MCID: MSN001
MIFTS: 43

Mesangial Proliferative Glomerulonephritis malady

Categories: Rare diseases, Nephrological diseases

Aliases & Classifications for Mesangial Proliferative Glomerulonephritis

About this section

Aliases & Descriptions for Mesangial Proliferative Glomerulonephritis:

Name: Mesangial Proliferative Glomerulonephritis 11 48 13 68
Glomerulonephritis - Mesangial Proliferative 48
 
Glomerulonephritis Mesangial Proliferative 50
Mesangial Proliferative Gn 48

Classifications:



External Ids:

Disease Ontology11 DOID:4783
SNOMED-CT62 35546006
NCIt45 C35445

Summaries for Mesangial Proliferative Glomerulonephritis

About this section
Wikipedia:71 Mesangial proliferative glomerulonephritis is a form of glomerulonephritis associated primarily with the... more...

MalaCards based summary: Mesangial Proliferative Glomerulonephritis, also known as glomerulonephritis - mesangial proliferative, is related to c1q deficiency and glomerulonephritis. An important gene associated with Mesangial Proliferative Glomerulonephritis is IL6 (Interleukin 6), and among its related pathways are Validated transcriptional targets of AP1 family members Fra1 and Fra2 and Immune response_IL-6 signaling pathway. Affiliated tissues include t cells, endothelial and monocytes, and related mouse phenotypes are liver/biliary system and renal/urinary system.

Related Diseases for Mesangial Proliferative Glomerulonephritis

About this section

Diseases related to Mesangial Proliferative Glomerulonephritis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 65)
idRelated DiseaseScoreTop Affiliating Genes
1c1q deficiency11.3
2glomerulonephritis10.9
3proliferative glomerulonephritis10.9
4nephrotic syndrome10.3
5glomerulosclerosis, focal segmental, 410.3
6focal segmental glomerulosclerosis10.3
7sporadic idiopathic steroid-resistant nephrotic syndrome with diffuse mesangial proliferation10.3
8familial idiopathic steroid-resistant nephrotic syndrome with diffuse mesangial proliferation10.3
9idiopathic steroid-sensitive nephrotic syndrome with diffuse mesangial proliferation10.3
10anal paget's disease10.2FGF2, IL6
11schwannoma of ureter10.2CCL2, IL6
12bipolar i disorder10.2FGF2, IL6
13neuroaxonal dystrophy10.2CCL2, IL6
14esophagus lymphoma10.2EDN1, IL6
15generalized atherosclerosis10.1CD79A, IL6
16pyriform sinus cancer10.1CCL2, FGF2, IL6
17optic nerve hypoplasia10.1CCL2, FGF2, IL6
18hepatitis10.1
19central nervous system lymphoma10.1CCL2, EDN1, IL6
20nervous system cancer10.1CCL2, EDN1, IL6
21myelophthisic anemia10.1CCL2, EDN1, IL6
22blackwater fever10.1CD79A, EDN1
23clostridium difficile colitis10.1CD79A, IL6
24subcorneal pustular dermatosis10.0CCL2, EDN1, IL6
25measles10.0IL6, MAPK1
26angiokeratoma10.0CD79A, FGF2
27pyrimidine metabolic disorder10.0CCL2, EDN1, IL6
28lateral cystocele10.0CCL2, CD79A, IL6
29immune-complex glomerulonephritis10.0CCL2, CD79A, IL6
30interstitial nephritis10.0
31polymyositis10.0
32breast apocrine carcinoma in situ10.0CCL2, CD79A, IL6
33bone angioendothelial sarcoma10.0CCL2, CD79A, IL6
34acute chest syndrome10.0CCL2, CD79A, IL6
35paranasal sinus sarcoma10.0CD79A, EDN1, IL6
36oppositional defiant disorder10.0CCL2, EDN1, FGF2, IL6
37autoimmune-related retinopathy and optic neuropathy9.9CCL2, EDN1, IL6
38chronic mucocutaneous candidiasis9.9CD79A, GAS6
39advanced sleep phase syndrome, familial, 19.9CCL2, CCR1, IL6
40uveitis9.9CCL2, CD79A
41malaria9.8
42hepatitis c virus9.8
43leprosy9.8
44multiple myeloma9.8
45pityriasis rubra pilaris9.8
46arthritis9.8
47myasthenia gravis9.8
48hepatitis a9.8
49hemolytic-uremic syndrome9.8
50hellp syndrome9.8

Graphical network of the top 20 diseases related to Mesangial Proliferative Glomerulonephritis:



Diseases related to mesangial proliferative glomerulonephritis

Symptoms & Phenotypes for Mesangial Proliferative Glomerulonephritis

About this section

MGI Mouse Phenotypes related to Mesangial Proliferative Glomerulonephritis according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053708.7AXL, CCR1, CD79A, IL6, MAPK1
2MP:00053678.2CCR1, CD79A, EDN1, GAS6, IL6
3MP:00053978.0AXL, CCR1, CD79A, FGF2, GAS6, IL6
4MP:00053857.9AXL, CCR1, EDN1, FGF2, GAS6, IL6
5MP:00053877.9AXL, CCL2, CCR1, CD79A, GAS6, IL6
6MP:00053767.6AXL, CCR1, CD79A, EDN1, FGF2, GAS6

Drugs & Therapeutics for Mesangial Proliferative Glomerulonephritis

About this section

Drugs for Mesangial Proliferative Glomerulonephritis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 10)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Calcitriolapproved, nutraceuticalPhase 421032222-06-3134070, 5280453
Synonyms:
(1R,3S)-5-{2-[(1R,3aS,7aR)-1-((R)-5-Hydroxy-1,5-dimethyl-hexyl)-7a-methyl-octahydro-inden-4-ylidene]-ethylidene}-4-methylene-cyclohexane-1,3-diol
(1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(2R)-6-hydroxy-6-methylheptan-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diol
(1S,3R,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-1,3,25-triol
(1S,3R,5Z,7E)-9,10-secocholesta-5,7,10-triene-1,3,25-triol
(1alpha,3beta,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-1,3,25-triol
(1α,3β,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-1,3,25-triol
(3b,5Z,7E)-9,10-Secocholesta-5,7,10(19)-trienetriol
(5Z,7E)-(1S,3R)-9,10-secocholesta-5,7,10(19)-triene-1,3,25-triol
(5Z,7E)-9,10-Secocholesta-5,7,10(19)-triene-1-alpha,3-beta,25-triol
(5Z,7E)-9,10-Secocholesta-5,7,10(19)-triene-1alpha,3beta,25-triol
1 alpha,25-Dihydroxyvitamin D3
1,25 (OH)2 D3
1,25 Dihydroxycholecalciferol
1,25(OH)2-20epi-D3
1,25(OH)2D3 & CD4
1,25(OH2)D3
1,25-(OH)2-D3
1,25-(OH)2D3
1,25-DHCC
1,25-DIHYDROXYCHOLECALCIFEROL
1,25-Dihydroxycholecalciferol
1,25-Dihydroxycholecaliferol
1,25-Dihydroxyvitamin D
1,25-Dihydroxyvitamin D3
1,25-dihydroxy vitamin D3
1,25-dihydroxy-20-epi-Vitamin D3
1,25-dihydroxycholecalciferol
1,25D3
1-alpha,-1,25-Dihydroxyvitamin D3
1-alpha,25-Dihydroxycholecalciferol
1-alpha,25-Dihydroxyvitamin D3
1-alpha-25-Dihydroxyvitamin D3
1-alpha-25-dihydroxyvitamin D3
1.Alpha.,25-Dihydroxy-26,27-hexadeuterovitamin D3
17936_FLUKA
17936_SIGMA
1a,25-(OH)2D3
1a,25-Dihydroxycholecalciferol
1a,25-Dihydroxyvitamin D3
1alpha,25(OH)2-D3
1alpha,25(OH)2D3
1alpha,25-Dihydroxycholecalciferol
1alpha,25-Dihydroxyvitamin D
1alpha,25-Dihydroxyvitamin D3
1db1
1α,25(OH)2D3
1α,25-dihydroxycholecalciferol
1α,25-dihydroxyvitamin D3
20-epi-1alpha,25-dihydroxycholecaliferol
25-Dihydroxycholecalciferol
32222-06-3
9,10-Seco(5Z,7E)-5,7,10(19)-cholestatriene-1alpha,3beta,25-triol
9,10-Secocholesta-5,7,10(19)-triene-1,3,25-triol, (1.alpha.,3.beta,.5Z,7E)- & CD4
9,10-seco(5Z,7E)-5,7,10(19)-cholestatriene-1alpha, 3beta, 25-triol
AC-1859
AC1NQX1S
Ambap32222-06-3
 
Asentar
BCBcMAP01_000160
BML2-E03
BSPBio_001287
C01673
CCRIS 5522
CD-2027
CHEBI:17823
CHEMBL846
CID5280453
CPD000466393
Calcijex
Calcijex, Silkis, Rocaltrol, Topitriol, Cholecalciferol,Calcitriol
Calcitriol
Calcitriol (JAN/USAN/INN)
Calcitriol [USAN:INN:BAN:JAN]
Calcitriolum
Calcitriolum [INN-Latin]
D00129
D1530_SIGMA
DN 101
DN-101
Decostriol
Dihydroxyvitamin D3
EINECS 250-963-8
HMS1361A09
HMS1791A09
HMS1989A09
HMS2051F06
HMS2089N03
HSDB 3482
IDI1_033757
LMST03020258
LS-53093
MC-1288
MC1288
MLS000759536
MLS001424122
MolPort-002-045-698
NCGC00161327-01
NCGC00161327-04
Ro 21-5535
Ro 215535
Ro-21-5535
Rocaltrol
Rocaltrol (TN)
S1466_Selleck
SAM001246772
SMR000466393
Silkis
Soltriol
Spectrum5_002061
Topitriol
Toptriol
U 49562
Vectical
ZINC03924790
calcitriol
vit D
2Trace ElementsPhase 4, Phase 36001
3Vasoconstrictor AgentsPhase 42122
4MicronutrientsPhase 4, Phase 36001
5VitaminsPhase 4, Phase 35282
6Immunoglobulin APhase 4, Phase 3120
7Bone Density Conservation AgentsPhase 4, Phase 33376
8Calcium, DietaryPhase 45713
9AntibodiesPhase 4, Phase 36394
10ImmunoglobulinsPhase 4, Phase 36394

Interventional clinical trials:

idNameStatusNCT IDPhase
1Calcitriol in the Treatment of Immunoglobulin A NephropathyUnknown statusNCT00862693Phase 4
2Calcitriol in the Treatment of Immunoglobulin A (IgA) NephropathyCompletedNCT00319761Phase 4
3Paricalcitol for the Treatment of Immunoglobulin A NephropathyWithdrawnNCT00599963Phase 3

Search NIH Clinical Center for Mesangial Proliferative Glomerulonephritis

Genetic Tests for Mesangial Proliferative Glomerulonephritis

About this section

Anatomical Context for Mesangial Proliferative Glomerulonephritis

About this section

MalaCards organs/tissues related to Mesangial Proliferative Glomerulonephritis:

36
T cells, Endothelial, Monocytes, Lung, Kidney, Brain

Publications for Mesangial Proliferative Glomerulonephritis

About this section

Articles related to Mesangial Proliferative Glomerulonephritis:

(show top 50)    (show all 142)
idTitleAuthorsYear
1
Mesangial proliferative glomerulonephritis in murine malaria parasite, Plasmodium chabaudi AS, infected NC mice. (27815652)
2016
2
C3 mesangial proliferative glomerulonephritis initially presenting with atypical hemolytic uremic syndrome: a case report. (27460033)
2016
3
Pityriasis rubra pilaris and mesangial proliferative glomerulonephritis in a child: Association or coincidence? (26937085)
2016
4
Volatile Organic Metabolites Identify Patients with Mesangial Proliferative Glomerulonephritis, IgA Nephropathy and Normal Controls. (26443483)
2015
5
Multicentric Castleman's disease with renal amyloidosis and mesangial proliferative glomerulonephritis: a case report. (25932265)
2015
6
Mesangial proliferative glomerulonephritis with acute tubule interstitial nephritis leading to acute kidney injury in influenza A (H1N1) infection. (24701045)
2014
7
Urinary neopterin: an immune activation marker in mesangial proliferative glomerulonephritis. (24858931)
2014
8
Association of human leukocyte antigen gene polymorphism and mesangial proliferative glomerulonephritis in a large population-based study. (24649023)
2013
9
Mesangial proliferative glomerulonephritis in familial Mediterranean fever patient with E148Q mutation: the first case report. (22261745)
2013
10
Efficacy of antisense monocyte chemoattractant protein-1 (MCP-1) in a rat model of mesangial proliferative glomerulonephritis. (23991758)
2013
11
Differential proteomic analysis of renal tissue in mesangial proliferative glomerulonephritis using iTRAQ technology. (22641580)
2013
12
Aldosterone mediates glomerular inflammation in experimental mesangial proliferative glomerulonephritis. (22641568)
2013
13
Altered long non-coding RNA expression profile in patients with IgA-negative mesangial proliferative glomerulonephritis. (22576627)
2012
14
Urinary protein markers predict the severity of renal histological lesions in children with mesangial proliferative glomerulonephritis. (22607047)
2012
15
Successful treatment of a mesangial proliferative glomerulonephritis with interstitial nephritis associated with Castleman's disease by an anti-interleukin-6 receptor antibody (tocilizumab). (22687845)
2012
16
Glomerular expression of hydrogen peroxide-inducible clone-5 in human and rat progressive mesangial proliferative glomerulonephritis. (22286178)
2012
17
Protein kinase C I^ inhibition ameliorates experimental mesangial proliferative glomerulonephritis. (21575103)
2011
18
Single application of low-dose mycophenolate mofetil-OX7-immunoliposomes ameliorates experimental mesangial proliferative glomerulonephritis. (21349934)
2011
19
Primary SjAPgren's syndrome with mesangial proliferative glomerulonephritis and IgA deposits in a child. (19902265)
2010
20
Contrasting effects of steroids and mizoribine on macrophage activation and glomerular lesions in rat thy-1 mesangial proliferative glomerulonephritis. (20110667)
2010
21
Effect of the absence of interleukin-12 on mesangial proliferative glomerulonephritis induced by habu snake venom. (20030533)
2009
22
Nephroquiz 2: differential diagnoses of mesangial proliferative glomerulonephritis. (19617668)
2009
23
The relation of IgM deposition to clinical parameters and histomorphometry in childhood mesangial proliferative glomerulonephritis. (18093746)
2008
24
Pathological regression by angiotensin II type 1 receptor blockade in patients with mesangial proliferative glomerulonephritis. (18497456)
2008
25
Tranilast ameliorates experimental mesangial proliferative glomerulonephritis. (18480612)
2008
26
Mesangial proliferative glomerulonephritis with or without IgA deposits: the morphological characters in psoriasis vulgaris. (18332636)
2008
27
Chronic urticaria and mesangial proliferative glomerulonephritis: a case report. (17717029)
2007
28
Polymyositis associated with focal mesangial proliferative glomerulonephritis with depositions of immune complexes. (16541204)
2007
29
Acute renal failure due to mesangial proliferative glomerulonephritis in a pregnant woman with primary SjAPgren's syndrome. (15917985)
2006
30
The cyclin-dependent kinase inhibitor p21 limits murine mesangial proliferative glomerulonephritis. (16179805)
2006
31
Honokiol, a small molecular weight natural product, alleviates experimental mesangial proliferative glomerulonephritis. (16807544)
2006
32
Mesangial proliferative glomerulonephritis after autologous stem cell transplantation. (16860199)
2006
33
Familial Mediterranean fever and mesangial proliferative glomerulonephritis: report of a case and review of the literature. (15971069)
2005
34
Immunohistochemical analysis of the interstitial mast cells in rebiopsied patients with idiopathic mesangial proliferative glomerulonephritis. (16092667)
2005
35
Pharmacokinetic significance of renal OAT3 (SLC22A8) for anionic drug elimination in patients with mesangial proliferative glomerulonephritis. (16247710)
2005
36
CC chemokines and chemokine receptors in IgA nephropathy (IgAN) and in non-IgA mesangial proliferative glomerulonephritis (MesProGN). the immunohistochemical comparative study. (16334979)
2005
37
All-trans-retinoic acid inhibits the development of mesangial proliferative glomerulonephritis in interleukin-6 transgenic mice. (15795517)
2005
38
Effect of lipo-prostaglandin E1 on mesangial proliferative glomerulonephritis in rats. (16463661)
2005
39
Clinicopathologic features, outcome, and therapeutic interventions in four children with isolated C3 mesangial proliferative glomerulonephritis. (15947989)
2005
40
Gene expression profile in experimental mesangial proliferative glomerulonephritis. (15351794)
2004
41
Pulse cyclophosphamide therapy in steroid resistant nephrotic syndrome associated with mesangial proliferative glomerulonephritis. (17642763)
2004
42
Mesangial proliferative glomerulonephritis]. (15500128)
2004
43
Oxidative stress in the pathogenesis of experimental mesangial proliferative glomerulonephritis. (14600028)
2003
44
Glucocorticoid diminishes vascular endothelial growth factor and exacerbates proteinuria in rats with mesangial proliferative glomerulonephritis. (11979343)
2002
45
Fractalkine expression and the recruitment of CX3CR1+ cells in the prolonged mesangial proliferative glomerulonephritis. (12028445)
2002
46
Interleukin-10 inhibits experimental mesangial proliferative glomerulonephritis. (11982588)
2002
47
P2 receptor antagonist PPADS inhibits mesangial cell proliferation in experimental mesangial proliferative glomerulonephritis. (12371966)
2002
48
Mesangial proliferative glomerulonephritis triggered by spleno-renal shunt in a cirrhotic patient. (12038661)
2002
49
Therapeutic effect of sulphated hyaluronic acid, a potential selectin-blocking agent, on experimental progressive mesangial proliferative glomerulonephritis. (12375274)
2002
50
PDGF signal transduction inhibition ameliorates experimental mesangial proliferative glomerulonephritis. (11260393)
2001

Variations for Mesangial Proliferative Glomerulonephritis

About this section

Expression for genes affiliated with Mesangial Proliferative Glomerulonephritis

About this section
Search GEO for disease gene expression data for Mesangial Proliferative Glomerulonephritis.

Pathways for genes affiliated with Mesangial Proliferative Glomerulonephritis

About this section

Pathways related to Mesangial Proliferative Glomerulonephritis according to GeneCards Suite gene sharing:

(show all 35)
idSuper pathwaysScoreTop Affiliating Genes
19.8CCL2, IL6
29.7IL6, MAPK1
39.7IL6, MAPK1
4
Show member pathways
9.6FGF2, MAPK1
59.5EDN1, MAPK1
69.5EDN1, MAPK1
7
Show member pathways
9.5EDN1, MAPK1
89.5CD79A, FGF2, IL6
99.5CCL2, FGF2, IL6
109.3CCL2, IL6, MAPK1
11
Show member pathways
9.3CCL2, IL6, MAPK1
129.2EDN1, IL6, MAPK1
13
Show member pathways
9.2EDN1, FGF2, MAPK1
149.0CCL2, EDN1, FGF2, IL6
159.0CCR1, CD79A, IL6
169.0CCL2, CCR1, IL6
17
Show member pathways
8.9CCL2, FGF2, IL6, MAPK1
188.9CCL2, EDN1, IL6, MAPK1
198.9CCL2, EDN1, IL6, MAPK1
20
Show member pathways
8.8FGF2, GAS6, IL6, PDGFD
218.7FGF2, IL6, MAPK1, PDGFD
228.2FGF2, GAS6, IL6, MAPK1, PDGFD
23
Show member pathways
8.1CCL2, CCR1, FGF2, IL6, MAPK1
24
Show member pathways
7.9CD79A, FGF2, GAS6, IL6, MAPK1, PDGFD
25
Show member pathways
7.7AXL, FGF2, GAS6, IL6, MAPK1, PDGFD
26
Show member pathways
7.7AXL, FGF2, GAS6, IL6, MAPK1, PDGFD
27
Show member pathways
7.7AXL, FGF2, GAS6, IL6, MAPK1, PDGFD
28
Show member pathways
7.5AXL, CCL2, CCR1, EDN1, IL6, MAPK1
29
Show member pathways
7.4AXL, CD79A, FGF2, GAS6, IL6, MAPK1
30
Show member pathways
7.4AXL, CD79A, FGF2, GAS6, IL6, MAPK1
31
Show member pathways
7.3AXL, CCL2, FGF2, GAS6, IL6, MAPK1
32
Show member pathways
7.3AXL, CCL2, FGF2, GAS6, IL6, MAPK1
33
Show member pathways
7.0AXL, CCL2, CCR1, FGF2, GAS6, IL6
34
Show member pathways
7.0CCL2, CCR1, FGF2, GAS6, IL6, MAPK1
35
Show member pathways
6.5AXL, CCL2, CCR1, FGF2, GAS6, IL6

GO Terms for genes affiliated with Mesangial Proliferative Glomerulonephritis

About this section

Cellular components related to Mesangial Proliferative Glomerulonephritis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1extracellular regionGO:00055768.2CCL2, EDN1, FGF2, GAS6, IL6, MAPK1
2extracellular spaceGO:00056157.4AXL, CCL2, EDN1, FGF2, GAS6, IL6

Biological processes related to Mesangial Proliferative Glomerulonephritis according to GeneCards Suite gene sharing:

(show all 46)
idNameGO IDScoreTop Affiliating Genes
1cellular response to dexamethasone stimulusGO:007154910.6CCL2, IL6
2regulation of angiogenesisGO:004576510.6FGF2, IL6
3regulation of vascular endothelial growth factor productionGO:001057410.6CCL2, IL6
4response to antibioticGO:004667710.6CCL2, IL6
5response to bacteriumGO:000961710.6CCL2, IL6
6negative regulation of hormone secretionGO:004688810.5EDN1, IL6
7cellular response to fatty acidGO:007139810.5CCL2, EDN1
8maternal process involved in parturitionGO:006013710.5CCL2, EDN1
9positive regulation of protein import into nucleus, translocationGO:003316010.4IL6, MAPK1
10lipopolysaccharide-mediated signaling pathwayGO:003166310.4CCL2, MAPK1
11neural crest cell developmentGO:001403210.3EDN1, MAPK1
12apoptotic cell clearanceGO:004327710.3AXL, GAS6
13cellular response to interferon-alphaGO:003545710.3AXL, GAS6
14dendritic cell differentiationGO:009702810.3AXL, GAS6
15enzyme linked receptor protein signaling pathwayGO:000716710.3AXL, GAS6
16negative regulation of dendritic cell apoptotic processGO:200066910.3AXL, GAS6
17negative regulation of interferon-gamma productionGO:003268910.3AXL, GAS6
18cellular response to platelet-derived growth factor stimulusGO:003612010.3CCL2, PDGFD
19positive regulation of cytokine-mediated signaling pathwayGO:000196110.3AXL, GAS6
20positive regulation of natural killer cell differentiationGO:003282510.3AXL, GAS6
21cellular response to interleukin-1GO:007134710.2CCL2, EDN1, IL6
22cellular response to tumor necrosis factorGO:007135610.2CCL2, EDN1, IL6
23response to amino acidGO:004320010.1CCL2, EDN1, IL6
24cellular response to lipopolysaccharideGO:007122210.1AXL, CCL2, IL6
25positive regulation of monocyte chemotaxisGO:009002610.0CCL2, CCR1
26animal organ morphogenesisGO:000988710.0CCL2, FGF2, MAPK1
27cellular response to drugGO:003569010.0CCL2, EDN1, GAS6
28positive regulation of protein kinase B signalingGO:005189710.0AXL, GAS6, IL6
29animal organ regenerationGO:00311009.9AXL, CCL2, GAS6
30positive regulation of smooth muscle cell proliferationGO:00486619.9EDN1, IL6, PDGFD
31protein kinase B signalingGO:00434919.9AXL, CCL2, GAS6
32positive regulation of MAP kinase activityGO:00434069.9EDN1, FGF2, PDGFD
33cellular response to hydrogen peroxideGO:00703019.8AXL, IL6, PDGFD
34cytokine-mediated signaling pathwayGO:00192219.8CCL2, CCR1, IL6
35response to woundingGO:00096119.7CCL2, CCR1, IL6
36viral genome replicationGO:00190799.6CCL2, GAS6
37response to lipopolysaccharideGO:00324969.6CCL2, EDN1, IL6, MAPK1
38platelet activationGO:00301689.5AXL, GAS6, IL6, MAPK1
39protein phosphorylationGO:00064689.4AXL, CCL2, GAS6, MAPK1
40cell surface receptor signaling pathwayGO:00071669.3CCL2, CCR1, CD79A, EDN1
41inflammatory responseGO:00069549.2AXL, CCL2, CCR1, IL6
42chemotaxisGO:00069359.2CCL2, CCR1, FGF2, MAPK1
43positive regulation of cell proliferationGO:00082849.0EDN1, FGF2, IL6, MAPK1, PDGFD
44positive regulation of cell migrationGO:00303358.9CCR1, EDN1, MAPK1, PDGFD
45positive regulation of ERK1 and ERK2 cascadeGO:00703748.3CCL2, CCR1, FGF2, GAS6, IL6, PDGFD
46signal transductionGO:00071657.7AXL, CCL2, CCR1, FGF2, GAS6, MAPK1

Molecular functions related to Mesangial Proliferative Glomerulonephritis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1growth factor activityGO:00080839.8FGF2, IL6, PDGFD
2cytokine activityGO:00051259.7CCL2, EDN1, FGF2, IL6
3receptor bindingGO:00051028.9CCL2, EDN1, GAS6, IL6

Sources for Mesangial Proliferative Glomerulonephritis

About this section
2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet