Mental Retardation, Autosomal Dominant 2 malady

MalaCards: Mental Retardation, Autosomal Dominant 2, also known as mental retardation, is related to mental retardation syndrome and microcephaly. An important gene associated with Mental Retardation, Autosomal Dominant 2 is DOCK8 (dedicator of cytokinesis 8). The drugs buspirone hydrochloride and buspirone have been mentioned in the context of this disorder.

mental retardation, autosomal dominant 2 33 mental retardation 43

Disease types for mental retardation, autosomal dominant 3 family:

mental retardation, autosomal dominant 1	mental retardation, autosomal dominant 13
mental retardation, autosomal dominant 5	mental retardation, autosomal dominant 6
mental retardation, autosomal dominant 9	mental retardation, autosomal dominant 4
mental retardation, autosomal dominant 2

Diseases related to mental retardation, autosomal dominant 2 by text searches and GeneDecks gene sharing:

(show top 50)    (show all 656)

id	Related Disease	Score	Top Affiliating Genes
1	mental retardation syndrome	10.4
2	microcephaly	9.4
3	fragile x syndrome	9.2
4	wagr syndrome	9.2
5	renpenning syndrome 1	9.1
6	mental retardation, autosomal dominant 5	8.8
7	mental retardation, autosomal dominant 1	8.8
8	mental retardation epilepsy	8.7
9	alpha-thalassemia/mental retardation syndrome	8.6
10	mental retardation, x-linked, nonspecific	8.6
11	x-linked mental retardation 9	8.6
12	x-linked mental retardation with epilepsy	8.5
13	mental retardation, autosomal dominant 13	8.4
14	alpha thalassemia	8.4
15	short stature	8.4
16	thalassemia	8.4
17	x-linked mental retardation 58	8.4
18	x-linked mental retardation 63	8.4
19	x-linked mental retardation 89	8.4
20	x-linked mental retardation 30	8.3
21	x-linked mental retardation 54	8.3
22	lubs x-linked mental retardation syndrome	8.3
23	mental retardation x-linked with cerebellar hypoplasia and distinctive facial appearance	8.3
24	coffin-lowry syndrome	8.1
25	hypogonadism	8.1
26	mental retardation, x-linked	8.1
27	mowat-wilson syndrome	8.1
28	siderius x-linked mental retardation syndrome	8.1
29	x-linked mental retardation 90	7.9
30	alpha-thalassemia x-linked intellectual disability syndrome	7.9
31	alopecia contractures dwarfism mental retardation	7.9
32	birk-barel syndrome	7.9
33	down syndrome	7.9
34	mental retardation x-linked syndromic 7	7.9
35	mental retardation-hypotonic facies syndrome, x-linked	7.9
36	partington x-linked mental retardation syndrome	7.9
37	rett syndrome	7.9
38	mental retardation, autosomal dominant 9	7.9
39	mental retardation, autosomal dominant 3	7.9
40	mental retardation, autosomal dominant 4	7.9
41	mental retardation, autosomal dominant 6	7.9
42	x-linked mental retardation 59	7.7
43	abidi x-linked mental retardation syndrome	7.7
44	x-linked mental retardation 72	7.7
45	aniridia	7.7
46	x-linked mental retardation 88	7.7
47	brachydactyly-mental retardation syndrome	7.7
48	x-linked mental retardation 93	7.7
49	dysequilibrium syndrome	7.7
50	x-linked mental retardation 94	7.7

Approved drugs:

Drug clinical trials:

Inferred drug relations via UMLS/NDF-RT:

^43 28 buspirone, buspirone hydrochloride

Genes related to mental retardation, autosomal dominant 2 according to GeneCards:

id	Symbol	Description	Score	GeneCards Section Context
1	DOCK8	dedicator of cytokinesis 8	11.1	Disorders