MCID: MDD005
MIFTS: 26

Middle Lobe Syndrome malady

Category: Respiratory diseases

Aliases & Classifications for Middle Lobe Syndrome

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Aliases & Descriptions for Middle Lobe Syndrome:

Name: Middle Lobe Syndrome 11 13 37 66

Classifications:



External Ids:

Disease Ontology11 DOID:2810
SNOMED-CT60 28295001
MeSH37 D008878

Summaries for Middle Lobe Syndrome

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Disease Ontology:11 A lung disease that is defined as a recurrent or chronic collapse of the right middle lobe, right upper lobe or lingula of the lung. it is caused by endobronchial tumour, granulomatous infections, lymphadenopathy, foreign bodies, endobronchial silicotic nodules, inspissated mucus associated with cystic fibrosis or inflammation as a result of an infection.

MalaCards based summary: Middle Lobe Syndrome is related to aspergillosis and allergic bronchopulmonary aspergillosis. An important gene associated with Middle Lobe Syndrome is FLNC (Filamin C), and among its related pathways are Proteoglycans in cancer and Transcription_P53 signaling pathway. Affiliated tissues include lung.

Related Diseases for Middle Lobe Syndrome

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Graphical network of diseases related to Middle Lobe Syndrome:



Diseases related to middle lobe syndrome

Symptoms for Middle Lobe Syndrome

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Drugs & Therapeutics for Middle Lobe Syndrome

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Drugs for Middle Lobe Syndrome (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Epinephrine88651-43-45816
Synonyms:
(-)-(R)-Epinephrine
(-)-3,4-Dihydroxy-a-[2-(methylamino)ethyl]benzyl alcohol
(-)-3,4-Dihydroxy-alpha-((methylamino)methyl)benzyl alcohol
(-)-3,4-Dihydroxy-alpha-[2-(methylamino)ethyl]benzyl alcohol
(-)-3,4-dihydroxy-a-[(methylamino)methyl]-Benzyl alcohol
(-)-3,4-dihydroxy-alpha-[(methylamino)methyl]-Benzyl alcohol
(-)-Adrenalin
(-)-Adrenaline
(-)-Epinephrine
(-)-R-Epinephrine
(R)-(-)-Adnephrine
(R)-(-)-Adrenaline
(R)-(-)-Epinephrine
(R)-(-)-Epirenamine
(R)-(−)-adrenaline
(R)-4-[1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol
(R)-4-[1-hydroxy-2-(methylamino)ethyl]-1,2-Benzenediol
(R)-Adrenaline
(R)-Epinephrine
(−)-adrenaline
02252_FLUKA
1-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol
1-Adrenalin
1-Epinephrine
4-(1-Hydroxy-2-(methylamino)ethyl)-1,2-benzenediol
4-(1-hydroxy-2-methylamino-ethyl)benzene-1,2-diol
4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-1,2-Benzenediol
4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol
4-[(1R)-1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol
51-43-4
51-43-4 (FREE BASE)
51028-73-0
A0173
AC-13188
AC1L1L7B
ADR ADRENALINE
ADROP
AI3-19015
Adnephrine
Adrenal
Adrenalin
Adrenalin (TN)
Adrenalin in Oil
Adrenalin-Medihaler
Adrenalina
Adrenalina [DCIT]
Adrenaline
Adrenaline (JP15)
Adrenaline/Epinephrine
Adrenalinum
Adrenamine
Adrenan
Adrenapax
Adrenasol
Adrenatrate
Adrenine
Adrenodis
Adrenohorma
Adrenosan
Adrenutol
Adrin
Adrine
Ana-Guard
Ana-Kit
Antiasthmatique
Asmatane Mist
Asthma meter mist
Asthma-nefrin
Asthmahaler Mist
Asthmanefrin
Astmahalin
Astminhal
BIDD:GT0119
Balmadren
Bernarenin
Biorenine
Bosmin
Brevirenin
Bronkaid
Bronkaid Mist
Bronkaid Suspension Mist
Bupivacaine Hcl and Epinephrine
C00788
CCRIS 4812
CHEBI:28918
CHEMBL679
CID5816
Chelafrin
Citanest Forte
Corisol
D-Epifrin
D-Epinephrine
D00095
DB00668
Drenamist
Dylephrin
Dyspne-Inhal
E4250_SIGMA
EINECS 200-098-7
EPI E Z PEN JR
EPIPEN E Z PEN
EPIPEN JR
Epi EZ Pen Jr
Epifrin
Epiglaufrin
Epinefrin
Epinefrin [Czech]
Epinefrina
Epinefrina [INN-Spanish]
Epinephran
Epinephrin
Epinephrine
Epinephrine (USP)
Epinephrine (USP/INN)
Epinephrine [USAN:INN:JAN]
Epinephrine hydrochloride
Epinephrinum
Epinephrinum [INN-Latin]
Epipen
Epipen (TN)
Epipen Auto-Injector
Epipen EZ Pen
Epipen Jr.
Epipen Jr. Auto-Injector
Epirenamine
Epirenan
Epirenin
Epitrate
Eppy
Esphygmogenina
Exadrin
 
Glaucon
Glaucosan
Glauposine
Glycirenan
HSCI1_000215
HSDB 4289
Haemostasin
Haemostatin
Hektalin
Hemisine
Hemostasin
Hemostatin
Hypernephrin
Hyporenin
IOP
Intranefrin
Iontocaine
Isoptoepinal
Kidoline
L-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol
L-Adrenaline
L-Adrenaline Base
L-Epinehphrine
L-Epinephrine
L-Epirenamine
L-Methylaminoethanolcatechol
L-epinephrine
LS-156
Levo-Methylaminoethanolcatechol
Levoadrenaline
Levoepinephrine
Levorenen
Levorenin
Levorenine
Levoreninum
Lopac-E-4642
Lyodrin
Lyophrin
Medihaler-Epi
Metanephrin
Methylaminoethanolcatechol
Methylarterenol
Micronefrin
Micronephrine
MolPort-002-051-368
Mucidrina
Myosthenine
Mytrate
NCGC00015417-01
NCGC00142615-01
NCGC00142615-03
NCGC00142615-04
NCGC00142615-05
NCGC00142615-06
NCGC00142615-07
NSC 62786
NSC62786
Nephridine
Nieraline
PDSP1_001120
PDSP2_001104
Paranephrin
Primatene
Primatene Mist
R-(-)-Epinephrine
R-Adrenaline
RCRA waste no. P042
Racemic Epinephrine
Racepinephrine
Rcra waste number P042
Renagladin
Renaglandin
Renaglandulin
Renaleptine
Renalina
Renoform
Renostypricin
Renostypticin
Renostyptin
SMP1_000227
ST069368
SUS-PHRINE SULFITE-FREE
Scurenaline
Septocaine
Simplene
Sindrenina
Soladren
Sphygmogenin
Stryptirenal
Styptirenal
Supracapsulin
Supradin
Supranefran
Supranephrane
Supranephrine
Supranol
Suprarenaline
Suprarenin
Suprel
Surenine
Surrenine
Sus-Phrine
Sus-phrine
Susphrine
Sympathin I
Takamina
Takamine
Tokamina
Tonogen
Twinject
Twinject 0.15
Twinject 0.3
Twinject 0.30
UNII-YKH834O4BH
Vaponefrin
Vasoconstrictine
Vasoconstrictor
Vasodrine
Vasoton
Vasotonin
adrenaline
bmse000316
d-Adrenaline
epinephrine
l-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol
l-Adrenalin
l-Adrenaline
l-Epinephine
l-Epinephrine (synthetic)
l-Epirenamine
l-Methylaminoethanolcatechol
levoepinephrine
nchembio747-comp9
2
Ethanol197164-17-5702
Synonyms:
(C6-C9)Alkyl alcohol
02483_FLUKA
02851_FLUKA
02853_FLUKA
02854_FLUKA
02855_FLUKA
02856_FLUKA
02856_SIAL
02857_FLUKA
02857_SIAL
02858_FLUKA
02858_SIAL
02860_FLUKA
02865_FLUKA
02865_SIAL
02870_FLUKA
02870_SIAL
02875_FLUKA
02877_FLUKA
02878_FLUKA
02882_FLUKA
02882_SIAL
02883_FLUKA
02884_FLUKA
02890_FLUKA
02890_SIAL
02891_FLUKA
02891_SIAL
1-Hydroxyethane
100C.NPA
121182-78-3
187380_ALDRICH
187380_SIAL
24102_RIEDEL
24102_SIAL
24103_RIEDEL
24103_SIAL
24105_RIEDEL
24105_SIAL
24106_RIEDEL
24106_SIAL
24194_RIEDEL
24194_SIAL
245119_ALDRICH
245119_SIAL
270741_ALDRICH
270741_SIAL
277649_ALDRICH
277649_SIAL
2858_SIGMA
29221_FLUKA
32205_RIEDEL
32205_SIAL
32221_RIEDEL
32221_SIAL
32294_RIEDEL
32294_SIAL
34870_SIAL
34963_RIEDEL
39278_FLUKA
40210_ALDRICH
40210_RIEDEL
41322_FLUKA
458600_ALDRICH
458600_SIAL
459828_ALDRICH
459828_SIAL
459836_ALDRICH
459836_SIAL
459844_SIAL
48075_SUPELCO
493511_SIAL
493538_ALDRICH
493538_SIAL
493546_ALDRICH
493546_SIAL
64-17-5
676829_SIAL
68475-56-9
71076-86-3
71329-38-9
8000-16-6
8024-45-1
AC1L19TW
AC1Q31MM
AHD 2000
AI3-01706
ALCOHOL 5% IN D5-W
Absolute Alcohol
Absolute Ethanol
Absolute alcohol
Absolute ethanol
Absolute ethyl alcohol
Aethanol
Aethanol [German]
Aethylalkohol
Alcare Hand Degermer
Alcohol
Alcohol (USP)
Alcohol (ethyl)
Alcohol Anhydrous
Alcohol [USP]
Alcohol anhydrous
Alcohol dehydrated
Alcohol denatured
Alcohol etílico
Alcohol, Absolute
Alcohol, Dehydrated
Alcohol, Diluted
Alcohol, Grain
Alcohol, anhydrous
Alcohol, dehydrated
Alcohol, denatured
Alcohol, diluted
Alcohol, ethyl
Alcohols
Alcohols, C1-3
Alcohols, C30
Alcohols, C6-9
Alcool Ethylique
Alcool Etilico
Alcool ethylique
Alcool etilico
Alcool éthylique
Algrain
Alkohol
Alkohol [German]
Alkoholu Etylowego
Alkoholu etylowego
Aminoethanol
Anhydrol
Anhydrol PM 4085
Anhydrous alcohol
Anhydrous ethanol
Beta-Aminoethanol
Beta-Aminoethyl Alcohol
Beta-Ethanolamine
Beta-Hydroxyethylamine
C00469
C2H5OH
C2H6O
CCRIS 945
CDA 19
CDA 19-200
CHEBI:16236
CHEMBL545
CID702
Caswell No. 426
Caswell No. 430
Colamine
Cologne Spirit
Cologne spirit
Cologne spirits
 
D000431
D00068
DB00898
Dehydrated Ethanol
Dehydrated alcohol
Dehydrated ethanol
Denatured Alcohol
Denatured Alcohol Cd-10
Denatured Alcohol Cd-5
Denatured Alcohol Cd-5a
Denatured Alcohol Sd-1
Denatured Alcohol Sd-13a
Denatured Alcohol Sd-17
Denatured Alcohol Sd-23a
Denatured Alcohol Sd-28
Denatured Alcohol Sd-30
Denatured Alcohol Sd-39b
Denatured Alcohol Sd-39c
Denatured Alcohol Sd-3a
Denatured Alcohol Sd-40m
Denatured Ethanol
Denatured alcohol
Denatured ethanol
Desinfektol EL
Diluted Alcohol
Distilled spirits
E2385_SIGMA
E7023_ALDRICH
E7023_SIAL
E7148_ALDRICH
E7148_SIAL
E7517_SIGMA
EINECS 200-578-6
EINECS 270-649-4
EOH
EOX
ETA
Envision Conditioner Pdd 9020
Esumiru WK 88
EtOH
Etanolo
Etanolo [Italian]
Ethanol (9CI)
Ethanol 200 Proof
Ethanol 200 proof
Ethanol Absolute
Ethanol Absolute Bp
Ethanol Anhydrous
Ethanol Extra Pure
Ethanol Vapor
Ethanol [JAN]
Ethanol solution
Ethanol, Silent Spirit
Ethanol, undenatured
Ethanolum anhydricum
Ethicap
Ethyl Alcohol
Ethyl Alcohol & Water, 10%
Ethyl Alcohol & Water, 20%
Ethyl Alcohol & Water, 30%
Ethyl Alcohol & Water, 40%
Ethyl Alcohol & Water, 5%
Ethyl Alcohol & Water, 50%
Ethyl Alcohol & Water, 60%
Ethyl Alcohol & Water, 70%
Ethyl Alcohol & Water, 80%
Ethyl Alcohol & Water, 95%
Ethyl Alcohol & Water, 96%
Ethyl Alcohol Anhydrous
Ethyl Alcohol, Anhydrous
Ethyl Alcohol, Denatured
Ethyl Hydrate
Ethyl Hydroxide
Ethyl alc
Ethyl alcohol
Ethyl alcohol anhydrous
Ethyl alcohol in alcoholic beverages
Ethyl alcohol usp
Ethyl hydrate
Ethyl hydroxide
Ethylalcohol
Ethylalcohol [Dutch]
Ethylol
Ethylolamine
Ethyloxy Group
Etylowy alkohol
FEMA No. 2419
FEMA Number 2419
Fermentation alcohol
Glycinol
Grain alcohol
HSDB 531
HSDB 82
HYDROXYETHYL GROUP
Hinetoless
Hydroxyethane
I14-12648
IMS 99
Infinity Pure
Jaysol
Jaysol S
LS-1539
LTBB002977
Lux
Methylated Spirit Mineralised
Methylated spirit
Methylcarbinol
MolPort-001-785-844
Molasses alcohol
NCGC00091458-01
NCI-C03134
NSC 85228
NSC85228
Oxydimethylene Group
Potato alcohol
Punctilious ethyl alcohol
Pyro
QMHAIh@
Reagent Alcohol
Ru-Tuss Expectorant
SDA 3A
SDA 40-2
SDM No. 37
SY Fresh M
Sekundasprit
Silent spirit
Spirit
Spirits of wine
Spiritus vini
Spirt
Synasol
Tecsol
Tecsol C
Thanol
Thiofaco M-50
UNII-3K9958V90M
USAF EK-1597
Undenatured Ethanol
WLN: Q2
absolute alcohol
alcohol
alcohol etilico
bmse000297
etanol
ethanol
ethyl alcohol
grain alcohol
nchem.651-comp3c
nchembio.552-comp10
nchembio.94-comp20
spiritus vini
Äthanol
Äthylalkohol
éthanol
3KavaNutraceutical1379000-38-8

Interventional clinical trials:

idNameStatusNCT IDPhase
1Auriculotherapy in Tension-type Headache Due to Temporomandibular DysfunctionCompletedNCT02309775
2Multi-modal Neuroimaging in Alzheimer's DiseaseActive, not recruitingNCT01554202
3Sleep Apnea in Early to Mid-Stage Alzheimer's DiseaseTerminatedNCT01400542

Search NIH Clinical Center for Middle Lobe Syndrome


Cochrane evidence based reviews: middle lobe syndrome

Genetic Tests for Middle Lobe Syndrome

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Anatomical Context for Middle Lobe Syndrome

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MalaCards organs/tissues related to Middle Lobe Syndrome:

34
Lung

Animal Models for Middle Lobe Syndrome or affiliated genes

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Publications for Middle Lobe Syndrome

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Articles related to Middle Lobe Syndrome:

(show top 50)    (show all 97)
idTitleAuthorsYear
1
Childhood allergic bronchopulmonary aspergillosis presenting as a middle lobe syndrome. (26844222)
2016
2
Middle lobe syndrome: a singularly rare presentation of complicated pulmonary hydatid disease. (27045051)
2016
3
Middle lobe syndrome in children today. (24630779)
2014
4
Middle lobe syndrome: a review of clinicopathological features, diagnosis and treatment. (22377566)
2012
5
Surgical treatment of right middle lobe syndrome in children. (22347343)
2012
6
Chronic atelectasis of the left lower lobe: a clinicopathological condition equivalent to middle lobe syndrome. (22761114)
2012
7
Bronchial anthracofibrosis and tuberculosis presenting as a middle lobe syndrome. (18253679)
2008
8
Endobronchial tuberculosis presenting as right middle lobe syndrome: clinical characteristics and bronchoscopic findings in 22 cases. (18729304)
2008
9
Bronchial hyperresponsiveness in persistent middle lobe syndrome in childhood. (17256771)
2007
10
Bronchial hyperresponsiveness, atopy, and bronchoalveolar lavage eosinophils in persistent middle lobe syndrome. (16845656)
2006
11
Editorial: respecting the middle lobe syndrome. (16845655)
2006
12
The role of timely intervention in middle lobe syndrome in children. (16236916)
2005
13
Not the right middle lobe syndrome? (9254755)
1997
14
The right middle-lobe syndrome--a case report and review of the literature. (9107229)
1997
15
Middle lobe syndrome. (8644568)
1996
16
Right middle lobe syndrome caused by Mycobacterium fortuitum in a patient with human immunodeficiency virus infection. (1631699)
1992
17
Peripheral middle lobe syndrome. (6611925)
1983
18
Middle lobe syndrome. (6344820)
1983
19
Middle lobe syndrome: diagnosis and management. (7065761)
1982
20
Traction diverticula of the esophagus in the middle lobe syndrome. (6786722)
1981
21
Isolated middle lobe atelectasis: aetiology, pathogenesis, and treatment of the so-called middle lobe syndrome. (7434301)
1980
22
Middle lobe syndrome as an unusual presentation of metastatic osteogenic sarcoma. (6932272)
1980
23
Middle lobe syndrome secondary to allergic bronchopulmonary aspergillosis. (7369555)
1980
24
Middle lobe syndrome. (7430667)
1980
25
Collateral ventilation and the middle lobe syndrome. (697180)
1978
26
The middle lobe syndrome and its quasi variants. (4810669)
1974
27
Etiology and surgical management of the middle lobe syndrome. (4731501)
1973
28
Middle lobe syndrome in asthmatic children. (5012331)
1972
29
Middle lobe syndrome and intractable asthma. (5532652)
1970
30
Middle lobe syndrome. (4996247)
1970
31
The so-called middle lobe syndrome. Diagnosis and results of treatment. (5487050)
1970
32
Middle-lobe syndrome following pneumonitis due to retention of bronchographic contrast medium. (5670923)
1968
33
The middle lobe syndrome: a clinical study. (5953791)
1966
34
Psittacosis as a cause of middle lobe syndrome: report of two cases. (13900719)
1962
35
The correlation of bronchoscopic and bronchographic findings in the middle lobe syndrome. (13635712)
1958
36
The correlation of bronchoscopic and bronchographic findings in the middle lobe syndrome. (13572232)
1958
37
Bilateral middle lobe syndrome. (13512135)
1958
38
Middle lobe syndrome in a three year old child treated with lobectomy. (13473348)
1957
39
Middle lobe syndrome. (13467312)
1957
40
Middle lobe syndrome. (13308584)
1956
41
Middle lobe syndrome due to sarcoidosis. (13356739)
1956
42
The middle lobe syndrome; a review of the anatomic and clinical features. (14376795)
1955
43
Middle lobe syndrome. (14380564)
1955
44
Nontuberculous pulmonary disease: the middle lobe syndrome: anatomic and clinical features. (13216865)
1954
45
Middle lobe syndrome produced by foreign body in lower third of esophagus. (13044637)
1953
46
Obstructive pneumonitis of the middle lobe; the middle lobe syndrome. (14906913)
1952
47
Middle lobe syndrome. (14929173)
1952
48
Nonspecific pneumonitis of the left upper lobe ( simulating the middle lobe syndrome and producing an early superior pulmonary sulcus syndrome). (14804710)
1951
49
The middle lobe syndrome. (14814491)
1951
50
Middle lobe syndrome. (18874043)
1948

Variations for Middle Lobe Syndrome

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Expression for genes affiliated with Middle Lobe Syndrome

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Search GEO for disease gene expression data for Middle Lobe Syndrome.

Pathways for genes affiliated with Middle Lobe Syndrome

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Pathways related to Middle Lobe Syndrome according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.5FLNC, VEGFA
29.5FLNC, VEGFA

GO Terms for genes affiliated with Middle Lobe Syndrome

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Cellular components related to Middle Lobe Syndrome according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1Z discGO:00300189.7FLNC, JUP
2cell-cell junctionGO:00059119.1CDSN, JUP
3desmosomeGO:00300578.8CDSN, JUP

Biological processes related to Middle Lobe Syndrome according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1single organismal cell-cell adhesionGO:00163379.1CDSN, JUP

Molecular functions related to Middle Lobe Syndrome according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1structural molecule activityGO:00051989.7JUP, KRT74
2protein homodimerization activityGO:00428038.6CDSN, JUP, VEGFA

Sources for Middle Lobe Syndrome

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet