MCID: MSN001
MIFTS: 46

Mesangial Proliferative Glomerulonephritis malady

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Aliases & Classifications for Mesangial Proliferative Glomerulonephritis

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Aliases & Descriptions for Mesangial Proliferative Glomerulonephritis:

Name: Mesangial Proliferative Glomerulonephritis 8 42 61
Glomerulonephritis - Mesangial Proliferative 42
 
Glomerulonephritis Mesangial Proliferative 44
Mesangial Proliferative Gn 42


Classifications:



External Ids:

Disease Ontology8 DOID:4783
SNOMED-CT56 35546006
NCIt39 C35445

Summaries for Mesangial Proliferative Glomerulonephritis

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Wikipedia:64 Mesangial proliferative glomerulonephritis is a form of glomerulonephritis associated primarily with the... more...

MalaCards based summary: Mesangial Proliferative Glomerulonephritis, also known as glomerulonephritis - mesangial proliferative, is related to proliferative glomerulonephritis and glomerulonephritis. An important gene associated with Mesangial Proliferative Glomerulonephritis is CCR1 (chemokine (C-C motif) receptor 1), and among its related pathways are Agents Acting on the Renin-Angiotensin System Pathway, Pharmacodynamics and Neuropeptides signaling through G protein alpha i and G protein alpha q. The compounds shikonin and mdms have been mentioned in the context of this disorder. Affiliated tissues include brain, kidney and lung, and related mouse phenotypes are renal/urinary system and vision/eye.

Related Diseases for Mesangial Proliferative Glomerulonephritis

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Diseases related to Mesangial Proliferative Glomerulonephritis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 107)
idRelated DiseaseScoreTop Affiliating Genes
1proliferative glomerulonephritis32.6CCL2, CD79A
2glomerulonephritis32.2CCL2, CCR5, AGTR1, CD79A
3acute poststreptococcal glomerulonephritis31.3CD79A
4nephritis31.2CD79A, THY1, CCL2
5connective tissue disease30.6CD79A, IL6, CCL2
6proteinuria30.0EDN1, CD79A, THY1, VEGFA, CCL2, AGTR1
7arthritis29.8AGTR1, CCR1, IL6, CCR5, CCL2, FGF2
8myeloma29.5CCR1, VEGFA, IL6, MAPK1, CD79A, FGF2
9nephrotic syndrome10.7
10hepatitis10.5
11diabetic macular edema10.5VEGFA
12interstitial nephritis10.4
13castleman's disease10.4
14polymyositis10.4
15central retinal vein occlusion10.4VEGFA
16classic kaposi sarcoma10.4IL6
17syphilis10.4CD79A, CCR5
18lipoid nephrosis10.3CCL2, CD79A
19focal segmental glomerulosclerosis10.3CD79A, AGTR1
20cor pulmonale10.3AGTR1, EDN1
21c1q deficiency10.3
22hepatitis c virus10.3
23leprosy10.3
24multiple myeloma10.3
25myasthenia gravis10.3
26hepatitis c10.3
27cryoglobulinemia10.3
28hepatitis a10.3
29mixed connective tissue disease10.3
30hellp syndrome10.3
31influenza10.3
32psoriasis10.3
33steroid-resistant nephrotic syndrome10.3
34endotheliitis10.3
35sporadic idiopathic steroid-resistant nephrotic syndrome with diffuse mesangial proliferation10.3
36familial idiopathic steroid-resistant nephrotic syndrome with diffuse mesangial proliferation10.3
37idiopathic steroid-sensitive nephrotic syndrome with diffuse mesangial proliferation10.3
38arteriosclerosis10.3CCL2, EDN1
39periapical granuloma10.3CCL2, CCR5
40raynaud disease10.3EDN1, AGTR1
41polyclonal hypergammaglobulinemia10.3CD79A, IL6
42portal hypertension10.3EDN1, AGTR1
43membranous glomerulonephritis, antenatal10.2CD79A, CCR5, CCL2
44lupus nephritis10.2CCL2, CCR5, CD79A
45chronic myocardial ischemia10.2FGF2, VEGFA
46diabetes mellitus, insulin-dependent10.2CD79A, AGTR1, CCR5
47vascular cancer10.2VEGFA, FGF2
48corneal neovascularization10.2FGF2, VEGFA
49pulmonary sarcoidosis10.2CCR5, CCL2
50interstitial lung disease10.2EDN1, CCL2

Graphical network of the top 20 diseases related to Mesangial Proliferative Glomerulonephritis:



Diseases related to mesangial proliferative glomerulonephritis

Symptoms for Mesangial Proliferative Glomerulonephritis

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Drugs & Therapeutics for Mesangial Proliferative Glomerulonephritis

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Drug clinical trials:

Search ClinicalTrials for Mesangial Proliferative Glomerulonephritis

Search NIH Clinical Center for Mesangial Proliferative Glomerulonephritis

Genetic Tests for Mesangial Proliferative Glomerulonephritis

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Anatomical Context for Mesangial Proliferative Glomerulonephritis

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MalaCards organs/tissues related to Mesangial Proliferative Glomerulonephritis:

31
Brain, Kidney, Lung, Monocytes, T cells, Endothelial

Animal Models for Mesangial Proliferative Glomerulonephritis or affiliated genes

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MGI Mouse Phenotypes related to Mesangial Proliferative Glomerulonephritis:

35 (show all 15)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053678.4AGTR1, CD79A, IL6, CCR1, VEGFA, EDN1
2MP:00053918.3FGF2, IL6, CCL2, VEGFA, CCR5
3MP:00053708.2CCL2, MAPK1, IL6, VEGFA, CCR1, CCR5
4MP:00053818.1IL6, CCR1, CCR5, VEGFA, EDN1, CCL2
5MP:00020068.1CCL2, CCR5, FGF2, MAPK1, VEGFA, IL6
6MP:00053887.8THY1, VEGFA, CCR1, MAPK1, IL6
7MP:00053697.7EDN1, VEGFA, CCL2, CCR5, IL6, MAPK1
8MP:00053877.6VEGFA, CCL2, CCR5, CCR1, IL6, CD79A
9MP:00053977.5FGF2, MAPK1, CCL2, CCR5, CD79A, CCR1
10MP:00053867.5VEGFA, PTPRQ, CCL2, MAPK1, IL6, CCR5
11MP:00053847.4FGF2, IL6, CCR1, VEGFA, CCR5, MAPK1
12MP:00053857.2CCL2, FGF2, AGTR1, VEGFA, MAPK1, CCR1
13MP:00107687.0FGF2, MAPK1, AGTR1, EDN1, VEGFA, CCR5
14MP:00053766.9EDN1, VEGFA, CCL2, CCR5, CCR1, IL6
15MP:00036316.7PTPRQ, FGF2, CD79A, MAPK1, IL6, CCR5

Publications for Mesangial Proliferative Glomerulonephritis

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Articles related to Mesangial Proliferative Glomerulonephritis:

(show top 50)    (show all 134)
idTitleAuthorsYear
1
Mesangial proliferative glomerulonephritis with acute tubule interstitial nephritis leading to acute kidney injury in influenza A (H1N1) infection. (24701045)
2014
2
Urinary neopterin: an immune activation marker in mesangial proliferative glomerulonephritis. (24858931)
2014
3
Aldosterone mediates glomerular inflammation in experimental mesangial proliferative glomerulonephritis. (22641568)
2013
4
Association of human leukocyte antigen gene polymorphism and mesangial proliferative glomerulonephritis in a large population-based study. (24649023)
2013
5
Urinary protein markers predict the severity of renal histological lesions in children with mesangial proliferative glomerulonephritis. (22607047)
2012
6
Single application of low-dose mycophenolate mofetil-OX7-immunoliposomes ameliorates experimental mesangial proliferative glomerulonephritis. (21349934)
2011
7
Acute renal failure due to mesangial proliferative glomerulonephritis in a pregnant woman with primary SjAPgren's syndrome. (15917985)
2006
8
CC chemokines and chemokine receptors in IgA nephropathy (IgAN) and in non-IgA mesangial proliferative glomerulonephritis (MesProGN). the immunohistochemical comparative study. (16334979)
2005
9
Immunohistochemical analysis of the interstitial mast cells in rebiopsied patients with idiopathic mesangial proliferative glomerulonephritis. (16092667)
2005
10
Clinicopathologic features, outcome, and therapeutic interventions in four children with isolated C3 mesangial proliferative glomerulonephritis. (15947989)
2005
11
Pulse cyclophosphamide therapy in steroid resistant nephrotic syndrome associated with mesangial proliferative glomerulonephritis. (17642763)
2004
12
Oxidative stress in the pathogenesis of experimental mesangial proliferative glomerulonephritis. (14600028)
2003
13
Glucocorticoid diminishes vascular endothelial growth factor and exacerbates proteinuria in rats with mesangial proliferative glomerulonephritis. (11979343)
2002
14
Therapeutic effect of sulphated hyaluronic acid, a potential selectin-blocking agent, on experimental progressive mesangial proliferative glomerulonephritis. (12375274)
2002
15
Fractalkine expression and the recruitment of CX3CR1+ cells in the prolonged mesangial proliferative glomerulonephritis. (12028445)
2002
16
Interleukin-10 inhibits experimental mesangial proliferative glomerulonephritis. (11982588)
2002
17
PDGF signal transduction inhibition ameliorates experimental mesangial proliferative glomerulonephritis. (11260393)
2001
18
Morphometric comparison of the quantity of the mesangial deposits in rebiopsied patients with idiopathic mesangial proliferative glomerulonephritis. (11518047)
2001
19
Ambulatory blood pressure in patients with mesangial proliferative glomerulonephritis. (11688762)
2001
20
Localization in situ of type VI collagen protein and its mRNA in mesangial proliferative glomerulonephritis using renal biopsy sections. (9930877)
1999
21
Experimental mesangial proliferative glomerulonephritis (the anti-Thy-1.1 model). (10630692)
1999
22
Beneficial effects of a novel inhibitor of platelet-derived growth factor receptor autophosphorylation in the rat with mesangial proliferative glomerulonephritis. (9809476)
1998
23
Proliferating and migrating mesangial cells responding to injury express a novel receptor protein-tyrosine phosphatase in experimental mesangial proliferative glomerulonephritis. (9727007)
1998
24
Mycophenolic acid: a new approach to the therapy of experimental mesangial proliferative glomerulonephritis. (9808091)
1998
25
Activated mesangial cells produce vascular permeability factor in early-stage mesangial proliferative glomerulonephritis. (9773782)
1998
26
Enhanced glomerular profilin gene and protein expression in experimental mesangial proliferative glomerulonephritis. (8651905)
1996
27
Mesangial proliferative glomerulonephritis and nephrotic syndrome with hepatitis A virus infection. (9141810)
1996
28
Suppression of mesangial proliferative glomerulonephritis development in rats by inhibitors of cAMP phosphodiesterase isozymes types III and IV. (8755633)
1996
29
The novel regulatory mechanism of Fas system-mediated apoptosis in mesangial cells: implication to mesangial proliferative glomerulonephritis. (8619833)
1996
30
Endothelin 1 and cyclic guanosine monophosphate in nonimmunological progression of mesangial proliferative glomerulonephritis. (7758332)
1995
31
Idiopathic polymyositis complicated by arthritis and mesangial proliferative glomerulonephritis: case report and review of the literature. (8402004)
1993
32
Mononuclear cell subsets in IgM mesangial proliferative glomerulonephritis. A comparative study with minimal change nephrotic syndrome and immunonegative mesangial proliferative glomerulonephritis. (8247183)
1993
33
Protective role of BCG in the rabbit model of mesangial proliferative glomerulonephritis. (1956554)
1991
34
A case of IgM-associated mesangial proliferative glomerulonephritis with a giant paramesangial spherical deposit. (1798222)
1991
35
IgM-associated primary diffuse mesangial proliferative glomerulonephritis: natural history and prognostic indicators. (1852859)
1991
36
Pathogenic role of polyclonal and polymeric IgA in a murine model of mesangial proliferative glomerulonephritis with IgA deposition. (2044226)
1991
37
Clinicopathological features in patients with isolated C3 mesangial proliferative glomerulonephritis. (2129468)
1990
38
Involvement of IL-6 in mesangial proliferative glomerulonephritis. (2592764)
1989
39
Renal granuloma and mesangial proliferative glomerulonephritis in leprosy. (3221115)
1988
40
Mesangial proliferative glomerulonephritis in a patient with hepatic hydatid cysts: a case report in an African male. (3232184)
1988
41
Mesangial proliferative glomerulonephritis. Natural history and effects of dextran sulfate. (2437347)
1987
42
Effects of triple therapy on the progression of mesangial proliferative glomerulonephritis. (3549083)
1987
43
Mesangial proliferative glomerulonephritis with Legionnaires' disease. A case report. (3983750)
1985
44
Clinical features and glomerular immunofluorescence of renal biopsies from children with nephrotic syndrome due to minimal change disease and two variants of mesangial proliferative glomerulonephritis. (6370883)
1984
45
Mesangial proliferative glomerulonephritis with IgM deposits. Clinicopathologic analysis and evidence for morphologic transitions. (6382035)
1984
46
Mesangial proliferative glomerulonephritis with unusual intramembranous granular dense deposits. (6188567)
1983
47
Long term study of mesangial proliferative glomerulonephritis with IgM deposits. (7329978)
1981
48
Mesangial proliferative glomerulonephritis in mixed connective tissue disease (MCTD). (7363519)
1980
49
Mesangial proliferative glomerulonephritis with irregular intramembranous deposits. Another variant of hypocoplementemic nephritis. (331950)
1977
50
Mesangial proliferative glomerulonephritis in childhood. (4536432)
1973

Variations for Mesangial Proliferative Glomerulonephritis

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Expression for genes affiliated with Mesangial Proliferative Glomerulonephritis

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Search GEO for disease gene expression data for Mesangial Proliferative Glomerulonephritis.

Pathways for genes affiliated with Mesangial Proliferative Glomerulonephritis

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Pathways related to Mesangial Proliferative Glomerulonephritis according to GeneCards Suite gene sharing:

(show top 50)    (show all 51)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.7AGTR1, MAPK1
2
Show member pathways
9.6CCL2, CCR5, CCR1
39.6MAPK1, EDN1
49.5VEGFA, CCL2
59.5IL6, MAPK1
69.5IL6, MAPK1
79.4FGF2, VEGFA
8
Show member pathways
9.3AGTR1, EDN1, MAPK1
9
Show member pathways
9.2MAPK1, PDGFD, FGF2
10
Show member pathways
9.2CCR5, MAPK1, IL6
119.2EDN1, FGF2, MAPK1
12
Show member pathways
9.2CCL2, MAPK1, IL6
139.2MAPK1, IL6, CCL2
14
Show member pathways
Immune response Role of TLRs 3 and 4 in cell antiviral response TICAM1 specific signaling pathways59
Immune response IL 1 signaling pathway59
9.1MAPK1, IL6, EDN1
15
Show member pathways
Immune response BCR pathway59
Fc-epsilon receptor I signaling in mast cells36
9.1VEGFA, MAPK1, CD79A
16
Show member pathways
9.1CCR5, CCR1, CCL2, MAPK1
179.1VEGFA, IL6, CCL2
18
Show member pathways
Development EDNRB signaling59
Development ACM2 and ACM4 activation of ERK59
Cell adhesion Integrin inside out signaling59
Development G Proteins mediated regulation MARK ERK signaling59
Signal transduction IP3 signaling59
Development Angiotensin signaling via PYK259
Development EPO induced MAPK pathway59
9.0AGTR1, CD79A, EDN1, MAPK1
19
Show member pathways
Development VEGF signaling via VEGFR2 generic cascades59
9.0MAPK1, CCL2, VEGFA
20
Show member pathways
9.0MAPK1, EDN1, VEGFA
21
Show member pathways
Cytoskeleton remodeling FAK signaling59
Development Endothelin 1 EDNRA transactivation of EGFR59
9.0MAPK1, VEGFA, EDN1
22
Show member pathways
BCR signaling pathway36
TCR Signaling Pathway36
8.9IL6, MAPK1, CD79A, CCR5
23
Show member pathways
8.9AGTR1, EDN1, CCR1, CCL2, CCR5
248.9FGF2, MAPK1, VEGFA
258.9FGF2, MAPK1, VEGFA
26
Show member pathways
Angiogenesis36
8.9VEGFA, MAPK1, FGF2
27
Show member pathways
8.9VEGFA, MAPK1, FGF2
288.9MAPK1, VEGFA, FGF2
29
Show member pathways
Apoptosis and survival TNFR1 signaling pathway59
TWEAK Signaling Pathway36
Apoptosis Modulation by HSP7036
HIV-1 Nef- Negative effector of Fas and TNF-alpha36
8.9MAPK1, IL6, CCR5, CCL2
30
Show member pathways
8.8CD79A, IL6, FGF2, MAPK1
31
Show member pathways
8.8MAPK1, FGF2, IL6, CD79A
32
Show member pathways
8.8IL6, FGF2, MAPK1, CD79A
33
Show member pathways
8.8MAPK1, TGFB1I1, CCR5
348.8MAPK1, EDN1, IL6, CCL2
35
Show member pathways
8.7CCL2, IL6, CCR1, CCR5, FGF2
36
Show member pathways
Translation Non genomic rapid action of Androgen Receptor59
8.7TGFB1I1, MAPK1, IL6
37
Show member pathways
Signaling Pathways in Glioblastoma36
8.6VEGFA, MAPK1, FGF2, PDGFD
38
Show member pathways
8.6PDGFD, VEGFA, MAPK1, FGF2
39
Show member pathways
8.5MAPK1, CCR1, CCL2, CCR5, THY1
408.5MAPK1, EDN1, VEGFA, IL6
418.5VEGFA, IL6, MAPK1, FGF2
42
Show member pathways
8.5AGTR1, MAPK1, IL6, CCL2, FGF2
43
Show member pathways
8.5MAPK1, IL6, AGTR1, CCL2, FGF2
44
Show member pathways
IL23-mediated signaling events36
Immune response IL 10 signaling pathway59
Angiopoietin receptor Tie2-mediated signaling36
Development PDGF signaling via STATs and NF kB59
Development Angiopoietin Tie2 signaling59
8.5IL6, MAPK1, AGTR1, FGF2, CCL2
458.1FGF2, MAPK1, VEGFA, IL6, PDGFD
46
Show member pathways
7.9CCL2, FGF2, IL6, CCR1, CCR5, PTPRQ
47
Show member pathways
7.6VEGFA, CCL2, IL6, CCR5, EDN1, CCR1
48
Show member pathways
7.4CCL2, CCR5, CCR1, IL6, MAPK1, FGF2
49
Show member pathways
7.1VEGFA, PDGFD, FGF2, AGTR1, CCL2, MAPK1

Compounds for genes affiliated with Mesangial Proliferative Glomerulonephritis

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Compounds related to Mesangial Proliferative Glomerulonephritis according to GeneCards Suite gene sharing:

(show top 50)    (show all 154)
idCompoundScoreTop Affiliating Genes
1shikonin4410.0CCR1, CCR5, CCL2
2mdms449.9CCR1, CCR5, CCL2
3valsartan44 60 28 1112.8CCL2, EDN1, AGTR1
4mip 1alpha449.8CCL2, IL6, CCR5
5irbesartan44 28 50 1112.7CCL2, EDN1, AGTR1
6gw966244 2810.7MAPK1, AGTR1, CCL2
7ccl344 2810.5CCL2, CCR5, CCR1, IL6
8hcec449.5MAPK1, IL6, CCL2
98-isoprostane449.4EDN1, CCL2, IL6, AGTR1
10tpck449.4MAPK1, IL6, CCL2
11verapamil44 28 50 24 1113.3FGF2, EDN1, AGTR1, CCL2
12ro 31 8220449.3CCL2, VEGFA, MAPK1
13candesartan44 50 28 1112.2CCL2, AGTR1, VEGFA
14vitamin d449.2CCR5, IL6, CD79A, AGTR1, CCL2
15carvedilol44 50 28 1112.2AGTR1, EDN1, VEGFA
16bucillamine449.2VEGFA, CD79A, FGF2, IL6
17norepinephrine44 24 1111.1CCL2, CD79A, AGTR1, IL6, EDN1
18rosiglitazone28 44 50 24 1113.1AGTR1, MAPK1, IL6, CCL2
19histamine44 28 2411.1CCR5, CD79A, EDN1, IL6, CCL2
20tgf beta1449.1IL6, AGTR1, CCL2, FGF2
21cytochalasin d44 6010.1FGF2, MAPK1, CCR5, CCL2
22atorvastatin44 50 28 24 1113.0CCL2, IL6, VEGFA, EDN1
23triptolide448.9MAPK1, IL6, CCL2, VEGFA
24isoproterenol44 119.9FGF2, AGTR1, MAPK1, CCL2, EDN1
25simvastatin44 50 60 28 24 1113.9AGTR1, IL6, VEGFA, CCL2, CCR5
26apocynin44 609.9VEGFA, EDN1, MAPK1
27gf 109203x44 609.8EDN1, VEGFA, FGF2, MAPK1
28prostacyclin448.8CCL2, AGTR1, FGF2, EDN1, VEGFA
29suramin44 28 1110.8FGF2, AGTR1, CD79A, MAPK1, VEGFA
30cyclosporin a44 28 6010.8FGF2, EDN1, CCR5, IL6, CD79A, AGTR1
31herbimycin a44 609.8MAPK1, FGF2, CCL2, EDN1, IL6
32ang ii448.8VEGFA, EDN1, AGTR1, CCL2, MAPK1
33heparin44 28 24 1111.8VEGFA, FGF2, AGTR1, CCR1, CD79A, CCR5
34pd 98,059448.7CCL2, FGF2, MAPK1, IL6, EDN1
35alanine448.6CCR5, CCR1, IL6, AGTR1, FGF2, CD79A
3615-deoxy-delta-12,14-prostaglandin j2448.6MAPK1, VEGFA, FGF2, CCL2, IL6
37phosphatidylinositol448.5CCR1, EDN1, MAPK1, CCL2, FGF2, AGTR1
38hyaluronic acid44 249.4VEGFA, IL6, CD79A, FGF2
39ly294002448.4MAPK1, CCL2, IL6, VEGFA, FGF2
40n acetylcysteine448.4IL6, AGTR1, CD79A, MAPK1, VEGFA, CCL2
41nitric oxide44 24 1110.4CCL2, EDN1, AGTR1, MAPK1, IL6, CCR1
42estrogen448.0VEGFA, CCR5, FGF2, CD79A, IL6, MAPK1
43sb 20358044 608.9IL6, VEGFA, CCL2, MAPK1, AGTR1, FGF2
44genistein44 28 60 1 24 1112.9CCL2, MAPK1, AGTR1, IL6, VEGFA, FGF2
45cycloheximide447.7AGTR1, FGF2, EDN1, VEGFA, CCL2, CCR1
46vegf447.6IL6, MAPK1, FGF2, AGTR1, CD79A, CCL2
47dexamethasone44 50 28 1110.5CCL2, CCR5, CCR1, IL6, FGF2, MAPK1
48pge2447.4CD79A, FGF2, MAPK1, IL6, CCR1, CCR5
49actinomycin d447.4CCL2, EDN1, VEGFA, CCR5, CCR1, IL6
50tyrosine446.7TGFB1I1, VEGFA, THY1, CCR5, CCR1, IL6

GO Terms for genes affiliated with Mesangial Proliferative Glomerulonephritis

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Cellular components related to Mesangial Proliferative Glomerulonephritis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1external side of plasma membraneGO:00098978.6CD79A, IL6, CCR1, CCR5, THY1
2extracellular spaceGO:00056158.3FGF2, IL6, CCL2, VEGFA, EDN1
3extracellular regionGO:00055767.6EDN1, VEGFA, CCL2, IL6, PDGFD, FGF2

Biological processes related to Mesangial Proliferative Glomerulonephritis according to GeneCards Suite gene sharing:

(show all 43)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of monocyte chemotaxisGO:009002610.3CCR1, CCR5
2dendritic cell chemotaxisGO:000240710.3CCR5, CCR1
3positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling paGO:005148210.2AGTR1, EDN1
4maternal process involved in parturitionGO:006013710.1EDN1, CCL2
5regulation of vasoconstrictionGO:001922910.1EDN1, AGTR1
6regulation of vascular endothelial growth factor productionGO:001057410.1IL6, CCL2
7chemokine-mediated signaling pathwayGO:007009810.0CCL2, CCR1, CCR5
8negative regulation of hormone secretionGO:004688810.0IL6, EDN1
9monocyte chemotaxisGO:000254810.0CCL2, IL6
10MAPK import into nucleusGO:000018910.0FGF2, MAPK1
11calcium-mediated signalingGO:00197229.9CCR5, AGTR1, EDN1
12positive regulation of T cell activationGO:00508709.9CCL2, THY1
13regulation of angiogenesisGO:00457659.9IL6, FGF2
14B cell receptor signaling pathwayGO:00508539.8MAPK1, CD79A
15lipopolysaccharide-mediated signaling pathwayGO:00316639.8CCL2, MAPK1
16cell migration involved in sprouting angiogenesisGO:00020429.8VEGFA, FGF2
17vascular endothelial growth factor receptor signaling pathwayGO:00480109.8CCL2, VEGFA
18positive regulation of ERK1 and ERK2 cascadeGO:00703749.7IL6, FGF2, CCR1
19positive regulation of blood vessel endothelial cell migrationGO:00435369.7VEGFA, FGF2
20response to amino acidGO:00432009.7EDN1, IL6, CCL2
21positive regulation of nitric oxide biosynthetic processGO:00454299.7EDN1, IL6
22positive regulation of cytosolic calcium ion concentrationGO:00072049.7AGTR1, CCR1, CCR5, EDN1
23MAPK cascadeGO:00001659.7CCL2, CCR5, MAPK1
24response to antibioticGO:00466779.7CCL2, IL6
25positive chemotaxisGO:00509189.7VEGFA, FGF2
26cell surface receptor signaling pathwayGO:00071669.6EDN1, CCL2, CCR5, CCR1
27organ morphogenesisGO:00098879.6CCL2, MAPK1, FGF2
28cell-cell signalingGO:00072679.6EDN1, CCR1, CCR5
29G-protein coupled receptor signaling pathwayGO:00071869.6EDN1, CCL2, AGTR1, CCR5
30positive regulation of cell divisionGO:00517819.5FGF2, VEGFA, PDGFD
31inflammatory responseGO:00069549.5CCL2, CCR5, IL6, CCR1
32positive regulation of endothelial cell proliferationGO:00019389.5FGF2, VEGFA, CCL2
33cellular response to interleukin-1GO:00713479.5CCL2, EDN1
34regulation of cell shapeGO:00083609.4VEGFA, IL6, CCL2
35response to hypoxiaGO:00016669.4CCL2, VEGFA, EDN1
36cytokine-mediated signaling pathwayGO:00192219.3CCR1, CCL2, IL6
37positive regulation of cell migrationGO:00303359.3EDN1, MAPK1, VEGFA
38response to heatGO:00094089.3IL6, CCL2, TGFB1I1
39angiogenesisGO:00015259.2VEGFA, CCL2, THY1
40chemotaxisGO:00069359.1FGF2, MAPK1, CCR1, CCL2, CCR5
41platelet activationGO:00301689.0MAPK1, IL6, VEGFA
42positive regulation of transcription, DNA-templatedGO:00458938.5FGF2, MAPK1, IL6, TGFB1I1
43positive regulation of cell proliferationGO:00082848.5VEGFA, FGF2, IL6, MAPK1, EDN1

Molecular functions related to Mesangial Proliferative Glomerulonephritis according to GeneCards Suite gene sharing:

(show all 11)
idNameGO IDScoreTop Affiliating Genes
1chemokine (C-C motif) ligand 5 bindingGO:007179110.2CCR1, CCR5
2C-C chemokine bindingGO:001995710.1CCR1, CCR5
3C-C chemokine receptor activityGO:001649310.0CCR5, CCR1
4phosphatidylinositol phospholipase C activityGO:00044359.9CCR1, CCR5
5chemokine receptor activityGO:00049509.8CCR1, CCR5
6platelet-derived growth factor receptor bindingGO:00051619.6PDGFD, VEGFA
7chemoattractant activityGO:00420569.1FGF2, VEGFA
8heparin bindingGO:00082019.1VEGFA, CCL2, FGF2
9growth factor activityGO:00080838.9FGF2, PDGFD, IL6, VEGFA
10cytokine activityGO:00051258.8EDN1, VEGFA, IL6, FGF2
11protein bindingGO:00055156.1EDN1, THY1, VEGFA, TGFB1I1, CCR5, CCR1

Sources for Mesangial Proliferative Glomerulonephritis

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2CDC
12ExPASy
13FDA
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
57SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet