MCID: MSN006
MIFTS: 33

Mesenchymoma malady

Categories: Cancer diseases, Rare diseases, Nephrological diseases

Aliases & Classifications for Mesenchymoma

Aliases & Descriptions for Mesenchymoma:

Name: Mesenchymoma 12 42 14 69

Classifications:



External Ids:

Disease Ontology 12 DOID:2668
MeSH 42 D008637
NCIt 47 C3233
SNOMED-CT 64 189809007 44524009
UMLS 69 C0025464

Summaries for Mesenchymoma

MalaCards based summary : Mesenchymoma is related to malignant mesenchymoma and benign mesenchymoma. An important gene associated with Mesenchymoma is MB (Myoglobin), and among its related pathways/superpathways is Mesenchymal Stem Cell Differentiation Pathways and Lineage-specific Markers. The drugs Doxorubicin and Ifosfamide have been mentioned in the context of this disorder. Affiliated tissues include bone, liver and heart.

Related Diseases for Mesenchymoma

Diseases in the Mesenchymoma family:

Benign Mesenchymoma Malignant Mesenchymoma
Adult Malignant Mesenchymoma

Diseases related to Mesenchymoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 87)
id Related Disease Score Top Affiliating Genes
1 malignant mesenchymoma 12.1
2 benign mesenchymoma 12.0
3 childhood malignant mesenchymoma 11.8
4 adult malignant mesenchymoma 11.8
5 glaucoma iridogoniodysgenesia 10.2 DES MB
6 microsporidiosis 10.2 HMGA2 MB
7 reticulohistiocytic granuloma 10.2 DES MB
8 sensory organ benign neoplasm 10.1 HMGA2 MB
9 extracutaneous mastocytoma 10.1 DES MB
10 bone deterioration disease 10.1 DES MB
11 rectum lymphoma 10.1 HMGA2 MB
12 rectal neoplasm 10.1 DES MB
13 malignant mixed mullerian tumor 10.1 DES HMGA2
14 breast rhabdomyosarcoma 10.1 DES HMGA2
15 t-cell childhood lymphoblastic lymphoma 10.1 DES MB
16 neurofibroma 10.1 HMGA2 MB
17 house allergic alveolitis 10.1 DES HMGA2
18 van regemorter pierquin vamos syndrome 10.1 DES MB
19 brain stem infarction 10.1 MB MYOD1
20 pilar sheath acanthoma 10.1 DES HMGA2
21 endodermal sinus tumor 10.1 MB MYOD1
22 hyperpituitarism 10.1 DES MB
23 glomerulonephritis 10.1 MB MYOD1
24 ectopic pregnancy 10.1 DES MYOD1
25 testis sarcoma 10.1 DES MYOD1
26 cardiac tamponade 10.1 DES MYOD1
27 extraosseous osteosarcoma 10.1 DES MYOD1
28 lung benign neoplasm 10.0 DES MYOD1
29 pulmonary immaturity 10.0 MB MYOD1
30 enchondromatosis dwarfism deafness 10.0 DES MYOD1
31 transitional papilloma 10.0 ECM1 HMGA2
32 ectodermal dysplasia 3, witkop type 10.0 DES HMGA2
33 adenosarcoma 10.0 DES MB
34 mediastinum rhabdomyosarcoma 10.0 MB MYOD1
35 juvenile xanthogranuloma 10.0 DES MYOD1
36 extraosseous ewing's sarcoma 10.0 DES MB
37 diabetes persistent mullerian ducts 10.0 DES MYOD1
38 palmoplantar keratosis 10.0 DES HMGA2 MB
39 liposarcoma 10.0
40 sarcoma 10.0
41 cerebral angioma 10.0 MB MYOD1
42 amyloidosis, hereditary, transthyretin-related 9.9 DES HMGA2
43 mixed type rhabdomyosarcoma 9.9 DES MB MYOD1
44 verruciform xanthoma of skin 9.9 DES MB MYOD1
45 intrahepatic bile duct cystadenoma 9.9 DES MB MYOD1
46 ovarian cystadenoma 9.9 DES MB MYOD1
47 bile duct rhabdomyosarcoma 9.9 DES MB MYOD1
48 childhood medulloblastoma 9.9 DES MB MYOD1
49 spindle cell rhabdomyosarcoma 9.9 DES MB MYOD1
50 mediastinum sarcoma 9.9 DES MB MYOD1

Graphical network of the top 20 diseases related to Mesenchymoma:



Diseases related to Mesenchymoma

Symptoms & Phenotypes for Mesenchymoma

Drugs & Therapeutics for Mesenchymoma

Drugs for Mesenchymoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 52)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Doxorubicin Approved, Investigational Phase 3,Phase 2,Phase 1 23214-92-8 31703
2
Ifosfamide Approved Phase 3,Phase 2,Phase 1 3778-73-2 3690
3
Mechlorethamine Approved Phase 3,Phase 1 51-75-2 4033
4
Carboplatin Approved Phase 3,Phase 2 41575-94-4 10339178 498142 38904
5
Cyclophosphamide Approved, Investigational Phase 3,Phase 2 50-18-0, 6055-19-2 2907
6
Dactinomycin Approved Phase 3,Phase 2 50-76-0 2019 457193
7
Etoposide Approved Phase 3,Phase 2 33419-42-0 36462
8
Morphine Approved, Investigational Phase 3 57-27-2 5288826
9
Topotecan Approved, Investigational Phase 3 119413-54-6, 123948-87-8 60700
10
Vincristine Approved, Investigational Phase 3,Phase 2 2068-78-2, 57-22-7 5978
11
Vinorelbine Approved, Investigational Phase 3 71486-22-1 60780 44424639
12
Lenograstim Approved Phase 3,Phase 2 135968-09-1
13
Epirubicin Approved Phase 3,Phase 2 56420-45-2 41867
14
Irinotecan Approved, Investigational Phase 3,Phase 2 97682-44-5, 100286-90-6 60838
15
Trabectedin Approved, Investigational Phase 2, Phase 3 114899-77-3 108150
16
Mesna Approved Phase 3 3375-50-6 598
17
Doxil Approved June 1999 Phase 3,Phase 2,Phase 1 31703
18
Camptothecin Experimental Phase 3,Phase 2 7689-03-4
19 Alkylating Agents Phase 3,Phase 2,Phase 1
20 Anti-Bacterial Agents Phase 3,Phase 2,Phase 1
21 Antibiotics, Antitubercular Phase 3,Phase 2,Phase 1
22 Antineoplastic Agents, Alkylating Phase 3,Phase 2,Phase 1
23 Isophosphamide mustard Phase 3,Phase 2,Phase 1
24 Topoisomerase Inhibitors Phase 3,Phase 2,Phase 1
25 Anti-Infective Agents Phase 3,Phase 2
26 Antimitotic Agents Phase 3,Phase 2
27 Antineoplastic Agents, Phytogenic Phase 3,Phase 2
28 Antirheumatic Agents Phase 3,Phase 2
29 Etoposide phosphate Phase 3,Phase 2
30 Immunosuppressive Agents Phase 3,Phase 2
31 Nucleic Acid Synthesis Inhibitors Phase 3,Phase 2
32 topoisomerase I inhibitors Phase 3,Phase 2
33 Adjuvants, Immunologic Phase 3,Phase 1
34
Dacarbazine Approved, Investigational Phase 2 4342-03-4 5351166
35
Temozolomide Approved, Investigational Phase 2 85622-93-1 5394
36
Romidepsin Approved, Investigational Phase 2 128517-07-7 5352062
37
Sunitinib Approved, Investigational Phase 2 341031-54-7, 557795-19-4 5329102
38
Gemcitabine Approved Phase 2 95058-81-4 60750
39 Imatinib Mesylate Phase 2,Phase 1 123596
40 Protein Kinase Inhibitors Phase 2,Phase 1
41 Angiogenesis Inhibitors Phase 2,Phase 1
42 Angiogenesis Modulating Agents Phase 2,Phase 1
43 Antimetabolites Phase 2
44 Antimetabolites, Antineoplastic Phase 2
45 Antiviral Agents Phase 2
46 Protective Agents Phase 2
47 razoxane Phase 2
48 Antibodies Phase 1
49 Antibodies, Monoclonal Phase 1
50 Immunoglobulins Phase 1

Interventional clinical trials:

(show all 32)
id Name Status NCT ID Phase
1 Observation, Radiation Therapy, Combination Chemotherapy, and/or Surgery in Treating Young Patients With Soft Tissue Sarcoma Unknown status NCT00346164 Phase 3
2 Combination Chemotherapy in Treating Young Patients With Nonmetastatic Rhabdomyosarcoma Unknown status NCT00379457 Phase 3
3 Combination Chemotherapy in Treating Patients With Previously Untreated Rhabdomyosarcoma Completed NCT00003958 Phase 3
4 Combination Chemotherapy With or Without Radiation Therapy in Treating Patients With Newly Diagnosed Rhabdomyosarcoma Completed NCT00002995 Phase 3
5 Surgery With or Without Combination Chemotherapy in Treating Patients With Lung Metastases From Soft Tissue Sarcoma Completed NCT00002764 Phase 3
6 Surgery With or Without Chemotherapy in Treating Patients With Soft Tissue Sarcoma Completed NCT00002641 Phase 3
7 Surgery Followed by Chemotherapy in Treating Young Patients With Soft Tissue Sarcoma Completed NCT00002898 Phase 3
8 Surgery With or Without Radiation Therapy in Untreated Nonmetastatic Retroperitoneal Sarcoma Recruiting NCT01344018 Phase 3
9 Combination Chemotherapy and Radiation Therapy in Treating Patients With Newly Diagnosed Rhabdomyosarcoma Active, not recruiting NCT00354835 Phase 3
10 High-Dose Combination Chemotherapy and Radiation Therapy in Treating Patients With Newly Diagnosed Metastatic Rhabdomyosarcoma or Ectomesenchymoma Active, not recruiting NCT00354744 Phase 3
11 Randomised Trial of Volume of Post-operative Radiotherapy Given to Adult Patients With eXtremity Soft Tissue Sarcoma Active, not recruiting NCT00423618 Phase 3
12 Doxorubicin Hydrochloride or Trabectedin in Treating Patients With Previously Untreated Advanced or Metastatic Soft Tissue Sarcoma Terminated NCT01189253 Phase 2, Phase 3
13 Brostallicin or Doxorubicin as First-Line Therapy in Treating Patients With Relapsed, Refractory, or Metastatic Soft Tissue Sarcoma Unknown status NCT00410462 Phase 2
14 Temozolomide in Treating Patients With Advanced Soft Tissue Sarcoma Unknown status NCT00003718 Phase 2
15 Vismodegib and Gamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097 in Treating Patients With Advanced or Metastatic Sarcoma Completed NCT01154452 Phase 1, Phase 2
16 Depsipeptide (Romidepsin) in Treating Patients With Metastatic or Unresectable Soft Tissue Sarcoma Completed NCT00112463 Phase 2
17 Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Metastatic Rhabdomyosarcoma or Sarcoma Completed NCT00003955 Phase 2
18 Phase II Study of Imatinib Mesylate in Patients With Life Threatening Malignant Rare Diseases Completed NCT00154388 Phase 2
19 BI 2536 in Treating Patients With Recurrent or Metastatic Solid Tumors Completed NCT00526149 Phase 2
20 Sunitinib in Treating Patients With Metastatic, Locally Advanced, or Locally Recurrent Sarcomas Completed NCT00474994 Phase 2
21 STI571 in Treating Patients With Recurrent or Refractory Soft Tissue Sarcoma Completed NCT00006357 Phase 1, Phase 2
22 Ecteinascidin 743 in Treating Patients With Advanced Soft Tissue Sarcoma Completed NCT00003939 Phase 2
23 Combination Chemotherapy in Treating Children With Metastatic Rhabdomyosarcoma or Other Malignant Mesenchymal Tumors Completed NCT00025441 Phase 2
24 Gemcitabine Hydrochloride With or Without Pazopanib Hydrochloride in Treating Patients With Refractory Soft Tissue Sarcoma Recruiting NCT01532687 Phase 2
25 Irinotecan and Carboplatin as Upfront Window Therapy in Treating Patients With Newly Diagnosed Intermediate-Risk or High-Risk Rhabdomyosarcoma Active, not recruiting NCT00077285 Phase 2
26 Intensity-Modulated Radiation Therapy in Treating Patients Undergoing Surgery for Stage IB, Stage II, or Stage III Soft Tissue Sarcoma Terminated NCT00740597 Phase 2
27 Cixutumumab and Doxorubicin Hydrochloride in Treating Patients With Unresectable, Locally Advanced, or Metastatic Soft Tissue Sarcoma Completed NCT00720174 Phase 1
28 Liposomal Doxorubicin Plus Ifosfamide in Treating Patients With Advanced or Metastatic Soft Tissue Sarcoma Completed NCT00030784 Phase 1
29 NHS-IL12 for Solid Tumors Recruiting NCT01417546 Phase 1
30 Tissue Sample Collection From Patients With Soft Tissue Sarcoma of the Arms, Hands, Legs, or Feet Treated on Clinial Trial CRUK-VORTEX Unknown status NCT00900211
31 Studying Genes in Tissue Samples From Younger and Adolescent Patients With Soft Tissue Sarcomas Completed NCT01567046
32 Glutamine in Preventing Oral Mucositis in Patients Receiving Chemotherapy for Sarcoma Withdrawn NCT00334984

Search NIH Clinical Center for Mesenchymoma

Cochrane evidence based reviews: mesenchymoma

Genetic Tests for Mesenchymoma

Anatomical Context for Mesenchymoma

MalaCards organs/tissues related to Mesenchymoma:

39
Bone, Liver, Heart, Lung, Kidney, Breast, Tongue

Publications for Mesenchymoma

Articles related to Mesenchymoma:

(show top 50) (show all 249)
id Title Authors Year
1
Critical reappraisal of primary osseous composite sarcoma (malignant mesenchymoma) - analysis of four cases and literature review. ( 27102568 )
2016
2
Rare Head and Neck Benign Mesenchymoma in Close Proximity to Submandibular Gland in a Pediatric Patient: Case Report and Review of the Literature. ( 26064744 )
2015
3
Malignant mesenchymoma with widespread metastasis including bone marrow involvement in a dog. ( 25132008 )
2014
4
Diagnosis and treatment considerations in a case of malignant mesenchymoma in an African fur seal (Arctocephalus pusillus). ( 23805568 )
2013
5
Multidetector CT and histological features of benign mesenchymoma of the infratemporal space: a rare case report. ( 22282510 )
2013
6
Fibrocartilaginous mesenchymoma arising in the pubic bone: a case report. ( 23692424 )
2013
7
Benign mesenchymoma presenting as a paraspinal mass. ( 22535235 )
2012
8
Soft-tissue benign mesenchymoma in a pediatric patient. ( 23431526 )
2012
9
Combined cutaneous sarcoma: pleomorphic liposarcoma and conventional osteosarcoma-the so-called malignant mesenchymoma. ( 23082265 )
2012
10
Malignant mesenchymoma of the heart base in a dog with infiltration of the pericardium and metastasis to the lung. ( 22516086 )
2012
11
Congenital mesenchymoma of tibia: case report and review of literature. ( 23217910 )
2012
12
Metastatic leiomyosarcoma of the uterus with heterologous differentiation to malignant mesenchymoma. ( 22833086 )
2012
13
Congenital benign mesenchymoma on the palm. ( 22381468 )
2012
14
Fibrocartilaginous mesenchymoma, a unique osseous lesion: case report with review of the literature. ( 21560005 )
2011
15
Malignant mesenchymoma in the nasal cavity of a bull. ( 21306728 )
2011
16
Malignant mesenchymoma of the thyroid: case report and literature review. ( 20572598 )
2010
17
An intra-abdominal malignant mesenchymoma associated with nonabsorbable sutures in a ferret (Mustela putorius furo). ( 20224105 )
2010
18
Fibrocartilaginous mesenchymoma of the spine in a child: a case report. ( 20183926 )
2010
19
Malignant mesenchymoma surrounding the esophageal hiatus. ( 20103193 )
2010
20
Surgical case of giant malignant mesenchymoma in the posterior mediastinum that recurred in the bilateral mediastinum. ( 18781043 )
2008
21
Uterine malignant mesenchymoma, arising in a leiomyoma, with pulmonary metastases. ( 17257144 )
2007
22
Left atrial malignant mesenchymoma--emergency resection and mitral replacement. ( 17664193 )
2007
23
Intermandibular malignant mesenchymoma in a crossbreed dog. ( 16961475 )
2006
24
Secondary localisation of an intra-thoracic benign mesenchymoma in the fossa poplitea: a rare paediatric case. ( 16544227 )
2006
25
Benign mesenchymoma of the mediastinum: a report and review of the literature. ( 21289950 )
2006
26
Huge benign mesenchymoma in pharynx-esophagus. ( 16731171 )
2006
27
Fibrocartilagenous mesenchymoma of bone: the youngest reported case in a patient aged 1 year and 7 months. ( 15976352 )
2005
28
Benign renal mesenchymoma in the pediatric age group: a novel pathologic and karyotype entity. ( 15134997 )
2004
29
Mesenchymoma: an unusual tumour of the lip. ( 15225956 )
2004
30
Malignant mesenchymoma arising from a uterine leiomyoma in the menopause. ( 15581987 )
2004
31
Osteosarcoma with rhabdomyosarcomatous component or so-called malignant mesenchymoma of bone. ( 15792374 )
2004
32
Primary osteochondrorhabdomyosarcoma (malignant mesenchymoma) of the fibula: a rare tumour in an unusual site -- case report and review of the literature. ( 15601312 )
2004
33
Prognostic factors in the so-called malignant mesenchymoma: a clinicopathological and immunohistochemical analysis. ( 12792727 )
2003
34
Resection of a large benign pharyngo-oesophageal submucous mesenchymoma via laterocervical approach. ( 12648382 )
2003
35
Unusual renal mesenchymoma with unknown malignant potential in an infant. ( 12518350 )
2003
36
Malignant mesenchymoma of the pleura. ( 17670075 )
2003
37
Intraoral benign mesenchymoma: a report of 10 cases and review of the literature. ( 12539029 )
2003
38
Malignant mesenchymoma of the orbit: case report and review of the literature. ( 12578773 )
2003
39
Fibrocartilaginous mesenchymoma arising in the femur. ( 12009108 )
2002
40
Malignant mesenchymoma of the uterus, arising in a leiomyoma. ( 11903599 )
2002
41
Retroperitoneal malignant mesenchymoma: a case of mesenchymal mixed tumor with osteosarcoma, leiomyosarcoma, liposarcoma and fibrosarcoma. ( 12514345 )
2002
42
Radical resection of a malignant mesenchymoma with hypogastric artery transposition. ( 12210036 )
2002
43
Translocation of the HMGI-C ( HMGA2) gene in a benign mesenchymoma (chondrolipoangioma). ( 12021922 )
2002
44
Benign mesenchymoma of the tongue. ( 12402020 )
2002
45
Primary malignant mesenchymoma of the heart. ( 11788281 )
2002
46
Giant malignant mesenchymoma of the spermatic cord with bidirectional differentiation. ( 11441285 )
2001
47
Malignant mesenchymoma of the lower leg. ( 11684725 )
2001
48
Giant benign mesenchymoma of the mediastinum with unusual magnetic resonance imaging findings. ( 11716049 )
2001
49
Fibrocartilaginous mesenchymoma of the distal femur: case report and literature review. ( 11564220 )
2001
50
Cartilage and bone containing benign mesenchymoma of the thigh and popliteal fossa. ( 10894384 )
2000

Variations for Mesenchymoma

Expression for Mesenchymoma

Search GEO for disease gene expression data for Mesenchymoma.

Pathways for Mesenchymoma

Pathways related to Mesenchymoma according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1 10.61 DES MYOD1

GO Terms for Mesenchymoma

Molecular functions related to Mesenchymoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 core promoter binding GO:0001047 8.96 HMGA2 MYOD1
2 enzyme binding GO:0019899 8.8 ECM1 HMGA2 MYOD1

Sources for Mesenchymoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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