MCID: MRR011
MIFTS: 19

Mirror Movements 1 malady

Genetic diseases, Neuronal diseases, Rare diseases categories
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Summaries for Mirror Movements 1

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MalaCards based summary: Mirror Movements 1, also known as hereditary congenital controlateral synkinesia, is related to breast cancer, and has symptoms including An important gene associated with Mirror Movements 1 is DCC (deleted in colorectal carcinoma), and among its related pathways are Pathways in cancer and Integrated Pancreatic Cancer Pathway. Related mouse phenotype cellular.

Descriptions from OMIM:46 157600,614508

Aliases & Classifications for Mirror Movements 1

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Mirror Movements 1, Aliases & Descriptions:

Name: Mirror Movements 1 46
Hereditary Congenital Controlateral Synkinesia 48
Isolated Congenital Controlateral Synkinesia 48
Familial Congenital Controlateral Synkinesia 48
 
Hereditary Congenital Mirror Movements 48
Isolated Congenital Mirror Movements 48
Familial Congenital Mirror Movements 48


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Genetic diseases, Rare diseases
Anatomical: Neuronal diseases


Characteristics (Orphanet epidemiological data):

48
hereditary congenital controlateral synkinesia:
Inheritance: Autosomal dominant; Prevalence: <1/1000000; Age of onset: Neonatal/infancy


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Related Diseases for Mirror Movements 1

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Diseases in the Mirror Movements 1 family:

Mirror Movements 2 Mirror Movements 3

Diseases related to Mirror Movements 1 via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1breast cancer9.9RAD51, DCC

Symptoms for Mirror Movements 1

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Symptoms by clinical synopsis from OMIM:

157600

Clinical features from OMIM:

157600,614508

HPO human phenotypes related to Mirror Movements 1:

id Description Frequency HPO Source Accession
1 autosomal dominant inheritance HP:0000006
2 bimanual synkinesia HP:0001335
3 incomplete penetrance HP:0003829

Drugs & Therapeutics for Mirror Movements 1

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Drug clinical trials:

Search ClinicalTrials for Mirror Movements 1

Search NIH Clinical Center for Mirror Movements 1

Genetic Tests for Mirror Movements 1

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Anatomical Context for Mirror Movements 1

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Animal Models for Mirror Movements 1 or affiliated genes

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MGI Mouse Phenotypes related to Mirror Movements 1:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053849.1RAD51, DCC

Publications for Mirror Movements 1

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Variations for Mirror Movements 1

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Clinvar genetic disease variations for Mirror Movements 1:

6
id Gene Name Type Significance SNP ID Assembly Location
1DCCDCC, IVS6, G-A, +1single nucleotide variantPathogenic
2DCCDCC, 1-BP INS, 571GinsertionPathogenic
3DCCDCC, 2-BP DEL, 3835CTdeletionPathogenic
4RAD51NM_002875.4(RAD51): c.760C> T (p.Arg254Ter)single nucleotide variantrisk factorrs199925463GRCh37Chr 15, 41021818: 41021818
5RAD51RAD51, 1-BP DUP, 855AduplicationPathogenic

Expression for genes affiliated with Mirror Movements 1

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Expression patterns in normal tissues for genes affiliated with Mirror Movements 1

Search GEO for disease gene expression data for Mirror Movements 1.

Pathways for genes affiliated with Mirror Movements 1

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Pathways related to Mirror Movements 1 according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.1RAD51, DCC
29.1RAD51, DCC

Compounds for genes affiliated with Mirror Movements 1

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GO Terms for genes affiliated with Mirror Movements 1

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Molecular functions related to Mirror Movements 1 according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1identical protein bindingGO:0428029.1RAD51, DCC

Products for genes affiliated with Mirror Movements 1

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  • Antibodies
  • Proteins
  • Lysates

Sources for Mirror Movements 1

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet