
47
Meningococcemia. (14782309)
1950
48
Meningococcemia. (20268800)
1947
49
Meningococcemia. (20278670)
1947
50
Meningococcemia with acute leptomeningitis and acute myocarditis. (21000434)
1946

Variations for Meningococcemia

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Expression for genes affiliated with Meningococcemia

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Search GEO for disease gene expression data for Meningococcemia.

Pathways for genes affiliated with Meningococcemia

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GO Terms for genes affiliated with Meningococcemia

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Cellular components related to Meningococcemia according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1extracellular regionGO:00055766.6CFP, IL1A, IL1B, IL1RN, MBL2, PROC
2extracellular spaceGO:00056156.4BPI, CFP, IL1A, IL1B, IL1RN, MBL2

Biological processes related to Meningococcemia according to GeneCards Suite gene sharing:

(show all 18)
idNameGO IDScoreTop Affiliating Genes
1fever generationGO:000166010.2IL1A, IL1B
2positive regulation of monocyte chemotactic protein-1 productionGO:007163910.2IL1A, IL1B
3negative regulation of blood coagulationGO:003019510.2PROC, SERPINE1
4ectopic germ cell programmed cell deathGO:003523410.2IL1A, IL1B
5positive regulation of interleukin-2 biosynthetic processGO:004508610.2IL1A, IL1B
6positive regulation of cell divisionGO:005178110.1IL1A, IL1B
7negative regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:200124010.1IL1A, IL1B
8extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.1IL1A, IL1B
9positive regulation of interleukin-8 productionGO:00327579.9IL1B, SERPINE1
10positive regulation of vascular endothelial growth factor productionGO:00105759.9IL1A, IL1B
11positive regulation of interleukin-6 productionGO:00327559.8IL1A, IL1B
12positive regulation of mitotic nuclear divisionGO:00458409.6IL1A, IL1B
13defense response to Gram-negative bacteriumGO:00508299.6BPI, SERPINE1
14complement activationGO:00069569.6CFP, MBL2
15positive regulation of angiogenesisGO:00457669.5IL1A, IL1B, SERPINE1
16positive regulation of phagocytosisGO:00507669.4IL1B, MBL2
17defense response to bacteriumGO:00427428.8BPI, CFP, MBL2
18immune responseGO:00069558.1BPI, CFP, IL1A, IL1RN

Molecular functions related to Meningococcemia according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1interleukin-1 receptor bindingGO:000514910.1IL1A, IL1B
2cytokine activityGO:00051259.2IL1A, IL1B, IL1RN

Sources for Meningococcemia

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet