MCID: MTH007
MIFTS: 44

Methemoglobinemia malady

Genetic diseases, Blood diseases, Rare diseases categories

Aliases & Classifications for Methemoglobinemia

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Sources:
10Disease Ontology, 47Novoseek, 12DISEASES, 65UMLS, 36MeSH, 29ICD9CM, 59SNOMED-CT, 42NCIt
See all sources

Aliases & Descriptions for Methemoglobinemia:

Name: Methemoglobinemia 10 47 12 65 36


Classifications:



External Ids:

Disease Ontology10 DOID:10783
ICD9CM29 289.7
NCIt42 C34817
MeSH36 D008708

Summaries for Methemoglobinemia

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Wikipedia:68 Methemoglobinemia (or methaemoglobinaemia) is a disorder characterized by the presence of a higher than... more...

MalaCards based summary: Methemoglobinemia is related to malaria and congenital methemoglobinemia. An important gene associated with Methemoglobinemia is CYB5R3 (Cytochrome B5 Reductase 3), and among its related pathways are Folate Metabolism and Caffeine Pathway, Pharmacokinetics. The drugs ascorbic acid and methylene blue have been mentioned in the context of this disorder. Affiliated tissues include kidney, lung and heart, and related mouse phenotypes are liver/biliary system and cardiovascular system.

Related Diseases for Methemoglobinemia

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Diseases in the Methemoglobinemia family:

Methemoglobinemia, Type Iv Methemoglobinemia, Type I
Congenital Methemoglobinemia Hereditary Methemoglobinemia, Recessive
Autosomal Recessive Congenital Methemoglobinemia Recessive Hereditary Methemoglobinemia Type 1
Recessive Hereditary Methemoglobinemia Type 2 Hereditary Methemoglobinemia
Autosomal Dominant Methemoglobinemia

Diseases related to Methemoglobinemia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 281)
idRelated DiseaseScoreTop Affiliating Genes
1malaria29.5G6PD, GSR, HBB, HP
2congenital methemoglobinemia10.8
3methemoglobinemia, type i10.6
4hereditary methemoglobinemia10.6
5methemoglobinemia beta-globin type10.5
6autosomal recessive congenital methemoglobinemia10.5
7methemoglobinemia, type iv10.4
8hemolytic anemia10.4
9glucose-6-phosphate dehydrogenase deficiency10.3
10sulfhemoglobinemia10.3
11leukemia10.3
12diarrhea10.2
13autosomal dominant methemoglobinemia10.2
14proximal renal tubular acidosis10.2HBB, HBG2
15recurrent infections - inflammatory syndrome due to zinc metabolism disorder10.2HBB, HBG2
16fetal hemoglobin quantitative trait locus 110.2HBB, HBG2
17pneumonia10.2
18hereditary methemoglobinemia, recessive10.2
19recessive hereditary methemoglobinemia type 110.2
20recessive hereditary methemoglobinemia type 210.2
21trichinosis10.1CYB5A, GSR
22hereditary thrombophilia due to congenital protein s deficiency10.1CYB5A, CYB5R3, HBG2
23pyruvate kinase deficiency10.1G6PD, HBG2
24leprosy10.1
25burkitt lymphoma10.1
26burns10.1
27lymphoblastic leukemia10.1
28rheumatic fever10.1G6PD, HBB
29perinatal necrotizing enterocolitis10.1G6PD, GSR
30headache10.1GSR, SOD1
31snyder-robinson syndrome10.1G6PD, HBB, HBG2
32hemoglobin h disease, nondeletional10.0G6PD, HBB, HBG2
33sickle cell anemia10.0G6PD, HBB, HBG2
34ataxia10.0GSR, SOD1
35thalassemia, hispanic gamma-delta-beta10.0G6PD, HBB, HBG2
36neonatal period electroclinical syndrome10.0G6PD, HBG2
37thromboangiitis obliterans10.0G6PD, HBB, HBG2
38immunodeficiency, centromere instability and facial anomalies syndrome10.0G6PD, SOD1
39leukemia, acute myelomonocytic, somatic, somatic10.0
40hodgkin lymphoma10.0
41myelodysplastic syndrome10.0
42leukemia, acute myeloid10.0
43aplastic anemia10.0
44bone marrow failure syndrome 110.0
45leukemia, acute lymphoblastic10.0
46leukemia, chronic myeloid, somatic10.0
47child syndrome10.0
48deficiency anemia10.0
49acute leukemia10.0
50acute lymphoblastic leukemia, childhood10.0

Graphical network of the top 20 diseases related to Methemoglobinemia:



Diseases related to methemoglobinemia

Symptoms for Methemoglobinemia

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Drugs & Therapeutics for Methemoglobinemia

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Drugs for Methemoglobinemia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 22)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Nitric OxideapprovedPhase 354010102-43-9145068
Synonyms:
(.)NO
(NO)(.)
10102-43-9
14332-28-6
295566_ALDRICH
51005-20-0
51005-21-1
53851-19-7
90452-29-2
AC1L1ADQ
AC1L3QHF
AC1Q6QZ0
AR-1K7463
Bioxyde d'azote
Bioxyde d'azote [French]
C00533
CCRIS 4319
CHEMBL1200689
CHEMBL1234765
CID145068
CID945
D00074
D009569
DB00435
EDRF
EINECS 233-271-0
Endogenous Nitrate Vasodilator
Endothelium-Derived Nitric Oxide
HNO
HSDB 1246
INOmax
INOmax (TN)
Inomax
LS-192158
LS-7547
MolPort-003-929-452
Mononitrogen monoxide
Monoxide, Mononitrogen
Monoxide, Nitrogen
Monoxido de nitrogeno
Monoxyde d'azote
NITRIC-OXIDE
NO
NO(.)
Nitrate Vasodilator, Endogenous
Nitric Oxide, Endothelium Derived
 
Nitric Oxide, Endothelium-Derived
Nitric oxide
Nitric oxide (JAN)
Nitric oxide 10% by volume or more
Nitric oxide trimer
Nitric oxide, compressed [UN1660] [Poison gas]
Nitric oxide, compressed [UN1660] [Poison gas]
Nitrogen monoxide
Nitrogen oxide
Nitrogen oxide (NO)
Nitrogen protoxide
Nitrosyl
Nitrosyl hydride
Nitrosyl hydride ((NO)H)
Nitrosyl radical
Nitroxide radical
Nitroxyl
OHM 11771
Oxide, Nitric
Oxido de nitrogeno(ii)
Oxido nitrico
Oxyde azotique
Oxyde nitrique
Oxyde nitrique [French]
RCRA waste no. P076
Stickmonoxyd
Stickmonoxyd [German]
Stickstoff(II)-oxid
Stickstoff(ii)-oxid
Stickstoffmonoxid
UN 1660
UN1660
UNII-31C4KY9ESH
Vasodilator, Endogenous Nitrate
[NO]
endothelium-derived relaxing factor
monoxido de nitrogeno
monoxyde d'azote
nitric oxide
nitrogen monooxide
nitrogen monoxide
nitrosyl
oxido de nitrogeno(II)
oxido nitrico
oxidonitrogen(.)
oxoazanyl
oxyde azotique
2
PrimaquineapprovedPhase 15890-34-64908
Synonyms:
()-Primaquine
(+)-N4-(6-Methoxy-8-quinolinyl)-1,4-pentanediamine
(+)-Primaquine
(+/-)-Primaquine
(-)-N4-(6-Methoxy-8-quinolinyl)-1,4-pentanediamine
(-)-Primaquine
1,4-Pentanediamine, N4-(6-methoxy-8-quinolinyl)- (9CI)
4-22-00-05817 (Beilstein Handbook Reference)
4-N-(6-methoxyquinolin-8-yl)pentane-1,4-diamine
6-Methoxy-8-(4-amino-1-methylbutylamino)quinoline
6-Methoxy-8-[(4-amino-1-methylbutyl)amino]quinoline
6-Methoxy-8-[4-amino-1-methylbutylamino]quinoline
63-45-6
63-45-6 (1:2 PO4)
8-((4-Amino-1-methylbutyl)amino)-6-methoxyquinoline
8-(4-Amino-1-m
8-(4-Amino-1-methylbutylamino)-6-methoxyquinoline
8-[(4-Amino-1-methylbutyl)amino]-6-methoxyquinoline
90-34-6
AB00053529
AC1L1J80
AC1Q4F0C
AC1Q4F4Q
BPBio1_000674
BRN 0019337
BSPBio_000612
BSPBio_002223
C07627
CCRIS 4109
CHEBI:8405
CHEMBL506
CID4908
D08420
DB01087
DivK1c_000806
EINECS 201-987-2
HMS2090J17
HSDB 6516
I08-0048
IDI1_000806
KBio1_000806
KBio2_001310
KBio2_003878
KBio2_006446
KBio3_001723
KBioGR_000967
KBioSS_001310
Kanaprim
Kanaprim (TN)
LS-141312
MolPort-001-794-628
N(4)-(6-methoxyquinolin-8-yl)pentane-1,4-diamine
 
N-(5-aminopentan-2-yl)-6-methoxyquinolin-8-amine
N4-(6-Methoxy-8-quinolinyl)-1,4-pentanediamine
NCGC00178754-01
NCGC00178754-02
NCI60_001035
NCI60_005887
NINDS_000806
NSC 27296
NSC27296
Neo-Quipenyl
Neo-quipenyl
N~4~-[6-(methyloxy)quinolin-8-yl]pentane-1,4-diamine
Oprea1_546209
PQ
PRIMAQUINE
Prestwick0_000476
Prestwick1_000476
Prestwick2_000476
Prestwick3_000476
Primachin
Primachina
Primachina [DCIT]
Primachinum
Primaquin
Primaquina
Primaquina [INN-Spanish]
Primaquine (INN)
Primaquine Bis-Phosphoric Acid
Primaquine Phosphate
Primaquine [INN:BAN]
Primaquinum
Primaquinum [INN-Latin]
Quinoline, 8-(4-amino-1-methylbutylamino)-6-methoxy
Quinoline, 8-[(4-amino-1-methylbutyl)amino]-6-methoxy- (6CI,8CI)
S. N. 13272
SMP1_000263
SN 13,272
SN 13272
SPBio_000674
SPBio_002551
STOCK5S-90838
Spectrum2_000887
Spectrum3_000552
Spectrum4_000484
Spectrum5_001363
Spectrum_000830
TG1-296
TG1-297
UNII-MVR3634GX1
WLN: T66 BNJ HO1 JMY1&3Z
WR 2975
dl-Primaquine
ethylbutylamino)-6-methoxyquinoline
3
Dapsoneapproved, investigationalPhase 16180-08-02955
Synonyms:
(4-sulfanilylphenyl)amine
1,1'-Sulfonylbis(4-aminobenzene)
1,1'-Sulfonylbis[4-aminobenzene]
1,1'-Sulphonylbis(4-aminobenzene)
1358F
32960_FLUKA
4,4' Diaminophenyl Sulfone
4,4'-Dapsone
4,4'-Diaminodiphenyl sulfone
4,4'-Diaminodiphenyl sulphone
4,4'-Diaminodiphenyl suphone
4,4'-Diaminodiphenylsulfone
4,4'-Sulfonylbisaniline
4,4'-Sulfonylbisbenzamine
4,4'-Sulfonylbisbenzenamine
4,4'-Sulfonylbisbenzeneamine
4,4'-Sulfonyldianilin
4,4'-Sulfonyldianiline
4,4'-Sulfonyldianiline (Dapsone)
4,4'-Sulphonylbisbenzamine
4,4'-Sulphonylbisbenzenamine
4,4'-Sulphonyldianiline
4,4'-diaminophenyl sulfone
4,4'-sulfonyldianiline
4,4-Diaminodifenylsulfon
4,4-Diaminodifenylsulfon [Czech]
4,4-Sulfonyldianiline
4-(4-Aminophenylsulfonyl)aniline
4-(4-Aminophenylsulfonyl)benzenamine
4-(4-amino-Benzenesulfonyl)-phenylamine
4-(4-aminophenyl)sulfonylaniline
4-Aminop henyl sulfone
4-Aminophenyl sulfone
4-Aminophenylsulfone
4-[(4-aminobenzene)sulfonyl]aniline
4-[(4-aminophenyl)sulfonyl]aniline
46158_FLUKA
46158_RIEDEL
80-08-0
A74807_ALDRICH
AB00051962
AB1004833
AC-10922
AC1L1EUH
AC1Q51WM
AC1Q51WN
AI3-08087
AKOS000119322
ALBB-005917
AZT + Dapsone cominbation
Acedapsone
Aczone
Aczone (TN)
Ambap80-08-0
Araldite HT
Araldite HT 976
Araldite Ht
Atrisone
Avlosulfon
Avlosulfone
Avlosulphone
Avsulfor
BIDD:GT0770
BPBio1_000143
BRD-K62363391-001-05-8
BRN 0788055
BSPBio_000129
BSPBio_002129
Bis(4-aminophenyl) sulfone
Bis(4-aminophenyl)sulfone
Bis(4-aminophenyl)sulphone
Bis(P-aminophenyl) sulfone
Bis(p-aminophenyl) sulfone
Bis(p-aminophenyl)sulphone
C07666
CAS-80-08-0
CBDivE_013582
CCRIS 192
CHEBI:4325
CHEMBL1043
CID2955
CPD000059064
Croysulfone
Croysulphone
D SS
D003622
D00592
D0089
DADPS
DAPSONE
DB00250
DDS
DDS (pharmaceutical)
DDS, diaphenylsulfone
DDS, pharmaceutical
DIAPHENYLSULFONE
DSS
DSS (VAN)
Dapsoderm-X
Dapson
Dapson-Fatol
Dapsona
Dapsona [INN-Spanish]
Dapsone
Dapsone (USP)
Dapsone [USAN:BAN]
Dapsonum
Dapsonum [INN-Latin]
Dds, Diaphenylsulfone
Dds, Pharmaceutical
Di(4-aminophenyl) sulfone
Di(4-aminophenyl)sulfone
Di(4-aminophenyl)sulphone
Di(p-aminophenyl) sulfone
Di(p-aminophenyl)sulphone
Diamino-4,4'-diphenyl sulfone
Diamino-4,4'-diphenyl sulphone
Diamino-diphenyl sulphone
Diaminodifenilsulfona
Diaminodifenilsulfona [Spanish]
Diaminodiphenyl Sulfone
Diaminodiphenyl sulfone
Diaminodiphenylsulfone
Diaphenylsulfon
 
Diaphenylsulfone
Diaphenylsulfone (JAN)
Diaphenylsulphon
Diaphenylsulphone
Dimitone
Diphenasone
Diphone
Disulone
DivK1c_000573
Dubronax
Dubronaz
Dumitone
EINECS 201-248-4
Eporal
F 1358
Fatol Brand of Dapsone
HMS1568G11
HMS1920C14
HMS2091K04
HMS501M15
HSDB 5073
HT 976
HY 976
Hardener HT 976
I01-3640
ICI
IDI1_000573
IN-201
KBio1_000573
KBio2_001368
KBio2_003936
KBio2_006504
KBio3_001349
KBioGR_000900
KBioSS_001368
LS-1790
MLS000069409
MLS001055349
MLS001076146
Metabolite C
Mex-America Brand of Dapsone
MolPort-001-780-172
N, N'-Diphenyl Sulfondiamide
N, N'-Diphenyl sulfondiamide
N,N'-Diphenyl sulfondiamide
NCGC00016322-01
NCGC00016322-02
NCGC00023946-03
NCGC00023946-04
NCGC00023946-05
NCGC00023946-06
NCI-C01718
NINDS_000573
NSC 6091
NSC 6091D
NSC-6091
NSC6091
Normet
Novophone
Oprea1_143052
Orsade Brand of Dapsone
P, P'-Sulfonyldianiline
P,P'-Diaminodiphenyl Sulfone
P,P'-diaminodiphenyl sulfone
P,P-Diaminodiphenyl Sulphone
P,P-Sulfonylbisbenzamine
P,P-Sulfonylbisbenzenamine
P,P-Sulphonylbisbenzamine
P,P-Sulphonylbisbenzenamine
P,P-Sulphonyldianiline
P-Aminophenyl Sulfone
P-Aminophenyl sulfone
Prestwick0_000035
Prestwick1_000035
Prestwick2_000035
Prestwick3_000035
Prestwick_152
Protogen
Recolip
SAM002554879
SMR000059064
SPBio_001025
SPBio_002050
SPECTRUM1500222
STK387118
Spectrum2_001133
Spectrum3_000375
Spectrum4_000310
Spectrum5_000825
Spectrum_000888
Sulfadione
Sulfanona-Mae
Sulfanona-mae
Sulfon-Mere
Sulfon-mere
Sulfona
Sulfona-MAE
Sulfona-Mae
Sulfone Ucb
Sulfone ucb
Sulfone, 4,4'-Diaminophenyl
Sulfonyldianiline
Sulphadione
Sulphon-Mere
Sulphon-mere
Sulphonyldianiline
Sumicure S
TL8005401
Tarimyl
UNII-8W5C518302
Udolac
W R 448
WLN: ZR DSWR DZ
WR 448
ZINC00006310
dapsone
p, p'-Sulfonyldianiline
p,p'-Diaminodiphenyl sulfone
p,p'-sulfonyldianiline
p,p-Diaminodiphenyl sulphone
p,p-Sulfonylbisbenzamine
p,p-Sulfonylbisbenzenamine
p,p-Sulphonylbisbenzamine
p,p-Sulphonylbisbenzenamine
p,p-Sulphonyldianiline
p-Aminophenyl sulfone
4
Folic Acidapproved, nutraceuticalPhase 1285159-30-36037
Synonyms:
(2S)-2-[[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
01769_FLUKA
2d0k
33609-88-0
36653-55-1 (mono-potassium salt)
59-30-3
6484-89-5 (mono-hydrochloride salt)
AC-11682
AC1L1LNX
AI3-26387
AKOS000503224
ARONIS014410
Acfol (Spain)
Acide folique
Acide folique [INN-French]
Acido folico
Acido folico [INN-Spanish]
Acidum folicum
Acidum folicum [INN-Latin]
Acifolic
Antianemia factor
Apo-Folic
BIDD:ER0563
BIDD:GT0641
BIF0608
BPBio1_000654
BSPBio_000594
BSPBio_002338
C00504
C20H20N6O6
CAS-59-30-3
CCRIS 666
CHEBI:27470
CHEMBL1622
CID6037
CPD000471860
Cytofol
D00070
DB00158
DivK1c_000494
Dosfolat B activ
EINECS 200-419-0
F0043
F7876_SIAL
F7876_SIGMA
F8758_SIGMA
F8798_SIAL
F8890_SIGMA
FOL
Facid
Factor U
Folacid
Folacin
Folaemin
Folaemin [Netherlands]
Folan
Folasic (Australia)
Folate
Folbal
Folcidin
Folcidin (VAN)
Folcysteine
Foldine
Foldine [France]
Folettes
Foliamin
Folic
Folic Acid
Folic acid
Folic acid (JP15/USP/INN)
Folic acid (TN)
Folic acid [BAN:INN:JAN]
Folic acid [INN:BAN:JAN]
Folic acid dihydrate
Folicet
Folicet (TN)
Folico
Folico (Italy)
Folina
Folina (Italy)
Folipac
 
Folsaeure
Folsan
Folsaure
Folsav
Folvite
Folvron
Glutamic acid, N-(p-(((2-amino-4-hydroxypyrimido(4,5-b)pyrazin-6-yl)methyl)amino)benzoyl)-, L
HMS1921D20
HMS2092N17
HMS501I16
HSDB 2002
IDI1_000494
InChI=1/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s
Incafolic
KBio1_000494
KBio2_001861
KBio2_004429
KBio2_006997
KBio3_001558
KBioGR_002222
KBioSS_001861
Kyselina listova
Kyselina listova [Czech]
LS-2157
Liver Lactobacillus casei factor
MLS001304016
MLS001335861
Millafol
Mission prenatal
Mittafol
MolPort-004-285-551
N-(4-(((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzo- yl)-L-glutamic acid
N-(4-((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-(4-{[(2-Amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(p-(((2-Amino-4-hydroxy-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-Pteroyl-L-glutamic acid
N-[(4-{[(2-Amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[4-[[(2-Amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid
NCGC00016265-01
NCGC00142391-01
NINDS_000494
NSC 3073
Nifolin
Nifolin [Denmark]
Novofolacid
Novofolacid [Canada]
PGA
PGA (VAN)
Prestwick3_000627
Prestwick_230
PteGlu
Pteroyl-L-glutamate
Pteroyl-L-glutamic acid
Pteroyl-L-monoglutamate
Pteroyl-L-monoglutamic acid
Pteroylglutamate
Pteroylglutamic acid
Pteroylmonoglutamate
Pteroylmonoglutamic acid
SAM002264616
SDCCGMLS-0066738.P001
SMP2_000137
SMR000471860
SPBio_001357
SPECTRUM1502020
Serum Folate Level
Spectrum2_001459
Spectrum3_000749
Spectrum4_001751
Spectrum5_000602
Spectrum_001381
UNII-935E97BOY8
Usaf cb-13
Vitamin B11
Vitamin B9
Vitamin Bc
Vitamin Be
Vitamin M
bmse000299
folic acid
nchembio.108-comp10
5Vitamin B ComplexPhase 12775
6
methylene bluePhase 167
Synonyms:
Urolene Blue
aniline violet
 
methylthionine chloride
methylthioninium chloride
methylthioninium chloride Proveblue
tetrametylthionine chloride
7Vitamin B9NutraceuticalPhase 12851
8Folinic AcidNutraceuticalPhase 12498
9FolateNutraceuticalPhase 12851
10
Prilocaineapproved62721-50-64906
Synonyms:
2-(Propylamino)-O-propionotoluidide
2-(Propylamino)-o-propionotoluidide
2-Methyl-.alpha.-propylaminopropionanilide
2-Methyl-alpha-propylaminopropionanilide
721-50-6
AB00053665
AC-2100
AC1L1J7W
Ambap1786-81-8
Astra 1512
Astra 1515
BPBio1_000173
BRD-A53952395-003-05-3
BRN 2108498
BSPBio_000157
BSPBio_002604
C07531
C13H20N2O
CHEBI:8404
CHEMBL1194
CID4906
Citanest
D00553
DB00750
DivK1c_000846
EINECS 211-957-0
HSDB 3386
I01-1860
IDI1_000846
KBio1_000846
KBio2_002129
KBio2_004697
KBio2_007265
KBio3_001824
KBioGR_001883
KBioSS_002129
L 67
LS-2304
Lopac0_001005
MolPort-005-935-583
N-(2-Methylphenyl)-2-(propylamino)propanamide
 
N-(2-methylphenyl)-N(2)-propylalaninamide
N-(2-methylphenyl)-N2-propylalaninamide
N-[2-Methylphenyl]-2-[propylamino]propanamide
NCGC00015860-03
NCGC00162312-01
NINDS_000846
NSC 40027
NSC40027
O-Methyl-2-propylaminopropionanilide
O-Methyl-alpha-propylaminopropionanilide
Prestwick0_000199
Prestwick1_000199
Prestwick2_000199
Prestwick3_000199
Prilocain
Prilocaina
Prilocaina [INN-Spanish]
Prilocaine (USP/INN)
Prilocaine Hydrochloride
Prilocaine [USAN]
Prilocaine base
Prilocainum
Prilocainum [INN-Latin]
Prilocaïne
Propanamide, N-(2-methylphenyl)-2-(propylamino)- (9CI)
Propitocaine
Propitocaine (JAN)
S1619_Selleck
SPBio_001398
SPBio_002078
Spectrum2_001549
Spectrum3_001052
Spectrum4_001192
Spectrum5_001175
Spectrum_001649
UNII-046O35D44R
alpha-N-Propylamino-2-methylpropionanilide
alpha-n-Propylamino-2-methylpropionanilide
o-Methyl-2-propylaminopropionanilide
o-Methyl-alpha-propylaminopropionanilide
prilocaine
prilocaine base
11
Epinephrineapproved76851-43-45816
Synonyms:
(-)-(R)-Epinephrine
(-)-3,4-Dihydroxy-a-[2-(methylamino)ethyl]benzyl alcohol
(-)-3,4-Dihydroxy-alpha-((methylamino)methyl)benzyl alcohol
(-)-3,4-Dihydroxy-alpha-[2-(methylamino)ethyl]benzyl alcohol
(-)-3,4-dihydroxy-a-[(methylamino)methyl]-Benzyl alcohol
(-)-3,4-dihydroxy-alpha-[(methylamino)methyl]-Benzyl alcohol
(-)-Adrenalin
(-)-Adrenaline
(-)-Epinephrine
(-)-R-Epinephrine
(R)-(-)-Adnephrine
(R)-(-)-Adrenaline
(R)-(-)-Epinephrine
(R)-(-)-Epirenamine
(R)-(−)-adrenaline
(R)-4-[1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol
(R)-4-[1-hydroxy-2-(methylamino)ethyl]-1,2-Benzenediol
(R)-Adrenaline
(R)-Epinephrine
(−)-adrenaline
02252_FLUKA
1-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol
1-Adrenalin
1-Epinephrine
4-(1-Hydroxy-2-(methylamino)ethyl)-1,2-benzenediol
4-(1-hydroxy-2-methylamino-ethyl)benzene-1,2-diol
4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-1,2-Benzenediol
4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol
4-[(1R)-1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol
51-43-4
51-43-4 (FREE BASE)
51028-73-0
A0173
AC-13188
AC1L1L7B
ADR ADRENALINE
ADROP
AI3-19015
Adnephrine
Adrenaclick
Adrenal
Adrenalin
Adrenalin (TN)
Adrenalin in Oil
Adrenalin-Medihaler
Adrenalina
Adrenalina [DCIT]
Adrenaline
Adrenaline (JP15)
Adrenaline/Epinephrine
Adrenalinum
Adrenamine
Adrenan
Adrenapax
Adrenasol
Adrenatrate
Adrenine
Adrenodis
Adrenohorma
Adrenosan
Adrenutol
Adrin
Adrine
Ana-Guard
Ana-Kit
Antiasthmatique
Asmatane Mist
Asthma meter mist
Asthma-nefrin
Asthmahaler Mist
Asthmanefrin
Astmahalin
Astminhal
Auvi-q
BIDD:GT0119
Balmadren
Bernarenin
Biorenine
Bosmin
Brevirenin
Bronkaid
Bronkaid Mist
Bronkaid Suspension Mist
Bupivacaine Hcl and Epinephrine
C00788
CCRIS 4812
CHEBI:28918
CHEMBL679
CID5816
Chelafrin
Citanest Forte
Corisol
D-Epifrin
D-Epinephrine
D00095
DB00668
Drenamist
Dylephrin
Dyspne-Inhal
E4250_SIGMA
EINECS 200-098-7
EPI E Z PEN JR
EPIPEN E Z PEN
EPIPEN JR
Epi EZ Pen Jr
Epifrin
Epiglaufrin
Epinefrin
Epinefrin [Czech]
Epinefrina
Epinefrina [INN-Spanish]
Epinephran
Epinephrin
Epinephrine
Epinephrine (USP)
Epinephrine (USP/INN)
Epinephrine [USAN:INN:JAN]
Epinephrine bitartrate
Epinephrine chloride
Epinephrine hydrochloride
Epinephrinum
Epinephrinum [INN-Latin]
Epipen
Epipen (TN)
Epipen Auto-Injector
Epipen EZ Pen
Epipen Jr
Epipen Jr.
Epipen Jr. Auto-Injector
Epipen jr
Epirenamine
Epirenan
Epirenin
Epitrate
Eppy
 
Esphygmogenina
Exadrin
Glaucon
Glaucosan
Glauposine
Glycirenan
HSCI1_000215
HSDB 4289
Haemostasin
Haemostatin
Hektalin
Hemisine
Hemostasin
Hemostatin
Hypernephrin
Hyporenin
IOP
Intranefrin
Iontocaine
Isoptoepinal
Kidoline
L-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol
L-Adrenaline
L-Adrenaline Base
L-Epinehphrine
L-Epinephrine
L-Epirenamine
L-Methylaminoethanolcatechol
L-epinephrine
LS-156
Levo-Methylaminoethanolcatechol
Levoadrenaline
Levoepinephrine
Levorenen
Levorenin
Levorenine
Levoreninum
Lopac-E-4642
Lyodrin
Lyophrin
Medihaler-Epi
Metanephrin
Methylaminoethanolcatechol
Methylarterenol
Micronefrin
Micronephrine
MolPort-002-051-368
Mucidrina
Myosthenine
Mytrate
NCGC00015417-01
NCGC00142615-01
NCGC00142615-03
NCGC00142615-04
NCGC00142615-05
NCGC00142615-06
NCGC00142615-07
NSC 62786
NSC62786
Nephridine
Nieraline
PDSP1_001120
PDSP2_001104
Paranephrin
Primatene
Primatene Mist
Primatene Mist Refill
Prime Asthma Relief
R-(-)-Epinephrine
R-Adrenaline
RCRA waste no. P042
Racemic Epinephrine
Racepinephrine
Rcra waste number P042
Renagladin
Renaglandin
Renaglandulin
Renaleptine
Renalina
Renoform
Renostypricin
Renostypticin
Renostyptin
SMP1_000227
ST069368
SUS-PHRINE SULFITE-FREE
Scurenaline
Septocaine
Simplene
Sindrenina
Soladren
Sphygmogenin
Stryptirenal
Styptirenal
Supracapsulin
Supradin
Supranefran
Supranephrane
Supranephrine
Supranol
Suprarenaline
Suprarenin
Suprel
Surenine
Surrenine
Sus-Phrine
Sus-phrine
Susphrine
Sympathin I
Takamina
Takamine
Tokamina
Tonogen
Twinject
Twinject 0.15
Twinject 0.3
Twinject 0.30
UNII-YKH834O4BH
Vaponefrin
Vasoconstrictine
Vasoconstrictor
Vasodrine
Vasoton
Vasotonin
adrenaline
bmse000316
d-Adrenaline
epinephrine
l-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol
l-Adrenalin
l-Adrenaline
l-Epinephine
l-Epinephrine (synthetic)
l-Epirenamine
l-Methylaminoethanolcatechol
levoepinephrine
nchembio747-comp9
12
Lidocaineapproved991137-58-63676
Synonyms:
.alpha.-(Diethylamino)-2,6-acetoxylidide
.alpha.-Diethylamino-2,6-dimethylacetanilide
.alpha.-Diethylaminoaceto-2,6-xylidide
.omega.-Diethylamino-2,6-dimethylacetanilide
137-58-6
2-(Diethylamino)-2',6'-acetoxylidide
2-(Diethylamino)-N-(2,6-dimethylphenyl)acetamide
2-Diethylamino-N-(2,6-dimethyl-phenyl)-acetamide
2-Diethylamino-N-(2,6-dimethylphenyl)acetamide
4-12-00-02538 (Beilstein Handbook Reference)
6108-05-0 (MONOHYDROCHLORIDE MONOHYDRATE))
6108-05-0 (mono-hydrochloride, mono-hydrate)
73-78-9 (mono-hydrochloride)
AB00053581
AC-10282
AC1L1GGQ
AC1Q2Z7J
AKOS001026768
ARONIS23855
After Burn Double Strength Gel
After Burn Double Strength Spray
After Burn Gel
After Burn Spray
Afterburn
Akten
Alphacaine
Anestacon
Anestacon Jelly
BIDD:GT0342
BPBio1_000197
BRD-K52662033-001-02-6
BRD-K52662033-003-05-5
BRN 2215784
BSPBio_000179
BSPBio_001359
BSPBio_003004
Bikini Zone Medicated
Bikini Zone Medicated Creme
Bio-0767
Bio-scriptives Lidum
Bio-scriptives Lidum Hemorroidal (anorectal)
Bio-scriptives Lidum Topical Analgesic
Bio1_000379
Bio1_000868
Bio1_001357
Bio2_000079
Bio2_000559
Burn Relief Leader
C07073
C14H22N2O
CAS-73-78-9
CDS1_000283
CHEBI:6456
CHEMBL79
CID3676
CPD000058189
Cappicaine
Cito optadren
Comfortcaine
Cuivasil
Curacaine Transdermal Corporation
D00358
DB00281
Dalcaine
Dentipatch
Dentipatch (TN)
Derma Numb
DermaFlex
Desert Harvest Releveum
Diethylaminoaceto-2,6-xylidide
Dilocaine
DivK1c_000174
DivK1c_001323
Dr. Numb
Dr. Richs Numbing
Duncaine
EINECS 205-302-8
ELA-Max
EMBOLEX
Emla
Emla Cream
Esracaine
FT-0082378
Gigi Anesthetic Numbing
Gravocain
H-releve Hemorrhoidal
HMS1791D21
HMS1989D21
HMS2051C21
HMS2089E15
HMS548M19
HSDB 3350
Hawaiian Tropic
Hush Anesthetic
I01-2704
IDI1_000174
IDI1_033829
Isicaina
Isicaine
Jetocaine
KBio1_000174
KBio2_000079
KBio2_001598
KBio2_002647
KBio2_004166
KBio2_005215
KBio2_006734
KBio3_000157
KBio3_000158
KBio3_002224
KBioGR_000079
KBioGR_000599
KBioSS_000079
KBioSS_001598
L-Caine
L0156
L1026_SIGMA
L7757_SIGMA
LIDOCAINE (73-58-6 (MONOHYDROCHLORIDE)
LIDOPEN
LQZ
LS-805
Lanabiotic
 
Laryng-o-jet
Leostesin
Lida-Mantle
Lidall
Lidocaina
Lidocaina [INN-Spanish]
Lidocaine
Lidocaine (JP15/USP/INN)
Lidocaine (VAN)
Lidocaine 4% Cream
Lidocaine Carbonate
Lidocaine Hydrocarbonate
Lidocaine Hydrochloride
Lidocaine Monohydrochloride
Lidocaine [USAN:INN:JAN]
Lidocaine hydrochloride
Lidocainum
Lidocainum [INN-Latin]
Lidocare Mist
Lidocaton
Lidocream 4
Lidocream 5
Lidoderm
Lidoderm 5
Lidoject-1
Lidoject-2
Lifestyles Epic Male Genital Desensitizer
Lignocaine
Lignocainum
Lingocaine
Lmx4
Lmx5
Lopac-L-5647
Lopac0_000669
MLS000069724
MLS000758263
MLS001074177
Maricaine
Maybridge1_002571
MolPort-001-783-478
N-(2,6-dimethylphenyl)-N(2),N(2)-diethylglycinamide
N-(2,6-dimethylphenyl)-N~2~,N~2~-diethylglycinamide
NCGC00015611-01
NCGC00015611-02
NCGC00015611-03
NCGC00015611-04
NCGC00015611-14
NCGC00022176-05
NCGC00022176-06
NCGC00022176-07
NCGC00022176-08
NCGC00022176-09
NINDS_000174
NSC 40030
NSC40030
Norwood Sunburn Spray
Numb Master Topical Anesthetic
Numb Nuts
Ocean Potion Instant Burn Relief Ice
Octocaine
Octocaine-100
Octocaine-50
Plum Smooth Plumb Numb Gelee
Premjact Male Desensitizer Pound International
Prestwick0_000050
Prestwick1_000050
Prestwick2_000050
Prestwick3_000050
Recticare
Remicaine
Rocephin Kit
Rucaina
S1357_Selleck
SAM001247018
SMR000058189
SPBio_001525
SPBio_002100
STK552033
Simplicity Desensitizing
Simply Numb Endure
Solarcaine
Solarcaine aloe extra burn relief cream
Solcain
Sole Serum
Spectrum2_001343
Spectrum3_001392
Spectrum4_000070
Spectrum5_001549
Spectrum_001118
UNII-98PI200987
WLN: 2N2 & 1VMR B1 F1
Walgreens Aloe Vera Pain Relieving
Xilina
Xilocaina
Xilocaina [Italian]
Xllina
Xycaine
Xylestesin
Xylesthesin
Xylocain
Xylocaine
Xylocaine (TN)
Xylocaine 5% Spinal
Xylocaine CO2
Xylocaine Dental Ointment
Xylocaine Endotracheal
Xylocaine Test Dose
Xylocaine Viscous
Xylocaine-Mpf
Xylocaine-Mpf with Glucose
Xylocaine-mpf
Xylocard
Xylocitin
Xyloneural (free base)
Xylotox
Zcaine Fast Acting Anesthetic
Zilactin-L
Zingo
alfa-Dietilamino-2,6-dimetilacetanilide
alfa-Dietilamino-2,6-dimetilacetanilide [Italian]
alpha-Diethylamino-2,6-dimethylacetanilide
alpha-diethylamino-2,6-dimethylacetanilide
lidocaine
nchembio.65-comp16
α-diethylamino-2,6-dimethylacetanilide
13
Lumefantrineapproved13382186-77-46437380
Synonyms:
(+-)-2,7-Dichloro-9-((Z)-P-chlorobenzylidene)-alpha-((dibutylamino)methyl)fluorene-4-methanol
(+-)-2,7-Dichloro-9-((Z)-p-chlorobenzylidene)-alpha((dibutylamino)methyl)fluorene-4-methanol
(+-)-2,7-Dichloro-9-((Z)-p-chlorobenzylidene)-alpha-((dibutylamino)methyl)fluorene-4-methanol
120583-69-9
2-(dibutylamino)-1-[(9Z)-2,7-dichloro-9-(4-chlorobenzylidene)-9H-fluoren-4-yl]ethanol
2-(dibutylamino)-1-[(9Z)-2,7-dichloro-9-[(4-chlorophenyl)methylidene]fluoren-4-yl]ethanol
2-Dibutylamino-1-[2,7-dichloro-9-(4-chloro-benzylidene)-9H-fluoren-4-yl]-ethanol
2-Dibutylamino-1-{2,7-dichloro-9-[1-(4-chloro-phenyl)-meth-(Z)-ylidene]-9H-fluoren-4-yl}-ethanol
82186-77-4
AC-4542
AC1O5NKD
Benflumetol
Bio-0132
C30H32Cl3NO
CHEBI:156095
 
CHEMBL38827
CID6437380
Coartem
D03821
DB06708
DL-Benflumelol
HSDB 7210
I14-7746
LS-177674
Lumefantrine
Lumefantrine (INN)
Lumefantrine [INN:BAN]
MolPort-006-394-826
NCGC00167490-01
UNII-F38R0JR742
dl-Benflumelol
14
Artemetherapproved13171963-77-4119380, 68911
Synonyms:
( )-alpha-Artemether
(1R,4S,5R,8S,9R,10S,12R,13R)-10-Methoxy-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.0^{4,13}.0^{8,13}]hexadecane
(3R,5aS,6R,8aS,9R,10S,12R,12aR)-10-methoxy-3,6,9-trimethyldecahydro-3,12-epoxypyrano[4,3-j][1,2]benzodioxepine
(3R,5aS,6R,8aS,9R,10S,12R,12aR)-Decahydro-10-methoxy-3,6,9-trimethyl-3,12-epoxy-12H-pyrano(4,3-j)-1,2-benzodioxepin
(3alpha,5abeta,6beta,8abeta,9alpha,10beta,12beta,12aR*)-isomer of artemether
(3r,5as,6r,8as,9r,10r,12r,12ar)-10-methoxy-3,6,9-trimethyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromene
(5aS,6R,8aS,9R,10S,12R,12aR)-10-methoxy-3,6,9-trimethyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromene
.beta.-Artemether
.beta.-Dihydroartemisinin methyl ether
.beta.-Methylether of 11-epi-dihydroartemisinin
10-Methoxy-1,5,9-trimethyl-(1R,4S,5R,8S,9R,10S,12R,13R)-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecane
10-methoxy-1,5,9-trimethyl-(1R,4S,5R,8S,9R,10S,12R,13R)-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecane
159573-83-8
3,12-Epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin, decahydro-10-methoxy-3,6,9-tri
71939-51-0
71963-77-4
74784-06-8
80286-56-2
93787-85-0
AC1L2APD
AC1L2XO8
AC1L9SH2
AC1L9UV0
AC1MI2ZX
AC1Q6Z74
AC1Q6Z7V
AR-1A4424
Arteannuin ether
Artemetero
Artemetero [INN-Spanish]
Artemether
Artemether (INN)
Artemether [INN]
Artemetheri
Artemetherum
Artemetherum [INN-Latin]
Artemisininelactol methyl ether
Artemos
Artenam
Artesaph
Artesian
Artimist
Artmether
BRN 5948416
C16H26O5
CHEBI:195280
 
CHEMBL411864
CHEMBL512315
CID10266705
CID104888
CID3062122
CID456408
CID500199
CID6483308
CID6712286
CID68911
CID9796294
CID9796295
CPD000469218
D02483
DB06697
Dihydroartemisinin methyl ether
Dihydroqinghaosu methyl ether
Dihydroquinghaosu methyl ether
Falcidol
Gvither
HMS2052L09
HSDB 7456
I06-0205
KST-1A8041
LS-176935
LS-64237
MLS001424249
Malartem
Methyl-dihydroartemisinine
NCI60_022891
NSC 665970
NSC665970
O-Methyldihydroartemisinine
Paluther
S2264_Selleck
SAM001246799
SM 224
SM 229
SM-224
SMR000469218
UNII-C7D6T3H22J
alpha-Artemether
alpha-Dihydroartemisinin methyl ether
artemether, (3R-(3alpha,5abeta,6beta,8abeta,9alpha,10alpha,12beta,12aR*))-isomer
artemether[inn]
beta-Artemether
beta-Dihydroartemisinin methyl ether
rither
15
Miconazoleapproved, investigational291222916-47-84189
Synonyms:
(+-)-1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl) imidazole
1-[2,4-Dichloro- beta-([2,4-dichloro- benzyl]oxy)phenethyl]imidazole
1-[2-(2,4-Dichloro-benzyloxy)-2-(2,4-dichloro-phenyl)-ethyl]-1H-imidazole
1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole
1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole
1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]imidazole
1-[2-(2,4-dichlorophenyl)-2-{[(2,4-dichlorophenyl)methyl]oxy}ethyl]-1H-imidazole
1-{2-[(2,4-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole
22832-87-7 (NITRATE)
22916-47-8
75319-47-0
AB00053500
AC1L1HM1
AKOS001574474
Aflorix(nitrate)
Albistat(nitrate)
Andergin(nitrate)
BPBio1_000279
BRD-A82396632-001-03-0
BRD-A82396632-008-02-7
BRN 0965511
BSPBio_000253
BSPBio_002033
CCRIS 7924
CHEBI:6923
CHEMBL91
CID4189
CPD-4501
Conofite(nitrate)
D00416
DB01110
Dactarin
Daktarin IV
Daktarin iv
Desenex
DivK1c_000156
EINECS 245-324-5
Epi-Monistat(nitrate)
Femizol-M
Florid(nitrate)
Gyno-Daktar(nitrate)
HMS1568M15
HMS2090B21
I14-14342
IDI1_000156
Imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl)methoxy)ethyl)- (9CI)
KBio1_000156
KBio2_001445
KBio2_004013
KBio2_006581
KBio3_001533
KBioGR_000581
KBioSS_001445
LS-78378
Lotrimin AF(nitrate)
MCZ
MJR 1762
MLS002222203
Makesense
Micantin (nitrate)
Micatin
 
Miconasil Nitrate
Miconazol
Miconazol [INN-Spanish]
Miconazole
Miconazole (JP15/USP/INN)
Miconazole 3
Miconazole 3 Combination Pack
Miconazole 7 Combination Pack
Miconazole [USAN:BAN:INN:JAN]
Miconazole nitrate salt
Miconazole-7
Miconazolo
Miconazolo [DCIT]
Miconazolum
Miconazolum [INN-Latin]
Micozole
Minostate
MolPort-002-557-553
Monazole 7
Monista (nitrate)
Monistat
Monistat (TN)
Monistat 1 Combination Pack
Monistat 3 Dual-Pak
Monistat 3 Vaginal Ovules
Monistat 5 Tampon
Monistat 7 Dual-Pak
Monistat 7 Vaginal Suppositories
Monistat Dual- PAK
Monistat IV
Monistat iv (TN)
Monistat iv (tn)
Monistat-Derm
NCI60_001353
NCI60_001380
NINDS_000156
NSC 170986
NSC169434
NSC170986
Novo-Miconazole Vaginal Ovules
Oprea1_091955
Oravig
Prestwick0_000067
Prestwick1_000067
Prestwick2_000067
Prestwick3_000067
Prestwick_335
R 18134
R-14,889
Rash Relief Antifungal
SMR001307249
SPBio_000976
SPBio_002174
STK834405
STOCK1S-93556
Spectrum2_001048
Spectrum3_000507
Spectrum4_000061
Spectrum5_001297
Spectrum_000965
UNII-7NNO0D7S5M
Vusion
Zimycan
imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl) methoxy)ethyl)- (9CI)
miconazole
16Epinephryl borate768
17Racepinephrine768
18Mydriatics470
19Artemisinins190
20Artemisinine190
21Artemether-lumefantrine combination126
22Anthelmintics363

Interventional clinical trials:

(show all 17)
idNameStatusNCT IDPhase
1Evaluation of Ureteral Patency in the Post-indigo Carmine EraRecruitingNCT02677623Phase 4
2Inhaled Nitric Oxide Study for Respiratory Failure in NewbornsTerminatedNCT00005776Phase 3
3Early Inhaled Nitric Oxide for Respiratory Failure in NewbornsTerminatedNCT00005773Phase 3
4Nitrite Mediated Cardioprotection During Coronary Artery Bypass SurgeryRecruitingNCT01098409Phase 2
5Sodium Nitrite in Lung Transplant Patients to Minimize the Risk of Pulmonary Graft DysfunctionRecruitingNCT01715883Phase 2
6Pharmacokinetics and Distribution of Dapsone in Leucocytes After Single-dose and Multiple-dose AdministrationCompletedNCT02493283Phase 1
7Safety, Tolerability, and Pharmacokinetic Study of Methylene Blue Following a 1 mg/kg Intravenous Dose in Healthy AdultsCompletedNCT02478281Phase 1
8Nitrite Infusion in Healthy VolunteersCompletedNCT00103025Phase 1
9Escalating Multiple-Dose Safety and Tolerance of WR 6026 Hydrochloride in HIV-Infected SubjectsCompletedNCT00000740Phase 1
10Pharmacokinetic and in Vitro Transmission Blocking Activities Study of Primaquine Compare to Methylene Blue in Healthy Volunteer Both G6PD Normal and G6PD DeficiencyCompletedNCT01668433Phase 1
11Methemoglobinemia in Patients With Childhood Hematologic Cancer or Aplastic Anemia Treated With DapsoneActive, not recruitingNCT00960050Phase 1
12Methemoglobinemia in Young Patients With Hematologic Cancer or Aplastic Anemia Treated With DapsoneCompletedNCT00993694
13Methemoglobinemia After Liposuction - Diagnostic by Pulse Oximetry and Blood Gas Analysis.CompletedNCT01766999
14Methemoglobin Levels in Generally Anesthetized Pediatric Dental Patients Receiving Local AnestheticsCompletedNCT01402869
15Study of Methemoglobin as a Biomarker of Tissue Hypoxia During Acute Hemodilution in Heart Surgery PatientsRecruitingNCT01883713
16Relapses in Plasmodium Ovale and Efficacy of Artemether-lumefantrine for Mixed Species and Non-falciparum MalariaRecruitingNCT02528279
17Safety and Efficacy of Primaquine for P. VivaxNot yet recruitingNCT01837992

Search NIH Clinical Center for Methemoglobinemia

Inferred drug relations via UMLS65/NDF-RT43:


Cochrane evidence based reviews: Methemoglobinemia

Genetic Tests for Methemoglobinemia

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Anatomical Context for Methemoglobinemia

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MalaCards organs/tissues related to Methemoglobinemia:

33
Kidney, Lung, Heart, Skin, Liver, Spleen, Brain

Animal Models for Methemoglobinemia or affiliated genes

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MGI Mouse Phenotypes related to Methemoglobinemia:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053708.0CYB5A, CYP2E1, HBB, HP, SOD1
2MP:00053857.3CYP2E1, G6PD, GSR, HBB, HP, SOD1

Publications for Methemoglobinemia

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Articles related to Methemoglobinemia:

(show top 50)    (show all 620)
idTitleAuthorsYear
1
Mycoplasma pneumoniae Pneumonia Associated With Methemoglobinemia and Anemia: An Overlooked Association? (26034771)
2015
2
Methemoglobinemia as a complication of topical dapsone. (25629755)
2015
3
Methemoglobinemia induced by lidocaine-prilocaine cream. (24834764)
2014
4
Acute methemoglobinemia caused by suicidal ingestion of liquid fertilizer. (25089725)
2014
5
A rare case of acquired methemoglobinemia associated with alkaptonuria. (25130113)
2014
6
Population frequency and age of c.806C > T mutation in CYB5R3 gene as cause of recessive congenital methemoglobinemia in Yakutia]. (23866629)
2013
7
Cetacaine induced methemoglobinemia: overview of analysis and treatment strategies. (23798277)
2013
8
Prilocaine- and lidocaine-induced methemoglobinemia is caused by human carboxylesterase-, CYP2E1-, and CYP3A4-mediated metabolic activation. (23530020)
2013
9
Methemoglobinemia and hemolytic anemia after rasburicase administration in a child with leukemia. (21057874)
2013
10
Methemoglobinemia after a mediastinal stab wound. (23896056)
2013
11
Acute Favism: Methemoglobinemia May Cause Cyanosis and Low Pulse Oximetry Readings. (23697341)
2013
12
Thinking outside of the blue box: a case presentation of neonatal methemoglobinemia. (24169929)
2013
13
Case files of the medical toxicology fellowship at Banner Good Samaritan Medical Center in Phoenix, AZ: methemoglobinemia following dapsone exposure. (21487934)
2011
14
Severe methemoglobinemia after dental anesthesia: a warning about propitocaine-induced methemoglobinemia in neonates. (20706742)
2010
15
Prilocain-induced methemoglobinemia after endovenous laser ablation. (20346699)
2010
16
Acute methemoglobinemia associated with ochronotic valvular heart disease: report of a case. (20333576)
2010
17
A 3-year-old boy with fever and oral lesions. Diagnosis: methemoglobinemia. (19968205)
2009
18
Severe hemolysis and methemoglobinemia following fava beans ingestion in glucose-6-phosphatase dehydrogenase deficiency: case report and literature review. (19263080)
2009
19
Lethal methemoglobinemia and automobile exhaust inhalation. (19261402)
2009
20
A novel L218P mutation in NADH-cytochrome b5 reductase associated with type I recessive congenital methemoglobinemia. (19579085)
2009
21
Recessive hereditary methemoglobinemia: two novel mutations in the NADH-cytochrome b5 reductase gene. (18343696)
2008
22
A novel G143D mutation in the NADH-cytochrome b5 reductase gene in an Indian patient with type I recessive hereditary methemoglobinemia. (17964195)
2008
23
Methemoglobinemia and benzocaine. (18049203)
2007
24
Methemoglobinemia: an industrial outbreak among rubber molding workers. (16688009)
2006
25
Images in cardiovascular medicine. Methemoglobinemia as a rare complication during a transesophageal echocardiogram. (16717156)
2006
26
Methemoglobinemia: life-threatening hazard of multiple drug ingestions. (19606800)
2006
27
Infant methemoglobinemia: the role of dietary nitrate in food and water. (16140723)
2005
28
A novel mutation in the DIA1 gene in a patient with methemoglobinemia type II. (15744830)
2005
29
Methylene blue in congenital methemoglobinemia: prophylactic or on demand? (16189344)
2005
30
Benzocaine-induced methemoglobinemia: a condition of which all endoscopists should be aware. (15497003)
2004
31
Methemoglobinemia from hydrogen peroxide in a patient with acatalasemia. (15220799)
2004
32
Cytochrome b5 reductase: the roles of the recessive congenital methemoglobinemia mutants P144L, L148P, and R159*. (15488472)
2004
33
A search for mutations in the DIA1 gene in case of hereditary methemoglobinemia type I in the iakut population]. (12884529)
2003
34
Heterologous expression of enzymopenic methemoglobinemia variants using a novel NADH:cytochrome c reductase fusion protein. (12821320)
2003
35
Severe methemoglobinemia after transesophageal echocardiography. (12756430)
2003
36
Use of methylene blue to treat methemoglobinemia in infancy. (12144224)
2001
37
Public notification to families with newborns at risk of methemoglobinemia from drinking water exposure, Clymer, New York, 1996-1998. (10537817)
1999
38
Methemoglobinemia after axillary block with bupivacaine and additional injection of lidocaine in the operative field. (10225085)
1999
39
Methemoglobinemia induced by accidental ingestion of nitrite. (17341917)
1998
40
Determination of concentration of cytosolic NADH-cytochrome b5 reductase in erythrocytes from normal Chinese adults, neonates and patients with hereditary methemoglobinemia by double-antibody sandwich ELISA. (9691146)
1998
41
Infant Methemoglobinemia in the Transylvania Region of Romania. (9891097)
1997
42
Index of suspicion. Case 2. Methemoglobinemia. (9360435)
1997
43
Correction of alimentary methemoglobinemia in children of preschool age by inclusion in the diet of products rich in antioxidants, vitamins and dietary fiber]. (8967053)
1996
44
Methemoglobinemia: a complication after fiberoptic orotracheal intubation with benzocaine spray. A case report. (7782367)
1995
45
Chronic methemoglobinemia: improving hemoglobin saturation monitoring during anesthesia. (7931458)
1994
46
A splicing mutation in the cytochrome b5 gene from a patient with congenital methemoglobinemia and pseudohermaphrodism. (8168836)
1994
47
Methemoglobinemia from topically applied anesthetic spray. (8065193)
1994
48
Topical anesthetic-induced methemoglobinemia in sheep: a comparison of benzocaine and lidocaine. (1601230)
1992
49
An enzyme variation in a case of congenital methemoglobinemia. (4354625)
1973
50
Studies on the congenital methemoglobinemia in Okinawa Islands. 3. Mass survey on Henza and Miyagi Islands. (4751402)
1973

Variations for Methemoglobinemia

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Expression for genes affiliated with Methemoglobinemia

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Search GEO for disease gene expression data for Methemoglobinemia.

Pathways for genes affiliated with Methemoglobinemia

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Pathways related to Methemoglobinemia according to GeneCards Suite gene sharing:

(show all 12)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.5HBB, SOD1
2
Show member pathways
9.5CYP2E1, CYP3A4
39.5CYP2E1, CYP3A4
49.5CYP2E1, CYP3A4
59.5CYP2E1, CYP3A4
69.5CYB5A, CYB5R3, G6PD
79.3G6PD, GSR
8
Show member pathways
9.1GSR, SOD1
99.1GSR, SOD1
10
Show member pathways
8.9CYB5A, CYB5R3, CYP2E1, CYP3A4
11
Show member pathways
8.7GSR, HBB, SOD1
12
Show member pathways
7.3CYB5A, CYB5R3, CYP2E1, CYP3A4, G6PD, GSR

GO Terms for genes affiliated with Methemoglobinemia

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Cellular components related to Methemoglobinemia according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1haptoglobin-hemoglobin complexGO:003183810.2HBB, HP
2endocytic vesicle lumenGO:007168210.1HBB, HP
3hemoglobin complexGO:000583310.1CYB5R3, HBB, HBG2
4blood microparticleGO:00725629.7HBB, HBG2, HP
5endoplasmic reticulum membraneGO:00057898.9CYB5A, CYB5R3, CYP2E1, CYP3A4
6intracellular membrane-bounded organelleGO:00432318.8CYB5A, CYP2E1, CYP3A4, G6PD
7mitochondrionGO:00057397.8CYB5A, CYB5R3, CYP2E1, GSR, SOD1
8extracellular exosomeGO:00700627.1CYB5A, CYB5R3, G6PD, GSR, HBB, HP

Biological processes related to Methemoglobinemia according to GeneCards Suite gene sharing:

(show all 15)
idNameGO IDScoreTop Affiliating Genes
1oxygen transportGO:001567110.4HBB, HBG2
2L-ascorbic acid metabolic processGO:001985210.4CYB5A, CYB5R3
3cholesterol biosynthetic processGO:000669510.2CYB5R3, G6PD
4monoterpenoid metabolic processGO:001609810.0CYP2E1, CYP3A4
5heterocycle metabolic processGO:004648310.0CYP2E1, CYP3A4
6drug metabolic processGO:001714410.0CYP2E1, CYP3A4
7cellular response to oxidative stressGO:003459910.0G6PD, SOD1
8exogenous drug catabolic processGO:00427389.9CYP2E1, CYP3A4
9response to reactive oxygen speciesGO:00003029.7GSR, SOD1
10positive regulation of cell deathGO:00109429.5HBB, HP
11response to hydrogen peroxideGO:00425429.5HBB, HP, SOD1
12glutathione metabolic processGO:00067499.3G6PD, GSR, SOD1
13response to ethanolGO:00454719.1CYP2E1, G6PD, SOD1
14small molecule metabolic processGO:00442817.2CYB5A, CYB5R3, CYP2E1, CYP3A4, G6PD, GSR
15oxidation-reduction processGO:00551146.7CYB5A, CYB5R3, CYP2E1, CYP3A4, G6PD, GSR

Molecular functions related to Methemoglobinemia according to GeneCards Suite gene sharing:

(show all 11)
idNameGO IDScoreTop Affiliating Genes
1oxygen transporter activityGO:000534410.3HBB, HBG2
2hemoglobin bindingGO:003049210.0HBB, HP
3steroid hydroxylase activityGO:00083959.9CYP2E1, CYP3A4
4oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygenGO:00167129.9CYP2E1, CYP3A4
5monooxygenase activityGO:00044979.9CYP2E1, CYP3A4
6NADP bindingGO:00506619.3G6PD, GSR
7iron ion bindingGO:00055069.1CYP2E1, CYP3A4, HBB, HBG2
8oxygen bindingGO:00198259.1CYP2E1, CYP3A4, HBB, HBG2
9oxidoreductase activityGO:00164918.4CYB5R3, CYP2E1, CYP3A4, GSR
10enzyme bindingGO:00198998.4CYB5A, CYP2E1, CYP3A4, SOD1
11heme bindingGO:00200378.3CYB5A, CYP2E1, CYP3A4, HBB, HBG2

Sources for Methemoglobinemia

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet