Aliases & Classifications for Mercury Poisoning

MalaCards integrated aliases for Mercury Poisoning:

Name: Mercury Poisoning 50 56
Mercury Intoxication 56
Mercury Toxicity 50
Mercurialism 56
Hydrargyria 56

Characteristics:

Orphanet epidemiological data:

56
mercury poisoning
Inheritance: Not applicable; Prevalence: 1-9/100000 (Europe); Age of onset: All ages; Age of death: any age;

Classifications:



Summaries for Mercury Poisoning

NIH Rare Diseases : 50 mercury poisoning is a condition that occurs in people who are exposed to toxic levels of the element, mercury. there are three different forms of mercury that can cause health problems:elemental mercury (also known as liquid mercury or quicksilver) can be found in glass thermometers, electrical switches, dental fillings and fluorescent light bulbs. this form of mercury is generally only harmful when small droplets become airborne and are inhaled. if this occurs, signs and symptoms of poisoning may include metallic taste, vomiting, difficulty breathing, coughing, and/or swollen, bleeding gums. in severe cases, long-term brain damage, permanent lung damage and even death may occur. inorganic mercury is found in batteries, chemistry labs, and some disinfectants. this form of mercury is harmful when swallowed. signs and symptoms of inorganic mercury poisoning vary based on the amount consumed, but may include burning in the stomach and throat; vomiting; and/or bloody diarrhea. inorganic mercury can also affect the kidneys and brain if it enters the blood stream. organic mercury can be found in fish. some organisms convert fumes from burning coal into organic mercury. this form of mercury is harmful if inhaled, eaten, or placed on the skin for long periods of time. long-term exposure to organic mercury may result in skin numbness or pain; tremor; inability to walk well; blindness; double vision; memory problems; seizures; or even death. treatment is generally supportive and based on the signs and symptoms present in each person. medications called chelators, which remove mercury and heavy metals from the body, are generally prescribed. last updated: 2/5/2016

MalaCards based summary : Mercury Poisoning, also known as mercury intoxication, is related to hepatitis b and infantile mercury poisoning, and has symptoms including hypertension, seizures and confusion. An important gene associated with Mercury Poisoning is B2M (Beta-2-Microglobulin), and among its related pathways/superpathways are Formation of Fibrin Clot (Clotting Cascade) and Immune response IFN alpha/beta signaling pathway. The drug Chelating Agents has been mentioned in the context of this disorder. Affiliated tissues include kidney, skin and brain, and related phenotypes are Negative genetic interaction between PTTG1-/- and PTTG1+/+ and cellular

Wikipedia : 72 Mercury poisoning is a type of metal poisoning due to mercury exposure. Symptoms depend upon the type,... more...

Related Diseases for Mercury Poisoning

Diseases in the Mercury Poisoning family:

Infantile Mercury Poisoning

Diseases related to Mercury Poisoning via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 50)
id Related Disease Score Top Affiliating Genes
1 hepatitis b 29.5 B2M IL18
2 infantile mercury poisoning 12.0
3 erythromelalgia 11.0
4 steatorrhea 10.1 B2M IL18
5 idiopathic juvenile osteoporosis 10.1 B2M IL18
6 omphalocele 10.1
7 purpura fulminans 10.1 IL13 IL18
8 fungal gastritis 10.1 IL13 IL18
9 acute liver failure 10.0 B2M IL18
10 hepatitis 10.0
11 nephrotic syndrome 10.0
12 peritonitis 10.0
13 ragweed sensitivity 9.9 IL13 IL18
14 neuronitis 9.9
15 immunodeficiency 32b, monocyte and dendritic cell deficiency, autosomal recessive 9.9 PLAT THBD
16 elizabethkingia anophelis infection 9.9 PLAT THBD
17 lymphatic system cancer 9.9 PLAT THBD
18 dyskeratosis congenita autosomal recessive 9.8 PLAT THBD
19 fiedler's myocarditis 9.8 PLAT THBD
20 haemophilus meningitis 9.8 PLAT THBD
21 thrombophilia due to activated protein c resistance 9.8 PLAT THBD
22 brill-zinsser disease 9.8 PLAT THBD
23 pregnancy loss, recurrent 2 9.7 PLAT THBD
24 pheochromocytoma 9.7
25 myocardial infarction 9.7
26 creutzfeldt-jakob disease 9.7
27 pemphigus foliaceus 9.7
28 renal tubular acidosis 9.7
29 thrombocytopenia 9.7
30 brucellosis 9.7
31 toxic shock syndrome 9.7
32 vaginitis 9.7
33 anuria 9.7
34 hyperthyroidism 9.7
35 pemphigus 9.7
36 intracranial hypertension 9.7
37 periostitis 9.7
38 birth defects 9.7
39 heavy metal poisoning 9.7
40 myoclonus 9.7
41 mixed germ cell-sex cord neoplasm 9.7 PLAT THBD
42 goodpasture syndrome 9.7 IL18 THBD
43 angina pectoris 9.7 PLAT THBD
44 epithelioid type angiomyolipoma 9.6 IL13 IL18
45 bone remodeling disease 9.6 PLAT THBD
46 hepatic adenoma, somatic 9.4 B2M IL18 THBD
47 pseudohypoaldosteronism, type iid 9.4 IL13 IL18
48 malaria 9.3 IL13 IL18 THBD
49 necatoriasis 9.2 IL18 PLAT THBD
50 mesomelia 8.3 B2M IL13 IL18 PLAT THBD

Graphical network of the top 20 diseases related to Mercury Poisoning:



Diseases related to Mercury Poisoning

Symptoms & Phenotypes for Mercury Poisoning

Human phenotypes related to Mercury Poisoning:

56 32 (show all 21)
id Description HPO Frequency Orphanet Frequency HPO Source Accession
1 hypertension 56 32 frequent (33%) Frequent (79-30%) HP:0000822
2 seizures 56 32 frequent (33%) Frequent (79-30%) HP:0001250
3 confusion 56 32 frequent (33%) Frequent (79-30%) HP:0001289
4 dystonia 56 32 frequent (33%) Frequent (79-30%) HP:0001332
5 tremor 56 32 frequent (33%) Frequent (79-30%) HP:0001337
6 tachycardia 56 32 frequent (33%) Frequent (79-30%) HP:0001649
7 acute kidney injury 56 32 frequent (33%) Frequent (79-30%) HP:0001919
8 nausea 56 32 frequent (33%) Frequent (79-30%) HP:0002018
9 anorexia 56 32 frequent (33%) Frequent (79-30%) HP:0002039
10 respiratory distress 56 32 frequent (33%) Frequent (79-30%) HP:0002098
11 abnormality of the cerebral white matter 56 32 frequent (33%) Frequent (79-30%) HP:0002500
12 episodic vomiting 56 32 frequent (33%) Frequent (79-30%) HP:0002572
13 episodic abdominal pain 56 32 frequent (33%) Frequent (79-30%) HP:0002574
14 hypotension 56 32 frequent (33%) Frequent (79-30%) HP:0002615
15 respiratory failure 56 32 frequent (33%) Frequent (79-30%) HP:0002878
16 hypokalemia 56 32 frequent (33%) Frequent (79-30%) HP:0002900
17 generalized muscle weakness 56 32 frequent (33%) Frequent (79-30%) HP:0003324
18 interstitial pneumonitis 56 32 frequent (33%) Frequent (79-30%) HP:0006515
19 loss of consciousness 56 32 frequent (33%) Frequent (79-30%) HP:0007185
20 insomnia 56 32 frequent (33%) Frequent (79-30%) HP:0100785
21 dyspnea 56 Frequent (79-30%)

GenomeRNAi Phenotypes related to Mercury Poisoning according to GeneCards Suite gene sharing:

26
id Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Negative genetic interaction between PTTG1-/- and PTTG1+/+ GR00255-A-4 8.8 B2M IL13 THBD

MGI Mouse Phenotypes related to Mercury Poisoning:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 9.85 B2M IL13 IL18 PLAT THBD
2 digestive/alimentary MP:0005381 9.83 B2M IL13 IL18 PLAT THBD
3 growth/size/body region MP:0005378 9.8 B2M IL13 IL18 PLAT THBD
4 hematopoietic system MP:0005397 9.77 B2M IL13 IL18 PLAT THBD
5 homeostasis/metabolism MP:0005376 9.72 B2M IL13 IL18 PLAT THBD
6 immune system MP:0005387 9.65 B2M IL13 IL18 PLAT THBD
7 integument MP:0010771 9.46 B2M IL13 IL18 THBD
8 mortality/aging MP:0010768 9.35 B2M IL13 IL18 PLAT THBD
9 reproductive system MP:0005389 8.92 B2M IL13 PLAT THBD

Drugs & Therapeutics for Mercury Poisoning

Drugs for Mercury Poisoning (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


id Name Status Phase Clinical Trials Cas Number PubChem Id
1 Chelating Agents Phase 2

Interventional clinical trials:


id Name Status NCT ID Phase Drugs
1 Pilot Proof of Concept Study of NBMI Treatment of Mercury Intoxication Completed NCT02486289 Phase 2 Emeramide;Placebo
2 Environmental Contaminants and Infant Development Completed NCT00013858

Search NIH Clinical Center for Mercury Poisoning

Genetic Tests for Mercury Poisoning

Anatomical Context for Mercury Poisoning

MalaCards organs/tissues related to Mercury Poisoning:

39
Kidney, Skin, Brain, Lung, Liver, Skeletal Muscle, Cortex

Publications for Mercury Poisoning

Articles related to Mercury Poisoning:

(show top 50) (show all 341)
id Title Authors Year
1
Cases of acute mercury poisoning by mercury vapor exposure during the demolition of a fluorescent lamp factory. ( 28649389 )
2017
2
The interwoven history of mercury poisoning in Ontario and Japan. ( 28385869 )
2017
3
Assessment and management of elemental mercury poisoning-a case report. ( 28174636 )
2017
4
Mercury poisoning in the Grassy Narrows First Nation: history not completed. ( 28584045 )
2017
5
Mercury Poisoning at a Home Day Care Center - Hillsborough County, Florida, 2015. ( 28472024 )
2017
6
Acute Mercury Poisoning in a Group of School Children. ( 27977534 )
2016
7
The interwoven history of mercury poisoning in Ontario and Japan. ( 27920011 )
2016
8
Acute mercury poisoning from occult ritual use. ( 28913479 )
2016
9
Saint Ioannis Lampadistis, the first possible case of blindness due to organic mercury poisoning in history. ( 27686425 )
2016
10
Occupational Metallic Mercury Poisoning in Gilders. ( 27112720 )
2016
11
Mercury poisoning caused by Chinese folk prescription (CFP): A case report and analysis of both CFP and quackery. ( 27858849 )
2016
12
Mercury Poisoning in Operational Settings among Gilders. ( 27651086 )
2016
13
Mercury poisoning presenting as sporadic creutzfeldt-jakob disease: a case report. ( 25775335 )
2015
14
Mercury poisoning in two 13-year-old twin sisters. ( 26109979 )
2015
15
Notes from the Field: Acute Mercury Poisoning After Home Gold and Silver Smelting--Iowa, 2014. ( 26678598 )
2015
16
Mercury Poisoning as a Cause of Intracranial Hypertension. ( 25122110 )
2014
17
Subacute motor neuron hyperexcitability with mercury poisoning: a case series and literature review. ( 25227723 )
2014
18
Mercury poisoning: a case of a complex neuropsychiatric illness. ( 25756767 )
2014
19
Mercury poisoning dentistry: high-level indoor air mercury contamination at selected dental sites. ( 24552960 )
2014
20
Acute mercury poisoning presenting as fever of unknown origin in an adult woman: a case report. ( 25084829 )
2014
21
Current approaches of the management of mercury poisoning: need of the hour. ( 24888360 )
2014
22
The role of chelation in the treatment of arsenic and mercury poisoning. ( 24178900 )
2013
23
Ophthalmic findings in acute mercury poisoning in adults: A case series study. ( 23524881 )
2013
24
Mercury poisoning from home gold amalgam extraction. ( 23879513 )
2013
25
Acute mercury poisoning among children in two provinces of Turkey. ( 23411638 )
2013
26
Public health department response to mercury poisoning: the importance of biomarkers and risks and benefits analysis for chelation therapy. ( 24197663 )
2013
27
Metal mercury poisoning in two boys initially treated for brucellosis in Mashhad, Iran. ( 21803782 )
2012
28
Chronic methyl mercury poisoning may trigger endemic pemphigus foliaceus "fogo selvagem". ( 22000710 )
2012
29
Assessment and management of mercury poisoning with an unusual abdominal x-ray! ( 23087291 )
2012
30
Mercury poisoning: a diagnostic challenge. ( 23128656 )
2012
31
Elemental mercury poisoning presenting as hypertension in a young child. ( 22863825 )
2012
32
Not all that glitters: mercury poisoning in Colombia. ( 22509527 )
2012
33
Effects of selenite and chelating agents on mammalian thioredoxin reductase inhibited by mercury: implications for treatment of mercury poisoning. ( 20810785 )
2011
34
Pediatric mercury poisoning, brain MRI, and white matter hyperintensities. ( 21340488 )
2011
35
Re: Care of patients who are worried about mercury poisoning from dental fillings. ( 21737774 )
2011
36
Inorganic mercury poisoning associated with skin-lightening cosmetic products. ( 22070559 )
2011
37
Mercury poisoning in a free-living northern river otter (Lontra canadensis). ( 20688719 )
2010
38
Elemental mercury poisoning caused by subcutaneous and intravenous injection: An unusual self-injury. ( 20607031 )
2010
39
Care of patients who are worried about mercury poisoning from dental fillings. ( 21057078 )
2010
40
Acute mercury poisoning: a case report. ( 20302609 )
2010
41
Images in radiology. An element of surprise. Mercury poisoning. ( 20920692 )
2010
42
Chronic mercury poisoning: Report of two siblings. ( 20808663 )
2010
43
Fatal mercury poisoning and chelating agents. ( 20537473 )
2010
44
Fish faddism causing low-level mercury poisoning in the Caribbean: two case reports. ( 20126317 )
2009
45
Mercury poisoning in a German shepherd dog. ( 19820261 )
2009
46
Mercury poisoning: a rare but treatable cause of failure to thrive and developmental regression in an infant. ( 19197099 )
2009
47
Minamata disease revisited: an update on the acute and chronic manifestations of methyl mercury poisoning. ( 17681548 )
2007
48
Elemental mercury poisoning probably causes cortical myoclonus. ( 17708573 )
2007
49
A Child with elemental mercury poisoning and unusual brain MRI findings. ( 16496500 )
2006
50
I love canned tuna, but I've heard that eating too much increases your risk of mercury poisoning. Is this true? ( 16489293 )
2006

Variations for Mercury Poisoning

Expression for Mercury Poisoning

Search GEO for disease gene expression data for Mercury Poisoning.

Pathways for Mercury Poisoning

GO Terms for Mercury Poisoning

Cellular components related to Mercury Poisoning according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.46 B2M IL13 IL18 PLAT
2 cell surface GO:0009986 9.13 B2M PLAT THBD
3 extracellular space GO:0005615 9.02 B2M IL13 IL18 PLAT THBD

Biological processes related to Mercury Poisoning according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 immune response GO:0006955 9.33 B2M IL13 IL18
2 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 8.65 IL18
3 positive regulation of smooth muscle cell proliferation GO:0048661 8.62 IL13 IL18

Sources for Mercury Poisoning

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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