MD
MCID: MNK001
MIFTS: 81

Menkes Disease (MD) malady

Neuronal diseases, Eye diseases, Skin diseases, Metabolic diseases categories

Summaries for Menkes Disease

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21Genetics Home Reference, 42NIH Rare Diseases, 3CDC, 43NINDS, 63Wikipedia, 46OMIM, 32MalaCards
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Genetics Home Reference:21 Menkes syndrome is a disorder that affects copper levels in the body. It is characterized by sparse, kinky hair; failure to gain weight and grow at the expected rate (failure to thrive); and deterioration of the nervous system. Additional signs and symptoms include weak muscle tone (hypotonia), sagging facial features, seizures, developmental delay, and intellectual disability. Children with Menkes syndrome typically begin to develop symptoms during infancy and often do not live past age 3. Early treatment with copper may improve the prognosis in some affected individuals. In rare cases, symptoms begin later in childhood.

MalaCards: Menkes Disease, also known as copper transport disease, is related to wilson disease and occipital horn syndrome, and has symptoms including intrauterine growth retardation, hypotrichosis/atrichia/atrichiasis/scalp hairlessness and decreased hair pigmentation/hypopigmentation of hair. An important gene associated with Menkes Disease is ATP7A (ATPase, Cu++ transporting, alpha polypeptide), and among its related pathways are Mineral absorption and Platinum Pathway, Pharmacokinetics/Pharmacodynamics. The compounds beta-aminopropionitrile and tetrathiomolybdate have been mentioned in the context of this disorder. Affiliated tissues include brain, liver and skin, and related mouse phenotypes are liver/biliary system and cardiovascular system.

NIH Rare Diseases:42 Menkes disease is a disorder that affects copper levels in the body. it is characterized by sparse, kinky hair; failure to thrive; and deterioration of the nervous system. additional signs and symptoms may be noted. children with menkes syndrome typically begin to develop symptoms during infancy and often do not live past age 3. menkes disease is caused by mutations in the atp7a gene. it is inherited in an x-linked recessive pattern. early treatment with copper may improve the prognosis in some affected individuals. in rare cases, symptoms begin later in childhood. last updated: 3/8/2011

CDC:3 Muscular dystrophies are a group of disorders that result in muscle weakness and a decrease in muscle mass over time. Some muscular dystrophies are not identified until a child is 3 to 6 years of age, but can be diagnosed earlier. To help a child with muscular dystrophy reach his or her full potential, it is very important to get help as early as possible. Acting early can make a real difference!

NINDS:43 Menkes disease is caused by a defective gene named ATPTA that regulates the metabolism of copper in the body. The disease primarily affects male infants. Copper accumulates at abnormally low levels in the liver and brain, but at higher than normal levels in the kidney and intestinal lining. Affected infants may be born prematurely, but appear healthy at birth and develop normally for 6 to 8 weeks. Then symptoms begin, including floppy muscle tone, seizures, and failure to thrive.

Wikipedia:63 Menkes disease (MNK), also called Menkes syndrome, copper transport disease, steely hair disease, kinky... more...

Description from OMIM:46 309400

Aliases & Classifications for Menkes Disease

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Sources:
8Disease Ontology, 9diseasecard, 63Wikipedia, 42NIH Rare Diseases, 21Genetics Home Reference, 43NINDS, 46OMIM, 10DISEASES, 44Novoseek, 48Orphanet, 22GTR, 20GeneTests, 60UMLS, 39NCIt, 56SNOMED-CT, 34MeSH, 26ICD10 via Orphanet, 57SNOMED-CT via Orphanet
See all sources

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Metabolic diseases
Anatomical: Neuronal diseases, Eye diseases, Skin diseases


Characteristics (Orphanet epidemiological data):

48
menkes disease:
Inheritance: X-linked recessive; Age of onset: Neonatal/infancy; Age of death: Before age 5


Aliases & Descriptions:

menkes disease 8 9 63 42 21 43 46 10 44 48
copper transport disease 8 63 42 21
steely hair syndrome 8 63 21 48
menkes syndrome 42 20 21 48
menkea syndrome 63 42 21
mnk 63 21 48
mk 63 21 48
menkes kinky-hair syndrome 8 22
x-linked copper deficiency 21 48
hypocupremia, congenital 63 21
steely hair disease 42 48
kinky hair syndrome 21 48
kinky hair disease 42 48
menkes kinky hair syndrome 60
trichopoliodystrophy 48
md 48


External Ids:

Disease Ontology8 DOID:1838
NCIt39 C75486
MeSH34 D007706
SNOMED-CT56 59178007
OMIM46 309400
ICD10 via Orphanet26 E83.0
SNOMED-CT via Orphanet57 59178007

Related Diseases for Menkes Disease

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Sources:
17GeneCards, 18GeneDecks
See all sources

Diseases related to Menkes Disease via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 220)
idRelated DiseaseScoreTop Affiliating Genes
1wilson disease30.7CP, DNAH8, ATP7B, ATOX1, ATP7A, SOD1
2occipital horn syndrome30.2DBH, ATP7A, LOX
3connective tissue disease30.2LOX, ATP7A, ELN
4swayback30.0CP
5cutis laxa30.0LOX, ELN
6hepatitis30.0CP, DBH
7vascular disease30.0ELN, DNAH8, SOD1, LOX
8prostate cancer29.9PAM, PGK1, MT2A, LOX
9colorectal cancer29.9CP, PGK1, COX5A, LOX
10deficiency anemia29.9COX5A, ATP7A, DBH, PGK1, CP
11neuropathy29.7DNAH8
12amyotrophic lateral sclerosis29.7LOX, CCS, SOD1
13muscular dystrophy10.5
14x-linked disease10.4
15myeloid leukemia10.4
16acute myeloid leukemia10.4
17brain disease10.4
18chromosomal disease10.4
19hair disease10.4
20cytochrome-c oxidase deficiency disease10.3
21acquired kinky hair syndrome10.3
22skin disease10.3
23microcytic anemia10.3
24myelodysplastic syndromes10.3
25bladder disease10.2
26hiatus hernia10.2
27juvenile myelomonocytic leukemia10.2
28aplastic anemia10.2
29childhood leukemia10.2
30bartter disease10.2
31thalamic disease10.2
32bladder diverticulum10.2
33eye disease10.2
34placenta disease10.2
35spinal cord disease10.2
36meckel syndrome10.2
37choroiditis10.1
38aneurysm disease10.1
39choroid disease10.1
40kidney disease10.1
41liver disease10.1
42neurologic diseases10.1
43pili torti10.1
44leukemia10.1
45mckusick-kaufman syndrome10.1
46wolff-parkinson-white syndrome10.1
47clubfoot10.1
48multiple myeloma10.1
49myelofibrosis10.1
50myeloma10.1

Graphical network of the top 20 diseases related to Menkes Disease:



Diseases related to menkes disease

Clinical Features for Menkes Disease

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Sources:
46OMIM, 48Orphanet
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Clinical features from OMIM:

309400

Clinical synopsis from OMIM:

309400

Symptoms:

48 (show all 57)
  • intrauterine growth retardation
  • hypotrichosis/atrichia/atrichiasis/scalp hairlessness
  • decreased hair pigmentation/hypopigmentation of hair
  • hematomas
  • expressionless face/amimia
  • abnormal scarring/cheloids/hypertrophic scars
  • x-linked recessive inheritance
  • osteomyelitis/osteitis/periostitis/spondylodisciitis
  • gastrointestinal bleeding/hemorrhage/hematemesis/melena/rectorrhagia
  • arterial aneurism (excluding aorta)
  • varices/varicous veins/venous insufficiency
  • intracranial/cerebral/meningeal hemorrhage
  • high vaulted/narrow palate
  • tarsal anomaly/fusion/synostosis
  • enlargment of jaw/large jaw
  • woolly/frizzy hair
  • hyperelastic skin/cutaneous hyperlaxity
  • bladder/vesical diverticulum
  • carotid artery anomalies
  • arterial stenosis/occlusion
  • sepsis severe/septicemia
  • periarticular tissue anomaly/extraarticular calcifications
  • thick skin/pachydermia/orange skin
  • prominent occiput/occipital bossing
  • bowed diaphysis/diaphyses/long bones
  • psychic/behavioural troubles
  • inguinal/inguinoscrotal/crural hernia
  • osteoporosis/osteopenia/demineralisation/osteomalacia/rickets
  • muscle weakness/flaccidity
  • psychic/psychomotor regression/dementia/intellectual decline
  • hypotonia
  • chorea/athetosis/choreoathetosis/choreic syndrome
  • hypothermia
  • feeding disorder/dysphagia/swallowing/sucking disorder/esophageal dyskinesia
  • intellectual deficit/mental/psychomotor retardation/learning disability
  • seizures/epilepsy/absences/spasms/status epilepticus
  • hypertonia/spasticity/rigidity/stiffness
  • motor deficit/trouble
  • nausea/vomiting/regurgitation/merycism/hyperemesis
  • umbilical hernia
  • malabsorption/chronic diarrhea/steatorrhea
  • mutiple fractures/bone fragility
  • wormian bones
  • hyperextensible joints/articular hyperlaxity
  • narrow rib cage/thorax
  • herniae
  • metaphyseal anomaly
  • dry/squaly skin/exfoliation
  • exostoses
  • micrognathia/retrognathia/micrognathism/retrognathism
  • hepatitis/icterus/cholestasis
  • hypoglycemia
  • broad cheeks/cherub-like/cherubin face
  • asthenia/fatigue/weakness
  • absent/hypotonic/flaccid abdominal wall muscles
  • microcephaly
  • pectus excavatum

Drugs & Therapeutics for Menkes Disease

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
See all sources

Approved drugs:

Search CenterWatch for Menkes Disease

Drug clinical trials:

Search ClinicalTrials for Menkes Disease

Search NIH Clinical Center for Menkes Disease

Search CenterWatch for Menkes Disease

Genetic Tests for Menkes Disease

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Sources:
20GeneTests, 22GTR
See all sources

Genetic tests related to Menkes Disease:

id Genetic test Affiliating Genes
1 Menkes Disease20 ATP7A
2 Menkes Kinky-Hair Syndrome22

Anatomical Context for Menkes Disease

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32MalaCards
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MalaCards organs/tissues related to Menkes Disease:

32
Brain, Liver, Skin, Kidney, Bone, Eye, Cortex, Temporal lobe, Cerebellum, Placenta, Heart, Spinal cord, Thalamus

Animal Models for Menkes Disease or affiliated genes

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36MGI
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MGI Mouse Phenotypes related to Menkes Disease:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:000537010.2MT2A, ATOX1
2MP:00053859.1LOX, SOD1, ATP7A, ATOX1, MT2A, DBH
3MP:00053768.7ELN, LOX, COX17, CCS, SOD1, MFI2

Publications for Menkes Disease

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Sources:
50PubMed
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Articles related to Menkes Disease:

(show top 50)    (show all 387)
idTitleAuthorsYear
1
L-threo-dihydroxyphenylserine corrects neurochemical abnormalities in a Menkes disease mouse model. (23224983)
2013
2
Effects of disulfiram treatment in patients with Menkes disease and occipital horn syndrome. (22575542)
2012
3
Increased frequency of congenital heart defects in Menkes disease. (22134099)
2012
4
Kinky hair, kinky vessels, and bladder diverticula in Menkes disease. (20412396)
2011
5
A Drosophila model of Menkes disease reveals a role for DmATP7 in copper absorption and neurodevelopment. (20038716)
2010
6
Unusual magnetic resonance imaging features in Menkes disease. (18243619)
2008
7
Multiple bladder diverticula in Menkes disease. (18210098)
2008
8
Internal jugular phlebectasia in Menkes disease. (17482283)
2007
9
From gene to disease; Menkes disease: copper deficiency due to an ATP7A-gene defect]. (17987894)
2007
10
Phenotypic diversity of Menkes disease in mottled mice is associated with defects in localisation and trafficking of the ATP7A protein. (17483305)
2007
11
The effects of copper-histidine therapy on brain metabolism in a patient with Menkes disease: a proton magnetic resonance spectroscopic study. (15862194)
2005
12
Downregulation of myelination, energy, and translational genes in Menkes disease brain. (15923132)
2005
13
Lumbar and iliac artery aneurysms in Menkes' disease: endovascular cover stent treatment of the lumbar artery aneurysm. (15891878)
2005
14
Renal function in patients with Menkes disease. (12607531)
2003
15
"From sheep to babe"--Menkes disease. (14672268)
2003
16
Treatment of Menkes disease with parenteral copper histidine. (11867850)
2002
17
X-linked recessive Menkes disease: carrier detection in the case of a partial gene deletion. (12485191)
2002
18
Abnormality of vascular elastic fibers in the macular mouse and a patient with Menkes' disease: ultrastructural and immunohistochemical study. (12111404)
2002
19
Identification of four novel mutations in classical Menkes disease and successful prenatal DNA diagnosis. (11350187)
2001
20
Copper in disorders with neurological symptoms: Alzheimer's, Menkes, and Wilson diseases. (11470313)
2001
21
Menkes kinky hair disease: an unusual case. (10872109)
2000
22
Structural basis for copper transfer by the metallochaperone for the Menkes/Wilson disease proteins. (10966647)
2000
23
Cerebral infarction in Menkes' disease. (11118799)
2000
24
The cell biology of the Menkes disease protein. (10079815)
1999
25
Mutation spectrum of ATP7A, the gene defective in Menkes disease. (10079817)
1999
26
RESPONSIVE-TO-ANTAGONIST1, a Menkes/Wilson disease-related copper transporter, is required for ethylene signaling in Arabidopsis. (10319818)
1999
27
Mutation analysis provides additional proof that mottled is the mouse homologue of Menkes' disease. (9147645)
1997
28
The mottled mouse as a model for human Menkes disease: identification of mutations in the Atp7a gene. (9158160)
1997
29
Characterization of the exon structure of the Menkes disease gene using vectorette PCR. (7607665)
1995
30
Menkes disease and occipital horn syndrome. (7583733)
1995
31
Molecular structure of the Menkes disease gene (ATP7A). (7490081)
1995
32
Electrophysiological and 99mTc-HMPAO-SPECT studies in Menkes disease. (7943608)
1994
33
Are X-linked cutis laxa and Menkes disease allelic? (8490656)
1993
34
Isolation of a partial candidate gene for Menkes disease by positional cloning. (8490647)
1993
35
Isolation of a candidate gene for Menkes disease that encodes a potential heavy metal binding protein. (8490646)
1993
36
Menkes disease: an X-linked neurological disorder of the copper metabolism. (1341968)
1992
37
Metallothionein in Menkes' disease: induction in cultured muscle cells. (2089140)
1990
38
Markedly reduced activity of lysyl oxidase in skin and aorta from a patient with Menkes' disease showing unusually severe connective tissue manifestations. (1975662)
1990
39
Menkes disease. (3225036)
1988
40
Biochemical study on the brain of the macular mutant mouse as a model of Menkes' kinky hair disease. (2453126)
1988
41
Menkes disease: a Golgi and electron microscopic study of the cerebellar cortex. (3390973)
1988
42
Metallothionein gene regulation in Menkes' disease. (3530953)
1986
43
Menkes' kinky hair disease. II. A clinicopathological report of three cases. (7091568)
1982
44
Diagnosis of Menkes' disease from 67Cu uptake by cultured cells. (7460309)
1981
45
Synthesis of a metallothionein-like protein in cultured human skin fibroblasts: relation to abnormal copper distribution in Menkes' disease. (7217218)
1981
46
Abnormal copper-thionein synthesis and impaired copper utilization in mutated brindled mice: model for Menkes' disease. (7188777)
1980
47
Copper metabolism in Menkes disease. (471578)
1979
48
Menkes disease: a biochemical abnormality in cultured human fibroblasts. (1061160)
1976
49
Menkes kinky hair disease. A defect in metallothionein metabolism? (4458824)
1974
50
Menkes' steely-hair (kinky-hair) disease. (4123446)
1973

Genetic Variations for Menkes Disease

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Sources:
62UniProtKB/Swiss-Prot
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Genetic disease variations for Menkes Disease:

62 (show all 33)
id Symbol AA change Variation ID SNP ID
1ATP7Ap.Ala629ProVAR_000699
2ATP7Ap.Gly727ArgVAR_000700
3ATP7Ap.Leu1006ProVAR_000701
4ATP7Ap.Gly1019AspVAR_000702
5ATP7Ap.Leu873ArgVAR_010001
6ATP7Ap.Gly876GluVAR_010002
7ATP7Ap.Cys1000ArgVAR_010003
8ATP7Ap.Gly1300GluVAR_010004
9ATP7Ap.Gly1302ArgVAR_010005
10ATP7Ap.Gly1302ValVAR_010006
11ATP7Ap.Asp1305AlaVAR_010007
12ATP7Ap.Ala1362ValVAR_010008
13ATP7Ap.Leu706ArgVAR_023261
14ATP7Ap.Arg844HisVAR_023262
15ATP7Ap.Gly853ArgVAR_023263
16ATP7Ap.Gly860ValVAR_023264
17ATP7Ap.Gly876ArgVAR_023265
18ATP7Ap.Gln924ArgVAR_023266
19ATP7Ap.Ala1007ValVAR_023267
20ATP7Ap.Gly1015AspVAR_023268
21ATP7Ap.Asp1044GlyVAR_023269
22ATP7Ap.Leu1100ProVAR_023270
23ATP7Ap.Gly1118AspVAR_023271
24ATP7Ap.Gly1255ArgVAR_023272
25ATP7Ap.Lys1282GluVAR_023273
26ATP7Ap.Asn1304LysVAR_023274
27ATP7Ap.Gly1315ArgVAR_023275
28ATP7Ap.Ala1325ValVAR_023276
29ATP7Ap.Ser1344ArgVAR_023277
30ATP7Ap.Ile1345PheVAR_023278
31ATP7Ap.Gly1369ArgVAR_023279
32ATP7Ap.Ser1397PheVAR_023280
33ATP7Ap.Thr1048IleVAR_068831

Expression for genes affiliated with Menkes Disease

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Menkes Disease

Search GEO for disease gene expression data for Menkes Disease.

Pathways for genes affiliated with Menkes Disease

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29KEGG, 49PharmGKB
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Pathways related to Menkes Disease according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
110.1MT2A, ATOX1, ATP7A
210.0MT2A, ATP7B, ATP7A, SOD1

Compounds for genes affiliated with Menkes Disease

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Sources:
44Novoseek, 49PharmGKB, 28IUPHAR, 11DrugBank, 24HMDB, 59Tocris Bioscience
See all sources

Compounds related to Menkes Disease according to GeneCards/GeneDecks:

(show top 50)    (show all 67)
idCompoundScoreTop Affiliating Genes
1beta-aminopropionitrile4410.6ELN, LOX
2tetrathiomolybdate4410.6ATP7B, CP
3dmpo-oh4410.6SOD1, CP
4alpha-aminoadipic semialdehyde4410.6LOX, ELN
5randox4410.6SOD1, CP
6desmosine4410.6LOX, ELN
7plastocyanin4410.5ATOX1, CP
8peptidylglycine4410.5CP, PAM, DBH
9d penicillamine4410.5LOX, CP, ELN
10dexamethasone44 49 28 1113.5PAM, DBH, LOX
11copper(i)4410.5ATP7A, ATOX1, ATP7B
12acyl phosphate4410.5ATP7A, ATP7B, DNAH8
13copper histidine4410.5COX5A, ATP7A, CP
14bioflavonoids4410.5SOD1, DNAH8
15zinc superoxide4410.5CCS, SOD1
16proadifen4410.5LOX, COX5A
17hemocyanin4410.5ATOX1, DBH, PAM
18deferoxamine44 1111.5CP, MFI2, SOD1
19diethyl dithiocarbamate4410.5COX5A, SOD1, DBH
20hypoxanthine44 11 2412.4CP, PGK1, SOD1
21oxaliplatin44 49 1112.4ATP7B, ATP7A, SOD1
22ndga4410.4LOX, COX5A, SOD1
23amine4410.4ELN, PAM, DBH, LOX
24aa8614410.3LOX, COX5A
25dmpo4410.3SOD1, CP
26sodium azide4410.3COX5A, SOD1, DNAH8, CP
27betacarotene4410.3ELN, CP, SOD1
28hydroxylysine4410.3LOX, ELN
29suprofen44 1111.2CP, SOD1
30salicylic acid44 2811.2LOX, COX5A, DNAH8
31n acetylcysteine4410.2LOX, COX5A, SOD1, MT2A, ELN
32sodium nitroprusside4410.2ELN, CP, DNAH8, SOD1, COX5A
33lysine4410.2LOX, ATOX1, DBH, PGK1, ELN
34cisplatin44 49 59 1113.2LOX, SOD1, ATP7A, ATP7B, MT2A
35aspartate4410.1ATP7A, ATP7B, DNAH8, CP, ELN
36indomethacin44 59 28 1113.1LOX, COX5A, SOD1, DNAH8, CP, ELN
37carboplatin44 49 1112.0SOD1, ATP7A, ATP7B
38lactate4410.0LOX, COX5A, SOD1, DBH, PGK1, CP
39theophylline44 28 11 2413.0ELN, DNAH8, COX5A
40creatinine4410.0COX5A, SOD1, DNAH8, CP, ELN
41iron44 2411.0COX5A, SOD1, MFI2, ATOX1, ATP7B, DBH
42ascorbic acid44 2410.9LOX, COX5A, SOD1, DBH, PGK1, PAM
43glutamate449.9COX5A, SOD1, DNAH8, DBH, CP, ELN
44h2o2449.9LOX, COX5A, SOD1, MT2A, DBH, PGK1
45oxygen44 2410.8LOX, COX5A, CCS, MFI2, ATOX1, MT2A
46zinc44 2410.7CCS, SOD1, MFI2, ATP7A, ATOX1, ATP7B
47histidine449.7PAM, DBH, ATOX1, LOX
48cysteine449.4LOX, COX5A, CCS, SOD1, ATOX1, ATP7B
49superoxide44 2410.3PGK1, DBH, MT2A, ATP7B, ATOX1, ATP7A
50copper44 2410.2ELN, LOX, CP, PAM, DBH, MT2A

GO Terms for genes affiliated with Menkes Disease

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16Gene Ontology
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Cellular components related to Menkes Disease according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1trans-Golgi networkGO:00580210.1PAM, ATP7B, ATP7A
2extracellular regionGO:0055769.3ELN, LOX, SOD1, MFI2, DBH, PAM

Biological processes related to Menkes Disease according to GeneCards/GeneDecks:

(show all 13)
idNameGO IDScoreTop Affiliating Genes
1copper ion importGO:01567710.4ATP7A, ATP7B
2intracellular copper ion transportGO:01568010.4CCS, ATP7B
3norepinephrine biosynthetic processGO:04242110.4ATP7A, DBH
4response to copper ionGO:04668810.3SOD1, ATP7B, PAM
5removal of superoxide radicalsGO:01943010.3ATP7A, SOD1, CCS
6elastic fiber assemblyGO:04825110.3ATP7A, LOX
7blood vessel remodelingGO:00197410.3ELN, DBH, ATP7A
8positive regulation of oxidoreductase activityGO:05135310.2CCS, ATP7A
9cellular copper ion homeostasisGO:00687810.2ATP7A, ATOX1, ATP7B, MT2A
10superoxide metabolic processGO:00680110.2SOD1, CCS
11copper ion transportGO:00682510.1CP, ATP7B, ATOX1, ATP7A, COX17
12cellular iron ion homeostasisGO:00687910.0CP, MFI2, SOD1
13locomotory behaviorGO:0076269.8DBH, ATP7A, SOD1

Molecular functions related to Menkes Disease according to GeneCards/GeneDecks:

(show all 7)
idNameGO IDScoreTop Affiliating Genes
1superoxide dismutase copper chaperone activityGO:01653210.3CCS, ATP7A
2copper-exporting ATPase activityGO:00400810.3ATP7A, ATP7B
3copper ion transmembrane transporter activityGO:00537510.2ATP7A, CCS
4copper chaperone activityGO:01653110.2COX17, ATOX1
5copper-dependent protein bindingGO:03276710.1ATOX1, ATP7A
6superoxide dismutase activityGO:0047849.9SOD1, CCS
7copper ion bindingGO:0055079.3CP, LOX, COX17, CCS, SOD1, ATP7A

Products for genes affiliated with Menkes Disease

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Menkes Disease

About this section
3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet