MCID: MSN001
MIFTS: 38

Mesangial Proliferative Glomerulonephritis malady

Rare diseases, Nephrological diseases categories

Aliases & Classifications for Mesangial Proliferative Glomerulonephritis

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Aliases & Descriptions for Mesangial Proliferative Glomerulonephritis:

Name: Mesangial Proliferative Glomerulonephritis 10 45 12 65
Glomerulonephritis - Mesangial Proliferative 45
 
Glomerulonephritis Mesangial Proliferative 47
Mesangial Proliferative Gn 45


Classifications:



External Ids:

Disease Ontology10 DOID:4783
SNOMED-CT59 35546006
NCIt42 C35445

Summaries for Mesangial Proliferative Glomerulonephritis

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Wikipedia:68 Mesangial proliferative glomerulonephritis is a form of glomerulonephritis associated primarily with the... more...

MalaCards based summary: Mesangial Proliferative Glomerulonephritis, also known as glomerulonephritis - mesangial proliferative, is related to interstitial nephritis and endotheliitis. An important gene associated with Mesangial Proliferative Glomerulonephritis is IL6 (Interleukin 6), and among its related pathways are Immune response_MIF-mediated glucocorticoid regulation and Syndecan-1-mediated signaling events. Affiliated tissues include t cells, endothelial and monocytes, and related mouse phenotypes are liver/biliary system and tumorigenesis.

Related Diseases for Mesangial Proliferative Glomerulonephritis

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Diseases related to Mesangial Proliferative Glomerulonephritis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 88)
idRelated DiseaseScoreTop Affiliating Genes
1interstitial nephritis30.8CCL2, EDN1, IL6
2endotheliitis30.8CCL2, IL6
3glomerulonephritis11.4
4proliferative glomerulonephritis11.4
5nephrotic syndrome10.8
6hepatitis10.6
7polymyositis10.5
8c1q deficiency10.3
9hepatitis c virus10.3
10leprosy10.3
11multiple myeloma10.3
12arthritis10.3
13myasthenia gravis10.3
14hellp syndrome10.3
15cryoglobulinemia10.3
16hepatitis c10.3
17hepatitis a10.3
18acute poststreptococcal glomerulonephritis10.3
19mixed connective tissue disease10.3
20amyloidosis10.3
21connective tissue disease10.3
22influenza10.3
23myeloma10.3
24psoriasis10.3
25urticaria10.3
26steroid-resistant nephrotic syndrome10.3
27sporadic idiopathic steroid-resistant nephrotic syndrome with diffuse mesangial proliferation10.3
28familial idiopathic steroid-resistant nephrotic syndrome with diffuse mesangial proliferation10.3
29idiopathic steroid-sensitive nephrotic syndrome with diffuse mesangial proliferation10.3
30anti-hla hyperimmunization10.3CCL2, IL6
31louse-borne relapsing fever10.2CCL2, IL6
32loeffler syndrome10.2CCL2, IL6
33larynx sarcoma10.2FGF2, IL6
34crohn's disease10.2EDN1, IL6
35stalker chitayat syndrome10.2CCL2, IL6
36optic nerve sheath meningioma10.2CCL2, IL6
37congenital chloride diarrhea10.2EDN1, IL6
38male reproductive organ benign neoplasm10.2CCL2, IL6
39retinitis10.2CCL2, IL6
40anterior cerebral artery infarction10.2CCL2, IL6
41echinostomiasis10.2EDN1, IL6
42acute disseminated encephalomyelitis10.2CCL2, IL6
43akinetopsia10.2CCR5, IL6
44extrahepatic bile duct papillary adenoma10.2EDN1, IL6
45familiar fallopian tube carcinoma10.2IL6, MAPK1
46epithelioid malignant peripheral nerve sheath tumor10.2CCR5, IL6
47acute allergic sanguinous otitis media10.1CD79A, IL6
48protozoal dysentery10.1CD79A, IL6
49cicatricial lagophthalmos10.1IL6, MAPK1
50dawson disease10.1CCL2, IL6

Graphical network of the top 20 diseases related to Mesangial Proliferative Glomerulonephritis:



Diseases related to mesangial proliferative glomerulonephritis

Symptoms for Mesangial Proliferative Glomerulonephritis

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Drugs & Therapeutics for Mesangial Proliferative Glomerulonephritis

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Drugs for Mesangial Proliferative Glomerulonephritis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Calcitriolapproved, nutraceuticalPhase 415832222-06-3134070, 5280453
Synonyms:
(1R,3S)-5-{2-[(1R,3aS,7aR)-1-((R)-5-Hydroxy-1,5-dimethyl-hexyl)-7a-methyl-octahydro-inden-4-ylidene]-ethylidene}-4-methylene-cyclohexane-1,3-diol
(1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(2R)-6-hydroxy-6-methylheptan-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diol
(1S,3R,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-1,3,25-triol
(1S,3R,5Z,7E)-9,10-secocholesta-5,7,10-triene-1,3,25-triol
(1S,3R,5Z,7e)-9,10-Secocholesta-5,7,10-triene-1,3,25-triol
(1alpha,3beta,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-1,3,25-triol
(1alpha,3beta,5Z,7e)-9,10-Secocholesta-5,7,10(19)-triene-1,3,25-triol
(3b,5Z,7E)-9,10-Secocholesta-5,7,10(19)-trienetriol
(5Z,7E)-(1S,3R)-9,10-secocholesta-5,7,10(19)-triene-1,3,25-triol
(5Z,7E)-9,10-Secocholesta-5,7,10(19)-triene-1-alpha,3-beta,25-triol
(5Z,7E)-9,10-Secocholesta-5,7,10(19)-triene-1alpha,3beta,25-triol
(5Z,7e)-(1S,3R)-9,10-Secocholesta-5,7,10(19)-triene-1,3,25-triol
1 alpha,25-Dihydroxyvitamin D3
1,25 (OH)2 D3
1,25 Dihydroxycholecalciferol
1,25(OH)2-20epi-D3
1,25(OH)2D3 & CD4
1,25(OH2)D3
1,25-(OH)2-D3
1,25-(OH)2D3
1,25-DHCC
1,25-DIHYDROXYCHOLECALCIFEROL
1,25-Dihydroxycholecalciferol
1,25-Dihydroxycholecaliferol
1,25-Dihydroxyvitamin D
1,25-Dihydroxyvitamin D3
1,25-dihydroxy vitamin D3
1,25-dihydroxy-20-epi-Vitamin D3
1,25-dihydroxycholecalciferol
1,25D3
1-alpha,-1,25-Dihydroxyvitamin D3
1-alpha,25-Dihydroxycholecalciferol
1-alpha,25-Dihydroxyvitamin D3
1-alpha-25-Dihydroxyvitamin D3
1-alpha-25-dihydroxyvitamin D3
1.Alpha.,25-Dihydroxy-26,27-hexadeuterovitamin D3
17936_FLUKA
17936_SIGMA
1a,25-(OH)2D3
1a,25-Dihydroxycholecalciferol
1a,25-Dihydroxyvitamin D3
1alpha,25(OH)2-D3
1alpha,25(OH)2D3
1alpha,25-Dihydroxycholecalciferol
1alpha,25-Dihydroxyvitamin D
1alpha,25-Dihydroxyvitamin D3
1db1
1α,25(OH)2D3
1α,25-dihydroxycholecalciferol
1α,25-dihydroxyvitamin D3
20-epi-1alpha,25-dihydroxycholecaliferol
25-Dihydroxycholecalciferol
32222-06-3
5-{2-[1-(5-hydroxy-1,5-dimethyl-hexyl)-7a-methyl-octahydro-inden-4-ylidene]-ethylidene}-4-methylene-cyclohexane-1,3-diol
9,10-Seco(5Z,7E)-5,7,10(19)-cholestatriene-1alpha,3beta,25-triol
9,10-Secocholesta-5,7,10(19)-triene-1,3,25-triol, (1.alpha.,3.beta,.5Z,7E)- & CD4
9,10-seco(5Z,7E)-5,7,10(19)-cholestatriene-1alpha, 3beta, 25-triol
AC-1859
AC1NQX1S
 
Ambap32222-06-3
Asentar
BCBcMAP01_000160
BML2-E03
BSPBio_001287
C01673
CCRIS 5522
CD-2027
CHEBI:17823
CHEMBL846
CID5280453
CPD000466393
Calcijex
Calcijex, Silkis, Rocaltrol, Topitriol, Cholecalciferol,Calcitriol
Calcitriol
Calcitriol (JAN/USAN/INN)
Calcitriol [USAN:INN:BAN:JAN]
Calcitriolum
Calcitriolum [INN-Latin]
D00129
D1530_SIGMA
DN 101
DN-101
Decostriol
Dihydroxyvitamin D3
EINECS 250-963-8
HMS1361A09
HMS1791A09
HMS1989A09
HMS2051F06
HMS2089N03
HSDB 3482
IDI1_033757
LMST03020258
LS-53093
MC-1288
MC1288
MLS000759536
MLS001424122
MolPort-002-045-698
NCGC00161327-01
NCGC00161327-04
Ro 21-5535
Ro 215535
Ro-21-5535
Rocaltrol
Rocaltrol (TN)
S1466_Selleck
SAM001246772
SMR000466393
Silkis
Soltriol
Spectrum5_002061
Topitriol
Toptriol
U 49562
Vectical
ZINC03924790
calcitriol
vit D
2Immunoglobulin APhase 4, Phase 3102
3Calcium, DietaryPhase 43529

Interventional clinical trials:

idNameStatusNCT IDPhase
1Calcitriol in the Treatment of Immunoglobulin A (IgA) NephropathyCompletedNCT00319761Phase 4
2Calcitriol in the Treatment of Immunoglobulin A NephropathyRecruitingNCT00862693Phase 4
3Paricalcitol for the Treatment of Immunoglobulin A NephropathyWithdrawnNCT00599963Phase 3

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Genetic Tests for Mesangial Proliferative Glomerulonephritis

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Anatomical Context for Mesangial Proliferative Glomerulonephritis

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MalaCards organs/tissues related to Mesangial Proliferative Glomerulonephritis:

33
T cells, Endothelial, Monocytes, Lung, Kidney, Brain

Animal Models for Mesangial Proliferative Glomerulonephritis or affiliated genes

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MGI Mouse Phenotypes related to Mesangial Proliferative Glomerulonephritis:

38 (show all 11)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053708.6AXL, CCL2, CCR5, IL6, MAPK1
2MP:00020068.5CCL2, CCR5, FGF2, IL6, MAPK1
3MP:00053698.4CCL2, CCR5, EDN1, FGF2, IL6, MAPK1
4MP:00053918.0AXL, CCL2, CCR5, FGF2, GAS6, IL6
5MP:00053847.3AXL, CCL2, CCR5, CD79A, FGF2, GAS6
6MP:00053857.2AXL, CCL2, CCR5, EDN1, FGF2, GAS6
7MP:00107687.1AXL, CCL2, CCR5, EDN1, FGF2, GAS6
8MP:00036317.1AXL, CCL2, CCR5, CD79A, EDN1, FGF2
9MP:00053877.1AXL, CCL2, CCR5, CD79A, GAS6, IL6
10MP:00053977.0AXL, CCL2, CCR5, CD79A, FGF2, GAS6
11MP:00053766.5AXL, CCL2, CCR5, CD79A, EDN1, FGF2

Publications for Mesangial Proliferative Glomerulonephritis

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Articles related to Mesangial Proliferative Glomerulonephritis:

(show top 50)    (show all 138)
idTitleAuthorsYear
1
Multicentric Castleman's disease with renal amyloidosis and mesangial proliferative glomerulonephritis: a case report. (25932265)
2015
2
Mesangial proliferative glomerulonephritis with acute tubule interstitial nephritis leading to acute kidney injury in influenza A (H1N1) infection. (24701045)
2014
3
Urinary neopterin: an immune activation marker in mesangial proliferative glomerulonephritis. (24858931)
2014
4
Aldosterone mediates glomerular inflammation in experimental mesangial proliferative glomerulonephritis. (22641568)
2013
5
Association of human leukocyte antigen gene polymorphism and mesangial proliferative glomerulonephritis in a large population-based study. (24649023)
2013
6
Urinary protein markers predict the severity of renal histological lesions in children with mesangial proliferative glomerulonephritis. (22607047)
2012
7
Single application of low-dose mycophenolate mofetil-OX7-immunoliposomes ameliorates experimental mesangial proliferative glomerulonephritis. (21349934)
2011
8
Nephroquiz 2: differential diagnoses of mesangial proliferative glomerulonephritis. (19617668)
2009
9
Chronic urticaria and mesangial proliferative glomerulonephritis: a case report. (17717029)
2007
10
Acute renal failure due to mesangial proliferative glomerulonephritis in a pregnant woman with primary SjAPgren's syndrome. (15917985)
2006
11
CC chemokines and chemokine receptors in IgA nephropathy (IgAN) and in non-IgA mesangial proliferative glomerulonephritis (MesProGN). the immunohistochemical comparative study. (16334979)
2005
12
Immunohistochemical analysis of the interstitial mast cells in rebiopsied patients with idiopathic mesangial proliferative glomerulonephritis. (16092667)
2005
13
Clinicopathologic features, outcome, and therapeutic interventions in four children with isolated C3 mesangial proliferative glomerulonephritis. (15947989)
2005
14
Pulse cyclophosphamide therapy in steroid resistant nephrotic syndrome associated with mesangial proliferative glomerulonephritis. (17642763)
2004
15
Glucocorticoid diminishes vascular endothelial growth factor and exacerbates proteinuria in rats with mesangial proliferative glomerulonephritis. (11979343)
2002
16
Therapeutic effect of sulphated hyaluronic acid, a potential selectin-blocking agent, on experimental progressive mesangial proliferative glomerulonephritis. (12375274)
2002
17
Fractalkine expression and the recruitment of CX3CR1+ cells in the prolonged mesangial proliferative glomerulonephritis. (12028445)
2002
18
PDGF signal transduction inhibition ameliorates experimental mesangial proliferative glomerulonephritis. (11260393)
2001
19
Morphometric comparison of the quantity of the mesangial deposits in rebiopsied patients with idiopathic mesangial proliferative glomerulonephritis. (11518047)
2001
20
Localization in situ of type VI collagen protein and its mRNA in mesangial proliferative glomerulonephritis using renal biopsy sections. (9930877)
1999
21
Experimental mesangial proliferative glomerulonephritis (the anti-Thy-1.1 model). (10630692)
1999
22
Beneficial effects of a novel inhibitor of platelet-derived growth factor receptor autophosphorylation in the rat with mesangial proliferative glomerulonephritis. (9809476)
1998
23
Proliferating and migrating mesangial cells responding to injury express a novel receptor protein-tyrosine phosphatase in experimental mesangial proliferative glomerulonephritis. (9727007)
1998
24
Mycophenolic acid: a new approach to the therapy of experimental mesangial proliferative glomerulonephritis. (9808091)
1998
25
Activated mesangial cells produce vascular permeability factor in early-stage mesangial proliferative glomerulonephritis. (9773782)
1998
26
Enhanced glomerular profilin gene and protein expression in experimental mesangial proliferative glomerulonephritis. (8651905)
1996
27
Mesangial proliferative glomerulonephritis and nephrotic syndrome with hepatitis A virus infection. (9141810)
1996
28
Suppression of mesangial proliferative glomerulonephritis development in rats by inhibitors of cAMP phosphodiesterase isozymes types III and IV. (8755633)
1996
29
The novel regulatory mechanism of Fas system-mediated apoptosis in mesangial cells: implication to mesangial proliferative glomerulonephritis. (8619833)
1996
30
Endothelin 1 and cyclic guanosine monophosphate in nonimmunological progression of mesangial proliferative glomerulonephritis. (7758332)
1995
31
Idiopathic polymyositis complicated by arthritis and mesangial proliferative glomerulonephritis: case report and review of the literature. (8402004)
1993
32
Mononuclear cell subsets in IgM mesangial proliferative glomerulonephritis. A comparative study with minimal change nephrotic syndrome and immunonegative mesangial proliferative glomerulonephritis. (8247183)
1993
33
Protective role of BCG in the rabbit model of mesangial proliferative glomerulonephritis. (1956554)
1991
34
A case of IgM-associated mesangial proliferative glomerulonephritis with a giant paramesangial spherical deposit. (1798222)
1991
35
IgM-associated primary diffuse mesangial proliferative glomerulonephritis: natural history and prognostic indicators. (1852859)
1991
36
Pathogenic role of polyclonal and polymeric IgA in a murine model of mesangial proliferative glomerulonephritis with IgA deposition. (2044226)
1991
37
Clinicopathological features in patients with isolated C3 mesangial proliferative glomerulonephritis. (2129468)
1990
38
Involvement of IL-6 in mesangial proliferative glomerulonephritis. (2592764)
1989
39
Renal granuloma and mesangial proliferative glomerulonephritis in leprosy. (3221115)
1988
40
Mesangial proliferative glomerulonephritis in a patient with hepatic hydatid cysts: a case report in an African male. (3232184)
1988
41
Mesangial proliferative glomerulonephritis. Natural history and effects of dextran sulfate. (2437347)
1987
42
Effects of triple therapy on the progression of mesangial proliferative glomerulonephritis. (3549083)
1987
43
Mesangial proliferative glomerulonephritis with Legionnaires' disease. A case report. (3983750)
1985
44
Clinical features and glomerular immunofluorescence of renal biopsies from children with nephrotic syndrome due to minimal change disease and two variants of mesangial proliferative glomerulonephritis. (6370883)
1984
45
Mesangial proliferative glomerulonephritis with IgM deposits. Clinicopathologic analysis and evidence for morphologic transitions. (6382035)
1984
46
Mesangial proliferative glomerulonephritis with unusual intramembranous granular dense deposits. (6188567)
1983
47
Long term study of mesangial proliferative glomerulonephritis with IgM deposits. (7329978)
1981
48
Mesangial proliferative glomerulonephritis in mixed connective tissue disease (MCTD). (7363519)
1980
49
Mesangial proliferative glomerulonephritis with irregular intramembranous deposits. Another variant of hypocoplementemic nephritis. (331950)
1977
50
Mesangial proliferative glomerulonephritis in childhood. (4536432)
1973

Variations for Mesangial Proliferative Glomerulonephritis

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Expression for genes affiliated with Mesangial Proliferative Glomerulonephritis

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Search GEO for disease gene expression data for Mesangial Proliferative Glomerulonephritis.

Pathways for genes affiliated with Mesangial Proliferative Glomerulonephritis

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Pathways related to Mesangial Proliferative Glomerulonephritis according to GeneCards Suite gene sharing:

(show all 30)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.7IL6, MAPK1
29.7IL6, MAPK1
39.7IL6, MAPK1
4
Angiogenesis (WikiPathways)
Show member pathways
9.6IL6, MAPK1
59.5EDN1, MAPK1
6
Show member pathways
9.5EDN1, MAPK1
79.3CCL2, IL6, MAPK1
8
Show member pathways
9.3CCL2, IL6, MAPK1
99.3FGF2, IL6, MAPK1
109.2EDN1, IL6, MAPK1
119.2EDN1, FGF2, MAPK1
12
Show member pathways
8.9CCL2, FGF2, IL6, MAPK1
138.9CCL2, EDN1, IL6, MAPK1
14
B cell receptor signaling pathway (KEGG)
Show member pathways
8.9CCL2, EDN1, IL6, MAPK1
15
Show member pathways
8.9CCL2, CCR5, IL6, MAPK1
168.8FGF2, MAPK1, PDGFD
17
Show member pathways
8.5FGF2, GAS6, IL6, PDGFD
18
Show member pathways
8.5FGF2, IL6, MAPK1, PDGFD
19
Show member pathways
8.5FGF2, IL6, MAPK1, PDGFD
208.5FGF2, IL6, MAPK1, PDGFD
21
Show member pathways
7.6CD79A, FGF2, GAS6, IL6, MAPK1, PDGFD
22
Show member pathways
7.3AXL, FGF2, GAS6, IL6, MAPK1, PDGFD
23
Show member pathways
7.3AXL, FGF2, GAS6, IL6, MAPK1, PDGFD
24
Show member pathways
7.1CCL2, CCR5, FGF2, GAS6, IL6, MAPK1
25
Show member pathways
7.0AXL, CCL2, CCR5, FGF2, GAS6, IL6
26
Show member pathways
7.0AXL, CD79A, FGF2, GAS6, IL6, MAPK1
27
Show member pathways
7.0AXL, CD79A, FGF2, GAS6, IL6, MAPK1
28
Show member pathways
7.0AXL, CCL2, FGF2, GAS6, IL6, MAPK1
29
Show member pathways
7.0AXL, CCL2, FGF2, GAS6, IL6, MAPK1
30
Show member pathways
6.5AXL, CCL2, CCR5, FGF2, GAS6, IL6

GO Terms for genes affiliated with Mesangial Proliferative Glomerulonephritis

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Cellular components related to Mesangial Proliferative Glomerulonephritis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1external side of plasma membraneGO:00098979.9CCR5, CD79A, IL6
2extracellular spaceGO:00056157.9AXL, CCL2, EDN1, FGF2, GAS6, IL6
3extracellular regionGO:00055767.4CCL2, EDN1, FGF2, GAS6, IL6, PDGFD

Biological processes related to Mesangial Proliferative Glomerulonephritis according to GeneCards Suite gene sharing:

(show all 39)
idNameGO IDScoreTop Affiliating Genes
1regulation of vascular endothelial growth factor productionGO:001057410.6CCL2, IL6
2cellular response to interleukin-6GO:007135410.5CCL2, IL6
3negative regulation of hormone secretionGO:004688810.5EDN1, IL6
4regulation of angiogenesisGO:004576510.4FGF2, IL6
5maternal process involved in parturitionGO:006013710.4CCL2, EDN1
6response to antibioticGO:004667710.3CCL2, IL6
7lipopolysaccharide-mediated signaling pathwayGO:003166310.2CCL2, MAPK1
8viral genome replicationGO:001907910.1CCL2, GAS6
9cellular response to dexamethasone stimulusGO:007154910.1CCL2, IL6
10negative regulation of interferon-gamma productionGO:003268910.0AXL, GAS6
11positive regulation of natural killer cell differentiationGO:003282510.0AXL, GAS6
12cellular response to interferon-alphaGO:003545710.0AXL, GAS6
13dendritic cell differentiationGO:009702810.0AXL, GAS6
14negative regulation of dendritic cell apoptotic processGO:200066910.0AXL, GAS6
15enzyme linked receptor protein signaling pathwayGO:00071679.9AXL, GAS6
16response to amino acidGO:00432009.9CCL2, EDN1, IL6
17positive regulation of cytokine-mediated signaling pathwayGO:00019619.9AXL, GAS6
18apoptotic cell clearanceGO:00432779.9AXL, GAS6
19negative regulation of tumor necrosis factor productionGO:00327209.9AXL, GAS6
20cellular response to interleukin-1GO:00713479.9CCL2, EDN1, IL6
21cellular response to tumor necrosis factorGO:00713569.8CCL2, EDN1, IL6
22positive regulation of smooth muscle cell proliferationGO:00486619.8EDN1, FGF2, IL6
23agingGO:00075689.7CCL2, FGF2, IL6
24organ morphogenesisGO:00098879.6CCL2, FGF2, MAPK1
25protein kinase B signalingGO:00434919.6AXL, CCL2, GAS6
26cellular response to drugGO:00356909.6CCL2, EDN1, GAS6
27viral entry into host cellGO:00467189.4AXL, CCR5, GAS6
28response to lipopolysaccharideGO:00324969.3CCL2, EDN1, IL6, MAPK1
29cell surface receptor signaling pathwayGO:00071669.3CCL2, CCR5, CD79A, EDN1
30positive regulation of ERK1 and ERK2 cascadeGO:00703749.2CCL2, FGF2, GAS6, IL6
31positive regulation of cell proliferationGO:00082849.2EDN1, FGF2, IL6, MAPK1
32cellular response to lipopolysaccharideGO:00712229.2AXL, CCL2, CCR5, IL6
33positive regulation of protein kinase B signalingGO:00518979.2AXL, FGF2, GAS6, IL6
34chemotaxisGO:00069359.2CCL2, CCR5, FGF2, MAPK1
35inflammatory responseGO:00069549.1AXL, CCL2, CCR5, IL6
36MAPK cascadeGO:00001659.0CCL2, CCR5, FGF2, MAPK1
37protein phosphorylationGO:00064688.8AXL, CCL2, GAS6, MAPK1
38vascular endothelial growth factor receptor signaling pathwayGO:00480108.7AXL, CCL2, FGF2, MAPK1
39platelet activationGO:00301688.5AXL, GAS6, IL6, MAPK1

Molecular functions related to Mesangial Proliferative Glomerulonephritis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1phosphatidylserine bindingGO:00017869.7AXL, GAS6
2cytokine activityGO:00051259.7EDN1, FGF2, IL6
3growth factor activityGO:00080839.1FGF2, IL6, PDGFD
4receptor bindingGO:00051028.9CCL2, EDN1, GAS6, IL6

Sources for Mesangial Proliferative Glomerulonephritis

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet