MCID: MDD005
MIFTS: 27

Middle Lobe Syndrome malady

Category: Respiratory diseases

Aliases & Classifications for Middle Lobe Syndrome

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Aliases & Descriptions for Middle Lobe Syndrome:

Name: Middle Lobe Syndrome 10 12 36 65

Classifications:



External Ids:

Disease Ontology10 DOID:2810
SNOMED-CT59 28295001
MeSH36 D008878
UMLS65 C0026069

Summaries for Middle Lobe Syndrome

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Disease Ontology:10 A lung disease that is defined as a recurrent or chronic collapse of the right middle lobe, right upper lobe or lingula of the lung. It is caused by endobronchial tumour, granulomatous infections, lymphadenopathy, foreign bodies, endobronchial silicotic nodules, inspissated mucus associated with cystic fibrosis or inflammation as a result of an infection.

MalaCards based summary: Middle Lobe Syndrome is related to retinitis and thyroiditis. An important gene associated with Middle Lobe Syndrome is FLNC (Filamin C), and among its related pathways is Proteoglycans in cancer. Affiliated tissues include lung, brain and liver.

Related Diseases for Middle Lobe Syndrome

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Graphical network of the top 20 diseases related to Middle Lobe Syndrome:



Diseases related to middle lobe syndrome

Symptoms for Middle Lobe Syndrome

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Drugs & Therapeutics for Middle Lobe Syndrome

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Drugs for Middle Lobe Syndrome (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Epinephrineapproved83451-43-45816
Synonyms:
(-)-(R)-Epinephrine
(-)-3,4-Dihydroxy-a-[2-(methylamino)ethyl]benzyl alcohol
(-)-3,4-Dihydroxy-alpha-((methylamino)methyl)benzyl alcohol
(-)-3,4-Dihydroxy-alpha-[2-(methylamino)ethyl]benzyl alcohol
(-)-3,4-dihydroxy-a-[(methylamino)methyl]-Benzyl alcohol
(-)-3,4-dihydroxy-alpha-[(methylamino)methyl]-Benzyl alcohol
(-)-Adrenalin
(-)-Adrenaline
(-)-Epinephrine
(-)-R-Epinephrine
(R)-(-)-Adnephrine
(R)-(-)-Adrenaline
(R)-(-)-Epinephrine
(R)-(-)-Epirenamine
(R)-(−)-adrenaline
(R)-4-[1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol
(R)-4-[1-hydroxy-2-(methylamino)ethyl]-1,2-Benzenediol
(R)-Adrenaline
(R)-Epinephrine
(−)-adrenaline
02252_FLUKA
1-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol
1-Adrenalin
1-Epinephrine
4-(1-Hydroxy-2-(methylamino)ethyl)-1,2-benzenediol
4-(1-hydroxy-2-methylamino-ethyl)benzene-1,2-diol
4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-1,2-Benzenediol
4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol
4-[(1R)-1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol
51-43-4
51-43-4 (FREE BASE)
51028-73-0
A0173
AC-13188
AC1L1L7B
ADR ADRENALINE
ADROP
AI3-19015
Adnephrine
Adrenaclick
Adrenal
Adrenalin
Adrenalin (TN)
Adrenalin in Oil
Adrenalin-Medihaler
Adrenalina
Adrenalina [DCIT]
Adrenaline
Adrenaline (JP15)
Adrenaline/Epinephrine
Adrenalinum
Adrenamine
Adrenan
Adrenapax
Adrenasol
Adrenatrate
Adrenine
Adrenodis
Adrenohorma
Adrenosan
Adrenutol
Adrin
Adrine
Ana-Guard
Ana-Kit
Antiasthmatique
Asmatane Mist
Asthma meter mist
Asthma-nefrin
Asthmahaler Mist
Asthmanefrin
Astmahalin
Astminhal
Auvi-q
BIDD:GT0119
Balmadren
Bernarenin
Biorenine
Bosmin
Brevirenin
Bronkaid
Bronkaid Mist
Bronkaid Suspension Mist
Bupivacaine Hcl and Epinephrine
C00788
CCRIS 4812
CHEBI:28918
CHEMBL679
CID5816
Chelafrin
Citanest Forte
Corisol
D-Epifrin
D-Epinephrine
D00095
DB00668
Drenamist
Dylephrin
Dyspne-Inhal
E4250_SIGMA
EINECS 200-098-7
EPI E Z PEN JR
EPIPEN E Z PEN
EPIPEN JR
Epi EZ Pen Jr
Epifrin
Epiglaufrin
Epinefrin
Epinefrin [Czech]
Epinefrina
Epinefrina [INN-Spanish]
Epinephran
Epinephrin
Epinephrine
Epinephrine (USP)
Epinephrine (USP/INN)
Epinephrine [USAN:INN:JAN]
Epinephrine bitartrate
Epinephrine chloride
Epinephrine hydrochloride
Epinephrinum
Epinephrinum [INN-Latin]
Epipen
Epipen (TN)
Epipen Auto-Injector
Epipen EZ Pen
Epipen Jr
Epipen Jr.
Epipen Jr. Auto-Injector
Epipen jr
Epirenamine
Epirenan
Epirenin
Epitrate
Eppy
 
Esphygmogenina
Exadrin
Glaucon
Glaucosan
Glauposine
Glycirenan
HSCI1_000215
HSDB 4289
Haemostasin
Haemostatin
Hektalin
Hemisine
Hemostasin
Hemostatin
Hypernephrin
Hyporenin
IOP
Intranefrin
Iontocaine
Isoptoepinal
Kidoline
L-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol
L-Adrenaline
L-Adrenaline Base
L-Epinehphrine
L-Epinephrine
L-Epirenamine
L-Methylaminoethanolcatechol
L-epinephrine
LS-156
Levo-Methylaminoethanolcatechol
Levoadrenaline
Levoepinephrine
Levorenen
Levorenin
Levorenine
Levoreninum
Lopac-E-4642
Lyodrin
Lyophrin
Medihaler-Epi
Metanephrin
Methylaminoethanolcatechol
Methylarterenol
Micronefrin
Micronephrine
MolPort-002-051-368
Mucidrina
Myosthenine
Mytrate
NCGC00015417-01
NCGC00142615-01
NCGC00142615-03
NCGC00142615-04
NCGC00142615-05
NCGC00142615-06
NCGC00142615-07
NSC 62786
NSC62786
Nephridine
Nieraline
PDSP1_001120
PDSP2_001104
Paranephrin
Primatene
Primatene Mist
Primatene Mist Refill
Prime Asthma Relief
R-(-)-Epinephrine
R-Adrenaline
RCRA waste no. P042
Racemic Epinephrine
Racepinephrine
Rcra waste number P042
Renagladin
Renaglandin
Renaglandulin
Renaleptine
Renalina
Renoform
Renostypricin
Renostypticin
Renostyptin
SMP1_000227
ST069368
SUS-PHRINE SULFITE-FREE
Scurenaline
Septocaine
Simplene
Sindrenina
Soladren
Sphygmogenin
Stryptirenal
Styptirenal
Supracapsulin
Supradin
Supranefran
Supranephrane
Supranephrine
Supranol
Suprarenaline
Suprarenin
Suprel
Surenine
Surrenine
Sus-Phrine
Sus-phrine
Susphrine
Sympathin I
Takamina
Takamine
Tokamina
Tonogen
Twinject
Twinject 0.15
Twinject 0.3
Twinject 0.30
UNII-YKH834O4BH
Vaponefrin
Vasoconstrictine
Vasoconstrictor
Vasodrine
Vasoton
Vasotonin
adrenaline
bmse000316
d-Adrenaline
epinephrine
l-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol
l-Adrenalin
l-Adrenaline
l-Epinephine
l-Epinephrine (synthetic)
l-Epirenamine
l-Methylaminoethanolcatechol
levoepinephrine
nchembio747-comp9
2Racepinephrine834
3
4Epinephryl borate834
5Kavanutraceutical1329000-38-85281052

Interventional clinical trials:

idNameStatusNCT IDPhase
1Auriculotherapy in Tension-type Headache Due to Temporomandibular DysfunctionCompletedNCT02309775
2Sleep Apnea in Early to Mid-Stage Alzheimer's DiseaseRecruitingNCT01400542
3Multi-modal Neuroimaging in Alzheimer's DiseaseActive, not recruitingNCT01554202

Search NIH Clinical Center for Middle Lobe Syndrome


Cochrane evidence based reviews: middle lobe syndrome

Genetic Tests for Middle Lobe Syndrome

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Anatomical Context for Middle Lobe Syndrome

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MalaCards organs/tissues related to Middle Lobe Syndrome:

33
Lung, Brain, Liver, Breast, Endothelial, B cells, Placenta

Animal Models for Middle Lobe Syndrome or affiliated genes

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MGI Mouse Phenotypes related to Middle Lobe Syndrome:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes

Publications for Middle Lobe Syndrome

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Articles related to Middle Lobe Syndrome:

(show top 50)    (show all 95)
idTitleAuthorsYear
1
Can EGFR-Tyrosine Kinase Inhibitors (TKI) Alone Without Talc Pleurodesis Prevent Recurrence of Malignant Pleural Effusion (MPE) in Lung Adenocarcinoma. (27216707)
2016
2
Correction: Relative Importance and Additive Effects of Maternal and Infant Risk Factors on Childhood Asthma. (27219510)
2016
3
Sleep-disordered Breathing in Neuromuscular Disease. (25723731)
2015
4
Malignant pleural and peritoneal mesothelioma consequential to brief indirect asbestos exposure. (25161804)
2014
5
Excessive suicide mortality and risk factors for suicide among patients with heroin dependence. (25456334)
2014
6
Formative research and development of an evidence-based communication strategy: the introduction of Vi typhoid fever vaccine among school-aged children in Karachi, Pakistan. (23330632)
2013
7
Induction of p38I' expression plays an essential role in oncogenic ras-induced senescence. (23878395)
2013
8
Association of angiotensin-converting enzyme gene insertion/deletion polymorphism with decreased risk for basal cell carcinoma. (23299466)
2013
9
Milk fat globule epidermal growth factor 8 serves a novel biomarker of opisthorchiasis-associated cholangiocarcinoma. (24122204)
2013
10
Milk yield and reproductive performance of brucellosis-vaccinated but seropositive Holstein cows. (24254418)
2013
11
Regulation of macrophage migration and activity by high-mobility group boxA 1 protein released from periodontal ligament cells during orthodontically induced periodontal repair: an in vitro and in vivo experimental study. (23974442)
2013
12
Serine 129 phosphorylation of membrane-associated I+-synuclein modulates dopamine transporter function in a G protein-coupled receptor kinase-dependent manner. (23576548)
2013
13
Pathogenesis of human enterovirulent bacteria: lessons from cultured, fully differentiated human colon cancer cell lines. (24006470)
2013
14
Stage-dependent association of BDNF and TGF-I^1 with lung function in stable COPD. (23245944)
2012
15
Posterior arm compartment syndrome after a combined supracondylar humeral and capitellar fractures in an adolescent: a case report. (21415676)
2011
16
Gene expression profiling of human hepatoblastoma using archived formalin-fixed and paraffin-embedded tissues. (21369802)
2011
17
The epidermal growth factor receptor mediates tumor necrosis factor-alpha-induced activation of the ERK/GEF-H1/RhoA pathway in tubular epithelium. (21212278)
2011
18
Does avoidant personality disorder impact on the outcome of treatment for bulimia nervosa? (19536877)
2010
19
Treatment of alopecia areata in children. (19685659)
2009
20
Comparative assessment of a calcium antagonist with controlled release of nifedipine and enalapril in arterial hypertension in subjects older than 60 years]. (19463133)
2009
21
Toxic encephalopathy after taking dried seeds of Datura stramonium in two elderly subjects. (19702945)
2009
22
Cutaneous nocardiosis caused by Nocardia africana on the lower thigh. (18760986)
2009
23
Differential distribution of neuregulin in human brain and spinal fluid. (19150438)
2009
24
Solution structures of cytosolic RNA sensor MDA5 and LGP2 C-terminal domains: identification of the RNA recognition loop in RIG-I-like receptors. (19380577)
2009
25
Predictive value of serum-soluble CD154 in fulminant hepatic failure. (18652769)
2008
26
Identification of two distinct bovine parainfluenza virus type 3 genotypes. (18559934)
2008
27
Clinical relevance of highly sensitive Tg assay in monitoring patients treated for differentiated thyroid cancer. (17555505)
2007
28
Focal acral hyperkeratosis. (17524070)
2007
29
Role of C-reactive protein, D-dimer, and fibrinogen levels in the differential diagnosis of central and peripheral vertigo. (18029334)
2007
30
Insulin sensitivity in patients with primary aldosteronism: a follow-up study. (16822818)
2006
31
Transcriptional factor FOXL2 interacts with DP103 and induces apoptosis. (16153597)
2005
32
Effects of Pro12Ala polymorphism of peroxisome proliferator-activated receptor gamma2 gene on rosiglitazone response in type 2 diabetes. (16084854)
2005
33
Rho GTPase expression in tumourigenesis: evidence for a significant link. (15892119)
2005
34
Unusual tumors associated with the hereditary nonpolyposis colorectal cancer syndrome. (15143336)
2004
35
Nonsyndromic craniosynostosis: diagnosis and contemporary surgical management. (18088747)
2004
36
Nitric oxide negatively regulates proliferation and promotes neuronal differentiation through N-Myc downregulation. (15331636)
2004
37
Identification of a novel COCH mutation, I109N, highlights the similar clinical features observed in DFNA9 families. (11295836)
2001
38
Differential expression and distribution of alpha-, beta-, and gamma-synuclein in the developing human substantia nigra. (11259122)
2001
39
Anti-VEGF antibody treatment of glioblastoma prolongs survival but results in increased vascular cooption. (11005565)
2000
40
Optimal storage conditions for preserving granulocyte viability as monitored by Annexin V binding in whole blood. (10365779)
1999
41
Protein-energy malnutrition in dialysis patients. (9915286)
1999
42
Mutation in the calcium-binding domain of the mitochondrial glycerophosphate dehydrogenase gene in a family of diabetic subjects. (9070847)
1997
43
Are vasopressin peripheral V1 receptors involved in the development of malignant hypertension and stroke in SHR-SPs? (8617411)
1995
44
A genetic approach to elucidating eukaryotic iron metabolism. (7982480)
1994
45
Circumscribed myositis ossificans. Report of nine cases without history of injury. (8237343)
1993
46
A case of acute interstitial nephritis and nonoliguria acute renal failure induced by cimetidine]. (1294777)
1992
47
Immunohistochemical evidence of urokinase-type plasminogen activator in primary and metastatic tumors of pulmonary adenocarcinoma. (2054790)
1991
48
Subacute cutaneous lupus erythematosus: a decade's perspective. (2671533)
1989
49
Physical characterization of the transferrin receptor in human placentae. (6268632)
1981
50
Senear-Usher Syndrome. (19991821)
1939

Variations for Middle Lobe Syndrome

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Expression for genes affiliated with Middle Lobe Syndrome

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Search GEO for disease gene expression data for Middle Lobe Syndrome.

Pathways for genes affiliated with Middle Lobe Syndrome

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Pathways related to Middle Lobe Syndrome according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.5FLNC, VEGFA

GO Terms for genes affiliated with Middle Lobe Syndrome

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Biological processes related to Middle Lobe Syndrome according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1vascular endothelial growth factor receptor signaling pathwayGO:00480109.3JUP, VEGFA
2single organismal cell-cell adhesionGO:00163378.9CDSN, JUP

Sources for Middle Lobe Syndrome

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet