MCID: MSN001
MIFTS: 46

Mesangial Proliferative Glomerulonephritis malady

Rare diseases category

Aliases & Classifications for Mesangial Proliferative Glomerulonephritis

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Mesangial Proliferative Glomerulonephritis, Aliases & Descriptions:

Name: Mesangial Proliferative Glomerulonephritis 9 41 60
Glomerulonephritis - Mesangial Proliferative 41
 
Glomerulonephritis Mesangial Proliferative 43
Mesangial Proliferative Gn 41


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases


External Ids:

Disease Ontology9 DOID:4783
SNOMED-CT55 35546006
NCIt38 C35445

Summaries for Mesangial Proliferative Glomerulonephritis

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Wikipedia:63 Mesangial proliferative glomerulonephritis is a form of glomerulonephritis associated primarily with the... more...

MalaCards based summary: Mesangial Proliferative Glomerulonephritis, also known as glomerulonephritis - mesangial proliferative, is related to proliferative glomerulonephritis and glomerulonephritis. An important gene associated with Mesangial Proliferative Glomerulonephritis is CCR1 (chemokine (C-C motif) receptor 1), and among its related pathways are Agents Acting on the Renin-Angiotensin System Pathway, Pharmacodynamics and Neuropeptides signaling through G protein alpha i and G protein alpha q. The compounds shikonin and mdms have been mentioned in the context of this disorder. Affiliated tissues include brain, kidney and lung, and related mouse phenotypes are renal/urinary system and vision/eye.

Related Diseases for Mesangial Proliferative Glomerulonephritis

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Diseases related to Mesangial Proliferative Glomerulonephritis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 107)
idRelated DiseaseScoreTop Affiliating Genes
1proliferative glomerulonephritis32.6CCL2, CD79A
2glomerulonephritis32.2CCL2, CCR5, AGTR1, CD79A
3acute poststreptococcal glomerulonephritis31.3CD79A
4nephritis31.2CD79A, THY1, CCL2
5connective tissue disease30.6CD79A, IL6, CCL2
6proteinuria30.0EDN1, CD79A, THY1, VEGFA, CCL2, AGTR1
7arthritis29.8AGTR1, CCR1, IL6, CCR5, CCL2, FGF2
8myeloma29.5CCR1, VEGFA, IL6, MAPK1, CD79A, FGF2
9nephrotic syndrome10.7
10hepatitis10.5
11diabetic macular edema10.5VEGFA
12interstitial nephritis10.4
13castleman's disease10.4
14polymyositis10.4
15central retinal vein occlusion10.4VEGFA
16classic kaposi sarcoma10.4IL6
17syphilis10.4CD79A, CCR5
18lipoid nephrosis10.3CCL2, CD79A
19focal segmental glomerulosclerosis10.3CD79A, AGTR1
20cor pulmonale10.3AGTR1, EDN1
21c1q deficiency10.3
22hepatitis c virus10.3
23leprosy10.3
24multiple myeloma10.3
25myasthenia gravis10.3
26hepatitis c10.3
27cryoglobulinemia10.3
28hepatitis a10.3
29mixed connective tissue disease10.3
30hellp syndrome10.3
31influenza10.3
32psoriasis10.3
33steroid-resistant nephrotic syndrome10.3
34endotheliitis10.3
35sporadic idiopathic steroid-resistant nephrotic syndrome with diffuse mesangial proliferation10.3
36familial idiopathic steroid-resistant nephrotic syndrome with diffuse mesangial proliferation10.3
37idiopathic steroid-sensitive nephrotic syndrome with diffuse mesangial proliferation10.3
38arteriosclerosis10.3CCL2, EDN1
39periapical granuloma10.3CCL2, CCR5
40raynaud disease10.3EDN1, AGTR1
41polyclonal hypergammaglobulinemia10.3CD79A, IL6
42portal hypertension10.3EDN1, AGTR1
43membranous glomerulonephritis, antenatal10.2CD79A, CCR5, CCL2
44lupus nephritis10.2CCL2, CCR5, CD79A
45chronic myocardial ischemia10.2FGF2, VEGFA
46diabetes mellitus, insulin-dependent10.2CD79A, AGTR1, CCR5
47vascular cancer10.2VEGFA, FGF2
48corneal neovascularization10.2FGF2, VEGFA
49pulmonary sarcoidosis10.2CCR5, CCL2
50interstitial lung disease10.2EDN1, CCL2

Graphical network of the top 20 diseases related to Mesangial Proliferative Glomerulonephritis:



Diseases related to mesangial proliferative glomerulonephritis

Symptoms for Mesangial Proliferative Glomerulonephritis

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Drugs & Therapeutics for Mesangial Proliferative Glomerulonephritis

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Drug clinical trials:

Search ClinicalTrials for Mesangial Proliferative Glomerulonephritis

Search NIH Clinical Center for Mesangial Proliferative Glomerulonephritis

Genetic Tests for Mesangial Proliferative Glomerulonephritis

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Anatomical Context for Mesangial Proliferative Glomerulonephritis

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MalaCards organs/tissues related to Mesangial Proliferative Glomerulonephritis:

31
Brain, Kidney, Lung, Monocytes, T cells, Endothelial

Animal Models for Mesangial Proliferative Glomerulonephritis or affiliated genes

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MGI Mouse Phenotypes related to Mesangial Proliferative Glomerulonephritis:

35 (show all 15)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053678.4AGTR1, CD79A, IL6, CCR1, VEGFA, EDN1
2MP:00053918.3FGF2, IL6, CCL2, VEGFA, CCR5
3MP:00053708.2CCL2, MAPK1, IL6, VEGFA, CCR1, CCR5
4MP:00053818.1IL6, CCR1, CCR5, VEGFA, EDN1, CCL2
5MP:00020068.1CCL2, CCR5, FGF2, MAPK1, VEGFA, IL6
6MP:00053887.8THY1, VEGFA, CCR1, MAPK1, IL6
7MP:00053697.7EDN1, VEGFA, CCL2, CCR5, IL6, MAPK1
8MP:00053877.6VEGFA, CCL2, CCR5, CCR1, IL6, CD79A
9MP:00053977.5FGF2, MAPK1, CCL2, CCR5, CD79A, CCR1
10MP:00053867.5VEGFA, PTPRQ, CCL2, MAPK1, IL6, CCR5
11MP:00053847.4FGF2, IL6, CCR1, VEGFA, CCR5, MAPK1
12MP:00053857.2CCL2, FGF2, AGTR1, VEGFA, MAPK1, CCR1
13MP:00107687.0FGF2, MAPK1, AGTR1, EDN1, VEGFA, CCR5
14MP:00053766.9EDN1, VEGFA, CCL2, CCR5, CCR1, IL6
15MP:00036316.7PTPRQ, FGF2, CD79A, MAPK1, IL6, CCR5

Publications for Mesangial Proliferative Glomerulonephritis

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Articles related to Mesangial Proliferative Glomerulonephritis:

(show top 50)    (show all 134)
idTitleAuthorsYear
1
Mesangial proliferative glomerulonephritis with acute tubule interstitial nephritis leading to acute kidney injury in influenza A (H1N1) infection. (24701045)
2014
2
Urinary neopterin: an immune activation marker in mesangial proliferative glomerulonephritis. (24858931)
2014
3
Aldosterone mediates glomerular inflammation in experimental mesangial proliferative glomerulonephritis. (22641568)
2013
4
Association of human leukocyte antigen gene polymorphism and mesangial proliferative glomerulonephritis in a large population-based study. (24649023)
2013
5
Urinary protein markers predict the severity of renal histological lesions in children with mesangial proliferative glomerulonephritis. (22607047)
2012
6
Single application of low-dose mycophenolate mofetil-OX7-immunoliposomes ameliorates experimental mesangial proliferative glomerulonephritis. (21349934)
2011
7
Acute renal failure due to mesangial proliferative glomerulonephritis in a pregnant woman with primary SjAPgren's syndrome. (15917985)
2006
8
CC chemokines and chemokine receptors in IgA nephropathy (IgAN) and in non-IgA mesangial proliferative glomerulonephritis (MesProGN). the immunohistochemical comparative study. (16334979)
2005
9
Immunohistochemical analysis of the interstitial mast cells in rebiopsied patients with idiopathic mesangial proliferative glomerulonephritis. (16092667)
2005
10
Clinicopathologic features, outcome, and therapeutic interventions in four children with isolated C3 mesangial proliferative glomerulonephritis. (15947989)
2005
11
Pulse cyclophosphamide therapy in steroid resistant nephrotic syndrome associated with mesangial proliferative glomerulonephritis. (17642763)
2004
12
Oxidative stress in the pathogenesis of experimental mesangial proliferative glomerulonephritis. (14600028)
2003
13
Glucocorticoid diminishes vascular endothelial growth factor and exacerbates proteinuria in rats with mesangial proliferative glomerulonephritis. (11979343)
2002
14
Therapeutic effect of sulphated hyaluronic acid, a potential selectin-blocking agent, on experimental progressive mesangial proliferative glomerulonephritis. (12375274)
2002
15
Fractalkine expression and the recruitment of CX3CR1+ cells in the prolonged mesangial proliferative glomerulonephritis. (12028445)
2002
16
Interleukin-10 inhibits experimental mesangial proliferative glomerulonephritis. (11982588)
2002
17
PDGF signal transduction inhibition ameliorates experimental mesangial proliferative glomerulonephritis. (11260393)
2001
18
Morphometric comparison of the quantity of the mesangial deposits in rebiopsied patients with idiopathic mesangial proliferative glomerulonephritis. (11518047)
2001
19
Ambulatory blood pressure in patients with mesangial proliferative glomerulonephritis. (11688762)
2001
20
Localization in situ of type VI collagen protein and its mRNA in mesangial proliferative glomerulonephritis using renal biopsy sections. (9930877)
1999
21
Experimental mesangial proliferative glomerulonephritis (the anti-Thy-1.1 model). (10630692)
1999
22
Beneficial effects of a novel inhibitor of platelet-derived growth factor receptor autophosphorylation in the rat with mesangial proliferative glomerulonephritis. (9809476)
1998
23
Proliferating and migrating mesangial cells responding to injury express a novel receptor protein-tyrosine phosphatase in experimental mesangial proliferative glomerulonephritis. (9727007)
1998
24
Mycophenolic acid: a new approach to the therapy of experimental mesangial proliferative glomerulonephritis. (9808091)
1998
25
Activated mesangial cells produce vascular permeability factor in early-stage mesangial proliferative glomerulonephritis. (9773782)
1998
26
Enhanced glomerular profilin gene and protein expression in experimental mesangial proliferative glomerulonephritis. (8651905)
1996
27
Mesangial proliferative glomerulonephritis and nephrotic syndrome with hepatitis A virus infection. (9141810)
1996
28
Suppression of mesangial proliferative glomerulonephritis development in rats by inhibitors of cAMP phosphodiesterase isozymes types III and IV. (8755633)
1996
29
The novel regulatory mechanism of Fas system-mediated apoptosis in mesangial cells: implication to mesangial proliferative glomerulonephritis. (8619833)
1996
30
Endothelin 1 and cyclic guanosine monophosphate in nonimmunological progression of mesangial proliferative glomerulonephritis. (7758332)
1995
31
Idiopathic polymyositis complicated by arthritis and mesangial proliferative glomerulonephritis: case report and review of the literature. (8402004)
1993
32
Mononuclear cell subsets in IgM mesangial proliferative glomerulonephritis. A comparative study with minimal change nephrotic syndrome and immunonegative mesangial proliferative glomerulonephritis. (8247183)
1993
33
Protective role of BCG in the rabbit model of mesangial proliferative glomerulonephritis. (1956554)
1991
34
A case of IgM-associated mesangial proliferative glomerulonephritis with a giant paramesangial spherical deposit. (1798222)
1991
35
IgM-associated primary diffuse mesangial proliferative glomerulonephritis: natural history and prognostic indicators. (1852859)
1991
36
Pathogenic role of polyclonal and polymeric IgA in a murine model of mesangial proliferative glomerulonephritis with IgA deposition. (2044226)
1991
37
Clinicopathological features in patients with isolated C3 mesangial proliferative glomerulonephritis. (2129468)
1990
38
Involvement of IL-6 in mesangial proliferative glomerulonephritis. (2592764)
1989
39
Renal granuloma and mesangial proliferative glomerulonephritis in leprosy. (3221115)
1988
40
Mesangial proliferative glomerulonephritis in a patient with hepatic hydatid cysts: a case report in an African male. (3232184)
1988
41
Mesangial proliferative glomerulonephritis. Natural history and effects of dextran sulfate. (2437347)
1987
42
Effects of triple therapy on the progression of mesangial proliferative glomerulonephritis. (3549083)
1987
43
Mesangial proliferative glomerulonephritis with Legionnaires' disease. A case report. (3983750)
1985
44
Clinical features and glomerular immunofluorescence of renal biopsies from children with nephrotic syndrome due to minimal change disease and two variants of mesangial proliferative glomerulonephritis. (6370883)
1984
45
Mesangial proliferative glomerulonephritis with IgM deposits. Clinicopathologic analysis and evidence for morphologic transitions. (6382035)
1984
46
Mesangial proliferative glomerulonephritis with unusual intramembranous granular dense deposits. (6188567)
1983
47
Long term study of mesangial proliferative glomerulonephritis with IgM deposits. (7329978)
1981
48
Mesangial proliferative glomerulonephritis in mixed connective tissue disease (MCTD). (7363519)
1980
49
Mesangial proliferative glomerulonephritis with irregular intramembranous deposits. Another variant of hypocoplementemic nephritis. (331950)
1977
50
Mesangial proliferative glomerulonephritis in childhood. (4536432)
1973

Variations for Mesangial Proliferative Glomerulonephritis

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Expression for genes affiliated with Mesangial Proliferative Glomerulonephritis

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Search GEO for disease gene expression data for Mesangial Proliferative Glomerulonephritis.

Pathways for genes affiliated with Mesangial Proliferative Glomerulonephritis

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Pathways related to Mesangial Proliferative Glomerulonephritis according to GeneCards Suite gene sharing:

(show top 50)    (show all 51)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.7AGTR1, MAPK1
2
Show member pathways
9.6CCL2, CCR5, CCR1
39.6EDN1, MAPK1
49.5VEGFA, CCL2
59.5MAPK1, IL6
69.5MAPK1, IL6
79.4FGF2, VEGFA
8
Show member pathways
9.3EDN1, MAPK1, AGTR1
9
Show member pathways
9.2FGF2, PDGFD, MAPK1
10
Show member pathways
9.2MAPK1, IL6, CCR5
119.2EDN1, MAPK1, FGF2
12
Show member pathways
9.2CCL2, IL6, MAPK1
139.2MAPK1, IL6, CCL2
14
Show member pathways
Immune response Role of TLRs 3 and 4 in cell antiviral response TICAM1 specific signaling pathways58
Immune response IL 1 signaling pathway58
9.1EDN1, IL6, MAPK1
15
Show member pathways
Immune response BCR pathway58
Fc-epsilon receptor I signaling in mast cells36
9.1VEGFA, MAPK1, CD79A
16
Show member pathways
9.1MAPK1, CCR1, CCR5, CCL2
179.1VEGFA, CCL2, IL6
18
Show member pathways
Development EDNRB signaling58
Development ACM2 and ACM4 activation of ERK58
Cell adhesion Integrin inside out signaling58
Development G Proteins mediated regulation MARK ERK signaling58
Signal transduction IP3 signaling58
Development Angiotensin signaling via PYK258
Development EPO induced MAPK pathway58
9.0AGTR1, CD79A, MAPK1, EDN1
19
Show member pathways
Development VEGF signaling via VEGFR2 generic cascades58
9.0VEGFA, CCL2, MAPK1
20
Show member pathways
9.0MAPK1, VEGFA, EDN1
21
Show member pathways
Cytoskeleton remodeling FAK signaling58
Development Endothelin 1 EDNRA transactivation of EGFR58
9.0MAPK1, VEGFA, EDN1
22
Show member pathways
BCR signaling pathway36
TCR Signaling Pathway36
8.9CCR5, IL6, MAPK1, CD79A
23
Show member pathways
8.9EDN1, CCL2, CCR5, CCR1, AGTR1
24
Show member pathways
Angiogenesis36
8.9FGF2, MAPK1, VEGFA
25
Show member pathways
8.9FGF2, MAPK1, VEGFA
268.9VEGFA, MAPK1, FGF2
278.9VEGFA, MAPK1, FGF2
288.9VEGFA, MAPK1, FGF2
29
Show member pathways
Apoptosis and survival TNFR1 signaling pathway58
TWEAK Signaling Pathway36
Apoptosis Modulation by HSP7036
HIV-1 Nef- Negative effector of Fas and TNF-alpha36
8.9CCL2, CCR5, IL6, MAPK1
30
Show member pathways
8.8IL6, MAPK1, CD79A, FGF2
31
Show member pathways
8.8FGF2, CD79A, MAPK1, IL6
32
Show member pathways
8.8FGF2, CD79A, MAPK1, IL6
33
Show member pathways
8.8TGFB1I1, CCR5, MAPK1
348.8EDN1, CCL2, IL6, MAPK1
35
Show member pathways
8.7CCL2, CCR5, CCR1, IL6, FGF2
36
Show member pathways
Translation Non genomic rapid action of Androgen Receptor58
8.7MAPK1, IL6, TGFB1I1
37
Show member pathways
Signaling Pathways in Glioblastoma36
8.6FGF2, PDGFD, MAPK1, VEGFA
38
Show member pathways
8.6VEGFA, MAPK1, PDGFD, FGF2
39
Show member pathways
8.5THY1, CCL2, CCR5, CCR1, MAPK1
408.5EDN1, VEGFA, IL6, MAPK1
418.5VEGFA, IL6, MAPK1, FGF2
42
Show member pathways
8.5CCL2, IL6, MAPK1, AGTR1, FGF2
43
Show member pathways
IL23-mediated signaling events36
Immune response IL 10 signaling pathway58
Angiopoietin receptor Tie2-mediated signaling36
Development PDGF signaling via STATs and NF kB58
Development Angiopoietin Tie2 signaling58
8.5CCL2, IL6, MAPK1, AGTR1, FGF2
44
Show member pathways
8.5FGF2, AGTR1, MAPK1, IL6, CCL2
458.1VEGFA, IL6, MAPK1, PDGFD, FGF2
46
Show member pathways
7.9FGF2, MAPK1, IL6, CCR1, CCR5, CCL2
47
Show member pathways
7.6EDN1, VEGFA, CCL2, CCR5, CCR1, IL6
48
Show member pathways
7.4TGFB1I1, CCL2, CCR5, CCR1, IL6, MAPK1
49
Show member pathways
7.1EDN1, VEGFA, CCL2, CCR5, CCR1, MAPK1

Compounds for genes affiliated with Mesangial Proliferative Glomerulonephritis

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Compounds related to Mesangial Proliferative Glomerulonephritis according to GeneCards Suite gene sharing:

(show top 50)    (show all 154)
idCompoundScoreTop Affiliating Genes
1shikonin4310.0CCR1, CCR5, CCL2
2mdms439.9CCR1, CCR5, CCL2
3valsartan43 59 28 1212.8CCL2, EDN1, AGTR1
4mip 1alpha439.8CCL2, IL6, CCR5
5irbesartan43 28 49 1212.7CCL2, EDN1, AGTR1
6gw966243 2810.7MAPK1, AGTR1, CCL2
7ccl343 2810.5CCL2, CCR5, CCR1, IL6
8hcec439.5MAPK1, IL6, CCL2
98-isoprostane439.4EDN1, CCL2, IL6, AGTR1
10tpck439.4MAPK1, IL6, CCL2
11verapamil43 28 49 24 1213.3FGF2, EDN1, AGTR1, CCL2
12ro 31 8220439.3CCL2, VEGFA, MAPK1
13candesartan43 49 28 1212.2CCL2, AGTR1, VEGFA
14vitamin d439.2CCR5, IL6, CD79A, AGTR1, CCL2
15carvedilol43 49 28 1212.2AGTR1, EDN1, VEGFA
16bucillamine439.2VEGFA, CD79A, FGF2, IL6
17norepinephrine43 24 1211.1CCL2, CD79A, AGTR1, IL6, EDN1
18rosiglitazone28 43 49 24 1213.1AGTR1, MAPK1, IL6, CCL2
19histamine43 28 2411.1CCR5, CD79A, EDN1, IL6, CCL2
20tgf beta1439.1IL6, AGTR1, CCL2, FGF2
21cytochalasin d43 5910.1FGF2, MAPK1, CCR5, CCL2
22atorvastatin43 49 28 24 1213.0CCL2, IL6, VEGFA, EDN1
23triptolide438.9MAPK1, IL6, CCL2, VEGFA
24isoproterenol43 129.9FGF2, AGTR1, MAPK1, CCL2, EDN1
25simvastatin43 49 59 28 24 1213.9AGTR1, IL6, VEGFA, CCL2, CCR5
26apocynin43 599.9VEGFA, EDN1, MAPK1
27gf 109203x43 599.8EDN1, VEGFA, FGF2, MAPK1
28prostacyclin438.8CCL2, AGTR1, FGF2, EDN1, VEGFA
29suramin43 28 1210.8FGF2, AGTR1, CD79A, MAPK1, VEGFA
30cyclosporin a43 28 5910.8FGF2, EDN1, CCR5, IL6, CD79A, AGTR1
31herbimycin a43 599.8MAPK1, FGF2, CCL2, EDN1, IL6
32ang ii438.8VEGFA, EDN1, AGTR1, CCL2, MAPK1
33heparin43 28 24 1211.8VEGFA, FGF2, AGTR1, CCR1, CD79A, CCR5
34pd 98,059438.7CCL2, FGF2, MAPK1, IL6, EDN1
35alanine438.6CCR5, CCR1, IL6, AGTR1, FGF2, CD79A
3615-deoxy-delta-12,14-prostaglandin j2438.6MAPK1, VEGFA, FGF2, CCL2, IL6
37phosphatidylinositol438.5CCR1, EDN1, MAPK1, CCL2, FGF2, AGTR1
38hyaluronic acid43 249.4VEGFA, IL6, CD79A, FGF2
39ly294002438.4MAPK1, CCL2, IL6, VEGFA, FGF2
40n acetylcysteine438.4IL6, AGTR1, CD79A, MAPK1, VEGFA, CCL2
41nitric oxide43 24 1210.4CCL2, EDN1, AGTR1, MAPK1, IL6, CCR1
42estrogen438.0VEGFA, CCR5, FGF2, CD79A, IL6, MAPK1
43sb 20358043 598.9IL6, VEGFA, CCL2, MAPK1, AGTR1, FGF2
44genistein43 28 59 2 24 1212.9CCL2, MAPK1, AGTR1, IL6, VEGFA, FGF2
45cycloheximide437.7AGTR1, FGF2, EDN1, VEGFA, CCL2, CCR1
46vegf437.6IL6, MAPK1, FGF2, AGTR1, CD79A, CCL2
47dexamethasone43 49 28 1210.5CCL2, CCR5, CCR1, IL6, FGF2, MAPK1
48pge2437.4CD79A, FGF2, MAPK1, IL6, CCR1, CCR5
49actinomycin d437.4CCL2, EDN1, VEGFA, CCR5, CCR1, IL6
50tyrosine436.7TGFB1I1, VEGFA, THY1, CCR5, CCR1, IL6

GO Terms for genes affiliated with Mesangial Proliferative Glomerulonephritis

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Cellular components related to Mesangial Proliferative Glomerulonephritis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1external side of plasma membraneGO:00098978.6CD79A, IL6, CCR1, CCR5, THY1
2extracellular spaceGO:00056158.3FGF2, IL6, CCL2, VEGFA, EDN1
3extracellular regionGO:00055767.6EDN1, VEGFA, CCL2, IL6, PDGFD, FGF2

Biological processes related to Mesangial Proliferative Glomerulonephritis according to GeneCards Suite gene sharing:

(show all 43)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of monocyte chemotaxisGO:009002610.3CCR1, CCR5
2dendritic cell chemotaxisGO:000240710.3CCR1, CCR5
3positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling paGO:005148210.2AGTR1, EDN1
4maternal process involved in parturitionGO:006013710.1EDN1, CCL2
5regulation of vasoconstrictionGO:001922910.1EDN1, AGTR1
6regulation of vascular endothelial growth factor productionGO:001057410.1IL6, CCL2
7chemokine-mediated signaling pathwayGO:007009810.0CCL2, CCR5, CCR1
8negative regulation of hormone secretionGO:004688810.0EDN1, IL6
9monocyte chemotaxisGO:000254810.0CCL2, IL6
10MAPK import into nucleusGO:000018910.0MAPK1, FGF2
11positive regulation of T cell activationGO:00508709.9THY1, CCL2
12calcium-mediated signalingGO:00197229.9AGTR1, CCR5, EDN1
13regulation of angiogenesisGO:00457659.9FGF2, IL6
14B cell receptor signaling pathwayGO:00508539.8CD79A, MAPK1
15lipopolysaccharide-mediated signaling pathwayGO:00316639.8MAPK1, CCL2
16cell migration involved in sprouting angiogenesisGO:00020429.8VEGFA, FGF2
17vascular endothelial growth factor receptor signaling pathwayGO:00480109.8CCL2, VEGFA
18positive regulation of blood vessel endothelial cell migrationGO:00435369.8VEGFA, FGF2
19positive regulation of ERK1 and ERK2 cascadeGO:00703749.7FGF2, IL6, CCR1
20response to amino acidGO:00432009.7IL6, CCL2, EDN1
21positive regulation of nitric oxide biosynthetic processGO:00454299.7IL6, EDN1
22positive regulation of cytosolic calcium ion concentrationGO:00072049.7EDN1, CCR5, CCR1, AGTR1
23MAPK cascadeGO:00001659.7MAPK1, CCR5, CCL2
24response to antibioticGO:00466779.7IL6, CCL2
25positive chemotaxisGO:00509189.7VEGFA, FGF2
26cell surface receptor signaling pathwayGO:00071669.6CCR1, CCR5, CCL2, EDN1
27organ morphogenesisGO:00098879.6FGF2, MAPK1, CCL2
28cell-cell signalingGO:00072679.6CCR1, CCR5, EDN1
29G-protein coupled receptor signaling pathwayGO:00071869.6AGTR1, CCR5, CCL2, EDN1
30positive regulation of cell divisionGO:00517819.5FGF2, PDGFD, VEGFA
31inflammatory responseGO:00069549.5CCL2, CCR5, CCR1, IL6
32positive regulation of endothelial cell proliferationGO:00019389.5VEGFA, CCL2, FGF2
33cellular response to interleukin-1GO:00713479.5CCL2, EDN1
34regulation of cell shapeGO:00083609.4IL6, CCL2, VEGFA
35response to hypoxiaGO:00016669.4EDN1, VEGFA, CCL2
36cytokine-mediated signaling pathwayGO:00192219.3CCL2, CCR1, IL6
37positive regulation of cell migrationGO:00303359.3EDN1, VEGFA, MAPK1
38response to heatGO:00094089.3TGFB1I1, CCL2, IL6
39angiogenesisGO:00015259.2CCL2, VEGFA, THY1
40chemotaxisGO:00069359.1FGF2, MAPK1, CCR1, CCR5, CCL2
41platelet activationGO:00301689.0VEGFA, IL6, MAPK1
42positive regulation of transcription, DNA-templatedGO:00458938.5FGF2, MAPK1, IL6, TGFB1I1
43positive regulation of cell proliferationGO:00082848.5EDN1, VEGFA, IL6, MAPK1, FGF2

Molecular functions related to Mesangial Proliferative Glomerulonephritis according to GeneCards Suite gene sharing:

(show all 11)
idNameGO IDScoreTop Affiliating Genes
1chemokine (C-C motif) ligand 5 bindingGO:007179110.2CCR1, CCR5
2C-C chemokine bindingGO:001995710.1CCR1, CCR5
3C-C chemokine receptor activityGO:001649310.0CCR5, CCR1
4phosphatidylinositol phospholipase C activityGO:00044359.9CCR1, CCR5
5chemokine receptor activityGO:00049509.8CCR1, CCR5
6platelet-derived growth factor receptor bindingGO:00051619.6PDGFD, VEGFA
7chemoattractant activityGO:00420569.1FGF2, VEGFA
8heparin bindingGO:00082019.1VEGFA, CCL2, FGF2
9growth factor activityGO:00080838.9FGF2, PDGFD, IL6, VEGFA
10cytokine activityGO:00051258.8EDN1, VEGFA, IL6, FGF2
11protein bindingGO:00055156.1EDN1, THY1, VEGFA, TGFB1I1, CCR5, CCR1

Products for genes affiliated with Mesangial Proliferative Glomerulonephritis

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Sources for Mesangial Proliferative Glomerulonephritis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet