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MCID: MGR002
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Migraine malady |
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Sources: 6Disease Ontology, 23MedlinePlus, 31NINDS, 44Wikipedia, 33OMIM, 22MalaCards See all sources Export this MalaCard |
NINDS: The pain of a migraine headache is often described as an intense pulsing or throbbing pain in one area of the head. However,
it is much more; the International Headache Society diagnoses a migraine by its pain and number of attacks (at least 5, lasting
4-72 hours if untreated), and additional symptoms including nausea and/or vomiting, or sensitivity to both light and sound.
Migraine is three times more common in women than in men and affects more than 10 percent of people worldwide. Roughly one-third
of affected individuals can predict the onset of a migraine because it is preceded by an "aura," visual disturbances that
appear as flashing lights, zig-zag lines or a temporary loss of vision. People with migraine tend to have recurring attacks
triggered by a number of different factors, including stress, anxiety, hormonal changes, bright or flashing lights, lack of
food or sleep, and dietary substances. 31
MalaCards: Migraine, also known as migraine variant, is related to migraine with aura and hemiplegic migraine. An important gene associated with Migraine is ATP1A2 (ATPase, Na+/K+ transporting, alpha 2 polypeptide), and among its related pathways are Neuroactive ligand-receptor interaction and Amine ligand-binding receptors. The compounds glutamine and 5-hydroxytryptamine have been mentioned in the context of this disorder. Affiliated tissues include brain, small intestine and kidney, and related mouse phenotypes are cellular and respiratory system. Disease Ontology: A brain disease that is characterized by moderate to severe headaches, nausea, extreme sensitivity to light and sound and intense unilaterial throbbing or pulsing.6 MedlinePlus: If you suffer from migraine headaches, you're not alone. about 12 percent of the u.s. population gets them. migraines are recurring attacks of moderate to severe pain. the pain is throbbing or pulsing, and is often on one side of the head. during migraines, people are very sensitive to light and sound. they may also become nauseated and vomit. migraine is three times more common in women than in men. some people can tell when they are about to have a migraine because they see flashing lights or zigzag lines or they temporarily lose their vision. many things can trigger a migraine. these include anxiety stress lack of food or sleep exposure to light hormonal changes (in women) doctors used to believe migraines were linked to the opening and narrowing of blood vessels in the head. now they believe the cause is related to genes that control the activity of some brain cells. medicines can help prevent migraine attacks or help relieve symptoms of attacks when they happen. for many people, treatments to relieve stress can also help. nih: national institute of neurological disorders and stroke23 Wikipedia: Migraine is a chronic neurological disorder characterized by recurrent moderate to severe headaches...44 more... OMIM: 157300 |
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Sources: 6Disease Ontology, 7diseasecard, 17Genetics Home Reference, 31NINDS, 8DISEASES, 33OMIM, 32Novoseek , 23MedlinePlus, 43UMLS, 40SNOMED-CT, 24MeSH See all sources |
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Sources: 33OMIM See all sources |
Clinical features from OMIM: 157300
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Sources: 4CenterWatch, 29NIH Clinical Center, 5ClinicalTrials, 43UMLS, 28NDF-RT See all sources |
Approved drugs:Search CenterWatch for migraine Drug clinical trials:Search ClinicalTrials for migraine Search NIH Clinical Center for migraine Search CenterWatch for migraine |
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Sources: 22MalaCards See all sources |
MalaCards organs/tissues related to migraine:22Brain, Small intestine, Kidney, Liver, Monocytes, Nk cells, T cells, B cells, Endothelial, Thalamus, Hypothalamus, Pituitary
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Sources: 25MGI See all sources |
MGI Mouse Phenotypes related to migraine:25 (show all 25)
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Sources: 35PubMed See all sources |
Articles related to migraine:(show top 50) (show all 592)
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Sources: 1BioGPS See all sources |
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Sources: 20KEGG, 38Reactome, 36QIAGEN, 34PharmGKB, 41Thomson Reuters, 10EMD Millipore See all sources |
Pathways related to migraine according to GeneDecks:(show top 50) (show all 107)
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Sources: 32Novoseek , 9DrugBank, 18HMDB, 34PharmGKB, 42Tocris Bioscience See all sources |
Compounds related to migraine according to GeneDecks:(show top 50) (show all 584)
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Sources: 12Gene Ontology See all sources |
Cellular components related to migraine according to GeneDecks:
Biological processes related to migraine according to GeneDecks:(show top 50) (show all 62)
Molecular functions related to migraine according to GeneDecks:(show all 10)
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