MCID: MNN009
MIFTS: 39

Meningoencephalitis malady

Summaries for Meningoencephalitis

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Wikipedia:63 Meningoencephalitis (/m??n????.?n?s?f??la?t?s/; from Greek: meninges- membranes; enkephalos brain; and... more...

MalaCards based summary: Meningoencephalitis is related to encephalitis and myositis. An important gene associated with Meningoencephalitis is C9 (complement component 9), and among its related pathways are Cytosolic sensors of pathogen-associated DNA and Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways. The compounds ptca and cerivastatin have been mentioned in the context of this disorder. Affiliated tissues include brain, pituitary and skin, and related mouse phenotype immune system.

Disease Ontology:9 A central nervous system disease that involves encephalitis which occurs along with meningitis.

Aliases & Classifications for Meningoencephalitis

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Sources:
9Disease Ontology, 11DISEASES, 43Novoseek, 60UMLS, 33MeSH, 38NCIt, 55SNOMED-CT
See all sources

Meningoencephalitis, Aliases & Descriptions:

Name: Meningoencephalitis 9 11 43 60


External Ids:

Disease Ontology9 DOID:10554
MeSH33 D008590
SNOMED-CT55 7125002
NCIt38 C34813

Related Diseases for Meningoencephalitis

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Graphical network of the top 20 diseases related to Meningoencephalitis:



Diseases related to meningoencephalitis

Symptoms for Meningoencephalitis

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Drugs & Therapeutics for Meningoencephalitis

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Drug clinical trials:

Search ClinicalTrials for Meningoencephalitis

Search NIH Clinical Center for Meningoencephalitis

Genetic Tests for Meningoencephalitis

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Anatomical Context for Meningoencephalitis

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MalaCards organs/tissues related to Meningoencephalitis:

31
Brain, Pituitary, Skin, Kidney, T cells, B cells, Testes, Spinal cord, Thyroid, Endothelial

Animal Models for Meningoencephalitis or affiliated genes

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MGI Mouse Phenotypes related to Meningoencephalitis:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053878.1C5, CCL5, APP, DARC

Publications for Meningoencephalitis

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Articles related to Meningoencephalitis:

(show top 50)    (show all 645)
idTitleAuthorsYear
1
Successful treatment of a case of primary amoebic meningoencephalitis: How important is history taking. (25722558)
2015
2
Genetic and pathological characteristics of Cryptococcus gattii and Cryptococcus neoformans var. neoformans from meningoencephalitis in autochthonous goats and mouflons, Sardinia, Italy. (25840469)
2015
3
Cytomegalovirus meningoencephalitis after rituximab treatment for primary central nervous system lymphoma. (25607329)
2015
4
Paroxysmal Sympathetic Hyperactivity in Critically Ill Children with Encephalitis and Meningoencephalitis. (25724178)
2015
5
Acute phenytoin intoxication in a 4-year-old mimicking viral meningoencephalitis. (23814089)
2013
6
Establishment of a model of Streptococcus iniae meningoencephalitis in Nile tilapia (Oreochromis niloticus). (23218409)
2013
7
Retrospective study of Mycoplasma gallisepticum meningoencephalitis in six turkey flocks in western France. (22878056)
2013
8
Aseptic meningoencephalitis mimicking transient ischaemic attacks. (23325395)
2013
9
Pharmacodynamics of liposomal amphotericin B and flucytosine for cryptococcal meningoencephalitis: safe and effective regimens for immunocompromised patients. (23599314)
2013
10
Fumagillin-induced aseptic meningoencephalitis in a kidney transplant recipient with microsporidiosis. (23025483)
2012
11
Meningoencephalitis due to Listeria monocytogenes in a pregnant rhesus macaque (Macaca mulatta). (23114049)
2012
12
Pituitary tumor apoplexy presenting as infective meningoencephalitis. (21630035)
2012
13
Long-term immunosuppressive therapy with cyclosporine plus prednisolone for necrotizing meningoencephalitis in a Pekingese dog. (22214856)
2012
14
HHV6 meningoencephalitis sequelae in previously healthy children. (22802100)
2012
15
A rare case of survival from primary amebic meningoencephalitis. (22557831)
2012
16
Pituitary apoplexy can mimic acute meningoencephalitis or subarachnoid haemorrhage. (21975129)
2011
17
Tick-borne meningoencephalitis in a 4.5-month-old infant. (20814849)
2011
18
Meningoencephalitis or meningitis in relapsing polychondritis: four case reports and a literature review. (22051026)
2011
19
Thrombotic thrombocytopenic purpura mimicking an acute meningoencephalitis. (21485766)
2011
20
Meningoencephalitis associated with hepatitis A infection: a case report and review of literature. (20555050)
2010
21
Pathology in practice. Necrotizing pyogranulomatous meningoencephalitis with intralesional fungal hyphae, consistent with Cladophialophora bantiana. (20113240)
2010
22
Primary amoebic meningoencephalitis: first reported case from Rohtak, North India. (20191204)
2009
23
The rationale for integrated childhood meningoencephalitis surveillance: a case study from Cambodia. (19551241)
2009
24
Update on emerging infections: News from the Centers for Disease Control and Prevention. Primary amebic meningoencephalitis-Arizona, Florida, and Texas, 2007. (19708086)
2009
25
A case of Listeria meningoencephalitis complicated by hydrocephalus in an immunocompetent infant. (18463893)
2009
26
Cogan's syndrome: a rare cause of meningoencephalitis. (19491118)
2009
27
Magnetic resonance imaging characteristics of necrotizing meningoencephalitis in Pug dogs. (19645838)
2009
28
Treatment of meningoencephalitis of unknown origin in a dog. (19448257)
2009
29
Necrotizing meningoencephalitis in five Chihuahua dogs. (18487490)
2008
30
Meningoencephalitis associated with human parvovirus B19. (19076847)
2008
31
Meningoencephalitis due to Toscana virus in a French traveler returning from central Italy. (19006512)
2008
32
Regression of white matter MRI abnormalities in nonvasculitic autoimmune inflammatory meningoencephalitis following intravenous immunoglobulin. (17389804)
2007
33
Anthrax meningoencephalitis successfully treated. (17661992)
2007
34
Non-suppurative meningoencephalitis of unknown origin in cats and dogs: an immunohistochemical study. (17275833)
2007
35
Virological and immunological characteristics of fatal Epstein-Barr virus mononucleosis in a 17-year-old Caucasian male presenting with meningoencephalitis and hemophagocytic syndrome. (17849323)
2007
36
Ventricular pneumocephalus and septic meningoencephalitis secondary to dorsal rhinotomy and nasal polypectomy in a dog. (16842045)
2006
37
Acute meningoencephalitis caused by adenovirus serotype 26. (16877305)
2006
38
Meningoencephalitis associated with Staphylococcus warneri in a dog. (17004952)
2006
39
Tickborne meningoencephalitis, first case after 19 years in northeastern Germany. (15834983)
2005
40
Pyogranulomatous meningoencephalitis in a goat due to Corynebacterium ulcerans. (15786922)
2005
41
Meningoencephalitis associated with passive immunization of a transgenic murine model of Alzheimer's amyloidosis. (15862291)
2005
42
Pathologic quiz case: headache in an 8-year-old child. Primary amebic meningoencephalitis due to Naegleria fowleri. (14736265)
2004
43
Clinical and neuroinflammatory responses to meningoencephalitis in substance P receptor knockout mice. (12805119)
2003
44
Primary amebic meningoencephalitis--Georgia, 2002. (14534512)
2003
45
Intrathecal humoral immune response in pediatric patients with meningoencephalitis due to Coxsackie B5]. (10363312)
1999
46
From the Centers for Disease Control. Primary amebic meningoencephalitis--North Carolina, 1991. (1640602)
1992
47
Herpes zoster ophthalmicus with delayed cerebral infarction and meningoencephalitis. (3311326)
1987
48
Coxsackievirus B3 producing fatal meningoencephalitis in a patient with X-linked agammaglobulinemia. (6293302)
1983
49
Primary amebic meningoencephalitis. (4620947)
1972
50
Mumps meningoencephalitis with and without parotitis. (18147966)
1949

Variations for Meningoencephalitis

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Expression for genes affiliated with Meningoencephalitis

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Search GEO for disease gene expression data for Meningoencephalitis.

Pathways for genes affiliated with Meningoencephalitis

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Pathways related to Meningoencephalitis according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.5CCL5, APP
2
Show member pathways
9.5CCL5, APP
3
Show member pathways
9.4DARC, CCL5
4
Show member pathways
9.2C5, C9
5
Show member pathways
Immune response Alternative complement pathway58
Immune response Lectin Induced complement pathway58
Immune response Classic complement pathway58
9.2C5, C9
6
Show member pathways
Complement Activation, Classical Pathway36
Complement and Coagulation Cascades36
9.2C5, C9
78.8C5, CCL5, C9
8
Show member pathways
8.7C5, C9, APP
9
Show member pathways
8.1DARC, APP, CCL5, C5
10
Show member pathways
8.1DARC, APP, CCL5, C5

Compounds for genes affiliated with Meningoencephalitis

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Compounds related to Meningoencephalitis according to GeneCards Suite gene sharing:

(show all 28)
idCompoundScoreTop Affiliating Genes
1ptca439.8CCL5, CHKB
2cerivastatin49 43 28 1212.8CCL5, CHKB
3propranolol43 28 49 24 1213.8APP, CCL5
4risperidone43 49 28 59 24 1214.8CHKB, APP
5azathioprine43 2 49 1212.7CCL5, CHKB
6lead439.7CHKB, CCL5
7lovastatin43 49 59 28 1213.7CHKB, APP
8gf 109203x43 5910.6CCL5, APP
9egcg439.6CCL5, APP
10anaphylatoxin439.5C5, CCL5
11choline43 24 1211.4APP, CHKB
12endotoxin439.4CCL5, CHKB
13simvastatin43 49 59 28 24 1214.4CCL5, CHKB, APP
14tacrolimus43 49 1211.4CCL5, CHKB, APP
15aspirin43 49 28 2412.3CCL5, CHKB, APP
16methotrexate49 43 1211.3CCL5, CHKB, APP
17epinephrine43 24 1211.3APP, CHKB, CCL5
18cyclosporin a43 28 5911.3APP, CHKB, CCL5
19creatinine439.3APP, CHKB, CCL5
20heparin43 28 24 1212.3CCL5, CHKB, APP
21h2o2439.3CCL5, CHKB, APP
22cholesterol43 28 24 1212.2CCL5, CHKB, APP
23dexamethasone43 49 28 1212.2APP, CHKB, CCL5
24folate439.2CCL5, APP
25vegf439.2CCL5, CHKB, APP
26glutamate439.1CCL5, CHKB, APP
27cysteine439.0CCL5, CHKB, APP
28alanine438.7DARC, APP, CHKB, CCL5

GO Terms for genes affiliated with Meningoencephalitis

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Cellular components related to Meningoencephalitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1membrane attack complexGO:00055798.9C5, C9
2extracellular regionGO:00055768.3C5, CCL5, C9, APP

Biological processes related to Meningoencephalitis according to GeneCards Suite gene sharing:

(show all 8)
idNameGO IDScoreTop Affiliating Genes
1chemokine-mediated signaling pathwayGO:00700989.5DARC, CCL5
2complement activation, alternative pathwayGO:00069579.4C5, C9
3regulation of complement activationGO:00304499.4C5, C9
4complement activation, classical pathwayGO:00069589.2C9, C5
5chemotaxisGO:00069359.2C5, CCL5
6cellular calcium ion homeostasisGO:00068749.1C5, CCL5
7inflammatory responseGO:00069548.6C5, CCL5, DARC
8innate immune responseGO:00450878.4C5, C9, APP

Molecular functions related to Meningoencephalitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1chemokine activityGO:00080099.2C5, CCL5

Products for genes affiliated with Meningoencephalitis

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Sources for Meningoencephalitis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet