MCID: MNN009
MIFTS: 47

Meningoencephalitis malady

Neuronal diseases category
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Summaries for Meningoencephalitis

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Wikipedia:65 Meningoencephalitis (/m??n????.?n?s?f??la?t?s/; from Greek: meninges- membranes; enkephalos brain; and... more...

MalaCards based summary: Meningoencephalitis is related to myositis and encephalitis. An important gene associated with Meningoencephalitis is C9 (complement component 9), and among its related pathways are Cytosolic sensors of pathogen-associated DNA and Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways. The compounds ptca and cerivastatin have been mentioned in the context of this disorder. Affiliated tissues include brain, pituitary and skin, and related mouse phenotype immune system.

Disease Ontology:8 A central nervous system disease that involves encephalitis which occurs along with meningitis.

Aliases & Classifications for Meningoencephalitis

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Sources:
8Disease Ontology, 10DISEASES, 44Novoseek, 62UMLS, 57SNOMED-CT, 39NCIt, 34MeSH
See all sources

Meningoencephalitis, Aliases & Descriptions:

Name: Meningoencephalitis 8 10 44 62


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Neuronal diseases


External Ids:

Disease Ontology8 DOID:10554
NCIt39 C34813
SNOMED-CT57 7125002
MeSH34 D008590

Related Diseases for Meningoencephalitis

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Graphical network of the top 20 diseases related to Meningoencephalitis:



Diseases related to meningoencephalitis

Symptoms for Meningoencephalitis

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Drugs & Therapeutics for Meningoencephalitis

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Drug clinical trials:

Search ClinicalTrials for Meningoencephalitis

Search NIH Clinical Center for Meningoencephalitis

Genetic Tests for Meningoencephalitis

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Anatomical Context for Meningoencephalitis

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MalaCards organs/tissues related to Meningoencephalitis:

32
Brain, Pituitary, Skin, Kidney, T cells, Thyroid, Testes, B cells, Spinal cord, Endothelial

Animal Models for Meningoencephalitis or affiliated genes

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MGI Mouse Phenotypes related to Meningoencephalitis:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053878.1C5, CCL5, APP, DARC

Publications for Meningoencephalitis

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Articles related to Meningoencephalitis:

(show top 50)    (show all 632)
idTitleAuthorsYear
1
Acute phenytoin intoxication in a 4-year-old mimicking viral meningoencephalitis. (23814089)
2013
2
Establishment of a model of Streptococcus iniae meningoencephalitis in Nile tilapia (Oreochromis niloticus). (23218409)
2013
3
Retrospective study of Mycoplasma gallisepticum meningoencephalitis in six turkey flocks in western France. (22878056)
2013
4
Aseptic meningoencephalitis mimicking transient ischaemic attacks. (23325395)
2013
5
Pharmacodynamics of liposomal amphotericin B and flucytosine for cryptococcal meningoencephalitis: safe and effective regimens for immunocompromised patients. (23599314)
2013
6
Complete genome sequence of Streptococcus agalactiae strain SA20-06, a fish pathogen associated to meningoencephalitis outbreaks. (23991251)
2013
7
Fumagillin-induced aseptic meningoencephalitis in a kidney transplant recipient with microsporidiosis. (23025483)
2012
8
Meningoencephalitis due to Listeria monocytogenes in a pregnant rhesus macaque (Macaca mulatta). (23114049)
2012
9
Pituitary tumor apoplexy presenting as infective meningoencephalitis. (21630035)
2012
10
Long-term immunosuppressive therapy with cyclosporine plus prednisolone for necrotizing meningoencephalitis in a Pekingese dog. (22214856)
2012
11
HHV6 meningoencephalitis sequelae in previously healthy children. (22802100)
2012
12
A rare case of survival from primary amebic meningoencephalitis. (22557831)
2012
13
Pituitary apoplexy can mimic acute meningoencephalitis or subarachnoid haemorrhage. (21975129)
2011
14
Tick-borne meningoencephalitis in a 4.5-month-old infant. (20814849)
2011
15
Meningoencephalitis or meningitis in relapsing polychondritis: four case reports and a literature review. (22051026)
2011
16
Thrombotic thrombocytopenic purpura mimicking an acute meningoencephalitis. (21485766)
2011
17
Onset of meningoencephalitis: disseminated candidiasis. (22181574)
2011
18
Meningoencephalitis associated with hepatitis A infection: a case report and review of literature. (20555050)
2010
19
Pathology in practice. Necrotizing pyogranulomatous meningoencephalitis with intralesional fungal hyphae, consistent with Cladophialophora bantiana. (20113240)
2010
20
Primary amoebic meningoencephalitis: first reported case from Rohtak, North India. (20191204)
2009
21
The rationale for integrated childhood meningoencephalitis surveillance: a case study from Cambodia. (19551241)
2009
22
Update on emerging infections: News from the Centers for Disease Control and Prevention. Primary amebic meningoencephalitis-Arizona, Florida, and Texas, 2007. (19708086)
2009
23
A case of Listeria meningoencephalitis complicated by hydrocephalus in an immunocompetent infant. (18463893)
2009
24
Cogan's syndrome: a rare cause of meningoencephalitis. (19491118)
2009
25
Magnetic resonance imaging characteristics of necrotizing meningoencephalitis in Pug dogs. (19645838)
2009
26
Treatment of meningoencephalitis of unknown origin in a dog. (19448257)
2009
27
Necrotizing meningoencephalitis in five Chihuahua dogs. (18487490)
2008
28
Meningoencephalitis associated with human parvovirus B19. (19076847)
2008
29
Meningoencephalitis due to Toscana virus in a French traveler returning from central Italy. (19006512)
2008
30
sICAM-1 intrathecal synthesis and release during the acute phase in children suffering from Coxsackie A9 and S. pneumoniae meningoencephalitis. (18813709)
2008
31
Regression of white matter MRI abnormalities in nonvasculitic autoimmune inflammatory meningoencephalitis following intravenous immunoglobulin. (17389804)
2007
32
Anthrax meningoencephalitis successfully treated. (17661992)
2007
33
Non-suppurative meningoencephalitis of unknown origin in cats and dogs: an immunohistochemical study. (17275833)
2007
34
Virological and immunological characteristics of fatal Epstein-Barr virus mononucleosis in a 17-year-old Caucasian male presenting with meningoencephalitis and hemophagocytic syndrome. (17849323)
2007
35
Ventricular pneumocephalus and septic meningoencephalitis secondary to dorsal rhinotomy and nasal polypectomy in a dog. (16842045)
2006
36
Acute meningoencephalitis caused by adenovirus serotype 26. (16877305)
2006
37
Meningoencephalitis associated with Staphylococcus warneri in a dog. (17004952)
2006
38
Tickborne meningoencephalitis, first case after 19 years in northeastern Germany. (15834983)
2005
39
Pyogranulomatous meningoencephalitis in a goat due to Corynebacterium ulcerans. (15786922)
2005
40
Meningoencephalitis associated with passive immunization of a transgenic murine model of Alzheimer's amyloidosis. (15862291)
2005
41
Pathologic quiz case: headache in an 8-year-old child. Primary amebic meningoencephalitis due to Naegleria fowleri. (14736265)
2004
42
Clinical and neuroinflammatory responses to meningoencephalitis in substance P receptor knockout mice. (12805119)
2003
43
Primary amebic meningoencephalitis--Georgia, 2002. (14534512)
2003
44
Intrathecal humoral immune response in pediatric patients with meningoencephalitis due to Coxsackie B5]. (10363312)
1999
45
From the Centers for Disease Control. Primary amebic meningoencephalitis--North Carolina, 1991. (1640602)
1992
46
Herpes zoster ophthalmicus with delayed cerebral infarction and meningoencephalitis. (3311326)
1987
47
Coxsackievirus B3 producing fatal meningoencephalitis in a patient with X-linked agammaglobulinemia. (6293302)
1983
48
Clinical observations on eosinophilic meningitis and meningoencephalitis caused by Angiostrongylus cantonensis on Taiwan. (1259085)
1976
49
Primary amebic meningoencephalitis. (4620947)
1972
50
Mumps meningoencephalitis with and without parotitis. (18147966)
1949

Variations for Meningoencephalitis

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Expression for genes affiliated with Meningoencephalitis

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Expression patterns in normal tissues for genes affiliated with Meningoencephalitis

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Pathways for genes affiliated with Meningoencephalitis

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Pathways related to Meningoencephalitis according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.5CCL5, APP
2
Show member pathways
9.5CCL5, APP
3
Show member pathways
9.4DARC, CCL5
4
Show member pathways
9.2C5, C9
5
Show member pathways
Immune response Alternative complement pathway60
Immune response Lectin Induced complement pathway60
Immune response Classic complement pathway60
9.2C5, C9
6
Show member pathways
Complement Activation, Classical Pathway37
Complement and Coagulation Cascades37
9.2C5, C9
78.8C5, CCL5, C9
8
Show member pathways
8.7C5, C9, APP
9
Show member pathways
8.1DARC, APP, CCL5, C5
10
Show member pathways
8.1DARC, APP, CCL5, C5

Compounds for genes affiliated with Meningoencephalitis

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Compounds related to Meningoencephalitis according to GeneCards/GeneDecks:

(show all 28)
idCompoundScoreTop Affiliating Genes
1ptca449.8CCL5, CHKB
2cerivastatin50 44 28 1112.8CCL5, CHKB
3propranolol44 28 50 24 1113.8APP, CCL5
4risperidone44 50 28 61 24 1114.8CHKB, APP
5azathioprine44 2 50 1112.7CCL5, CHKB
6lead449.7CHKB, CCL5
7lovastatin44 50 61 28 1113.7CHKB, APP
8gf 109203x44 6110.6CCL5, APP
9egcg449.6CCL5, APP
10anaphylatoxin449.5C5, CCL5
11choline44 24 1111.4APP, CHKB
12endotoxin449.4CCL5, CHKB
13simvastatin44 50 61 28 24 1114.4CCL5, CHKB, APP
14tacrolimus44 50 1111.4CCL5, CHKB, APP
15aspirin44 50 28 2412.3CCL5, CHKB, APP
16methotrexate50 44 1111.3CCL5, CHKB, APP
17epinephrine44 24 1111.3APP, CHKB, CCL5
18cyclosporin a44 28 6111.3APP, CHKB, CCL5
19creatinine449.3APP, CHKB, CCL5
20heparin44 28 24 1112.3CCL5, CHKB, APP
21h2o2449.3CCL5, CHKB, APP
22cholesterol44 28 24 1112.2CCL5, CHKB, APP
23dexamethasone44 50 28 1112.2APP, CHKB, CCL5
24folate449.2CCL5, APP
25vegf449.2CCL5, CHKB, APP
26glutamate449.1CCL5, CHKB, APP
27cysteine449.0CCL5, CHKB, APP
28alanine448.7DARC, APP, CHKB, CCL5

GO Terms for genes affiliated with Meningoencephalitis

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Cellular components related to Meningoencephalitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1membrane attack complexGO:0055798.9C5, C9
2extracellular regionGO:0055768.3C5, CCL5, C9, APP

Biological processes related to Meningoencephalitis according to GeneCards/GeneDecks:

(show all 8)
idNameGO IDScoreTop Affiliating Genes
1chemokine-mediated signaling pathwayGO:0700989.5DARC, CCL5
2complement activation, alternative pathwayGO:0069579.4C5, C9
3regulation of complement activationGO:0304499.4C5, C9
4complement activation, classical pathwayGO:0069589.2C9, C5
5chemotaxisGO:0069359.2C5, CCL5
6cellular calcium ion homeostasisGO:0068749.1C5, CCL5
7inflammatory responseGO:0069548.6C5, CCL5, DARC
8innate immune responseGO:0450878.4C5, C9, APP

Molecular functions related to Meningoencephalitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1chemokine activityGO:0080099.2C5, CCL5

Products for genes affiliated with Meningoencephalitis

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Sources for Meningoencephalitis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet