MCID: MSN001
MIFTS: 43

Mesangial Proliferative Glomerulonephritis malady

Categories: Rare diseases, Nephrological diseases

Aliases & Classifications for Mesangial Proliferative Glomerulonephritis

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Aliases & Descriptions for Mesangial Proliferative Glomerulonephritis:

Name: Mesangial Proliferative Glomerulonephritis 11 48 13 68
Glomerulonephritis - Mesangial Proliferative 48
 
Glomerulonephritis Mesangial Proliferative 50
Mesangial Proliferative Gn 48

Classifications:



External Ids:

Disease Ontology11 DOID:4783
SNOMED-CT62 35546006
NCIt45 C35445

Summaries for Mesangial Proliferative Glomerulonephritis

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Wikipedia:71 Mesangial proliferative glomerulonephritis is a form of glomerulonephritis associated primarily with the... more...

MalaCards based summary: Mesangial Proliferative Glomerulonephritis, also known as glomerulonephritis - mesangial proliferative, is related to c1q deficiency and glomerulonephritis. An important gene associated with Mesangial Proliferative Glomerulonephritis is IL6 (Interleukin 6), and among its related pathways are Validated transcriptional targets of AP1 family members Fra1 and Fra2 and Immune response_MIF-mediated glucocorticoid regulation. Affiliated tissues include bone, t cells and endothelial, and related mouse phenotypes are renal/urinary system and cellular.

Related Diseases for Mesangial Proliferative Glomerulonephritis

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Diseases related to Mesangial Proliferative Glomerulonephritis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 90)
idRelated DiseaseScoreTop Affiliating Genes
1c1q deficiency11.3
2glomerulonephritis10.9
3proliferative glomerulonephritis10.9
4scrotum paget's disease10.5FGF2, IL6
5antigen-peptide-transporter 2 deficiency10.5CCL2, IL6
6vibrio vulnificus infection10.5CCL2, IL6
7benign mammary dysplasia10.5CCL2, IL6
8cutaneous leishmaniasis10.5EDN1, IL6
9opiate dependence10.4CCL2, IL6
10histoplasmosis10.4CCL2, IL6
11west nile fever10.4CCL2, IL6
12hereditary renal cell carcinoma10.4CCL2, IL6
13gasserian ganglion meningioma10.4CCL2, IL6
14sterility due to immotile flagella10.4CCL2, IL6
15anti-basement membrane glomerulonephritis10.4CCL2, IL6
16scrotum melanoma10.4CCL2, IL6
17central gyrate choroidal dystrophy10.4FGF2, IL6
18scarlet fever10.3IL6, MAPK1
19macular amyloidosis10.3CCL2, IL6
20monoclonal paraproteinemia10.3CD79A, IL6
21glomerulosclerosis, focal segmental, 410.3
22focal segmental glomerulosclerosis10.3
23sporadic idiopathic steroid-resistant nephrotic syndrome with diffuse mesangial proliferation10.3
24familial idiopathic steroid-resistant nephrotic syndrome with diffuse mesangial proliferation10.3
25idiopathic steroid-sensitive nephrotic syndrome with diffuse mesangial proliferation10.3
26osmotic diarrhea10.3CCL2, IL6
27mechanical lagophthalmos10.2IL6, MAPK1
28cyclothymic disorder10.2CD79A, IL6
29oesophagostomiasis10.2CCL2, IL6
30lymphocytic colitis10.2CD79A, IL6
31non-secretory myeloma10.2CD79A, IL6
32speech disorder10.2CCL2, FGF2, IL6
33sacrococcygeal teratoma10.2CCL2, IL6
34dental pulp disease10.2CCL2, FGF2, IL6
35foveal hypoplasia 110.2CCL2, FGF2, IL6
36renal fibrosis10.2EDN1, FGF2, IL6
37philophthalmiasis10.2CD79A, IL6
38suppurative uveitis10.2CCL2, CD79A
39epididymis adenomatoid tumor10.2CD79A, IL6
40gingivitis10.1CCL2, EDN1, IL6
41foodborne botulism10.1CD79A, IL6
42iron metabolism disease10.1CCL2, EDN1, IL6
43bladder neck cancer10.1FGF2, IL6
44fundus dystrophy10.1CCL2, EDN1, IL6
45abducens nerve neoplasm10.1CD79A, IL6
46peripheral artery disease10.1CCL2, EDN1, IL6
47hepatitis10.1
48heart lymphoma10.1CD79A, IL6
49coronary artery disease10.1CCL2, EDN1, IL6
50diamond-blackfan anemia 310.1CCL2, EDN1, FGF2

Graphical network of the top 20 diseases related to Mesangial Proliferative Glomerulonephritis:



Diseases related to mesangial proliferative glomerulonephritis

Symptoms & Phenotypes for Mesangial Proliferative Glomerulonephritis

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MGI Mouse Phenotypes related to Mesangial Proliferative Glomerulonephritis according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053678.2CCR1, CD79A, EDN1, GAS6, IL6
2MP:00053848.0AXL, CCR1, CD79A, FGF2, GAS6, IL6
3MP:00053978.0AXL, CCR1, CD79A, FGF2, GAS6, IL6
4MP:00053857.9AXL, CCR1, EDN1, FGF2, GAS6, IL6
5MP:00053877.9AXL, CCL2, CCR1, CD79A, GAS6, IL6
6MP:00053767.6AXL, CCR1, CD79A, EDN1, FGF2, GAS6

Drugs & Therapeutics for Mesangial Proliferative Glomerulonephritis

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Drugs for Mesangial Proliferative Glomerulonephritis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 10)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Calcitriolapproved, nutraceuticalPhase 420132222-06-3134070, 5280453
Synonyms:
(1R,3S)-5-{2-[(1R,3aS,7aR)-1-((R)-5-Hydroxy-1,5-dimethyl-hexyl)-7a-methyl-octahydro-inden-4-ylidene]-ethylidene}-4-methylene-cyclohexane-1,3-diol
(1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(2R)-6-hydroxy-6-methylheptan-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diol
(1S,3R,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-1,3,25-triol
(1S,3R,5Z,7E)-9,10-secocholesta-5,7,10-triene-1,3,25-triol
(1S,3R,5Z,7e)-9,10-Secocholesta-5,7,10-triene-1,3,25-triol
(1alpha,3beta,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-1,3,25-triol
(1alpha,3beta,5Z,7e)-9,10-Secocholesta-5,7,10(19)-triene-1,3,25-triol
(3b,5Z,7E)-9,10-Secocholesta-5,7,10(19)-trienetriol
(5Z,7E)-(1S,3R)-9,10-secocholesta-5,7,10(19)-triene-1,3,25-triol
(5Z,7E)-9,10-Secocholesta-5,7,10(19)-triene-1-alpha,3-beta,25-triol
(5Z,7E)-9,10-Secocholesta-5,7,10(19)-triene-1alpha,3beta,25-triol
(5Z,7e)-(1S,3R)-9,10-Secocholesta-5,7,10(19)-triene-1,3,25-triol
1 alpha,25-Dihydroxyvitamin D3
1,25 (OH)2 D3
1,25 Dihydroxycholecalciferol
1,25(OH)2-20epi-D3
1,25(OH)2D3 & CD4
1,25(OH2)D3
1,25-(OH)2-D3
1,25-(OH)2D3
1,25-DHCC
1,25-DIHYDROXYCHOLECALCIFEROL
1,25-Dihydroxycholecalciferol
1,25-Dihydroxycholecaliferol
1,25-Dihydroxyvitamin D
1,25-Dihydroxyvitamin D3
1,25-dihydroxy vitamin D3
1,25-dihydroxy-20-epi-Vitamin D3
1,25-dihydroxycholecalciferol
1,25D3
1-alpha,-1,25-Dihydroxyvitamin D3
1-alpha,25-Dihydroxycholecalciferol
1-alpha,25-Dihydroxyvitamin D3
1-alpha-25-Dihydroxyvitamin D3
1-alpha-25-dihydroxyvitamin D3
1.Alpha.,25-Dihydroxy-26,27-hexadeuterovitamin D3
17936_FLUKA
17936_SIGMA
1a,25-(OH)2D3
1a,25-Dihydroxycholecalciferol
1a,25-Dihydroxyvitamin D3
1alpha,25(OH)2-D3
1alpha,25(OH)2D3
1alpha,25-Dihydroxycholecalciferol
1alpha,25-Dihydroxyvitamin D
1alpha,25-Dihydroxyvitamin D3
1db1
1α,25(OH)2D3
1α,25-dihydroxycholecalciferol
1α,25-dihydroxyvitamin D3
20-epi-1alpha,25-dihydroxycholecaliferol
25-Dihydroxycholecalciferol
32222-06-3
5-{2-[1-(5-hydroxy-1,5-dimethyl-hexyl)-7a-methyl-octahydro-inden-4-ylidene]-ethylidene}-4-methylene-cyclohexane-1,3-diol
9,10-Seco(5Z,7E)-5,7,10(19)-cholestatriene-1alpha,3beta,25-triol
9,10-Secocholesta-5,7,10(19)-triene-1,3,25-triol, (1.alpha.,3.beta,.5Z,7E)- & CD4
9,10-seco(5Z,7E)-5,7,10(19)-cholestatriene-1alpha, 3beta, 25-triol
AC-1859
AC1NQX1S
 
Ambap32222-06-3
Asentar
BCBcMAP01_000160
BML2-E03
BSPBio_001287
C01673
CCRIS 5522
CD-2027
CHEBI:17823
CHEMBL846
CID5280453
CPD000466393
Calcijex
Calcijex, Silkis, Rocaltrol, Topitriol, Cholecalciferol,Calcitriol
Calcitriol
Calcitriol (JAN/USAN/INN)
Calcitriol [USAN:INN:BAN:JAN]
Calcitriolum
Calcitriolum [INN-Latin]
D00129
D1530_SIGMA
DN 101
DN-101
Decostriol
Dihydroxyvitamin D3
EINECS 250-963-8
HMS1361A09
HMS1791A09
HMS1989A09
HMS2051F06
HMS2089N03
HSDB 3482
IDI1_033757
LMST03020258
LS-53093
MC-1288
MC1288
MLS000759536
MLS001424122
MolPort-002-045-698
NCGC00161327-01
NCGC00161327-04
Ro 21-5535
Ro 215535
Ro-21-5535
Rocaltrol
Rocaltrol (TN)
S1466_Selleck
SAM001246772
SMR000466393
Silkis
Soltriol
Spectrum5_002061
Topitriol
Toptriol
U 49562
Vectical
ZINC03924790
calcitriol
vit D
2Trace ElementsPhase 4, Phase 35802
3Vasoconstrictor AgentsPhase 42027
4MicronutrientsPhase 4, Phase 35802
5VitaminsPhase 4, Phase 35095
6Immunoglobulin APhase 4, Phase 3118
7Bone Density Conservation AgentsPhase 4, Phase 33266
8Calcium, DietaryPhase 45525
9AntibodiesPhase 4, Phase 36045
10ImmunoglobulinsPhase 4, Phase 36045

Interventional clinical trials:

idNameStatusNCT IDPhase
1Calcitriol in the Treatment of Immunoglobulin A NephropathyUnknown statusNCT00862693Phase 4
2Calcitriol in the Treatment of Immunoglobulin A (IgA) NephropathyCompletedNCT00319761Phase 4
3Paricalcitol for the Treatment of Immunoglobulin A NephropathyWithdrawnNCT00599963Phase 3

Search NIH Clinical Center for Mesangial Proliferative Glomerulonephritis

Genetic Tests for Mesangial Proliferative Glomerulonephritis

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Anatomical Context for Mesangial Proliferative Glomerulonephritis

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MalaCards organs/tissues related to Mesangial Proliferative Glomerulonephritis:

36
Bone, T cells, Endothelial, Monocytes, Lung, Brain, Kidney

Publications for Mesangial Proliferative Glomerulonephritis

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Articles related to Mesangial Proliferative Glomerulonephritis:

(show top 50)    (show all 142)
idTitleAuthorsYear
1
Mesangial proliferative glomerulonephritis in murine malaria parasite, Plasmodium chabaudi AS, infected NC mice. (27815652)
2016
2
Pityriasis rubra pilaris and mesangial proliferative glomerulonephritis in a child: Association or coincidence? (26937085)
2016
3
C3 mesangial proliferative glomerulonephritis initially presenting with atypical hemolytic uremic syndrome: a case report. (27460033)
2016
4
Volatile Organic Metabolites Identify Patients with Mesangial Proliferative Glomerulonephritis, IgA Nephropathy and Normal Controls. (26443483)
2015
5
Multicentric Castleman's disease with renal amyloidosis and mesangial proliferative glomerulonephritis: a case report. (25932265)
2015
6
Mesangial proliferative glomerulonephritis with acute tubule interstitial nephritis leading to acute kidney injury in influenza A (H1N1) infection. (24701045)
2014
7
Urinary neopterin: an immune activation marker in mesangial proliferative glomerulonephritis. (24858931)
2014
8
Aldosterone mediates glomerular inflammation in experimental mesangial proliferative glomerulonephritis. (22641568)
2013
9
Association of human leukocyte antigen gene polymorphism and mesangial proliferative glomerulonephritis in a large population-based study. (24649023)
2013
10
Efficacy of antisense monocyte chemoattractant protein-1 (MCP-1) in a rat model of mesangial proliferative glomerulonephritis. (23991758)
2013
11
Differential proteomic analysis of renal tissue in mesangial proliferative glomerulonephritis using iTRAQ technology. (22641580)
2013
12
Mesangial proliferative glomerulonephritis in familial Mediterranean fever patient with E148Q mutation: the first case report. (22261745)
2013
13
Urinary protein markers predict the severity of renal histological lesions in children with mesangial proliferative glomerulonephritis. (22607047)
2012
14
Glomerular expression of hydrogen peroxide-inducible clone-5 in human and rat progressive mesangial proliferative glomerulonephritis. (22286178)
2012
15
Successful treatment of a mesangial proliferative glomerulonephritis with interstitial nephritis associated with Castleman's disease by an anti-interleukin-6 receptor antibody (tocilizumab). (22687845)
2012
16
Altered long non-coding RNA expression profile in patients with IgA-negative mesangial proliferative glomerulonephritis. (22576627)
2012
17
Single application of low-dose mycophenolate mofetil-OX7-immunoliposomes ameliorates experimental mesangial proliferative glomerulonephritis. (21349934)
2011
18
Protein kinase C I^ inhibition ameliorates experimental mesangial proliferative glomerulonephritis. (21575103)
2011
19
Primary SjAPgren's syndrome with mesangial proliferative glomerulonephritis and IgA deposits in a child. (19902265)
2010
20
Contrasting effects of steroids and mizoribine on macrophage activation and glomerular lesions in rat thy-1 mesangial proliferative glomerulonephritis. (20110667)
2010
21
Effect of the absence of interleukin-12 on mesangial proliferative glomerulonephritis induced by habu snake venom. (20030533)
2009
22
Nephroquiz 2: differential diagnoses of mesangial proliferative glomerulonephritis. (19617668)
2009
23
Mesangial proliferative glomerulonephritis with or without IgA deposits: the morphological characters in psoriasis vulgaris. (18332636)
2008
24
The relation of IgM deposition to clinical parameters and histomorphometry in childhood mesangial proliferative glomerulonephritis. (18093746)
2008
25
Tranilast ameliorates experimental mesangial proliferative glomerulonephritis. (18480612)
2008
26
Pathological regression by angiotensin II type 1 receptor blockade in patients with mesangial proliferative glomerulonephritis. (18497456)
2008
27
Polymyositis associated with focal mesangial proliferative glomerulonephritis with depositions of immune complexes. (16541204)
2007
28
Chronic urticaria and mesangial proliferative glomerulonephritis: a case report. (17717029)
2007
29
Acute renal failure due to mesangial proliferative glomerulonephritis in a pregnant woman with primary SjAPgren's syndrome. (15917985)
2006
30
Honokiol, a small molecular weight natural product, alleviates experimental mesangial proliferative glomerulonephritis. (16807544)
2006
31
The cyclin-dependent kinase inhibitor p21 limits murine mesangial proliferative glomerulonephritis. (16179805)
2006
32
Mesangial proliferative glomerulonephritis after autologous stem cell transplantation. (16860199)
2006
33
Immunohistochemical analysis of the interstitial mast cells in rebiopsied patients with idiopathic mesangial proliferative glomerulonephritis. (16092667)
2005
34
Effect of lipo-prostaglandin E1 on mesangial proliferative glomerulonephritis in rats. (16463661)
2005
35
Pharmacokinetic significance of renal OAT3 (SLC22A8) for anionic drug elimination in patients with mesangial proliferative glomerulonephritis. (16247710)
2005
36
Familial Mediterranean fever and mesangial proliferative glomerulonephritis: report of a case and review of the literature. (15971069)
2005
37
CC chemokines and chemokine receptors in IgA nephropathy (IgAN) and in non-IgA mesangial proliferative glomerulonephritis (MesProGN). the immunohistochemical comparative study. (16334979)
2005
38
Clinicopathologic features, outcome, and therapeutic interventions in four children with isolated C3 mesangial proliferative glomerulonephritis. (15947989)
2005
39
All-trans-retinoic acid inhibits the development of mesangial proliferative glomerulonephritis in interleukin-6 transgenic mice. (15795517)
2005
40
Pulse cyclophosphamide therapy in steroid resistant nephrotic syndrome associated with mesangial proliferative glomerulonephritis. (17642763)
2004
41
Mesangial proliferative glomerulonephritis]. (15500128)
2004
42
Gene expression profile in experimental mesangial proliferative glomerulonephritis. (15351794)
2004
43
Oxidative stress in the pathogenesis of experimental mesangial proliferative glomerulonephritis. (14600028)
2003
44
Glucocorticoid diminishes vascular endothelial growth factor and exacerbates proteinuria in rats with mesangial proliferative glomerulonephritis. (11979343)
2002
45
Fractalkine expression and the recruitment of CX3CR1+ cells in the prolonged mesangial proliferative glomerulonephritis. (12028445)
2002
46
Interleukin-10 inhibits experimental mesangial proliferative glomerulonephritis. (11982588)
2002
47
Mesangial proliferative glomerulonephritis triggered by spleno-renal shunt in a cirrhotic patient. (12038661)
2002
48
Therapeutic effect of sulphated hyaluronic acid, a potential selectin-blocking agent, on experimental progressive mesangial proliferative glomerulonephritis. (12375274)
2002
49
P2 receptor antagonist PPADS inhibits mesangial cell proliferation in experimental mesangial proliferative glomerulonephritis. (12371966)
2002
50
PDGF signal transduction inhibition ameliorates experimental mesangial proliferative glomerulonephritis. (11260393)
2001

Variations for Mesangial Proliferative Glomerulonephritis

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Expression for genes affiliated with Mesangial Proliferative Glomerulonephritis

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Search GEO for disease gene expression data for Mesangial Proliferative Glomerulonephritis.

Pathways for genes affiliated with Mesangial Proliferative Glomerulonephritis

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Pathways related to Mesangial Proliferative Glomerulonephritis according to GeneCards Suite gene sharing:

(show all 34)
idSuper pathwaysScoreTop Affiliating Genes
19.8CCL2, IL6
29.7IL6, MAPK1
39.7IL6, MAPK1
49.7IL6, MAPK1
5
Show member pathways
9.6FGF2, MAPK1
69.5EDN1, MAPK1
7
Show member pathways
9.5EDN1, MAPK1
89.5EDN1, MAPK1
99.5CD79A, FGF2, IL6
109.3CCL2, IL6, MAPK1
11
Show member pathways
9.3CCL2, IL6, MAPK1
129.2EDN1, IL6, MAPK1
139.2EDN1, FGF2, MAPK1
149.0CCR1, CD79A, IL6
159.0FGF2, MAPK1, PDGFD
16
Show member pathways
8.9CCL2, FGF2, IL6, MAPK1
178.9CCL2, EDN1, IL6, MAPK1
188.9CCL2, EDN1, IL6, MAPK1
19
Show member pathways
8.8FGF2, GAS6, IL6, PDGFD
208.7FGF2, IL6, MAPK1, PDGFD
218.2FGF2, GAS6, IL6, MAPK1, PDGFD
22
Show member pathways
7.9CD79A, FGF2, GAS6, IL6, MAPK1, PDGFD
23
Show member pathways
7.9CCL2, FGF2, GAS6, IL6, MAPK1, PDGFD
24
Show member pathways
7.7AXL, FGF2, GAS6, IL6, MAPK1, PDGFD
25
Show member pathways
7.7AXL, FGF2, GAS6, IL6, MAPK1, PDGFD
26
Show member pathways
7.5AXL, CCL2, CCR1, EDN1, IL6, MAPK1
27
Show member pathways
7.4AXL, CD79A, FGF2, GAS6, IL6, MAPK1
28
Show member pathways
7.4AXL, CD79A, FGF2, GAS6, IL6, MAPK1
29
Show member pathways
7.3AXL, CCL2, FGF2, GAS6, IL6, MAPK1
30
Show member pathways
7.3AXL, CCL2, FGF2, GAS6, IL6, MAPK1
31
Show member pathways
7.0AXL, CCL2, CCR1, FGF2, GAS6, IL6
32
Show member pathways
7.0CCL2, CCR1, FGF2, GAS6, IL6, MAPK1
33
Show member pathways
6.6AXL, CCL2, CCR1, EDN1, FGF2, IL6
34
Show member pathways
6.5AXL, CCL2, CCR1, FGF2, GAS6, IL6

GO Terms for genes affiliated with Mesangial Proliferative Glomerulonephritis

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Cellular components related to Mesangial Proliferative Glomerulonephritis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1external side of plasma membraneGO:00098979.8CCR1, CD79A, IL6
2extracellular regionGO:00055768.7CCL2, EDN1, FGF2, GAS6, IL6, PDGFD
3extracellular spaceGO:00056157.4AXL, CCL2, EDN1, FGF2, GAS6, IL6

Biological processes related to Mesangial Proliferative Glomerulonephritis according to GeneCards Suite gene sharing:

(show all 43)
idNameGO IDScoreTop Affiliating Genes
1cellular response to dexamethasone stimulusGO:007154910.6CCL2, IL6
2regulation of angiogenesisGO:004576510.6FGF2, IL6
3regulation of vascular endothelial growth factor productionGO:001057410.6CCL2, IL6
4response to antibioticGO:004667710.6CCL2, IL6
5response to bacteriumGO:000961710.6CCL2, IL6
6negative regulation of hormone secretionGO:004688810.5EDN1, IL6
7maternal process involved in parturitionGO:006013710.5CCL2, EDN1
8lipopolysaccharide-mediated signaling pathwayGO:003166310.4CCL2, MAPK1
9neural crest cell developmentGO:001403210.3EDN1, MAPK1
10apoptotic cell clearanceGO:004327710.3AXL, GAS6
11cellular response to interferon-alphaGO:003545710.3AXL, GAS6
12dendritic cell differentiationGO:009702810.3AXL, GAS6
13enzyme linked receptor protein signaling pathwayGO:000716710.3AXL, GAS6
14negative regulation of dendritic cell apoptotic processGO:200066910.3AXL, GAS6
15negative regulation of interferon-gamma productionGO:003268910.3AXL, GAS6
16cellular response to platelet-derived growth factor stimulusGO:003612010.3CCL2, PDGFD
17positive regulation of cytokine-mediated signaling pathwayGO:000196110.3AXL, GAS6
18positive regulation of natural killer cell differentiationGO:003282510.3AXL, GAS6
19agingGO:000756810.2CCL2, FGF2, IL6
20cellular response to interleukin-1GO:007134710.2CCL2, EDN1, IL6
21cellular response to tumor necrosis factorGO:007135610.2CCL2, EDN1, IL6
22response to amino acidGO:004320010.1CCL2, EDN1, IL6
23cellular response to lipopolysaccharideGO:007122210.1AXL, CCL2, IL6
24positive regulation of monocyte chemotaxisGO:009002610.0CCL2, CCR1
25animal organ morphogenesisGO:000988710.0CCL2, FGF2, MAPK1
26cellular response to drugGO:003569010.0CCL2, EDN1, GAS6
27animal organ regenerationGO:00311009.9AXL, CCL2, GAS6
28protein kinase B signalingGO:00434919.9AXL, CCL2, GAS6
29positive regulation of MAP kinase activityGO:00434069.9EDN1, FGF2, PDGFD
30cellular response to hydrogen peroxideGO:00703019.8AXL, IL6, PDGFD
31cytokine-mediated signaling pathwayGO:00192219.8CCL2, CCR1, IL6
32response to woundingGO:00096119.7CCL2, CCR1, IL6
33viral genome replicationGO:00190799.6CCL2, GAS6
34response to lipopolysaccharideGO:00324969.6CCL2, EDN1, IL6, MAPK1
35positive regulation of protein kinase B signalingGO:00518979.6AXL, FGF2, GAS6, IL6
36positive regulation of smooth muscle cell proliferationGO:00486619.6EDN1, FGF2, IL6, PDGFD
37platelet activationGO:00301689.4AXL, GAS6, IL6, MAPK1
38inflammatory responseGO:00069549.2AXL, CCL2, CCR1, IL6
39chemotaxisGO:00069359.2CCL2, CCR1, FGF2, MAPK1
40positive regulation of cell proliferationGO:00082849.0EDN1, FGF2, IL6, MAPK1, PDGFD
41positive regulation of cell migrationGO:00303358.9CCR1, EDN1, MAPK1, PDGFD
42signal transductionGO:00071658.5AXL, CCL2, FGF2, GAS6, MAPK1
43positive regulation of ERK1 and ERK2 cascadeGO:00703748.3CCL2, CCR1, FGF2, GAS6, IL6, PDGFD

Molecular functions related to Mesangial Proliferative Glomerulonephritis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1phosphatidylserine bindingGO:000178610.1AXL, GAS6
2growth factor activityGO:00080839.9FGF2, IL6, PDGFD
3cytokine activityGO:00051259.7CCL2, EDN1, FGF2, IL6
4receptor bindingGO:00051028.9CCL2, EDN1, GAS6, IL6

Sources for Mesangial Proliferative Glomerulonephritis

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet