MGR13
MCID: MGR019
MIFTS: 16

Migraine, with or Without Aura 13 (MGR13) malady

Category: Genetic diseases (common)

Aliases & Classifications for Migraine, with or Without Aura 13

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Aliases & Descriptions for Migraine, with or Without Aura 13:

Name: Migraine, with or Without Aura 13 52
Migraine with or Without Aura 13 70 27
 
Migraine, with or Without Aura, Susceptibility to, 13 12
Mgr13 70

Classifications:



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OMIM52 613656
MedGen37 C3150908

Summaries for Migraine, with or Without Aura 13

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UniProtKB/Swiss-Prot:70 Migraine with or without aura 13: A form of migraine transmitted in an autosomal dominant pattern. Migraine is a disabling symptom complex of periodic headaches, usually temporal and unilateral. Headaches are often accompanied by irritability, nausea, vomiting and photophobia, preceded by constriction of the cranial arteries. The two major subtypes are common migraine (migraine without aura) and classic migraine (migraine with aura). Classic migraine is characterized by recurrent attacks of reversible neurological symptoms (aura) that precede or accompany the headache. Aura may include a combination of sensory disturbances, such as blurred vision, hallucinations, vertigo, numbness and difficulty in concentrating and speaking.

MalaCards based summary: Migraine, with or Without Aura 13, also known as migraine with or without aura 13, is related to migraine with or without aura 1 and migraine with or without aura, susceptibility 13. An important gene associated with Migraine, with or Without Aura 13 is KCNK18 (Potassium Two Pore Domain Channel Subfamily K Member 18).

Description from OMIM:52 613656

Related Diseases for Migraine, with or Without Aura 13

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Diseases related to Migraine, with or Without Aura 13 via text searches within MalaCards or GeneCards Suite gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1migraine with or without aura 110.9
2migraine with or without aura, susceptibility 1310.8

Symptoms & Phenotypes for Migraine, with or Without Aura 13

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Clinical features from OMIM:

613656

Drugs & Therapeutics for Migraine, with or Without Aura 13

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Drugs for Migraine, with or Without Aura 13 (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 11)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Dronabinolapproved, illicitPhase 21441972-08-316078, 2978
Synonyms:
&Delta
(-)- delta 9-Tetrahydrocannabinol
(-)-.DELTA.1-Tetrahydrocannabinol
(-)-.DELTA.9-THC
(-)-.DELTA.9-Tetrahydrocannabinol
(-)-.DELTA.9-trans-Tetrahydrocannabinol
(-)-.delta.(sup9)-trans-Tetrahydrocannabinol
(-)-3,4-trans-Delta1-Tetrahydrocannabinol
(-)-delta (sup9)-trans-Tetrahydrocannabinol
(-)-delta 1-Tetrahydrocannabinol
(-)-delta 9-THC
(-)-delta 9-trans-Tetrahydrocannabinol
(-)-delta(sup 1)-3,4-trans-Tetrahydrocannabinol
(-)-delta1-Tetrahydrocannabinol
(-)-delta9-(trans)-Tetrahydrocannabinol
(-)-delta9-Tetrahydrocannabinol
(-)-delta9-trans-Tetrahydrocannabinol
(-)-trans-.DELTA.9-Tetrahydrocannabinol
(-)-trans-Delta1-Tetrahydrocannabinol
(-)-trans-Delta9-THC
(-)-trans-delta 1-Tetrahydrocannabinol
(-)-trans-delta 9-THC
(-)-trans-delta 9-Tetrahydrocannabinol
(-)-trans-delta9-Tetrahydrocannabinol
(L)-.delta.1-Tetrahydrocannabinol
(L)-delta 1-Tetrahydrocannabinol
(l)-delta(sup 1)-Tetrahydrocannabinol
(l)-delta1-Tetrahydrocannabinol
.DELTA.1-THC
.DELTA.1-Tetrahydrocannabinol
.DELTA.9-THC
.DELTA.9-trans-Tetrahydrocannabinol
.delta.(sup9)-THC
.delta.-9-THC
1-trans-.delta.(sup9)-tetrahydrocannabinol
1-trans-D9-Tetrahydrocannabinol
1-trans-delta (sup9)-tetrahydrocannabinol
1-trans-delta 9-Tetrahydrocannabinol
1-trans-delta(sup 9)-Tetrahydrocannabinol
1-trans-delta(sup9)-tetrahydrocannabinol
1-trans-delta-9-Tetrahydrocannabinol
1-trans-delta9-Tetrahydrocannabinol
1363-19-5
14146-29-3
14146-43-1
14C-.DELTA.1-Tetrahydrocannabinol
14C-delta 1-Tetrahydrocannabinol
1972-08-3
26108-45-2
3-Pentyl-6,6,9-trimethyl-6a,7,8,10a-tetrahydro-6H-dibenzo(b,D)pyran-1-ol
308064-99-5
5957-27-7
6,6,9-Trimethyl-3-pentyl-6a,7,8,10a-tetrahydro-6H-benzo[c]chromen-1-ol
6465-30-1
6H-Dibenzo
9-THC
9-delta-Tetrahydrocannabinol
9-ene-Tetrahydrocannabinol
9-tetrahydrocannabinol
AC1L277U
AC1Q2VRZ
Abbott 40566
BIDD:GT0427
C06972
CAT-310
CCRIS 4726
CHEBI:104496
CHEMBL465
CID16078
Cannabinol, Delta1-tetrahydro- (7CI)
Cannabinol, tetrahydro- (6CI)
Cannabis resin
Compassia
D00306
DB00470
DEA No. 7369
DEA No. 7370
DRG-0138
Dea No. 7369
Dea No. 7370
Delta9-Tetrahydrocannabinol solution
Deltanyne
Drona binol
Dronabinol
Dronabinol (USP/INN)
Dronabinol [USAN:INN]
 
Dronabinol [Usan:Inn]
Dronabinolum
Dronabinolum [Latin]
EPA 28
EPA-PLUS
Exocyclic delta (9)(11)-Tetrahydrocannabiol
Fats and Glyceridic oils, fish, n-3 fatty acid-high
Fish oils, n-3 fatty acid-high
Fish oils, omega-3 fatty acid-high
Ganja
HSDB 6471
Hashish
L-.delta.1-Tetrahydrocannabinol
L-.delta.1-trans-Tetrahydrocannabinol
L-delta 1-trans-Tetrahydrocannabinol
L-delta(sup 1)-tetrahydrocannabinol
L-delta1-trans-Tetrahydrocannabinol
L-trans-.delta.9-Tetrahydrocannabinol
L-trans-delta 9-Tetrahydrocannabinol
L-trans-delta9-Tetrahydrocannabinol
LS-975
Marincap
Marinol
Marinol (TN)
MaxEPA
MolPort-003-959-698
NSC 134454
NSC134454
Namisol
Omegaven
PDSP2_000714
Primolut
Pro-Mega
Promega
QCD 84924
QCD-84924
Relivar
SP 104
Sonergx
T2386_SIGMA
T4764_FLUKA
T4764_SIGMA
TETRAHYDROCANNABINOL
THC
THC-delta-9
Tetrahydrocannabinol
Tetrahydrocannabinol delta9
Tetrahydrocannabinols (-)-delta1-3,4-trans-form
Tetranabinex
UNII-7J8897W37S
ZINC01530625
delta (sup9)-Thc
delta 1-THC
delta 1-Tetrahydrocannabinol
delta 9-THC
delta 9-Tetrahydrocannabinol
delta 9-trans-Tetrahydrocannabinol
delta(1)-THC
delta(1)-Tetrahydrocannabinol
delta(9)-THC
delta(9)-Tetrahydrocannabinol
delta(9)-Tetrahydrocannibinol
delta(sup 1)-Tetrahydrocannabinol
delta(sup 1)-Thc
delta(sup 9)-Tetrahydrocannabinol
delta(sup 9)-Thc
delta-9-THC
delta-9-Tetrahydrocannabinol
delta-9-tetrahydrocannabinol
delta-THC
delta1-THC
delta1-Tetrahydrocannabinol
delta1-Tetrahydrocannabinol (VAN)
delta9-THC
delta9-Tetrahydrocannabinol
delta9-Tetrahydrocannabinol (VAN)
delta9-trans-Tetrahydrocannabinol
nchembio.129-comp1
nchembio.552-comp1
nchembio.86-comp3
omega-3-Fatty acid
trans-.DELTA.9-Tetrahydrocannabinol
trans-delta (-)-9-Tetrahydrocannabinol
trans-delta 9-Tetrahydrocannabinol
trans-delta-9-Tetrahydrocannabinol
trans-delta9-Tetrahydrocannabinol
trans-tetrahydrocannabinol
Δ9-tetrahydrocannabinol
2Neurotransmitter AgentsPhase 218340
3Hormones, Hormone Substitutes, and Hormone AntagonistsPhase 213168
4Peripheral Nervous System AgentsPhase 223689
5Psychotropic DrugsPhase 26430
6HormonesPhase 214415
7Hormone AntagonistsPhase 213180
8Analgesics, Non-NarcoticPhase 26501
9Cannabinoid Receptor AgonistsPhase 2125
10HallucinogensPhase 2179
11AnalgesicsPhase 211733

Interventional clinical trials:

idNameStatusNCT IDPhase
1DFN-11 Injection in Episodic Migraine With or Without AuraActive, not recruitingNCT02569853Phase 3
2Study to Evaluate the Efficacy and Safety of Dronabinol Metered Dose Inhaler (MDI) in Acute Treatment of Migraine HeadacheCompletedNCT00123201Phase 2

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Genetic Tests for Migraine, with or Without Aura 13

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Genetic tests related to Migraine, with or Without Aura 13:

id Genetic test Affiliating Genes
1 Migraine, with or Without Aura 1327

Anatomical Context for Migraine, with or Without Aura 13

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Publications for Migraine, with or Without Aura 13

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Variations for Migraine, with or Without Aura 13

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Clinvar genetic disease variations for Migraine, with or Without Aura 13:

5
id Gene Variation Type Significance SNP ID Assembly Location
1KCNK18NM_ 181840.1(KCNK18): c.414_ 415delCT (p.Phe139Trpfs)deletionrisk factorrs869025175GRCh37Chr 10, 118969069: 118969070

Expression for genes affiliated with Migraine, with or Without Aura 13

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Search GEO for disease gene expression data for Migraine, with or Without Aura 13.

Pathways for genes affiliated with Migraine, with or Without Aura 13

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GO Terms for genes affiliated with Migraine, with or Without Aura 13

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Sources for Migraine, with or Without Aura 13

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet