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MCID: MGR003

Migraine with Aura malady
32 genes, 2 tissues, 309 related diseases, 15 phenotypes, 35 articles, clinical trials.

Summaries for Migraine with Aura

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17Genetics Home Reference, 44Wikipedia, 22MalaCards
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Genetics Home Reference: Familial hemiplegic migraine (FHM) is a form of migraine headache that runs in families. Migraines usually cause intense, throbbing pain in one area of the head, often accompanied by nausea, vomiting, and extreme sensitivity to light and sound. These recurrent headaches typically begin in childhood or adolescence and can be triggered by certain foods, emotional stress, and minor head trauma. Each headache may last from a few hours to a few days.17

MalaCards: Migraine with Aura, also known as classic migraine, is related to familial hemiplegic migraine and hemiplegic migraine. An important gene associated with Migraine with Aura is EPOLM (epilepsy, occipitotemporal lobe, and migraine with aura), and among its related pathways are Selective Serotonin Reuptake Inhibitor Pathway, Pharmacodynamics and Endothelin-1 Signaling Pathway. The compounds yohimbine and bromocriptine have been mentioned in the context of this disorder. Affiliated tissues include brain and endothelial, and related mouse phenotypes are endocrine/exocrine gland and embryogenesis.

Wikipedia: An aura is a perceptual disturbance experienced by some migraine sufferers before a migraine headache,...44 more...

Aliases & Descriptions for Migraine with Aura

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6Disease Ontology, 43UMLS, 8DISEASES, 40SNOMED-CT, 19ICD9CM, 24MeSH
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Aliases & Descriptions:

migraine with aura 6 43
classic migraine 6 8
migraine disorders 43

External Ids:

ICD9CM19 346.0
SNOMED-CT40 4473006, 155047002

Related Diseases for Migraine with Aura

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13GeneCards, 14GeneDecks
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Disease types for migraine with aura family:

migraine with aura 7 migraine with aura 9

Diseases related to migraine with aura by text searches and GeneDecks gene sharing:

(show top 50)    (show all 304)
idRelated DiseaseScoreTop Affiliating Genes
1familial hemiplegic migraine33.0SCN1A, ATP1A2, MGR5, CACNA1A
2hemiplegic migraine32.4SCN1A, ATP1A2, CACNA1A
3migraine without aura31.2KCNK18, MGR5, MA
4cadasil26.0VIP, MTHFR, F5, HTR2A, NOS3, NOTCH3
5twinning25.7SCN1A, MTHFR, INSR, F5, DRD2, NOTCH3
6toxic epidermal necrolysis13.5EDNRA, EDNRB
7alternating hemiplegia of childhood13.4ATP1A2, CACNA1A, SLC2A1
8myoclonic astatic epilepsy13.4SCN1A, SLC2A1
9conduct disorder13.4HTR1B, SLC6A4
10phobia13.3DRD2, SLC6A4, ADORA2A
11transient cerebral ischemia13.3MTHFR, NOTCH3
12leptin receptor deficiency13.3DRD2, SLC6A3
13convulsions13.2SCN1A, ATP1A2, CACNA1A, DBH
14binswanger's disease13.2VIP, NOTCH3
15hemiplegia13.2SCN1A, ATP1A2, CACNA1A, SLC2A1
16neurotic disorder13.2HTR2A, DRD2, SLC6A4
17tic disorder13.2HTR2A, DRD2
18generalized anxiety disorder13.2HTR2A, HTR2C, SLC6A4
19seasonal affective disorder13.2HTR2A, HTR2C, SLC6A4
20multiple chemical sensitivity13.2VIP, MTHFR, SLC6A4
21conduction disease13.1DBH, SLC6A3, SLC6A4
22intracranial hypertension13.1ATP1A2, F5, CACNA1A
23insomnia13.1HTR2A, HTR2C, SLC6A4
24autistic disorder13.1HTR2A, DBH, SLC6A4, GABRA5
25alcoholic psychosis13.1HTR2A, SLC6A3, SLC6A4
26pathological gambling13.1DRD2, SLC6A3, SLC6A4
27constipation13.1VIP, EDNRB, DBH, SLC6A4
28insulin autoimmune syndrome13.1INSR, F5
29opiate dependence13.1DRD2, SLC6A3, SLC6A4
30antisocial personality disorder13.1HTR1B, HTR2A, DRD2, SLC6A4
31gilles de la tourette syndrome13.1DRD2, DBH, SLC6A3
32gestational diabetes13.0INSR, DBH, SLC2A1
33blood protein disease13.0MTHFR, F5
34megacolon13.0VIP, HTR2A, DRD2, EDNRB
35hyperprolactinemia13.0VIP, HTR2A, DRD2, DBH
36bulimia nervosa13.0HTR1B, HTR2A, HTR2C, SLC6A4
37bipolar i disorder13.0HTR2A, DRD2, SLC6A4, GABRA5
38manic-depressive illness13.0DRD2, DBH, SLC6A3, SLC6A4
39personality disorder13.0HTR1B, DRD2, SLC6A3, SLC6A4
40eating disorder13.0HTR2A, SLC6A3, SLC6A4
41cocaine abuse13.0DRD2, DBH, SLC6A3, SLC6A4
42premature ejaculation13.0HTR1B, HTR2C, SLC6A3, SLC6A4
43myoclonus12.9HTR1D, HTR2A, HTR2C, DRD2
44hepatic vein thrombosis12.9MTHFR, F5
45restless legs syndrome12.9CACNA1A, DRD2, SLC6A3, SLC6A4
46spinal cord infarction12.9MTHFR, F5
47movement disease12.9DRD2, SLC6A3, SLC2A1
48idiopathic generalized epilepsy12.9SCN1A, ATP1A2, CACNA1A
49amaurosis fugax12.9MTHFR, F5
50substance dependence12.9HTR1B, DRD2, SLC6A3, SLC6A4

Graphical network of the top 20 diseases related to migraine with aura:



Graphical network of diseases related to migraine with aura

Clinical Features for Migraine with Aura

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Drugs & Therapeutics for Migraine with Aura

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4CenterWatch, 29NIH Clinical Center, 5ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Migraine with Aura

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Anatomical Context for Migraine with Aura

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22MalaCards
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MalaCards organs/tissues related to migraine with aura:

22
Brain, Endothelial

Phenotypes for genes affiliated with Migraine with Aura

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25MGI
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MGI Mouse Phenotypes related to migraine with aura:

25 (show all 15)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1endocrine/exocrine gland phenotypeMP:00053799.7DBH, EDNRA, HTR2A, HTR1B
2embryogenesis phenotypeMP:00053809.6EDNRB, SPTAN1, ATP1A2
3reproductive system phenotypeMP:00053899.0SLC6A3, NOTCH3, DRD2, CACNA1A, HTR1B, SCN1A
4skeleton phenotypeMP:00053908.5GABRA5, EDNRB, DRD2, ESR1, HTR1B, MTHFR
5no phenotypic analysisMP:00030128.1SLC2A1, EDNRB, DRD2, ESR1, CACNA1A, MTHFR
6integument phenotypeMP:00107717.9ADORA2A, SLC6A4, SLC6A3, DBH, EDNRB, DRD2
7respiratory system phenotypeMP:00053887.4EDNRB, EDNRA, NOTCH3, NOS3, DRD2, ESR1
8renal/urinary system phenotypeMP:00053676.9ACE, EDNRB, EDNRA, EDN1, NOTCH3, NOS3
9growth/size phenotypeMP:00053786.3EDNRB, ACE, DBH, SLC6A3, SLC2A1, SLC6A4
10muscle phenotypeMP:00053695.9NOTCH3, EDN1, EDNRA, EDNRB, SLC6A3, SLC6A4
11nervous system phenotypeMP:00036315.8KCNK18, ADORA2A, SLC6A4, SLC2A1, SLC6A3, DBH
12cardiovascular system phenotypeMP:00053855.4EDN1, EDNRA, EDNRB, ACE, DBH, SLC6A4
13behavior/neurological phenotypeMP:00053864.4NOS3, EDNRB, ACE, DBH, SLC6A3, SLC2A1
14homeostasis/metabolism phenotypeMP:00053764.1EDN1, EDNRA, EDNRB, ACE, DBH, SLC6A3
15mortality/agingMP:00107684.0NOTCH3, EDN1, EDNRA, EDNRB, ACE, DBH

Publications for genes affiliated with Migraine with Aura

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35PubMed
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Articles related to migraine with aura:

(show all 35)
idTitleAuthorsYearAffiliating Genes
1Association of the A-1438G polymorphism in serotonin 2A receptor in migraine with aura among Japanese patients. (20930387)Naito Y.... Kiuchi Y.2010HTR2A
2A dominant-negative mutation in the TRESK potassium channel is linked to familial migraine with aura. (20871611)Lafreniere R.G.... Rouleau G.A.2010KCNK18
3Paroxysmal exercise-induced dyskinesia, writer's cramp, migraine with aura and absence epilepsy in twin brothers with a novel SLC2A1 missense mutation. (20621801)Urbizu A.... Macaya A.2010SLC2A1
4New genetic evidence for involvement of the dopamine system in migraine with aura. (19152006)Todt U.... Kubisch C.2009DBH, DRD2, SLC6A3
5Mutation of MTHFR gene as marker of endothelial dysfunction in patients diagnosed of migraine with aura. (19344796)HernA!ndez T.I.... Del Carmen GarcA-a Garay M.2009MTHFR
6Identification of biomarkers associated with migraine with aura. (19428688)Nagata E.... Takagi S.2009SPTAN1
7Genetic association study of endothelin-1 and its rec eptors EDNRA and EDNRB in migraine with aura. (19558538)Tikka-Kleemola P.... Kallela M.2009EDNRB, EDNRA, EDN1
8Genetic association studies of the chromosome 15 GABA-A receptor cluster in migraine with aura. (17680603)Netzer C.... Kubisch C.2008GABRA5
9Replication study of the insulin receptor gene in migraine with aura. (18455362)Netzer C.... Kubisch C.2008INSR
10An adenosine A2A receptor gene haplotype is associated with migraine with aura. (17257240)Hohoff C.... Mossner R.2007ADORA2A, VIP
11The CACNA1A and ATP1A2 genes are not involved in dominantly inherited migraine with aura. (16508934)Kirchmann M.... Olesen J.2006ATP1A2, CACNA1A
12Haplotype-based systematic association studies of ATP1A2 in migraine with aura. (16508935)Netzer C.... Kubisch C.2006ATP1A2
13Endothelial nitric oxide synthase (Glu298Asp) polymorphism is an independent risk factor for migraine with aura. (17115991)Borroni B.... Padovani A.2006NOS3
14Testing of variants of the MTHFR and ESR1 genes in 1798 Finnish individuals fails to confirm the association with migraine with aura. (17116097)Kaunisto M.A.... Wessman M.2006ESR1, MTHFR
15Association between a 19 bp deletion polymorphism at the dopamine beta-hydroxylase (DBH) locus and migraine with aura. (17095019)Fernandez F.... Griffiths L.R.2006DBH
16Variation of the serotonin transporter gene SLC6A4 in the susceptibility to migraine with aura. (17101915)Todt U.... Kubisch C.2006SLC6A4
17A functional serotonin transporter gene polymorphism is associated with migraine with aura. (15642926)Marziniak M.... Sommer C.2005SLC6A4
18Chromosome 19p13 loci in Finnish migraine with aura families. (15449251)Kaunisto M.A.... Wessman M.2005CACNA1A
19Functional serotonin 5-HTTLPR polymorphism is a risk factor for migraine with aura. (16362658)Borroni B.... Padovani A.2005SLC6A4
20A new susceptibility locus for migraine with aura in the 15q11-q13 genomic region containing three GABA-A receptor genes. (15586324)Russo L.... Gurrieri F.2005MGR7
21Association of the insertion/deletion polymorphism of the angiotensin I-converting enzyme gene in patients of migraine with aura. (15644278)Kowa H.... Nakashima K.2005ACE
22Serotonin 2C receptor gene Cys23Ser polymorphism: a candidate genetic risk factor of migraine with aura in Japanese population. (15147464)Kusumi M.... Nakashima K.2004HTR2C
23Migraine aura: new information on underlying mechanisms. (15167063)SA!nchez-del-Rio M.... Reuter U.2004CACNA1A
24Migraine with aura and brain magnetic resonance imaging abnormalities in patients with CADASIL. (15313840)Vahedi K.... Bousser M.G.2004NOTCH3
25The methylenetetrahydrofolate reductase gene variant C677T influences susceptibility to migraine with aura. (15053827)Lea R.A.... Griffiths L.R.2004MTHFR
26Familial migraine with aura: association study with 5-HT1B/1D, 5-HT2C, and hSERT polymorphisms. (15109354)Racchi M.... Bussone G.2004HTR2C, HTR1B, HTR1D
27Significant linkage to migraine with aura on chromosome 11q24. (12915447)Cader Z.M.... Ebers G.C.2003ATP1A2, CACNA1A, MA
28A susceptibility locus for migraine with aura, on chromosome 4q24. (11836652)Wessman M.... Palotie A.2002MA
29Migraine with aura is not linked to the FHM gene CACNA1A or the chromosomal region, 19p13. (12370474)Noble-Topham S.E.... Ebers G.C.2002CACNA1A
30Migraine with aura susceptibility locus on chromosome 19p13 is distinct from the familial hemiplegic migraine locus. (11735221)Jones K.W.... Peroutka S.J.2001MGR5
31Migraine with aura and white matter abnormalities: Notch3 mutation. (10802804)Ceroni M.... Carrera P.2000NOTCH3
32Comorbid migraine with aura, anxiety, and depression is associated with dopamine D2 receptor (DRD2) NcoI alleles. (9513185)Peroutka S.J.... Jones K.W.1998DRD2
33Altered allelic distributions of the serotonin transporter gene in migraine without aura and migraine with aura. (9601620)Ogilvie A.D.... Olesen J.1998SLC6A4
34Genetic abnormalities of the protein C system: shared risk factors in young adults with migraine with aura and with ischemic stroke? (9876885)D'Amico D.... Bussone G.1998F5
35Clinical susceptibility to migraine with aura is modified by dopamine D2 receptor (DRD2) NcoI alleles. (9222191)Peroutka S.J.... Jones K.1997DRD2

Expression for genes affiliated with Migraine with Aura

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1BioGPS
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Expression patterns in normal tissues for genes affiliated with Migraine with Aura

Pathways for genes affiliated with Migraine with Aura

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34PharmGKB, 36QIAGEN, 38Reactome, 20KEGG
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Pathways related to migraine with aura according to GeneDecks:

idPathwayScoreTop Affiliating Genes
1Selective Serotonin Reuptake Inhibitor Pathway, Pharmacodynamics349.8SLC6A4, HTR2A, HTR1D
2Endothelin-1 Signaling Pathway369.2INSR, EDN1, EDNRA, EDNRB
3Amine ligand-binding receptors389.2HTR1B, HTR1D, HTR2A, HTR2C, DRD2
4Intracellular Calcium Signaling368.6CACNA1A, HTR2C, HTR2A, HTR1D, HTR1B, INSR
5Neuroactive ligand-receptor interaction208.4HTR1B, GABRA5, ADORA2A, EDNRB, EDNRA, DRD2
6Calcium signaling pathway208.3ADORA2A, EDNRB, EDNRA, NOS3, CACNA1A, HTR2C

Compounds for genes affiliated with Migraine with Aura

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32Novoseek , 9DrugBank, 34PharmGKB, 18HMDB, 42Tocris Bioscience
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Compounds related to migraine with aura according to GeneDecks:

(show top 50)    (show all 215)
idCompoundScoreTop Affiliating Genes
1yohimbine32 9 9 12.1HTR2C, DRD2, HTR1D
2bromocriptine32 9 9 12.0HTR2A, VIP, HTR2C
3ipsapirone32 9.7HTR1B, HTR1D, HTR2A, HTR2C
45-carboxamidotryptamine32 9.7HTR1B, HTR1D, HTR2A, HTR2C
5mcpp32 9.7SLC6A4, HTR1B, HTR2A, HTR2C
6metergoline32 9.7HTR1B, HTR2C, HTR1D, HTR2A
7ritanserin32 9.6HTR2A, HTR2C, HTR1D, HTR1B, DRD2
8minaprine32 9 9 11.6HTR2A, HTR2C, DRD2, SLC6A4
9methysergide32 9 9 11.6HTR2C, HTR2A, HTR1B, HTR1D
10lisuride32 9 9 11.6DRD2, HTR2C, HTR2A, HTR1D, HTR1B
113,4-Methylenedioxymethamphetamine9 9 10.6HTR2C, HTR2A, SLC6A3, SLC6A4
12ropinirole32 9 9 11.6DRD2, HTR2C, HTR2A, HTR1D, HTR1B
13pergolide32 9 9 11.5HTR2C, DRD2, HTR2A, HTR1D, HTR1B
14cabergoline32 9 9 11.5HTR1B, DRD2, HTR2C, HTR2A, HTR1D
15aripiprazole32 34 9 18 9 13.5DRD2, HTR1D, HTR1B, HTR2C, HTR2A
16ziprasidone32 9 9 11.5HTR1D, HTR2A, HTR2C, DRD2, HTR1B
17ergotamine32 9 9 11.5DRD2, HTR2A, HTR1D, HTR1B
18amine32 9.4SLC6A4, DBH, HTR2C, HTR1B, ADORA2A, HTR1D
19ketanserin32 9.4HTR1D, HTR2A, HTR2C, DRD2, SLC6A4, HTR1B
20haloperidol32 34 9 9 12.3ADORA2A, SLC6A4, HTR2A, VIP, SLC6A3
21sodium32 18 10.3SLC6A4, SLC6A3, DBH, EDNRB, CACNA1A, ATP1A2
22pramipexole32 9 9 11.2HTR2C, DRD2, HTR2A, HTR1D, HTR1B, SLC6A3
23apomorphine32 9 9 11.2HTR1D, HTR1B, HTR2A, HTR2C, DRD2, SLC6A3
24trimipramine32 34 9 9 12.2SLC6A4, SLC6A3, DRD2, HTR2A
25levodopa32 9 9 11.2DBH, SLC6A3, DRD2, ADORA2A, HTR1B, MTHFR
26risperidone32 34 9 18 9 13.2SLC6A3, SLC6A4, DRD2, HTR2C, HTR2A, HTR1D
27fluoxetine32 34 9 9 12.1SLC6A3, DRD2, SLC6A4, HTR1B, HTR2A, HTR2C
28phosphoramidon32 9 9 11.1VIP, EDN1, EDNRB, EDNRA, ACE
29sildenafil32 34 9 18 9 13.1SLC6A4, VIP, NOS3, EDN1, EDNRA
30quetiapine32 9 18 9 12.1HTR1B, HTR1D, HTR2C, HTR2A, DRD2, SLC6A3
31maoa32 9.0HTR1B, SLC6A4, SLC6A3, DBH, DRD2, HTR2C
32olanzapine32 34 9 18 9 13.0SLC6A3, DRD2, HTR2C, HTR2A, HTR1D, HTR1B
33nefazodone34 32 9 9 11.9SLC6A3, HTR2C, SLC6A4, HTR2A
34aspartate32 8.8SLC6A4, ADORA2A, VIP, SLC6A3, F5
35clozapine32 34 9 9 11.8HTR2C, ADORA2A, SLC6A4, SLC2A1, SLC6A3, DRD2
36cysteine32 8.8EDNRB, DBH, EDNRA, NOTCH3, HTR2C, INSR
37potassium32 9 18 9 11.7EDNRA, CACNA1A, VIP, EDNRB, KCNK18, SCN1A
38cocaine32 9 9 10.6ADORA2A, DBH, HTR2C, F5, HTR1B, DRD2
39glutamate32 8.6VIP, MTHFR, ATP1A2, HTR2C, INSR, SLC2A1
40verapamil32 34 9 18 9 12.4VIP, CACNA1A, EDNRB, ACE, SLC2A1, SLC6A4
41gaba32 42 9.4DBH, DRD2, HTR2C, SLC6A3, VIP, INSR
425-hydroxytryptamine32 7.8HTR2A, HTR1B, HTR2C, DRD2, EDN1, VIP
43dopamine32 9 18 9 10.7VIP, DBH, HTR2C, MTHFR, HTR1D, INSR
44prostacyclin32 7.6EDN1, NOS3, EDNRA, EDNRB, ACE, ADORA2A
45acetylcholine32 9 18 9 10.4EDN1, NOS3, EDNRB, ADORA2A, EDNRA, SLC6A3
46norepinephrine32 9 18 9 10.2EDNRA, DBH, VIP, HTR2A, HTR2C, SLC6A3
47nitric oxide32 9 18 9 10.0EDN1, EDNRA, EDNRB, DBH, ADORA2A, ACE
48calcium32 9 18 9 10.0VIP, CACNA1A, SPTAN1, EDN1, EDNRA, EDNRB
49vegf32 6.6EDN1, EDNRA, EDNRB, SLC2A1, ADORA2A, NOS3
50serine32 6.4HTR2C, F5, EDNRA, CACNA1A, SPTAN1, NOS3

GO Terms for genes affiliated with Migraine with Aura

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12Gene Ontology
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Cellular components related to migraine with aura according to GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1caveolaGO:0059018.9SLC2A1, NOS3, INSR, ATP1A2
2membraneGO:0160208.3INSR, ESR1, SPTAN1, EDNRA, DBH, SLC2A1
3integral to plasma membraneGO:0058877.5EDNRB, SLC6A3, SLC6A4, ADORA2A, GABRA5, EDNRA
4plasma membraneGO:0058864.0KCNK18, NOTCH3, EDNRA, EDNRB, ACE, SLC6A3

Biological processes related to migraine with aura according to GeneDecks:

(show all 41)
idNameGO IDScoreTop Affiliating Genes
1endothelin receptor signaling pathwayGO:08610010.3EDNRA, EDNRB
2dopamine catabolic processGO:04242010.2SLC6A3, DBH
3blood circulationGO:00801510.2ADORA2A
4behavioral response to ethanolGO:04814910.2DBH, DRD2
5response to amphetamineGO:00197510.2ADORA2A, DBH, DRD2
6visual learningGO:00854210.2DBH, DRD2, ATP1A2
7negative regulation of cellular protein metabolic processGO:03226910.1EDN1, EDNRB
8prepulse inhibitionGO:06013410.1ADORA2A, SLC6A3, DRD2
9response to iron ionGO:01003910.1SLC6A3, DBH, DRD2
10maternal process involved in parturitionGO:06013710.0EDNRA, EDN1
11response to cocaineGO:04222010.0SLC6A3, DRD2, HTR1B
12negative regulation of synaptic transmission, glutamatergicGO:05196710.0HTR1B, HTR2A, DRD2
13regulation of dopamine secretionGO:01405910.0DRD2, HTR2A, HTR1B
14negative regulation of cAMP biosynthetic processGO:03081810.0EDNRA, EDN1, HTR1B
15vein smooth muscle contractionGO:01482610.0EDNRB, EDN1
16histamine secretionGO:00182110.0EDNRA, EDN1
17positive regulation of renal sodium excretionGO:03581510.0ADORA2A, EDN1, DRD2
18positive regulation of urine volumeGO:03581010.0ADORA2A, EDN1, DRD2
19positive regulation of odontogenesisGO:0424829.9EDNRA, EDN1
20artery smooth muscle contractionGO:0148249.9EDNRA, EDN1
21elevation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathwayGO:0514829.9EDNRA, EDN1, DRD2
22locomotory behaviorGO:0076269.9DRD2, DBH, SLC6A3, ADORA2A
23protein kinase C-activating G-protein coupled receptor signaling pathwayGO:0072059.9ADORA2A, EDNRA, EDN1, HTR1B
24adenohypophysis developmentGO:0219849.8DRD2, SLC6A3
25release of sequestered calcium ion into cytosolGO:0512099.8HTR2A, HTR2C, DRD2
26response to nicotineGO:0350949.7DRD2, EDN1, SLC6A3
27vasoconstrictionGO:0423109.7SLC6A4, EDNRB, EDNRA, EDN1
28regulation of vasoconstrictionGO:0192299.7ACE, EDN1, ATP1A2
29memoryGO:0076139.7SLC6A4, DBH, HTR2A
30monoamine transportGO:0158449.6SLC6A3, SLC6A4
31sensory perception of painGO:0192339.6EDNRA, EDN1, HTR2A
32regulation of systemic arterial blood pressure by endothelinGO:0031009.6EDN1, NOS3
33blood vessel remodelingGO:0019749.5NOS3, ACE, DBH
34response to ethanolGO:0454719.5SLC6A3, NOS3, HTR1B, INSR
35regulation of blood pressureGO:0082179.4ATP1A2, NOS3, EDNRB, ACE
36agingGO:0075689.3SLC6A3, EDNRA, NOS3, HTR2A
37positive regulation of nitric oxide biosynthetic processGO:0454299.2INSR, ESR1, EDN1
38response to hypoxiaGO:0016669.1DRD2, NOS3, EDN1, EDNRA, SLC6A4
39synaptic transmissionGO:0072688.8GABRA5, SLC6A3, DBH, CACNA1A, HTR2C, HTR2A
40response to estradiol stimulusGO:0323558.8SLC6A4, DBH, NOS3, ESR1, INSR
41response to drugGO:0424938.0HTR1B, ADORA2A, SLC6A4, SLC6A3, EDN1, NOS3

Molecular functions related to migraine with aura according to GeneDecks:

(show all 7)
idNameGO IDScoreTop Affiliating Genes
1monoamine transmembrane transporter activityGO:0085049.9SLC6A3, SLC6A4
2endothelin receptor activityGO:0049629.9EDNRB, EDNRA
31-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine bindingGO:0718869.8HTR2C, HTR2A
4serotonin bindingGO:0513789.6HTR2C, HTR2A, HTR1D, HTR1B
5serotonin receptor activityGO:0049939.5HTR2C, HTR2A, HTR1D, HTR1B
6phosphatidylinositol phospholipase C activityGO:0044359.2HTR2A, HTR2C, EDNRA
7drug bindingGO:0081448.6HTR1B, HTR2A, HTR2C, DRD2, ACE, SLC6A3

Sources for Migraine with Aura

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2CDC
11FMA
18HMDB
19ICD9CM
20KEGG
24MeSH
25MGI
27NCIt
28NDF-RT
31NINDS
32Novoseek
33OMIM
35PubMed
36QIAGEN
43UMLS
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