MCID: MLL002
MIFTS: 38

Miller Fisher Syndrome malady

Rare diseases, Neuronal diseases, Immune diseases categories
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Summaries for Miller Fisher Syndrome

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NIH Rare Diseases:42 Miller-fisher syndrome is a rare, acquired nerve disease that is considered to be a variant of guillain-barré syndrome. it is characterized by abnormal muscle coordination, paralysis of the eye muscles, and absence of the tendon reflexes. like guillain-barré syndrome, symptoms may be preceded by a viral illness. additional symptoms include generalized muscle weakness and respiratory failure. the majority of individuals with miller-fisher syndrome have a unique antibody that characterizes the disorder. treatment includes intravenous immunoglobulin (ivig) or plasmapheresis (a procedure in which antibodies are removed from the blood) and supportive care. last updated: 10/21/2011

MalaCards based summary: Miller Fisher Syndrome, also known as cranial variant of guillain-barré syndrome, is related to ophthalmoplegia and encephalitis. An important gene associated with Miller Fisher Syndrome is SRF (serum response factor (c-fos serum response element-binding transcription factor)). The compound tyrosine have been mentioned in the context of this disorder. Affiliated tissues include eye, brain and lung.

Disease Ontology:8 A guillain-barre syndrome that manifests as a descending paralysis. it usually affects the eye muscles first and presents with the triad of ophthalmoplegia, ataxia, and areflexia.

NINDS:43 Miller Fisher syndrome is a rare, acquired nerve disease that is considered to be a variant of Guillain-Barr

Wikipedia:65 Guillain?Barr more...

Aliases & Classifications for Miller Fisher Syndrome

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Sources:
8Disease Ontology, 42NIH Rare Diseases, 43NINDS, 10DISEASES, 44Novoseek, 48Orphanet, 62UMLS, 34MeSH, 57SNOMED-CT, 35MESH via Orphanet, 26ICD10 via Orphanet, 63UMLS via Orphanet
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Miller Fisher Syndrome, Aliases & Descriptions:

Name: Miller Fisher Syndrome 8 43 10 44 62
Cranial Variant of Guillain-Barré Syndrome 42 48
Miller-Fisher Syndrome 42 48
Cranial Variant of Gbs 42 48
 
Fisher Syndrome 48 62
Miller-Fisher Variant of Guillain-Barre Syndrome 8
Fisher's Syndrome 8


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases
Anatomical: Neuronal diseases, Immune diseases


Characteristics (Orphanet epidemiological data):

48
cranial variant of guillain-barré syndrome:
Inheritance: Multigenic/multifactorial,Sporadic; Prevalence: 1-9/1000000; Age of onset: Variable; Age of death: Any age


External Ids:

Disease Ontology8 DOID:12889
MeSH34 D019846
MESH via Orphanet35 D019846
ICD10 via Orphanet26 G61.0
UMLS via Orphanet63 C0393799

Related Diseases for Miller Fisher Syndrome

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Graphical network of the top 20 diseases related to Miller Fisher Syndrome:



Diseases related to miller fisher syndrome

Symptoms for Miller Fisher Syndrome

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Drugs & Therapeutics for Miller Fisher Syndrome

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Drug clinical trials:

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Genetic Tests for Miller Fisher Syndrome

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Anatomical Context for Miller Fisher Syndrome

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MalaCards organs/tissues related to Miller Fisher Syndrome:

32
Eye, Brain, Lung, Testes, B cells, Dorsal root ganglion

Animal Models for Miller Fisher Syndrome or affiliated genes

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Publications for Miller Fisher Syndrome

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Articles related to Miller Fisher Syndrome:

(show top 50)    (show all 243)
idTitleAuthorsYear
1
A Case of Neuromyelitis Optica Masquerading as Miller Fisher Syndrome. (25408664)
2014
2
Miller Fisher syndrome with presynaptic neuromuscular transmission disorder. (25300589)
2014
3
Postvaccination Miller Fisher syndrome after combined pertussis, diphtheria and tetanus toxoid vaccine. (23219950)
2013
4
Miller Fisher syndrome with positivity of anti-GAD antibodies. (23253818)
2013
5
Miller-Fisher syndrome following vaccination against influenza virus A/H1N1 in an AIDS patient. (21877180)
2012
6
Recurrent Miller Fisher syndrome: clinical and laboratory features. (22117529)
2012
7
Symptomatic Recovery in Miller Fisher Syndrome Parallels Vestibular-Perceptual and not Vestibular-Ocular Reflex Function. (21350734)
2011
8
Miller-Fisher syndrome in a patient with rheumatoid arthritis treated with adalimumab. (18818868)
2009
9
Molecular imaging provides a hint that Miller Fisher syndrome might involve the central nervous system. (19372284)
2009
10
Miller Fisher syndrome in a 66-year-old female after flu and pneumovax vaccinations. (18457810)
2008
11
A combined presentation of Graves' disease and Miller-Fisher syndrome. (18514733)
2008
12
Optic neuritis in a patient with Miller-Fisher syndrome. (19133529)
2008
13
Long-term transvenous temporary pacing with active fixation bipolar lead in the management of severe autonomic dysfunction in Miller-Fisher syndrome: a case report. (17267055)
2007
14
Unilateral external ophthalmoplegia in Miller Fisher syndrome: case report. (17439660)
2007
15
Miller Fisher syndrome associated with Burkitt's lymphoma. (16643330)
2006
16
Anti-GQ1b-negative Miller-Fisher syndrome with lower cranial nerve involvement from parasinusoidal aspergilloma. (16081159)
2006
17
Recent developments in Miller Fisher syndrome and related disorders. (16155441)
2005
18
An antibody to VacA of Helicobacter pylori in the CSF of patients with Miller-Fisher syndrome. (15596779)
2004
19
Miller Fisher syndrome associated with Pasteurella multocida infection. (15548510)
2004
20
Miller Fisher syndrome with transient coma: comparison with Bickerstaff brainstem encephalitis. (11891101)
2002
21
Clinical, electrophysiological, and serological overlap between Miller Fisher syndrome and acute sensory ataxic neuropathy. (11982496)
2002
22
Combined pre- and postsynaptic action of IgG antibodies in Miller Fisher syndrome. (11148238)
2001
23
Guillain-BarrAc syndrome- and Miller Fisher syndrome-associated Campylobacter jejuni lipopolysaccharides induce anti-GM1 and anti-GQ1b Antibodies in rabbits. (11254608)
2001
24
Miller Fisher syndrome in an elderly man. (11443034)
2001
25
Transcranial magnetic stimulation studies in the Miller Fisher syndrome: evidence of corticospinal tract abnormality. (11459894)
2001
26
Amplified fragment length polymorphism analysis of Campylobacter jejuni strains isolated from chickens and from patients with gastroenteritis or Guillain-BarrAc or Miller Fisher syndrome. (10966409)
2000
27
Ataxic Guillain-BarrAc syndrome with anti-GQ1b antibody: relation to Miller Fisher syndrome. (10802797)
2000
28
The Miller Fisher syndrome: neurophysiological and MRI evidence of both peripheral and central origin in one case. (11200697)
2000
29
Miller Fisher syndrome: axonal, demyelinating or both? (11155543)
2000
30
Miller Fisher syndrome: an uncommon acute neuropathy. (10802419)
2000
31
Pre- and postsynaptic blockade of neuromuscular transmission by Miller-Fisher syndrome IgG at mouse motor nerve terminals. (9753137)
1998
32
Neurosyphilis mimicking Miller-Fisher syndrome: a case report and MRI findings. (9674818)
1998
33
Lumbosacral root and facial nerve enhancement in Miller Fisher syndrome. (9808248)
1998
34
Development of facial palsy during immunoadsorption plasmapheresis in Miller Fisher syndrome: a clinical report of two cases. (9527160)
1998
35
Humoral immune response against Campylobacter jejuni lipopolysaccharides in Guillain-BarrAc and Miller Fisher syndrome. (9357448)
1997
36
A neurophysiological study in children with Miller Fisher syndrome and Guillain-Barre syndrome. (9134191)
1997
37
Atypical Miller Fisher syndrome with GQ1b antibodies. (18638884)
1996
38
Cranial nerve enhancement on three-dimensional MRI in Miller Fisher syndrome. (8960757)
1996
39
Miller Fisher syndrome and anti-GQ1b antibodies. (7779653)
1995
40
Neoplastic meningitis presenting with ophthalmoplegia, ataxia, and areflexia (Miller-Fisher syndrome) (7733836)
1995
41
Miller Fisher syndrome associated with Mycoplasma pneumoniae infection: report of a case. (8187390)
1994
42
Miller-Fisher syndrome with rapid recovery. (7910293)
1994
43
High dose immunoglobulin therapy is effective in the Miller Fisher syndrome. (8164023)
1994
44
Brainstem encephalitis and the Miller Fisher syndrome. (8382270)
1993
45
Pediatric Miller Fisher syndrome requiring intubation: a case report. (8344052)
1993
46
Miller Fisher syndrome associated with Q fever. (2391529)
1990
47
Miller Fisher syndrome: an electrophysiologic case study. (3168912)
1988
48
Divergence paralysis as the initial sign in the Miller Fisher syndrome. (3717265)
1986
49
Abscence of CNS lesion in autopsied patients with Miller-Fisher syndrome. (3966876)
1985
50
Peripheral nerve conduction in Miller Fisher syndrome. (925702)
1977

Variations for Miller Fisher Syndrome

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Expression for genes affiliated with Miller Fisher Syndrome

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Expression patterns in normal tissues for genes affiliated with Miller Fisher Syndrome

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Pathways for genes affiliated with Miller Fisher Syndrome

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Compounds for genes affiliated with Miller Fisher Syndrome

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Sources:
44Novoseek
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Compounds related to Miller Fisher Syndrome according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1tyrosine449.1SIGLEC7, SRF

GO Terms for genes affiliated with Miller Fisher Syndrome

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Products for genes affiliated with Miller Fisher Syndrome

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  • Antibodies
  • Proteins
  • Lysates

Sources for Miller Fisher Syndrome

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet