MPA
MCID: MCR088
MIFTS: 58

Microscopic Polyangiitis (MPA) malady

Neuronal, Nephrological, Respiratory, Bone, Cardiovascular categories

Summaries for Microscopic Polyangiitis

Sources:
43NIH Rare Diseases, 64Wikipedia, 33MalaCards
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NIH Rare Diseases:43 Microscopic polyangiitis (mpa) is a disorder that causes blood vessel inflammation (vasculitis), which can lead to organ damage. the kidneys, lungs, nerves, skin, and joints are the most commonly affected areas of the body. mpa is diagnosed in people of all ages, all ethnicities, and both genders. the cause of this disorder is unknown. last updated: 2/4/2009

MalaCards: Microscopic Polyangiitis, also known as microscopic polyarteritis, is related to wegener's granulomatosis and churg-strauss syndrome, and has symptoms including cutaneous rash, erythema/erythematous lesions/erythroderma/polymorphous erythema and hemoptysis. An important gene associated with Microscopic Polyangiitis is KIR2DS3 (killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 3), and among its related pathways are Rheumatoid arthritis and Allograft rejection. The compounds valine and glutamate have been mentioned in the context of this disorder. Affiliated tissues include bone marrow, spinal cord and small intestine, and related mouse phenotypes are cardiovascular system and homeostasis/metabolism.

Wikipedia:64 Microscopic polyangiitis (also known as \"Microscopic polyarteritis,\" \"Microscopic polyarteritis... more...

Aliases & Classifications for Microscopic Polyangiitis

Sources:
43NIH Rare Diseases, 49Orphanet, 61UMLS, 36MESH via Orphanet, 26ICD10 via Orphanet, 62UMLS via Orphanet, 25ICD10
See all sources

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Neuronal, Nephrological, Respiratory, Bone, Cardiovascular


Characteristics (Orphanet epidemiological data):

49
microscopic polyangiitis:
Inheritance: Sporadic; Prevalence: 1-9/100000; Age of onset: Adulthood; Age of death: Adult


Aliases & Descriptions:

microscopic polyangiitis 43 49 61
microscopic polyarteritis 49 61
vasculitis, leukocytoclastic, cutaneous 61
hypersensitivity angiitis 49
micropolyangiitis 49
mpa 49


External Ids:

MESH via Orphanet36 D055953
ICD10 via Orphanet26 M31.7
UMLS via Orphanet62 C0343192
ICD1025 M31.0, M31.7

Related Diseases for Microscopic Polyangiitis

Sources:
17GeneCards, 18GeneDecks
See all sources

Diseases related to Microscopic Polyangiitis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 198)
idRelated DiseaseScoreTop Affiliating Genes
1wegener's granulomatosis31.1CTLA4, MPO, PRTN3, SELE
2churg-strauss syndrome31.1PRTN3, MPO
3vasculitis31.1SELE, FCGR3B, PRTN3, MPO, CTLA4, TNFRSF1B
4hepatitis c30.4GGT1, HLA-DRB1, CTLA4, TNFRSF1B
5nephritis30.3FCGR3A, FCGR2A, FCGR3B, PRTN3, MPO
6primary biliary cirrhosis30.3GGT1, PRTN3, HLA-DRB1, CTLA4
7graft versus host disease30.3KIR3DL1, IL2RA, HLA-DRB1, CTLA4
8urticaria30.1SELE
9rheumatoid vasculitis30.1SELE
10antiphospholipid syndrome30.1SELE
11systemic lupus erythematosus30.1FCGR2A, FCGR3B
12rapidly progressive glomerulonephritis30.1MPO, PRTN3
13thyroiditis30.1HLA-DRB1, CTLA4
14lupus nephritis30.1TNFRSF1B, IL2RA, FCGR2A, FCGR3A
15autoimmune hepatitis30.1CTLA4, HLA-DQB1, HLA-DRB1, GGT1
16tuberculosis30.1TNFRSF1B, HLA-DQB1, HLA-DRB1, CX3CL1, IL2RA
17asthma30.1CTLA4, HLA-DRB1, MPO, PRTN3, IL2RA, FCGR3B
18arthritis30.0SELE, FCGR3A, FCGR2A, FCGR2B, FCGR3B, PRTN3
19micro syndrome10.8
20polyarteritis nodosa10.8
21n syndrome10.7
22diffuse alveolar hemorrhage10.3
23hepatitis d10.2
24amyloidosis10.2
25cutaneous sclerosis10.2
26bacteremia10.2
27allergic cutaneous vasculitis10.1
28cutaneous necrotizing vasculitis10.1
29crescentic glomerulonephritis10.1
30cardiac tamponade10.1
31hereditary hemorrhagic telangiectasia10.1
32relapsing polychondritis10.1
33pulmonary systemic sclerosis10.1
34autoimmune thyroiditis10.1
35idiopathic pulmonary fibrosis10.1
36sensorineural hearing loss10.1
37coronary aneurysm10.1
38henoch-schoenlein purpura10.1
39good syndrome10.1
40intracranial aneurysm10.1
41goodpasture syndrome10.1
42takayasu's arteritis10.1
43miliary tuberculosis10.1
44asbestosis10.1
45polymyalgia rheumatica10.1
46subacute bacterial endocarditis10.1
47temporal arteritis10.1
48hepatitis a10.1
49aortic aneurysm10.1
50aortic valve insufficiency10.1

Graphical network of the top 20 diseases related to Microscopic Polyangiitis:



Diseases related to microscopic polyangiitis

Clinical Features for Microscopic Polyangiitis

Sources:
49Orphanet
See all sources


Symptoms:

49 (show all 39)
  • cutaneous rash
  • erythema/erythematous lesions/erythroderma/polymorphous erythema
  • hemoptysis
  • lung/pulmonary/alveolar hemorrhage/hematoma
  • vascularitis/vasculitides/arteritis
  • renal glomerular defect/glomerulopathy
  • renal failure
  • hematuria/microhematuria
  • pollakiuria/polyuria/dysuria/anuria/acute urine retention/oliguria
  • neuritis/polyneuritis/multineuritis
  • autoimmunity/autoimmune reaction/autoantibodies
  • fever/chilling
  • biological inflammatory syndrome/increased erythrocyte sedimentation rate/crp
  • chronic skin infection/ulcerations/ulcers/cancrum
  • purpura/petichiae
  • nausea/vomiting/regurgitation/merycism/hyperemesis
  • acute abdominal pain/colic
  • acute diarrhea
  • gastrointestinal bleeding/hemorrhage/hematemesis/melena/rectorrhagia
  • intestinal perforation
  • peritonitis/peritoneal abscess
  • venous thrombosis/phlebitis/thrombophlebitis
  • mesenteric/intestinal infarction
  • myalgia/muscular pain
  • articular/joint pain/arthralgia
  • chronic uveitis/blepharitis/episcleritis/scleritis/conjonctivitis/keratitis
  • retinal vascular anomalies/retinal telangiectasia
  • nasal congestion/sinusitis/rhinitis/rhinorrhea
  • cutis marmorata/marbled skin/livedo
  • subcutaneous nodules/lipomas/tumefaction/swelling
  • pancreatitis
  • pericardium anomalies/pericarditis/absence/cysts/pericardial effusion
  • cardiac rhythm disorder/arrhythmia
  • heart/cardiac failure
  • gangrena/necrosis
  • peripheral neuropathy
  • paresthesia/dysesthesia/hypoesthesia/anesthesia/numbness
  • arthritis/synovitis/synovial proliferation
  • epistaxis/nose bleeding

Drugs & Therapeutics for Microscopic Polyangiitis

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
See all sources

Approved drugs:

Search CenterWatch for Microscopic Polyangiitis

Drug clinical trials:

Search ClinicalTrials for Microscopic Polyangiitis

Search NIH Clinical Center for Microscopic Polyangiitis

Search CenterWatch for Microscopic Polyangiitis

Genetic Tests for Microscopic Polyangiitis

Anatomical Context for Microscopic Polyangiitis

Sources:
33MalaCards
See all sources

MalaCards organs/tissues related to Microscopic Polyangiitis:

33
Bone marrow, Spinal cord, Small intestine, Colon, Kidney, Liver, Lung, Thyroid, Breast, Skin, Prostate, T cells, B cells, Endothelial

Animal Models for Microscopic Polyangiitis or affiliated genes

Sources:
37MGI, 28inGenious Targeting Laboratory
See all sources

Publications for Microscopic Polyangiitis

Sources:
51PubMed
See all sources

Articles related to Microscopic Polyangiitis:

(show top 50)    (show all 308)
idTitleAuthorsYear
1
Microscopic polyangiitis on A^a8,F-FDG PET/CT of a patient with fever of unknown origin presenting as isolated diffuse renal hypermetabolism. (23632959)
2013
2
Gastrointestinal involvement in granulomatosis with polyangiitis and microscopic polyangiitis: histological features and outcome. (24400862)
2013
3
Predicting mortality in microscopic polyangiitis with renal involvement: a survival analysis based on 64 patients. (23110307)
2013
4
The first Korean case of disseminated mycetoma caused by Nocardia pseudobrasiliensis in a patient on long-term corticosteroid therapy for the treatment of microscopic polyangiitis. (23667849)
2013
5
Recombinant activated factor VII for diffuse alveolar hemorrhage in microscopic polyangiitis. (22787316)
2012
6
Gradient echo T2*-weighted magnetic resonance imaging revealing cerebral microbleeds in a patient with microscopic polyangiitis complicated by cerebrovascular disease. (21640612)
2012
7
Genetics of microscopic polyangiitis in the Japanese population. (23555527)
2012
8
Expansions of CD4+CD28- and CD8+CD28- T cells in granulomatosis with polyangiitis and microscopic polyangiitis are associated with cytomegalovirus infection but not with disease activity. (22753656)
2012
9
Type 1 autoimmune hepatitis in a patient with microscopic polyangiitis: challenges in diagnosis and treatment. (21295790)
2011
10
Microscopic polyangiitis presenting with peripheral and central neurological manifestations. (21681367)
2011
11
Cyclophosphamide as induction therapy for Wegener's granulomatosis and microscopic polyangiitis. (21447129)
2011
12
Recovery of renal function in a dialysis-dependent patient with microscopic polyangiitis and both myeloperoxidase anti-neutrophil cytoplasmic antibodies and anti-glomerular basement membrane antibodies. (21804289)
2011
13
Estimation of BVAS in patients with microscopic polyangiitis in Japan. (21887487)
2011
14
Livedo reticularis and erythematous macules of the forearms indicating cutaneous microscopic polyangiitis. (21035582)
2010
15
Microscopic polyangiitis accompanied by septic vasculitis and Henoch-SchAPnlein purpura. (20876040)
2010
16
Interstitial lung disease as a presenting manifestation of microscopic polyangiitis successfully treated with mycophenolate mofetil. (19327249)
2009
17
Successful treatment of severe juvenile microscopic polyangiitis with rituximab. (19390907)
2009
18
MPO-ANCA- and IgA-positive systemic vasculitis: a possibly overlapping syndrome of microscopic polyangiitis and Henoch-Schoenlein purpura. (19586496)
2009
19
Ruptured arterial aneurysm of the kidney in a patient with microscopic polyangiitis. (18344639)
2008
20
Microscopic polyangiitis presenting as a "pulmonary-muscle" syndrome: is subclinical alveolar hemorrhage the mechanism of pulmonary fibrosis? (17530647)
2007
21
Prevalence of Wegener's granulomatosis, microscopic polyangiitis, polyarteritis nodosa and Churg-Strauss syndrome within a defined population in southern Sweden. (17553910)
2007
22
Microscopic polyangiitis or Wegener's granulomatosis? That is the question. (16548912)
2006
23
No evidence of parvovirus B19 in tissue samples from patients with polyarteritis nodosa and microscopic polyangiitis as assessed by the polymerase chain reaction. (16474040)
2006
24
Microscopic polyangiitis associated with thymoma, exacerbating after thymectomy. (17060003)
2006
25
Childhood microscopic polyangiitis associated with MPO-ANCA. (16252100)
2006
26
Ocular manifestations in patients with microscopic polyangiitis. (15751255)
2005
27
Asbestosis and probable microscopic polyangiitis. (15332139)
2004
28
Efficacy of granulocytapheresis and leukocytapheresis for the treatment of microscopic polyangiitis. (15154873)
2004
29
Neonatal microscopic polyangiitis secondary to transfer of maternal myeloperoxidase-antineutrophil cytoplasmic antibody resulting in neonatal pulmonary hemorrhage and renal involvement. (15521377)
2004
30
Microscopic polyangiitis associated with marked systemic bleeding tendency caused by disseminated intravascular coagulation. (14518675)
2003
31
Anti-myeloperoxidase antibodies in patients with microscopic polyangiitis. (14646155)
2003
32
Pulmonary interstitial fibrosis as a presenting manifestation in perinuclear antineutrophilic cytoplasmic antibody microscopic polyangiitis. (12527637)
2003
33
Vasculitis: Wegener granulomatosis, Churg-Strauss syndrome, microscopic polyangiitis, polyarteritis nodosa, and Takayasu arteritis. (12418444)
2002
34
Conventional treatment and outcome of Wegener's granulomatosis and microscopic polyangiitis. (12086249)
2002
35
Microscopic polyangiitis in a patient with relapsing polychondritis. (11257169)
2001
36
Antineutrophil cytoplasmic antibodies reacting with the pro form of proteinase 3 and disease activity in patients with Wegener's granulomatosis and microscopic polyangiitis. (11229478)
2001
37
Pachymeningitis in microscopic polyangiitis (MPA): a case report and a review of central nervous system involvement in MPA. (10895382)
2000
38
Microscopic polyangiitis]. (10896971)
2000
39
Mycophenolate mofetil for maintenance therapy of Wegener's granulomatosis and microscopic polyangiitis: a pilot study in 11 patients with renal involvement. (10477149)
1999
40
Hypersensitivity vasculitis (microscopic polyangiitis) in pregnancy with transmission to the neonate. (9746391)
1998
41
Clinical course and symptomatic prediagnostic period of patients with Wegener's granulomatosis and microscopic polyangiitis. (9606740)
1998
42
Treatment of polyarteritis nodosa and microscopic polyangiitis. (9870866)
1998
43
Demonstration of microaneurysms at the interlobular arteries of the kidneys in microscopic polyangiitis: a three-dimensional study. (9496823)
1998
44
von Willebrand factor antigen and adhesive molecules in Wegener's granulomatosis and microscopic polyangiitis. (9184277)
1997
45
Arteritis temporalis in a patient with microscopic polyangiitis. (9241622)
1997
46
Prognostic markers in patients with antineutrophil cytoplasmic autoantibody-associated microscopic polyangiitis and glomerulonephritis. (8808106)
1996
47
Polyarteritis nodosa, microscopic polyangiitis, and Churg-Strauss syndrome. Clinical aspects and treatment. (8592743)
1995
48
Polyarteritis nodosa and microscopic polyangiitis. (7606855)
1995
49
Antineutrophil cytoplasmic antibodies (ANCA) and abnormal angiograms in polyarteritis nodosa and Churg-Strauss syndrome: indications for the diagnosis of microscopic polyangiitis. (8734079)
1995
50
Distinguishing polyarteritis nodosa from microscopic polyangiitis and implications for treatment. (7718418)
1995

Genetic Variations for Microscopic Polyangiitis

Expression for genes affiliated with Microscopic Polyangiitis

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Microscopic Polyangiitis

Search GEO for disease gene expression data for Microscopic Polyangiitis.

Pathways for genes affiliated with Microscopic Polyangiitis

Sources:
30KEGG, 52QIAGEN, 54Reactome, 12EMD Millipore, 38NCBI BioSystems Database
See all sources

Pathways related to Microscopic Polyangiitis according to GeneCards/GeneDecks:

(show all 21)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
110.3CTLA4
2
Hide members
10.0KIR3DL1, KIR2DS3, KIR2DL1
39.9FCGR2B, FCGR2A, FCGR3A
4
Hide members
9.9FCGR2A, FCGR2B, FCGR3B
5
Hide members
9.7HLA-DRB1, HLA-DQB1, CTLA4
69.7SELE, CX3CL1, TNFRSF1B
79.7HLA-DQB1, HLA-DRB1, IL2RA
8
Hide members
9.6KIR2DL1, KIR3DL1, FCGR2B, FCGR2A, FCGR3A
9
Hide members
9.5HLA-DQB1, HLA-DRB1, IL2RA, FCGR2B
10
Hide members
9.5HLA-DQB1, HLA-DRB1, IL2RA, FCGR2B
119.5CTLA4, HLA-DQB1, HLA-DRB1, SELE
12
Hide members
9.5CTLA4, HLA-DQB1, HLA-DRB1, IL2RA
13
Hide members
9.5KIR2DL1, KIR2DS3, KIR3DL1, FCGR3B, FCGR2B, FCGR3A
14
Hide members
9.5KIR2DL1, KIR3DS1, KIR3DL1, FCGR2B, FCGR2A, FCGR3A
159.4LILRA2, FCGR3B, FCGR2B, FCGR2A, FCGR3A
16
Hide members
9.4HLA-DQB1, HLA-DRB1, FCGR3B, FCGR2A, FCGR3A
17
Hide members
9.4HLA-DQB1, HLA-DRB1, FCGR3B, FCGR2A, FCGR3A
18
Hide members
9.3IL2RA, HLA-DRB1, HLA-DQB1, CTLA4, TNFRSF1B
199.2HLA-DQB1, HLA-DRB1, FCGR3B, FCGR2B, FCGR2A, FCGR3A
209.2FCGR3A, FCGR2A, FCGR2B, FCGR3B, HLA-DRB1, HLA-DQB1
219.1HLA-DQB1, HLA-DRB1, MPO, FCGR3B, FCGR2B, FCGR2A

Compounds for genes affiliated with Microscopic Polyangiitis

Sources:
45Novoseek, 11DrugBank, 50PharmGKB, 24HMDB, 29IUPHAR, 2BitterDB, 60Tocris Bioscience
See all sources

Compounds related to Microscopic Polyangiitis according to GeneCards/GeneDecks:

(show top 50)    (show all 82)
idCompoundScoreTop Affiliating Genes
1valine4510.7MB
2glutamate4510.2CX3CL1, MB
3Palivizumab1110.2FCGR3A, FCGR2B, FCGR3B, FCGR2A
4Intravenous Immunoglobulin1110.2FCGR3A, FCGR2A, FCGR2B, FCGR3B
5Ibritumomab1110.2FCGR3B, FCGR2A, FCGR3A, FCGR2B
6bevacizumab50 1111.2FCGR2B, FCGR3B, FCGR3A, FCGR2A
7tositumomab50 1111.2FCGR2A, FCGR2B, FCGR3B, FCGR3A
8alefacept45 1111.2FCGR3A, FCGR2A, FCGR2B, FCGR3B
9Muromonab1110.2FCGR3B, FCGR2B, FCGR2A, FCGR3A
10efalizumab45 1111.1FCGR2A, FCGR3A, FCGR3B, FCGR2B
11gemtuzumab ozogamicin45 1111.1FCGR3B, FCGR2B, FCGR2A, FCGR3A
12adalimumab45 50 1112.1FCGR2A, FCGR3A, FCGR3B, FCGR2B
13abciximab45 1111.1FCGR2A, FCGR3B, FCGR2B, FCGR3A
14cetuximab45 50 1112.1FCGR3A, FCGR2B, FCGR2A, FCGR3B
15n-(2-mercaptopropionyl)glycine4510.1MPO, MB
16trastuzumab45 50 1112.1FCGR2A, FCGR2B, FCGR3B, FCGR3A
17gold sodium thiomalate4510.1SELE, IL2RA, HLA-DRB1
18fitc4510.1TNFRSF1B, FCGR2B, IL2RA
19nadph45 2411.0PRTN3, FCGR2A
20sulfasalazine45 29 50 1113.0SELE, IL2RA, MPO
21con a4510.0TNFRSF1B, CTLA4, IL2RA
22polyethylene glycol4510.0MB, TNFRSF1B, SELE, MPO
23etanercept45 50 1112.0FCGR3A, TNFRSF1B, FCGR3B, FCGR2B, FCGR2A
24daclizumab45 1111.0FCGR3B, FCGR3A, FCGR2A, FCGR2B, IL2RA
25basiliximab45 1110.9FCGR3A, FCGR2A, FCGR2B, FCGR3B, IL2RA
26natalizumab45 1110.9FCGR3B, FCGR3A, FCGR2A, IL2RA, FCGR2B
27alemtuzumab45 1110.9FCGR2A, FCGR3B, IL2RA, FCGR3A, FCGR2B
28infliximab45 50 1111.9TNFRSF1B, SELE, IL2RA, PRTN3
29ivig459.9IL2RA, TNFRSF1B, FCGR2B, FCGR2A, FCGR3A
30prednisolone45 29 1111.8MB, FCGR2A, FCGR3B, IL2RA, MPO
31clozapine45 29 50 1112.8TNFRSF1B, MPO, GGT1, IL2RA
32mycophenolate mofetil45 50 1111.8IL2RA, GGT1, CTLA4, SELE
33methimazole45 2 1111.8MPO, IL2RA, SELE
34heparin45 29 11 2412.7IL2RA, MB, MPO, FCGR2A, SELE
35histamine45 29 2411.7SELE, FCGR2A, FCGR2B, IL2RA, MPO
36formaldehyde45 2410.6PRTN3, IL2RA, SELE, MPO
37h2o2459.6TNFRSF1B, FCGR2A, MPO, MB, IL2RA, FCGR3B
38n acetylcysteine459.6MPO, MB, IL2RA, GGT1, SELE
39fmlp459.5PRTN3, FCGR3B, MPO, FCGR2B, TNFRSF1B, FCGR2A
40polysaccharide459.5SELE, GGT1, FCGR2A, FCGR3B, IL2RA
41acetylcholine45 50 29 11 2413.5GGT1, MPO, IL2RA, MB, CTLA4
42lysine459.5KIR3DL1, TNFRSF1B, CTLA4, HLA-DRB1, IL2RA, FCGR2A
43rituximab45 50 1111.5FCGR3A, PRTN3, IL2RA, FCGR3B, FCGR2B, FCGR2A
44cholesterol45 29 11 2412.2TNFRSF1B, CTLA4, FCGR2A, FCGR3A, GGT1, SELE
45methotrexate45 50 1111.2IL2RA, HLA-DRB1, CTLA4, TNFRSF1B, GGT1, SELE
46arginine459.2TNFRSF1B, MB, FCGR2A, FCGR3A, IL2RA, HLA-DRB1
47genistein45 29 60 2 11 2414.0FCGR2B, FCGR3B, IL2RA, PRTN3, SELE
48serine459.0SELE, PRTN3, FCGR2A, FCGR2B, MB, MPO
49lipid458.7PRTN3, KIR3DL1, KIR2DL1, FCGR2B, GGT1, CTLA4
50tyrosine458.4KIR3DL1, IL2RA, TNFRSF1B, CTLA4, HLA-DQB1, FCGR2A

GO Terms for genes affiliated with Microscopic Polyangiitis

Sources:
16Gene Ontology
See all sources

Cellular components related to Microscopic Polyangiitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1MHC class II protein complexGO:04261310.0HLA-DRB1, HLA-DQB1
2external side of plasma membraneGO:0098979.5CTLA4, HLA-DRB1, IL2RA, FCGR3A
3integral to plasma membraneGO:0058879.1CTLA4, HLA-DRB1, KIR2DL1, KIR2DS3, KIR3DS1, KIR3DL1
4plasma membraneGO:0058866.9SELE, TNFRSF1B, CTLA4, HLA-DQB1, HLA-DRB1, PRTN3

Biological processes related to Microscopic Polyangiitis according to GeneCards/GeneDecks:

(show all 7)
idNameGO IDScoreTop Affiliating Genes
1immunoglobulin production involved in immunoglobulin mediated immune responseGO:00238110.0HLA-DRB1, HLA-DQB1
2inflammatory response to antigenic stimulusGO:00243710.0IL2RA, HLA-DRB1
3regulation of immune responseGO:0507769.9KIR2DL1, KIR3DL1, FCGR2B, FCGR3A
4defense responseGO:0069529.7CX3CL1, LILRA2, MPO
5humoral immune response mediated by circulating immunoglobulinGO:0024559.7HLA-DRB1, HLA-DQB1
6T cell costimulationGO:0312959.6CTLA4, HLA-DQB1, HLA-DRB1
7immune responseGO:0069558.1FCGR3A, TNFRSF1B, CTLA4, HLA-DQB1, HLA-DRB1, CX3CL1

Molecular functions related to Microscopic Polyangiitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1MHC class II receptor activityGO:03239510.0HLA-DRB1, HLA-DQB1
2IgG bindingGO:0198649.4FCGR3A, FCGR2A, FCGR2B, FCGR3B

Products for genes affiliated with Microscopic Polyangiitis

  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Microscopic Polyangiitis

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet