Mirror Movements 1 malady
Categories: Genetic diseases, Rare diseases, Neuronal diseases
Aliases & Descriptions for Mirror Movements 1:
Orphanet epidemiological data:53
hereditary congenital controlateral synkinesia:
Inheritance: Autosomal dominant; Prevalence: <1/1000000 (Worldwide); Age of onset: Childhood,Infancy; Age of death: normal life expectancy
Penetrance: penetrance does not appear to be sex-related or age-related, as mirror movements are present from early childhood in all symptomatic individuals...
Global: Genetic diseases, Rare diseases
Anatomical: Neuronal diseases
Rare neurological diseases
NIH Rare Diseases:47 Congenital mirror movement disorder (CMM) is a rare condition that is characterized by mirror movements (involuntary movements of one side of the body that mirror intentional movements on the opposite side). Affected people generally develop these movements in infancy or early childhood, which usually persist throughout their life without any related signs or symptoms. In most cases, the involuntary movements are noticeable but less pronounced than the corresponding voluntary movements; however, the severity of symptoms can vary significantly, even among family members. CMM can be caused by changes (mutations) in the DCC or RAD51 genes and inherited in an autosomal dominant manner. In some families, the exact underlying cause of CMM is unknown. Last updated: 5/4/2015
MalaCards based summary: Mirror Movements 1, also known as congenital mirror movements, is related to mirror movements 2 and mirror movements 3, and has symptoms including bimanual synkinesia An important gene associated with Mirror Movements 1 is DCC (DCC Netrin 1 Receptor), and among its related pathways are Pathways in cancer and Integrated Pancreatic Cancer Pathway. Affiliated tissues include spinal cord and brain.
Genetics Home Reference:25 Congenital mirror movement disorder is a condition in which intentional movements of one side of the body are mirrored by involuntary movements of the other side. For example, when an affected individual makes a fist with the right hand, the left hand makes a similar movement. The mirror movements in this disorder primarily involve the upper limbs, especially the hands and fingers. This pattern of movements is present from infancy or early childhood and usually persists throughout life, without other associated signs and symptoms. Intelligence and lifespan are not affected.
OMIM:51 Mirror movements are contralateral involuntary movements that mirror voluntary ones. Whereas mirror movements are... (157600) more...
UniProtKB/Swiss-Prot:69 Mirror movements 1: A disorder characterized by contralateral involuntary movements that mirror voluntary ones. While mirror movements are occasionally found in young children, persistence beyond the age of 10 is abnormal. Mirror movements occur more commonly in the upper extremities.
GeneReviews for NBK279760
Diseases in the Mirror Movements 1 family:
Diseases related to Mirror Movements 1 via text searches within MalaCards or GeneCards Suite gene sharing:(show all 16)
Graphical network of diseases related to Mirror Movements 1:
Drugs for Mirror Movements 1 (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):(show all 9)
Interventional clinical trials:(show all 32)
Search NIH Clinical Center for Mirror Movements 1
MalaCards organs/tissues related to Mirror Movements 1:35
Spinal cord, Brain
Clinvar genetic disease variations for Mirror Movements 1:5 (show all 11)
Search GEO for disease gene expression data for Mirror Movements 1.
30ICD10 via Orphanet
39MESH via Orphanet
52OMIM via Orphanet
62SNOMED-CT via Orphanet
66Tumor Gene Family of Databases
68UMLS via Orphanet