MCID: MSN001
MIFTS: 43

Mesangial Proliferative Glomerulonephritis malady

Categories: Rare diseases, Nephrological diseases

Aliases & Classifications for Mesangial Proliferative Glomerulonephritis

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Aliases & Descriptions for Mesangial Proliferative Glomerulonephritis:

Name: Mesangial Proliferative Glomerulonephritis 11 47 13 67
Glomerulonephritis - Mesangial Proliferative 47
 
Glomerulonephritis Mesangial Proliferative 49
Mesangial Proliferative Gn 47

Classifications:



External Ids:

Disease Ontology11 DOID:4783
SNOMED-CT61 35546006
NCIt44 C35445

Summaries for Mesangial Proliferative Glomerulonephritis

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Wikipedia:70 Mesangial proliferative glomerulonephritis is a form of glomerulonephritis associated primarily with the... more...

MalaCards based summary: Mesangial Proliferative Glomerulonephritis, also known as glomerulonephritis - mesangial proliferative, is related to c1q deficiency and glomerulonephritis. An important gene associated with Mesangial Proliferative Glomerulonephritis is IL6 (Interleukin 6), and among its related pathways are Validated transcriptional targets of AP1 family members Fra1 and Fra2 and Immune response_MIF-mediated glucocorticoid regulation. Affiliated tissues include bone, t cells and endothelial, and related mouse phenotypes are renal/urinary system and cellular.

Related Diseases for Mesangial Proliferative Glomerulonephritis

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Diseases related to Mesangial Proliferative Glomerulonephritis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 90)
idRelated DiseaseScoreTop Affiliating Genes
1c1q deficiency11.3
2glomerulonephritis10.9
3proliferative glomerulonephritis10.9
4scrotum paget's disease10.5FGF2, IL6
5antigen-peptide-transporter 2 deficiency10.5CCL2, IL6
6vibrio vulnificus infection10.5CCL2, IL6
7benign mammary dysplasia10.5CCL2, IL6
8cutaneous leishmaniasis10.5EDN1, IL6
9opiate dependence10.4CCL2, IL6
10histoplasmosis10.4CCL2, IL6
11west nile fever10.4CCL2, IL6
12hereditary renal cell carcinoma10.4CCL2, IL6
13gasserian ganglion meningioma10.4CCL2, IL6
14sterility due to immotile flagella10.4CCL2, IL6
15anti-basement membrane glomerulonephritis10.4CCL2, IL6
16scrotum melanoma10.4CCL2, IL6
17central gyrate choroidal dystrophy10.4FGF2, IL6
18scarlet fever10.3IL6, MAPK1
19macular amyloidosis10.3CCL2, IL6
20monoclonal paraproteinemia10.3CD79A, IL6
21glomerulosclerosis, focal segmental, 410.3
22focal segmental glomerulosclerosis10.3
23sporadic idiopathic steroid-resistant nephrotic syndrome with diffuse mesangial proliferation10.3
24familial idiopathic steroid-resistant nephrotic syndrome with diffuse mesangial proliferation10.3
25idiopathic steroid-sensitive nephrotic syndrome with diffuse mesangial proliferation10.3
26osmotic diarrhea10.3CCL2, IL6
27mechanical lagophthalmos10.2IL6, MAPK1
28cyclothymic disorder10.2CD79A, IL6
29oesophagostomiasis10.2CCL2, IL6
30lymphocytic colitis10.2CD79A, IL6
31non-secretory myeloma10.2CD79A, IL6
32speech disorder10.2CCL2, FGF2, IL6
33sacrococcygeal teratoma10.2CCL2, IL6
34dental pulp disease10.2CCL2, FGF2, IL6
35foveal hypoplasia 110.2CCL2, FGF2, IL6
36renal fibrosis10.2EDN1, FGF2, IL6
37philophthalmiasis10.2CD79A, IL6
38suppurative uveitis10.2CCL2, CD79A
39epididymis adenomatoid tumor10.2CD79A, IL6
40gingivitis10.1CCL2, EDN1, IL6
41foodborne botulism10.1CD79A, IL6
42iron metabolism disease10.1CCL2, EDN1, IL6
43bladder neck cancer10.1FGF2, IL6
44fundus dystrophy10.1CCL2, EDN1, IL6
45abducens nerve neoplasm10.1CD79A, IL6
46peripheral artery disease10.1CCL2, EDN1, IL6
47hepatitis10.1
48heart lymphoma10.1CD79A, IL6
49coronary artery disease10.1CCL2, EDN1, IL6
50diamond-blackfan anemia 310.1CCL2, EDN1, FGF2

Graphical network of the top 20 diseases related to Mesangial Proliferative Glomerulonephritis:



Diseases related to mesangial proliferative glomerulonephritis

Symptoms for Mesangial Proliferative Glomerulonephritis

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Drugs & Therapeutics for Mesangial Proliferative Glomerulonephritis

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Drugs for Mesangial Proliferative Glomerulonephritis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 10)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Calcitriolapproved, nutraceuticalPhase 420132222-06-3134070, 5280453
Synonyms:
(1R,3S)-5-{2-[(1R,3aS,7aR)-1-((R)-5-Hydroxy-1,5-dimethyl-hexyl)-7a-methyl-octahydro-inden-4-ylidene]-ethylidene}-4-methylene-cyclohexane-1,3-diol
(1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(2R)-6-hydroxy-6-methylheptan-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diol
(1S,3R,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-1,3,25-triol
(1S,3R,5Z,7E)-9,10-secocholesta-5,7,10-triene-1,3,25-triol
(1S,3R,5Z,7e)-9,10-Secocholesta-5,7,10-triene-1,3,25-triol
(1alpha,3beta,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-1,3,25-triol
(1alpha,3beta,5Z,7e)-9,10-Secocholesta-5,7,10(19)-triene-1,3,25-triol
(3b,5Z,7E)-9,10-Secocholesta-5,7,10(19)-trienetriol
(5Z,7E)-(1S,3R)-9,10-secocholesta-5,7,10(19)-triene-1,3,25-triol
(5Z,7E)-9,10-Secocholesta-5,7,10(19)-triene-1-alpha,3-beta,25-triol
(5Z,7E)-9,10-Secocholesta-5,7,10(19)-triene-1alpha,3beta,25-triol
(5Z,7e)-(1S,3R)-9,10-Secocholesta-5,7,10(19)-triene-1,3,25-triol
1 alpha,25-Dihydroxyvitamin D3
1,25 (OH)2 D3
1,25 Dihydroxycholecalciferol
1,25(OH)2-20epi-D3
1,25(OH)2D3 & CD4
1,25(OH2)D3
1,25-(OH)2-D3
1,25-(OH)2D3
1,25-DHCC
1,25-DIHYDROXYCHOLECALCIFEROL
1,25-Dihydroxycholecalciferol
1,25-Dihydroxycholecaliferol
1,25-Dihydroxyvitamin D
1,25-Dihydroxyvitamin D3
1,25-dihydroxy vitamin D3
1,25-dihydroxy-20-epi-Vitamin D3
1,25-dihydroxycholecalciferol
1,25D3
1-alpha,-1,25-Dihydroxyvitamin D3
1-alpha,25-Dihydroxycholecalciferol
1-alpha,25-Dihydroxyvitamin D3
1-alpha-25-Dihydroxyvitamin D3
1-alpha-25-dihydroxyvitamin D3
1.Alpha.,25-Dihydroxy-26,27-hexadeuterovitamin D3
17936_FLUKA
17936_SIGMA
1a,25-(OH)2D3
1a,25-Dihydroxycholecalciferol
1a,25-Dihydroxyvitamin D3
1alpha,25(OH)2-D3
1alpha,25(OH)2D3
1alpha,25-Dihydroxycholecalciferol
1alpha,25-Dihydroxyvitamin D
1alpha,25-Dihydroxyvitamin D3
1db1
1α,25(OH)2D3
1α,25-dihydroxycholecalciferol
1α,25-dihydroxyvitamin D3
20-epi-1alpha,25-dihydroxycholecaliferol
25-Dihydroxycholecalciferol
32222-06-3
5-{2-[1-(5-hydroxy-1,5-dimethyl-hexyl)-7a-methyl-octahydro-inden-4-ylidene]-ethylidene}-4-methylene-cyclohexane-1,3-diol
9,10-Seco(5Z,7E)-5,7,10(19)-cholestatriene-1alpha,3beta,25-triol
9,10-Secocholesta-5,7,10(19)-triene-1,3,25-triol, (1.alpha.,3.beta,.5Z,7E)- & CD4
9,10-seco(5Z,7E)-5,7,10(19)-cholestatriene-1alpha, 3beta, 25-triol
AC-1859
AC1NQX1S
 
Ambap32222-06-3
Asentar
BCBcMAP01_000160
BML2-E03
BSPBio_001287
C01673
CCRIS 5522
CD-2027
CHEBI:17823
CHEMBL846
CID5280453
CPD000466393
Calcijex
Calcijex, Silkis, Rocaltrol, Topitriol, Cholecalciferol,Calcitriol
Calcitriol
Calcitriol (JAN/USAN/INN)
Calcitriol [USAN:INN:BAN:JAN]
Calcitriolum
Calcitriolum [INN-Latin]
D00129
D1530_SIGMA
DN 101
DN-101
Decostriol
Dihydroxyvitamin D3
EINECS 250-963-8
HMS1361A09
HMS1791A09
HMS1989A09
HMS2051F06
HMS2089N03
HSDB 3482
IDI1_033757
LMST03020258
LS-53093
MC-1288
MC1288
MLS000759536
MLS001424122
MolPort-002-045-698
NCGC00161327-01
NCGC00161327-04
Ro 21-5535
Ro 215535
Ro-21-5535
Rocaltrol
Rocaltrol (TN)
S1466_Selleck
SAM001246772
SMR000466393
Silkis
Soltriol
Spectrum5_002061
Topitriol
Toptriol
U 49562
Vectical
ZINC03924790
calcitriol
vit D
2Trace ElementsPhase 4, Phase 35802
3Vasoconstrictor AgentsPhase 42027
4MicronutrientsPhase 4, Phase 35802
5VitaminsPhase 4, Phase 35095
6Immunoglobulin APhase 4, Phase 3118
7Bone Density Conservation AgentsPhase 4, Phase 33266
8Calcium, DietaryPhase 45525
9AntibodiesPhase 4, Phase 36045
10ImmunoglobulinsPhase 4, Phase 36045

Interventional clinical trials:

idNameStatusNCT IDPhase
1Calcitriol in the Treatment of Immunoglobulin A NephropathyUnknown statusNCT00862693Phase 4
2Calcitriol in the Treatment of Immunoglobulin A (IgA) NephropathyCompletedNCT00319761Phase 4
3Paricalcitol for the Treatment of Immunoglobulin A NephropathyWithdrawnNCT00599963Phase 3

Search NIH Clinical Center for Mesangial Proliferative Glomerulonephritis

Genetic Tests for Mesangial Proliferative Glomerulonephritis

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Anatomical Context for Mesangial Proliferative Glomerulonephritis

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MalaCards organs/tissues related to Mesangial Proliferative Glomerulonephritis:

35
Bone, T cells, Endothelial, Monocytes, Lung, Brain, Kidney

Animal Models for Mesangial Proliferative Glomerulonephritis or affiliated genes

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MGI Mouse Phenotypes related to Mesangial Proliferative Glomerulonephritis:

40
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053678.2CCR1, CD79A, EDN1, GAS6, IL6
2MP:00053848.0AXL, CCR1, CD79A, FGF2, GAS6, IL6
3MP:00053978.0AXL, CCR1, CD79A, FGF2, GAS6, IL6
4MP:00053857.9AXL, CCR1, EDN1, FGF2, GAS6, IL6
5MP:00053877.9AXL, CCL2, CCR1, CD79A, GAS6, IL6
6MP:00053767.6AXL, CCR1, CD79A, EDN1, FGF2, GAS6

Publications for Mesangial Proliferative Glomerulonephritis

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Articles related to Mesangial Proliferative Glomerulonephritis:

(show top 50)    (show all 142)
idTitleAuthorsYear
1
Mesangial proliferative glomerulonephritis in murine malaria parasite, Plasmodium chabaudi AS, infected NC mice. (27815652)
2016
2
Volatile Organic Metabolites Identify Patients with Mesangial Proliferative Glomerulonephritis, IgA Nephropathy and Normal Controls. (26443483)
2015
3
Mesangial proliferative glomerulonephritis with acute tubule interstitial nephritis leading to acute kidney injury in influenza A (H1N1) infection. (24701045)
2014
4
Urinary neopterin: an immune activation marker in mesangial proliferative glomerulonephritis. (24858931)
2014
5
Urinary protein markers predict the severity of renal histological lesions in children with mesangial proliferative glomerulonephritis. (22607047)
2012
6
Single application of low-dose mycophenolate mofetil-OX7-immunoliposomes ameliorates experimental mesangial proliferative glomerulonephritis. (21349934)
2011
7
Protein kinase C I^ inhibition ameliorates experimental mesangial proliferative glomerulonephritis. (21575103)
2011
8
Mesangial proliferative glomerulonephritis with or without IgA deposits: the morphological characters in psoriasis vulgaris. (18332636)
2008
9
Polymyositis associated with focal mesangial proliferative glomerulonephritis with depositions of immune complexes. (16541204)
2007
10
Acute renal failure due to mesangial proliferative glomerulonephritis in a pregnant woman with primary SjAPgren's syndrome. (15917985)
2006
11
Immunohistochemical analysis of the interstitial mast cells in rebiopsied patients with idiopathic mesangial proliferative glomerulonephritis. (16092667)
2005
12
Effect of lipo-prostaglandin E1 on mesangial proliferative glomerulonephritis in rats. (16463661)
2005
13
Pharmacokinetic significance of renal OAT3 (SLC22A8) for anionic drug elimination in patients with mesangial proliferative glomerulonephritis. (16247710)
2005
14
Familial Mediterranean fever and mesangial proliferative glomerulonephritis: report of a case and review of the literature. (15971069)
2005
15
Pulse cyclophosphamide therapy in steroid resistant nephrotic syndrome associated with mesangial proliferative glomerulonephritis. (17642763)
2004
16
Oxidative stress in the pathogenesis of experimental mesangial proliferative glomerulonephritis. (14600028)
2003
17
Glucocorticoid diminishes vascular endothelial growth factor and exacerbates proteinuria in rats with mesangial proliferative glomerulonephritis. (11979343)
2002
18
Fractalkine expression and the recruitment of CX3CR1+ cells in the prolonged mesangial proliferative glomerulonephritis. (12028445)
2002
19
Interleukin-10 inhibits experimental mesangial proliferative glomerulonephritis. (11982588)
2002
20
Mesangial proliferative glomerulonephritis triggered by spleno-renal shunt in a cirrhotic patient. (12038661)
2002
21
PDGF signal transduction inhibition ameliorates experimental mesangial proliferative glomerulonephritis. (11260393)
2001
22
Morphometric comparison of the quantity of the mesangial deposits in rebiopsied patients with idiopathic mesangial proliferative glomerulonephritis. (11518047)
2001
23
Podocyte injuries exacerbate mesangial proliferative glomerulonephritis. (11737593)
2001
24
Mesangial proliferative glomerulonephritis with predominant mesangial IgG deposition in renal allograft. (11096326)
2000
25
Role of matrix metalloproteinases in mesangial proliferative glomerulonephritis. (11031721)
2000
26
Unusual presentation of mesangial proliferative glomerulonephritis in HELLP syndrome associated with acute renal failure. (11041296)
2000
27
Experimental mesangial proliferative glomerulonephritis (the anti-Thy-1.1 model). (10630692)
1999
28
Pentoxifylline attenuates experimental mesangial proliferative glomerulonephritis. (10469361)
1999
29
Beneficial effects of a novel inhibitor of platelet-derived growth factor receptor autophosphorylation in the rat with mesangial proliferative glomerulonephritis. (9809476)
1998
30
Proliferating and migrating mesangial cells responding to injury express a novel receptor protein-tyrosine phosphatase in experimental mesangial proliferative glomerulonephritis. (9727007)
1998
31
Mycophenolic acid: a new approach to the therapy of experimental mesangial proliferative glomerulonephritis. (9808091)
1998
32
Activated mesangial cells produce vascular permeability factor in early-stage mesangial proliferative glomerulonephritis. (9773782)
1998
33
Mesangial proliferative glomerulonephritis in chronic obstructive pulmonary disease. (10218320)
1998
34
AT1-receptor antagonists abolish glomerular MCP-1 expression in a model of mesangial proliferative glomerulonephritis. (9567217)
1998
35
Enhanced glomerular profilin gene and protein expression in experimental mesangial proliferative glomerulonephritis. (8651905)
1996
36
Mesangial proliferative glomerulonephritis and nephrotic syndrome with hepatitis A virus infection. (9141810)
1996
37
Endothelin 1 and cyclic guanosine monophosphate in nonimmunological progression of mesangial proliferative glomerulonephritis. (7758332)
1995
38
Long-term prognosis and prognostic factors of Japanese children with mesangial proliferative glomerulonephritis without IgA deposition. (7572145)
1995
39
Interleukin-4 expression in mesangial proliferative glomerulonephritis. (8311082)
1994
40
Idiopathic polymyositis complicated by arthritis and mesangial proliferative glomerulonephritis: case report and review of the literature. (8402004)
1993
41
Mesangial proliferative glomerulonephritis induced in rats by a lentil lectin and its antibodies. (8426083)
1993
42
Protective role of BCG in the rabbit model of mesangial proliferative glomerulonephritis. (1956554)
1991
43
IgM-associated primary diffuse mesangial proliferative glomerulonephritis: natural history and prognostic indicators. (1852859)
1991
44
Pathogenic role of polyclonal and polymeric IgA in a murine model of mesangial proliferative glomerulonephritis with IgA deposition. (2044226)
1991
45
Mesangial proliferative glomerulonephritis associated with multiple myeloma. (3901749)
1985
46
Acute renal failure and tubular necrosis associated with hematuria due to mesangial proliferative glomerulonephritis. (6525773)
1984
47
Mesangial proliferative glomerulonephritis with unusual intramembranous granular dense deposits. (6188567)
1983
48
Long term study of mesangial proliferative glomerulonephritis with IgM deposits. (7329978)
1981
49
Focal mesangial proliferative glomerulonephritis in the rat caused by Habu snake venom: the role of platelets. (444423)
1979
50
Mesangial proliferative glomerulonephritis. (355724)
1978

Variations for Mesangial Proliferative Glomerulonephritis

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Expression for genes affiliated with Mesangial Proliferative Glomerulonephritis

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Search GEO for disease gene expression data for Mesangial Proliferative Glomerulonephritis.

Pathways for genes affiliated with Mesangial Proliferative Glomerulonephritis

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Pathways related to Mesangial Proliferative Glomerulonephritis according to GeneCards Suite gene sharing:

(show all 34)
idSuper pathwaysScoreTop Affiliating Genes
19.8CCL2, IL6
29.7IL6, MAPK1
39.7IL6, MAPK1
49.7IL6, MAPK1
5
Show member pathways
9.6FGF2, MAPK1
69.5EDN1, MAPK1
7
Show member pathways
9.5EDN1, MAPK1
89.5EDN1, MAPK1
99.5CD79A, FGF2, IL6
109.3CCL2, IL6, MAPK1
11
Show member pathways
9.3CCL2, IL6, MAPK1
129.2EDN1, IL6, MAPK1
139.2EDN1, FGF2, MAPK1
149.0CCR1, CD79A, IL6
159.0FGF2, MAPK1, PDGFD
16
Show member pathways
8.9CCL2, FGF2, IL6, MAPK1
178.9CCL2, EDN1, IL6, MAPK1
188.9CCL2, EDN1, IL6, MAPK1
19
Show member pathways
8.8FGF2, GAS6, IL6, PDGFD
208.7FGF2, IL6, MAPK1, PDGFD
218.2FGF2, GAS6, IL6, MAPK1, PDGFD
22
Show member pathways
7.9CD79A, FGF2, GAS6, IL6, MAPK1, PDGFD
23
Show member pathways
7.9CCL2, FGF2, GAS6, IL6, MAPK1, PDGFD
24
Show member pathways
7.7AXL, FGF2, GAS6, IL6, MAPK1, PDGFD
25
Show member pathways
7.7AXL, FGF2, GAS6, IL6, MAPK1, PDGFD
26
Show member pathways
7.5AXL, CCL2, CCR1, EDN1, IL6, MAPK1
27
Show member pathways
7.4AXL, CD79A, FGF2, GAS6, IL6, MAPK1
28
Show member pathways
7.4AXL, CD79A, FGF2, GAS6, IL6, MAPK1
29
Show member pathways
7.3AXL, CCL2, FGF2, GAS6, IL6, MAPK1
30
Show member pathways
7.3AXL, CCL2, FGF2, GAS6, IL6, MAPK1
31
Show member pathways
7.0AXL, CCL2, CCR1, FGF2, GAS6, IL6
32
Show member pathways
7.0CCL2, CCR1, FGF2, GAS6, IL6, MAPK1
33
Show member pathways
6.6AXL, CCL2, CCR1, EDN1, FGF2, IL6
34
Show member pathways
6.5AXL, CCL2, CCR1, FGF2, GAS6, IL6

GO Terms for genes affiliated with Mesangial Proliferative Glomerulonephritis

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Cellular components related to Mesangial Proliferative Glomerulonephritis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1external side of plasma membraneGO:00098979.1CCR1, CD79A, IL6
2extracellular regionGO:00055767.7CCL2, EDN1, FGF2, GAS6, IL6, PDGFD
3extracellular spaceGO:00056157.4AXL, CCL2, EDN1, FGF2, GAS6, IL6

Biological processes related to Mesangial Proliferative Glomerulonephritis according to GeneCards Suite gene sharing:

(show all 43)
idNameGO IDScoreTop Affiliating Genes
1regulation of vascular endothelial growth factor productionGO:001057410.5CCL2, IL6
2negative regulation of hormone secretionGO:004688810.5EDN1, IL6
3regulation of angiogenesisGO:004576510.4FGF2, IL6
4response to bacteriumGO:000961710.3CCL2, IL6
5response to antibioticGO:004667710.3CCL2, IL6
6lipopolysaccharide-mediated signaling pathwayGO:003166310.2CCL2, MAPK1
7negative regulation of dendritic cell apoptotic processGO:200066910.2AXL, GAS6
8positive regulation of natural killer cell differentiationGO:003282510.2AXL, GAS6
9cellular response to interferon-alphaGO:003545710.2AXL, GAS6
10maternal process involved in parturitionGO:006013710.2CCL2, EDN1
11negative regulation of interferon-gamma productionGO:003268910.2AXL, GAS6
12apoptotic cell clearanceGO:004327710.2AXL, GAS6
13positive regulation of cytokine-mediated signaling pathwayGO:000196110.2AXL, GAS6
14enzyme linked receptor protein signaling pathwayGO:000716710.1AXL, GAS6
15neural crest cell developmentGO:001403210.1EDN1, MAPK1
16dendritic cell differentiationGO:009702810.1AXL, GAS6
17cellular response to platelet-derived growth factor stimulusGO:003612010.1CCL2, PDGFD
18viral genome replicationGO:001907910.1CCL2, GAS6
19cellular response to dexamethasone stimulusGO:007154910.0CCL2, IL6
20response to amino acidGO:004320010.0CCL2, EDN1, IL6
21cellular response to interleukin-1GO:00713479.9CCL2, EDN1, IL6
22cellular response to tumor necrosis factorGO:00713569.9CCL2, EDN1, IL6
23positive regulation of monocyte chemotaxisGO:00900269.8CCL2, CCR1
24cellular response to lipopolysaccharideGO:00712229.8AXL, CCL2, IL6
25protein kinase B signalingGO:00434919.8AXL, CCL2, GAS6
26animal organ morphogenesisGO:00098879.7CCL2, FGF2, MAPK1
27agingGO:00075689.7CCL2, FGF2, IL6
28animal organ regenerationGO:00311009.7AXL, CCL2, GAS6
29cellular response to drugGO:00356909.5CCL2, EDN1, GAS6
30positive regulation of MAP kinase activityGO:00434069.5EDN1, FGF2, PDGFD
31cytokine-mediated signaling pathwayGO:00192219.5CCL2, CCR1, IL6
32response to woundingGO:00096119.5CCL2, CCR1, IL6
33cellular response to hydrogen peroxideGO:00703019.5AXL, IL6, PDGFD
34positive regulation of protein kinase B signalingGO:00518979.4AXL, FGF2, GAS6, IL6
35positive regulation of smooth muscle cell proliferationGO:00486619.4EDN1, FGF2, IL6, PDGFD
36response to lipopolysaccharideGO:00324969.3CCL2, EDN1, IL6, MAPK1
37platelet activationGO:00301689.1AXL, GAS6, IL6, MAPK1
38inflammatory responseGO:00069548.9AXL, CCL2, CCR1, IL6
39chemotaxisGO:00069358.7CCL2, CCR1, FGF2, MAPK1
40signal transductionGO:00071658.3AXL, CCL2, FGF2, GAS6, MAPK1
41positive regulation of cell migrationGO:00303358.2CCR1, EDN1, MAPK1, PDGFD
42positive regulation of cell proliferationGO:00082848.0EDN1, FGF2, IL6, MAPK1, PDGFD
43positive regulation of ERK1 and ERK2 cascadeGO:00703747.5CCL2, CCR1, FGF2, GAS6, IL6, PDGFD

Molecular functions related to Mesangial Proliferative Glomerulonephritis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1phosphatidylserine bindingGO:00017869.9AXL, GAS6
2growth factor activityGO:00080839.4FGF2, IL6, PDGFD
3cytokine activityGO:00051259.3CCL2, EDN1, FGF2, IL6
4receptor bindingGO:00051028.9CCL2, EDN1, GAS6, IL6

Sources for Mesangial Proliferative Glomerulonephritis

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
26GTR
27HGMD
28HMDB
29ICD10
30ICD10 via Orphanet
31ICD9CM
32IUPHAR
33KEGG
36MedGen
38MeSH
39MESH via Orphanet
40MGI
43NCI
44NCIt
45NDF-RT
48NINDS
49Novoseek
51OMIM
52OMIM via Orphanet
56PubMed
57QIAGEN
62SNOMED-CT via Orphanet
66Tumor Gene Family of Databases
67UMLS
68UMLS via Orphanet