MCID: MSB002
MIFTS: 42

Mesoblastic Nephroma malady

Nephrological diseases, Cancer diseases, Rare diseases categories

Aliases & Classifications for Mesoblastic Nephroma

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Sources:
61UMLS, 10DISEASES, 44Novoseek
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Aliases & Descriptions for Mesoblastic Nephroma:

Name: Mesoblastic Nephroma 10 61
Congenital Mesoblastic Nephroma 61
 
Nephroma Mesoblastic 44


Classifications:



Summaries for Mesoblastic Nephroma

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Wikipedia:64 Congenital mesoblastic nephroma is a type of kidney tumor that is usually found before birth by... more...

MalaCards based summary: Mesoblastic Nephroma, also known as congenital mesoblastic nephroma, is related to congenital mesoblastic nephroma and wilms tumor. An important gene associated with Mesoblastic Nephroma is CTCF (CCCTC-binding factor (zinc finger protein)), and among its related pathways is Transcriptional misregulation in cancer. The compounds 2-methoxyethanol and k252a have been mentioned in the context of this disorder. Affiliated tissues include kidney, brain and liver, and related mouse phenotypes are liver/biliary system and renal/urinary system.

Related Diseases for Mesoblastic Nephroma

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Diseases in the Mesoblastic Nephroma family:

Adult Mesoblastic Nephroma Congenital Mesoblastic Nephroma

Diseases related to Mesoblastic Nephroma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 81)
idRelated DiseaseScoreTop Affiliating Genes
1congenital mesoblastic nephroma32.1NTRK3, SSX2B, ETV6, SMARCB1
2wilms tumor31.5WT1, LATS1
3clear cell sarcoma31.4IGF2, WT1
4congenital fibrosarcoma31.4ETV6
5metanephric adenoma31.2WT1
6fibrosarcoma30.9VIM, ETV6, NTRK3, MDM2
7beckwith-wiedemann syndrome30.9IGF2, WT1, CTCF
8sarcoma30.2TFE3, IGF2, SMARCB1, VIM, ETV6, MDM2
9cellular congenital mesoblastic nephroma10.8
10adult mesoblastic nephroma10.8
11hypercalcemia10.7
12classic congenital mesoblastic nephroma10.6
13polyhydramnios10.6
14neuroblastoma10.5
15hydrops fetalis10.5
16neurilemmoma10.5SMARCB1
17giant cell glioblastoma10.4MDM2
18nephrocalcinosis10.4
19renal hypertension10.4
20alveolar soft-part sarcoma10.4TFE3
21hemi 3 syndrome10.4WT1, IGF2
22embryonal rhabdomyosarcoma10.4IGF2, WT1
23silver-russell syndrome10.4CTCF, IGF2
24adrenal adenoma10.4REN, IGF2
25acute myelomonocytic leukemia10.3KMT2A, ETV6
26rhabdomyosarcoma 2, alveolar10.3MDM2, WT1
27benign breast phyllodes tumor10.3IGF2, VIM
28childhood kidney neoplasm10.3LATS1, WT1
29adenomatoid tumor10.3VIM, WT1
30sex cord-gonadal stromal tumor10.3VIM, WT1
31chondrosarcoma10.3MDM2, VIM
32epithelioid sarcoma10.3VIM, SMARCB1
33smooth muscle tumor10.3IGF2, VIM
34spindle cell sarcoma10.3VIM, NTRK3
35renal cell carcinoma10.3
36hepatitis10.3
37perinephritis10.3
38hypertrophic pyloric stenosis10.3
39paraganglioma10.3
40adenoma10.3
41disseminated intravascular coagulation10.3
42leiomyoma10.3
43oligohydramnios10.3
44pyloric stenosis10.3
45abrikosov's tumor10.3VIM, WT1
46chromosomal triplication10.3KMT2A, ETV6, CTCF
47acute myeloid leukemia, adult10.2KMT2A, NTRK3, WT1
48malignant peripheral nerve sheath tumor10.2VIM, MDM2
49adrenal cortical adenoma10.2REN, IGF2
50precursor t-cell acute lymphoblastic leukemia10.2WT1, ETV6, KMT2A

Graphical network of the top 20 diseases related to Mesoblastic Nephroma:



Diseases related to mesoblastic nephroma

Symptoms for Mesoblastic Nephroma

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Drugs & Therapeutics for Mesoblastic Nephroma

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Drug clinical trials:

Search ClinicalTrials for Mesoblastic Nephroma

Search NIH Clinical Center for Mesoblastic Nephroma

Genetic Tests for Mesoblastic Nephroma

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Anatomical Context for Mesoblastic Nephroma

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MalaCards organs/tissues related to Mesoblastic Nephroma:

31
Kidney, Brain, Liver, Bone, Heart, Lung, Testes

Animal Models for Mesoblastic Nephroma or affiliated genes

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Publications for Mesoblastic Nephroma

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Articles related to Mesoblastic Nephroma:

(show top 50)    (show all 217)
idTitleAuthorsYear
1
Congenital mesoblastic nephroma with focal anaplastic lesion. (25818639)
2015
2
Congenital mesoblastic nephroma in a premature neonate: a case report and review of literature. (24553043)
2014
3
AIRP best cases in radiologic-pathologic correlation: congenital mesoblastic nephroma. (22236896)
2012
4
Cellular congenital mesoblastic nephroma: case report. (21541470)
2011
5
Elevated levels of aldosterone in the amniotic fluid in two cases of congenital mesoblastic nephroma. (20455206)
2010
6
Imaging of congenital mesoblastic nephroma with pathological correlation. (19629463)
2009
7
Cellular mesoblastic nephroma (infantile renal fibrosarcoma): institutional review of the clinical, diagnostic imaging, and pathologic features of a distinctive neoplasm of infancy. (19629465)
2009
8
Unusual morphology in mesoblastic nephroma. (18989680)
2009
9
WT1 expression and hemihypertrophy in congenital mesoblastic nephroma. (19011477)
2008
10
Congenital mesoblastic nephroma presenting with massive hematuria and hemorrhagic shock: report of one case. (17078466)
2006
11
Prenatal diagnosis of congenital mesoblastic nephroma associated with renal hypertension in a premature child. (14678186)
2004
12
Gene expression profiling of mesoblastic nephroma and Wilms tumors--comparison and clinical implications. (15302496)
2004
13
Prenatal diagnosis of congenital mesoblastic nephroma in mid-second trimester by sonography and magnetic resonance imaging. (14634980)
2003
14
Use of sarcoma-based chemotherapy in a case of congenital mesoblastic nephroma with liver metastases. (12809924)
2003
15
Multicystic congenital mesoblastic nephroma. (11927972)
2002
16
ETV6 rearrangements in patients with infantile fibrosarcomas and congenital mesoblastic nephromas by fluorescence in situ hybridization. (11743047)
2001
17
Cytogenetic and molecular characterization of a congenital mesoblastic nephroma. (11441343)
2001
18
Diagnosis of a fetal mesoblastic nephroma by 3D-ultrasound. (11005125)
2000
19
Hyperreninemia and congenital mesoblastic nephroma: case report and review of the literature. (10792110)
2000
20
Mesoblastic nephroma: prenatal ultrasonographic and MRI features. (10755750)
2000
21
Congenital mesoblastic nephroma: A rare cause of perinatal anemia. (9931540)
1999
22
Congenital mesoblastic nephroma. (9361489)
1997
23
Classical congenital mesoblastic nephroma in an adult: a case report on an Ethiopian. (10214440)
1997
24
A novel reciprocal translocation (14;15)(q11;q24) in a congenital mesoblastic nephroma. (8630977)
1996
25
Ultrastructure of cellular congenital mesoblastic nephroma. (8883325)
1996
26
Congenital mesoblastic nephroma associated with focal and segmental sclerosis. (8587629)
1995
27
Presence or absence of trisomy 11 is correlated with histologic subtype in congenital mesoblastic nephroma. (7923083)
1994
28
Chromosome aberrations in mesoblastic nephroma. (8395771)
1993
29
Congenital mesoblastic nephroma: an immunohistochemical and lectin study. (8387953)
1993
30
Congenital mesoblastic nephroma, hemorrhagic shock, and disseminated intravascular coagulation in a newborn infant. (1851423)
1991
31
Congenital mesoblastic nephroma occurring in a solitary kidney. (2157574)
1990
32
Congenital mesoblastic nephroma: report of a case. (2556493)
1989
33
Identification of an acidic fibroblast growth factor-like activity in a mesoblastic nephroma. (2538677)
1989
34
Prenatal diagnosis of congenital mesoblastic nephroma in association with polyhydramnios. (2845674)
1988
35
Prenatal diagnosis of fetal renal mesoblastic nephroma. (3006495)
1986
36
Congenital mesoblastic nephroma study of 7 cases--report of a case of atypical mesoblastic nephroma. (2820867)
1986
37
Hypercalcemia in association with mesoblastic nephroma: report of a case and review of the literature. (3022225)
1986
38
Prenatal appearance of a mesoblastic nephroma associated with polyhydramnios. (2997303)
1985
39
Calcification and ossification in a congenital mesoblastic nephroma. (3000046)
1985
40
Mesoblastic nephromas: a study of 29 tumours from the SIOP nephroblastoma file. (2995226)
1985
41
Prenatal sonographic detection of congenital mesoblastic nephroma in a monozygotic twin pregnancy. (6317883)
1983
42
Cystic mesoblastic nephroma. (6277070)
1982
43
Therapy and outcome in 51 children with mesoblastic nephroma: a report of the National Wilms' Tumor Study. (6298397)
1982
44
Mesoblastic nephroma: radiologic-pathologic correlation of 20 cases. (6257095)
1981
45
Congenital mesoblastic nephroma presenting with primary reninism. (221639)
1979
46
Congenital mesoblastic nephroma. (189563)
1976
47
The management of benign renal tumors of infancy. Case report of a congenital mesoblastic nephroma (leiomyomatous hamartoma). (168170)
1975
48
Congenital mesoblastic nephroma of infancy. (164787)
1975
49
Congenital mesoblastic nephroma of infancy: report of a case with unusual clinical behavior. (4357122)
1973
50
Congenital mesoblastic nephroma of infancy. A report of eight cases and the relationship to Wilms' tumor. (4378178)
1967

Variations for Mesoblastic Nephroma

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Expression for genes affiliated with Mesoblastic Nephroma

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Search GEO for disease gene expression data for Mesoblastic Nephroma.

Pathways for genes affiliated with Mesoblastic Nephroma

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Pathways related to Mesoblastic Nephroma according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
17.5WT1, MDM2, SSX2B, ETV6, KMT2A, TFE3

Compounds for genes affiliated with Mesoblastic Nephroma

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Compounds related to Mesoblastic Nephroma according to GeneCards Suite gene sharing:

(show all 39)
idCompoundScoreTop Affiliating Genes
12-methoxyethanol4410.2IGF2, VIM
2k252a4410.0VIM, NTRK3
3gefitinib44 50 1111.9IGF2, VIM, MDM2
4hydrocortisone44 1 60 1112.9IGF2, VIM, REN
5b 723449.9WT1, VIM
6valine449.8VIM, IGF2, MDM2
7chloramphenicol44 1 50 1112.7IGF2, WT1, VIM
8p00001449.7MDM2, KMT2A
9forskolin44 50 1111.7WT1, IGF2, VIM, REN
10paraffin449.7VIM, MDM2, IGF2, WT1
11estradiol44 24 1111.6MDM2, REN, IGF2, VIM
12butyrate449.6VIM, WT1, IGF2
13creatinine449.6IGF2, VIM, REN, WT1
14calcitriol44 60 24 1112.6IGF2, WT1, KMT2A, REN
15steroid449.6MDM2, IGF2, REN, WT1, CTCF
16progesterone44 28 60 24 1113.5VIM, MDM2, WT1, IGF2
17cycloheximide449.5NTRK3, MDM2, VIM, IGF2
18vincristine44 50 1111.5KMT2A, VIM, WT1, MDM2
19doxorubicin44 50 1111.4WT1, MDM2, KMT2A, VIM
20actinomycin d449.4VIM, IGF2, MDM2, KMT2A
21testosterone44 60 24 1112.4WT1, MDM2, NTRK3, VIM, IGF2
22prednisolone44 28 1111.4ETV6, KMT2A, IGF2
23agar449.3MDM2, VIM, ETV6, IGF2
24indomethacin44 28 60 1112.3IGF2, VIM, REN
25zinc44 2410.3IGF2, CTCF, WT1, MDM2, KMT2A
265-aza-2deoxycytidine449.2KMT2A, VIM, MDM2, CTCF, IGF2
27aspartate449.2VIM, KMT2A, NTRK3, MDM2
28etoposide44 50 60 1112.2IGF2, MDM2, WT1, KMT2A, VIM
29dexamethasone44 50 28 1112.2MDM2, REN, VIM, IGF2
30oligonucleotide449.2IGF2, WT1, MDM2, VIM, KMT2A
31imatinib44 50 1111.2IGF2, WT1, MDM2, ETV6, NTRK3
32estrogen449.1MDM2, WT1, VIM, KMT2A, IGF2
33arginine448.9REN, WT1, MDM2, VIM, KMT2A, IGF2
34threonine448.9MDM2, WT1, LATS1, KMT2A, NTRK3
35retinoic acid44 249.6VIM, WT1, ETV6, KMT2A, IGF2, NTRK3
36vegf448.5IGF2, WT1, MDM2, VIM, ETV6, REN
37tyrosine448.2KMT2A, IGF2, ETV6, NTRK3, MDM2, WT1
38serine448.1THBS4, KMT2A, IGF2, LATS1, CTCF, WT1
39proline448.0WT1, THBS4, VIM, NTRK3, MDM2, KMT2A

GO Terms for genes affiliated with Mesoblastic Nephroma

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Cellular components related to Mesoblastic Nephroma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1nucleusGO:00056347.2SMARCB1, KMT2A, SSX2B, MEOX1, MDM2, WT1
2nucleolusGO:00057307.2CTCF, TFE3, SMARCB1, KMT2A, ETV6, MDM2

Biological processes related to Mesoblastic Nephroma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1regulation of gene expression by genetic imprintingGO:000634910.0CTCF, IGF2
2positive regulation of gene expressionGO:00106289.5NTRK3, MDM2, CTCF
3hormone-mediated signaling pathwayGO:00097559.4REN, LATS1
4regulation of transcription from RNA polymerase II promoterGO:00063579.3WT1, ETV6, SMARCB1
5positive regulation of transcription from RNA polymerase II promoterGO:00459448.0WT1, MEOX1, KMT2A, SMARCB1, IGF2, TFE3

Molecular functions related to Mesoblastic Nephroma according to GeneCards Suite gene sharing:

(show all 7)
idNameGO IDScoreTop Affiliating Genes
1insulin-like growth factor receptor bindingGO:00051599.9IGF2, REN
2scaffold protein bindingGO:00971109.8MDM2, VIM
3p53 bindingGO:00020399.6MDM2, NTRK3, SMARCB1
4transcription regulatory region DNA bindingGO:00442128.8TFE3, KMT2A, WT1, CTCF
5sequence-specific DNA bindingGO:00435658.7CTCF, WT1, MEOX1, ETV6
6sequence-specific DNA binding transcription factor activityGO:00037007.7TFE3, KMT2A, ETV6, MEOX1, WT1, CTCF
7protein bindingGO:00055156.5CTCF, THBS4, IGF2, SMARCB1, LATS1, KMT2A

Sources for Mesoblastic Nephroma

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2CDC
12ExPASy
13FDA
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
57SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet